{ "uniprot_canonical_ac": "A0A0G2KAF4-1", "uniprot_ac": "A0A0G2KAF4", "uniprot_id": "A0A0G2KAF4_RAT", "mass": { "chemical_mass": 102364.0, "monoisotopic_mass": 102364.0 }, "refseq": {}, "gene_names": [ { "name": "Nfxl1", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A0A0G2KAF4", "id": "A0A0G2KAF4" } ], "protein_names": [ { "name": "Nuclear transcription factor, X-box binding-like 1", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "A0A0G2KAF4" } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KAF4", "url": "https://www.uniprot.org/uniprot/A0A0G2KAF4" } ], "common_name": "Rat" } ], "gene": [ { "name": "Nfxl1", "url": "https://www.uniprot.org/uniprot/A0A0G2KAF4", "locus": { "chromosome": "14", "start_pos": 35667498, "end_pos": 35626066, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSRNOG00000058588", "url": "https://www.ensembl.org/id/ENSRNOG00000058588" } ] } } ], "crossref": [ { "id": "ENSRNOG00000058588", "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000058588", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06008", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06008", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16697", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16697", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000967", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000967", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034078", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034078", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "rno:289595", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:289595", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PCPPCAQ", "url": "https://omabrowser.org/oma/group/PCPPCAQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "1412at2759", "url": "http://www.orthodb.org/?query=1412at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12360", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12360", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12360:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12360:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01422", "url": "http://pfam.xfam.org/family/PF01422", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "1359201", "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1359201", "database": "RGD", "categories": [ "Organism-specific" ] }, { "id": "A0A0G2KAF4", "url": "https://www.uniprot.org/uniprot/A0A0G2KAF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0G2KAF4-1", "url": "https://www.uniprot.org/uniprot/A0A0G2KAF4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1LNF3", "url": "https://www.uniprot.org/uniprot/F1LNF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1LNF3-1", "url": "https://www.uniprot.org/uniprot/F1LNF3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDASWRQVAAGRGRARGRGTAVPLSGNGVPLSGAGGGRAKGSGGAVPSAPGPRRAATPGPAGHKQRSAGGEAPQPLWVGGEDGSGEDGSELISQRKFEEIKKANQAAARKLVEEHCSSSSEEEEGDEDFEGKQGKIVANTFITYTTHTDGDVHELEKTKQYLNEAFQAGAMTCLICIASVKRNQAVWSCSGCFCIFHMPCIQKWAKDSQFLVSSVTDDDFGKKDYPWPCPKCRFEYKRSETPSRYYCYCGKVEDPPLDPWLVPHSCGQVCEREFKPSCGHKCLLLCHPGPCPPCPKMVTTTCYCKKAKPIPRRCSAKQWSCQLPCGRKLLCGQHSCENPCHAGNCQPCPRVSRQKCVCGKKVAERSCASPVWHCDQVCRKTLPCGNHTCEQVCHVGACGECPRSGKRSCPCQKSKFSLPCTEDVPTCGDSCDKILECGIHRCSQRCHRGPCETCRQEVEKQCRCGKHTKRMPCHKTYLCETKCVKMRDCQKHQCRRKCCPGNCPPCDQNCGRTLGCRNHKCPSVCHRGSCYPCPETVDVKCNCGNAKVTVPCGRERTTRPPKCKELCSRPPTCHHSSQEKHRCHFGPCPPCHQPCQKVLEKCGHLCPISCHDQALVKQTGRHQLSGPWEQPAEPAFIQTALPCPPCQVPIPVECLGKHEVSPLPCHAVGPYSCKRLCGRMLNCQNHTCTKECHKVTEVDGCPGRHKAGPECLQCEEGCSKSRPAGCPHPCVLPCHPGKCPPCVQMLRIKCHCKITNLYVECRKITTADVSEKNLLSCCKNQCPKELPCGHRCKEMCHPGECPYNCNQKVKLRCPCKRIKRELPCNKIRGNQVSVECDAACKEMKRKASEIKEAEANAALEEEKRRQQAELEAFENRLKGRRKKNRKRDEVAVQLSPWQKYKSYLFPVCGVVVAVLVWYICHHAD", "length": 924, "header": "tr|A0A0G2KAF4-1|A0A0G2KAF4_RAT Isoform 1 of Nuclear transcription factor, X-box binding-like 1 OS=Rattus norvegicus OX=10116 GN=Nfxl1 PE=1 SV=1 CANONICAL=A0A0G2KAF4-1" }, "isoforms": [ { "isoform_ac": "A0A0G2KAF4-1", "url": "", "sequence": { "sequence": "MDASWRQVAAGRGRARGRGTAVPLSGNGVPLSGAGGGRAKGSGGAVPSAPGPRRAATPGPAGHKQRSAGGEAPQPLWVGGEDGSGEDGSELISQRKFEEIKKANQAAARKLVEEHCSSSSEEEEGDEDFEGKQGKIVANTFITYTTHTDGDVHELEKTKQYLNEAFQAGAMTCLICIASVKRNQAVWSCSGCFCIFHMPCIQKWAKDSQFLVSSVTDDDFGKKDYPWPCPKCRFEYKRSETPSRYYCYCGKVEDPPLDPWLVPHSCGQVCEREFKPSCGHKCLLLCHPGPCPPCPKMVTTTCYCKKAKPIPRRCSAKQWSCQLPCGRKLLCGQHSCENPCHAGNCQPCPRVSRQKCVCGKKVAERSCASPVWHCDQVCRKTLPCGNHTCEQVCHVGACGECPRSGKRSCPCQKSKFSLPCTEDVPTCGDSCDKILECGIHRCSQRCHRGPCETCRQEVEKQCRCGKHTKRMPCHKTYLCETKCVKMRDCQKHQCRRKCCPGNCPPCDQNCGRTLGCRNHKCPSVCHRGSCYPCPETVDVKCNCGNAKVTVPCGRERTTRPPKCKELCSRPPTCHHSSQEKHRCHFGPCPPCHQPCQKVLEKCGHLCPISCHDQALVKQTGRHQLSGPWEQPAEPAFIQTALPCPPCQVPIPVECLGKHEVSPLPCHAVGPYSCKRLCGRMLNCQNHTCTKECHKVTEVDGCPGRHKAGPECLQCEEGCSKSRPAGCPHPCVLPCHPGKCPPCVQMLRIKCHCKITNLYVECRKITTADVSEKNLLSCCKNQCPKELPCGHRCKEMCHPGECPYNCNQKVKLRCPCKRIKRELPCNKIRGNQVSVECDAACKEMKRKASEIKEAEANAALEEEKRRQQAELEAFENRLKGRRKKNRKRDEVAVQLSPWQKYKSYLFPVCGVVVAVLVWYICHHAD", "length": 924, "header": "tr|A0A0G2KAF4-1|A0A0G2KAF4_RAT Isoform 1 of Nuclear transcription factor, X-box binding-like 1 OS=Rattus norvegicus OX=10116 GN=Nfxl1 PE=1 SV=1 CANONICAL=A0A0G2KAF4-1" }, "locus": { "chromosome": "14", "start_pos": 35666585, "end_pos": 35626494, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000090242.2", "url": "https://www.ensembl.org/id/ENSRNOT00000090242.2" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000075378.2", "url": "https://www.ensembl.org/id/ENSRNOP00000075378.2" } ] } }, { "isoform_ac": "F1LNF3-1", "url": "", "sequence": { "sequence": "MDASWRQVAAGRGRARGRGTAVPLSGNGVPLSGAGGGRAKGSGGAVPSAPGPRRAATPGPAGHKQRSAGGEAPQPLWVGGEDGSELISQRKFEEIKKANQAAARKLVEEHCSSSSEEEEGDEDFEGKQGKIVANTFITYTTHTDGDVHELEKTKQYLNEAFQAGAMTCLICIASVKRNQAVWSCSGCFCIFHMPCIQKWAKDSQFLVSSVTDDDFGKKDYPWPCPKCRFEYKRSETPSRYYCYCGKVEDPPLDPWLVPHSCGQVCEREFKPSCGHKCLLLCHPGECSCFWVAGHGGKKIAKQWSCQLPCGKTLPCGNHTCEQVCHVGACGECPRSGKRSCPCQKSKFSLPCTEDVPTCGDSCDKILECGIHRCSQRCHRGPCETCRQEVEKQCRCGKHTKRMPCHKTYLCETKCVKMRDCQKHQCRRKCCPGNCPPCDQNCGRTLGCRNHKCPSVCHRGSCYPCPETVDVKCNCGNAKVTVPCGRERTTRPPKCKELCSRPPTCHHSSQEKHRCHFGPCPPCHQPCQKVLEKCGHLCPISCHDQALVKQTGRHQLSGPWEQPAEPAFIQTALPCPPCQVPIPVECLGKHEVSPLPCHAVGPYSCKRLCGRMLNCQNHTCTKECHKVTEVDGCPGRHKAGPECLQCEEGCSKSRPAGCPHPCVLPCHPGKCPPCVQMLRIKCHCKITNLYVECRKITTADVSEKNLLSCCKNQCPKELPCGHRCKEMCHPGECPYNCNQKVKLRCPCKRIKRVSILNDRIPVCVDSYLALILRIKEAEANAALEEEKRRQQAELEAFENRLKGRRKKNRKRDEVAVQLSPWQKYKSYLFPVCGVVVAVLVWYICHHAD", "length": 847, "header": "tr|F1LNF3-1|F1LNF3_RAT Computationally mapped isoform of Nuclear transcription factor, X-box binding-like 1 OS=Rattus norvegicus OX=10116 GN=Nfxl1 PE=3 SV=2 CANONICAL=A0A0G2KAF4-1" }, "locus": { "chromosome": "14", "start_pos": 35666585, "end_pos": 35626494, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000077080.2", "url": "https://www.ensembl.org/id/ENSRNOT00000077080.2" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000074217.2", "url": "https://www.ensembl.org/id/ENSRNOP00000074217.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "rno:289595", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:289595", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KAF4", "url": "https://www.uniprot.org/uniprot/A0A0G2KAF4" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KAF4", "url": "https://www.uniprot.org/uniprot/A0A0G2KAF4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KAF4", "url": "https://www.uniprot.org/uniprot/A0A0G2KAF4" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KAF4", "url": "https://www.uniprot.org/uniprot/A0A0G2KAF4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KAF4", "url": "https://www.uniprot.org/uniprot/A0A0G2KAF4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2KAF4", "url": "https://www.uniprot.org/uniprot/A0A0G2KAF4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 386, "end_pos": 388, "annotation": "n_glycosylation_sequon" }, { "start_pos": 685, "end_pos": 687, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "synthesized_glycans": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }