{
    "uniprot_canonical_ac": "A0A126GUQ2-1",
    "uniprot_ac": "A0A126GUQ2",
    "uniprot_id": "A0A126GUQ2_DROME",
    "mass": {
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        "monoisotopic_mass": 273878.0
    },
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        "ac": "NP_001303493",
        "name": "Piezo-like",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001303493"
    },
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            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A126GUQ2",
            "id": "A0A126GUQ2"
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            "resource": "RefSeq",
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            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001303493",
            "id": "NP_001303493"
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            "resource": "UniProtKB",
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            "url": "https://www.uniprot.org/uniprot/A0A126GUQ2",
            "id": "A0A126GUQ2"
        },
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            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A126GUQ2",
            "id": "A0A126GUQ2"
        },
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            "name": "CG40249",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A126GUQ2",
            "id": "A0A126GUQ2"
        },
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            "url": "https://www.uniprot.org/uniprot/A0A126GUQ2",
            "id": "A0A126GUQ2"
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            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A126GUQ2",
            "id": "A0A126GUQ2"
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            "url": "https://www.uniprot.org/uniprot/A0A126GUQ2",
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            "url": "https://www.uniprot.org/uniprot/A0A126GUQ2",
            "id": "A0A126GUQ2"
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            "name": "CG42617",
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            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A126GUQ2",
            "id": "A0A126GUQ2"
        },
        {
            "name": "CG42618",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A126GUQ2",
            "id": "A0A126GUQ2"
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            "name": "CG45783",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A126GUQ2",
            "id": "A0A126GUQ2"
        },
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            "name": "CR41056",
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            "url": "https://www.uniprot.org/uniprot/A0A126GUQ2",
            "id": "A0A126GUQ2"
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        {
            "name": "Dmel\\CG45783",
            "resource": "UniProtKB",
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            "url": "https://www.uniprot.org/uniprot/A0A126GUQ2",
            "id": "A0A126GUQ2"
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            "url": "https://www.uniprot.org/uniprot/A0A126GUQ2",
            "id": "A0A126GUQ2"
        },
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            "name": "Pzl",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001303493",
            "id": "NP_001303493"
        }
    ],
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        {
            "name": "Piezo-type mechanosensitive ion channel component",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "A0A126GUQ2"
        },
        {
            "name": "CG45783-PE; Pzl-PE",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001303493",
            "id": "NP_001303493"
        },
        {
            "name": "Piezo-like",
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            "id": "NP_001303493"
        }
    ],
    "function": [],
    "disease": [
        {
            "disease_id": "DOID:0050580",
            "recommended_name": {
                "id": "DOID:0050580",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0050580",
                "name": "hereditary lymphedema",
                "description": "A lymphedema commonly located_in legs, caused_by congenital abnormalities in the lymphatic system."
            },
            "synonyms": [
                {
                    "id": "MONDO:0007919",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007919",
                    "name": "lymphatic malformation 1",
                    "description": "Any hereditary lymphedema in which the cause of the disease is a mutation in the FLT4 gene."
                },
                {
                    "id": "MONDO:0007919",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007919",
                    "name": "FLT4 hereditary lymphedema",
                    "description": ""
                },
                {
                    "id": "MONDO:0007919",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007919",
                    "name": "LMPH1A",
                    "description": ""
                },
                {
                    "id": "MONDO:0007919",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007919",
                    "name": "Milroy disease",
                    "description": ""
                },
                {
                    "id": "MONDO:0007919",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007919",
                    "name": "Nonne-Milroy disease",
                    "description": ""
                },
                {
                    "id": "MONDO:0007919",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007919",
                    "name": "Nonne-Milroy lymphedema",
                    "description": ""
                },
                {
                    "id": "MONDO:0007919",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007919",
                    "name": "Nonne-Milroy syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0007919",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007919",
                    "name": "Nonnes syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0007919",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007919",
                    "name": "congenital hereditary lymphedema",
                    "description": ""
                },
                {
                    "id": "MONDO:0007919",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007919",
                    "name": "congenital primary lymphedema",
                    "description": ""
                },
                {
                    "id": "MONDO:0007919",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007919",
                    "name": "early onset lymphedema",
                    "description": ""
                },
                {
                    "id": "MONDO:0007919",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007919",
                    "name": "hereditary lymphedema 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0007919",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007919",
                    "name": "hereditary lymphedema caused by mutation in FLT4",
                    "description": ""
                },
                {
                    "id": "MONDO:0007919",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007919",
                    "name": "hereditary lymphedema type I",
                    "description": ""
                },
                {
                    "id": "MONDO:0007919",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007919",
                    "name": "lymphedema, early-onset",
                    "description": ""
                },
                {
                    "id": "MONDO:0007919",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007919",
                    "name": "lymphedema, hereditary, 1A",
                    "description": ""
                },
                {
                    "id": "MONDO:0007919",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007919",
                    "name": "lymphedema, hereditary, type 1A",
                    "description": ""
                },
                {
                    "id": "MONDO:0007919",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007919",
                    "name": "primary congenital lymphedema",
                    "description": ""
                },
                {
                    "id": "MIM:153100",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/153100",
                    "name": "Lymphatic malformation 1",
                    "description": "Lymphatic malformation 1"
                }
            ],
            "evidence": [
                {
                    "id": "0050580",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050580"
                }
            ]
        },
        {
            "disease_id": "DOID:0111576",
            "recommended_name": {
                "id": "DOID:0111576",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0111576",
                "name": "dehydrated hereditary stomatocytosis 1",
                "description": "A dehydrated hereditary stomatocytosis that has_material_basis_in heterozygous mutation in the PIEZO1 gene on chromosome 16q24.3."
            },
            "synonyms": [
                {
                    "id": "DOID:0111576",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0111576",
                    "name": "dehydrated hereditary stomatocytosis 1 with or without pseudohyperkalemia and/or perinatal edema",
                    "description": ""
                },
                {
                    "id": "DOID:0111576",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0111576",
                    "name": "PSHK1",
                    "description": ""
                },
                {
                    "id": "DOID:0111576",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0111576",
                    "name": "pseudohyperkalemia familial 1, due to red cell leak",
                    "description": ""
                },
                {
                    "id": "DOID:0111576",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0111576",
                    "name": "pseudohyperkalemia edinburgh",
                    "description": ""
                },
                {
                    "id": "MONDO:0008689",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008689",
                    "name": "dehydrated hereditary stomatocytosis with or without pseudohyperkalemia and/or perinatal edema",
                    "description": ""
                },
                {
                    "id": "MONDO:0008689",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008689",
                    "name": "dehydrated hereditary stomatocytosis with or without pseudohyperkalemia and/or perinatal edema",
                    "description": ""
                },
                {
                    "id": "MONDO:0008689",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008689",
                    "name": "DEHYDRATED hereditary stomatocytosis 1 with or without pseudohyperkalemia and/OR perinatal edema",
                    "description": ""
                },
                {
                    "id": "MONDO:0008689",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008689",
                    "name": "DEHYDRATED hereditary stomatocytosis 1 with or without pseudohyperkalemia and/OR perinatal oedema",
                    "description": ""
                },
                {
                    "id": "MONDO:0008689",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008689",
                    "name": "DEHYDRATED hereditary stomatocytosis with or without pseudohyperkalemia and/or perinatal edema",
                    "description": ""
                },
                {
                    "id": "MONDO:0008689",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008689",
                    "name": "DEHYDRATED hereditary stomatocytosis with or without pseudohyperkalemia and/or perinatal oedema",
                    "description": ""
                },
                {
                    "id": "MONDO:0008689",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008689",
                    "name": "DHS",
                    "description": ""
                },
                {
                    "id": "MONDO:0008689",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008689",
                    "name": "DHS1",
                    "description": ""
                },
                {
                    "id": "MONDO:0008689",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008689",
                    "name": "Dehydrated hereditary stomatocytosis 1 with or without pseudohyperkalemia and/Or perinatal edema",
                    "description": ""
                },
                {
                    "id": "MONDO:0008689",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008689",
                    "name": "Dehydrated hereditary stomatocytosis 1 with or without pseudohyperkalemia and/Or perinatal oedema",
                    "description": ""
                },
                {
                    "id": "MONDO:0008689",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008689",
                    "name": "Dehydrated hereditary stomatocytosis pseudohyperkalemia and perinatal edema",
                    "description": ""
                },
                {
                    "id": "MONDO:0008689",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008689",
                    "name": "Dehydrated hereditary stomatocytosis pseudohyperkalemia and perinatal oedema",
                    "description": ""
                },
                {
                    "id": "MONDO:0008689",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008689",
                    "name": "Desiccytosis, hereditary",
                    "description": ""
                },
                {
                    "id": "MONDO:0008689",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008689",
                    "name": "dehydrated hereditary stomatocytosis",
                    "description": ""
                },
                {
                    "id": "MONDO:0008689",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008689",
                    "name": "pseudohyperkalemia Edinburgh",
                    "description": ""
                },
                {
                    "id": "MONDO:0008689",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008689",
                    "name": "pseudohyperkalemia, familial, 1, due to Red cell leak",
                    "description": ""
                },
                {
                    "id": "MONDO:0008689",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008689",
                    "name": "xerocytosis, hereditary",
                    "description": ""
                },
                {
                    "id": "MIM:194380",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/194380",
                    "name": "Dehydrated hereditary stomatocytosis 1 with or without pseudohyperkalemia and/or perinatal edema",
                    "description": "Dehydrated hereditary stomatocytosis 1 with or without pseudohyperkalemia and/or perinatal edema"
                }
            ],
            "evidence": [
                {
                    "id": "0111576",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0111576"
                }
            ]
        },
        {
            "disease_id": "DOID:0111607",
            "recommended_name": {
                "id": "DOID:0111607",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0111607",
                "name": "distal arthrogryposis type 3",
                "description": "A distal arthrogryposis characterized by distal arthrogryposis with short stature and cleft palate that has_material_basis_in heterozygous mutation in the PIEZO2 gene on chromosome 18p11.22-p11.21."
            },
            "synonyms": [
                {
                    "id": "DOID:0111607",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0111607",
                    "name": "DA3",
                    "description": ""
                },
                {
                    "id": "DOID:0111607",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0111607",
                    "name": "Gordon syndrome",
                    "description": ""
                },
                {
                    "id": "DOID:0111607",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0111607",
                    "name": "camptodactyly-cleft palate-clubfoot syndrome",
                    "description": ""
                },
                {
                    "id": "DOID:0111607",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0111607",
                    "name": "distal arthrogryposis multiplex congenita type IIA",
                    "description": ""
                },
                {
                    "id": "MONDO:0007252",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007252",
                    "name": "Gordon syndrome",
                    "description": "An extremely rare multiple congenital malformation syndrome characterized by congenital contractures of hand and feet with variable degrees of severity of camptodactyly, clubfoot and, less frequently, cleft palate. Intelligence is normal but in some cases, additional abnormalities, such as short stature, kyphoscoliosis, ptosis, micrognathia, and cryptorchidism may also be present. Gordon syndrome, Marden-Walker syndrome and arthrogryposis with oculomotor limitation and electroretinal anomalies clinically and genetically overlap, and could represent variable expressions of the same condition."
                },
                {
                    "id": "MONDO:0007252",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007252",
                    "name": "Gordon syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0007252",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007252",
                    "name": "camptodactyly-cleft palate-clubfoot syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0007252",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007252",
                    "name": "distal arthrogryposis type 3",
                    "description": ""
                },
                {
                    "id": "MONDO:0007252",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007252",
                    "name": "distal arthrogryposis type IIA",
                    "description": ""
                },
                {
                    "id": "MONDO:0007252",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007252",
                    "name": "DA3",
                    "description": ""
                },
                {
                    "id": "MONDO:0007252",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007252",
                    "name": "arthrogryposis distal type 3",
                    "description": ""
                },
                {
                    "id": "MONDO:0007252",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007252",
                    "name": "arthrogryposis multiplex congenita, distal, type 2A",
                    "description": ""
                },
                {
                    "id": "MONDO:0007252",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007252",
                    "name": "arthrogryposis, distal, type 3",
                    "description": ""
                },
                {
                    "id": "MONDO:0007252",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007252",
                    "name": "camptodactyly, cleft palate, and clubfoot",
                    "description": ""
                },
                {
                    "id": "MIM:114300",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/114300",
                    "name": "Arthrogryposis, distal, 3",
                    "description": "Arthrogryposis, distal, 3"
                }
            ],
            "evidence": [
                {
                    "id": "0111607",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0111607"
                }
            ]
        },
        {
            "disease_id": "DOID:0111608",
            "recommended_name": {
                "id": "DOID:0111608",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0111608",
                "name": "distal arthrogryposis type 5",
                "description": "A distal arthrogryposis characterized by distal arthrogryposis with ocular abnormalities that has_material_basis_in heterozygous gain of function mutation in the PIEZO2 gene on chromosome 18p11.22-p11.21."
            },
            "synonyms": [
                {
                    "id": "DOID:0111608",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0111608",
                    "name": "arthrogryposis-oculomotor limitation-electroretinal anomalies syndrome",
                    "description": ""
                },
                {
                    "id": "DOID:0111608",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0111608",
                    "name": "DA5",
                    "description": ""
                },
                {
                    "id": "DOID:0111608",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0111608",
                    "name": "DAIIB",
                    "description": ""
                },
                {
                    "id": "DOID:0111608",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0111608",
                    "name": "distal arthrogryposis type IIB",
                    "description": ""
                },
                {
                    "id": "DOID:0111608",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0111608",
                    "name": "distal arthrogryposis with ophthalmoplegia",
                    "description": ""
                },
                {
                    "id": "DOID:0111608",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0111608",
                    "name": "oculomelic amyoplasia",
                    "description": ""
                },
                {
                    "id": "MONDO:0007158",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007158",
                    "name": "arthrogryposis- oculomotor limitation-electroretinal anomalies syndrome",
                    "description": "Distal arthrogryposis type 5 is an inherited developmental defect syndrome characterized by multiple congenital contractures of limbs, without primary neurologic and/or muscle disease that affects limb function, and ocular anomalies (ptosis, external ophtalmoplegia and/or strabismus). Intelligence is normal."
                },
                {
                    "id": "MONDO:0007158",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007158",
                    "name": "arthrogryposis- oculomotor limitation-electroretinal anomalies syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0007158",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007158",
                    "name": "distal arthrogryposis type 5",
                    "description": ""
                },
                {
                    "id": "MONDO:0007158",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007158",
                    "name": "distal arthrogryposis type IIB",
                    "description": ""
                },
                {
                    "id": "MONDO:0007158",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007158",
                    "name": "distal arthrogryposis with ophthalmoplegia",
                    "description": ""
                },
                {
                    "id": "MONDO:0007158",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007158",
                    "name": "oculomelic amyoplasia",
                    "description": ""
                },
                {
                    "id": "MONDO:0007158",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007158",
                    "name": "Arthogryposis with oculomotor limitation and electroretinal abnormalities",
                    "description": ""
                },
                {
                    "id": "MONDO:0007158",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007158",
                    "name": "DA5",
                    "description": ""
                },
                {
                    "id": "MONDO:0007158",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007158",
                    "name": "arthrogryposis ophthalmoplegia retinopathy",
                    "description": ""
                },
                {
                    "id": "MONDO:0007158",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007158",
                    "name": "arthrogryposis with oculomotor limitation and electroretinal abnormalities",
                    "description": ""
                },
                {
                    "id": "MONDO:0007158",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007158",
                    "name": "arthrogryposis, distal, type 2B",
                    "description": ""
                },
                {
                    "id": "MONDO:0007158",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007158",
                    "name": "arthrogryposis, distal, type 5",
                    "description": ""
                },
                {
                    "id": "MONDO:0007158",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007158",
                    "name": "arthrogryposis-oculomotor limitation-electroretinal anomalies syndrome",
                    "description": ""
                },
                {
                    "id": "MIM:108145",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/108145",
                    "name": "Arthrogryposis, distal, 5",
                    "description": "Arthrogryposis, distal, 5"
                }
            ],
            "evidence": [
                {
                    "id": "0111608",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0111608"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Drosophila melanogaster",
            "taxid": 7227,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A126GUQ2",
                    "url": "https://www.uniprot.org/uniprot/A0A126GUQ2"
                }
            ],
            "common_name": "Fruit fly"
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    ],
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            "url": "https://www.uniprot.org/uniprot/A0A126GUQ2",
            "locus": {
                "chromosome": "3R",
                "start_pos": 2554162,
                "end_pos": 3263582,
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                        "url": "https://www.ensembl.org/id/FBgn0267430"
                    }
                ]
            }
        }
    ],
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        {
            "id": "FBgn0267430",
            "url": "https://bgee.org/?page=gene&gene_id=FBgn0267430",
            "database": "Bgee",
            "categories": [
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            ]
        },
        {
            "id": "FBgn0267430",
            "url": "https://flybase.org/reports/FBgn0267430",
            "database": "FlyBase",
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            ]
        },
        {
            "id": "26067051",
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            "database": "GeneID",
            "categories": [
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            ]
        },
        {
            "id": "IPR027272",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR027272",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR031334",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR031334",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR031805",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR031805",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "dme:Dmel_CG45783",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+dme:Dmel_CG45783",
            "database": "KEGG Pathway",
            "categories": [
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            ]
        },
        {
            "id": "ITHKQST",
            "url": "https://omabrowser.org/oma/group/ITHKQST/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "5491808at2759",
            "url": "http://www.orthodb.org/?query=5491808at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR13167",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13167",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR13167:SF25",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13167:SF25",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF12166",
            "url": "http://pfam.xfam.org/family/PF12166",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF15917",
            "url": "http://pfam.xfam.org/family/PF15917",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "NP_001303493",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001303493",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A126GUQ2",
            "url": "https://www.uniprot.org/uniprot/A0A126GUQ2",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A126GUQ2-1",
            "url": "https://www.uniprot.org/uniprot/A0A126GUQ2-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MAEPLLFIITRIFLPLTLILVSLVRPVGLSYFYLLTFFLSPWLLQSNSLKQRTFLNVFIIFLCVLSTFGIVGHIIFNLINLFFVDLSSKNSFSFILRQFGFLYFKGLSFVSIAHWILPDIIVLLNTIVFFIFSEIKYKREKRVIQNDDDVFYKKSKELKGALKVAEINRVLIIVYIRSVLKTSLIFSLIVLYFAATLRPSLPGSLYFCMFIIAGSYWALFRQRKMYYSVIFMIVALLVHITCIFAYQLPVLQNTINCDKLWTRLMGMEVLIRLNKDNRNGKILELNPKLNLDSYLSPIALMLAYFATTLSLINRSQYEISFNTIRMNLGPKSNSIYDNIQPSNEENEEISIFTEPSMLEQFFYIVYELSSFVYKNSYILLNIIMMIWSIVYHSWLTFVLLIWANILWMIPNQRRSMMRSSLFVVFYSQILLLAQYIYGMNLYESELPTKVTSCGLNLEQIGFVHPQSKDSLPWIPLTVKTVFLFVFWVTSRQYFREISLDRQQSDLLQQIFATHRSRSEHLLSKKSQTPQIFIYILKSTSHFITRIWMWLLIFLIFLCAMIDRTMTGIRICYMSLFLLFLMVFQMSLQLWIRFLYGYWIFLIFYAMTILTAIYTYQFDHFDYYWEKFLKVHSTLQCDIGLRRYQTKDLFLHLLIPTLTVIFTVVQLHYFHRRFVESVRRPRSTEGQNFHLAPNAETRASQKTLDIHRQSWKVFFDAGYENVRAKGRQLFNPGKIVAWKFLEMHMIKTVTLASFYCAISEICFLNLFLVILSLLGICGNRFLRRVIFRAVTFWISLLVLMKMIYQIKYLDQSHYNFKCGNVTVNFAEWMGLRKTGTVFGVHLRYISSYIIYMILTSLHAVVKLRDHLIRYSTHKQKDTKLLFPDITRQDAERDFPGLLKYVLNYGYFKFGFEITMIGLMSTIAHRRDLFALTYLIWLVLLLCLSRFRCARIWEMLQLYFVLSIFVQYVYLLNFPPNLCNVISYNSLWSISGSKNYTNRSNIMFDYIVLLLISRQRKSFRVEMRHINDLSYRGGVNTNVVHNIAKLGHVYFENPTHDFCTYVRNYADVLKTAIFFSFFWITLAIVFLGGVCSTDILSLGYIIFALIFLLQGSEIYLQNIHFIICRWNCLIAFNIFNIIVKVAIIVLEGTINLEHKSILSIVFNVMHQTAPCENIMDGKFFEINEISEKKYCYGPSDMIFKNTLVWHAIIFSFVVFQYRIFGSYYFCHVIMDTQANTILASRGAAIIENLHYKQIYDRRKNEQSVLERVKMKMERIRITNRRHQKQATGLDFQPHKPPSSIIHVHYRAEEKSKLKTLNNEFLTTIKQAERDTYFSRSLKPRRRDLSLHPHAVRTGDYYMFNELDDDDDLDVYEEYDFLEKEDVRARQMRQSLRSRASNYNRSKSFLNDENSDTDTKKLETHPVIILTSELIVLLTFRLNRLSKNFRFVHKMLSAEKKKLQNISIMNRLGLSNTAAMFKFLNKSLNNKVIKEAGSYYVSQDNDFTTLDHNDFVQMLIALWYALIANTETICYLVVFLNQAANSSVISLPMPFLVLCWGALTLPRPSKTFWVTLITYNLTMIFVKSIMHQRVLLDQQLVSRSNSLSFELIMKRGRAVYDLLLLVVLFWHQYMLKKQGIWTIQRTNSELLLLEKKRNHYKRSFSKERPENIRKLLREEGGGEQVKAVRPNAIEFKREMDDILLPALENKYVYQNIESEYYRKAMQGLANKGGLLSGFRKFFLALRHKSRLSTDVYTLLFLCDFISFFILLFGFPKFVYRYKYSTSVLETYIQGNKVPFTFLLMLIVQFITIVTERAIYLRKALIYKIFFHFISVLGIHIWMFFLVPYITSHSFGETAPVLFYLIKCLHMLLSAYQIRCGYPKRILGNVFTKGYSLANYIAFKIYMEIPFLYILRTMLDWVCIDTTLTVMEWIKMEDIFQSVFIVRCYRQMDTDFPVLRGEPKALYSKLLIGGTIILILIALIWSPLFLFALVGTVGKPNIPQKADITVKINHYEPIYVSQSNSDILQFSNSDFQKLTNHIILDNYASDSMMLYDAVDVTAIKFYENSISLWNMPPPDKERLLHDLSNGETLDIHLTLTLKCNLTPEAVIYETTYTLTENKVHTRDKLIRLMSNNFSNEKVIIPNILPKFITVQRQQANAKFIKDYDGKFNRPIILTKIGKSQVYWWEMNDYCNDRFYTEILSALPLSNCENGVVLYVFNDKSFPSAMSFLEKTGIIGLYTTFVYVVSRIIRSLIANNHRRIMFEDLPYVDRVLKLCTDIYLVRETQEYRLEEDLYGKLIFLYRSPETLIKWTRFKEDISETASNSQLSIQRN",
        "length": 2326,
        "header": "tr|A0A126GUQ2-1|A0A126GUQ2_DROME Isoform 1 of Piezo-type mechanosensitive ion channel component  OS=Drosophila melanogaster OX=7227 GN=Pzl PE=3 SV=1 CANONICAL=A0A126GUQ2-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A126GUQ2-1",
            "url": "",
            "sequence": {
                "sequence": "MAEPLLFIITRIFLPLTLILVSLVRPVGLSYFYLLTFFLSPWLLQSNSLKQRTFLNVFIIFLCVLSTFGIVGHIIFNLINLFFVDLSSKNSFSFILRQFGFLYFKGLSFVSIAHWILPDIIVLLNTIVFFIFSEIKYKREKRVIQNDDDVFYKKSKELKGALKVAEINRVLIIVYIRSVLKTSLIFSLIVLYFAATLRPSLPGSLYFCMFIIAGSYWALFRQRKMYYSVIFMIVALLVHITCIFAYQLPVLQNTINCDKLWTRLMGMEVLIRLNKDNRNGKILELNPKLNLDSYLSPIALMLAYFATTLSLINRSQYEISFNTIRMNLGPKSNSIYDNIQPSNEENEEISIFTEPSMLEQFFYIVYELSSFVYKNSYILLNIIMMIWSIVYHSWLTFVLLIWANILWMIPNQRRSMMRSSLFVVFYSQILLLAQYIYGMNLYESELPTKVTSCGLNLEQIGFVHPQSKDSLPWIPLTVKTVFLFVFWVTSRQYFREISLDRQQSDLLQQIFATHRSRSEHLLSKKSQTPQIFIYILKSTSHFITRIWMWLLIFLIFLCAMIDRTMTGIRICYMSLFLLFLMVFQMSLQLWIRFLYGYWIFLIFYAMTILTAIYTYQFDHFDYYWEKFLKVHSTLQCDIGLRRYQTKDLFLHLLIPTLTVIFTVVQLHYFHRRFVESVRRPRSTEGQNFHLAPNAETRASQKTLDIHRQSWKVFFDAGYENVRAKGRQLFNPGKIVAWKFLEMHMIKTVTLASFYCAISEICFLNLFLVILSLLGICGNRFLRRVIFRAVTFWISLLVLMKMIYQIKYLDQSHYNFKCGNVTVNFAEWMGLRKTGTVFGVHLRYISSYIIYMILTSLHAVVKLRDHLIRYSTHKQKDTKLLFPDITRQDAERDFPGLLKYVLNYGYFKFGFEITMIGLMSTIAHRRDLFALTYLIWLVLLLCLSRFRCARIWEMLQLYFVLSIFVQYVYLLNFPPNLCNVISYNSLWSISGSKNYTNRSNIMFDYIVLLLISRQRKSFRVEMRHINDLSYRGGVNTNVVHNIAKLGHVYFENPTHDFCTYVRNYADVLKTAIFFSFFWITLAIVFLGGVCSTDILSLGYIIFALIFLLQGSEIYLQNIHFIICRWNCLIAFNIFNIIVKVAIIVLEGTINLEHKSILSIVFNVMHQTAPCENIMDGKFFEINEISEKKYCYGPSDMIFKNTLVWHAIIFSFVVFQYRIFGSYYFCHVIMDTQANTILASRGAAIIENLHYKQIYDRRKNEQSVLERVKMKMERIRITNRRHQKQATGLDFQPHKPPSSIIHVHYRAEEKSKLKTLNNEFLTTIKQAERDTYFSRSLKPRRRDLSLHPHAVRTGDYYMFNELDDDDDLDVYEEYDFLEKEDVRARQMRQSLRSRASNYNRSKSFLNDENSDTDTKKLETHPVIILTSELIVLLTFRLNRLSKNFRFVHKMLSAEKKKLQNISIMNRLGLSNTAAMFKFLNKSLNNKVIKEAGSYYVSQDNDFTTLDHNDFVQMLIALWYALIANTETICYLVVFLNQAANSSVISLPMPFLVLCWGALTLPRPSKTFWVTLITYNLTMIFVKSIMHQRVLLDQQLVSRSNSLSFELIMKRGRAVYDLLLLVVLFWHQYMLKKQGIWTIQRTNSELLLLEKKRNHYKRSFSKERPENIRKLLREEGGGEQVKAVRPNAIEFKREMDDILLPALENKYVYQNIESEYYRKAMQGLANKGGLLSGFRKFFLALRHKSRLSTDVYTLLFLCDFISFFILLFGFPKFVYRYKYSTSVLETYIQGNKVPFTFLLMLIVQFITIVTERAIYLRKALIYKIFFHFISVLGIHIWMFFLVPYITSHSFGETAPVLFYLIKCLHMLLSAYQIRCGYPKRILGNVFTKGYSLANYIAFKIYMEIPFLYILRTMLDWVCIDTTLTVMEWIKMEDIFQSVFIVRCYRQMDTDFPVLRGEPKALYSKLLIGGTIILILIALIWSPLFLFALVGTVGKPNIPQKADITVKINHYEPIYVSQSNSDILQFSNSDFQKLTNHIILDNYASDSMMLYDAVDVTAIKFYENSISLWNMPPPDKERLLHDLSNGETLDIHLTLTLKCNLTPEAVIYETTYTLTENKVHTRDKLIRLMSNNFSNEKVIIPNILPKFITVQRQQANAKFIKDYDGKFNRPIILTKIGKSQVYWWEMNDYCNDRFYTEILSALPLSNCENGVVLYVFNDKSFPSAMSFLEKTGIIGLYTTFVYVVSRIIRSLIANNHRRIMFEDLPYVDRVLKLCTDIYLVRETQEYRLEEDLYGKLIFLYRSPETLIKWTRFKEDISETASNSQLSIQRN",
                "length": 2326,
                "header": "tr|A0A126GUQ2-1|A0A126GUQ2_DROME Isoform 1 of Piezo-type mechanosensitive ion channel component  OS=Drosophila melanogaster OX=7227 GN=Pzl PE=3 SV=1 CANONICAL=A0A126GUQ2-1"
            },
            "locus": {
                "chromosome": "3R",
                "start_pos": 3263573,
                "end_pos": 2554163,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "FBtr0445191",
                        "url": "https://www.ensembl.org/id/FBtr0445191"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "FBpp0401450",
                        "url": "https://www.ensembl.org/id/FBpp0401450"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [
        {
            "id": "dme:Dmel_CG45783",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+dme:Dmel_CG45783",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [],
    "go_annotation": {
        "categories": [
            {
                "name": "Biological Process",
                "total": 4,
                "go_terms": [
                    {
                        "name": "mechanosensory behavior",
                        "id": "GO:0007638",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007638",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A126GUQ2",
                                "url": "https://www.uniprot.org/uniprot/A0A126GUQ2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "regulation of membrane potential",
                        "id": "GO:0042391",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042391",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A126GUQ2",
                                "url": "https://www.uniprot.org/uniprot/A0A126GUQ2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cellular response to mechanical stimulus",
                        "id": "GO:0071260",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071260",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A126GUQ2",
                                "url": "https://www.uniprot.org/uniprot/A0A126GUQ2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "detection of mechanical stimulus",
                        "id": "GO:0050982",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050982",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A126GUQ2",
                                "url": "https://www.uniprot.org/uniprot/A0A126GUQ2"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 1,
                "go_terms": [
                    {
                        "name": "plasma membrane",
                        "id": "GO:0005886",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A126GUQ2",
                                "url": "https://www.uniprot.org/uniprot/A0A126GUQ2"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 2,
                "go_terms": [
                    {
                        "name": "monoatomic cation channel activity",
                        "id": "GO:0005261",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005261",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A126GUQ2",
                                "url": "https://www.uniprot.org/uniprot/A0A126GUQ2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "mechanosensitive monoatomic ion channel activity",
                        "id": "GO:0008381",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008381",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A126GUQ2",
                                "url": "https://www.uniprot.org/uniprot/A0A126GUQ2"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 1397,
            "end_pos": 1399,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 1458,
            "end_pos": 1460,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 1478,
            "end_pos": 1480,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 1538,
            "end_pos": 1540,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 1573,
            "end_pos": 1575,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 2096,
            "end_pos": 2098,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 2128,
            "end_pos": 2130,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 313,
            "end_pos": 315,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 819,
            "end_pos": 821,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 993,
            "end_pos": 995,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 996,
            "end_pos": 998,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [],
    "section_stats": [
        {
            "table_id": "glycosylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
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