{ "uniprot_canonical_ac": "A0A140LHF2-1", "uniprot_ac": "A0A140LHF2", "uniprot_id": "VSXL2_MOUSE", "mass": { "chemical_mass": 83270.0, "monoisotopic_mass": 83270.0 }, "refseq": {}, "gene_names": [ { "name": "Vsig10l2", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A0A140LHF2", "id": "A0A140LHF2" }, { "name": "Gm1113", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A0A140LHF2", "id": "A0A140LHF2" } ], "protein_names": [ { "name": "V-set and immunoglobulin domain-containing protein 10-like 2", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "A0A140LHF2" } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A0A140LHF2", "url": "https://www.uniprot.org/uniprot/A0A140LHF2" } ], "common_name": "Mouse" } ], "gene": [ { "name": "Vsig10l2", "url": "https://www.uniprot.org/uniprot/A0A140LHF2", "locus": { "chromosome": "9", "start_pos": 35420518, "end_pos": 35429565, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSMUSG00000098590", "url": "https://www.ensembl.org/id/ENSMUSG00000098590" } ] } } ], "crossref": [ { "id": "ENSMUSG00000098590", "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000098590", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00096", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00096", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "2685959", "url": "http://www.informatics.jax.org/marker/MGI:2685959", "database": "MGI", "categories": [ "Organism-specific" ] }, { "id": "DPVNRTH", "url": "https://omabrowser.org/oma/group/DPVNRTH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR11640", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11640", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11640:SF150", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11640:SF150", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13927", "url": "http://pfam.xfam.org/family/PF13927", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PR_A0A140LHF2", "url": "http://purl.obolibrary.org/obo/PR_A0A140LHF2", "database": "PRO", "categories": [ "Protein" ] }, { "id": "A0A140LHF2", "url": "https://www.uniprot.org/uniprot/A0A140LHF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A140LHF2-1", "url": "https://www.uniprot.org/uniprot/A0A140LHF2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVGLSAHHRPLGCRLLILFCLLHPGASGQPYPTSNTAGEEALSVQGVRGSSVELECRTGPAPMAVLWSFTPLGSLVLQPVAVTSGASSKVESGALALGVVSLRNSSLVIEELREGARGHFLCQTLLVSGGQVHTAYLYLMLTVLVPVSKPRVQLNDPSPVEGVSVVATCAVREGTEPLTFSWHHHMPQGPGEVLVGLSEPRLQLDPVNRTHLGWYTCSVSNVVNQLKSDGAFLDVIYGPDKPVITVEPLGFSEDGFWASEREEVTLSCLAASNPPSHYVWFRDDSQIHTGPTYIIASASRTHTGLYTCLAHNRHLDTHTQTTVQLIIYYPPEGQPSCAVLPTLGVVTLLCTWPGGFPNAQLHWEGPQGIGPSASGNVTWSYTTTGLPNGSIFSCTGQHPTLAMPIFCRVTLWEPPGSPTCWTTATVGDQYIMLSCEWPGGEPPAMLSWLDRQQSLGDLGSSQAVHLLQAQSDLAGREFTCQGSHPLTAPGSHCRLRLEVPQLTVAEPRVSVLEGEEAWLGCALQRGTPPAQLLWLGPQQQQLEGSTPGFILHPEGTHLRLQVRDADPAHHRGTYQCVARNALGNSSQSVLLEVLSECKGFVCPCGYPTPPNVTISRLTYRRQRREVQLQWAIYGPGNLTGFLVQQRASVPSSEAGAWEVAASDIEPESRDRRLGGLDPGVLYAFRILAMNHHTAGYPSEVKTPVDPAFSAYPAVLGAAGTGVVVALATSLLVFQYAARHPHTFPCTETASTTSSSDPIQESIDAPVNVTITVTATP", "length": 776, "header": "sp|A0A140LHF2-1|VSXL2_MOUSE Isoform 1 of V-set and immunoglobulin domain-containing protein 10-like 2 OS=Mus musculus OX=10090 GN=Vsig10l2 PE=3 SV=2 CANONICAL=A0A140LHF2-1" }, "isoforms": [ { "isoform_ac": "A0A140LHF2-1", "url": "", "sequence": { "sequence": "MVGLSAHHRPLGCRLLILFCLLHPGASGQPYPTSNTAGEEALSVQGVRGSSVELECRTGPAPMAVLWSFTPLGSLVLQPVAVTSGASSKVESGALALGVVSLRNSSLVIEELREGARGHFLCQTLLVSGGQVHTAYLYLMLTVLVPVSKPRVQLNDPSPVEGVSVVATCAVREGTEPLTFSWHHHMPQGPGEVLVGLSEPRLQLDPVNRTHLGWYTCSVSNVVNQLKSDGAFLDVIYGPDKPVITVEPLGFSEDGFWASEREEVTLSCLAASNPPSHYVWFRDDSQIHTGPTYIIASASRTHTGLYTCLAHNRHLDTHTQTTVQLIIYYPPEGQPSCAVLPTLGVVTLLCTWPGGFPNAQLHWEGPQGIGPSASGNVTWSYTTTGLPNGSIFSCTGQHPTLAMPIFCRVTLWEPPGSPTCWTTATVGDQYIMLSCEWPGGEPPAMLSWLDRQQSLGDLGSSQAVHLLQAQSDLAGREFTCQGSHPLTAPGSHCRLRLEVPQLTVAEPRVSVLEGEEAWLGCALQRGTPPAQLLWLGPQQQQLEGSTPGFILHPEGTHLRLQVRDADPAHHRGTYQCVARNALGNSSQSVLLEVLSECKGFVCPCGYPTPPNVTISRLTYRRQRREVQLQWAIYGPGNLTGFLVQQRASVPSSEAGAWEVAASDIEPESRDRRLGGLDPGVLYAFRILAMNHHTAGYPSEVKTPVDPAFSAYPAVLGAAGTGVVVALATSLLVFQYAARHPHTFPCTETASTTSSSDPIQESIDAPVNVTITVTATP", "length": 776, "header": "sp|A0A140LHF2-1|VSXL2_MOUSE Isoform 1 of V-set and immunoglobulin domain-containing protein 10-like 2 OS=Mus musculus OX=10090 GN=Vsig10l2 PE=3 SV=2 CANONICAL=A0A140LHF2-1" }, "locus": { "chromosome": "9", "start_pos": 35429462, "end_pos": 35420521, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000183573", "url": "https://www.ensembl.org/id/ENSMUST00000183573" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000146390", "url": "https://www.ensembl.org/id/ENSMUSP00000146390" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "predicted", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 611, "start_aa": "Asn", "end_pos": 611, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn611", "evidence": [ { "id": "A0A140LHF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A140LHF2#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "predicted", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 637, "start_aa": "Asn", "end_pos": 637, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn637", "evidence": [ { "id": "A0A140LHF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/A0A140LHF2#ptm_processing" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "P0DP72-1", "protein_name": "V-set and immunoglobulin domain-containing protein 10-like 2", "gene_name": "VSIG10L2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVGQRAQHSPVSLLLLIHLCLLHLRASGQPHPTPEAPVEEVVSVQGVRGGSVELACGSGPAPLLVLWSFTPLGSLVPRPVAVTDGAMSKVEAIASALGVVSLRNSSLVLGELHEGARGHFLCQVLHVAGGQLHAAYSHLTLAVLVPVSKPQVRLSNPSPVEGASVVATCAVREGTEPVTFAWQHRAPRGLGEALVGVTEPLFQLDPVNRTHLGWYMCSASNSVNRLSSDGAFLDVIYGPDKPVITMEPLGLTEEGFWASEREEVTLSCLAASNPPSHYVWLRDHTQVHTGPTYVIARAGRVHTGLYTCLARNSYLDTRTQTTVQLTIYYPPEGQPSCAVHPSPEAVTLLCAWPGGLPPAQLQWEGPQGPGPTAPSNVTWSHAAAQLPSGSVFTCTGQHPALAPPALCTVMLWEPLGRPTCWSTATMGDQFIMLSCEWPGGEPPATLGWLDEQQQPLGGSSSSMAVHLLQAQEDLAGREFTCRGTHLLRTPDPHCHLQLEAPQLDVAEPRVSVLEGGEAWLECSLRGGTPPAQLLWLGPQQQKVDPGTSGFMLHPEGAQLRLGIYDADPAHHRGTYQCVARNAVGNSSQSVLLEVLRYPAPPNVTISRLTYGRHRREVQLQWAILGPGNLTGFLVQRKASALGPGAGAWETAASDIEPESRGRRLGGLDPGVLYAFRILALNHHTAGHPSEVKIPADPPFSAYPAVLGAAGTGMVVATVASLLVFQYAARHPETFPRLETPTTTPGLDPAQETTDSPVNVTITVTATP", "length": 767 }, "evidence": [ { "id": "A0A140LHF2", "url": "https://omabrowser.org/oma/group/A0A140LHF2/", "database": "OMA" } ], "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "A0A140LHF2", "url": "https://www.uniprot.org/uniprot/A0A140LHF2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A140LHF2", "url": "https://www.uniprot.org/uniprot/A0A140LHF2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "A0A140LHF2", "url": "https://www.uniprot.org/uniprot/A0A140LHF2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "A0A140LHF2", "url": "https://www.uniprot.org/uniprot/A0A140LHF2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 104, "end_pos": 106, "annotation": "n_glycosylation_sequon" }, { "start_pos": 208, "end_pos": 210, "annotation": "n_glycosylation_sequon" }, { "start_pos": 376, "end_pos": 378, "annotation": "n_glycosylation_sequon" }, { "start_pos": 388, "end_pos": 390, "annotation": "n_glycosylation_sequon" }, { "start_pos": 584, "end_pos": 586, "annotation": "n_glycosylation_sequon" }, { "start_pos": 611, "end_pos": 613, "annotation": "n_glycosylation_sequon" }, { "start_pos": 637, "end_pos": 639, "annotation": "n_glycosylation_sequon" }, { "start_pos": 767, "end_pos": 769, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "synthesized_glycans": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 2 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 2 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }