{
    "uniprot_canonical_ac": "A0A0G2JZM9-1",
    "uniprot_ac": "A0A0G2JZM9",
    "uniprot_id": "A0A0G2JZM9_RAT",
    "mass": {
        "chemical_mass": 22573.0,
        "monoisotopic_mass": 22573.0
    },
    "refseq": {
        "ac": "NP_001128228",
        "name": "glucosamine 6-phosphate N-acetyltransferase",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001128228"
    },
    "gene_names": [
        {
            "name": "Gnpnat1",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A0G2JZM9",
            "id": "A0A0G2JZM9"
        },
        {
            "name": "Gnpnat1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001128228",
            "id": "NP_001128228"
        },
        {
            "name": "RGD1563144",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001128228",
            "id": "NP_001128228"
        }
    ],
    "protein_names": [
        {
            "name": "Glucosamine 6-phosphate N-acetyltransferase",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "A0A0G2JZM9"
        },
        {
            "name": "2.3.1.4",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "A0A0G2JZM9"
        },
        {
            "name": "glucosamine 6-phosphate N-acetyltransferase",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001128228",
            "id": "NP_001128228"
        }
    ],
    "function": [],
    "disease": [
        {
            "disease_id": "DOID:0080753",
            "recommended_name": {
                "id": "DOID:0080753",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0080753",
                "name": "keratosis follicularis spinulosa decalvans",
                "description": "A keratosis pilaris atrophicans that is characterized by scarring alopecia of the scalp, eyebrows, and axillae, sometimes associated with photophobia and keratoderma."
            },
            "synonyms": [],
            "evidence": [
                {
                    "id": "0080753",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080753"
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            ]
        },
        {
            "disease_id": "DOID:162",
            "recommended_name": {
                "id": "DOID:162",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:162",
                "name": "cancer",
                "description": "A disease of cellular proliferation that is malignant and primary, characterized by uncontrolled cellular proliferation, local cell invasion and metastasis."
            },
            "synonyms": [
                {
                    "id": "DOID:162",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:162",
                    "name": "malignant neoplasm",
                    "description": ""
                },
                {
                    "id": "DOID:162",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:162",
                    "name": "malignant tumor",
                    "description": ""
                },
                {
                    "id": "DOID:162",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:162",
                    "name": "primary cancer",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "162",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:162"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A0G2JZM9",
                    "url": "https://www.uniprot.org/uniprot/A0A0G2JZM9"
                }
            ],
            "common_name": "Rat"
        }
    ],
    "gene": [
        {
            "name": "Gnpnat1",
            "url": "https://www.uniprot.org/uniprot/A0A0G2JZM9",
            "locus": {
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                "start_pos": 18596442,
                "end_pos": 18608739,
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                "evidence": [
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                        "database": "Ensembl Gene",
                        "id": "ENSRNOG00000008641",
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                ]
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        }
    ],
    "crossref": [
        {
            "id": "ENSRNOG00000008641",
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000008641",
            "database": "Bgee",
            "categories": [
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        },
        {
            "id": "498486",
            "url": "https://www.ncbi.nlm.nih.gov/gene/498486",
            "database": "GeneID",
            "categories": [
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            ]
        },
        {
            "id": "IPR000182",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000182",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR016181",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR016181",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR039143",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR039143",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "rno:498486",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:498486",
            "database": "KEGG Pathway",
            "categories": [
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            ]
        },
        {
            "id": "NQRYDWI",
            "url": "https://omabrowser.org/oma/group/NQRYDWI/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "1341425at2759",
            "url": "http://www.orthodb.org/?query=1341425at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR13355",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13355",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR13355:SF11",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13355:SF11",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00583",
            "url": "http://pfam.xfam.org/family/PF00583",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "1563144",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1563144",
            "database": "RGD",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "10292",
            "url": "https://www.rhea-db.org/rhea/10292",
            "database": "Rhea",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "A0A0G2JZM9",
            "url": "https://www.uniprot.org/uniprot/A0A0G2JZM9",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A0G2JZM9-1",
            "url": "https://www.uniprot.org/uniprot/A0A0G2JZM9-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I6AKF3",
            "url": "https://www.uniprot.org/uniprot/A0A8I6AKF3",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I6AKF3-1",
            "url": "https://www.uniprot.org/uniprot/A0A8I6AKF3-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A6KDZ8",
            "url": "https://www.uniprot.org/uniprot/A6KDZ8",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A6KDZ8-1",
            "url": "https://www.uniprot.org/uniprot/A6KDZ8-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MKPDETPMFDPSLLKEVDWSQNTAIFSPAISPMHPGEGLVLRPLCTADLNKGFFKVLGQLTETGVVSPEQFMKSFEHMKKSGDYYVTVVEDVTLGQIVATATLIIEHKFIHSCAKSSFLLLQPVSSLTTRLKNAVVCQCSATRGCLWLLGVQMIRKGGDFLTKGIYFQLESFLALYFSTVCLPFLVVKSMGSKQLCHLLSAAHF",
        "length": 204,
        "header": "tr|A0A0G2JZM9-1|A0A0G2JZM9_RAT Isoform 1 of Glucosamine 6-phosphate N-acetyltransferase  OS=Rattus norvegicus OX=10116 GN=Gnpnat1 PE=1 SV=1 CANONICAL=A0A0G2JZM9-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A0G2JZM9-1",
            "url": "",
            "sequence": {
                "sequence": "MKPDETPMFDPSLLKEVDWSQNTAIFSPAISPMHPGEGLVLRPLCTADLNKGFFKVLGQLTETGVVSPEQFMKSFEHMKKSGDYYVTVVEDVTLGQIVATATLIIEHKFIHSCAKSSFLLLQPVSSLTTRLKNAVVCQCSATRGCLWLLGVQMIRKGGDFLTKGIYFQLESFLALYFSTVCLPFLVVKSMGSKQLCHLLSAAHF",
                "length": 204,
                "header": "tr|A0A0G2JZM9-1|A0A0G2JZM9_RAT Isoform 1 of Glucosamine 6-phosphate N-acetyltransferase  OS=Rattus norvegicus OX=10116 GN=Gnpnat1 PE=1 SV=1 CANONICAL=A0A0G2JZM9-1"
            },
            "locus": {
                "chromosome": "15",
                "start_pos": 18604658,
                "end_pos": 18597145,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000078850.2",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000078850.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000071110.2",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000071110.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A8I6AKF3-1",
            "url": "",
            "sequence": {
                "sequence": "MKPDETPMFDPSLLKEVDWSQNTAIFSPAISPMHPGEGLVLRPLCTADLNKGFFKVLGQLTETGVVSPEQFMKSFEHMKKSGDYYVTVVEDVTLGQIVATATLIIEHKFIHSCAKRGRVEDVVVSDELCTCNHGNWKLNCYKITLECLPQNVGFYKKFDYTVSEENYMCRRFLK",
                "length": 174,
                "header": "tr|A0A8I6AKF3-1|A0A0G2JZM9_RAT Computationally mapped isoform of Glucosamine 6-phosphate N-acetyltransferase  OS=Rattus norvegicus OX=10116 GN=Gnpnat1 PE=1 SV=1 CANONICAL=A0A0G2JZM9-1"
            },
            "locus": {
                "chromosome": "15",
                "start_pos": 18604658,
                "end_pos": 18597454,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000115628.1",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000115628.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000093866.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000093866.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A6KDZ8-1",
            "url": "",
            "sequence": {
                "sequence": "MKPDETPMFDPSLLKEVDWSQNTAIFSPAISPMHPGEGLVLRPLCTADLNKGFFKVLGQLTETGVVSPEQFMKSFEHMKKSGDYYVTVVEDVTLGQIVATATLIIEHKFIHSCAKRGRVEDVVVSDECRGKQLGKLLLSTLTLLSKKLNCYKITLECLPQNVGFYKKFDYTVSEENYMCRRFLK",
                "length": 184,
                "header": "tr|A6KDZ8-1|A0A0G2JZM9_RAT Computationally mapped isoform of Glucosamine 6-phosphate N-acetyltransferase  OS=Rattus norvegicus OX=10116 GN=Gnpnat1 PE=1 SV=1 CANONICAL=A0A0G2JZM9-1"
            },
            "locus": {
                "chromosome": "15",
                "start_pos": 18604658,
                "end_pos": 18597454,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000012036.7",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000012036.7"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000012036.3",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000012036.3"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [
        "enzyme"
    ],
    "publication": [],
    "pathway": [
        {
            "id": "rno:498486",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:498486",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q96EK6-1",
            "protein_name": "Glucosamine 6-phosphate N-acetyltransferase",
            "gene_name": "GNPNAT1",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MKPDETPMFDPSLLKEVDWSQNTATFSPAISPTHPGEGLVLRPLCTADLNRGFFKVLGQLTETGVVSPEQFMKSFEHMKKSGDYYVTVVEDVTLGQIVATATLIIEHKFIHSCAKRGRVEDVVVSDECRGKQLGKLLLSTLTLLSKKLNCYKITLECLPQNVGFYKKFGYTVSEENYMCRRFLK",
                "length": 184
            },
            "evidence": [
                {
                    "id": "45233798",
                    "url": "http://www.informatics.jax.org/homology/45233798",
                    "database": "MGI"
                }
            ],
            "common_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q9JK38-1",
            "protein_name": "Glucosamine 6-phosphate N-acetyltransferase",
            "gene_name": "Gnpnat1",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MKPDETPMFDPSLLKEVDWSQNTAIFSPAISPTHPGEGLVLRPLCTADLNKGFFKVLGQLTETGVVSPEQFMKSFEHMKKSGDYYVTVVEDVTLGQIVATATLIIEHKFIHSCAKRGRVEDVVVSDECRGKQLGKLLLSTLTLLSKKLNCYKITLECLPQNVGFYKKFDYTVSEENYMCRRFLK",
                "length": 184
            },
            "evidence": [
                {
                    "id": "45233798",
                    "url": "http://www.informatics.jax.org/homology/45233798",
                    "database": "MGI"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Biological Process",
                "total": 5,
                "go_terms": [
                    {
                        "name": "N-acetylglucosamine metabolic process",
                        "id": "GO:0006044",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006044",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JZM9",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JZM9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "liver development",
                        "id": "GO:0001889",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001889",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JZM9",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JZM9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cellular response to leukemia inhibitory factor",
                        "id": "GO:1990830",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990830",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JZM9",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JZM9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "glucosamine metabolic process",
                        "id": "GO:0006041",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006041",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JZM9",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JZM9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "UDP-N-acetylglucosamine biosynthetic process",
                        "id": "GO:0006048",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006048",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JZM9",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JZM9"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 5,
                "go_terms": [
                    {
                        "name": "endoplasmic reticulum",
                        "id": "GO:0005783",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JZM9",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JZM9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "Golgi apparatus",
                        "id": "GO:0005794",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JZM9",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JZM9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "membrane",
                        "id": "GO:0016020",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JZM9",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JZM9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "late endosome",
                        "id": "GO:0005770",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JZM9",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JZM9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "endoplasmic reticulum-Golgi intermediate compartment",
                        "id": "GO:0005793",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005793",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JZM9",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JZM9"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 3,
                "go_terms": [
                    {
                        "name": "identical protein binding",
                        "id": "GO:0042802",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JZM9",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JZM9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "glucosamine 6-phosphate N-acetyltransferase activity",
                        "id": "GO:0004343",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004343",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JZM9",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JZM9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "monosaccharide binding",
                        "id": "GO:0048029",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048029",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JZM9",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JZM9"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [
        {
            "id": "10292",
            "name": "",
            "equation": "acetyl-CoA + D-glucosamine 6-phosphate = CoA + H(+) + N-acetyl-D-glucosamine 6-phosphate",
            "summary": "",
            "cellular_location": "",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "A0A8I5Y6Y7-1",
                "A0A0G2JZM9-1",
                "Q96EK6-1",
                "Q9JK38-1",
                "P43577-1",
                "Q54WR8-1",
                "Q9VAI0-1"
            ],
            "evidence": [
                {
                    "id": "10292",
                    "database": "Rhea",
                    "url": "https://www.rhea-db.org/rhea/10292"
                }
            ]
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