{
    "uniprot_canonical_ac": "A0A0G2K6P2-1",
    "uniprot_ac": "A0A0G2K6P2",
    "uniprot_id": "A0A0G2K6P2_RAT",
    "mass": {
        "chemical_mass": 98647.0,
        "monoisotopic_mass": 98647.0
    },
    "refseq": {
        "ac": "NP_001002822",
        "name": "coiled-coil alpha-helical rod protein 1",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001002822"
    },
    "gene_names": [
        {
            "name": "Cchcr1",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K6P2",
            "id": "A0A0G2K6P2"
        },
        {
            "name": "C6orf18; Hcr",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001002822",
            "id": "NP_001002822"
        },
        {
            "name": "Cchcr1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001002822",
            "id": "NP_001002822"
        },
        {
            "name": "Hcr",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K6P2",
            "id": "A0A0G2K6P2"
        }
    ],
    "protein_names": [
        {
            "name": "Coiled-coil alpha-helical rod protein 1",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "A0A0G2K6P2"
        },
        {
            "name": "Alpha-helical coiled-coil rod protein",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "A0A0G2K6P2"
        },
        {
            "name": "HCR (a-helix coiled-coil rod homolog)",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001002822",
            "id": "NP_001002822"
        },
        {
            "name": "coiled-coil alpha-helical rod protein 1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001002822",
            "id": "NP_001002822"
        }
    ],
    "function": [
        {
            "annotation": "May be a regulator of keratinocyte proliferation or differentiation.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A0G2K6P2",
                    "url": "https://www.uniprot.org/uniprot/A0A0G2K6P2#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "ARBA00003936",
                    "url": "https://www.uniprot.org/uniprot/ARBA00003936#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "M0RC14",
                    "url": "https://www.uniprot.org/uniprot/M0RC14#function"
                }
            ]
        }
    ],
    "disease": [
        {
            "disease_id": "DOID:986",
            "recommended_name": {
                "id": "DOID:986",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:986",
                "name": "alopecia areata",
                "description": "An autoimmune disease resulting in the loss of hair on the scalp and elsewhere on the body initially causing bald spots."
            },
            "synonyms": [
                {
                    "id": "DOID:986",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:986",
                    "name": "Circumscribed alopecia",
                    "description": ""
                },
                {
                    "id": "MONDO:0007082",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007082",
                    "name": "alopecia areata 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0007082",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007082",
                    "name": "alopecia areata 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0007082",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007082",
                    "name": "AA1",
                    "description": ""
                },
                {
                    "id": "MONDO:0007082",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007082",
                    "name": "alopecia universalis",
                    "description": ""
                },
                {
                    "id": "MONDO:0012551",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012551",
                    "name": "alopecia areata 2",
                    "description": ""
                },
                {
                    "id": "MONDO:0012551",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012551",
                    "name": "AA2",
                    "description": ""
                },
                {
                    "id": "MONDO:0012551",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0012551",
                    "name": "alopecia areata 2",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "986",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:986"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A0G2K6P2",
                    "url": "https://www.uniprot.org/uniprot/A0A0G2K6P2"
                }
            ],
            "common_name": "Rat"
        }
    ],
    "gene": [
        {
            "name": "Cchcr1",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K6P2",
            "locus": {
                "chromosome": "20",
                "start_pos": 3205676,
                "end_pos": 3218308,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSRNOG00000050233",
                        "url": "https://www.ensembl.org/id/ENSRNOG00000050233"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSRNOG00000050233",
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000050233",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "406196",
            "url": "https://www.ncbi.nlm.nih.gov/gene/406196",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR009800",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR009800",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "rno:406196",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:406196",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "CFANRRV",
            "url": "https://omabrowser.org/oma/group/CFANRRV/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR46822",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46822",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR46822:SF1",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46822:SF1",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF07111",
            "url": "http://pfam.xfam.org/family/PF07111",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "NP_001002822",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001002822",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "1302992",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1302992",
            "database": "RGD",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "A0A0G2K6P2",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K6P2",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A0G2K6P2-1",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K6P2-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "M0RC14",
            "url": "https://www.uniprot.org/uniprot/M0RC14",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "M0RC14-1",
            "url": "https://www.uniprot.org/uniprot/M0RC14-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MWPHSSGARPWANPLIGNDPEIVTRWCLDGLPNGPTIPWRGLWRLGSLYCVQRVLSCRDRRHLRRKGNIGDWRQELEDSYNGEMLPPSGFDGLVPPSHFQARPLSTLPRMASTWASNVPLVQSPPGQDVLERRLDTQRSTVTMWGQDFCGDRQGLGRRGRSLELGVSGALSQQAELISRQLQELRLLEEEVRTLRETSLQQKMRLESQAVELDALAVAEKAGQAEAEGLRTALAGAEMVRKNLEEAKQKELEEIQSLHQEQLSSLTQAHQKALDSLTSKAEDLEKSLNSLEMKQAGEAKQLTMAQKEAELLRNQLSKTQEELEAQVTLVENLRKYVGEQVPPEVPSQARELEQKELLDTLKHLKEDRTNLQATVELLQVRVQSLTHMLALQEEELTRKIHPLDPLEPEFPKKCRSLLRGWREKVFALMVQLKAQDLQHRDSTKQLRDQVAELQEQVTAQSQEQAILQRALQDKTAQVEVERMSTKTLKMELSQAQEARWRQEQQAASAEEQLKFVVSAMNSTQARLQSTMTRVDQAVARIPSLCNRLSYAVRKVHTIKGLMARKLALVQLRLESCPPPEPAPPPDTDLSLELEQLREERNRLDAELQLSAHLIQQEVGRVREQGEAEHRHLTEVAQQLEQELQRAQESLASVGQQLEAARQGQQESTEEAASLRQELTQQQEIYGQALQEKVAEVESRLREQLSDTKRRLNEARREQAKAVVSLRQIQHKATLEKERNQELRRLQDEARKEEGQRLTRRVQELERDKNLMLATLKQEGLLSRYKQQRLLAVLPSGVSKKCSSQPVEPPESAAASPCKESMKGSLTVLLDNLQGLSEAISRDDAICLEDNQNTKSPPSNPLLGRSCQEEE",
        "length": 869,
        "header": "tr|A0A0G2K6P2-1|A0A0G2K6P2_RAT Isoform 1 of Coiled-coil alpha-helical rod protein 1  OS=Rattus norvegicus OX=10116 GN=Cchcr1 PE=4 SV=2 CANONICAL=A0A0G2K6P2-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A0G2K6P2-1",
            "url": "",
            "sequence": {
                "sequence": "MWPHSSGARPWANPLIGNDPEIVTRWCLDGLPNGPTIPWRGLWRLGSLYCVQRVLSCRDRRHLRRKGNIGDWRQELEDSYNGEMLPPSGFDGLVPPSHFQARPLSTLPRMASTWASNVPLVQSPPGQDVLERRLDTQRSTVTMWGQDFCGDRQGLGRRGRSLELGVSGALSQQAELISRQLQELRLLEEEVRTLRETSLQQKMRLESQAVELDALAVAEKAGQAEAEGLRTALAGAEMVRKNLEEAKQKELEEIQSLHQEQLSSLTQAHQKALDSLTSKAEDLEKSLNSLEMKQAGEAKQLTMAQKEAELLRNQLSKTQEELEAQVTLVENLRKYVGEQVPPEVPSQARELEQKELLDTLKHLKEDRTNLQATVELLQVRVQSLTHMLALQEEELTRKIHPLDPLEPEFPKKCRSLLRGWREKVFALMVQLKAQDLQHRDSTKQLRDQVAELQEQVTAQSQEQAILQRALQDKTAQVEVERMSTKTLKMELSQAQEARWRQEQQAASAEEQLKFVVSAMNSTQARLQSTMTRVDQAVARIPSLCNRLSYAVRKVHTIKGLMARKLALVQLRLESCPPPEPAPPPDTDLSLELEQLREERNRLDAELQLSAHLIQQEVGRVREQGEAEHRHLTEVAQQLEQELQRAQESLASVGQQLEAARQGQQESTEEAASLRQELTQQQEIYGQALQEKVAEVESRLREQLSDTKRRLNEARREQAKAVVSLRQIQHKATLEKERNQELRRLQDEARKEEGQRLTRRVQELERDKNLMLATLKQEGLLSRYKQQRLLAVLPSGVSKKCSSQPVEPPESAAASPCKESMKGSLTVLLDNLQGLSEAISRDDAICLEDNQNTKSPPSNPLLGRSCQEEE",
                "length": 869,
                "header": "tr|A0A0G2K6P2-1|A0A0G2K6P2_RAT Isoform 1 of Coiled-coil alpha-helical rod protein 1  OS=Rattus norvegicus OX=10116 GN=Cchcr1 PE=4 SV=2 CANONICAL=A0A0G2K6P2-1"
            },
            "locus": {
                "chromosome": "20",
                "start_pos": 3217767,
                "end_pos": 3205821,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000084918.2",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000084918.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000073888.2",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000073888.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "M0RC14-1",
            "url": "",
            "sequence": {
                "sequence": "MRLESQAVELDALAVAEKAGQAEAEGLRTALAGAEMVRKNLEEAKQKELEEIQSLHQEQLSSLTQAHQKALDSLTSKAEDLEKSLNSLEMKQAGEAKQLTMAQKEAELLRNQLSKTQEELEAQVTLVENLRKYVGEQVPPEVPSQARELEQKELLDTLKHLKEDRTNLQATVELLQVRVQSLTHMLALQEEELTRKIHPLDPLEPEFPKKCRSLLRGWREKVFALMVQLKAQDLQHRDSTKQLRDQVAELQEQVTAQSQEQAILQRALQDKTAQVEVERMSTKTLKMELSQAQEARWRQEQQAASAEEQLKFVVSAMNSTQARLQSTMTRVDQAVARIPSLCNRLSYAVRKVHTIKGLMARKLALVQLRLESCPPPEPAPPPDTDLSLELEQLREERNRLDAELQLSAHLIQQEVGRVREQGEAEHRHLTEVAQQLEQELQRAQESLASVGQQLEAARQGQQESTEEAASLRQELTQQQEIYGQALQEKVAEVESRLREQLSDTKRRLNEARREQAKADPTQSHSGKGAESGAQAPAGRGPEGRRAAADTASAGAGEGQEPHAGHLEARGSPLPLQAAAPVSSASLGSE",
                "length": 589,
                "header": "tr|M0RC14-1|M0RC14_RAT Computationally mapped isoform of Coiled-coil alpha-helical rod protein 1  OS=Rattus norvegicus OX=10116 GN=Cchcr1 PE=4 SV=3 CANONICAL=A0A0G2K6P2-1"
            },
            "locus": {
                "chromosome": "20",
                "start_pos": 3214544,
                "end_pos": 3206199,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000074049.3",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000074049.3"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000067117.3",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000067117.3"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [
        {
            "id": "rno:406196",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:406196",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q8K2I2-1",
            "protein_name": "Coiled-coil alpha-helical rod protein 1",
            "gene_name": "Cchcr1",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MLPPSGFAGLVPPSHFQARPLPTLPRMAPTWASDVPLVQSPASQDVLERRLDAQRSTVTTWGQDFCGDGQGLGRRGRSLELGFSSALSQQAELISRQLQELRRLEEEVRSLRETSLQQKMRLETQAVELDALAVAEKAGQAEAEGLRTALAGAEMVRKNLEEAKHKELEEIQSLHQEQLSSLTQAHQKALDSLASKAEGLEKSLNSLETKRAGEAKQLAMAQKEADMLRNQLSKTQEELEAQVTLVESLRKYVGEQVLPEFPSQEWELERKELLDTLKHLKEDRADLQATVELLQVRVQSLTHMLALQEEELTRKIQPLDPLEPEFPKKCRSLLRNWREKVFALMVQLKAQDLQHRDSTSQLRIQVAELQEQVTSQSQEQAILQRALQDKTAQVEVERMSTKSLQMELDQAQEARRRQEQQIASAEEQLKFVVGAMNSTQAKLQSTMTRMDQAVARIPSLSNRLSYAVRKVHTIKGLMARKVALAQLRVESSPPSEAAPPLDTDLSVELEQLREERNRLDAELQLSAHLIQQEVGRAREQGEVERRRLIEVAQQLEQELQRAQESLASVGQQLEAARRGQQESTEEAASLRQELTQQQEIYGQALQEKVAEVETRLREQLSDTKRRLNEARREQAKAVVSLRQIQHKATQEKERNQELRRLQDEARKEEGQRLTRRVQELERDKNLMLQRLLAVLPSGVNKKCSPRSVESSSSESPAAASCKESVKGSLTVLLDNLQGLSEAISRDEDICVEDNQNTKKTKNPPSDPLLS",
                "length": 770
            },
            "evidence": [
                {
                    "id": "45230985",
                    "url": "http://www.informatics.jax.org/homology/45230985",
                    "database": "MGI"
                }
            ],
            "common_name": "Mouse"
        },
        {
            "uniprot_canonical_ac": "Q8TD31-1",
            "protein_name": "Coiled-coil alpha-helical rod protein 1",
            "gene_name": "CCHCR1",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MFPPSGSTGLIPPSHFQARPLSTLPRMAPTWLSDIPLVQPPGHQDVSERRLDTQRPQVTMWERDVSSDRQEPGRRGRSWGLEGSQALSQQAEVIVRQLQELRRLEEEVRLLRETSLQQKMRLEAQAMELEALARAEKAGRAEAEGLRAALAGAEVVRKNLEEGSQRELEEVQRLHQEQLSSLTQAHEEALSSLTSKAEGLEKSLSSLETRRAGEAKELAEAQREAELLRKQLSKTQEDLEAQVTLVENLRKYVGEQVPSEVHSQTWELERQKLLETMQHLQEDRDSLHATAELLQVRVQSLTHILALQEEELTRKVQPSDSLEPEFTRKCQSLLNRWREKVFALMVQLKAQELEHSDSVKQLKGQVASLQEKVTSQSQEQAILQRSLQDKAAEVEVERMGAKGLQLELSRAQEARRRWQQQTASAEEQLRLVVNAVSSSQIWLETTMAKVEGAAAQLPSLNNRLSYAVRKVHTIRGLIARKLALAQLRQESCPLPPPVTDVSLELQQLREERNRLDAELQLSARLIQQEVGRAREQGEAERQQLSKVAQQLEQELQQTQESLASLGLQLEVARQGQQESTEEAASLRQELTQQQELYGQALQEKVAEVETRLREQLSDTERRLNEARREHAKAVVSLRQIQRRAAQEKERSQELRRLQEEARKEEGQRLARRLQELERDKNLMLATLQQEGLLSRYKQQRLLTVLPSLLDKKKSVVSSPRPPECSASAPVAAAVPTRESIKGSLSVLLDDLQDLSEAISKEEAVCQGDNLDRCSSSNPQMSS",
                "length": 782
            },
            "evidence": [
                {
                    "id": "45230985",
                    "url": "http://www.informatics.jax.org/homology/45230985",
                    "database": "MGI"
                }
            ],
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Cellular Component",
                "total": 4,
                "go_terms": [
                    {
                        "name": "nucleus",
                        "id": "GO:0005634",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K6P2",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K6P2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cytoplasm",
                        "id": "GO:0005737",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K6P2",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K6P2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cytosol",
                        "id": "GO:0005829",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K6P2",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K6P2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "centriole",
                        "id": "GO:0005814",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K6P2",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K6P2"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 2,
                "go_terms": [
                    {
                        "name": "cell differentiation",
                        "id": "GO:0030154",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K6P2",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K6P2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "protein export from nucleus",
                        "id": "GO:0006611",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006611",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K6P2",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K6P2"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 520,
            "end_pos": 522,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
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