{ "uniprot_canonical_ac": "A0A0G2K665-1", "uniprot_ac": "A0A0G2K665", "uniprot_id": "A0A0G2K665_RAT", "mass": { "chemical_mass": 157602.0, "monoisotopic_mass": 157602.0 }, "refseq": {}, "gene_names": [ { "name": "Tgap1", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A0A0G2K665", "id": "A0A0G2K665" }, { "name": "tGap1", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A0A0G2K665", "id": "A0A0G2K665" } ], "protein_names": [ { "name": "GTPase activating protein testicular GAP1", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "A0A0G2K665" } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K665", "url": "https://www.uniprot.org/uniprot/A0A0G2K665" } ], "common_name": "Rat" } ], "gene": [ { "name": "Tgap1", "url": "https://www.uniprot.org/uniprot/A0A0G2K665", "locus": {} } ], "crossref": [ { "id": "ENSRNOG00000022511", "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000022511", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04402", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04402", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "25690at2759", "url": "http://www.orthodb.org/?query=25690at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "2964977at2759", "url": "http://www.orthodb.org/?query=2964977at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23179", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23179", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23179:SF39", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23179:SF39", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00620", "url": "http://pfam.xfam.org/family/PF00620", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "XP_006232196", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006232196", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "1359558", "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1359558", "database": "RGD", "categories": [ "Organism-specific" ] }, { "id": "A0A0G2K665", "url": "https://www.uniprot.org/uniprot/A0A0G2K665", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0G2K665-1", "url": "https://www.uniprot.org/uniprot/A0A0G2K665-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3V905", "url": "https://www.uniprot.org/uniprot/G3V905", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3V905-1", "url": "https://www.uniprot.org/uniprot/G3V905-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDMTEEEDVGEENRTVVCQGAVVIRRGWMRKKRYLTLFNDVLVISSKLNKKKFKIKHVIPLTYLWVGDEVDAFRSDNTAASKSIYLYWPMGHVVATFRSMEQTIWWYFFLQRSIREAKKHNKIEIPMQIFTEDIACCDTPLYVTATNFDTVNDIISKLLPMIRKHNTEDYQLWFCPGPGKAPRLLQGHEYPHDIRMINIQKNFSSRDLRNFTAVPSLPGVIMKYLNADVHGKFILKPRNSTRSQQQKNMKEKTFKKQRTSITSWLDRGSVPHQDKVCTIPQVKKGGKLFGRELSSICQDGDLPSAILDMLYLLKKEGPTTKGVFIEPPSTTLFQTVKDKLDSGEEVDIEKQSVHVVAWIFKDFLQNIEGSLMTSKLYDEWIAVTEKVNDEEKLVAVQSLLDKMPPENAALLRQLFRILYEIKNNSAVNEMSSYHLSVGLAPCLLFVPSSCNNGMTNDISKKISLVKFMIENSPQFFGEDLAAVWHGASLYHRPGAKSLCPQSTPTNSGNVKETKHGLSSSPSGRTCTPGYNTLRRRSAALLPHEGIIDSQKHEVNVYTKPTVPSLNPPQAKQKCLFGKSLTSLFEDKKLPTPILDMLSIIAEKGHESDHIFKILPKESHWSLRYRLDSEQHIDWDEECVLVIASVLKDFIINIDGSLLTLEFYENWLSIPDEGTLAEKINAIQSLLQQIPEPNFILLKHLVYVLVIIKDSSMNNLDSYRLSLRIAPHVLWGKTSRDSLFGTDVLRKLSIMQIMIDNYHEIFGNDDMFIKHTDKESNDLRMNEESKSSSDKSPVMTNVIACCTGTTCDNNEKLNISCAALQEEGPPEKCEDNEYSNPPVRCLFPLRPAKKCLFGQPLTSIFEDKKIPTPIFDMLSIIAEKGKDTDHIFKTLSEYSHWSLRDKIDTYQYINWNEERVLVIASVLKDFITHIDGSLLTCELYESWLSVPDEGTLAEQINAIQRLLQKIPEPNFILLKHLICVLVIIKDSSTNKLDTNRLSLRLGPHLLWGWTSSDAFFGKNVSRKLSIIQIMIDNYHQIFGNDDMFIKHTDKESDDLKMNEESKSSSDKSPVMTNVIACCTGTTCDKNEKFNISYAALQVAGPTEKQKSNIYTKPPEYSNPTPSRKKCLFGKNLTSIYVDSKLPAPILEMLSIIAEKGKESDQIFAILPENSHWSLRERIESEELIDWNEEGILVIASVLKDFITNIEGSLLTSDLYESWLSVPDEGTLAGKINAIQRLLLKIPQANFILLKHLICVLVKIRDSSMNNLDSNNLSVRIAPYVLWNQTPKDTLFGSDVSRKMSIIQIMIDNYSQIFGNDSIFCKGIDKRPEDLKTCPDSINASGKSPIMNEFLGGRNRKTYDNSENFKISSIALQEEGPTGQDTKTATYKW", "length": 1387, "header": "tr|A0A0G2K665-1|A0A0G2K665_RAT Isoform 1 of GTPase activating protein testicular GAP1 OS=Rattus norvegicus OX=10116 GN=Tgap1 PE=1 SV=1 CANONICAL=A0A0G2K665-1" }, "isoforms": [ { "isoform_ac": "A0A0G2K665-1", "url": "", "sequence": { "sequence": "MDMTEEEDVGEENRTVVCQGAVVIRRGWMRKKRYLTLFNDVLVISSKLNKKKFKIKHVIPLTYLWVGDEVDAFRSDNTAASKSIYLYWPMGHVVATFRSMEQTIWWYFFLQRSIREAKKHNKIEIPMQIFTEDIACCDTPLYVTATNFDTVNDIISKLLPMIRKHNTEDYQLWFCPGPGKAPRLLQGHEYPHDIRMINIQKNFSSRDLRNFTAVPSLPGVIMKYLNADVHGKFILKPRNSTRSQQQKNMKEKTFKKQRTSITSWLDRGSVPHQDKVCTIPQVKKGGKLFGRELSSICQDGDLPSAILDMLYLLKKEGPTTKGVFIEPPSTTLFQTVKDKLDSGEEVDIEKQSVHVVAWIFKDFLQNIEGSLMTSKLYDEWIAVTEKVNDEEKLVAVQSLLDKMPPENAALLRQLFRILYEIKNNSAVNEMSSYHLSVGLAPCLLFVPSSCNNGMTNDISKKISLVKFMIENSPQFFGEDLAAVWHGASLYHRPGAKSLCPQSTPTNSGNVKETKHGLSSSPSGRTCTPGYNTLRRRSAALLPHEGIIDSQKHEVNVYTKPTVPSLNPPQAKQKCLFGKSLTSLFEDKKLPTPILDMLSIIAEKGHESDHIFKILPKESHWSLRYRLDSEQHIDWDEECVLVIASVLKDFIINIDGSLLTLEFYENWLSIPDEGTLAEKINAIQSLLQQIPEPNFILLKHLVYVLVIIKDSSMNNLDSYRLSLRIAPHVLWGKTSRDSLFGTDVLRKLSIMQIMIDNYHEIFGNDDMFIKHTDKESNDLRMNEESKSSSDKSPVMTNVIACCTGTTCDNNEKLNISCAALQEEGPPEKCEDNEYSNPPVRCLFPLRPAKKCLFGQPLTSIFEDKKIPTPIFDMLSIIAEKGKDTDHIFKTLSEYSHWSLRDKIDTYQYINWNEERVLVIASVLKDFITHIDGSLLTCELYESWLSVPDEGTLAEQINAIQRLLQKIPEPNFILLKHLICVLVIIKDSSTNKLDTNRLSLRLGPHLLWGWTSSDAFFGKNVSRKLSIIQIMIDNYHQIFGNDDMFIKHTDKESDDLKMNEESKSSSDKSPVMTNVIACCTGTTCDKNEKFNISYAALQVAGPTEKQKSNIYTKPPEYSNPTPSRKKCLFGKNLTSIYVDSKLPAPILEMLSIIAEKGKESDQIFAILPENSHWSLRERIESEELIDWNEEGILVIASVLKDFITNIEGSLLTSDLYESWLSVPDEGTLAGKINAIQRLLLKIPQANFILLKHLICVLVKIRDSSMNNLDSNNLSVRIAPYVLWNQTPKDTLFGSDVSRKMSIIQIMIDNYSQIFGNDSIFCKGIDKRPEDLKTCPDSINASGKSPIMNEFLGGRNRKTYDNSENFKISSIALQEEGPTGQDTKTATYKW", "length": 1387, "header": "tr|A0A0G2K665-1|A0A0G2K665_RAT Isoform 1 of GTPase activating protein testicular GAP1 OS=Rattus norvegicus OX=10116 GN=Tgap1 PE=1 SV=1 CANONICAL=A0A0G2K665-1" }, "locus": { "chromosome": "2", "start_pos": 90436231, "end_pos": 90374660, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000082912.2", "url": "https://www.ensembl.org/id/ENSRNOT00000082912.2" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000073694.1", "url": "https://www.ensembl.org/id/ENSRNOP00000073694.1" } ] } }, { "isoform_ac": "G3V905-1", "url": "", "sequence": { "sequence": "MEQTIWWYFFLQRSIREAKKHNKIEIPMQIFTEDIACCDTPLYVTATNFDTVNDIISKLLPMIRKHNTEDYQLWFCPGPGKAPRLLQGHEYPHDIRMINIQKNFSSRDLRNFTAVPSLPGVIMKYLNADVHGKFILKPRNSTRSQQQKNMKEKTFKKQRTSITSWLDRGSVPHQDKVCTIPQVKKGGKLFGRELSSICQDGDLPSAILDMLYLLKKEGPTTKGVFIEPPSTTLFQTVKDKLDSGEEVDIEKQSVHVVAWIFKDFLQNIEGSLMTSKLYDEWIAVTEKVNDEEKLVAVQSLLDKMPPENAALLRQLFRILYEIKNNSAVNEMSSYHLSVGLAPCLLFVPSSCNNGMTNDISKKISLVKFMIENSPQFFGEDLAAVWHGASLYHRPGAKSLCPQSTPTNSGNVKETKHGLSSSPSGRTCTPGYNTLRRRSAALLPHEGIIDSQKHEVNVYTKPTVPSLNPPQAKQKCLFGKSLTSLFEDKKLPTPILDMLSIIAEKGHESDHIFKILPKESHWSLRYRLDSEQHIDWDEECVLVIASVLKDFIINIDGSLLTLEFYENWLSIPDEGTLAEKINAIQSLLQQIPEPNFILLKHLVYVLVIIKDSSMNNLDSYRLSLRIAPHVLWGKTSRDSLFGTDVLRKLSIMQIMIDNYHEIFGNDDMFIKHTDKESNDLRMNEESKSSSDKSPVMTNVIACCTGTTCDNNEKLNISCAALQEEGPPEKCEDNEYSNPPVRCLFPLRPAKKCLFGQPLTSIFEDKKIPTPIFDMLSIIAEKGKDTDHIFKTLSEYSHWSLRDKIDTYQYINWNEERVLVIASVLKDFITHIDGSLLTCELYESWLSVPDEGTLAEQINAIQRLLQKIPEPNFILLKHLICVLVIIKDSSTNKLDTNRLSLRLGPHLLWGWTSSDAFFGKNVSRKLSIIQIMIDNYHQIFGNDDMFIKHTDKESDDLKMNEESKSSSDKSPVMTNVIACCTGTTCDKNEKFNISYAALQVAGPTEKQKSNIYTKPPEYSNPTPSRKKCLFGKNLTSIYVDSKLPAPILEMLSIIAEKGKESDQIFAILPENSHWSLRERIESEELIDWNEEGILVIASVLKDFITNIEGSLLTSDLYESWLSVPDEGTLAGKINAIQRLLLKIPQANFILLKHLICVLVKIRDSSMNNLDSNNLSVRIAPYVLWNQTPKDTLFGSDVSRKMSIIQIMIDNYSQIFGNDSIFCKGIDKRPEDLKTCPDSINASGKSPIMNEFLGGRNRKTYDNSENFKISSIALQEEGPTGQDTKTATYKW", "length": 1288, "header": "tr|G3V905-1|G3V905_RAT Computationally mapped isoform of GTPase activating protein testicular GAP1 OS=Rattus norvegicus OX=10116 GN=Tgap1 PE=1 SV=1 CANONICAL=A0A0G2K665-1" }, "locus": { "chromosome": "2", "start_pos": 90436231, "end_pos": 90380868, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000033404.8", "url": "https://www.ensembl.org/id/ENSRNOT00000033404.8" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000032200.4", "url": "https://www.ensembl.org/id/ENSRNOP00000032200.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K665", "url": "https://www.uniprot.org/uniprot/A0A0G2K665" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K665", "url": "https://www.uniprot.org/uniprot/A0A0G2K665" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1018, "end_pos": 1020, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1089, "end_pos": 1091, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1130, "end_pos": 1132, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1270, "end_pos": 1272, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1282, "end_pos": 1284, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1307, "end_pos": 1309, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1314, "end_pos": 1316, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1337, "end_pos": 1339, "annotation": "n_glycosylation_sequon" }, { "start_pos": 13, "end_pos": 15, "annotation": "n_glycosylation_sequon" }, { "start_pos": 202, "end_pos": 204, "annotation": "n_glycosylation_sequon" }, { "start_pos": 210, "end_pos": 212, "annotation": "n_glycosylation_sequon" }, { "start_pos": 239, "end_pos": 241, "annotation": "n_glycosylation_sequon" }, { "start_pos": 423, "end_pos": 425, "annotation": "n_glycosylation_sequon" }, { "start_pos": 813, "end_pos": 815, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "synthesized_glycans": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }