{
    "uniprot_canonical_ac": "A0A0G2JT63-1",
    "uniprot_ac": "A0A0G2JT63",
    "uniprot_id": "A0A0G2JT63_RAT",
    "mass": {
        "chemical_mass": 145645.0,
        "monoisotopic_mass": 145645.0
    },
    "refseq": {
        "ac": "NP_001100466",
        "name": "cytoplasmic FMR1 interacting protein 2",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100466"
    },
    "gene_names": [
        {
            "name": "Cyfip2",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A0G2JT63",
            "id": "A0A0G2JT63"
        },
        {
            "name": "Cyfip2",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100466",
            "id": "NP_001100466"
        }
    ],
    "protein_names": [
        {
            "name": "Cytoplasmic FMR1-interacting protein",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "A0A0G2JT63"
        },
        {
            "name": "cytoplasmic FMR1 interacting protein 2",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001100466",
            "id": "NP_001100466"
        }
    ],
    "function": [],
    "disease": [
        {
            "disease_id": "DOID:0060393",
            "recommended_name": {
                "id": "DOID:0060393",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0060393",
                "name": "chromosome 15q11.2 deletion syndrome",
                "description": "A chromosomal deletion syndrome that is characterized by intellectual disbaility, dysmorphic facies, psychiatric illness and autism spectrum disorder, has_material_basis_in autosomal dominant inheritance of partial deletion of the long arm of chromosome 15."
            },
            "synonyms": [
                {
                    "id": "DOID:0060393",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0060393",
                    "name": "15q11.2 microdeletion syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0014294",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0014294",
                    "name": "chromosome 15q11.2 deletion syndrome",
                    "description": "15q11.2 microdeletion syndrome is a rare partial autosomal monosomy with a variable phenotypic expression and reduced penetrance associated with an increased susceptibility to neuropsychiatric or neurodevelopmental disorders including delayed psychomotor development, speech delay, autism spectrum disorder, attention deficit-hyperactivity disorder, obsessive-compulsive disorder, epilepsy or seizures. It may also include mild non-specific dysmorphic features (such as dysplastic ears, broad forehead, hypertelorism), cleft palate, neurological and neuroimaging abnormalities (such as ataxia and muscular hypotonia)."
                },
                {
                    "id": "MONDO:0014294",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0014294",
                    "name": "15q11.2 BP1-BP2 microdeletion syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0014294",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0014294",
                    "name": "15q11.2 microdeletion syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0014294",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0014294",
                    "name": "Del(15)(q11.2)",
                    "description": ""
                },
                {
                    "id": "MONDO:0014294",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0014294",
                    "name": "chromosome 15q11.2 deletion syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0014294",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0014294",
                    "name": "monosomy 15q11.2",
                    "description": ""
                },
                {
                    "id": "MONDO:0014294",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0014294",
                    "name": "15q11.2 microdeletion",
                    "description": ""
                },
                {
                    "id": "MONDO:0014294",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0014294",
                    "name": "chromosome 15q11.2 deletion",
                    "description": ""
                },
                {
                    "id": "MONDO:0014294",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0014294",
                    "name": "chromosome 15q11.2 microdeletion",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "0060393",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060393"
                }
            ]
        },
        {
            "disease_id": "DOID:0080430",
            "recommended_name": {
                "id": "DOID:0080430",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0080430",
                "name": "developmental and epileptic encephalopathy 65",
                "description": "A developmental and epileptic encephalopathy characterized by onset in the first months to years of life of various types of intractable seizures, severe to profound psychomotor developmental delay, and mild facial dysmorphism that has_material_basis_in heterozygous mutation in the CYFIP2 gene on chromosome 5q33."
            },
            "synonyms": [
                {
                    "id": "DOID:0080430",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0080430",
                    "name": "early infantile epileptic encephalopathy 65",
                    "description": ""
                },
                {
                    "id": "DOID:0080430",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0080430",
                    "name": "DEE65",
                    "description": ""
                },
                {
                    "id": "MONDO:0033374",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0033374",
                    "name": "developmental and epileptic encephalopathy, 65",
                    "description": ""
                },
                {
                    "id": "MONDO:0033374",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0033374",
                    "name": "DEE65",
                    "description": ""
                },
                {
                    "id": "MONDO:0033374",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0033374",
                    "name": "EIEE65",
                    "description": ""
                },
                {
                    "id": "MONDO:0033374",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0033374",
                    "name": "developmental and epileptic encephalopathy 65",
                    "description": ""
                },
                {
                    "id": "MONDO:0033374",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0033374",
                    "name": "epileptic encephalopathy, early infantile, 65",
                    "description": ""
                },
                {
                    "id": "MIM:618008",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/618008",
                    "name": "Developmental and epileptic encephalopathy 65",
                    "description": "Developmental and epileptic encephalopathy 65"
                }
            ],
            "evidence": [
                {
                    "id": "0080430",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080430"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A0G2JT63",
                    "url": "https://www.uniprot.org/uniprot/A0A0G2JT63"
                }
            ],
            "common_name": "Rat"
        }
    ],
    "gene": [
        {
            "name": "Cyfip2",
            "url": "https://www.uniprot.org/uniprot/A0A0G2JT63",
            "locus": {
                "chromosome": "10",
                "start_pos": 30621318,
                "end_pos": 30741113,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSRNOG00000006557",
                        "url": "https://www.ensembl.org/id/ENSRNOG00000006557"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSRNOG00000006557",
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000006557",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "303073",
            "url": "https://www.ncbi.nlm.nih.gov/gene/303073",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR008081",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR008081",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR009828",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR009828",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "rno:303073",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:303073",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "DQPNRVE",
            "url": "https://omabrowser.org/oma/group/DQPNRVE/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "446059at2759",
            "url": "http://www.orthodb.org/?query=446059at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR12195",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12195",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR12195:SF3",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12195:SF3",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF05994",
            "url": "http://pfam.xfam.org/family/PF05994",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF07159",
            "url": "http://pfam.xfam.org/family/PF07159",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-RNO-2029482",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-2029482",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-RNO-4420097",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-4420097",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-RNO-5663213",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5663213",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-RNO-9013149",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-9013149",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "1305048",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1305048",
            "database": "RGD",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "A0A0G2JT63",
            "url": "https://www.uniprot.org/uniprot/A0A0G2JT63",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A0G2JT63-1",
            "url": "https://www.uniprot.org/uniprot/A0A0G2JT63-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I6AHL8",
            "url": "https://www.uniprot.org/uniprot/A0A8I6AHL8",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I6AHL8-1",
            "url": "https://www.uniprot.org/uniprot/A0A8I6AHL8-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "D3ZX82",
            "url": "https://www.uniprot.org/uniprot/D3ZX82",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "D3ZX82-1",
            "url": "https://www.uniprot.org/uniprot/D3ZX82-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MTTHVTLEDALSNVDLLEELPLPDQQPCIEPPPSSIMYQANFDTNFEDRNAFVTGIARYIEQATVHSSMNEMLEEGHDYAVMLYTWRSCSRAIPQVKCNEQPNRVEIYEKTVEVLEPEVTKLMKFMYFQRKAIERFCSEVKRLCHAERRKDFVSEAYLLTLGKFINMFAVLDELKNMKCSVKNDHSAYKRAAQFLRKMADPQSIQESQNLSMFLANHNRITQCLHQQLEVIPGYEELLADIVNICVDYYENKMYLTPSEKHMLLKVMGFGLYLMDGNVSNIYKLDAKKRINLSKIDKFFKQLQVVPLFGDMQIELARYIKTSAHYEENKSKWTCTQSSISPQYNICEQMVQIRDDHIRFISELARYSNSEVVTGSGLDSQKSDEEYRELFDLALRGLQLLSKWSAHVMEVYSWKLVHPTDKFCNKDCPGTAEEYERATRYNYTSEEKFAFVEVIAMIKGLQVLMGRMESVFNQAIRNTIYAALQDFAQVTLREPLRQAVRKKKNVLISVLQAIRKTICDWEGGREPPNDPCLRGEKDPKGGFDIKVPRRAVGPSSTQLYMVRTMLESLIADKSGSKKTLRSSLDGPIVLAIEDFHKQSFFFTHLLNISEALQQCCDLSQLWFREFFLELTMGRRIQFPIEMSMPWILTDHILETKEPSMMEYVLYPLDLYNDSAYYALTKFKKQFLYDEIEAEVNLCFDQFVYKLADQIFAYYKAMAGSVLLDKRFRAECKNYGVIIPYPPSNRYETLLKQRHVQLLGRSIDLNRLITQRISAAMYKSLDQAISRFESEDLTSIVELEWLLEINRLTHRLLCKHMTLDSFDAMFREANHNVSAPYGRITLHVFWELNFDFLPNYCYNGSTNRFVRTAIPFTQEPQRDKPANVQPYYLYGSKPLNIAYSHIYSSYRNFVGPPHFKTICRLLGYQGIAVVMEELLKIVKSLLQGTILQYVKTLIEVMPKICRLPRHEYGSPGILEFFHHQLKDIIEYAELKTDVFQSLREVGNAILFCLLIEQALSQEEVCDLLHAAPFQNILPRVYIKEGERLEVRMKRLEAKYAPLHLVPLIERLGTPQQIAIAREGDLLTKERLCCGLSMFEVILTRIRSYLQDPIWRGPPPTNGVMHVDECVEFHRLWSAMQFVYCIPVGTNEFTAEQCFGDGLNWAGCSIVVLLGQQRRFDLFDFCYHLLKVQRQDGKDEIIKNVPLKKMADRIRKYQILNNEVFAILNKYMKSVETDSSTVEHVRCFQPPIHQSLATTC",
        "length": 1253,
        "header": "tr|A0A0G2JT63-1|A0A0G2JT63_RAT Isoform 1 of Cytoplasmic FMR1-interacting protein  OS=Rattus norvegicus OX=10116 GN=Cyfip2 PE=3 SV=2 CANONICAL=A0A0G2JT63-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A0G2JT63-1",
            "url": "",
            "sequence": {
                "sequence": "MTTHVTLEDALSNVDLLEELPLPDQQPCIEPPPSSIMYQANFDTNFEDRNAFVTGIARYIEQATVHSSMNEMLEEGHDYAVMLYTWRSCSRAIPQVKCNEQPNRVEIYEKTVEVLEPEVTKLMKFMYFQRKAIERFCSEVKRLCHAERRKDFVSEAYLLTLGKFINMFAVLDELKNMKCSVKNDHSAYKRAAQFLRKMADPQSIQESQNLSMFLANHNRITQCLHQQLEVIPGYEELLADIVNICVDYYENKMYLTPSEKHMLLKVMGFGLYLMDGNVSNIYKLDAKKRINLSKIDKFFKQLQVVPLFGDMQIELARYIKTSAHYEENKSKWTCTQSSISPQYNICEQMVQIRDDHIRFISELARYSNSEVVTGSGLDSQKSDEEYRELFDLALRGLQLLSKWSAHVMEVYSWKLVHPTDKFCNKDCPGTAEEYERATRYNYTSEEKFAFVEVIAMIKGLQVLMGRMESVFNQAIRNTIYAALQDFAQVTLREPLRQAVRKKKNVLISVLQAIRKTICDWEGGREPPNDPCLRGEKDPKGGFDIKVPRRAVGPSSTQLYMVRTMLESLIADKSGSKKTLRSSLDGPIVLAIEDFHKQSFFFTHLLNISEALQQCCDLSQLWFREFFLELTMGRRIQFPIEMSMPWILTDHILETKEPSMMEYVLYPLDLYNDSAYYALTKFKKQFLYDEIEAEVNLCFDQFVYKLADQIFAYYKAMAGSVLLDKRFRAECKNYGVIIPYPPSNRYETLLKQRHVQLLGRSIDLNRLITQRISAAMYKSLDQAISRFESEDLTSIVELEWLLEINRLTHRLLCKHMTLDSFDAMFREANHNVSAPYGRITLHVFWELNFDFLPNYCYNGSTNRFVRTAIPFTQEPQRDKPANVQPYYLYGSKPLNIAYSHIYSSYRNFVGPPHFKTICRLLGYQGIAVVMEELLKIVKSLLQGTILQYVKTLIEVMPKICRLPRHEYGSPGILEFFHHQLKDIIEYAELKTDVFQSLREVGNAILFCLLIEQALSQEEVCDLLHAAPFQNILPRVYIKEGERLEVRMKRLEAKYAPLHLVPLIERLGTPQQIAIAREGDLLTKERLCCGLSMFEVILTRIRSYLQDPIWRGPPPTNGVMHVDECVEFHRLWSAMQFVYCIPVGTNEFTAEQCFGDGLNWAGCSIVVLLGQQRRFDLFDFCYHLLKVQRQDGKDEIIKNVPLKKMADRIRKYQILNNEVFAILNKYMKSVETDSSTVEHVRCFQPPIHQSLATTC",
                "length": 1253,
                "header": "tr|A0A0G2JT63-1|A0A0G2JT63_RAT Isoform 1 of Cytoplasmic FMR1-interacting protein  OS=Rattus norvegicus OX=10116 GN=Cyfip2 PE=3 SV=2 CANONICAL=A0A0G2JT63-1"
            },
            "locus": {
                "chromosome": "10",
                "start_pos": 30721673,
                "end_pos": 30623810,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000081280.2",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000081280.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000068584.2",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000068584.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A8I6AHL8-1",
            "url": "",
            "sequence": {
                "sequence": "MSLKFSLVVSLPSSPSVWETDAAAMTTHVTLEDALSNVDLLEELPLPDQQPCIEPPPSSIMYQANFDTNFEDRNAFVTGIARYIEQATVHSSMNEMLEEGHDYAVMLYTWRSCSRAIPQVKCNEQPNRVEIYEKTVEVLEPEVTKLMKFMYFQRKAIERFCSEVKRLCHAERRKDFVSEAYLLTLGKFINMFAVLDELKNMKCSVKNDHSAYKRAAQFLRKMADPQSIQESQNLSMFLANHNRITQCLHQQLEVIPGYEELLADIVNICVDYYENKMYLTPSEKHMLLKVMGFGLYLMDGNVSNIYKLDAKKRINLSKIDKFFKQLQVVPLFGDMQIELARYIKTSAHYEENKSKWTCTQSSISPQYNICEQMVQIRDDHIRFISELARYSNSEVVTGSGLDSQKSDEEYRELFDLALRGLQLLSKWSAHVMEVYSWKLVHPTDKFCNKDCPGTAEEYERATRYNYTSEEKFAFVEVIAMIKGLQVLMGRMESVFNQAIRNTIYAALQDFAQVTLREPLRQAVRKKKNVLISVLQAIRKTICDWEGGREPPNDPCLRGEKDPKGGFDIKVPRRAVGPSSTQLYMVRTMLESLIADKSGSKKTLRSSLDGPIVLAIEDFHKQSFFFTHLLNISEALQQCCDLSQLWFREFFLELTMGRRIQFPIEMSMPWILTDHILETKEPSMMEYVLYPLDLYNDSAYYALTKFKKQFLYDEIEAEVNLCFDQFVYKLADQIFAYYKAMAGSVLLDKRFRAECKNYGVIIPYPPSNRYETLLKQRHVQLLGRSIDLNRLITQRISAAMYKSLDQAISRFESEDLTSIVELEWLLEINRLTHRLLCKHMTLDSFDAMFREANHNVSAPYGRITLHVFWELNFDFLPNYCYNGSTNRFVRTAIPFTQEPQRDKPANVQPYYLYGSKPLNIAYSHIYSSYRNFVGPPHFKTICRLLGYQGIAVVMEELLKIVKSLLQGTILQYVKTLIEVMPKICRLPRHEYGSPGILEFFHHQLKDIIEYAELKTDVFQSLREVGNAILFCLLIEQALSQEEVCDLLHAAPFQNILPRVYIKEGERLEVRMKRLEAKYAPLHLVPLIERLGTPQQIAIAREGDLLTKERLCCGLSMFEVILTRIRSYLQDPIWRGPPPTNGVMHVDECVEFHRLWSAMQFVYCIPVGTNEFTAEQCFGDGLNWAGCSIVVLLGQQRRFDLFDFCYHLLKVQRQDGKDEIIKNVPLKKMADRIRKYQILNNEVFAILNKYMKSVETDSSTVEHVRCFQPPIHQSLATTC",
                "length": 1277,
                "header": "tr|A0A8I6AHL8-1|A0A8I6AHL8_RAT Computationally mapped isoform of Cytoplasmic FMR1-interacting protein  OS=Rattus norvegicus OX=10116 GN=Cyfip2 PE=3 SV=1 CANONICAL=A0A0G2JT63-1"
            },
            "locus": {
                "chromosome": "10",
                "start_pos": 30721745,
                "end_pos": 30623810,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000119958.1",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000119958.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000094378.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000094378.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "D3ZX82-1",
            "url": "",
            "sequence": {
                "sequence": "MSSTPWICTTTAPTMRSPSSKSSSCMTRSKQRQVNLCFDQFVYKLADQIFAYYKAMAGSVLLDKRFRAECKNYGVIIPYPPSNRYETLLKQRHVQLLGRSIDLNRLITQRISAAMYKSLDQAISRFESEDLTSIVELEWLLEINRLTHRLLCKHMTLDSFDAMFREANHNVSAPYGRITLHVFWELNFDFLPNYCYNGSTNRFVRTAIPFTQEPQRDKPANVQPYYLYGSKPLNIAYSHIYSSYRNFVGPPHFKTICRLLGYQGIAVVMEELLKIVKSLLQGTILQYVKTLIEVMPKICRLPRHEYGSPGILEFFHHQLKDIIEYAELKTDVFQSLREVGNAILFCLLIEQALSQEEVCDLLHAAPFQNILPRVYIKEGERLEVRMKRLEAKYAPLHLVPLIERLGTPQQIAIAREGDLLTKERLCCGLSMFEVILTRIRSYLQDPIWRGPPPTNGVMHVDECVEFHRLWSAMQFVYCIPVGTNEFTAEQCFGDGLNWAGCSIVVLLGQQRRFDLFDFCYHLLKVQRQDGKDEIIKNVPLKKMADRIRKYQILNNEVFAILNKYMKSVETDSSTVEHVRCFQPPIHQSLATTC",
                "length": 593,
                "header": "tr|D3ZX82-1|D3ZX82_RAT Computationally mapped isoform of Cytoplasmic FMR1 interacting protein 2  OS=Rattus norvegicus OX=10116 GN=Cyfip2 PE=4 SV=2 CANONICAL=A0A0G2JT63-1"
            },
            "locus": {
                "chromosome": "10",
                "start_pos": 30683412,
                "end_pos": 30623810,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000059496.5",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000059496.5"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000056255.3",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000056255.3"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [
        {
            "id": "rno:303073",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:303073",
            "resource": "KEGG Pathway"
        },
        {
            "id": "R-RNO-2029482",
            "name": "Regulation of actin dynamics for phagocytic cup formation",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-2029482",
            "resource": "Reactome",
            "description": "Regulation of actin dynamics for phagocytic cup formation"
        },
        {
            "id": "R-RNO-4420097",
            "name": "VEGFA-VEGFR2 Pathway",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-4420097",
            "resource": "Reactome",
            "description": "VEGFA-VEGFR2 Pathway"
        },
        {
            "id": "R-RNO-5663213",
            "name": "RHO GTPases Activate WASPs and WAVEs",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5663213",
            "resource": "Reactome",
            "description": "RHO GTPases Activate WASPs and WAVEs"
        },
        {
            "id": "R-RNO-9013149",
            "name": "RAC1 GTPase cycle",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-9013149",
            "resource": "Reactome",
            "description": "RAC1 GTPase cycle"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q5SQX6-1",
            "protein_name": "Cytoplasmic FMR1-interacting protein 2",
            "gene_name": "Cyfip2",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MTTHVTLEDALSNVDLLEELPLPDQQPCIEPPPSSIMYQANFDTNFEDRNAFVTGIARYIEQATVHSSMNEMLEEGHDYAVMLYTWRSCSRAIPQVKCNEQPNRVEIYEKTVEVLEPEVTKLMKFMYFQRKAIERFCSEVKRLCHAERRKDFVSEAYLLTLGKFINMFAVLDELKNMKCSVKNDHSAYKRAAQFLRKMADPQSIQESQNLSMFLANHNRITQCLHQQLEVIPGYEELLADIVNICVDYYENKMYLTPSEKHMLLKVMGFGLYLMDGNVSNIYKLDAKKRINLSKIDKFFKQLQVVPLFGDMQIELARYIKTSAHYEENKSKWTCTQSSISPQYNICEQMVQIRDDHIRFISELARYSNSEVVTGSGLDSQKSDEEYRELFDLALRGLQLLSKWSAHVMEVYSWKLVHPTDKFCNKDCPGTAEEYERATRYNYTSEEKFAFVEVIAMIKGLQVLMGRMESVFNQAIRNTIYAALQDFAQVTLREPLRQAVRKKKNVLISVLQAIRKTICDWEGGREPPNDPCLRGEKDPKGGFDIKVPRRAVGPSSTQLYMVRTMLESLIADKSGSKKTLRSSLDGPIVLAIEDFHKQSFFFTHLLNISEALQQCCDLSQLWFREFFLELTMGRRIQFPIEMSMPWILTDHILETKEPSMMEYVLYPLDLYNDSAYYALTKFKKQFLYDEIEAEVNLCFDQFVYKLADQIFAYYKAMAGSVLLDKRFRAECKNYGVIIPYPPSNRYETLLKQRHVQLLGRSIDLNRLITQRISAAMYKSLDQAISRFESEDLTSIVELEWLLEINRLTHRLLCKHMTLDSFDAMFREANHNVSAPYGRITLHVFWELNFDFLPNYCYNGSTNRFVRTAIPFTQEPQRDKPANVQPYYLYGSKPLNIAYSHIYSSYRNFVGPPHFKTICRLLGYQGIAVVMEELLKIVKSLLQGTILQYVKTLIEVMPKICRLPRHEYGSPGILEFFHHQLKDIIEYAELKTDVFQSLREVGNAILFCLLIEQALSQEEVCDLLHAAPFQNILPRVYIKEGERLEVRMKRLEAKYAPLHLVPLIERLGTPQQIAIAREGDLLTKERLCCGLSMFEVILTRIRSYLQDPIWRGPPPTNGVMHVDECVEFHRLWSAMQFVYCIPVGTNEFTAEQCFGDGLNWAGCSIIVLLGQQRRFDLFDFCYHLLKVQRQDGKDEIIKNVPLKKMADRIRKYQILNNEVFAILNKYMKSVETDSSTVEHVRCFQPPIHQSLATTC",
                "length": 1253
            },
            "evidence": [
                {
                    "id": "45237456",
                    "url": "http://www.informatics.jax.org/homology/45237456",
                    "database": "MGI"
                }
            ],
            "common_name": "Mouse"
        },
        {
            "uniprot_canonical_ac": "Q96F07-1",
            "protein_name": "Cytoplasmic FMR1-interacting protein 2",
            "gene_name": "CYFIP2",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MTTHVTLEDALSNVDLLEELPLPDQQPCIEPPPSSIMYQANFDTNFEDRNAFVTGIARYIEQATVHSSMNEMLEEGHEYAVMLYTWRSCSRAIPQVKCNEQPNRVEIYEKTVEVLEPEVTKLMKFMYFQRKAIERFCSEVKRLCHAERRKDFVSEAYLLTLGKFINMFAVLDELKNMKCSVKNDHSAYKRAAQFLRKMADPQSIQESQNLSMFLANHNRITQCLHQQLEVIPGYEELLADIVNICVDYYENKMYLTPSEKHMLLKVMGFGLYLMDGNVSNIYKLDAKKRINLSKIDKFFKQLQVVPLFGDMQIELARYIKTSAHYEENKSKWTCTQSSISPQYNICEQMVQIRDDHIRFISELARYSNSEVVTGSGLDSQKSDEEYRELFDLALRGLQLLSKWSAHVMEVYSWKLVHPTDKFCNKDCPGTAEEYERATRYNYTSEEKFAFVEVIAMIKGLQVLMGRMESVFNQAIRNTIYAALQDFAQVTLREPLRQAVRKKKNVLISVLQAIRKTICDWEGGREPPNDPCLRGEKDPKGGFDIKVPRRAVGPSSTQACQWSPRALFHPTGGTQGRRGCRSLLYMVRTMLESLIADKSGSKKTLRSSLDGPIVLAIEDFHKQSFFFTHLLNISEALQQCCDLSQLWFREFFLELTMGRRIQFPIEMSMPWILTDHILETKEPSMMEYVLYPLDLYNDSAYYALTKFKKQFLYDEIEAEVNLCFDQFVYKLADQIFAYYKAMAGSVLLDKRFRAECKNYGVIIPYPPSNRYETLLKQRHVQLLGRSIDLNRLITQRISAAMYKSLDQAISRFESEDLTSIVELEWLLEINRLTHRLLCKHMTLDSFDAMFREANHNVSAPYGRITLHVFWELNFDFLPNYCYNGSTNRFVRTAIPFTQEPQRDKPANVQPYYLYGSKPLNIAYSHIYSSYRNFVGPPHFKTICRLLGYQGIAVVMEELLKIVKSLLQGTILQYVKTLIEVMPKICRLPRHEYGSPGILEFFHHQLKDIIEYAELKTDVFQSLREVGNAILFCLLIEQALSQEEVCDLLHAAPFQNILPRVYIKEGERLEVRMKRLEAKYAPLHLVPLIERLGTPQQIAIAREGDLLTKERLCCGLSMFEVILTRIRSYLQDPIWRGPPPTNGVMHVDECVEFHRLWSAMQFVYCIPVGTNEFTAEQCFGDGLNWAGCSIIVLLGQQRRFDLFDFCYHLLKVQRQDGKDEIIKNVPLKKMADRIRKYQILNNEVFAILNKYMKSVETDSSTVEHVRCFQPPIHQSLATTC",
                "length": 1278
            },
            "evidence": [
                {
                    "id": "45237456",
                    "url": "http://www.informatics.jax.org/homology/45237456",
                    "database": "MGI"
                }
            ],
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Cellular Component",
                "total": 5,
                "go_terms": [
                    {
                        "name": "cytoplasm",
                        "id": "GO:0005737",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JT63",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JT63"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "synapse",
                        "id": "GO:0045202",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JT63",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JT63"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "perinuclear region of cytoplasm",
                        "id": "GO:0048471",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JT63",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JT63"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "SCAR complex",
                        "id": "GO:0031209",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031209",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JT63",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JT63"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "neuron projection",
                        "id": "GO:0043005",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JT63",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JT63"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 11,
                "go_terms": [
                    {
                        "name": "neuron projection development",
                        "id": "GO:0031175",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JT63",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JT63"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "apoptotic process",
                        "id": "GO:0006915",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JT63",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JT63"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cell morphogenesis",
                        "id": "GO:0000902",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000902",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JT63",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JT63"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cell-cell adhesion",
                        "id": "GO:0098609",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JT63",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JT63"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of neurotrophin TRK receptor signaling pathway",
                        "id": "GO:0051388",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051388",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JT63",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JT63"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of proteolysis",
                        "id": "GO:0045862",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045862",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JT63",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JT63"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "axon guidance",
                        "id": "GO:0007411",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JT63",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JT63"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "activation of cysteine-type endopeptidase activity",
                        "id": "GO:0097202",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097202",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JT63",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JT63"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "dendrite extension",
                        "id": "GO:0097484",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097484",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JT63",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JT63"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "regulation of actin filament polymerization",
                        "id": "GO:0030833",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030833",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JT63",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JT63"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cell projection assembly",
                        "id": "GO:0030031",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030031",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JT63",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JT63"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 1,
                "go_terms": [
                    {
                        "name": "small GTPase binding",
                        "id": "GO:0031267",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2JT63",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2JT63"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 209,
            "end_pos": 211,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 277,
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            "annotation": "n_glycosylation_sequon"
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        },
        {
            "start_pos": 328,
            "end_pos": 330,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 441,
            "end_pos": 443,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 606,
            "end_pos": 608,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 671,
            "end_pos": 673,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 830,
            "end_pos": 832,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 857,
            "end_pos": 859,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        },
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        }
    ],
    "section_stats": [
        {
            "table_id": "glycosylation",
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                {
                    "field": "total_sites",
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        {
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            ],
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        {
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        {
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    ]
}