{
    "uniprot_canonical_ac": "A0A0G2K309-1",
    "uniprot_ac": "A0A0G2K309",
    "uniprot_id": "ORNT1_RAT",
    "mass": {
        "chemical_mass": 32797.0,
        "monoisotopic_mass": 32797.0
    },
    "refseq": {
        "ac": "NP_001041345",
        "name": "mitochondrial ornithine transporter 1",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001041345"
    },
    "gene_names": [
        {
            "name": "Slc25a15",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K309",
            "id": "A0A0G2K309"
        },
        {
            "name": "Ab1-114; Ornt1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006253412",
            "id": "XP_006253412"
        },
        {
            "name": "Slc25a15",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006253412",
            "id": "XP_006253412"
        }
    ],
    "protein_names": [
        {
            "name": "Mitochondrial ornithine transporter 1",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "A0A0G2K309"
        },
        {
            "name": "Solute carrier family 25 member 15",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "A0A0G2K309"
        },
        {
            "name": "mitochondrial ornithine transporter 1 isoform X1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006253412",
            "id": "XP_006253412"
        },
        {
            "name": "mitochondrial ornithine transporter 1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001041345",
            "id": "NP_001041345"
        },
        {
            "name": "ornithine transporter) member 15; solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001041345",
            "id": "NP_001041345"
        }
    ],
    "function": [
        {
            "annotation": "Mitochondrial ornithine-citrulline antiporter. Catalyzes the exchange between cytosolic ornithine and mitochondrial citrulline plus an H(+), the proton compensates the positive charge of ornithine thus leading to an electroneutral transport. Plays a crucial role in the urea cycle, by connecting the cytosolic and the intramitochondrial reactions of the urea cycle (PubMed:9359400, PubMed:10417335). Lysine and arginine are also transported by the antiport mechanism (By similarity). In addition, catalyzes an electroneutral exchange of ornithine or lysine for H(+), a reaction driven by the pH gradient across the inner membrane (PubMed:10417335).",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A0G2K309",
                    "url": "https://www.uniprot.org/uniprot/A0A0G2K309#function"
                },
                {
                    "database": "PubMed",
                    "id": "10417335",
                    "url": "https://glygen.org/publication/PubMed/10417335"
                },
                {
                    "database": "PubMed",
                    "id": "9359400",
                    "url": "https://glygen.org/publication/PubMed/9359400"
                },
                {
                    "database": "UniProtKB",
                    "id": "Q9Y619",
                    "url": "https://www.uniprot.org/uniprot/Q9Y619#function"
                }
            ]
        },
        {
            "annotation": "Transcriptional Activation of ORNT1 mRNA by dexamethasone in hepatocytes.",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001041345",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001041345"
                },
                {
                    "database": "PubMed",
                    "id": "12061769",
                    "url": "https://glygen.org/publication/PubMed/12061769"
                }
            ]
        }
    ],
    "disease": [
        {
            "disease_id": "DOID:0050720",
            "recommended_name": {
                "id": "DOID:0050720",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0050720",
                "name": "ornithine translocase deficiency",
                "description": "An amino acid metabolic disorder that has_material_basis_in deficiency of ornithine translocase resulting in the accumulation of ammonia in the blood."
            },
            "synonyms": [
                {
                    "id": "DOID:0050720",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0050720",
                    "name": "Hyperornithinemia-Hyperammonemia-Homocitrullinuria (HHH) syndrome",
                    "description": ""
                },
                {
                    "id": "DOID:0050720",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0050720",
                    "name": "HHH syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0009393",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009393",
                    "name": "ornithine translocase deficiency",
                    "description": "A rare, genetic disorder of urea cycle metabolism characterized by either a neonatal-onset with manifestations of lethargy, poor feeding, vomiting and tachypnea or, more commonly, presentations in infancy, childhood or adulthood with chronic neurocognitive deficits, acute encephalopathy and/or coagulation defects or other chronic liver dysfunction."
                },
                {
                    "id": "MONDO:0009393",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009393",
                    "name": "HHH syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0009393",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009393",
                    "name": "ORNT1 deficiency",
                    "description": ""
                },
                {
                    "id": "MONDO:0009393",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009393",
                    "name": "hyperornithinemia-hyperammonemia-homocitrullinemia syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0009393",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009393",
                    "name": "hyperornithinemia-hyperammonemia-homocitrullinuria (HHH) syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0009393",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009393",
                    "name": "ornithine carrier deficiency",
                    "description": ""
                },
                {
                    "id": "MONDO:0009393",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009393",
                    "name": "ornithine translocase deficiency",
                    "description": ""
                },
                {
                    "id": "MONDO:0009393",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009393",
                    "name": "triple H syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0009393",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009393",
                    "name": "HHH",
                    "description": ""
                },
                {
                    "id": "MONDO:0009393",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009393",
                    "name": "HHHS",
                    "description": ""
                },
                {
                    "id": "MONDO:0009393",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009393",
                    "name": "Hhh syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0009393",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009393",
                    "name": "hyperornithinemia-hyperammonemia-homocitrullinuria syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0009393",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009393",
                    "name": "ornithine translocase deficiency syndrome",
                    "description": ""
                },
                {
                    "id": "MIM:238970",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/238970",
                    "name": "Hyperornithinemia-hyperammonemia-homocitrullinuria syndrome",
                    "description": "Hyperornithinemia-hyperammonemia-homocitrullinuria syndrome"
                }
            ],
            "evidence": [
                {
                    "id": "0050720",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050720"
                }
            ]
        },
        {
            "disease_id": "DOID:9252",
            "recommended_name": {
                "id": "DOID:9252",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:9252",
                "name": "amino acid metabolic disorder",
                "description": "An inherited metabolic disorder that is characterized by impaired synthesis and degradation of amino acids."
            },
            "synonyms": [
                {
                    "id": "DOID:9252",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:9252",
                    "name": "inborn errors of amino acid metabolism",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "9252",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:9252"
                }
            ]
        },
        {
            "disease_id": "DOID:9273",
            "recommended_name": {
                "id": "DOID:9273",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:9273",
                "name": "citrullinemia",
                "description": "An inherited urea cycle disorder that involves the accumulation of ammonia and other toxic substances in the blood."
            },
            "synonyms": [
                {
                    "id": "DOID:9273",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:9273",
                    "name": "ASS deficiency",
                    "description": ""
                },
                {
                    "id": "DOID:9273",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:9273",
                    "name": "deficiency of citrulline-aspartate ligase",
                    "description": ""
                },
                {
                    "id": "DOID:9273",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:9273",
                    "name": "classic citrullinemia",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "9273",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:9273"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A0G2K309",
                    "url": "https://www.uniprot.org/uniprot/A0A0G2K309"
                }
            ],
            "common_name": "Rat"
        }
    ],
    "gene": [
        {
            "name": "Slc25a15",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K309",
            "locus": {
                "chromosome": "16",
                "start_pos": 69653010,
                "end_pos": 69634414,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSRNOG00000011881",
                        "url": "https://www.ensembl.org/id/ENSRNOG00000011881"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSRNOG00000011881",
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000011881",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "306574",
            "url": "https://www.ncbi.nlm.nih.gov/gene/306574",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR018108",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR018108",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR023395",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR023395",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "rno:306574",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:306574",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "PIDCFRQ",
            "url": "https://omabrowser.org/oma/group/PIDCFRQ/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "4064096at2759",
            "url": "http://www.orthodb.org/?query=4064096at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR45624",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45624",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR45624:SF22",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45624:SF22",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00153",
            "url": "http://pfam.xfam.org/family/PF00153",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_A0A0G2K309",
            "url": "http://purl.obolibrary.org/obo/PR_A0A0G2K309",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "R-RNO-70635",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-70635",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "XP_006253412",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006253412",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "1311488",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1311488",
            "database": "RGD",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "34991",
            "url": "https://www.rhea-db.org/rhea/34991",
            "database": "Rhea",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "70787",
            "url": "https://www.rhea-db.org/rhea/70787",
            "database": "Rhea",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "70791",
            "url": "https://www.rhea-db.org/rhea/70791",
            "database": "Rhea",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "70795",
            "url": "https://www.rhea-db.org/rhea/70795",
            "database": "Rhea",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "70799",
            "url": "https://www.rhea-db.org/rhea/70799",
            "database": "Rhea",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "A0A0G2K309",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K309",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A0G2K309-1",
            "url": "https://www.uniprot.org/uniprot/A0A0G2K309-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I6A3Y8",
            "url": "https://www.uniprot.org/uniprot/A0A8I6A3Y8",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I6A3Y8-1",
            "url": "https://www.uniprot.org/uniprot/A0A8I6A3Y8-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q7TPA1",
            "url": "https://www.uniprot.org/uniprot/Q7TPA1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q7TPA1-1",
            "url": "https://www.uniprot.org/uniprot/Q7TPA1-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MKSNPAIQAAIDLTAGAAGGTACVLTGQPFDTMKVKMQTFPDLYRGLTDCCLRTYSQVGFRGFYKGTSPALIANIAENSVLFMCYGFCQQVVRKVVGLDRQAKLSDLQNAAAGSFASAFAALVLCPTELVKCRLQTMYEMETSGKIAASQNTVWSVVKEIFRKDGPLGFYHGLSSTLLREVPGYFFFFGGYELSRSFFASGRSKDELGPIPLMLSGGFGGICLWLAVYPVDCIKSRIQVLSMTGKQTGLIRTFLSIVKNEGITALYSGLKPTMIRAFPANGALFLAYEYSRKLMMSQLEAC",
        "length": 301,
        "header": "sp|A0A0G2K309-1|ORNT1_RAT Isoform 1 of Mitochondrial ornithine transporter 1  OS=Rattus norvegicus OX=10116 GN=Slc25a15 PE=1 SV=1 CANONICAL=A0A0G2K309-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A0G2K309-1",
            "url": "",
            "sequence": {
                "sequence": "MKSNPAIQAAIDLTAGAAGGTACVLTGQPFDTMKVKMQTFPDLYRGLTDCCLRTYSQVGFRGFYKGTSPALIANIAENSVLFMCYGFCQQVVRKVVGLDRQAKLSDLQNAAAGSFASAFAALVLCPTELVKCRLQTMYEMETSGKIAASQNTVWSVVKEIFRKDGPLGFYHGLSSTLLREVPGYFFFFGGYELSRSFFASGRSKDELGPIPLMLSGGFGGICLWLAVYPVDCIKSRIQVLSMTGKQTGLIRTFLSIVKNEGITALYSGLKPTMIRAFPANGALFLAYEYSRKLMMSQLEAC",
                "length": 301,
                "header": "sp|A0A0G2K309-1|ORNT1_RAT Isoform 1 of Mitochondrial ornithine transporter 1  OS=Rattus norvegicus OX=10116 GN=Slc25a15 PE=1 SV=1 CANONICAL=A0A0G2K309-1"
            },
            "locus": {
                "chromosome": "16",
                "start_pos": 69652472,
                "end_pos": 69634474,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000050637",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000050637"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000045952",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000045952"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A8I6A3Y8-1",
            "url": "",
            "sequence": {
                "sequence": "PGSSPFLSATTQLHYGGTACVLTGQPFDTMKVKMQTFPDLYRGLTDCCLRTYSQVGFRGFYKGTSPALIANIAENSVLFMCYGFCQQVVRKVVGLDRQAKLSDLQNAAAGSFASAFAALVLCPTELVKCRLQTMYEMETSGKIAASQNTVWSVVKEIFRKDGPLGFYHGLSSTLLREVPGYFFFFGGYELSRSFFASGRSKDELGPIPLMLSGGFGGICLWLAVYPVDCIKSRIQVLSMTGKQTGLIRTFLSIVKNEGGYRLSESRLYDVSFVQPKTCLSGVHYVGILKLGLREGITALYSGLKPTMIRAFPANGALFLAYEYSRKLMMSQLEAC",
                "length": 335,
                "header": "tr|A0A8I6A3Y8-1|A0A8I6A3Y8_RAT Computationally mapped isoform of Solute carrier family 25 member 15  OS=Rattus norvegicus OX=10116 GN=Slc25a15 PE=1 SV=1 CANONICAL=A0A0G2K309-1"
            },
            "locus": {
                "chromosome": "16",
                "start_pos": 69652472,
                "end_pos": 69639188,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000097321.1",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000097321.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000087225.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000087225.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q7TPA1-1",
            "url": "",
            "sequence": {
                "sequence": "MKSNPAIQAAIDLTAGAAGGTACVLTGQPFDTMKVKMQTFPDLYRGLTDCCLRTYSQVGFRGFYKGTSPALIANIAENSVLFMCYGFCQQVVRKVVGLDRQAKLSDLQNAAAGSFASAFAALVLCPTELVKCRLQTMYEMETSGKIAASQNTVWSVVKEIFRKDGPLGFYHGLSSTLLREVPGYFFFFGGYELSRSFFASGRSKDELGPIPLMLSGGFGGICLWLAVYPVDCIKSRIQVLSMTGKQTGLIRTFLSIVKNEGGYRLSESRLYDVSFVQPKTCLSGVHYVGILKLGLREGITALYSGLKPTMIRAFPANGALFLAYEYSRKLMMSQLEAC",
                "length": 338,
                "header": "tr|Q7TPA1-1|Q7TPA1_RAT Computationally mapped isoform of Mitochondrial ornithine transporter 1  OS=Rattus norvegicus OX=10116 GN=Slc25a15 PE=1 SV=1 CANONICAL=A0A0G2K309-1"
            },
            "locus": {
                "chromosome": "16",
                "start_pos": 69652472,
                "end_pos": 69634474,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000050637",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000050637"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000045952",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000045952"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [
        {
            "title": "The purified and reconstituted ornithine/citrulline carrier from rat liver mitochondria catalyses a second transport mode: ornithine+/H+ exchange.",
            "journal": "The Biochemical journal",
            "date": "1999-08-01",
            "authors": "Indiveri C, Tonazzi A, Stipani I, Palmieri F",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A0G2K309",
                    "url": "https://www.uniprot.org/uniprot/A0A0G2K309"
                }
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            "reference": [
                {
                    "type": "PubMed",
                    "id": "10417335",
                    "url": "https://glygen.org/publication/PubMed/10417335"
                }
            ]
        },
        {
            "title": "Hormonal induction of hepatic mitochondrial ornithine/citrulline transporter mRNA.",
            "journal": "Biochemical and biophysical research communications",
            "date": "2002",
            "authors": "Morris SM Jr, Kepka-Lenhart D",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001041345",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001041345"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "12061769",
                    "url": "https://glygen.org/publication/PubMed/12061769"
                }
            ]
        },
        {
            "title": "The purified and reconstituted ornithine/citrulline carrier from rat liver mitochondria: electrical nature and coupling of the exchange reaction with H+ translocation.",
            "journal": "The Biochemical journal",
            "date": "1997-10-15",
            "authors": "Indiveri C, Tonazzi A, Stipani I, Palmieri F",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A0G2K309",
                    "url": "https://www.uniprot.org/uniprot/A0A0G2K309"
                }
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                {
                    "type": "PubMed",
                    "id": "9359400",
                    "url": "https://glygen.org/publication/PubMed/9359400"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "rno:306574",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:306574",
            "resource": "KEGG Pathway"
        },
        {
            "id": "R-RNO-70635",
            "name": "Urea cycle",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-70635",
            "resource": "Reactome",
            "description": "Urea cycle"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q9WVD5-1",
            "protein_name": "Mitochondrial ornithine transporter 1",
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                "length": 301
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        },
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            "common_name": "Human"
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                "name": "Molecular Function",
                "total": 4,
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                    {
                        "name": "L-ornithine transmembrane transporter activity",
                        "id": "GO:0000064",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000064",
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                            }
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                            }
                        ],
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                                "id": "A0A0G2K309",
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                            }
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                        "name": "L-arginine transmembrane transporter activity",
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                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061459",
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                                "id": "A0A0G2K309",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K309"
                            }
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                        "pmid": ""
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                ]
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                "name": "Cellular Component",
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                        "name": "mitochondrion",
                        "id": "GO:0005739",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739",
                        "evidence": [
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                                "id": "A0A0G2K309",
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                        "evidence": [
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                                "id": "A0A0G2K309",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K309"
                            }
                        ],
                        "pmid": ""
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                    {
                        "name": "membrane",
                        "id": "GO:0016020",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K309",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K309"
                            }
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                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 3,
                "go_terms": [
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                        "name": "L-lysine transmembrane transport",
                        "id": "GO:1903401",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903401",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K309",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K309"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "mitochondrial L-ornithine transmembrane transport",
                        "id": "GO:1990575",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990575",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K309",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K309"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "L-arginine transmembrane transport",
                        "id": "GO:1903826",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903826",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2K309",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K309"
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            "id": "34991",
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            "equation": "L-arginine(out) + L-ornithine(in) = L-arginine(in) + L-ornithine(out)",
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        {
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            "summary": "",
            "cellular_location": "",
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            "cellular_location": "",
            "input_participant_list": [],
            "output_participant_list": [],
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    "reaction_enzymes": [],
    "biomarkers": [],
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        {
            "name": "isoformset.uniprotkb",
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            "name": "homologset.mgi",
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