{ "uniprot_canonical_ac": "A0A0G2K8F2-1", "uniprot_ac": "A0A0G2K8F2", "uniprot_id": "A0A0G2K8F2_RAT", "mass": { "chemical_mass": 83369.0, "monoisotopic_mass": 83369.0 }, "refseq": {}, "gene_names": [ { "name": "Rfx4", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A0A0G2K8F2", "id": "A0A0G2K8F2" } ], "protein_names": [ { "name": "Regulatory factor X4", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "A0A0G2K8F2" } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K8F2", "url": "https://www.uniprot.org/uniprot/A0A0G2K8F2" } ], "common_name": "Rat" } ], "gene": [ { "name": "Rfx4", "url": "https://www.uniprot.org/uniprot/A0A0G2K8F2", "locus": { "chromosome": "7", "start_pos": 18853322, "end_pos": 19014967, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSRNOG00000051536", "url": "https://www.ensembl.org/id/ENSRNOG00000051536" } ] } } ], "crossref": [ { "id": "ENSRNOG00000051536", "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000051536", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR003150", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003150", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039779", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039779", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "YAHREEH", "url": "https://omabrowser.org/oma/group/YAHREEH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR12619", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12619", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12619:SF31", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12619:SF31", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02257", "url": "http://pfam.xfam.org/family/PF02257", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "1562092", "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1562092", "database": "RGD", "categories": [ "Organism-specific" ] }, { "id": "A0A0G2K3G6", "url": "https://www.uniprot.org/uniprot/A0A0G2K3G6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0G2K3G6-1", "url": "https://www.uniprot.org/uniprot/A0A0G2K3G6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0G2K8F2", "url": "https://www.uniprot.org/uniprot/A0A0G2K8F2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0G2K8F2-1", "url": "https://www.uniprot.org/uniprot/A0A0G2K8F2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I5XZT6", "url": "https://www.uniprot.org/uniprot/A0A8I5XZT6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I5XZT6-1", "url": "https://www.uniprot.org/uniprot/A0A8I5XZT6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHCGLLEEPDMDSTESWIERCLNESENKRYSSHTSLGNVSNDENEEKENNRASKPHSTPATLQWLEENYEIAEGVCIPRSALYMHYLDFCEKNDTQPVNAASFGKIIRQQFPQLTTRRLGTRGQSKYHYYGIAVKESSQYYDVMYSKKGAAWVSETGKREVTKQTVAYSPRSKLGTLLPDFPNVKDLNLPASLPEEKVSTFIMMYRTHCQRILDTVIRANFDEVQSFLLHFWQGMPPHMLPVLGSSTVVNIVGVCDSILYKAISGVLMPTVLQALPDSLTQVIRKFAKQLDEWLKVALHDLPENLRNIKFELSRRFSQILRRQTSLNHLCQASRTVIHSADITFQMLEDWRNVDLSSITKQTLYTMEDSRDEHRRLIIQLYQEFDHLLEEQSPIESYIEWLDTMVDRCVVKVAAKRQGSLKKVAQQFLLMWSCFGTRVIRDMTLHSAPSFGSFHLIHLMFDDYVLYLLESLHCQERANELMRAMKGEGSTAEAQEEIILTEATPPTPSPGPSFSPAKSATSVEVPPPSSPVSNPSPEYTGLSTTGAMQSYTWSLTYTVTTAAGSPAENSQQLPCMRSTHVPSSSVTHRIPVYSHREEHGYTGSYNYGSYGNQHPHPLQNQYPALPHDTAISGPLHYSPYHRSSAQYPFNSPTSRMEPCLMSSTPRLHPTPVTPRWPEVPTANACYTSPSVHSTRYGNSSDMYTPLTTRRNSEYEHMQHFPGFAYINGEASTGWAK", "length": 735, "header": "tr|A0A0G2K8F2-1|A0A0G2K8F2_RAT Isoform 1 of Regulatory factor X4 OS=Rattus norvegicus OX=10116 GN=Rfx4 PE=4 SV=2 CANONICAL=A0A0G2K8F2-1" }, "isoforms": [ { "isoform_ac": "A0A0G2K3G6-1", "url": "", "sequence": { "sequence": "MNWAAFGGPEFFIPGDMQMETSCPLGRDLTEWYHYYGIAVKESSQYYDVMYSKKGAAWVSETGKREVTKQTVAYSPRSKLGTLLPDFPNVKDLNLPASLPEEKVSTFIMMYRTHCQRILDTVIRANFDEVQSFLLHFWQGMPPHMLPVLGSSTVVNIVGVCDSILYKAISGVLMPTVLQALPDSLTQVIRKFAKQLDEWLKVALHDLPENLRNIKFELSRRFSQILRRQTSLNHLCQASRTVIHSADITFQMLEDWRNVDLSSITKQTLYTMEDSRDEHRRLIIQLYQEFDHLLEEQSPIESYIEWLDTMVDRCVVKVAAKRQGSLKKVAQQFLLMWSCFGTRVIRDMTLHSAPSFGSFHLIHLMFDDYVLYLLESLHCQERANELMRAMKGEGSTAEAQEEIILTEATPPTPSPGPSFSPAKSATSVEVPPPSSPVSNPSPEYTGLSTTGAMQSYTWSLTYTVTTAAGSPAENSQQLPCMRSTHVPSSSVTHRIPVYSHREEHGYTGSYNYGSYGNQHPHPLQNQYPALPHDTAISGPLHYSPYHRSSAQYPFNSPTSRMEPCLMSSTPRLHPTPVTPRWPEVPTANACYTSPSVHSTRYGNSSDMYTPLTTRRNSEYEHMQHFPGFAYINGEASTGWAK", "length": 641, "header": "tr|A0A0G2K3G6-1|A0A0G2K8F2_RAT Computationally mapped isoform of Regulatory factor X4 OS=Rattus norvegicus OX=10116 GN=Rfx4 PE=4 SV=2 CANONICAL=A0A0G2K8F2-1" }, "locus": { "chromosome": "7", "start_pos": 18927013, "end_pos": 18854388, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000084955.2", "url": "https://www.ensembl.org/id/ENSRNOT00000084955.2" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000072631.2", "url": "https://www.ensembl.org/id/ENSRNOP00000072631.2" } ] } }, { "isoform_ac": "A0A0G2K8F2-1", "url": "", "sequence": { "sequence": "MHCGLLEEPDMDSTESWIERCLNESENKRYSSHTSLGNVSNDENEEKENNRASKPHSTPATLQWLEENYEIAEGVCIPRSALYMHYLDFCEKNDTQPVNAASFGKIIRQQFPQLTTRRLGTRGQSKYHYYGIAVKESSQYYDVMYSKKGAAWVSETGKREVTKQTVAYSPRSKLGTLLPDFPNVKDLNLPASLPEEKVSTFIMMYRTHCQRILDTVIRANFDEVQSFLLHFWQGMPPHMLPVLGSSTVVNIVGVCDSILYKAISGVLMPTVLQALPDSLTQVIRKFAKQLDEWLKVALHDLPENLRNIKFELSRRFSQILRRQTSLNHLCQASRTVIHSADITFQMLEDWRNVDLSSITKQTLYTMEDSRDEHRRLIIQLYQEFDHLLEEQSPIESYIEWLDTMVDRCVVKVAAKRQGSLKKVAQQFLLMWSCFGTRVIRDMTLHSAPSFGSFHLIHLMFDDYVLYLLESLHCQERANELMRAMKGEGSTAEAQEEIILTEATPPTPSPGPSFSPAKSATSVEVPPPSSPVSNPSPEYTGLSTTGAMQSYTWSLTYTVTTAAGSPAENSQQLPCMRSTHVPSSSVTHRIPVYSHREEHGYTGSYNYGSYGNQHPHPLQNQYPALPHDTAISGPLHYSPYHRSSAQYPFNSPTSRMEPCLMSSTPRLHPTPVTPRWPEVPTANACYTSPSVHSTRYGNSSDMYTPLTTRRNSEYEHMQHFPGFAYINGEASTGWAK", "length": 735, "header": "tr|A0A0G2K8F2-1|A0A0G2K8F2_RAT Isoform 1 of Regulatory factor X4 OS=Rattus norvegicus OX=10116 GN=Rfx4 PE=4 SV=2 CANONICAL=A0A0G2K8F2-1" }, "locus": { "chromosome": "7", "start_pos": 19014967, "end_pos": 18854388, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000091571.2", "url": "https://www.ensembl.org/id/ENSRNOT00000091571.2" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000074585.2", "url": "https://www.ensembl.org/id/ENSRNOP00000074585.2" } ] } }, { "isoform_ac": "A0A8I5XZT6-1", "url": "", "sequence": { "sequence": "MFYQSLGTLFGCPSRGPETLQDGKESWIERCLNESENKRYSSHTSLGNVSNDENEEKENNRASKPHSTPATLQWLEENYEIAEGVCIPRSALYMHYLDFCEKNDTQPVNAASFGKIIRQQFPQLTTRRLGTRGQSKYHYYGIAVKESSQYYDVMYSKKGAAWVSETGKREVTKQTVAYSPRSKLGTLLPDFPNVKDLNLPASLPEEKVSTFIMMYRTHCQRILDTVIRANFDEVQSFLLHFWQGMPPHMLPVLGSSTVVNIVGVCDSILYKAISGVLMPTVLQALPDSLTQVIRKFAKQLDEWLKVALHDLPENLRNIKFELSRRFSQILRRQTSLNHLCQASRTVIHSADITFQMLEDWRNVDLSSITKQTLYTMEDSRDEHRRLIIQLYQEFDHLLEEQSPIESYIEWLDTMVDRCVVKVAAKRQGSLKKVAQQFLLMWSCFGTRVIRDMTLHSAPSFGSFHLIHLMFDDYVLYLLESLHCQERANELMRAMKGEGSTAEAQEEIILTEATPPTPSPGPSFSPAKSATSVEVPPPSSPVSNPSPEYTGLSTTGAMQSYTWSLTYTVTTAAGSPAENSQQLPCMRSTHVPSSSVTHRIPVYSHREEHGYTGSYNYGSYGNQHPHPLQNQYPALPHDTAISGPLHYSPYHRSSAQYPFNSPTSRMEPCLMSSTPRLHPTPVTPRWPEVPTANACYTSPSVHSTRYGNSSDMYTPLTTRRNSEYEHMQHFPGFAYINGEASTGWAK", "length": 745, "header": "tr|A0A8I5XZT6-1|A0A0G2K8F2_RAT Computationally mapped isoform of Regulatory factor X4 OS=Rattus norvegicus OX=10116 GN=Rfx4 PE=4 SV=1 CANONICAL=A0A0G2K8F2-1" }, "locus": { "chromosome": "7", "start_pos": 19009450, "end_pos": 18854388, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000114082.1", "url": "https://www.ensembl.org/id/ENSRNOT00000114082.1" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000076359.1", "url": "https://www.ensembl.org/id/ENSRNOP00000076359.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning", "id": "GO:0021914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021914", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K8F2", "url": "https://www.uniprot.org/uniprot/A0A0G2K8F2" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K8F2", "url": "https://www.uniprot.org/uniprot/A0A0G2K8F2" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K8F2", "url": "https://www.uniprot.org/uniprot/A0A0G2K8F2" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K8F2", "url": "https://www.uniprot.org/uniprot/A0A0G2K8F2" } ], "pmid": "" }, { "name": "telencephalon development", "id": "GO:0021537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021537", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K8F2", "url": "https://www.uniprot.org/uniprot/A0A0G2K8F2" } ], "pmid": "" }, { "name": "regulation of protein processing", "id": "GO:0070613", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070613", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K8F2", "url": "https://www.uniprot.org/uniprot/A0A0G2K8F2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K8F2", "url": "https://www.uniprot.org/uniprot/A0A0G2K8F2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K8F2", "url": "https://www.uniprot.org/uniprot/A0A0G2K8F2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K8F2", "url": "https://www.uniprot.org/uniprot/A0A0G2K8F2" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K8F2", "url": "https://www.uniprot.org/uniprot/A0A0G2K8F2" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K8F2", "url": "https://www.uniprot.org/uniprot/A0A0G2K8F2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 23, "end_pos": 25, "annotation": "n_glycosylation_sequon" }, { "start_pos": 38, "end_pos": 40, "annotation": "n_glycosylation_sequon" }, { "start_pos": 697, "end_pos": 699, "annotation": "n_glycosylation_sequon" }, { "start_pos": 93, "end_pos": 95, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "synthesized_glycans": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }