{
    "uniprot_canonical_ac": "A0A0G2K528-1",
    "uniprot_ac": "A0A0G2K528",
    "uniprot_id": "A0A0G2K528_RAT",
    "mass": {
        "chemical_mass": 37161.0,
        "monoisotopic_mass": 37161.0
    },
    "refseq": {
        "ac": "XP_006235756",
        "name": "syntaxin-16 isoform X2",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006235756"
    },
    "gene_names": [
        {
            "name": "Stx16",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K528",
            "id": "A0A0G2K528"
        },
        {
            "name": "Stx16",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006235756",
            "id": "XP_006235756"
        }
    ],
    "protein_names": [
        {
            "name": "Syntaxin 16",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "A0A0G2K528"
        },
        {
            "name": "syntaxin-16 isoform X2",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006235756",
            "id": "XP_006235756"
        }
    ],
    "function": [],
    "disease": [
        {
            "disease_id": "DOID:0080222",
            "recommended_name": {
                "id": "DOID:0080222",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0080222",
                "name": "pseudohypoparathyroidism type IB",
                "description": "A pseudohypoparathyroidism characterized by isolated renal parathyroid hormone (PTH) resistance resulting in hypocalcemia, hyperphosphatemia and elevated PTH levels that has_material_basis_in mutations that alter the methylation pattern of GNAS on 20q13.32."
            },
            "synonyms": [
                {
                    "id": "MONDO:0011301",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011301",
                    "name": "pseudohypoparathyroidism type 1B",
                    "description": "Pseudohypoparathyroidism type 1B (PHP-1b) is a type of pseudohypoparathyroidism (PHP) characterized by localized resistance to parathyroid hormone (PTH) mainly in the renal tissues which manifests with hypocalcemia, hyperphosphatemia and elevated PTH levels. About 60-70% of patients also present with elevated TSH levels due to TSH resistance."
                },
                {
                    "id": "MONDO:0011301",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011301",
                    "name": "pseudohypoparathyroidism Ib",
                    "description": ""
                },
                {
                    "id": "MONDO:0011301",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011301",
                    "name": "PHP1B",
                    "description": ""
                },
                {
                    "id": "MONDO:0011301",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011301",
                    "name": "Php 1B",
                    "description": ""
                },
                {
                    "id": "MONDO:0011301",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011301",
                    "name": "pseudohypoparathyroidism type IB",
                    "description": ""
                },
                {
                    "id": "MONDO:0011301",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011301",
                    "name": "pseudohypoparathyroidism, type 1B",
                    "description": ""
                },
                {
                    "id": "MONDO:0011301",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011301",
                    "name": "pseudohypoparathyroidism, type IB",
                    "description": ""
                },
                {
                    "id": "MIM:603233",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/603233",
                    "name": "Pseudohypoparathyroidism 1B",
                    "description": "Pseudohypoparathyroidism 1B"
                }
            ],
            "evidence": [
                {
                    "id": "0080222",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080222"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A0G2K528",
                    "url": "https://www.uniprot.org/uniprot/A0A0G2K528"
                }
            ],
            "common_name": "Rat"
        }
    ],
    "gene": [
        {
            "name": "Stx16",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K528",
            "locus": {
                "chromosome": "3",
                "start_pos": 162882489,
                "end_pos": 162853782,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSRNOG00000005281",
                        "url": "https://www.ensembl.org/id/ENSRNOG00000005281"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSRNOG00000005281",
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000005281",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "cd15845",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15845",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "362283",
            "url": "https://www.ncbi.nlm.nih.gov/gene/362283",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR000727",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000727",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR006011",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR006011",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR006012",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR006012",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR010989",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR010989",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR045242",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR045242",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "rno:362283",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:362283",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "RKMCIIL",
            "url": "https://omabrowser.org/oma/group/RKMCIIL/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "2876074at2759",
            "url": "http://www.orthodb.org/?query=2876074at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR19957",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19957",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR19957:SF83",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19957:SF83",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00804",
            "url": "http://pfam.xfam.org/family/PF00804",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF05739",
            "url": "http://pfam.xfam.org/family/PF05739",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-RNO-6811438",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-6811438",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-RNO-6811440",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-6811440",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "XP_006235755",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006235755",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "1309423",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1309423",
            "database": "RGD",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "A0A0G2K528",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K528",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A0G2K528-1",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K528-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I5ZW54",
            "url": "https://www.uniprot.org/uniprot/A0A8I5ZW54",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I5ZW54-1",
            "url": "https://www.uniprot.org/uniprot/A0A8I5ZW54-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I6AQ84",
            "url": "https://www.uniprot.org/uniprot/A0A8I6AQ84",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I6AQ84-1",
            "url": "https://www.uniprot.org/uniprot/A0A8I6AQ84-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "D3Z9R7",
            "url": "https://www.uniprot.org/uniprot/D3Z9R7",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "D3Z9R7-1",
            "url": "https://www.uniprot.org/uniprot/D3Z9R7-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MATRRLTDAFLLLRNNSIQNRQLLAEQVSSHTTSSPLHSRSIAAELDELADDRMALVSGISLDPEAAIGVTKRSPPKWVDGVDEIQYDVGRIKQKMRELASLHDKHLNRPTLDDSSEEEHAIEITTQEVTQLFHRCQRAVQALPSRARRTCSEQEERLLRNVVASLAQALQELSTSFRHAQSDYLKRMKNREERSQHFFDTPVPLMDDGDDATLYGQGFTDDQLVLVEQNTLVVEEREREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCVKTEDGLKQLHKAEQYQKKNRKMLVILILVAVIVVLIVVLIAVKSR",
        "length": 326,
        "header": "tr|A0A0G2K528-1|A0A0G2K528_RAT Isoform 1 of Syntaxin 16  OS=Rattus norvegicus OX=10116 GN=Stx16 PE=1 SV=2 CANONICAL=A0A0G2K528-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A0G2K528-1",
            "url": "",
            "sequence": {
                "sequence": "MATRRLTDAFLLLRNNSIQNRQLLAEQVSSHTTSSPLHSRSIAAELDELADDRMALVSGISLDPEAAIGVTKRSPPKWVDGVDEIQYDVGRIKQKMRELASLHDKHLNRPTLDDSSEEEHAIEITTQEVTQLFHRCQRAVQALPSRARRTCSEQEERLLRNVVASLAQALQELSTSFRHAQSDYLKRMKNREERSQHFFDTPVPLMDDGDDATLYGQGFTDDQLVLVEQNTLVVEEREREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCVKTEDGLKQLHKAEQYQKKNRKMLVILILVAVIVVLIVVLIAVKSR",
                "length": 326,
                "header": "tr|A0A0G2K528-1|A0A0G2K528_RAT Isoform 1 of Syntaxin 16  OS=Rattus norvegicus OX=10116 GN=Stx16 PE=1 SV=2 CANONICAL=A0A0G2K528-1"
            },
            "locus": {
                "chromosome": "3",
                "start_pos": 162879874,
                "end_pos": 162854532,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000088286.2",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000088286.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000073268.2",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000073268.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A8I5ZW54-1",
            "url": "",
            "sequence": {
                "sequence": "MALCVCLPMPFFCSSCADGPTATPQPQELDELADDRMALVSGISLDPEAAIGVTKRSPPKWVDGVDEIQYDVGRIKQKMRELASLHDKHLNRPTLDDSSEEEHAIEITTQEVTQLFHRCQRAVQALPSRARRTCSEQEERLLRNVVASLAQALQELSTSFRHAQSDYLKRMKNREERSQHFFDTPVPLMDDGDDATLYGQGFTDDQLVLVEQNTLVVEEREREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCVKTEDGLKQLHKAEQYQKKNRKMLVILILVAVIVVLIVVLIAVKSR",
                "length": 309,
                "header": "tr|A0A8I5ZW54-1|A0A8I5ZW54_RAT Computationally mapped isoform of Syntaxin 16  OS=Rattus norvegicus OX=10116 GN=Stx16 PE=1 SV=1 CANONICAL=A0A0G2K528-1"
            },
            "locus": {
                "chromosome": "3",
                "start_pos": 162879874,
                "end_pos": 162864281,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000106302.1",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000106302.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000083230.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000083230.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A8I6AQ84-1",
            "url": "",
            "sequence": {
                "sequence": "MATRRLTDAFLLLRNNSIQNRQLLAEQLADDRMALVSGISLDPEAAIGVTKRSPPKWVDGVDEIQYDVGRIKQKMRELASLHDKHLNRPTLDDSSEEEHAIEITTQEVTQLFHRCQRAVQALPSRARRTCSEQEERLLRNVVASLAQALQELSTSFRHAQSDYLKRMKNREERSQHFFDTPVPLMDDGDDATLYGQGFTDDQLVLVEQNTLVVEEREREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCVKTEDGLKQLHKSCPPPCHRNPLILLVL",
                "length": 287,
                "header": "tr|A0A8I6AQ84-1|A0A0G2K528_RAT Computationally mapped isoform of Syntaxin 16  OS=Rattus norvegicus OX=10116 GN=Stx16 PE=1 SV=1 CANONICAL=A0A0G2K528-1"
            },
            "locus": {
                "chromosome": "3",
                "start_pos": 162878598,
                "end_pos": 162854532,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000095901.1",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000095901.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000096219.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000096219.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "D3Z9R7-1",
            "url": "",
            "sequence": {
                "sequence": "MATRRLTDAFLLLRNNSIQNRQLLAEQVSSHTTSSPLHSRSIAALADDRMALVSGISLDPEAAIGVTKRSPPKWVDGVDEIQYDVGRIKQKMRELASLHDKHLNRPTLDDSSEEEHAIEITTQEVTQLFHRCQRAVQALPSRARRTCSEQEERLLRNVVASLAQALQELSTSFRHAQSDYLKRMKNREERSQHFFDTPVPLMDDGDDATLYGQGFTDDQLVLVEQNTLVVEEREREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCVKTEDGLKQLHKAEQYQKKNRKMLVILILVAVIVVLIVVLIAVKSR",
                "length": 322,
                "header": "tr|D3Z9R7-1|A0A0G2K528_RAT Computationally mapped isoform of Syntaxin 16  OS=Rattus norvegicus OX=10116 GN=Stx16 PE=1 SV=2 CANONICAL=A0A0G2K528-1"
            },
            "locus": {
                "chromosome": "3",
                "start_pos": 162879874,
                "end_pos": 162854532,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000066279.2",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000066279.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000062099.2",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000062099.2"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [
        {
            "id": "rno:362283",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:362283",
            "resource": "KEGG Pathway"
        },
        {
            "id": "R-RNO-6811438",
            "name": "Intra-Golgi traffic",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-6811438",
            "resource": "Reactome",
            "description": "Intra-Golgi traffic"
        },
        {
            "id": "R-RNO-6811440",
            "name": "Retrograde transport at the Trans-Golgi-Network",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-6811440",
            "resource": "Reactome",
            "description": "Retrograde transport at the Trans-Golgi-Network"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "O14662-1",
            "protein_name": "Syntaxin-16",
            "gene_name": "STX16",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MATRRLTDAFLLLRNNSIQNRQLLAEQVSSHITSSPLHSRSIAAELDELADDRMALVSGISLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQSGYLKRMKNREERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNRKMLVILILFVIIIVLIVVLVGVKSR",
                "length": 325
            },
            "evidence": [
                {
                    "id": "45237727",
                    "url": "http://www.informatics.jax.org/homology/45237727",
                    "database": "MGI"
                }
            ],
            "common_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q8BVI5-1",
            "protein_name": "Syntaxin-16",
            "gene_name": "Stx16",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MATRRLTDAFLLLRNNSIQTRQLLAEQVSSHTTSSPLHSRSIAAELDELADDRMALVSGISLDPEAAIGVTKRSPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEVTQLFHRCQRAVQALPSRARRACSEQEERLLRNVVASLAQALQELSTSFRHAQSDYLKRMKNREERSQHFFDTPVPLMDDGDDATLYGQGFTDDQLVLVEQNTLMVEEREREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCVKTEDGLKQLHKAEQYQKKNRKMLVIVILVAVIIVLLVALVAVKSR",
                "length": 326
            },
            "evidence": [
                {
                    "id": "45237727",
                    "url": "http://www.informatics.jax.org/homology/45237727",
                    "database": "MGI"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Cellular Component",
                "total": 9,
                "go_terms": [
                    {
                        "name": "cytoplasm",
                        "id": "GO:0005737",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K528",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K528"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "Golgi apparatus",
                        "id": "GO:0005794",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K528",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K528"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cytosol",
                        "id": "GO:0005829",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K528",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K528"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "perinuclear region of cytoplasm",
                        "id": "GO:0048471",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K528",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K528"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "endomembrane system",
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