{ "uniprot_canonical_ac": "A0A0G2JWR6-1", "uniprot_ac": "A0A0G2JWR6", "uniprot_id": "A0A0G2JWR6_RAT", "mass": { "chemical_mass": 54827.0, "monoisotopic_mass": 54827.0 }, "refseq": { "ac": "NP_001101862", "name": "zinc finger protein ZIC 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101862" }, "gene_names": [ { "name": "Zic2", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A0A0G2JWR6", "id": "A0A0G2JWR6" }, { "name": "Zic2", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101862", "id": "NP_001101862" } ], "protein_names": [ { "name": "Zic family member 2", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "A0A0G2JWR6" }, { "name": "zinc finger protein ZIC 2", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101862", "id": "NP_001101862" }, { "name": "zinc finger protein of the cerebellum 2; Zic family member 2 (odd-paired homolog, Drosophila)", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101862", "id": "NP_001101862" } ], "function": [], "disease": [ { "disease_id": "DOID:0110878", "recommended_name": { "id": "DOID:0110878", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0110878", "name": "holoprosencephaly 5", "description": "A holoprosencephaly that has_material_basis_in heterozygous mutation in the ZIC2 gene on chromosome 13q32." }, "synonyms": [ { "id": "DOID:0110878", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0110878", "name": "HPE5", "description": "" }, { "id": "MONDO:0012322", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012322", "name": "holoprosencephaly 5", "description": "Holoprosencephaly associated with mutations in the ZIC2 gene." }, { "id": "MONDO:0012322", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012322", "name": "HPE5", "description": "" }, { "id": "MONDO:0012322", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012322", "name": "ZIC2 holoprosencephaly", "description": "" }, { "id": "MONDO:0012322", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012322", "name": "holoprosencephaly 5", "description": "" }, { "id": "MONDO:0012322", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012322", "name": "holoprosencephaly caused by mutation in ZIC2", "description": "" }, { "id": "MONDO:0012322", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012322", "name": "holoprosencephaly type 5", "description": "" }, { "id": "MIM:609637", "resource": "MIM", "url": "https://www.omim.org/entry/609637", "name": "Holoprosencephaly 5", "description": "Holoprosencephaly 5" } ], "evidence": [ { "id": "0110878", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:0110878" } ] }, { "disease_id": "DOID:4621", "recommended_name": { "id": "DOID:4621", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:4621", "name": "holoprosencephaly", "description": "A congenital nervous system abnormality characterized by failed or incomplete separation of the forebrain early in gestation; it is accompanied by a spectrum of characteristic craniofacial anomalies." }, "synonyms": [ { "id": "DOID:4621", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:4621", "name": "Holoprosencephaly sequence", "description": "" }, { "id": "MONDO:0009349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009349", "name": "holoprosencephaly 1", "description": "The most severe form of holoprosencephaly in which there is a complete absence of midline forebrain division resulting in the presence of fused hemispheres and a single ventricle (alobar holoprosencephaly). It is mapped to chromosome 21q22." }, { "id": "MONDO:0009349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009349", "name": "Hpe, familial", "description": "" }, { "id": "MONDO:0009349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009349", "name": "cyclopia", "description": "" }, { "id": "MONDO:0009349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009349", "name": "HPE1", "description": "" }, { "id": "MONDO:0009349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009349", "name": "holoprosencephaly 1", "description": "" }, { "id": "MONDO:0009349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009349", "name": "holoprosencephaly 1, isolated cases", "description": "" }, { "id": "MONDO:0009349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009349", "name": "holoprosencephaly type 1", "description": "" }, { "id": "MONDO:0009349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009349", "name": "Demyer sequence", "description": "" }, { "id": "MONDO:0009349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009349", "name": "arhinencephaly", "description": "" }, { "id": "MONDO:0009349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009349", "name": "holoprosencephaly, familial Alobar", "description": "" }, { "id": "MONDO:0009349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009349", "name": "isolated arhinencephaly", "description": "" } ], "evidence": [ { "id": "4621", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:4621" } ] }, { "disease_id": "DOID:5419", "recommended_name": { "id": "DOID:5419", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness." }, "synonyms": [ { "id": "DOID:5419", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:5419", "name": "schizophrenia-1", "description": "" }, { "id": "MONDO:0005090", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005090", "name": "schizophrenia", "description": "A major psychotic disorder characterized by abnormalities in the perception or expression of reality. It affects the cognitive and psychomotor functions. Common clinical signs and symptoms include delusions, hallucinations, disorganized thinking, and retreat from reality." }, { "id": "MONDO:0005090", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005090", "name": "schizophrenia 12", "description": "" }, { "id": "MONDO:0005090", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005090", "name": "schizophrenia", "description": "" }, { "id": "MONDO:0005090", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005090", "name": "schizophrenia (disease)", "description": "" }, { "id": "MONDO:0005090", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005090", "name": "schizophrenia-1", "description": "" }, { "id": "MONDO:0005090", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005090", "name": "SCZD", "description": "" }, { "id": "MONDO:0005090", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005090", "name": "schizoaffective disorder", "description": "" }, { "id": "MONDO:0005090", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005090", "name": "schizophrenia with or without an affective disorder", "description": "" }, { "id": "MONDO:0005090", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005090", "name": "schizophrenia, susceptibility to", "description": "" }, { "id": "MIM:181500", "resource": "MIM", "url": "https://www.omim.org/entry/181500", "name": "Schizophrenia", "description": "Schizophrenia" } ], "evidence": [ { "id": "5419", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:5419" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JWR6", "url": "https://www.uniprot.org/uniprot/A0A0G2JWR6" } ], "common_name": "Rat" } ], "gene": [ { "name": "Zic2", "url": "https://www.uniprot.org/uniprot/A0A0G2JWR6", "locus": { "chromosome": "15", "start_pos": 99581522, "end_pos": 99576697, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSRNOG00000054879", "url": "https://www.ensembl.org/id/ENSRNOG00000054879" } ] } } ], "crossref": [ { "id": "ENSRNOG00000054879", "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000054879", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "361096", "url": "https://www.ncbi.nlm.nih.gov/gene/361096", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041643", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041643", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "rno:361096", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:361096", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HGPHSSQ", "url": "https://omabrowser.org/oma/group/HGPHSSQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR19818", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19818", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19818:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19818:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "http://pfam.xfam.org/family/PF00096", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF18366", "url": "http://pfam.xfam.org/family/PF18366", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "NP_001101862", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101862", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "1311174", "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1311174", "database": "RGD", "categories": [ "Organism-specific" ] }, { "id": "A0A0G2JWR6", "url": "https://www.uniprot.org/uniprot/A0A0G2JWR6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0G2JWR6-1", "url": "https://www.uniprot.org/uniprot/A0A0G2JWR6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLDAGPQFPAIGVGSFARHHHHSAAAAAAAAAEMQDRELSLAAAQNGFVDSAAAHMGAFKLNPGAHELSPGQSSAFTSQGPGAYPGSAAAAAAAAALGPHAAHVGSYSGPPFNSTRDFLFRSRGFGDSAPGGGQHGLFGPGAGGLHHAHSDAQGHLLFPGLPEQHGPHASQNVLNGQMRLGLPGEVFGRSEQYRQVASPRTDPYSAAQLHNQYGPMNMNMGMNMAAAAAHHHHHHHHPGAFFRYMRQQCIKQELICKWIDPEQLSNPKKSCNKTFSTMHELVTHVSVEHVGGPEQSNHVCFWEECPREGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFQCEFEGCDRRFANSSDRKKHMHVHTSDKPYLCKMCDKSYTHPSSLRKHMKVHESSPQGSESSPAASSGYESSTPPGLVSPSAEPQSSSNLSPAAAAAAAAAAAAAAAVSAVHRGAGSGSSGSGGGSAAGSGGGGGGAGGGGGGSSGGGSGTAGGHSGLSSNFNEWYV", "length": 529, "header": "tr|A0A0G2JWR6-1|A0A0G2JWR6_RAT Isoform 1 of Zic family member 2 OS=Rattus norvegicus OX=10116 GN=Zic2 PE=3 SV=2 CANONICAL=A0A0G2JWR6-1" }, "isoforms": [ { "isoform_ac": "A0A0G2JWR6-1", "url": "", "sequence": { "sequence": "MLLDAGPQFPAIGVGSFARHHHHSAAAAAAAAAEMQDRELSLAAAQNGFVDSAAAHMGAFKLNPGAHELSPGQSSAFTSQGPGAYPGSAAAAAAAAALGPHAAHVGSYSGPPFNSTRDFLFRSRGFGDSAPGGGQHGLFGPGAGGLHHAHSDAQGHLLFPGLPEQHGPHASQNVLNGQMRLGLPGEVFGRSEQYRQVASPRTDPYSAAQLHNQYGPMNMNMGMNMAAAAAHHHHHHHHPGAFFRYMRQQCIKQELICKWIDPEQLSNPKKSCNKTFSTMHELVTHVSVEHVGGPEQSNHVCFWEECPREGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFQCEFEGCDRRFANSSDRKKHMHVHTSDKPYLCKMCDKSYTHPSSLRKHMKVHESSPQGSESSPAASSGYESSTPPGLVSPSAEPQSSSNLSPAAAAAAAAAAAAAAAVSAVHRGAGSGSSGSGGGSAAGSGGGGGGAGGGGGGSSGGGSGTAGGHSGLSSNFNEWYV", "length": 529, "header": "tr|A0A0G2JWR6-1|A0A0G2JWR6_RAT Isoform 1 of Zic family member 2 OS=Rattus norvegicus OX=10116 GN=Zic2 PE=3 SV=2 CANONICAL=A0A0G2JWR6-1" }, "locus": { "chromosome": "15", "start_pos": 99580447, "end_pos": 99576938, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000089455.2", "url": "https://www.ensembl.org/id/ENSRNOT00000089455.2" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000069986.2", "url": "https://www.ensembl.org/id/ENSRNOP00000069986.2" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "rno:361096", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:361096", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "O95409-1", "protein_name": "Zinc finger protein ZIC 2", "gene_name": "ZIC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLLDAGPQFPAIGVGSFARHHHHSAAAAAAAAAEMQDRELSLAAAQNGFVDSAAAHMGAFKLNPGAHELSPGQSSAFTSQGPGAYPGSAAAAAAAAALGPHAAHVGSYSGPPFNSTRDFLFRSRGFGDSAPGGGQHGLFGPGAGGLHHAHSDAQGHLLFPGLPEQHGPHGSQNVLNGQMRLGLPGEVFGRSEQYRQVASPRTDPYSAAQLHNQYGPMNMNMGMNMAAAAAHHHHHHHHHPGAFFRYMRQQCIKQELICKWIDPEQLSNPKKSCNKTFSTMHELVTHVSVEHVGGPEQSNHVCFWEECPREGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFQCEFEGCDRRFANSSDRKKHMHVHTSDKPYLCKMCDKSYTHPSSLRKHMKVHESSPQGSESSPAASSGYESSTPPGLVSPSAEPQSSSNLSPAAAAAAAAAAAAAAAVSAVHRGGGSGSGGAGGGSGGGSGSGGGGGGAGGGGGGSSGGGSGTAGGHSGLSSNFNEWYV", "length": 532 }, "evidence": [ { "id": "45225250", "url": "http://www.informatics.jax.org/homology/45225250", "database": "MGI" } ], "common_name": "Human" }, { "uniprot_canonical_ac": "Q62520-1", "protein_name": "Zinc finger protein ZIC 2", "gene_name": "Zic2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLDAGPQFPAIGVGSFARHHHHSAAAAAAAAAEMQDRELSLAAAQNGFVDSAAAHMGAFKLNPGAHELSPGQSSAFTSQGPGAYPGSAAAAAAAAALGPHAAHVGSYSGPPFNSTRDFLFRSRGFGDSAPGGGQHGLFGPGAGGLHHAHSDAQGHLLFPGLPPEQHGPHASQNVLNGQMRLGLPGEVFGRSEQYRQVASPRTDPYSAAQLHNQYGPMNMNMGMNMAAAAAHHHHHHHHPGAFFRYMRQQCIKQELICKWIDPEQLSNPKKSCNKTFSTMHELVTHVSVEHVGGPEQSNHVCFWEECPREGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFQCEFEGCDRRFANSSDRKKHMHVHTSDKPYLCKMCDKSYTHPSSLRKHMKVHESSPQGSESSPAASSGYESSTPPGLVSPSAEPQSSSNLSPAAAAAAAAAAAAAAAVSAVHRGAGSGSSGSGGGSAAGSGGGGGGAGGGGGGSSGGGSGTTGGHSGLSSNFNEWYV", "length": 530 }, "evidence": [ { "id": "45225250", "url": "http://www.informatics.jax.org/homology/45225250", "database": "MGI" } ], "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 8, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JWR6", "url": "https://www.uniprot.org/uniprot/A0A0G2JWR6" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JWR6", "url": "https://www.uniprot.org/uniprot/A0A0G2JWR6" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JWR6", "url": "https://www.uniprot.org/uniprot/A0A0G2JWR6" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JWR6", "url": "https://www.uniprot.org/uniprot/A0A0G2JWR6" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JWR6", "url": "https://www.uniprot.org/uniprot/A0A0G2JWR6" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JWR6", "url": "https://www.uniprot.org/uniprot/A0A0G2JWR6" } ], "pmid": "" }, { "name": "chromatin DNA binding", "id": "GO:0031490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031490", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JWR6", "url": "https://www.uniprot.org/uniprot/A0A0G2JWR6" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JWR6", "url": "https://www.uniprot.org/uniprot/A0A0G2JWR6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JWR6", "url": "https://www.uniprot.org/uniprot/A0A0G2JWR6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JWR6", "url": "https://www.uniprot.org/uniprot/A0A0G2JWR6" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JWR6", "url": "https://www.uniprot.org/uniprot/A0A0G2JWR6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 19, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JWR6", "url": "https://www.uniprot.org/uniprot/A0A0G2JWR6" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JWR6", "url": "https://www.uniprot.org/uniprot/A0A0G2JWR6" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JWR6", "url": "https://www.uniprot.org/uniprot/A0A0G2JWR6" } ], "pmid": "" }, { "name": "positive regulation of DNA-binding transcription factor activity", "id": "GO:0051091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051091", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JWR6", "url": "https://www.uniprot.org/uniprot/A0A0G2JWR6" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JWR6", "url": "https://www.uniprot.org/uniprot/A0A0G2JWR6" } ], "pmid": "" }, { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JWR6", "url": "https://www.uniprot.org/uniprot/A0A0G2JWR6" } ], "pmid": "" }, { "name": "visual perception", "id": "GO:0007601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007601", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JWR6", "url": "https://www.uniprot.org/uniprot/A0A0G2JWR6" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JWR6", "url": "https://www.uniprot.org/uniprot/A0A0G2JWR6" } ], "pmid": "" }, { "name": "neural tube closure", "id": "GO:0001843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001843", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JWR6", "url": "https://www.uniprot.org/uniprot/A0A0G2JWR6" } ], "pmid": "" }, { "name": "neural crest cell differentiation", "id": "GO:0014033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014033", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JWR6", "url": "https://www.uniprot.org/uniprot/A0A0G2JWR6" } ], "pmid": "" }, { "name": "developmental pigmentation", "id": "GO:0048066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048066", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JWR6", "url": "https://www.uniprot.org/uniprot/A0A0G2JWR6" } ], "pmid": "" }, { "name": "cilium organization", "id": "GO:0044782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044782", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JWR6", "url": "https://www.uniprot.org/uniprot/A0A0G2JWR6" } ], "pmid": "" }, { "name": "gene expression", "id": "GO:0010467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010467", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JWR6", "url": "https://www.uniprot.org/uniprot/A0A0G2JWR6" } ], "pmid": "" }, { "name": "retinal ganglion cell axon guidance", "id": "GO:0031290", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031290", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JWR6", "url": "https://www.uniprot.org/uniprot/A0A0G2JWR6" } ], "pmid": "" }, { "name": "paraxial mesoderm development", "id": "GO:0048339", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048339", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JWR6", "url": "https://www.uniprot.org/uniprot/A0A0G2JWR6" } ], "pmid": "" }, { "name": "positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry", "id": "GO:1900224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900224", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JWR6", "url": "https://www.uniprot.org/uniprot/A0A0G2JWR6" } ], "pmid": "" }, { "name": "neural plate development", "id": "GO:0001840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001840", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JWR6", "url": "https://www.uniprot.org/uniprot/A0A0G2JWR6" } ], "pmid": "" }, { "name": "axial mesoderm development", "id": "GO:0048318", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048318", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JWR6", "url": "https://www.uniprot.org/uniprot/A0A0G2JWR6" } ], "pmid": "" }, { "name": "central nervous system segmentation", "id": "GO:0035283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035283", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JWR6", "url": "https://www.uniprot.org/uniprot/A0A0G2JWR6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 114, "end_pos": 116, "annotation": "n_glycosylation_sequon" }, { "start_pos": 273, "end_pos": 275, "annotation": "n_glycosylation_sequon" }, { "start_pos": 375, "end_pos": 377, "annotation": "n_glycosylation_sequon" }, { "start_pos": 451, "end_pos": 453, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "synthesized_glycans": [], "cluster_types": [ { "name": "homologset.mgi", "label": "MGI Homologs" } ], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }