{
    "uniprot_canonical_ac": "A0A0G2K8I5-1",
    "uniprot_ac": "A0A0G2K8I5",
    "uniprot_id": "A0A0G2K8I5_RAT",
    "mass": {
        "chemical_mass": 125989.0,
        "monoisotopic_mass": 125989.0
    },
    "refseq": {
        "ac": "NP_001162600",
        "name": "protocadherin-19 precursor",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001162600"
    },
    "gene_names": [
        {
            "name": "Pcdh19",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K8I5",
            "id": "A0A0G2K8I5"
        },
        {
            "name": "Pcdh19",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006257284",
            "id": "XP_006257284"
        },
        {
            "name": "RGD1565392",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006257284",
            "id": "XP_006257284"
        }
    ],
    "protein_names": [
        {
            "name": "Protocadherin 19",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "A0A0G2K8I5"
        },
        {
            "name": "protocadherin-19 isoform X3",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006257284",
            "id": "XP_006257284"
        },
        {
            "name": "protocadherin-19 precursor",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001162600",
            "id": "NP_001162600"
        }
    ],
    "function": [
        {
            "annotation": "The Epilepsy-Related Protein PCDH19 Regulates Tonic Inhibition, GABAAR Kinetics, and the Intrinsic Excitability of Hippocampal Neurons.",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001162600",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001162600"
                },
                {
                    "database": "PubMed",
                    "id": "32880860",
                    "url": "https://glygen.org/publication/PubMed/32880860"
                }
            ]
        }
    ],
    "disease": [
        {
            "disease_id": "DOID:0060848",
            "recommended_name": {
                "id": "DOID:0060848",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0060848",
                "name": "developmental and epileptic encephalopathy 9",
                "description": "A developmental and epileptic encephalopathy characterized by seizure onset in infancy and mild to severe intellectual impairment in females that has_material_basis_in heterozygous mutation in the gene encoding protocadherin-19 (PCDH19) on chromosome Xq22."
            },
            "synonyms": [
                {
                    "id": "DOID:0060848",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0060848",
                    "name": "early infantile epileptic encephalopathy 9",
                    "description": ""
                },
                {
                    "id": "DOID:0060848",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0060848",
                    "name": "early infantile female-limited epilecptic encephalopathy",
                    "description": ""
                },
                {
                    "id": "DOID:0060848",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0060848",
                    "name": "EFMR",
                    "description": ""
                },
                {
                    "id": "DOID:0060848",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0060848",
                    "name": "EIEE9",
                    "description": ""
                },
                {
                    "id": "DOID:0060848",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0060848",
                    "name": "Juberg Hellman syndrome",
                    "description": ""
                },
                {
                    "id": "DOID:0060848",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0060848",
                    "name": "female restricted epilepsy with mental retardation",
                    "description": ""
                },
                {
                    "id": "DOID:0060848",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0060848",
                    "name": "DEE9",
                    "description": ""
                },
                {
                    "id": "MONDO:0010246",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010246",
                    "name": "developmental and epileptic encephalopathy, 9",
                    "description": "Female restricted epilepsy with intellectual disability is a rare X-linked epilepsy syndrome characterized by febrile or afebrile seizures (mainly tonic-clonic, but also absence, myoclonic, and atonic) starting in the first years of life and, in most cases, developmental delay and intellectual disability of variable severity. Behavioral disturbances (e.g. autistic features, hyperactivity, and aggressiveness) are also frequently associated. This disease affects exclusively females, with male carriers being unaffected, despite an X-linked inheritance."
                },
                {
                    "id": "MONDO:0010246",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010246",
                    "name": "DEE9",
                    "description": ""
                },
                {
                    "id": "MONDO:0010246",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010246",
                    "name": "EFMR",
                    "description": ""
                },
                {
                    "id": "MONDO:0010246",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010246",
                    "name": "EIEE9",
                    "description": ""
                },
                {
                    "id": "MONDO:0010246",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010246",
                    "name": "Juberg Hellman syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0010246",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010246",
                    "name": "Juberg-Hellman syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0010246",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010246",
                    "name": "PCDH19 early infantile epileptic encephalopathy",
                    "description": ""
                },
                {
                    "id": "MONDO:0010246",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010246",
                    "name": "developmental and epileptic encephalopathy 9",
                    "description": ""
                },
                {
                    "id": "MONDO:0010246",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010246",
                    "name": "developmental and epileptic encephalopathy, 9",
                    "description": ""
                },
                {
                    "id": "MONDO:0010246",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010246",
                    "name": "early infantile epileptic encephalopathy 9",
                    "description": ""
                },
                {
                    "id": "MONDO:0010246",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010246",
                    "name": "early infantile epileptic encephalopathy caused by mutation in PCDH19",
                    "description": ""
                },
                {
                    "id": "MONDO:0010246",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010246",
                    "name": "early infantile epileptic encephalopathy type 9",
                    "description": ""
                },
                {
                    "id": "MONDO:0010246",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010246",
                    "name": "early infantile female-limited epilecptic encephalopathy",
                    "description": ""
                },
                {
                    "id": "MONDO:0010246",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010246",
                    "name": "epileptic encephalopathy, early infantile, 9",
                    "description": ""
                },
                {
                    "id": "MONDO:0010246",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010246",
                    "name": "epileptic encephalopathy, early infantile, type 9",
                    "description": ""
                },
                {
                    "id": "MONDO:0010246",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010246",
                    "name": "familial epilepsy and intellectual disability limited to females",
                    "description": ""
                },
                {
                    "id": "MONDO:0010246",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010246",
                    "name": "familial epilepsy and mental retardation limited to females",
                    "description": ""
                },
                {
                    "id": "MONDO:0010246",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010246",
                    "name": "female restricted epilepsy with intellectual disability",
                    "description": ""
                },
                {
                    "id": "MONDO:0010246",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010246",
                    "name": "female restricted epilepsy with mental retardation",
                    "description": ""
                },
                {
                    "id": "MONDO:0010246",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010246",
                    "name": "PCDH19-related FLE",
                    "description": ""
                },
                {
                    "id": "MONDO:0010246",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010246",
                    "name": "PCDH19-related female-limited epilepsy",
                    "description": ""
                },
                {
                    "id": "MONDO:0010246",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010246",
                    "name": "PCDH19-related infantile epileptic encephalopathy",
                    "description": ""
                },
                {
                    "id": "MONDO:0010246",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010246",
                    "name": "epilepsy and intellectual disability limited to females",
                    "description": ""
                },
                {
                    "id": "MONDO:0010246",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010246",
                    "name": "epilepsy and mental retardation limited to females",
                    "description": ""
                },
                {
                    "id": "MONDO:0010246",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010246",
                    "name": "epilepsy, female restricted, with intellectual disability",
                    "description": ""
                },
                {
                    "id": "MONDO:0010246",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010246",
                    "name": "epilepsy, female restricted, with mental retardation",
                    "description": ""
                },
                {
                    "id": "MONDO:0010246",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010246",
                    "name": "epilepsy, female-restricted, with intellectual disability",
                    "description": ""
                },
                {
                    "id": "MONDO:0010246",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010246",
                    "name": "epilepsy, female-restricted, with mental retardation",
                    "description": ""
                },
                {
                    "id": "MONDO:0010246",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010246",
                    "name": "female restricted epilepsy with intellectual deficit",
                    "description": ""
                },
                {
                    "id": "MIM:300088",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/300088",
                    "name": "Developmental and epileptic encephalopathy 9",
                    "description": "Developmental and epileptic encephalopathy 9"
                }
            ],
            "evidence": [
                {
                    "id": "0060848",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060848"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A0G2K8I5",
                    "url": "https://www.uniprot.org/uniprot/A0A0G2K8I5"
                }
            ],
            "common_name": "Rat"
        }
    ],
    "gene": [
        {
            "name": "Pcdh19",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K8I5",
            "locus": {
                "chromosome": "X",
                "start_pos": 96771947,
                "end_pos": 96873524,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSRNOG00000003929",
                        "url": "https://www.ensembl.org/id/ENSRNOG00000003929"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSRNOG00000003929",
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000003929",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "cd11304",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11304",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "317183",
            "url": "https://www.ncbi.nlm.nih.gov/gene/317183",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR002126",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR002126",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR013164",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013164",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR015919",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR015919",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR020894",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR020894",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "rno:317183",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:317183",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "RCWMPRG",
            "url": "https://omabrowser.org/oma/group/RCWMPRG/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "4259465at2759",
            "url": "http://www.orthodb.org/?query=4259465at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR24028",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR24028:SF40",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028:SF40",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00028",
            "url": "http://pfam.xfam.org/family/PF00028",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF08266",
            "url": "http://pfam.xfam.org/family/PF08266",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "XP_006257284",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006257284",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "1565392",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1565392",
            "database": "RGD",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "A0A0G2K8I5",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K8I5",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A0G2K8I5-1",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K8I5-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "D3ZG18",
            "url": "https://www.uniprot.org/uniprot/D3ZG18",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "D3ZG18-1",
            "url": "https://www.uniprot.org/uniprot/D3ZG18-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MESLLLPVLLLLAVLWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFAMDTRQASAFRVVSNSAPHLVDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEVMSSSMEICVIKVEIKDLNDNAPSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKTRGDGSRFAELVVEKSLDRETQSHYSFRITALDGGDPPHMGTVGLTIKVTDSNDNNPVFGESTYSVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTVTGALDYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPIINLLSVNSELVEVSESAPPGYVIALVRVSDRDSGLNGRVQCRLLGNVPFRLQEYESFSTILVDGRLDREQHDQYNLTIQARDSGVPMLQSAKSFTVRITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDPDLGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGMPSLQSNATVRVIILDVNDNTPVITAPPLINGTAEVYIPRNSGIGYLVTVVKADDYDEGENGRVTYDMTEGDRGFFEIDQVNGEVRTTRTFNENSKASYELIVVAHDHGKTSLSASALVLIYLSPALDAQESMGSVNLSLIFIIALGSIAGILFVTMIFVAIKCKRDNKEIRTYNCSNCLTITCLLGCFIKGQNSKCLHCISVSPISEEQDKKAEEKVSLRGKRIAEYSYGHQKKSSKKKKISKNDIRLVPRDVEETDKMNVVSCSSLTSSLNYFDYHQQTLPLGCRRSESTFLNVENQNTRNTTANHIYHHSFNSQGPQQPDLIINGVPLPETENYSFDSNYVNSRAHLIKSSSTFKDLEGNSLKDSGHEESDQTDSEHDVQRSLYCDTAVNDVLNTSVTSMGSHMPDHDQNDGFHCREECRILGHSDRCWMPRNPMPTRSKSPEHMRNIIALSIEATAADVEAYDDCGPTKRTFATFGKDVSSHPAEERSILKGKRTVDVTICSPKVNSAIREAGNGCEAISPVTSPLHLKSPLPTKPSMSYTVALAPPAHDLDHHANTGASRPSEAEPRGADSEKVMHEVNPILKEGRDKESPAVKRLKDIIL",
        "length": 1145,
        "header": "tr|A0A0G2K8I5-1|A0A0G2K8I5_RAT Isoform 1 of Protocadherin 19  OS=Rattus norvegicus OX=10116 GN=Pcdh19 PE=4 SV=1 CANONICAL=A0A0G2K8I5-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A0G2K8I5-1",
            "url": "",
            "sequence": {
                "sequence": "MESLLLPVLLLLAVLWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFAMDTRQASAFRVVSNSAPHLVDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEVMSSSMEICVIKVEIKDLNDNAPSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKTRGDGSRFAELVVEKSLDRETQSHYSFRITALDGGDPPHMGTVGLTIKVTDSNDNNPVFGESTYSVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTVTGALDYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPIINLLSVNSELVEVSESAPPGYVIALVRVSDRDSGLNGRVQCRLLGNVPFRLQEYESFSTILVDGRLDREQHDQYNLTIQARDSGVPMLQSAKSFTVRITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDPDLGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGMPSLQSNATVRVIILDVNDNTPVITAPPLINGTAEVYIPRNSGIGYLVTVVKADDYDEGENGRVTYDMTEGDRGFFEIDQVNGEVRTTRTFNENSKASYELIVVAHDHGKTSLSASALVLIYLSPALDAQESMGSVNLSLIFIIALGSIAGILFVTMIFVAIKCKRDNKEIRTYNCSNCLTITCLLGCFIKGQNSKCLHCISVSPISEEQDKKAEEKVSLRGKRIAEYSYGHQKKSSKKKKISKNDIRLVPRDVEETDKMNVVSCSSLTSSLNYFDYHQQTLPLGCRRSESTFLNVENQNTRNTTANHIYHHSFNSQGPQQPDLIINGVPLPETENYSFDSNYVNSRAHLIKSSSTFKDLEGNSLKDSGHEESDQTDSEHDVQRSLYCDTAVNDVLNTSVTSMGSHMPDHDQNDGFHCREECRILGHSDRCWMPRNPMPTRSKSPEHMRNIIALSIEATAADVEAYDDCGPTKRTFATFGKDVSSHPAEERSILKGKRTVDVTICSPKVNSAIREAGNGCEAISPVTSPLHLKSPLPTKPSMSYTVALAPPAHDLDHHANTGASRPSEAEPRGADSEKVMHEVNPILKEGRDKESPAVKRLKDIIL",
                "length": 1145,
                "header": "tr|A0A0G2K8I5-1|A0A0G2K8I5_RAT Isoform 1 of Protocadherin 19  OS=Rattus norvegicus OX=10116 GN=Pcdh19 PE=4 SV=1 CANONICAL=A0A0G2K8I5-1"
            },
            "locus": {
                "chromosome": "X",
                "start_pos": 96871768,
                "end_pos": 96772809,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000080386.2",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000080386.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000074621.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000074621.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "D3ZG18-1",
            "url": "",
            "sequence": {
                "sequence": "MESLLLPVLLLLAVLWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFAMDTRQASAFRVVSNSAPHLVDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEVMSSSMEICVIKVEIKDLNDNAPSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKTRGDGSRFAELVVEKSLDRETQSHYSFRITALDGGDPPHMGTVGLTIKVTDSNDNNPVFGESTYSVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTVTGALDYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPIINLLSVNSELVEVSESAPPGYVIALVRVSDRDSGLNGRVQCRLLGNVPFRLQEYESFSTILVDGRLDREQHDQYNLTIQARDSGVPMLQSAKSFTVRITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDPDLGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGMPSLQSNATVRVIILDVNDNTPVITAPPLINGTAEVYIPRNSGIGYLVTVVKADDYDEGENGRVTYDMTEGDRGFFEIDQVNGEVRTTRTFNENSKASYELIVVAHDHGKTSLSASALVLIYLSPALDAQESMGSVNLSLIFIIALGSIAGILFVTMIFVAIKCKRDNKEIRTYNCRIAEYSYGHQKKSSKKKKISKNDIRLVPRDVEETDKMNVVSCSSLTSSLNYFDYHQQTLPLGCRRSESTFLNVENQNTRNTTANHIYHHSFNSQGPQQPDLIINGVPLPETENYSFDSNYVNSRAHLIKSSSTFKDLEGNSLKDSGHEESDQTDSEHDVQRSLYCDTAVNDVLNTSVTSMGSHMPDHDQNDGFHCREECRILGHSDRCWMPRNPMPTRSKSPEHMRNIIALSIEATAADVEAYDDCGPTKRTFATFGKDVSSHPAEERSILKGKRTVDVTICSPKVNSAIREAGNGCEAISPVTSPLHLKSPLPTKPSMSYTVALAPPAHDLDHHANTGASRPSEAEPRGADSEKVMHEVNPILKEGRDKESPAVKRLKDIIL",
                "length": 1098,
                "header": "tr|D3ZG18-1|D3ZG18_RAT Computationally mapped isoform of Protocadherin 19  OS=Rattus norvegicus OX=10116 GN=Pcdh19 PE=4 SV=2 CANONICAL=A0A0G2K8I5-1"
            },
            "locus": {
                "chromosome": "X",
                "start_pos": 96871768,
                "end_pos": 96772809,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000064458.4",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000064458.4"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000062902.2",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000062902.2"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [
        {
            "title": "The Epilepsy-Related Protein PCDH19 Regulates Tonic Inhibition, GABAAR Kinetics, and the Intrinsic Excitability of Hippocampal Neurons.",
            "journal": "Molecular neurobiology",
            "date": "2020",
            "authors": "Serratto GM, Pizzi E, Murru L, Mazzoleni S, Pelucchi S, Marcello E, Mazzanti M, Passafaro M, Bassani S",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001162600",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001162600"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "32880860",
                    "url": "https://glygen.org/publication/PubMed/32880860"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "rno:317183",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:317183",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q80TF3-1",
            "protein_name": "Protocadherin-19",
            "gene_name": "Pcdh19",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MESLLLPVLLLLAVLWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQASAFRVVSNSAPHLVDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEVMSSSMEICVIKVEIKDLNDNAPSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKTRGDGSRFAELVVEKSLDRETQSHYSFRITALDGGDPPHMGTVGLSIKVTDSNDNNPVFGESTYSVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTVTGALDYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPIINLLSVNSELVEVSESAPPGYVIALVRVSDRDSGLNGRVQCRLLGNVPFRLQEYESFSTILVDGRLDREQHDQYNLTIQARDSGVPMLQSAKSFTVRITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDPDMGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGLPSLQSNATVRVIILDVNDNTPVITAPPLINGTAEVYIPRNSGIGYLVTVVKADDYDEGENGRVTYDMTEGDRGFFEIDQVNGEVRTTRTFNENSKPSYELIVVAHDHGKTSLSASALVLIYLSPALDAQESMGSVNLSLIFIIALGSIAGILFVTMIFVAIKCKRDNKEIRTYNCSNCLTITCLLGCFIKGQNSKCLHCISVSPNSEEQDKKAEEKVSLRGKRIAEYSYGHQKKSSKKKKISKNDIRLVPRDVEETDKMNVVSCSSLTSSLNYFDYHQQTLPLGCRRSESTFLNVENQNTRNTTASHIYHHSFNSQGPQQPDLIINGVPLPETENYSFDSNYVNSRAHLIKSSSTFKDLEGNSLKDSGHEESDQTDSEHDVQRSLYCDTAVNDVLNTSVTSMGSQMPDHDQNEGFHCREECRILGHSDRCWMPRNPMPTRSKSPEHVRNIIALSIEATAADVEAYDDCGPTKRTFATFGKDVSSHRAEERPILKGKRTVDVTICSPKVNSAIREAGNGCEAISPVTSPLHLKSPLPTKPSISYTVALAPPAHDLEHHANSGASRPSEAEPRGADNEKVMHEVNPIRKDGRDKESPSVKRLKDIVL",
                "length": 1145
            },
            "evidence": [
                {
                    "id": "45230315",
                    "url": "http://www.informatics.jax.org/homology/45230315",
                    "database": "MGI"
                }
            ],
            "common_name": "Mouse"
        },
        {
            "uniprot_canonical_ac": "Q8TAB3-1",
            "protein_name": "Protocadherin-19",
            "gene_name": "PCDH19",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MESLLLPVLLLLAILWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQASAFRVVSNSAPHLVDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEVMSSSMEICVIKVEIKDLNDNAPSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKTRGDGSRFAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPVFSESTYAVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTVTGALDYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSESAPPGYVIALVRVSDRDSGLNGRVQCRLLGNVPFRLQEYESFSTILVDGRLDREQHDQYNLTIQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDPDLGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGLPSLQSNATVRVIILDVNDNTPVITAPPLINGTAEVYIPRNSGIGYLVTVVKAEDYDEGENGRVTYDMTEGDRGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTSLSASALVLIYLSPALDAQESMGSVNLSLIFIIALGSIAGILFVTMIFVAIKCKRDNKEIRTYNCSNCLTITCLLGCFIKGQNSKCLHCISVSPISEEQDKKTEEKVSLRGKRIAEYSYGHQKKSSKKKKISKNDIRLVPRDVEETDKMNVVSCSSLTSSLNYFDYHQQTLPLGCRRSESTFLNVENQNTRNTSANHIYHHSFNSQGPQQPDLIINGVPLPETENYSFDSNYVNSRAHLIKSSSTFKDLEGNSLKDSGHEESDQTDSEHDVQRSLYCDTAVNDVLNTSVTSMGSQMPDHDQNEGFHCREECRILGHSDRCWMPRNPMPIRSKSPEHVRNIIALSIEATAADVEAYDDCGPTKRTFATFGKDVSDHPAEERPTLKGKRTVDVTICSPKVNSVIREAGNGCEAISPVTSPLHLKSSLPTKPSVSYTIALAPPARDLEQYVNNVNNGPTRPSEAEPRGADSEKVMHEVSPILKEGRNKESPGVKRLKDIVL",
                "length": 1148
            },
            "evidence": [
                {
                    "id": "45230315",
                    "url": "http://www.informatics.jax.org/homology/45230315",
                    "database": "MGI"
                }
            ],
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Cellular Component",
                "total": 1,
                "go_terms": [
                    {
                        "name": "plasma membrane",
                        "id": "GO:0005886",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K8I5",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K8I5"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 2,
                "go_terms": [
                    {
                        "name": "cell adhesion",
                        "id": "GO:0007155",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K8I5",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K8I5"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "homophilic cell adhesion via plasma membrane adhesion molecules",
                        "id": "GO:0007156",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K8I5",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K8I5"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 1,
                "go_terms": [
                    {
                        "name": "calcium ion binding",
                        "id": "GO:0005509",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K8I5",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K8I5"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 261,
            "end_pos": 263,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 420,
            "end_pos": 422,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 465,
            "end_pos": 467,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 485,
            "end_pos": 487,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 546,
            "end_pos": 548,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 570,
            "end_pos": 572,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 676,
            "end_pos": 678,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 714,
            "end_pos": 716,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 842,
            "end_pos": 844,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 875,
            "end_pos": 877,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 936,
            "end_pos": 938,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        },
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        }
    ],
    "section_stats": [
        {
            "table_id": "glycosylation",
            "table_stats": [
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                    "field": "total",
                    "count": 0
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                {
                    "field": "total_sites",
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                    "field": "n_linked_glycan_sites",
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                    "field": "o_linked_glycans",
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                    "field": "o_linked_glycan_sites",
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        {
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        {
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}