{ "uniprot_canonical_ac": "A0A0G2K3R9-1", "uniprot_ac": "A0A0G2K3R9", "uniprot_id": "A0A0G2K3R9_RAT", "mass": { "chemical_mass": 35076.0, "monoisotopic_mass": 35076.0 }, "refseq": { "ac": "NP_001000257", "name": "olfactory receptor Olr357", "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000257" }, "gene_names": [ { "name": "Or5b123b", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A0A0G2K3R9", "id": "A0A0G2K3R9" }, { "name": "Olr357; ratchr1-216468017-216468964_ORF", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000257", "id": "NP_001000257" }, { "name": "Or5b123b", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000257", "id": "NP_001000257" } ], "protein_names": [ { "name": "Olfactory receptor 357", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "A0A0G2K3R9" }, { "name": "olfactory receptor Olr357", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000257", "id": "NP_001000257" }, { "name": "olfactory receptor gene Olr357; olfactory receptor 357", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000257", "id": "NP_001000257" } ], "function": [ { "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_001000257", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000257" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K3R9", "url": "https://www.uniprot.org/uniprot/A0A0G2K3R9" } ], "common_name": "Rat" } ], "gene": [ { "name": "Or5b123b", "url": "https://www.uniprot.org/uniprot/A0A0G2K3R9", "locus": {} } ], "crossref": [ { "id": "cd15407", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15407", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "293794", "url": "https://www.ncbi.nlm.nih.gov/gene/293794", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "rno:293794", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:293794", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CHAAVCK", "url": "https://omabrowser.org/oma/group/CHAAVCK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "5401587at2759", "url": "http://www.orthodb.org/?query=5401587at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018:SF40", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018:SF40", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "http://pfam.xfam.org/family/PF13853", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "NP_001000257", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001000257", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "1333477", "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1333477", "database": "RGD", "categories": [ "Organism-specific" ] }, { "id": "A0A0G2K3R9", "url": "https://www.uniprot.org/uniprot/A0A0G2K3R9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0G2K3R9-1", "url": "https://www.uniprot.org/uniprot/A0A0G2K3R9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMQNNSELTEFILVGLTDVQFLQVPLFIIFTLIYLTTLVGNLGMILLIILDSRLHTPMYFFLSNLSFADCVYASAVTPKVIEGFLTEDKIISYNACAAQMFFFGVFAIIESFLLASMAYDCHAAVCKPLHYSTTMTTMICSLLLAGSYVSGILQSSIHVAFTFHLSFCHSNVVNHFFCDIPPLLSLSCSSIYTNEIVLFMLAAFDVGFTLLVILTSYLLIFVAILRMNSAESRKKAISTCSSHLTTVSIFYGTIIFMYLQPSSSHSMDTDKMASVFYTMVIPMLNPIVYSLRNKEVKNAFKKVARKALSSLGLVN", "length": 315, "header": "tr|A0A0G2K3R9-1|A0A0G2K3R9_RAT Isoform 1 of Olfactory receptor 357 OS=Rattus norvegicus OX=10116 GN=Or5b123b PE=4 SV=1 CANONICAL=A0A0G2K3R9-1" }, "isoforms": [ { "isoform_ac": "A0A0G2K3R9-1", "url": "", "sequence": { "sequence": "MMQNNSELTEFILVGLTDVQFLQVPLFIIFTLIYLTTLVGNLGMILLIILDSRLHTPMYFFLSNLSFADCVYASAVTPKVIEGFLTEDKIISYNACAAQMFFFGVFAIIESFLLASMAYDCHAAVCKPLHYSTTMTTMICSLLLAGSYVSGILQSSIHVAFTFHLSFCHSNVVNHFFCDIPPLLSLSCSSIYTNEIVLFMLAAFDVGFTLLVILTSYLLIFVAILRMNSAESRKKAISTCSSHLTTVSIFYGTIIFMYLQPSSSHSMDTDKMASVFYTMVIPMLNPIVYSLRNKEVKNAFKKVARKALSSLGLVN", "length": 315, "header": "tr|A0A0G2K3R9-1|A0A0G2K3R9_RAT Isoform 1 of Olfactory receptor 357 OS=Rattus norvegicus OX=10116 GN=Or5b123b PE=4 SV=1 CANONICAL=A0A0G2K3R9-1" }, "locus": { "chromosome": "1", "start_pos": 210344600, "end_pos": 210343656, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000073539.3", "url": "https://www.ensembl.org/id/ENSRNOT00000073539.3" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000072749.1", "url": "https://www.ensembl.org/id/ENSRNOP00000072749.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "rno:293794", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:293794", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A140LIR8-1", "protein_name": "Olfactory receptor", "gene_name": "Or5b121", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKYLTAFLFTPIFLFLGQQCKQKRLKIISKRFLFLRASTFRQKYYELPFRRHQEKLSKHWKDAPLLQTPLFIIFTLTYLTTLFGNLGMILLILLDSRLHTPMYFFLSNLSLVDCVYASAVTPKVMEGFLIENKIISYNACAAQMFFFVAFVITESFILASMAYDRYAAVCKPLHYSTTMTTMICVLLLAGSYVSGLLQSSIHVSFTFQLSFCHSNVVNHFFCDIPPLLALSCSSIYTNEIILFMLAAFNVAFTLLVILSSYLLIFVAILKMRSAESRKKTISTCASHLTTVSIFYGTIIFMYLQPSSNHSMDTDKLASVFYTMVIPMLNPLVYSLRNKEVKNAFKKVAGKAVLSLGLVN", "length": 359 }, "evidence": [ { "id": "45245399", "url": "http://www.informatics.jax.org/homology/45245399", "database": "MGI" } ], "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A8I5ZNA2-1", "protein_name": "Olfactory receptor", "gene_name": "Or5b116", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTLMENISEVTEFILVGLTDAPELQIPLFIIFTLIYLITLFGNLGMIMLILLDSRLHTPMYFFLCNLSLVDCVYASAITPKVMEAFFTGNNTISFNGCAAQMFFFVAFIAIESLILASMAYDRHAAVCKPLHYTTIMTSTTCIVIATCCYMCGILQSSIHVALAFRLSFCHSNMINHFFCDIPPLLTISCSDTHTNEITLLILATLDVVFTLLVILNTYLLIFIAILRMRSAEAQRKAFSTCASHLITVSIFFGSLTFMYLQPSSSHSMDTDKIASVFYTMVIPMLNPLVYSLRNKEVKNAFKKVVGKLMSSFS", "length": 314 }, "evidence": [ { "id": "45245396", "url": "http://www.informatics.jax.org/homology/45245396", "database": "MGI" }, { "id": "45245399", "url": "http://www.informatics.jax.org/homology/45245399", "database": "MGI" }, { "id": "45245398", "url": "http://www.informatics.jax.org/homology/45245398", "database": "MGI" }, { "id": "45245397", "url": "http://www.informatics.jax.org/homology/45245397", "database": "MGI" } ], "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TQQ7-1", "protein_name": "Olfactory receptor", "gene_name": "Or5b120", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMQNISELSEFILVGLTDAPFLQTPLFIIFTLIYLTTLFGNLGMIMLILLDSRLHTPMYFFLSNLSLVDCVYASAVTPKVMEGFLTGNKIISYNACAAQMFFFVAFAITENFILASMAYDRHAAVCKPLHYSTTMTTTICVLLLVGSYLSGLLHSSIHVSFTFHLSFCRSNVVNHFFCDIPPLLAVSCSSIRTNEIILFMLAGFDVAFSLLVILTSYLLISVAIVRMRSAESRKKAISTCASHLTTVSIFYGTIIFMYLQPSSNHSMDTDKMASVFYTMVIPMLNPLVYSLRNKEVKNAFKKVAGKAVLSLGLIN", "length": 315 }, "evidence": [ { "id": "45245396", "url": "http://www.informatics.jax.org/homology/45245396", "database": "MGI" } ], "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VEU6-1", "protein_name": "Olfactory receptor", "gene_name": "Or5b122", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMQNISELSEFILLGLTDAPFLQTPLFIIFTLIYLTTLFGNLGMILLILLDSRLHTPMYFFLSNLSLVDCVYASAVTPKVIEGFLTENKIISYNACAAQMFFFVAFAITECFILASMAYDRHAAVCKPLHYSTTMTTTICVLLLAGSYLSGLLQSSIHVSFTFHLSFCRSNVVNHFFCDIPPLLALSCSSIHINEIILFMLAGFNVVFSLLVILTSYLLISVAIVRMRSAESRKKAISTCASHLTTVSIFYGTIIFMYLQPSSNHSMDTDKMASVFYTMVIPMLNPLVYSLRNKEVKNAVRKVAGKALFSLGLVN", "length": 315 }, "evidence": [ { "id": "45245397", "url": "http://www.informatics.jax.org/homology/45245397", "database": "MGI" } ], "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VFQ6-1", "protein_name": "Olfactory receptor", "gene_name": "Or5b123", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIQNISELSEFILVGLTDAPFLQIPLFIIFTLIYLTTLFGNLGMILLILLDSRLHTPMYFFLSNLSLVDCVYASAVTPKVMEGFLTGNKIISYNACAAQMFFFAAFATVESFMLASMAYDRHAAVCKPLHYSTTMTTTICVLLLAGSYVSGLLQSSIHVSFTFQLSFCHSNVVNHFFCDIPPLLALSCSSIHTNEIILFMLAAFNVAFTLLVILSSYLLIFVAILRMRSAESRKKAISTCASHLTTVSIFYGTIIFMYLQPSSNHSMDTDKMASVFYTMVIPMLNPLVYSLRNKEVKNAFKKVAGKAVLSLGLVN", "length": 315 }, "evidence": [ { "id": "45245398", "url": "http://www.informatics.jax.org/homology/45245398", "database": "MGI" } ], "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K3R9", "url": "https://www.uniprot.org/uniprot/A0A0G2K3R9" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K3R9", "url": "https://www.uniprot.org/uniprot/A0A0G2K3R9" } ], "pmid": "" }, { "name": "odorant binding", "id": "GO:0005549", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005549", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K3R9", "url": "https://www.uniprot.org/uniprot/A0A0G2K3R9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K3R9", "url": "https://www.uniprot.org/uniprot/A0A0G2K3R9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K3R9", "url": "https://www.uniprot.org/uniprot/A0A0G2K3R9" } ], "pmid": "" }, { "name": "sensory perception of smell", "id": "GO:0007608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007608", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K3R9", "url": "https://www.uniprot.org/uniprot/A0A0G2K3R9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 4, "end_pos": 6, "annotation": "n_glycosylation_sequon" }, { "start_pos": 64, "end_pos": 66, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "synthesized_glycans": [], "cluster_types": [ { "name": "homologset.mgi", "label": "MGI Homologs" } ], "section_stats": [ { "table_id": "glycosylation", 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