{ "uniprot_canonical_ac": "A0A140TAJ4-1", "uniprot_ac": "A0A140TAJ4", "uniprot_id": "A0A140TAJ4_RAT", "mass": { "chemical_mass": 40709.0, "monoisotopic_mass": 40709.0 }, "refseq": {}, "gene_names": [ { "name": "Hsd3b5-ps1", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A0A140TAJ4", "id": "A0A140TAJ4" } ], "protein_names": [ { "name": "3-beta hydroxysteroid dehydrogenase/isomerase domain-containing protein", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "A0A140TAJ4" } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A140TAJ4", "url": "https://www.uniprot.org/uniprot/A0A140TAJ4" } ], "common_name": "Rat" } ], "gene": [ { "name": "Hsd3b5-ps1", "url": "https://www.uniprot.org/uniprot/A0A140TAJ4", "locus": {} } ], "crossref": [ { "id": "ENSRNOG00000042884", "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000042884", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR002225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HRESTWP", "url": "https://omabrowser.org/oma/group/HRESTWP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR10366", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10366", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10366:SF297", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10366:SF297", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01073", "url": "http://pfam.xfam.org/family/PF01073", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "1589580", "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1589580", "database": "RGD", "categories": [ "Organism-specific" ] }, { "id": "A0A140TAJ4", "url": "https://www.uniprot.org/uniprot/A0A140TAJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A140TAJ4-1", "url": "https://www.uniprot.org/uniprot/A0A140TAJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPGWSCLVTGAGGFLGQRIVQMLVQEKELQEVRVLYRTFSPKHKEEVSKLQTKAKVMVLKGDIVDAQFLRRACQGISVVIHTAAALDLFGTASRQTIIDVDLKGTQLLLDACVEARVPAFVYSSSTGVAGPNSYKETILNDREEEHRESTWPDPYPYSIRMAEKVVLAANGSILKNGGTLHTCALRLPFIYGEESQIISTMVNTALKNNSILKRHATFSIANPVYVGNAAWAHILAARGLRDPKKSQSIQGQFYYISDDTPHQSYDDLNYTLSKEWGFCLDSSWSLPLPLFLLRPFYNYRPPFNRFMVTILNSVFTVSYKKAQRDLGYEPLDSWEEAKQKTSEWIGTLVEQHRETLDTKSQ", "length": 361, "header": "tr|A0A140TAJ4-1|A0A140TAJ4_RAT Isoform 1 of 3-beta hydroxysteroid dehydrogenase/isomerase domain-containing protein OS=Rattus norvegicus OX=10116 GN=Hsd3b5-ps1 PE=3 SV=2 CANONICAL=A0A140TAJ4-1" }, "isoforms": [ { "isoform_ac": "A0A140TAJ4-1", "url": "", "sequence": { "sequence": "MPGWSCLVTGAGGFLGQRIVQMLVQEKELQEVRVLYRTFSPKHKEEVSKLQTKAKVMVLKGDIVDAQFLRRACQGISVVIHTAAALDLFGTASRQTIIDVDLKGTQLLLDACVEARVPAFVYSSSTGVAGPNSYKETILNDREEEHRESTWPDPYPYSIRMAEKVVLAANGSILKNGGTLHTCALRLPFIYGEESQIISTMVNTALKNNSILKRHATFSIANPVYVGNAAWAHILAARGLRDPKKSQSIQGQFYYISDDTPHQSYDDLNYTLSKEWGFCLDSSWSLPLPLFLLRPFYNYRPPFNRFMVTILNSVFTVSYKKAQRDLGYEPLDSWEEAKQKTSEWIGTLVEQHRETLDTKSQ", "length": 361, "header": "tr|A0A140TAJ4-1|A0A140TAJ4_RAT Isoform 1 of 3-beta hydroxysteroid dehydrogenase/isomerase domain-containing protein OS=Rattus norvegicus OX=10116 GN=Hsd3b5-ps1 PE=3 SV=2 CANONICAL=A0A140TAJ4-1" }, "locus": { "chromosome": "2", "start_pos": 186074459, "end_pos": 186063309, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000068511.4", "url": "https://www.ensembl.org/id/ENSRNOT00000068511.4" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000062582.4", "url": "https://www.ensembl.org/id/ENSRNOP00000062582.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A140TAJ4", "url": "https://www.uniprot.org/uniprot/A0A140TAJ4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "3-beta-hydroxy-delta5-steroid dehydrogenase activity", "id": "GO:0003854", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003854", "evidence": [ { "database": "UniProtKB", "id": "A0A140TAJ4", "url": "https://www.uniprot.org/uniprot/A0A140TAJ4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "steroid biosynthetic process", "id": "GO:0006694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006694", "evidence": [ { "database": "UniProtKB", "id": "A0A140TAJ4", "url": "https://www.uniprot.org/uniprot/A0A140TAJ4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 170, "end_pos": 172, "annotation": "n_glycosylation_sequon" }, { "start_pos": 208, "end_pos": 210, "annotation": "n_glycosylation_sequon" }, { "start_pos": 269, "end_pos": 271, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "synthesized_glycans": [], "cluster_types": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }