{ "uniprot_canonical_ac": "A0A1B0GSN5-1", "uniprot_ac": "A0A1B0GSN5", "uniprot_id": "A0A1B0GSN5_MOUSE", "mass": { "chemical_mass": 35906.0, "monoisotopic_mass": 35906.0 }, "refseq": { "ac": "NP_001011755", "name": "olfactory receptor family 52 subfamily E member 8", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001011755" }, "gene_names": [ { "name": "Or52e8", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A0A1B0GSN5", "id": "A0A1B0GSN5" }, { "name": "MOR32-12; Olfr671", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001011755", "id": "NP_001011755" }, { "name": "Olfr671", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A0A1B0GSN5", "id": "A0A1B0GSN5" }, { "name": "Or52e8", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001011755", "id": "NP_001011755" } ], "protein_names": [ { "name": "Olfactory receptor", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "A0A1B0GSN5" }, { "name": "olfactory receptor MOR32-12; GA_x6K02T2PBJ9-7604826-7603885; olfactory receptor 671", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001011755", "id": "NP_001011755" }, { "name": "olfactory receptor family 52 subfamily E member 8", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001011755", "id": "NP_001011755" } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001011755", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001011755" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A0A1B0GSN5", "url": "https://www.uniprot.org/uniprot/A0A1B0GSN5" } ], "common_name": "Mouse" } ], "gene": [ { "name": "Or52e8", "url": "https://www.uniprot.org/uniprot/A0A1B0GSN5", "locus": { "chromosome": "7", "start_pos": 104622103, "end_pos": 104628333, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSMUSG00000094531", "url": "https://www.ensembl.org/id/ENSMUSG00000094531" } ] } } ], "crossref": [ { "id": "cd15952", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15952", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "257910", "url": "https://www.ncbi.nlm.nih.gov/gene/257910", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "mmu:257910", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:257910", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "3030505", "url": "http://www.informatics.jax.org/marker/MGI:3030505", "database": "MGI", "categories": [ "Organism-specific" ] }, { "id": "4578140at2759", "url": "http://www.orthodb.org/?query=4578140at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26450", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR26450:SF170", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450:SF170", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "http://pfam.xfam.org/family/PF13853", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "A0A1B0GSN5", "url": "https://www.uniprot.org/uniprot/A0A1B0GSN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1B0GSN5-1", "url": "https://www.uniprot.org/uniprot/A0A1B0GSN5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q7TRP2", "url": "https://www.uniprot.org/uniprot/Q7TRP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q7TRP2-1", "url": "https://www.uniprot.org/uniprot/Q7TRP2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTERMSLYNVTEVHPSSFLLLGIPGLENAHIWIGFPFCLLYLIAVLGNGAVLFVIQAEHSLHEPMYYFLAMLDSIDLGLTTATIPKMLGIFWFNLREISFGGCLSQMFFIHFFTAMESIMLLAMGFDRYIAICKPLQYTVILTNKVIGVIAGIAVLRSLYMVLPLVFLLLRLPYCGHQSIPHTYCEHMGIARLACASIKVNIMFGLSNIALLLLDVVLIILSYVRILYAVFCLPSREARLKALNTCGSHIGVILTFFTPAFFSFLTHRFGHNVPQYIHIFLANLYVVVPPALNPVIYGVRTKQIRERVMRILFHKDH", "length": 317, "header": "tr|A0A1B0GSN5-1|A0A1B0GSN5_MOUSE Isoform 1 of Olfactory receptor OS=Mus musculus OX=10090 GN=Or52e8 PE=3 SV=1 CANONICAL=A0A1B0GSN5-1" }, "isoforms": [ { "isoform_ac": "A0A1B0GSN5-1", "url": "", "sequence": { "sequence": "MTERMSLYNVTEVHPSSFLLLGIPGLENAHIWIGFPFCLLYLIAVLGNGAVLFVIQAEHSLHEPMYYFLAMLDSIDLGLTTATIPKMLGIFWFNLREISFGGCLSQMFFIHFFTAMESIMLLAMGFDRYIAICKPLQYTVILTNKVIGVIAGIAVLRSLYMVLPLVFLLLRLPYCGHQSIPHTYCEHMGIARLACASIKVNIMFGLSNIALLLLDVVLIILSYVRILYAVFCLPSREARLKALNTCGSHIGVILTFFTPAFFSFLTHRFGHNVPQYIHIFLANLYVVVPPALNPVIYGVRTKQIRERVMRILFHKDH", "length": 317, "header": "tr|A0A1B0GSN5-1|A0A1B0GSN5_MOUSE Isoform 1 of Olfactory receptor OS=Mus musculus OX=10090 GN=Or52e8 PE=3 SV=1 CANONICAL=A0A1B0GSN5-1" }, "locus": { "chromosome": "7", "start_pos": 104625202, "end_pos": 104624252, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000217091.2", "url": "https://www.ensembl.org/id/ENSMUST00000217091.2" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000150911.2", "url": "https://www.ensembl.org/id/ENSMUSP00000150911.2" } ] } }, { "isoform_ac": "Q7TRP2-1", "url": "", "sequence": { "sequence": "MSLYNVTEVHPSSFLLLGIPGLENAHIWIGFPFCLLYLIAVLGNGAVLFVIQAEHSLHEPMYYFLAMLDSIDLGLTTATIPKMLGIFWFNLREISFGGCLSQMFFIHFFTAMESIMLLAMGFDRYIAICKPLQYTVILTNKVIGVIAGIAVLRSLYMVLPLVFLLLRLPYCGHQSIPHTYCEHMGIARLACASIKVNIMFGLSNIALLLLDVVLIILSYVRILYAVFCLPSREARLKALNTCGSHIGVILTFFTPAFFSFLTHRFGHNVPQYIHIFLANLYVVVPPALNPVIYGVRTKQIRERVMRILFHKDH", "length": 313, "header": "tr|Q7TRP2-1|A0A1B0GSN5_MOUSE Computationally mapped isoform of Olfactory receptor OS=Mus musculus OX=10090 GN=Or52e8 PE=3 SV=1 CANONICAL=A0A1B0GSN5-1" }, "locus": { "chromosome": "7", "start_pos": 104625190, "end_pos": 104624252, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000078710.2", "url": "https://www.ensembl.org/id/ENSMUST00000078710.2" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000077774.2", "url": "https://www.ensembl.org/id/ENSMUSP00000077774.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "mmu:257910", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:257910", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZXV3-1", "protein_name": "Olfactory receptor", "gene_name": "Or52e8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTERMSLSNDTQAHPSSFLLLGIPGLEDAHIWIGFPFCFLYLIAILGNVAILFVIQTEHSLHEPMYYFLAMLDSIDLGLTTATIPKMLGIFWFNLREISFGGCLSQMFFIHFFTVMESITLLVMGFDRYIGICKPLQYTVILTTKIIGVIAGIAVLRSLYIVVPLVFLLLRLPYCGHHIIPHTYCEHMGIARLACASIRVNIMFGLSNIALLLLDVVLIILSYVRILYAVFCLPSREARLKALNTCGSHIAVLTFFTPAFFSFLTHGFGYNVPQYIHIFLANLYVVFPPALNPLIYGVRTKQIRARVMRIFFQKDD", "length": 316 }, "evidence": [ { "id": "45224803", "url": "http://www.informatics.jax.org/homology/45224803", "database": "MGI" } ], "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A3G1-1", "protein_name": "Olfactory receptor", "gene_name": "Or52e8b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTERMSLSNDTQAHPSSFLLLGIPGLEDAHVWIGFPFCFLYLIAILGNAAILFVIQTEHSLHEPMYYFLAMLDSIDLGLTTATIPKMLGIFWFDLREISFGGCLSQMFFIHFFTVMESITLLVMGFDRYIAICKPLQYTVILTTKVIVVIAGIAVLRSLYMVVPLVFLLLRLPYCGHHIIPHTYCEHMGIARLACASIRVNIMFGLSNIALLLLDVVLIILSYVRILYAVFCLPSREARLKALNTCGSHIGVILTFFTPAFFSFLTHRFGHNVPQYIHIFLANLYVVVPPALNPLIYGVRTKQIRERVMRLFFQKGN", "length": 317 }, "evidence": [ { "id": "45224803", "url": "http://www.informatics.jax.org/homology/45224803", "database": "MGI" } ], "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6IFG1-1", "protein_name": "Olfactory receptor 52E8", "gene_name": "OR52E8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGRMSTSNHTQFHPSSFLLLGIPGLEDVHIWIGVPFFFVYLVALLGNTALLFVIQTEQSLHEPMYYFLAMLDSIDLGLSTATIPKMLGIFWFNTKEISFGGCLSHMFFIHFFTAMESIVLVAMAFDRYIAICKPLRYTMILTSKIISLIAGIAVLRSLYMVVPLVFLLLRLPFCGHRIIPHTYCEHMGIARLACASIKVNIRFGLGNISLLLLDVILIILSYVRILYAVFCLPSWEARLKALNTCGSHIGVILAFFTPAFFSFLTHRFGHNIPQYIHIILANLYVVVPPALNPVIYGVRTKQIRERVLRIFLKTNH", "length": 317 }, "evidence": [ { "id": "45224803", "url": "http://www.informatics.jax.org/homology/45224803", "database": "MGI" } ], "common_name": "Human" }, { "uniprot_canonical_ac": "Q96RD3-1", "protein_name": "Olfactory receptor 52E6", "gene_name": "OR52E6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPIANDTQFHTSSFLLLGIPGLEDVHIWIGFPFFSVYLIALLGNAAIFFVIQTEQSLHEPMYYCLAMLDSIDLSLSTATIPKMLGIFWFNIKEISFGGYLSQMFFIHFFTVMESIVLVAMAFDRYIAICKPLWYTMILTSKIISLIAGIAVLRSLYMVIPLVFLLLRLPFCGHRIIPHTYCEHMGIARLACASIKVNIMFGLGSISLLLLDVLLIILSHIRILYAVFCLPSWEARLKALNTCGSHIGVILAFSTPAFFSFFTHCFGHDIPQYIHIFLANLYVVVPPTLNPVIYGVRTKHIRETVLRIFFKTDH", "length": 313 }, "evidence": [ { "id": "45224803", "url": "http://www.informatics.jax.org/homology/45224803", "database": "MGI" } ], "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A1B0GSN5", "url": "https://www.uniprot.org/uniprot/A0A1B0GSN5" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A1B0GSN5", "url": "https://www.uniprot.org/uniprot/A0A1B0GSN5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A1B0GSN5", "url": "https://www.uniprot.org/uniprot/A0A1B0GSN5" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A1B0GSN5", "url": "https://www.uniprot.org/uniprot/A0A1B0GSN5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A1B0GSN5", "url": "https://www.uniprot.org/uniprot/A0A1B0GSN5" } ], "pmid": "" }, { "name": "sensory perception of smell", "id": "GO:0007608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007608", "evidence": [ { "database": "UniProtKB", "id": "A0A1B0GSN5", "url": "https://www.uniprot.org/uniprot/A0A1B0GSN5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 9, "end_pos": 11, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "synthesized_glycans": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.mgi", "label": "MGI Homologs" } ], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": 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