{
    "uniprot_canonical_ac": "A0A0G2KA54-1",
    "uniprot_ac": "A0A0G2KA54",
    "uniprot_id": "A0A0G2KA54_RAT",
    "mass": {
        "chemical_mass": 73112.0,
        "monoisotopic_mass": 73112.0
    },
    "refseq": {},
    "gene_names": [
        {
            "name": "Kng1",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A0G2KA54",
            "id": "A0A0G2KA54"
        },
        {
            "name": "Kng1l1",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0G2KA54",
            "id": "A0A0G2KA54"
        },
        {
            "name": "Kng2",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0G2KA54",
            "id": "A0A0G2KA54"
        }
    ],
    "protein_names": [
        {
            "name": "Kininogen 1",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "A0A0G2KA54"
        }
    ],
    "function": [],
    "disease": [
        {
            "disease_id": "DOID:0111676",
            "recommended_name": {
                "id": "DOID:0111676",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0111676",
                "name": "high molecular weight kininogen deficiency",
                "description": "A blood coagulation disease characterized by deficiency of high molecular weight kininogen but not of low molecular weight kininogen resulting in abnormal surface-mediated activation of fibrinolysis that has_material_basis_in homozygous or compound heterozygous mutation in the KNG1 gene on chromosome 3q27.3. Both high and low molecular weight kininogen are encoded by the KNG1 gene."
            },
            "synonyms": [
                {
                    "id": "DOID:0111676",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0111676",
                    "name": "Fitzgerald trait",
                    "description": ""
                },
                {
                    "id": "DOID:0111676",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0111676",
                    "name": "HMWK deficiency",
                    "description": ""
                },
                {
                    "id": "DOID:0111676",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0111676",
                    "name": "congenital high-molecular-weight kininogen deficiency",
                    "description": ""
                },
                {
                    "id": "MONDO:0009234",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009234",
                    "name": "congenital high-molecular-weight kininogen deficiency",
                    "description": "A rare autosomal recessive inherited disorder characterized by prolonged partial thromboplastin time and absence of bleeding diathesis."
                },
                {
                    "id": "MONDO:0009234",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009234",
                    "name": "high molecular weight kininogen deficiency",
                    "description": ""
                },
                {
                    "id": "MONDO:0009234",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009234",
                    "name": "kininogen deficiency",
                    "description": ""
                },
                {
                    "id": "MONDO:0009234",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009234",
                    "name": "Fitzgerald trait",
                    "description": ""
                },
                {
                    "id": "MONDO:0009234",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009234",
                    "name": "Fitzgerald trait kininogen deficiency, total, included",
                    "description": ""
                },
                {
                    "id": "MONDO:0009234",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009234",
                    "name": "Flaujeac factor deficiency",
                    "description": ""
                },
                {
                    "id": "MONDO:0009234",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009234",
                    "name": "Flaujeac trait",
                    "description": ""
                },
                {
                    "id": "MONDO:0009234",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009234",
                    "name": "Flaujeac trait, included",
                    "description": ""
                },
                {
                    "id": "MONDO:0009234",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009234",
                    "name": "HMWK",
                    "description": ""
                },
                {
                    "id": "MONDO:0009234",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009234",
                    "name": "HMWK deficiency",
                    "description": ""
                },
                {
                    "id": "MONDO:0009234",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009234",
                    "name": "Williams trait",
                    "description": ""
                },
                {
                    "id": "MONDO:0009234",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009234",
                    "name": "Williams trait, included",
                    "description": ""
                },
                {
                    "id": "MONDO:0009234",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009234",
                    "name": "high-molecular-weight kininogen deficiency, congenital",
                    "description": ""
                },
                {
                    "id": "MONDO:0009234",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009234",
                    "name": "kininogen deficiency, high molecular weight",
                    "description": ""
                },
                {
                    "id": "MONDO:0009234",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009234",
                    "name": "kininogen deficiency, high molecular weight and LOW molecular weight, included",
                    "description": ""
                },
                {
                    "id": "MONDO:0009234",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009234",
                    "name": "kininogen deficiency, high molecular weight and Low molecular weight",
                    "description": ""
                },
                {
                    "id": "MONDO:0009234",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009234",
                    "name": "kininogen deficiency, total",
                    "description": ""
                },
                {
                    "id": "MIM:228960",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/228960",
                    "name": "High molecular weight kininogen deficiency",
                    "description": "High molecular weight kininogen deficiency"
                }
            ],
            "evidence": [
                {
                    "id": "0111676",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0111676"
                }
            ]
        },
        {
            "disease_id": "DOID:11123",
            "recommended_name": {
                "id": "DOID:11123",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:11123",
                "name": "Henoch-Schoenlein purpura",
                "description": "A hypersensitivity vasculitis that is characterized by purpura (purplish plaques), arthralgia, gastrointestinal upset, and/or glomerulonephritis, and may be related to increased immune response following an infection."
            },
            "synonyms": [
                {
                    "id": "DOID:11123",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:11123",
                    "name": "Allergic purpura",
                    "description": ""
                },
                {
                    "id": "DOID:11123",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:11123",
                    "name": "Autoimmune purpura",
                    "description": ""
                },
                {
                    "id": "DOID:11123",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:11123",
                    "name": "Henoch-Sch?nlein purpura",
                    "description": ""
                },
                {
                    "id": "DOID:11123",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:11123",
                    "name": "Henoch-Sch@nlein purpura",
                    "description": ""
                },
                {
                    "id": "DOID:11123",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:11123",
                    "name": "Henoch-Scholein purpura",
                    "description": ""
                },
                {
                    "id": "DOID:11123",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:11123",
                    "name": "Henoch-Schonlein Purpura",
                    "description": ""
                },
                {
                    "id": "DOID:11123",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:11123",
                    "name": "Purpura, autoimmune",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "11123",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:11123"
                }
            ]
        },
        {
            "disease_id": "DOID:14735",
            "recommended_name": {
                "id": "DOID:14735",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:14735",
                "name": "hereditary angioedema",
                "description": "An angioedema that is characterized by recurrent episodes of severe swelling of the skin and mucous membranes."
            },
            "synonyms": [
                {
                    "id": "DOID:14735",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:14735",
                    "name": "HANE",
                    "description": ""
                },
                {
                    "id": "DOID:14735",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:14735",
                    "name": "Hereditary angioneurotic edema",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "14735",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:14735"
                }
            ]
        },
        {
            "disease_id": "DOID:7693",
            "recommended_name": {
                "id": "DOID:7693",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:7693",
                "name": "abdominal aortic aneurysm",
                "description": "An aortic aneurysm that is located_in the abdominal aorta."
            },
            "synonyms": [
                {
                    "id": "DOID:7693",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:7693",
                    "name": "AORTIC ANEURYSM, FAMILIAL ABDOMINAL 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0012343",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012343",
                    "name": "aortic aneurysm, familial abdominal, 2",
                    "description": ""
                },
                {
                    "id": "MONDO:0012343",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012343",
                    "name": "AAA2",
                    "description": ""
                },
                {
                    "id": "MONDO:0012343",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012343",
                    "name": "aortic aneurysm, familial abdominal 2",
                    "description": ""
                },
                {
                    "id": "MONDO:0012343",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012343",
                    "name": "aortic aneurysm, familial abdominal, 2",
                    "description": ""
                },
                {
                    "id": "MONDO:0024521",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0024521",
                    "name": "aortic aneurysm, familial abdominal, 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0024521",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0024521",
                    "name": "AAA1",
                    "description": ""
                },
                {
                    "id": "MONDO:0024521",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0024521",
                    "name": "aortic aneurysm, familial abdominal 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0024521",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0024521",
                    "name": "aortic aneurysm, familial abdominal, 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0024521",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0024521",
                    "name": "abdominal aortic aneurysm",
                    "description": ""
                },
                {
                    "id": "MONDO:0024521",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0024521",
                    "name": "aneurysm, abdominal aortic",
                    "description": ""
                },
                {
                    "id": "MONDO:0013716",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013716",
                    "name": "aortic aneurysm, familial abdominal, 4",
                    "description": ""
                },
                {
                    "id": "MONDO:0013716",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013716",
                    "name": "AAA4",
                    "description": ""
                },
                {
                    "id": "MONDO:0013716",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013716",
                    "name": "aortic aneurysm, familial abdominal, 4",
                    "description": ""
                },
                {
                    "id": "MONDO:0012751",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012751",
                    "name": "aortic aneurysm, familial abdominal, 3",
                    "description": ""
                },
                {
                    "id": "MONDO:0012751",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012751",
                    "name": "AAA3",
                    "description": ""
                },
                {
                    "id": "MONDO:0012751",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012751",
                    "name": "aneurysm, familial abdominal 3",
                    "description": ""
                },
                {
                    "id": "MONDO:0012751",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012751",
                    "name": "aortic aneurysm, familial abdominal, 3",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "7693",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:7693"
                }
            ]
        },
        {
            "disease_id": "DOID:9719",
            "recommended_name": {
                "id": "DOID:9719",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:9719",
                "name": "neovascular inflammatory vitreoretinopathy",
                "description": "A retinal and vitreous disease characterized by ocular inflammation, vascular dropout, large spots of hyperpigmentation, neovascularization of the peripheral and posterior retina, vitreous hemorrhage, and retinal detachment that has_material_basis_in heterozygous mutation in the CAPN5 gene on chromosome 11q13.5."
            },
            "synonyms": [
                {
                    "id": "DOID:9719",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:9719",
                    "name": "ADNIV",
                    "description": ""
                },
                {
                    "id": "DOID:9719",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:9719",
                    "name": "Retinitis proliferans",
                    "description": ""
                },
                {
                    "id": "DOID:9719",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:9719",
                    "name": "proliferative vitreoretinopathy",
                    "description": ""
                },
                {
                    "id": "DOID:9719",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:9719",
                    "name": "autosomal dominant neovascular inflammatory vitreoretinopathy",
                    "description": ""
                },
                {
                    "id": "MONDO:0100450",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0100450",
                    "name": "CAPN5-related vitreoretinopathy",
                    "description": "An autosomal dominant vitreoretinopathy caused by variants in the CAPN5 gene. Additional features, such as developmental delay and hypotonia, have been reported in some patients."
                },
                {
                    "id": "MONDO:0100450",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0100450",
                    "name": "proliferative vitreoretinopathy",
                    "description": ""
                },
                {
                    "id": "MONDO:0100450",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0100450",
                    "name": "ADNIV",
                    "description": ""
                },
                {
                    "id": "MONDO:0100450",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0100450",
                    "name": "CAPN5 vitreoretinopathy",
                    "description": ""
                },
                {
                    "id": "MONDO:0100450",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0100450",
                    "name": "VRNI",
                    "description": ""
                },
                {
                    "id": "MONDO:0100450",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0100450",
                    "name": "autosomal dominant neovascular inflammatory vitreoretinopathy",
                    "description": ""
                },
                {
                    "id": "MONDO:0100450",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0100450",
                    "name": "retinitis proliferans",
                    "description": ""
                },
                {
                    "id": "MONDO:0100450",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0100450",
                    "name": "vitreoretinopathy, neovascular inflammatory",
                    "description": ""
                },
                {
                    "id": "MONDO:0100450",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0100450",
                    "name": "vitreoretinopathy, neovascular inflammatory, autosomal dominant",
                    "description": ""
                },
                {
                    "id": "MIM:193235",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/193235",
                    "name": "Vitreoretinopathy, neovascular inflammatory",
                    "description": "Vitreoretinopathy, neovascular inflammatory"
                }
            ],
            "evidence": [
                {
                    "id": "9719",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:9719"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A0G2KA54",
                    "url": "https://www.uniprot.org/uniprot/A0A0G2KA54"
                }
            ],
            "common_name": "Rat"
        }
    ],
    "gene": [
        {
            "name": "Kng1",
            "url": "https://www.uniprot.org/uniprot/A0A0G2KA54",
            "locus": {
                "chromosome": "11",
                "start_pos": 77812752,
                "end_pos": 77835555,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSRNOG00000030387",
                        "url": "https://www.ensembl.org/id/ENSRNOG00000030387"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSRNOG00000030387",
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000030387",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "cd00042",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00042",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR000010",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000010",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR002395",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR002395",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR018073",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR018073",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR027358",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR027358",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR046350",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR046350",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR13814",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13814",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR13814:SF12",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13814:SF12",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR13814:SF16",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13814:SF16",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00031",
            "url": "http://pfam.xfam.org/family/PF00031",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "1359376",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1359376",
            "database": "RGD",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "A0A0G2KA54",
            "url": "https://www.uniprot.org/uniprot/A0A0G2KA54",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A0G2KA54-1",
            "url": "https://www.uniprot.org/uniprot/A0A0G2KA54-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8L2R8P7",
            "url": "https://www.uniprot.org/uniprot/A0A8L2R8P7",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8L2R8P7-1",
            "url": "https://www.uniprot.org/uniprot/A0A8L2R8P7-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "F7EUK4",
            "url": "https://www.uniprot.org/uniprot/F7EUK4",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "F7EUK4-1",
            "url": "https://www.uniprot.org/uniprot/F7EUK4-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MKLITILLLCSRLLPSLAQEEGAQEMDCNDETVFQAVDTALKKYNAELESGNQFLLYRVTEGTKKDGAETLYSFKYQIKEGNCSVQSGLTWQDCDFKDAEEAATGECTTTLGKKENKFSVATQICNITPGKGPKKTEEDLCVGCFQPIPMDSSDLKPVLKHAVEHFNNNTKHTHLFALTEVKSAHSQVVAGMNYKIIYSIVQTNCSKEDFPFLREDCVPLPYGDHGECRGHTYVDIHNTIAGFSQSCDLYPGDDLFSLLPKKCFGCPKNIPVDSPELKEALGHSIAQLNAQHNHLFYFKIDTVKKATSQVVAGTKYVIEFIARETNCSKQTNTELTADCETKHLGQSLNCNANVYMRPWENKVVPTVRCQALDMMISRPPGFSPFRLVQVQETKEGTTVSPPYIARVQEERDPGNQGPIHGHGWFHAKQIKDKNHQGHKHGHDHGCWPPKRHGLSNGHQKPHGLGHGHKHKLDDLKQQRDDGYNYRHPMGHGHGYGLGHGYGHGHVHSHGLGHGYGQGQGHGEGKHTNKDKNNVKHTDQRAEPLTSSSEDSTTSTQIQGRTEGFTLNPPLAQPDVISRGFQDSGFTEGVIATTSPYDTENHDDLIPDIHVQPDSLSFKLISDFPTSHNCPGHPWKPVGRKDPTTETAEFSDFDLLGALS",
        "length": 659,
        "header": "tr|A0A0G2KA54-1|A0A0G2KA54_RAT Isoform 1 of Kininogen 1  OS=Rattus norvegicus OX=10116 GN=Kng1 PE=4 SV=2 CANONICAL=A0A0G2KA54-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A0G2KA54-1",
            "url": "",
            "sequence": {
                "sequence": "MKLITILLLCSRLLPSLAQEEGAQEMDCNDETVFQAVDTALKKYNAELESGNQFLLYRVTEGTKKDGAETLYSFKYQIKEGNCSVQSGLTWQDCDFKDAEEAATGECTTTLGKKENKFSVATQICNITPGKGPKKTEEDLCVGCFQPIPMDSSDLKPVLKHAVEHFNNNTKHTHLFALTEVKSAHSQVVAGMNYKIIYSIVQTNCSKEDFPFLREDCVPLPYGDHGECRGHTYVDIHNTIAGFSQSCDLYPGDDLFSLLPKKCFGCPKNIPVDSPELKEALGHSIAQLNAQHNHLFYFKIDTVKKATSQVVAGTKYVIEFIARETNCSKQTNTELTADCETKHLGQSLNCNANVYMRPWENKVVPTVRCQALDMMISRPPGFSPFRLVQVQETKEGTTVSPPYIARVQEERDPGNQGPIHGHGWFHAKQIKDKNHQGHKHGHDHGCWPPKRHGLSNGHQKPHGLGHGHKHKLDDLKQQRDDGYNYRHPMGHGHGYGLGHGYGHGHVHSHGLGHGYGQGQGHGEGKHTNKDKNNVKHTDQRAEPLTSSSEDSTTSTQIQGRTEGFTLNPPLAQPDVISRGFQDSGFTEGVIATTSPYDTENHDDLIPDIHVQPDSLSFKLISDFPTSHNCPGHPWKPVGRKDPTTETAEFSDFDLLGALS",
                "length": 659,
                "header": "tr|A0A0G2KA54-1|A0A0G2KA54_RAT Isoform 1 of Kininogen 1  OS=Rattus norvegicus OX=10116 GN=Kng1 PE=4 SV=2 CANONICAL=A0A0G2KA54-1"
            },
            "locus": {
                "chromosome": "11",
                "start_pos": 77835464,
                "end_pos": 77814402,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000078131.2",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000078131.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000075264.2",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000075264.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A8L2R8P7-1",
            "url": "",
            "sequence": {
                "sequence": "MKLITILLLCSRLLPSLAQEEGAQEMDCNDETVFQAVDTALKKYNAELESGNQFLLYRVTEGTKKDGAETLYSFKYQIKEGNCSVQSGLTWQDCDFKDAEEAATGECTTTLGKKENKFSVATQICNITPGKGPKKTEEDLCVGCFQPIPMDSSDLKPVLKHAVEHFNNNTKHTHLFALTEVKSAHSQVVAGMNYKIIYSIVQTNCSKEDFPFLREDCVPLPYGDHGECRGHTYVDIHNTIAGFSQSCDLYPGDDLFSLLPKKCFGCPKNIPVDSPELKEALGHSIAQLNAQHNHLFYFKIDTVKKATSQVVAGTKYVIEFIARETNCSKQTNTELTADCETKHLGQSLNCNANVYMRPWENKVVPTVRCQALDMMISRPPGFSPFRLVQVQETKEGTTHFTILQRLLNSCEYKGRLSKAGAGPAPDHQAEASTVTP",
                "length": 436,
                "header": "tr|A0A8L2R8P7-1|A0A0G2KA54_RAT Computationally mapped isoform of Kininogen 1  OS=Rattus norvegicus OX=10116 GN=Kng1 PE=4 SV=1 CANONICAL=A0A0G2KA54-1"
            },
            "locus": {
                "chromosome": "11",
                "start_pos": 77835464,
                "end_pos": 77812871,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000084867.2",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000084867.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000073812.2",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000073812.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "F7EUK4-1",
            "url": "",
            "sequence": {
                "sequence": "MKLITILLLCSRLLPSLAQEEGAQEMDCNDETVFQAVDTALKKYNAELESGNQFLLYRVTEGTKKDGAETLYSFKYQIKEGNCSVQSGLTWQDCDFKDAEEAATGECTTTLGKKENKFSVATQICNITPGKGPKKTEEDLCVGCFQPIPMDSSDLKPVLKHAVEHFNNNTKHTHLFALTEVKSAHSQVVAGMNYKIIYSIVQTNCSKEDFPFLREDCVPLPYGDHGECRGHTYVDIHNTIAGFSQSCDLYPGDDLFSLLPKKCFGCPKNIPVDSPELKEALGHSIAQLNAQHNHLFYFKIDTVKKATSQVVAGTKYVIEFIARETNCSKQTNTELTADCETKHLGQSLNCNANVYMRPWENKVVPTVRCQALMLTRCIPLNISHFTILQRLLNSCEYKGRLSKAGAGPAPDHQAEASTVTP",
                "length": 421,
                "header": "tr|F7EUK4-1|F7EUK4_RAT Computationally mapped isoform of Kininogen 1  OS=Rattus norvegicus OX=10116 GN=Kng1 PE=4 SV=3 CANONICAL=A0A0G2KA54-1"
            },
            "locus": {
                "chromosome": "11",
                "start_pos": 77835464,
                "end_pos": 77812871,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000058479.5",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000058479.5"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000055278.5",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000055278.5"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [],
    "orthologs": [],
    "go_annotation": {
        "categories": [
            {
                "name": "Cellular Component",
                "total": 1,
                "go_terms": [
                    {
                        "name": "extracellular space",
                        "id": "GO:0005615",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KA54",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KA54"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 3,
                "go_terms": [
                    {
                        "name": "vasodilation",
                        "id": "GO:0042311",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042311",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KA54",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KA54"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "inflammatory response",
                        "id": "GO:0006954",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KA54",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KA54"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "blood coagulation",
                        "id": "GO:0007596",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007596",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KA54",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KA54"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 1,
                "go_terms": [
                    {
                        "name": "cysteine-type endopeptidase inhibitor activity",
                        "id": "GO:0004869",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004869",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KA54",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KA54"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 126,
            "end_pos": 128,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 168,
            "end_pos": 170,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 204,
            "end_pos": 206,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 326,
            "end_pos": 328,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 82,
            "end_pos": 84,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        }
    ],
    "section_stats": [
        {
            "table_id": "glycosylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
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                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported",
            "table_stats": [
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                    "field": "total",
                    "count": 0
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                {
                    "field": "total_sites",
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                },
                {
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                {
                    "field": "n_linked_glycan_sites",
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                {
                    "field": "o_linked_glycans",
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                {
                    "field": "o_linked_glycan_sites",
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                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported_with_glycan",
            "table_stats": [
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                    "field": "total",
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                {
                    "field": "total_sites",
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        {
            "table_id": "glycosylation_predicted",
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                    "field": "total_sites",
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                {
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                {
                    "field": "o_linked_glycan_sites",
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            "sort_fields": []
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        {
            "table_id": "glycosylation_automatic_literature_mining",
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                    "field": "total",
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                    "field": "total_sites",
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                    "field": "n_linked_glycan_sites",
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                {
                    "field": "o_linked_glycan_sites",
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            ],
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        {
            "table_id": "phosphorylation",
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                    "field": "total",
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                {
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            ],
            "sort_fields": []
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        {
            "table_id": "snv",
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        {
            "table_id": "snv_disease",
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        {
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    ]
}