{ "uniprot_canonical_ac": "A0A0G2K1A4-1", "uniprot_ac": "A0A0G2K1A4", "uniprot_id": "A0A0G2K1A4_RAT", "mass": { "chemical_mass": 93726.0, "monoisotopic_mass": 93726.0 }, "refseq": {}, "gene_names": [ { "name": "Evi5l", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A0A0G2K1A4", "id": "A0A0G2K1A4" } ], "protein_names": [ { "name": "Ecotropic viral integration site 5-like", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "A0A0G2K1A4" } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K1A4", "url": "https://www.uniprot.org/uniprot/A0A0G2K1A4" } ], "common_name": "Rat" } ], "gene": [ { "name": "Evi5l", "url": "https://www.uniprot.org/uniprot/A0A0G2K1A4", "locus": { "chromosome": "12", "start_pos": 2559950, "end_pos": 2519671, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSRNOG00000001034", "url": "https://www.ensembl.org/id/ENSRNOG00000001034" } ] } } ], "crossref": [ { "id": "ENSRNOG00000001034", "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000001034", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "IPR000195", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000195", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "SECWTEV", "url": "https://omabrowser.org/oma/group/SECWTEV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR47219", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47219", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47219:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47219:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00566", "url": "http://pfam.xfam.org/family/PF00566", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "1561962", "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1561962", "database": "RGD", "categories": [ "Organism-specific" ] }, { "id": "A0A0G2JX24", "url": "https://www.uniprot.org/uniprot/A0A0G2JX24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0G2JX24-1", "url": "https://www.uniprot.org/uniprot/A0A0G2JX24-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0G2K1A4", "url": "https://www.uniprot.org/uniprot/A0A0G2K1A4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0G2K1A4-1", "url": "https://www.uniprot.org/uniprot/A0A0G2K1A4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I6AHD4", "url": "https://www.uniprot.org/uniprot/A0A8I6AHD4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I6AHD4-1", "url": "https://www.uniprot.org/uniprot/A0A8I6AHD4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "D3ZCJ7", "url": "https://www.uniprot.org/uniprot/D3ZCJ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "D3ZCJ7-1", "url": "https://www.uniprot.org/uniprot/D3ZCJ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "D3ZXM4", "url": "https://www.uniprot.org/uniprot/D3ZXM4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "D3ZXM4-1", "url": "https://www.uniprot.org/uniprot/D3ZXM4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLSTMASPTLSPDSSSQEALSAPTCSPTSDSENLSPDELELLAKLEEQNRLLEADSKSMRSMNGSRRNSGSSLVSSSSASSNLSHLEEDTWILWGRIANEWEEWRRRKEKLLKELIRKGIPHHFRAIVWQLLCSATDMPVKNQYSELLKMSSPCEKLIRRDIARTYPEHEFFKGQDSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVGLLLMQMPEEEAFCVFVRLMQEYRLRELFKPSMAELGLCIYQFEYMLQEQLPDLNTHFRSQSFHTSMYASSWFLTLFLTTFPLPVATRVFDIFMYEGLEIVFRVGLALLQVNQTELMQLDMEGMSQYFQRVIPHQFDSCPDKLVLKAYQVKYNPKKMKRLEKEYAAMKSKEMEEQIEIKRLRTENRLLKQRIETLEKESAALADRLIQGQVTRAQEAEENYVIKRELAVVRQQCSSTAEDLQKAQSTIRQLQEQQENPRLTEDFVSHLETELEQSRLRETETLGALREMQDKVLDMEKRNSSLPDENNVARLQEELKALKVREGEAVASARELKLQLQELSDTWQAHVSRGGRWKESPRKLVLGELQDELMTMRLREAQALADGREWRQRVVELETQDNIHRNLLNRVEAERAALQEKLQYLAAQNKGLQTQLSESRRKQAEAECKSKEEVMAVRLREADSMAAVAEMRQRIAELEIQREEGRIQGQLNHSDSSQYIRELKDQIEELKTEVRLLKGPPTFEDPLAFDGLSLTRHLDEDSLPSSDEELLGVGVGVGVGAALQDPLYPLSPRDARFFRSLDRPAKDSEGSSDSDADELATPYSNQVLDN", "length": 815, "header": "tr|A0A0G2K1A4-1|A0A0G2K1A4_RAT Isoform 1 of Ecotropic viral integration site 5-like OS=Rattus norvegicus OX=10116 GN=Evi5l PE=4 SV=2 CANONICAL=A0A0G2K1A4-1" }, "isoforms": [ { "isoform_ac": "A0A0G2JX24-1", "url": "", "sequence": { "sequence": "MSLSTMASPTLSPDSSSQEALSAPTCSPTSDSENLSPDELELLAKLEEQNRLLEADSKSMRSMNGSRRNSGSSLVSSSSASSNLSHLEEDTWILWGRIANEWEEWRRRKEKLLKELIRKGIPHHFRAIVWQLLCSATDMPVKNQYSELLKMSSPCEKLIRRDIARTYPEHEFFKGQDSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVGLLLMQMPEEEAFCVFVRLMQEYRLRELFKPSMAELGLCIYQFEYMLQEQLPDLNTHFRSQSFHTSMYASSWFLTLFLTTFPLPVATRVFDIFMYEGLEIVFRVGLALLQVNQTELMQLDMEGMSQYFQRVIPHQFDSCPDKLVLKAYQVKYNPKKMKRLEKEYAAMKSKEMEEQIEIKRLRTENRLLKQRIETLEKGQVTRAQEAEENYVIKRELAVVRQQCSSTAEDLQKAQSTIRQLQEQQENPRLTEDFVSHLETELEQSRLRETETLGALREMQDKVLDMEKRNSSLPDENNVARLQEELKALKVREGEAVASARELKLQLQELSDTWQAHVSRGGRWKESPRKLVLGELQDELMTMRLREAQALADGREWRQRVVELETQDNIHRNLLNRVEAERAALQEKLQYLAAQNKGLQTQLSESRRKQAEAECKSKEEVMAVRLREADSMAAVAEMRQRIAELEIQREEGRIQGQLNHSDSSQYIRELKDQIEELKTEVRLLKGPPTFEDPLAFDGLSLTRHLDEDSLPSSDEELLGVGVGVGVGAALQDPLYPLSPRDARFFRSLDRPAKDSEGSSDSDADELATPYSNQVLDN", "length": 804, "header": "tr|A0A0G2JX24-1|A0A0G2K1A4_RAT Computationally mapped isoform of Ecotropic viral integration site 5-like OS=Rattus norvegicus OX=10116 GN=Evi5l PE=4 SV=2 CANONICAL=A0A0G2K1A4-1" }, "locus": { "chromosome": "12", "start_pos": 2557342, "end_pos": 2535072, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000077396.2", "url": "https://www.ensembl.org/id/ENSRNOT00000077396.2" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000070107.2", "url": "https://www.ensembl.org/id/ENSRNOP00000070107.2" } ] } }, { "isoform_ac": "A0A0G2K1A4-1", "url": "", "sequence": { "sequence": "MSLSTMASPTLSPDSSSQEALSAPTCSPTSDSENLSPDELELLAKLEEQNRLLEADSKSMRSMNGSRRNSGSSLVSSSSASSNLSHLEEDTWILWGRIANEWEEWRRRKEKLLKELIRKGIPHHFRAIVWQLLCSATDMPVKNQYSELLKMSSPCEKLIRRDIARTYPEHEFFKGQDSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVGLLLMQMPEEEAFCVFVRLMQEYRLRELFKPSMAELGLCIYQFEYMLQEQLPDLNTHFRSQSFHTSMYASSWFLTLFLTTFPLPVATRVFDIFMYEGLEIVFRVGLALLQVNQTELMQLDMEGMSQYFQRVIPHQFDSCPDKLVLKAYQVKYNPKKMKRLEKEYAAMKSKEMEEQIEIKRLRTENRLLKQRIETLEKESAALADRLIQGQVTRAQEAEENYVIKRELAVVRQQCSSTAEDLQKAQSTIRQLQEQQENPRLTEDFVSHLETELEQSRLRETETLGALREMQDKVLDMEKRNSSLPDENNVARLQEELKALKVREGEAVASARELKLQLQELSDTWQAHVSRGGRWKESPRKLVLGELQDELMTMRLREAQALADGREWRQRVVELETQDNIHRNLLNRVEAERAALQEKLQYLAAQNKGLQTQLSESRRKQAEAECKSKEEVMAVRLREADSMAAVAEMRQRIAELEIQREEGRIQGQLNHSDSSQYIRELKDQIEELKTEVRLLKGPPTFEDPLAFDGLSLTRHLDEDSLPSSDEELLGVGVGVGVGAALQDPLYPLSPRDARFFRSLDRPAKDSEGSSDSDADELATPYSNQVLDN", "length": 815, "header": "tr|A0A0G2K1A4-1|A0A0G2K1A4_RAT Isoform 1 of Ecotropic viral integration site 5-like OS=Rattus norvegicus OX=10116 GN=Evi5l PE=4 SV=2 CANONICAL=A0A0G2K1A4-1" }, "locus": { "chromosome": "12", "start_pos": 2557342, "end_pos": 2535072, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000079918.2", "url": "https://www.ensembl.org/id/ENSRNOT00000079918.2" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000071761.2", "url": "https://www.ensembl.org/id/ENSRNOP00000071761.2" } ] } }, { "isoform_ac": "A0A8I6AHD4-1", "url": "", "sequence": { "sequence": "MSLSTMASPTLSPDSSSQEALSAPTCSPTSDSENLSPDELELLAKLEEQNRLLEADSKSMRSMNGSRRNSGSSLVSSSSASSNLSHLEEDTWILWGRIANEWEEWRRRKEKLLKELIRKGIPHHFRAIVWQLLCSATDMPVKNQYSELLKMSSPCEKLIRRDIARTYPEHEFFKGQDSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVGLLLMQMPEEEAFCVFVRLMQEYRLRELFKPSMAELGLCIYQFEYMLQEQLPDLNTHFRSQSFHTSMYASSWFLTLFLTTFPLPVATRVFDIFMYEGLEIVFRVGLALLQVNQTELMQLDMEGMSQYFQRVIPHQFDSCPDKLVLKAYQVKYNPKKMKRLEKEYAAMKSKEMEEQIEIKGQVTRAQEAEENYVIKRELAVVRQQCSSTAEDLQKAQSTIRQLQEQQENPRLTEDFVSHLETELEQSRLRETETLGALREMQDKVLDMEKRNSSLPDENNVARLQEELKALKVREGEAVASARELKLQLQELSDTWQAHVSRGGRWKESPRKLVLGELQDELMTMRLREAQALADGREWRQRVVELETQDNIHRNLLNRVEAERAALQEKLQYLAAQNKGLQTQLSESRRKQAEAECKSKEEVMAVRLREADSMAAVAEMRQRIAELEIQREEGRIQGQLNHSDSSQYIRELKDQIEELKTEVRLLKGPPTFEDPLAFDGLSLTRHLDEDSLPSSDEELLGVGVGVGVGAALQDPLYPLSPRDARFFRSLDRPAKDSEGSSDSDADELATPYSNQVLDN", "length": 786, "header": "tr|A0A8I6AHD4-1|A0A0G2K1A4_RAT Computationally mapped isoform of Ecotropic viral integration site 5-like OS=Rattus norvegicus OX=10116 GN=Evi5l PE=4 SV=1 CANONICAL=A0A0G2K1A4-1" }, "locus": { "chromosome": "12", "start_pos": 2557342, "end_pos": 2535072, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000114920.1", "url": "https://www.ensembl.org/id/ENSRNOT00000114920.1" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000092619.1", "url": "https://www.ensembl.org/id/ENSRNOP00000092619.1" } ] } }, { "isoform_ac": "D3ZCJ7-1", "url": "", "sequence": { "sequence": "MSLSTMASPTLSPDSSSQEALSAPTCSPTSDSENLSPDELELLAKLEEQNRLLEADSKSMRSMNGSRRNSGSSLVSSSSASSNLSHLEEDTWILWGRIANEWEEWRRRKEKLLKELIRKGIPHHFRAIVWQLLCSATDMPVKNQYSELLKMSSPCEKLIRRDIARTYPEHEFFKGQDSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVGLLLMQMPEEEAFCVFVRLMQEYRLRELFKPSMAELGLCIYQFEYMLQEQLPDLNTHFRSQSFHTSMYASSWFLTLFLTTFPLPVATRVFDIFMYEGLEIVFRVGLALLQVNQTELMQLDMEGMSQYFQRVIPHQFDSCPDKLVLKAYQVKYNPKKMKRLEKEYAAMKSKEMEEQIEIKPRVGAHSPIGMSSKLASQQ", "length": 406, "header": "tr|D3ZCJ7-1|A0A0G2K1A4_RAT Computationally mapped isoform of Ecotropic viral integration site 5-like OS=Rattus norvegicus OX=10116 GN=Evi5l PE=4 SV=4 CANONICAL=A0A0G2K1A4-1" }, "locus": { "chromosome": "12", "start_pos": 2545605, "end_pos": 2535072, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000034124.7", "url": "https://www.ensembl.org/id/ENSRNOT00000034124.7" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000036774.7", "url": "https://www.ensembl.org/id/ENSRNOP00000036774.7" } ] } }, { "isoform_ac": "D3ZXM4-1", "url": "", "sequence": { "sequence": "MSLSTMASPTLSPDSSSQEALSAPTCSPTSDSENLSPDELELLAKLEEQNRLLEADSKSMRSMNGSRRNSGSSLVSSSSASSNLSHLEEDTWILWGRIANEWEEWRRRKEKLLKELIRKGIPHHFRAIVWQLLCSATDMPVKNQYSELLKMSSPCEKLIRRDIARTYPEHEFFKGQDSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVGLLLMQMPEEEAFCVFVRLMQEYRLRELFKPSMAELGLCIYQFEYMLQEQLPDLNTHFRSQSFHTSMYASSWFLTLFLTTFPLPVATRVFDIFMYEGLEIVFRVGLALLQVNQTELMQLDMEGMSQYFQRVIPHQFDSCPDKLVLKAYQVKYNPKKMKRLEKEYAAMKSKEMEEQIEIKRLRTENRLLKQRIETLEKENPRLTEDFVSHLETELEQSRLRETETLGALREMQDKVLDMEKRNSSLPDENNVARLQEELKALKVREGEAVASARELKLQLQELSDTWQAHVSRGGRWKESPRKLVLGELQDELMTMRLREAQALADGREWRQRVVELETQDNIHRNLLNRVEAERAALQEKLQYLAAQNKGLQTQLSESRRKQAEAECKSKEEVMAVRLREADSMAAVAEMRQRIAELEIQREEGRIQGQLNHSDSSQYIRELKDQIEELKTEVRLLKGPPTFEDPLAFDGLSLTRHLDEDSLPSSDEELLGVGVGVGVGAALQDPLYPLSPRDARFFRSLDRPAKDSEGSSDSDADELATPYSNQVLDN", "length": 757, "header": "tr|D3ZXM4-1|A0A0G2K1A4_RAT Computationally mapped isoform of Ecotropic viral integration site 5-like OS=Rattus norvegicus OX=10116 GN=Evi5l PE=4 SV=3 CANONICAL=A0A0G2K1A4-1" }, "locus": { "chromosome": "12", "start_pos": 2557342, "end_pos": 2535072, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000001367.8", "url": "https://www.ensembl.org/id/ENSRNOT00000001367.8" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000001367.7", "url": "https://www.ensembl.org/id/ENSRNOP00000001367.7" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of cilium assembly", "id": "GO:1902018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902018", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K1A4", "url": "https://www.uniprot.org/uniprot/A0A0G2K1A4" } ], "pmid": "" }, { "name": "positive regulation of GTPase activity", "id": "GO:0043547", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043547", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K1A4", "url": "https://www.uniprot.org/uniprot/A0A0G2K1A4" } ], "pmid": "" }, { "name": "activation of GTPase activity", "id": "GO:0090630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090630", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K1A4", "url": "https://www.uniprot.org/uniprot/A0A0G2K1A4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K1A4", "url": "https://www.uniprot.org/uniprot/A0A0G2K1A4" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2K1A4", "url": "https://www.uniprot.org/uniprot/A0A0G2K1A4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 320, "end_pos": 322, "annotation": "n_glycosylation_sequon" }, { "start_pos": 34, "end_pos": 36, "annotation": "n_glycosylation_sequon" }, { "start_pos": 508, "end_pos": 510, "annotation": "n_glycosylation_sequon" }, { "start_pos": 64, "end_pos": 66, "annotation": "n_glycosylation_sequon" }, { "start_pos": 697, "end_pos": 699, "annotation": "n_glycosylation_sequon" }, { "start_pos": 83, "end_pos": 85, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "synthesized_glycans": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }