{
    "uniprot_canonical_ac": "A0A0G2K654-1",
    "uniprot_ac": "A0A0G2K654",
    "uniprot_id": "A0A0G2K654_RAT",
    "mass": {
        "chemical_mass": 21317.0,
        "monoisotopic_mass": 21317.0
    },
    "refseq": {},
    "gene_names": [
        {
            "name": "H1f2",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K654",
            "id": "A0A0G2K654"
        }
    ],
    "protein_names": [
        {
            "name": "H1.2 linker histone, cluster member",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "A0A0G2K654"
        }
    ],
    "function": [],
    "disease": [
        {
            "disease_id": "DOID:9952",
            "recommended_name": {
                "id": "DOID:9952",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:9952",
                "name": "acute lymphoblastic leukemia",
                "description": "A acute leukemia that is characterized by over production of lymphoblasts."
            },
            "synonyms": [
                {
                    "id": "DOID:9952",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:9952",
                    "name": "ALL",
                    "description": ""
                },
                {
                    "id": "DOID:9952",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:9952",
                    "name": "precursor lymphoblastic lymphoma/leukemia",
                    "description": ""
                },
                {
                    "id": "DOID:9952",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:9952",
                    "name": "acute lymphoblastic leukaemia",
                    "description": ""
                },
                {
                    "id": "DOID:9952",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:9952",
                    "name": "acute lymphocytic leukaemia",
                    "description": ""
                },
                {
                    "id": "MONDO:0009539",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009539",
                    "name": "lymphoblastic leukemia, acute, with lymphomatous features",
                    "description": ""
                },
                {
                    "id": "MONDO:0009539",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009539",
                    "name": "leukemia, acute lymphoblastic",
                    "description": ""
                },
                {
                    "id": "MONDO:0009539",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009539",
                    "name": "lymphoblastic leukemia, acute, with lymphomatous features",
                    "description": ""
                },
                {
                    "id": "MONDO:0009539",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009539",
                    "name": "lall",
                    "description": ""
                },
                {
                    "id": "MONDO:0009539",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009539",
                    "name": "lymphomatous All",
                    "description": ""
                },
                {
                    "id": "MONDO:0013108",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013108",
                    "name": "leukemia, acute lymphocytic, susceptibility to, 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0013108",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013108",
                    "name": "T-cell acute lymphoblastic leukemia, somatic",
                    "description": ""
                },
                {
                    "id": "MONDO:0013108",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013108",
                    "name": "leukemia, T-cell acute lymphoblastic, somatic",
                    "description": ""
                },
                {
                    "id": "MONDO:0013108",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013108",
                    "name": "leukemia, T-cell acute lymphocytic, somatic",
                    "description": ""
                },
                {
                    "id": "MONDO:0013108",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013108",
                    "name": "leukemia, acute lymphoblastic, somatic",
                    "description": ""
                },
                {
                    "id": "MONDO:0013108",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013108",
                    "name": "leukemia, acute lymphocytic, Philadelphia chromosome positive, somatic",
                    "description": ""
                },
                {
                    "id": "MONDO:0013108",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013108",
                    "name": "leukemia, acute lymphocytic, susceptibility to, 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0013108",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013108",
                    "name": "ALL",
                    "description": ""
                },
                {
                    "id": "MONDO:0013108",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013108",
                    "name": "All1",
                    "description": ""
                },
                {
                    "id": "MONDO:0013108",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013108",
                    "name": "leukemia, B-cell acute lymphoblastic, susceptibility to",
                    "description": ""
                },
                {
                    "id": "MONDO:0013108",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013108",
                    "name": "leukemia, T-cell acute lymphoblastic, susceptibility to",
                    "description": ""
                },
                {
                    "id": "MONDO:0013108",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013108",
                    "name": "leukemia, acute lymphoblastic",
                    "description": ""
                },
                {
                    "id": "MONDO:0013108",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013108",
                    "name": "leukemia, acute lymphoblastic, B-Hyperdiploid, susceptibility to",
                    "description": ""
                },
                {
                    "id": "MONDO:0013108",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013108",
                    "name": "leukemia, acute lymphoblastic, susceptibility to, 1",
                    "description": ""
                },
                {
                    "id": "MIM:613065",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/613065",
                    "name": "Leukemia, acute lymphoblastic",
                    "description": "Leukemia, acute lymphoblastic"
                }
            ],
            "evidence": [
                {
                    "id": "9952",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:9952"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A0G2K654",
                    "url": "https://www.uniprot.org/uniprot/A0A0G2K654"
                }
            ],
            "common_name": "Rat"
        }
    ],
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        {
            "name": "H1f2",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K654",
            "locus": {
                "chromosome": "17",
                "start_pos": 41388477,
                "end_pos": 41392635,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSRNOG00000067441",
                        "url": "https://www.ensembl.org/id/ENSRNOG00000067441"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSRNOG00000054978",
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000054978",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "cd00073",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00073",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "684681",
            "url": "https://www.ncbi.nlm.nih.gov/gene/684681",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR005818",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR005818",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR005819",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR005819",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR036388",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR036390",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "rno:684681",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:684681",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "A0A0G2K654",
            "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A0A0G2K654",
            "database": "O-GlcNAc Database",
            "categories": [
                "Glycoproteomics"
            ]
        },
        {
            "id": "FPTGNRP",
            "url": "https://omabrowser.org/oma/group/FPTGNRP/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "5362469at2759",
            "url": "http://www.orthodb.org/?query=5362469at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00538",
            "url": "http://pfam.xfam.org/family/PF00538",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "XP_001071565",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001071565",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "1587893",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1587893",
            "database": "RGD",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "A0A0G2K654",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K654",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A0G2K654-1",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K654-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MSETAPAAPAAAPPAEKAPAKKKAAKKPAGMRRKASGPPVSELITKAVAASKERSGVSLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGILVQTKGTGASGSFKLNKKAASGEAKPKAKKAAAAKAKKPAGAAKKPKKATGAATPKKAAKKTPKKAKKPAAAAVTKKVAKSPKKAKVTKAKKVKSASKAVKPKAAKPKVAKAKKVAAKKK",
        "length": 212,
        "header": "tr|A0A0G2K654-1|A0A0G2K654_RAT Isoform 1 of H1.2 linker histone, cluster member  OS=Rattus norvegicus OX=10116 GN=H1f2 PE=3 SV=1 CANONICAL=A0A0G2K654-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A0G2K654-1",
            "url": "",
            "sequence": {
                "sequence": "MSETAPAAPAAAPPAEKAPAKKKAAKKPAGMRRKASGPPVSELITKAVAASKERSGVSLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGILVQTKGTGASGSFKLNKKAASGEAKPKAKKAAAAKAKKPAGAAKKPKKATGAATPKKAAKKTPKKAKKPAAAAVTKKVAKSPKKAKVTKAKKVKSASKAVKPKAAKPKVAKAKKVAAKKK",
                "length": 212,
                "header": "tr|A0A0G2K654-1|A0A0G2K654_RAT Isoform 1 of H1.2 linker histone, cluster member  OS=Rattus norvegicus OX=10116 GN=H1f2 PE=3 SV=1 CANONICAL=A0A0G2K654-1"
            },
            "locus": {
                "chromosome": "17",
                "start_pos": 41392555,
                "end_pos": 41391920,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000106787.1",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000106787.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000077080.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000077080.1"
                    }
                ]
            }
        }
    ],
    "glycosylation": [
        {
            "glytoucan_ac": "G49108TO",
            "type": "O-linked",
            "subtype": "O-GlcNAcylation",
            "site_category": "reported_with_glycan",
            "site_seq": "",
            "relation": "attached",
            "comment": "O-GlcNAcylation",
            "evidence": [
                {
                    "id": "A0A0G2K654",
                    "database": "O-GlcNAc Database",
                    "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A0A0G2K654"
                },
                {
                    "id": "34502162",
                    "database": "PubMed",
                    "url": "https://glygen.org/publication/PubMed/34502162"
                }
            ]
        }
    ],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [
        "glycoprotein",
        "glycoprotein_reported_with_glycan"
    ],
    "publication": [
        {
            "title": "An O-GlcNAcylomic Approach Reveals ACLY as a Potential Target in Sepsis in the Young Rat.",
            "journal": "International journal of molecular sciences",
            "date": "2021",
            "authors": "Denis M, Dupas T, Persello A, Dontaine J, Bultot L, Betus C, Pele T, Dhot J, Erraud A, Maillard A, Montnach J, Leroux AA, Bigot-Corbel E, Vertommen D, Riviere M, Lebreton J, Tessier A, Waard M, Bertrand L, Rozec B, Lauzier B",
            "evidence": [
                {
                    "database": "O-GlcNAc Database",
                    "id": "A0A0G2K654",
                    "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A0A0G2K654"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "34502162",
                    "url": "https://glygen.org/publication/PubMed/34502162"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "rno:684681",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:684681",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "P15864-1",
            "protein_name": "Histone H1.2",
            "gene_name": "H1-2",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MSEAAPAAPAAAPPAEKAPAKKKAAKKPAGVRRKASGPPVSELITKAVAASKERSGVSLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGILVQTKGTGASGSFKLNKKAASGEAKPQAKKAGAAKAKKPAGAAKKPKKATGAATPKKAAKKTPKKAKKPAAAAVTKKVAKSPKKAKVTKPKKVKSASKAVKPKAAKPKVAKAKKVAAKKK",
                "length": 212
            },
            "evidence": [
                {
                    "id": "45233545",
                    "url": "http://www.informatics.jax.org/homology/45233545",
                    "database": "MGI"
                }
            ],
            "common_name": "Mouse"
        },
        {
            "uniprot_canonical_ac": "P16403-1",
            "protein_name": "Histone H1.2",
            "gene_name": "H1-2",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MSETAPAAPAAAPPAEKAPVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKAKVAKPKKAAKSAAKAVKPKAAKPKVVKPKKAAPKKK",
                "length": 213
            },
            "evidence": [
                {
                    "id": "45233545",
                    "url": "http://www.informatics.jax.org/homology/45233545",
                    "database": "MGI"
                }
            ],
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Biological Process",
                "total": 8,
                "go_terms": [
                    {
                        "name": "negative regulation of transcription by RNA polymerase II",
                        "id": "GO:0000122",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K654",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K654"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "regulation of transcription by RNA polymerase II",
                        "id": "GO:0006357",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K654",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K654"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "chromatin organization",
                        "id": "GO:0006325",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K654",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K654"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "nucleosome assembly",
                        "id": "GO:0006334",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006334",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K654",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K654"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "chromosome condensation",
                        "id": "GO:0030261",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030261",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K654",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K654"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "histone H3-K4 trimethylation",
                        "id": "GO:0080182",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0080182",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K654",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K654"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "histone H3-K27 trimethylation",
                        "id": "GO:0098532",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098532",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K654",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K654"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "negative regulation of DNA recombination",
                        "id": "GO:0045910",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045910",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K654",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K654"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 5,
                "go_terms": [
                    {
                        "name": "DNA binding",
                        "id": "GO:0003677",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K654",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K654"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "double-stranded DNA binding",
                        "id": "GO:0003690",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003690",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K654",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K654"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "chromatin DNA binding",
                        "id": "GO:0031490",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031490",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K654",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K654"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "nucleosomal DNA binding",
                        "id": "GO:0031492",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031492",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K654",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K654"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "structural constituent of chromatin",
                        "id": "GO:0030527",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030527",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K654",
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                "name": "Cellular Component",
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            "end_pos": 78,
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    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
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    "synthesized_glycans": [],
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        {
            "name": "homologset.mgi",
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