{ "uniprot_canonical_ac": "A0A0G2K1F7-1", "uniprot_ac": "A0A0G2K1F7", "uniprot_id": "A0A0G2K1F7_RAT", "mass": { "chemical_mass": 395569.0, "monoisotopic_mass": 395569.0 }, "refseq": {}, "gene_names": [ { "name": "Myo15a", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A0A0G2K1F7", "id": "A0A0G2K1F7" } ], "protein_names": [ { "name": "Myosin XVA", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "A0A0G2K1F7" } ], "function": [], "disease": [ { "disease_id": "DOID:0110488", "recommended_name": { "id": "DOID:0110488", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0110488", "name": "autosomal recessive nonsyndromic deafness 3", "description": "An autosomal recessive nonsyndromic deafness that is characterized by prelingual onset with severe to profound, stable hearing loss and has_material_basis_in mutation in the MYO15A gene on chromosome 17p11." }, "synonyms": [ { "id": "DOID:0110488", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0110488", "name": "DFNB3", "description": "" }, { "id": "DOID:0110488", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0110488", "name": "NRSD3", "description": "" }, { "id": "DOID:0110488", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0110488", "name": "autosomal recessive deafness 3, neurosensory nonsyndromic recessive deafness 3", "description": "" }, { "id": "MONDO:0010860", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010860", "name": "autosomal recessive nonsyndromic hearing loss 3", "description": "Any autosomal recessive nonsyndromic deafness in which the cause of the disease is a mutation in the MYO15A gene." }, { "id": "MONDO:0010860", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010860", "name": "DFNB3", "description": "" }, { "id": "MONDO:0010860", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010860", "name": "MYO15A autosomal recessive nonsyndromic deafness", "description": "" }, { "id": "MONDO:0010860", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010860", "name": "NRSD3", "description": "" }, { "id": "MONDO:0010860", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010860", "name": "autosomal recessive deafness 3, neurosensory nonsyndromic recessive deafness 3", "description": "" }, { "id": "MONDO:0010860", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010860", "name": "autosomal recessive nonsyndromic deafness 3", "description": "" }, { "id": "MONDO:0010860", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010860", "name": "autosomal recessive nonsyndromic deafness caused by mutation in MYO15A", "description": "" }, { "id": "MONDO:0010860", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010860", "name": "autosomal recessive nonsyndromic deafness type 3", "description": "" }, { "id": "MONDO:0010860", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010860", "name": "deafness, autosomal recessive 3", "description": "" }, { "id": "MONDO:0010860", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010860", "name": "deafness, autosomal recessive type 3", "description": "" }, { "id": "MONDO:0010860", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010860", "name": "neurosensory nonsyndromic recessive deafness 3", "description": "" }, { "id": "MIM:600316", "resource": "MIM", "url": "https://www.omim.org/entry/600316", "name": "Deafness, autosomal recessive, 3", "description": "Deafness, autosomal recessive, 3" } ], "evidence": [ { "id": "0110488", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:0110488" } ] }, { "disease_id": "DOID:10003", "recommended_name": { "id": "DOID:10003", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10003", "name": "sensorineural hearing loss", "description": "An inner ear disease that is characterized by hearing loss resulting from damage to the cochlea, auditory nerve and/or brainstem." }, "synonyms": [ { "id": "DOID:10003", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10003", "name": "High Frequency Hearing Loss", "description": "" }, { "id": "DOID:10003", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10003", "name": "High frequency deafness", "description": "" }, { "id": "DOID:10003", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10003", "name": "Perceptive deafness", "description": "" }, { "id": "DOID:10003", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10003", "name": "Perceptive hearing loss", "description": "" }, { "id": "DOID:10003", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10003", "name": "Perceptive hearing loss or deafness", "description": "" }, { "id": "DOID:10003", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10003", "name": "Sensorineural Deafness", "description": "" }, { "id": "DOID:10003", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10003", "name": "Sensory hearing loss", "description": "" }, { "id": "DOID:10003", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10003", "name": "central hearing loss", "description": "" }, { "id": "DOID:10003", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:10003", "name": "high-frequency hearing loss", "description": "" } ], "evidence": [ { "id": "10003", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:10003" } ] }, { "disease_id": "DOID:1432", "recommended_name": { "id": "DOID:1432", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1432", "name": "blindness", "description": "An eye disease characterized by a lack or loss of vision." }, "synonyms": [ { "id": "DOID:1432", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1432", "name": "vision impairment", "description": "" }, { "id": "DOID:1432", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1432", "name": "vision loss", "description": "" }, { "id": "DOID:1432", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:1432", "name": "visual impairment", "description": "" } ], "evidence": [ { "id": "1432", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:1432" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K1F7", "url": "https://www.uniprot.org/uniprot/A0A0G2K1F7" } ], "common_name": "Rat" } ], "gene": [ { "name": "Myo15a", "url": "https://www.uniprot.org/uniprot/A0A0G2K1F7", "locus": { "chromosome": "10", "start_pos": 45335340, "end_pos": 45278737, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSRNOG00000059219", "url": "https://www.ensembl.org/id/ENSRNOG00000059219" } ] } } ], "crossref": [ { "id": "cd01387", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01387", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13201", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13201", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14473", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14473", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "501699", "url": "https://www.ncbi.nlm.nih.gov/gene/501699", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000299", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000299", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000857", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000857", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001609", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001609", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019748", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019748", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035963", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035963", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041795", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041795", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "rno:501699", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:501699", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AIQSMIT", "url": "https://omabrowser.org/oma/group/AIQSMIT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR22692", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22692", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22692:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22692:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00063", "url": "http://pfam.xfam.org/family/PF00063", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF00373", "url": "http://pfam.xfam.org/family/PF00373", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF00612", "url": "http://pfam.xfam.org/family/PF00612", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF00784", "url": "http://pfam.xfam.org/family/PF00784", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF07653", "url": "http://pfam.xfam.org/family/PF07653", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "XP_001077498", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001077498", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "1561873", "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1561873", "database": "RGD", "categories": [ "Organism-specific" ] }, { "id": "A0A0G2JTE7", "url": "https://www.uniprot.org/uniprot/A0A0G2JTE7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0G2JTE7-1", "url": "https://www.uniprot.org/uniprot/A0A0G2JTE7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0G2K1F7", "url": "https://www.uniprot.org/uniprot/A0A0G2K1F7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0G2K1F7-1", "url": "https://www.uniprot.org/uniprot/A0A0G2K1F7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAKEEDEEKKAKKGKKGKKAPEPEKPKRSLKGTSRLFMGFRDRTPKISKKGQFRSASAFFWGLHTGPQKTKRKKKARTVLKSTSKLMTQMRVGKKKRAMKGKKPSFMVIRFPGRRGYGRLRPRAQSLSKASTAINWLTKKFLLKKAEESGSEQATLDAWLQRSSSRVGSRKLPFPSGAEILRHGGRLRRFPRSHSIYSSGEPVGFLPFEDEAPFRHAGSRKSLYGLEGFQDLGEYYDYHREGDDYYDQQSLYHYEEQEPYLAGFGGYSPAWPPYDDYGYPSGDPYNYYHPDYYGDTLYPAYGYGYGYGYDDLEPPYAPPSGYSSPYSYHDSFEDEAYPYSYYLDPYATHHMPYPPYDFPHDTPYDIPYFDPYGVPYAEGIYGGGAEAIYPPGVPYVYPEEPAFMYPWVPPPIMSPHNPYAHPMDDIAELEEPEEIGRERQSTSFRLPSAAFFEQQGMDKPARSKLSLIRKFRLFPRPQVKLFGKEKLEVPLPPSLDIPLPLGDAEGEEEEEEMPPVPTMPYTHPYWSFLTPRQRNLQRALSAFGARQGLGFGPEFGPPTPRPATSLARFLKKTLSEKKPIPRLRGSQKARGGRPPVREAAYKRFGYKLAGMDPDRPNTPIVLRRSQPQARNNNNSHGPPSPRPAPRTLTHWSALISPPMPGPSPSPASPLTPPFSPPLSRPPRLASPYSSPYGSLRQHPPPWAAPAHVPFPLQANWWGFAEPPGTSPEVAPDLMAFPVPRPSFRASRSRGAAYGFPRPSLIGSRRRPHLPSPQPSLRSLPGQGYHSPLGHLSPQLSLRRGPFQPPFPPPPRRPQSLRETFSLHRTSGRLGPPRSPVLGSPRPPSPPPLLKHPRHRSLNLPSRLPRTWRRLSEPPTRAVKPWIHRAYHPPPSAGPWGATAGSLEHQENQREPEDSETPWTVPPLAPSWDVDMATTQRPPSPWPEGVGSLRGFSRPPPVPENPLLEHTSPSCEPRPEDQASNLTGIFLGQHHDPGPGQLTKSANPSLENPEEVVISEDPQPSAEPETLNTPPNKTVVSERKALRPSASYPLVTCKQSRATWPQWHRWKTVSRTPAPLAPTRAPGSLLKAGKQLRDKPGRFAVVMPQVRGLSSFQQKGSAPLQPPEHSDQDPEHGPATQACSLRWPRLWSPADTHSPWPRIHTLSSPSPLRGHGGDCQSPKDLWKKTGSRSWQNKMHSIRNLPSVRSREQHREDGVEDMTQLEDLQETTVLTNLKTRFERNLIYTYIGSILVSVNPYRMFAIYGPEQVQQYSGRALGENPPHLFAIANLAFAKMLDAKQNQCVIISGESGSGKTEATKLLLRCLAAMNQRRDVMQQIKILEATPLLEAFGNAKTVRNDNSSRFGKFVEIFLEGGVICGAITSQYLLEKSRIVFQAKNERNYHIFYELLAGLPAQLRQAFSLQEAETYYYLNQGGNCEIAGKSDADDFRRLLAAMEVLGFTSEDQDSIFRILASILHLGNVYFEKHETDAQEVASVVSAREIQAVAELLQVSPEGLQKAITFKVTETIREKIFTPLTVESAVDARDAIAKVLYALLFGWLITRVNALVSPKQDTLSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQEEYIREQMDWREIAFADNQPCINLISLKPYGILRILDDQCCFPQATDHTFLQKCHYHHGANPLYCKPKMPLPEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVHSRTRVVAHLFSSHAAQTAPPRLGKSSSITRLYKAHTVAAKFQQSLLDLVEKMERCNPLFVRCLKPNHKKEPGLFEPDVMMAQLRYSGVLETVRIRKEGFPVRLPFQVFIDRYRCLVALKLNVPADGDMCVSLLSRLCTVTPDMYRVGVSKLFLKEHLHQLLESMRERVLNRAALTLQRYLRGFFTQRRFRSLRQKIILLQSRARGFLARQRYQQMRQSLLKFRSLVHTYVNRRRYLKLRAERRRRAQEAWLREQEELSKREVVPVRHLEVPAEVAGLLQAAAGLKPSSVPQVAIVRAPRLQAEPCVTLPLDINNYPMAKFIRCHFKEPSFGMLTVPLKMPLTQMLVEHHAEAISVFKLILRFMGDPHLHGTQEMILGNYIVHQGLVEPALRDEILAQLANQVWRNPNAYNAKRGWLLLAACLSGFAPSSHLDKFLLKFVSDYGQNGFQAVCQHRLLQAMGSGAARTFPPTQLEWTAIQEKASMALDVSCFNGDQFSCPVHPWSTGEAVAGDILKHRGLADGWRGWTVAMKNGVQWAELAGHDYVLDLVSDLELLRDFPRQKSYFIVGAEGPLAGRGDTRGVFGNCWDSDEDTPTRPQPQDHVAKMPDFDGYCSHKEDGTNGETAAQRWASNRQAVDNTGEPAVPPRELDGYLDSLFDPVLACGDVDLEKPTAIAYRMKGGGQPGSSASEDTPRRLPEPKLKPIPGLDASTLALQQAFIHRQAVLLAREMTLQALALQQQPLSATSRPQLPERPLPPEARPKTVGTGPPAKPVLVRPTPQSLAPGSVAKSPKIPSKPVAAPILARDWTAPESISSSPELVRYSTLNSEHFPQPTQQIKSIIKQYKQPPWAGHPEARRTDGGKVFRRPPDPHEEALMILKGQKTQLAVVPGTQVSREAVALVKPVTSAPRPCMGAAPVQPSRSLEPPEDPVQTQLHRLVNPNFYGYQDAPWRIFLRKEVFYPKDNYSHPVQLDLLFRQILHDTLSEACLRISEDERLQMKALFAQNQLDTQRPLVTESVKRAAINMARDSWEIYFSRLFPAMGSVGTGVQILAVSHTGVKLLRMAKGNREASRRLRVLCAYSFADILFVTMPSQNMLEFNLTNEKVILFSARARQVKTLVDTFILELKKDSDYVVAVRNFLSEDPELLSFHKGDIIHLQSLEPPRIGYSAGCVVRKKLVYLEELRRRGPDFGWRFGAVHGRVGRFPSELVQPAAAPDFLQLPAEPGRGRAAAVAAAVASAAAAREVGRRREGPPVRARSADSGEDSVALPPSTMLEFAQKYFRDPRRRPRDGLKLKSKEDRESKTLEDMLCFTKVPIQESLIELSDSNLNKMAVDMFVAVMRFMGDAPLKGQNELDVLCTLLKFCGDHEVMRDECYCQIVKQITDNTSSKQDSCQRGWRLLYILAAYYSCSEVFYPYLIRFLQHVSWTPGLPFQGIAKACEQNLQKTLRFGGRLEFPSSMELRAMLAGRSSKRQLFLLPGGLERHLKIKTCTVALDVIEGLCSEMALTRPEAFDEYVIFVVTNRGQHVCPLSCQAYILDVASGMEQVDGGYTLWFRRVLWDQPLKFENELYVTMHYNQVLPDYLKGLFSSVPASQPTEQQLQQVSKLASLQHRAKDHFYLPSVREVQEYIPAQLYHTTAGDTWLNLVSQHRQQTQALSPHQARAQFLGLLSAFPLFGSSFFFIQSCSNVLVPAPCILAVNHNGLNFLSTKTHELIVKIPLKEIQSTWTQQPTANSSYPYVEISLGDVAAQRTMQLQLEQGLELCRVVAVHVESMLSAREERLTLPPSEITLL", "length": 3512, "header": "tr|A0A0G2K1F7-1|A0A0G2K1F7_RAT Isoform 1 of Myosin XVA OS=Rattus norvegicus OX=10116 GN=Myo15a PE=3 SV=2 CANONICAL=A0A0G2K1F7-1" }, "isoforms": [ { "isoform_ac": "A0A0G2JTE7-1", "url": "", "sequence": { "sequence": "MAKEEDEEKKAKKGKKGKKAPEPEKPKRSLKGTSRLFMGFRDRTPKISKKGQFRSASAFFWGLHTGPQKTKRKKKARTVLKSTSKLMTQMRVGKKKRAMKGKKPSFMVIRFPGRRGYGRLRPRAQSLSKASTAINWLTKKFLLKKAEESGSEQATLDAWLQRSSSRVGSRKLPFPSGAEILRHGGRLRRFPRSHSIYSSGEPVGFLPFEDEAPFRHAGSRKSLYGLEGFQDLGEYYDYHREGDDYYDQQSLYHYEEQEPYLAGFGGYSPAWPPYDDYGYPSGDPYNYYHPDYYGDTLYPAYGYGYGYGYDDLEPPYAPPSGYSSPYSYHDSFEDEAYPYSYYLDPYATHHMPYPPYDFPHDTPYDIPYFDPYGVPYAEGIYGGGAEAIYPPGVPYVYPEEPAFMYPWVPPPIMSPHNPYAHPMDDIAELEEPEEIGRERQSTSFRLPSAAFFEQQGMDKPARSKLSLIRKFRLFPRPQVKLFGKEKLEVPLPPSLDIPLPLGDAEGEEEEEEMPPVPTMPYTHPYWSFLTPRQRNLQRALSAFGARQGLGFGPEFGPPTPRPATSLARFLKKTLSEKKPIPRLRGSQKARGGRPPVREAAYKRFGYKLAGMDPDRPNTPIVLRRSQPQARNNNNSHGPPSPRPAPRTLTHWSALISPPMPGPSPSPASPLTPPFSPPLSRPPRLASPYSSPYGSLRQHPPPWAAPAHVPFPLQANWWGFAEPPGTSPEVAPDLMAFPVPRPSFRASRSRGAAYGFPRPSLIGSRRRPHLPSPQPSLRSLPGQGYHSPLGHLSPQLSLRRGPFQPPFPPPPRRPQSLRETFSLHRTSGRLGPPRSPVLGSPRPPSPPPLLKHPRHRSLNLPSRLPRTWRRLSEPPTRAVKPWIHRAYHPPPSAGPWGATAGSLEHQENQREPEDSETPWTVPPLAPSWDVDMATTQRPPSPWPEGVGSLRGFSRPPPVPENPLLEHTSPSCEPRPEDQASNLTGIFLGQHHDPGPGQLTKSANPSLENPEEVVISEDPQPSAEPETLNTPPNKTVVSERKALRPSASYPLVTCKQSRATWPQWHRWKTVSRTPAPLAPTRAPGSLLKAGKQLRDKPGRFAVVMPQVRGLSSFQQKGSAPLQPPEHSDQDPEHGPATQACSLRWPRLWSPADTHSPWPRIHTLSSPSPLRGHGGDCQSPKDLWKKTGSRSWQNKMHSIRNLPSVRSREQHREDGVEDMTQLEDLQETTVLTNLKTRFERNLIYTYIGSILVSVNPYRMFAIYGPEQVQQYSGRALGENPPHLFAIANLAFAKMLDAKQNQCVIISGESGSGKTEATKLLLRCLAAMNQRRDVMQQIKILEATPLLEAFGNAKTVRNDNSSRFGKFVEIFLEGGVICGAITSQYLLEKSRIVFQAKNERNYHIFYELLAGLPAQLRQAFSLQEAETYYYLNQGGNCEIAGKSDADDFRRLLAAMEVLGFTSEDQDSIFRILASILHLGNVYFEKHETDAQEVASVVSAREIQAVAELLQVSPEGLQKAITFKVTETIREKIFTPLTVESAVDARDAIAKVLYALLFGWLITRVNALVSPKQDTLSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQEEYIREQMDWREIAFADNQPCINLISLKPYGILRILDDQCCFPQATDHTFLQKCHYHHGANPLYCKPKMPLPEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVHSRTRVVAHLFSSHAAQTAPPRLGKSSSITRLYKAHTVAAKFQQSLLDLVEKMERCNPLFVRCLKPNHKKEPGLFEPDVMMAQLRYSGVLETVRIRKEGFPVRLPFQVFIDRYRCLVALKLNVPADGDMCVSLLSRLCTVTPDMYRVGVSKLFLKEHLHQLLESMRERVLNRAALTLQRYLRGFFTQRRFRSLRQKIILLQSRARGFLARQRYQQMRQSLLKFRSLVHTYVNRRRYLKELSKREVVPVRHLEVPAEVAGLLQAAAGLKPSSVPQVAIVRAPRLQAEPCVTLPLDINNYPMAKFIRCHFKEPSFGMLTVPLKMPLTQMLVEHHAEAISVFKLILRFMGDPHLHGTQEMILGNYIVHQGLVEPALRDEILAQLANQVWRNPNAYNAKRGWLLLAACLSGFAPSSHLDKFLLKFVSDYGQNGFQAVCQHRLLQAMGSGAARTFPPTQLEWTAIQEKASMALDVSCFNGDQFSCPVHPWSTGEAVAGDILKHRGLADGWRGWTVAMKNGVQWAELAGHDYVLDLVSDLELLRDFPRQKSYFIVGAEGPLAGRGDTRGVFGNCWDSDEDTPTRPQPQDHVAKMPDFDGYCSHKEDGTNGETAAQRWASNRQAVDNTGEPAVPPRELDGYLDSLFDPVLACGDVDLEKPTAIAYRMKGGGQPGSSASEDTPRRLPEPKLKPIPGLDASTLALQQAFIHRQAVLLAREMTLQALALQQQPLSATSRPQLPERPLPPEARPKTVGTGPPAKPVLVRPTPQSLAPGSVAKSPKIPSKPVAAPILARDWTAPESISSSPELVRYSTLNSEHFPQPTQQIKSIIKQYKQPPWAGHPEARRTDGGKVFRRPPDPHEEALMILKGQKTQLAVVPGTQVSREAVALVKPVTSAPRPCMGAAPVQPSRSLEPPEDPVQTQLHRLVNPNFYGYQDAPWRIFLRKEVFYPKDNYSHPVQLDLLFRQILHDTLSEACLRISEDERLQMKALFAQNQLDTQRPLVTESVKRAAINMARDSWEIYFSRLFPAMGSVGTGVQILAVSHTGVKLLRMAKGNREASRRLRVLCAYSFADILFVTMPSQNMLEFNLTNEKVILFSARARQVKTLVDTFILELKKDSDYVVAVRNFLSEDPELLSFHKGDIIHLQSLEPPRIGYSAGCVVRKKLVYLEELRRRGPDFGWRFGAVHGRVGRFPSELVQPAAAPDFLQLPAEPGRGRAAAVAAAVASAAAAREVGRRREGPPVRARSADSGEDSVALPPSTMLEFAQKYFRDPRRRPRDGLKLKSKEDRESKTLEDMLCFTKVPIQESLIELSDSNLNKMAVDMFVAVMRFMGDAPLKGQNELDVLCTLLKFCGDHEVMRDECYCQIVKQITDNTSSKQDSCQRGWRLLYILAAYYSCSEVFYPYLIRFLQHVSWTPGLPFQGIAKACEQNLQKTLRFGGRLEFPSSMELRAMLAGRSSKRQLFLLPGGLERHLKIKTCTVALDVIEGLCSEMALTRPEAFDEYVIFVVTNRGQHVCPLSCQAYILDVASGMEQVDGGYTLWFRRVLWDQPLKFENELYVTMHYNQVLPDYLKGLFSSVPASQPTEQQLQQVSKLASLQHRAKDHFYLPSVREVQEYIPAQLYHTTAGDTWLNLVSQHRQQTQALSPHQARAQFLGLLSAFPLFGSSFFFIQSCSNVLVPAPCILAVNHNGLNFLSTKTHELIVKIPLKEIQSTWTQQPTANSSYPYVEISLGDVAAQRTMQLQLEQGLELCRVVAVHVESMLSAREERLTLPPSEITLL", "length": 3494, "header": "tr|A0A0G2JTE7-1|A0A0G2K1F7_RAT Computationally mapped isoform of Myosin XVA OS=Rattus norvegicus OX=10116 GN=Myo15a PE=3 SV=2 CANONICAL=A0A0G2K1F7-1" }, "locus": { "chromosome": "10", "start_pos": 45334642, "end_pos": 45278737, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000079133.2", "url": "https://www.ensembl.org/id/ENSRNOT00000079133.2" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000068681.2", "url": "https://www.ensembl.org/id/ENSRNOP00000068681.2" } ] } }, { "isoform_ac": "A0A0G2K1F7-1", "url": "", "sequence": { "sequence": "MAKEEDEEKKAKKGKKGKKAPEPEKPKRSLKGTSRLFMGFRDRTPKISKKGQFRSASAFFWGLHTGPQKTKRKKKARTVLKSTSKLMTQMRVGKKKRAMKGKKPSFMVIRFPGRRGYGRLRPRAQSLSKASTAINWLTKKFLLKKAEESGSEQATLDAWLQRSSSRVGSRKLPFPSGAEILRHGGRLRRFPRSHSIYSSGEPVGFLPFEDEAPFRHAGSRKSLYGLEGFQDLGEYYDYHREGDDYYDQQSLYHYEEQEPYLAGFGGYSPAWPPYDDYGYPSGDPYNYYHPDYYGDTLYPAYGYGYGYGYDDLEPPYAPPSGYSSPYSYHDSFEDEAYPYSYYLDPYATHHMPYPPYDFPHDTPYDIPYFDPYGVPYAEGIYGGGAEAIYPPGVPYVYPEEPAFMYPWVPPPIMSPHNPYAHPMDDIAELEEPEEIGRERQSTSFRLPSAAFFEQQGMDKPARSKLSLIRKFRLFPRPQVKLFGKEKLEVPLPPSLDIPLPLGDAEGEEEEEEMPPVPTMPYTHPYWSFLTPRQRNLQRALSAFGARQGLGFGPEFGPPTPRPATSLARFLKKTLSEKKPIPRLRGSQKARGGRPPVREAAYKRFGYKLAGMDPDRPNTPIVLRRSQPQARNNNNSHGPPSPRPAPRTLTHWSALISPPMPGPSPSPASPLTPPFSPPLSRPPRLASPYSSPYGSLRQHPPPWAAPAHVPFPLQANWWGFAEPPGTSPEVAPDLMAFPVPRPSFRASRSRGAAYGFPRPSLIGSRRRPHLPSPQPSLRSLPGQGYHSPLGHLSPQLSLRRGPFQPPFPPPPRRPQSLRETFSLHRTSGRLGPPRSPVLGSPRPPSPPPLLKHPRHRSLNLPSRLPRTWRRLSEPPTRAVKPWIHRAYHPPPSAGPWGATAGSLEHQENQREPEDSETPWTVPPLAPSWDVDMATTQRPPSPWPEGVGSLRGFSRPPPVPENPLLEHTSPSCEPRPEDQASNLTGIFLGQHHDPGPGQLTKSANPSLENPEEVVISEDPQPSAEPETLNTPPNKTVVSERKALRPSASYPLVTCKQSRATWPQWHRWKTVSRTPAPLAPTRAPGSLLKAGKQLRDKPGRFAVVMPQVRGLSSFQQKGSAPLQPPEHSDQDPEHGPATQACSLRWPRLWSPADTHSPWPRIHTLSSPSPLRGHGGDCQSPKDLWKKTGSRSWQNKMHSIRNLPSVRSREQHREDGVEDMTQLEDLQETTVLTNLKTRFERNLIYTYIGSILVSVNPYRMFAIYGPEQVQQYSGRALGENPPHLFAIANLAFAKMLDAKQNQCVIISGESGSGKTEATKLLLRCLAAMNQRRDVMQQIKILEATPLLEAFGNAKTVRNDNSSRFGKFVEIFLEGGVICGAITSQYLLEKSRIVFQAKNERNYHIFYELLAGLPAQLRQAFSLQEAETYYYLNQGGNCEIAGKSDADDFRRLLAAMEVLGFTSEDQDSIFRILASILHLGNVYFEKHETDAQEVASVVSAREIQAVAELLQVSPEGLQKAITFKVTETIREKIFTPLTVESAVDARDAIAKVLYALLFGWLITRVNALVSPKQDTLSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQEEYIREQMDWREIAFADNQPCINLISLKPYGILRILDDQCCFPQATDHTFLQKCHYHHGANPLYCKPKMPLPEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVHSRTRVVAHLFSSHAAQTAPPRLGKSSSITRLYKAHTVAAKFQQSLLDLVEKMERCNPLFVRCLKPNHKKEPGLFEPDVMMAQLRYSGVLETVRIRKEGFPVRLPFQVFIDRYRCLVALKLNVPADGDMCVSLLSRLCTVTPDMYRVGVSKLFLKEHLHQLLESMRERVLNRAALTLQRYLRGFFTQRRFRSLRQKIILLQSRARGFLARQRYQQMRQSLLKFRSLVHTYVNRRRYLKLRAERRRRAQEAWLREQEELSKREVVPVRHLEVPAEVAGLLQAAAGLKPSSVPQVAIVRAPRLQAEPCVTLPLDINNYPMAKFIRCHFKEPSFGMLTVPLKMPLTQMLVEHHAEAISVFKLILRFMGDPHLHGTQEMILGNYIVHQGLVEPALRDEILAQLANQVWRNPNAYNAKRGWLLLAACLSGFAPSSHLDKFLLKFVSDYGQNGFQAVCQHRLLQAMGSGAARTFPPTQLEWTAIQEKASMALDVSCFNGDQFSCPVHPWSTGEAVAGDILKHRGLADGWRGWTVAMKNGVQWAELAGHDYVLDLVSDLELLRDFPRQKSYFIVGAEGPLAGRGDTRGVFGNCWDSDEDTPTRPQPQDHVAKMPDFDGYCSHKEDGTNGETAAQRWASNRQAVDNTGEPAVPPRELDGYLDSLFDPVLACGDVDLEKPTAIAYRMKGGGQPGSSASEDTPRRLPEPKLKPIPGLDASTLALQQAFIHRQAVLLAREMTLQALALQQQPLSATSRPQLPERPLPPEARPKTVGTGPPAKPVLVRPTPQSLAPGSVAKSPKIPSKPVAAPILARDWTAPESISSSPELVRYSTLNSEHFPQPTQQIKSIIKQYKQPPWAGHPEARRTDGGKVFRRPPDPHEEALMILKGQKTQLAVVPGTQVSREAVALVKPVTSAPRPCMGAAPVQPSRSLEPPEDPVQTQLHRLVNPNFYGYQDAPWRIFLRKEVFYPKDNYSHPVQLDLLFRQILHDTLSEACLRISEDERLQMKALFAQNQLDTQRPLVTESVKRAAINMARDSWEIYFSRLFPAMGSVGTGVQILAVSHTGVKLLRMAKGNREASRRLRVLCAYSFADILFVTMPSQNMLEFNLTNEKVILFSARARQVKTLVDTFILELKKDSDYVVAVRNFLSEDPELLSFHKGDIIHLQSLEPPRIGYSAGCVVRKKLVYLEELRRRGPDFGWRFGAVHGRVGRFPSELVQPAAAPDFLQLPAEPGRGRAAAVAAAVASAAAAREVGRRREGPPVRARSADSGEDSVALPPSTMLEFAQKYFRDPRRRPRDGLKLKSKEDRESKTLEDMLCFTKVPIQESLIELSDSNLNKMAVDMFVAVMRFMGDAPLKGQNELDVLCTLLKFCGDHEVMRDECYCQIVKQITDNTSSKQDSCQRGWRLLYILAAYYSCSEVFYPYLIRFLQHVSWTPGLPFQGIAKACEQNLQKTLRFGGRLEFPSSMELRAMLAGRSSKRQLFLLPGGLERHLKIKTCTVALDVIEGLCSEMALTRPEAFDEYVIFVVTNRGQHVCPLSCQAYILDVASGMEQVDGGYTLWFRRVLWDQPLKFENELYVTMHYNQVLPDYLKGLFSSVPASQPTEQQLQQVSKLASLQHRAKDHFYLPSVREVQEYIPAQLYHTTAGDTWLNLVSQHRQQTQALSPHQARAQFLGLLSAFPLFGSSFFFIQSCSNVLVPAPCILAVNHNGLNFLSTKTHELIVKIPLKEIQSTWTQQPTANSSYPYVEISLGDVAAQRTMQLQLEQGLELCRVVAVHVESMLSAREERLTLPPSEITLL", "length": 3512, "header": "tr|A0A0G2K1F7-1|A0A0G2K1F7_RAT Isoform 1 of Myosin XVA OS=Rattus norvegicus OX=10116 GN=Myo15a PE=3 SV=2 CANONICAL=A0A0G2K1F7-1" }, "locus": { "chromosome": "10", "start_pos": 45334642, "end_pos": 45278737, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000086083.2", "url": "https://www.ensembl.org/id/ENSRNOT00000086083.2" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000071821.2", "url": "https://www.ensembl.org/id/ENSRNOP00000071821.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "rno:501699", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:501699", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q9QZZ4-1", "protein_name": "Unconventional myosin-XV", "gene_name": "Myo15a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADEEKKAKKGKKGKKAPEPEKPKRSLKGTSRLFMGFRDRTPKISKKGQFRSASAFFWGLHTGPQKTKRKKKARTVLKSTSKLMTQMRVGKKKRAMKGKKPSFMVIRFPGRRGYGRLRPRAQSLSKASTAINWLTKKFLLKKAEESGSEQATVDAWLQRSSSRVGSRKLPFPSGAEILRHGGRLRRFPRSHSIYSSGEPVGFLPFEDEAPFRHAGSRKSLYGLEGFQDLGEYYDYHREGDDYYDQQSLYHYEEQEPYLAEFGGYSPAWPPYDDYGYPPGDPYNYYHPDYYGDTLYPGYAYGYGYGYDDFEPPYAPPSGYSSPYSYHDSFESEAYPYSYYLDPYATHHMPYPPYDFPYDTPYDIPYFDPYGVPYAEGVYGGGAEAIYPPGMPYVYPEEPAFMYPWVPPPIMSPHNPYAHPMDDIAELEEPEETGEERQSTSFRLPSAAFFEQQGMDKPARSKLSLIRKFRLFPRPQVKLFGKEKLEVPLPPSLDIPLPLGDAEGEEEEEEMPPVPTMPYTHPYWSFLTPRQRNLQRALSAFGARQGLGFGPEFGHPTPRPATSLARFLKKTLSEKKPIPRLRGSQKARGGRPPVREAAYKRFGYKLAGMDPDRPNTPIVLRRSQPQARNNNNSHGPPSPRPAPRALTHWSALISPPMPAPSPSPASPLTPPFSPTFSRPPRLASPYGSLRQHPPPWAAPAHVPFPPQANWWGFAEPPGTSPEVAPDLLAFPVPRPSFRASRSRSRRAAYGFPSPSLIGSRRRPHLPSPQPSLRSLPGQGYHSPLGPLSPQLSLRRGPFQPPFPPPPRRPQSLREAFSLRRASGRLGPPRSPVLGSPRPPSPPPLLKHGPRHRSLNLPSRLPRTWRRLSEPPTRAVKPWVHRAYPPPPSAGPWGASTGALEQQENQREAEDSETPWTVPPLAPSWDVDMPPTQRPPSPWPEGIGSLRGFSRPPPVPENPLLEHTSPSCEPQSEDRVSNLTGIFLGQHHDPGPGQLTKSADPSLEKPEEVVTLGDPQPPAEPEALNPTPPNKNVVSERKVLRLSASYPLVTCKQARATWPQWHRWKTVSRTPAPLAPTRAPGPLLKAGEQPRAEPGRFAVVMPQVRGVSSFRPKGPAPVQPPEHPDQDPEQGPAPQACSLRWPRLWPPTDAHCLWSRIRTYSSQSHLRGHGGDCHKSLWKKTRPQSWQNKMHSIRNLPSMRSREQHREDGVEDMTQLEDLQETTVLANLKTRFERNLIYTYIGSILVSVNPYRMFAIYGPEQVQQYSGRALGENPPHLFAIANLAFAKMLDAKQNQCVIISGESGSGKTEATKLILRCLAAMNQRRDVMQQIKILEATPLLEAFGNAKTVRNDNSSRFGKFVEIFLEGGVICGAITSQYLLEKSRIVFQAKNERNYHIFYELLAGLPAQLRQAFSLQEAETYYYLNQGGNCEIAGKSDADDFRRLLAAMEVLGFTSEDQDSIFRILASILHLGNVYFEKHETDAQEVASVVSAREIQAVAELLQVSPEGLQKAITFKVTETIREKIFTPLTVESAVDARDAIAKVLYALLFGWLITRVNALVSPKQDTLSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQEEYIREQMDWREIAFADNQPCINLISLKPYGILRILDDQCCFPQATDHTFLQKCHYHHGANPLYSKPKMPLPEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVHSRTRVVAHLFSSHAAQTAPPRLGKSSSITRLYKAHTVAAKFQQSLLDLVEKMERCNPLFVRCLKPNHKKEPGLFEPDVMMAQLRYSGVLETVRIRKEGFPVRLPFQVFIDRYRCLVALKLNVPADGDMCVSLLSRLCTVTPDMYRVGISKLFLKEHLHQLLESMRERVQNRAALTLQRYLRGFFIQRHFRSLRRKIILLQSRARGFLARQRYQQMRQSLLKFRSLVHTYVNRRRYLKLRAEQRRRAQEAWLREQEELSKREVVPVRHLEVPAEVAGLLQAAAGLKLSSGPRVAVVRAPRLQAEPCVTLPLDINNYPMAKFIRCHFKEPSFGMLTVPLKMPLTRLPVEHHAEAISVFKLILRFMGDPHLHGTQEMILGNYIVHQGLVEPALRDEILAQLANQVWRNPNAYNSKRGWLLLAACLSGFAPSPHLDKFLLKFVSDYGQNGFQAVCQHRLLQAMGSGAARTFPPTQLEWTAIQEKASMALDVSCFNGDQFSCPVHTWSTGEAVAGDILKHRGLADGWRGWTVAMKNGVQWAELAGHDYVLDLVSDLELLRDFPRQKSYFIVGAEGPLAGRGDTRGVFGNCWDSDEDTPTRPQPQDHVAKMPDLDGYCSHKEDGTNGETEAQRWTSNRQAVDSIGESTVPPRELDGYLDSLFDPVLACGDADLEKPTAIAYRMKGGGQPGGGGGSTSEDTSRRPPEPKLKPIPGLDASTLALQQAFIHRQAVLLAREMTLQALALQQQPLSATSRPQLPERPLAPEARPKTVVGTGPPAKPVLVRPTPQSWAPGSVAKAPKIPSKPVAVPILAQDWTAPESISASPELVRYSTLNSEHFPQPTQQIRSIIKQYKQPPWAGHPEARRTDGGKVFRRPPDPHEEALMILKGQKTQLAVVPGTQVSREAVAMVKPVTSAPRPCMGPTPVQPSRSLEPPEDPVQTQLHRLVNPNFYGYQDIPWRIFLRKEVFYPKDNYSHPVQLDLLFRQILHDTFSEACLRISEDERLQMKALFAQNQLDTQRPLVTESVKRAAISMARDSWEIYFSRLFPAMGSVGTGVQILAVSHTGIKLLQMVKGSKEASRRLRVLCAYSFADILFVTMPSQNMLEFNLSNEKLILFSARAQQVKTLVDTFILELKKDSDYVVAVRNFLSEDPELLSFHKGDIIHLQSLEPTRVGYSAGCVVRKKLVYLEELRRRGPDFGWRFGAVHGRVGRFPSELVQPAAAPDFLQLPAEPGRGRAAAVAAAVASAAAAQEVGRRREGPPVRARSADSGEDSIALPPSTMLEFAQKYFRDPRRRPRDGLKLKSKEDRESKTLEDVLCFTKVPIQESLIELSDSNLNKMAVDMFVAVMRFMGDAPLKGQSELDVLCTLLKLCGDHEVMRDECYCQIVKQITDNSSPKQDSCQRGWRLLYIMAAYYSCSEVFYPYLIRFLQHVSWTPGLPFQGIAKACEQNLQKTLRFGGRLEFPSNMELRAMLAGRSSKRQLFLLPGGLERHLKIKTCTVALDVIEGLCTEMALTRPEAFDEYVIFVVTNRGQHVCPLSCRAYILDVASEMEQVDGGYTLWFRRVLWDQPLKFENELYVTMHYNQVLPDYLKGLFSSVPARQPTEQQLQQVSKLASLQHRAKDHFYLPSVREVQEYIPAQLYHTTAGDTWLNLVSQHRQQTQALSPHQARAQFLGLLSAFPLFGSSFFFIQSCSNVLVPAPCILAVNHNGLNFLSTKTHELIVKIPLKEIQSTWTQQPTANSSYPYVEISLGDVAAQRTMQLQLEQGLELCRVVAVHVESMLSAREERLTLPPSEITLL", "length": 3511 }, "evidence": [ { "id": "45229515", "url": "http://www.informatics.jax.org/homology/45229515", "database": "MGI" } ], "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UKN7-1", "protein_name": "Unconventional myosin-XV", "gene_name": "MYO15A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKEEDEEKKAKKGKKGKKAPEPEKPKRSLKGTSRLFMGFRDRTPKISKKGQFRSASAFFWGLHTGPQKTKRKRKARTVLKSTSKLMTQMRMGKKKRAMKGKKPSFMVIRFPGRRGYGRLRPRARSLSKASTAINWLTKKFLLKKAEESGSEQATVDAWLQRSSSRMGSRKLPFPSGAEILRPGGRLRRFPRSRSIYASGEPLGFLPFEDEAPFHHSGSRKSLYGLEGFQDLGEYYDYHRDGDDYYDRQSLHRYEEQEPYLAGLGPYSPAWPPYGDHYYGYPPEDPYDYYHPDYYGGPFDPGYTYGYGYDDYEPPYAPPSGYSSPYSYHDGYEGEAHPYGYYLDPYAPYDAPYPPYDLPYHTPYDVPYFDPYGVHYTVPYAEGVYGGGDEAIYPPEVPYFYPEESASAFVYPWVPPPIPSPHNPYAHAMDDIAELEEPEDAGVERQGTSFRLPSAAFFEQQGMDKPARSKLSLIRKFRLFPRPQVKLFGKEKLEVPLPPSLDIPLPLGDADEEEDEEELPPVSAVPYGHPFWGFLTPRQRNLQRALSAFGAHRGLGFGPEFGRPVPRPATSLARFLKKTLSEKKPIARLRGSQKARAGGPAVREAAYKRFGYKLAGMDPEKPGTPIVLRRAQPRARSSNDARRPPAPQPAPRTLSHWSALLSPPVPPRPPSSGPPPAPPLSPALSGLPRPASPYGSLRRHPPPWAAPAHVPPAPQASWWAFVEPPAVSPEVPPDLLAFPGPRPSFRGSRRRGAAFGFPGASPRASRRRAWSPLASPQPSLRSSPGLGYCSPLAPPSPQLSLRTGPFQPPFLPPARRPRSLQESPAPRRAAGRLGPPGSPLPGSPRPPSPPLGLCHSPRRSSLNLPSRLPHTWRRLSEPPTRAVKPQVRLPFHRPPRAGAWRAPLEHRESPREPEDSETPWTVPPLAPSWDVDMPPTQRPPSPWPGGAGSRRGFSRPPPVPENPFLQLLGPVPSPTLQPEDPAADMTRVFLGRHHEPGPGQLTKSAGPTPEKPEEEATLGDPQLPAETKPPTPAPPKDVTPPKDITPPKDVLPEQKTLRPSLSYPLAACDQTRATWPPWHRWGTLPQAAAPLAPIRAPEPLPKGGERRQAAPGRFAVVMPRVQKLSSFQRVGPATLKPQVQPIQDPKPRACSLRWSCLWLRADAYGPWPRVHTHPQSCHLGPGAACLSLRGSWEEVGPPSWRNKMHSIRNLPSMRFREQHGEDGVEDMTQLEDLQETTVLSNLKIRFERNLIYTYIGSILVSVNPYQMFGIYGPEQVQQYNGRALGENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLAAMNQKREVMQQIKILEATPLLESFGNAKTVRNDNSSRFGKFVEIFLEGGVISGAITSQYLLEKSRIVFQAKNERNYHIFYELLAGLPAQLRQAFSLQEAETYYYLNQGGNCEIAGKSDADDFRRLLAAMEVLGFSSEDQDSIFRILASILHLGNVYFEKYETDAQEVASVVSAREIQAVAELLQISPEGLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLYALLFSWLITRVNALVSPRQDTLSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQEEYIREQIDWQEITFADNQPCINLISLKPYGILRILDDQCCFPQATDHTFLQKCHYHHGANPLYSKPKMPLPEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTRVVAHLFSSHAPQAAPQRLGKSSSVTRLYKAHTVAAKFQQSLLDLVEKMERCNPLFMRCLKPNHKKEPGLFEPDVVMAQLRYSGVLETVRIRKEGFPVRLPFQGFIDRYCCLVALKHDLPANGDMCVSVLSRLCKVMPNMYRVGVSKLFLKEHLYQLLESMREHVLNLAALTLQRCLRGFFIKRRFRSLRHKIILLQSRARGYLARQRYQQMRRSLVKFRSLVHAYVSRRRYLKLRAEWRCQVEGALLWEQEELSKREVVAVGHLEVPAELAGLLQAVAGLGLAQVPQVAPVRTPRLQAEPRVTLPLDINNYPMAKFVQCHFKEPAFGMLTVPLRTPLTQLPAEHHAEAVSIFKLILRFMGDPHLHGARENIFGNYIVQKGLAVPELRDEILAQLANQVWHNHNAHNAERGWLLLAACLSGFAPSPCFNKYLLKFVSDYGRNGFQAVCQHRLMQAMGRAQQQGSGAARTLPPTQLEWTATYEKASMALDVGCFNGDQFSCPVHSWSTGEEVAGDILRHRGLADGWRGWTVAMKNGVQWAELAGHDYVLDLVSDLELLRDFPRQKSYFIVGTEGPAASRGGPKVVFGNSWDSDEDMSTRPQPQEHMPKVLDSDGYSSHNQDGTNGETEAQRGTATHQESDSLGEPAVPHKGLDCYLDSLFDPVLSYGDADLEKPTAIAYRMKGGGQPGGGSSSGTEDTPRRPPEPKPIPGLDASTLALQQAFIHKQAVLLAREMTLQATALQQQPLSAALRSLPAEKPPAPEAQPTSVGTGPPAKPVLLRATPKPLAPAPLAKAPRLPIKPVAAPVLAQDQASPETTSPSPELVRYSTLNSEHFPQPTQQIKNIVRQYQQPFRGGRPEALRKDGGKVFMKRPDPHEEALMILKGQMTHLAAAPGTQVSREAVALVKPVTSAPRPSMAPTSALPSRSLEPPEELTQTRLHRLINPNFYGYQDAPWKIFLRKEVFYPKDSYSHPVQLDLLFRQILHDTLSEACLRISEDERLRMKALFAQNQLDTQKPLVTESVKRAVVSTARDTWEVYFSRIFPATGSVGTGVQLLAVSHVGIKLLRMVKGGQEAGGQLRVLRAYSFADILFVTMPSQNMLEFNLASEKVILFSARAHQVKTLVDDFILELKKDSDYVVAVRNFLPEDPALLAFHKGDIIHLQPLEPPRVGYSAGCVVRRKVVYLEELRRRGPDFGWRFGTIHGRVGRFPSELVQPAAAPDFLQLPTEPGRGRAAAVAAAVASAAAAQEVGRRREGPPVRARSADHGEDALALPPYTMLEFAQKYFRDPQRRPQDGLRLKSKEPRESRTLEDMLCFTKTPLQESLIELSDSSLSKMATDMFLAVMRFMGDAPLKGQSDLDVLCNLLKLCGDHEVMRDECYCQVVKQITDNTSSKQDSCQRGWRLLYIVTAYHSCSEVLHPHLTRFLQDVSRTPGLPFQGIAKACEQNLQKTLRFGGRLELPSSIELRAMLAGRSSKRQLFLLPGGLERHLKIKTCTVALDVVEEICAEMALTRPEAFNEYVIFVVTNRGQHVCPLSRRAYILDVASEMEQVDGGYMLWFRRVLWDQPLKFENELYVTMHYNQVLPDYLKGLFSSVPASRPSEQLLQQVSKLASLQHRAKDHFYLPSVREVQEYIPAQLYRTTAGSTWLNLVSQHRQQTQALSPHQARAQFLGLLSALPMFGSSFFFIQSCSNIAVPAPCILAINHNGLNFLSTETHELMVKFPLKEIQSTRTQRPTANSSYPYVEIALGDVAAQRTLQLQLEQGLELCRVVAVHVENLLSAHEKRLTLPPSEITLL", "length": 3530 }, "evidence": [ { "id": "45229515", "url": "http://www.informatics.jax.org/homology/45229515", "database": "MGI" } ], "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K1F7", "url": "https://www.uniprot.org/uniprot/A0A0G2K1F7" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K1F7", "url": "https://www.uniprot.org/uniprot/A0A0G2K1F7" } ], "pmid": "" }, { "name": "microfilament motor activity", "id": "GO:0000146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000146", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K1F7", "url": "https://www.uniprot.org/uniprot/A0A0G2K1F7" } ], "pmid": "" }, { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K1F7", "url": "https://www.uniprot.org/uniprot/A0A0G2K1F7" } ], "pmid": "" }, { "name": "cytoskeletal motor activity", "id": "GO:0003774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003774", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K1F7", "url": "https://www.uniprot.org/uniprot/A0A0G2K1F7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K1F7", "url": "https://www.uniprot.org/uniprot/A0A0G2K1F7" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K1F7", "url": "https://www.uniprot.org/uniprot/A0A0G2K1F7" } ], "pmid": "" }, { "name": "vesicle", "id": "GO:0031982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031982", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K1F7", "url": "https://www.uniprot.org/uniprot/A0A0G2K1F7" } ], "pmid": "" }, { "name": "stereocilium bundle", "id": "GO:0032421", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032421", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K1F7", "url": "https://www.uniprot.org/uniprot/A0A0G2K1F7" } ], "pmid": "" }, { "name": "stereocilium", "id": "GO:0032420", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032420", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K1F7", "url": "https://www.uniprot.org/uniprot/A0A0G2K1F7" } ], "pmid": "" }, { "name": "myosin complex", "id": "GO:0016459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016459", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K1F7", "url": "https://www.uniprot.org/uniprot/A0A0G2K1F7" } ], "pmid": "" }, { "name": "actin-based cell projection", "id": "GO:0098858", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098858", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K1F7", "url": "https://www.uniprot.org/uniprot/A0A0G2K1F7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K1F7", "url": "https://www.uniprot.org/uniprot/A0A0G2K1F7" } ], "pmid": "" }, { "name": "locomotory behavior", "id": "GO:0007626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007626", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K1F7", "url": "https://www.uniprot.org/uniprot/A0A0G2K1F7" } ], "pmid": "" }, { "name": "inner ear morphogenesis", "id": "GO:0042472", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042472", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K1F7", "url": "https://www.uniprot.org/uniprot/A0A0G2K1F7" } ], "pmid": "" }, { "name": "sensory perception of sound", "id": "GO:0007605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007605", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K1F7", "url": "https://www.uniprot.org/uniprot/A0A0G2K1F7" } ], "pmid": "" }, { "name": "vesicle transport along actin filament", "id": "GO:0030050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030050", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K1F7", "url": "https://www.uniprot.org/uniprot/A0A0G2K1F7" } ], "pmid": "" }, { "name": "response to light stimulus", "id": "GO:0009416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009416", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K1F7", "url": "https://www.uniprot.org/uniprot/A0A0G2K1F7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1031, "end_pos": 1033, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1356, "end_pos": 1358, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2685, "end_pos": 2687, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2820, "end_pos": 2822, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3106, "end_pos": 3108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3454, "end_pos": 3456, "annotation": "n_glycosylation_sequon" }, { "start_pos": 633, "end_pos": 635, "annotation": "n_glycosylation_sequon" }, { "start_pos": 980, "end_pos": 982, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "synthesized_glycans": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.mgi", "label": "MGI Homologs" } ], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }