{
    "uniprot_canonical_ac": "A0A0B7P9G0-1",
    "uniprot_ac": "A0A0B7P9G0",
    "uniprot_id": "UEX_DROME",
    "mass": {
        "chemical_mass": 93283.0,
        "monoisotopic_mass": 93283.0
    },
    "refseq": {
        "ac": "NP_001104390",
        "name": "unextended, isoform F",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001104390"
    },
    "gene_names": [
        {
            "name": "uex",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A0B7P9G0",
            "id": "A0A0B7P9G0"
        },
        {
            "name": "41Ad; CG40084; CG42595; CR41594; Dmel\\CG42595; EMS45-73; GroupIII; IR3; l(2)41Ad; l(2)EMS34-7; l(2)IR3; l(2R)A'; l(2R)EMS45-73; l(2Rh)IR3",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001104390",
            "id": "NP_001104390"
        },
        {
            "name": "41Ad",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0B7P9G0",
            "id": "A0A0B7P9G0"
        },
        {
            "name": "CG42595",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0B7P9G0",
            "id": "A0A0B7P9G0"
        },
        {
            "name": "GroupIII",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0B7P9G0",
            "id": "A0A0B7P9G0"
        },
        {
            "name": "l(2)41Ad",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0B7P9G0",
            "id": "A0A0B7P9G0"
        },
        {
            "name": "uex",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001104390",
            "id": "NP_001104390"
        }
    ],
    "protein_names": [
        {
            "name": "Unextended protein",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "A0A0B7P9G0"
        },
        {
            "name": "CG42595-PF; uex-PF; lethal (2) IR3",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001104390",
            "id": "NP_001104390"
        },
        {
            "name": "Putative metal transporter uex",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "A0A0B7P9G0"
        },
        {
            "name": "unextended, isoform F",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001104390",
            "id": "NP_001104390"
        }
    ],
    "function": [
        {
            "annotation": "Probable metal transporter (By similarity). Acts downstream of PRL-1 and protects the nervous system against olfactory carbon dioxide stimulation (PubMed:31404830).",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A0B7P9G0",
                    "url": "https://www.uniprot.org/uniprot/A0A0B7P9G0#function"
                },
                {
                    "database": "PubMed",
                    "id": "31404830",
                    "url": "https://glygen.org/publication/PubMed/31404830"
                },
                {
                    "database": "UniProtKB",
                    "id": "Q3TWN3",
                    "url": "https://www.uniprot.org/uniprot/Q3TWN3#function"
                }
            ]
        }
    ],
    "disease": [
        {
            "disease_id": "DOID:0060884",
            "recommended_name": {
                "id": "DOID:0060884",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0060884",
                "name": "renal hypomagnesemia 6",
                "description": "A hypomagnesemia characterized by autosomal dominant inheritance of severely lowered serum magnesium levels without other electrolyte disturbances or abnormalities in urinary magnesium excretion that has_material_basis_in heterozygous mutation in the CNNM2 gene on chromosome 10q24."
            },
            "synonyms": [
                {
                    "id": "DOID:0060884",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0060884",
                    "name": "HOMG6",
                    "description": ""
                },
                {
                    "id": "MONDO:0013480",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013480",
                    "name": "renal hypomagnesemia 6",
                    "description": ""
                },
                {
                    "id": "MONDO:0013480",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013480",
                    "name": "HOMG6",
                    "description": ""
                },
                {
                    "id": "MONDO:0013480",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013480",
                    "name": "renal hypomagnesemia type 6",
                    "description": ""
                },
                {
                    "id": "MONDO:0013480",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013480",
                    "name": "hypomagnesemia 6, renal",
                    "description": ""
                },
                {
                    "id": "MONDO:0013480",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013480",
                    "name": "renal hypomagnesemia-6",
                    "description": ""
                },
                {
                    "id": "MIM:613882",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/613882",
                    "name": "Hypomagnesemia 6",
                    "description": "Hypomagnesemia 6"
                }
            ],
            "evidence": [
                {
                    "id": "0060884",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060884"
                }
            ]
        },
        {
            "disease_id": "DOID:0111404",
            "recommended_name": {
                "id": "DOID:0111404",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0111404",
                "name": "Jalili syndrome",
                "description": "A syndrome characterized by amelogenesis imperfecta and cone-rod retinal dystrophy that has_material_basis_in homozygous or compound heterozygous mutation in CNNM4 on chromosome 2q11.2."
            },
            "synonyms": [
                {
                    "id": "DOID:0111404",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0111404",
                    "name": "Cone rod dystrophy-amelogenesis imperfecta syndrome",
                    "description": ""
                },
                {
                    "id": "DOID:0111404",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0111404",
                    "name": "cone-rod dystrophy and amelogenesis imperfecta",
                    "description": ""
                },
                {
                    "id": "MONDO:0009007",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009007",
                    "name": "Jalili syndrome",
                    "description": "Jalili syndrome is characterized by the association of amelogenesis imperfecta (AI) and cone-rod retinal dystrophy (CORD)."
                },
                {
                    "id": "MONDO:0009007",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009007",
                    "name": "Jalili syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0009007",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009007",
                    "name": "cone rod dystrophy-amelogenesis imperfecta syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0009007",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009007",
                    "name": "cone-rod dystrophy amelogenesis imperfecta",
                    "description": ""
                },
                {
                    "id": "MONDO:0009007",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009007",
                    "name": "cone-rod dystrophy and amelogenesis imperfecta",
                    "description": ""
                },
                {
                    "id": "MONDO:0009007",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0009007",
                    "name": "cone-rod dystrophy with amelogenesis imperfecta",
                    "description": ""
                },
                {
                    "id": "MIM:217080",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/217080",
                    "name": "Jalili syndrome",
                    "description": "Jalili syndrome"
                }
            ],
            "evidence": [
                {
                    "id": "0111404",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0111404"
                }
            ]
        },
        {
            "disease_id": "DOID:5419",
            "recommended_name": {
                "id": "DOID:5419",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:5419",
                "name": "schizophrenia",
                "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness."
            },
            "synonyms": [
                {
                    "id": "DOID:5419",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:5419",
                    "name": "schizophrenia-1",
                    "description": ""
                },
                {
                    "id": "MONDO:0005090",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0005090",
                    "name": "schizophrenia",
                    "description": "A major psychotic disorder characterized by abnormalities in the perception or expression of reality. It affects the cognitive and psychomotor functions. Common clinical signs and symptoms include delusions, hallucinations, disorganized thinking, and retreat from reality."
                },
                {
                    "id": "MONDO:0005090",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0005090",
                    "name": "schizophrenia 12",
                    "description": ""
                },
                {
                    "id": "MONDO:0005090",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0005090",
                    "name": "schizophrenia",
                    "description": ""
                },
                {
                    "id": "MONDO:0005090",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0005090",
                    "name": "schizophrenia (disease)",
                    "description": ""
                },
                {
                    "id": "MONDO:0005090",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0005090",
                    "name": "schizophrenia-1",
                    "description": ""
                },
                {
                    "id": "MONDO:0005090",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0005090",
                    "name": "SCZD",
                    "description": ""
                },
                {
                    "id": "MONDO:0005090",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0005090",
                    "name": "schizoaffective disorder",
                    "description": ""
                },
                {
                    "id": "MONDO:0005090",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0005090",
                    "name": "schizophrenia with or without an affective disorder",
                    "description": ""
                },
                {
                    "id": "MONDO:0005090",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0005090",
                    "name": "schizophrenia, susceptibility to",
                    "description": ""
                },
                {
                    "id": "MIM:181500",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/181500",
                    "name": "Schizophrenia",
                    "description": "Schizophrenia"
                }
            ],
            "evidence": [
                {
                    "id": "5419",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:5419"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Drosophila melanogaster",
            "taxid": 7227,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A0B7P9G0",
                    "url": "https://www.uniprot.org/uniprot/A0A0B7P9G0"
                }
            ],
            "common_name": "Fruit fly"
        }
    ],
    "gene": [
        {
            "name": "uex",
            "url": "https://www.uniprot.org/uniprot/A0A0B7P9G0",
            "locus": {
                "chromosome": "2R",
                "start_pos": 3900285,
                "end_pos": 3949425,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "FBgn0262124",
                        "url": "https://www.ensembl.org/id/FBgn0262124"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "FBgn0262124",
            "url": "https://bgee.org/?page=gene&gene_id=FBgn0262124",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "cd04590",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04590",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "FBgn0262124",
            "url": "https://flybase.org/reports/FBgn0262124",
            "database": "FlyBase",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "5740320",
            "url": "https://www.ncbi.nlm.nih.gov/gene/5740320",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR000595",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000595",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR000644",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000644",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR002550",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR002550",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR014710",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR014710",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR018490",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR018490",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR044751",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR044751",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR045095",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR045095",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR046342",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR046342",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "dme:Dmel_CG42595",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+dme:Dmel_CG42595",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "RTNIVTM",
            "url": "https://omabrowser.org/oma/group/RTNIVTM/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "248389at2759",
            "url": "http://www.orthodb.org/?query=248389at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR12064",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12064",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR12064:SF94",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12064:SF94",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "8CT8",
            "url": "https://www.rcsb.org/structure/8CT8",
            "database": "PDB",
            "categories": [
                "3D Structure"
            ]
        },
        {
            "id": "PF01595",
            "url": "http://pfam.xfam.org/family/PF01595",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_A0A0B7P9G0",
            "url": "http://purl.obolibrary.org/obo/PR_A0A0B7P9G0",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "NP_001104390",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001104390",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A0B7P9G0",
            "url": "https://www.uniprot.org/uniprot/A0A0B7P9G0",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A0B7P9G0-1",
            "url": "https://www.uniprot.org/uniprot/A0A0B7P9G0-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MNTYFISFITIIIFANGINGTSVDTSNKLLLQKANDFNLSQNLSSSRTRRTIANSFRIVGIRLEDETVETKNGIPTVLVDKEQQFRVFGSGLEENTAITFTNEKNDYGGPCLKPATDLFTPIEVSSNGFSALYSVKFPSFINEFFICAKTAEKTTNHSKAATTTPLEHQGNSDFLKIKTFEPLIPVWLAIIIIVTCLGFSALFSGLNLGLMSMDRTELKILRNTGTEKEKKYASKIAPVRDQGNYLLCSILLGNVLVNSTFTILLDGLTSGLFAVIFSTLAIVLFGEITPQAVCSRHGLAIGAKTILVTKTVMAITAPLSYPVSRILDKLLGEEIGNVYNRERLKELVRVTNDVNDLDKNEVNIISGALELRKKTVADVMTHINDAFMLSLDALLDFETVSEIMNSGYSRIPVYDGDRKNIVTLLYIKDLAFVDTDDNTPLKTLCEFYQNPVHFVFEDYTLDIMFNQFKEGTIGHIAFVHRVNNEGDGDPFYETVGLVTLEDVIEELIQAEIVDETDVFVDNRTKTRRNRYKKADFSAFAERREVQTVRISPQLTLATFQYLSTAVDAFKKDVISELILRRLLNQDVFHNIKTKGKSKDDPSLYIFTQGKAVDFFVLILEGRVEVTIGKEALMFESGPFTYFGTQALVPNVVIDSPTQMGSLQSLNMDSKIRQSFVPDYSVRAISDVIYITIKRVLYLTAKKATLLEKSRKSGTFSSETFDDEVERLLHSITENEKPSCFAQNQSTRRLSNRSINSSPTNMNRSPDFVYNSVDEAIQDDTKLKNIKHADNVTTSISLVAAELEDLHSGEQDTTAASMPLLPKLDDKFESKQSKP",
        "length": 834,
        "header": "sp|A0A0B7P9G0-1|UEX_DROME Isoform 1 of Unextended protein  OS=Drosophila melanogaster OX=7227 GN=uex PE=1 SV=1 CANONICAL=A0A0B7P9G0-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A0B7P9G0-1",
            "url": "",
            "sequence": {
                "sequence": "MNTYFISFITIIIFANGINGTSVDTSNKLLLQKANDFNLSQNLSSSRTRRTIANSFRIVGIRLEDETVETKNGIPTVLVDKEQQFRVFGSGLEENTAITFTNEKNDYGGPCLKPATDLFTPIEVSSNGFSALYSVKFPSFINEFFICAKTAEKTTNHSKAATTTPLEHQGNSDFLKIKTFEPLIPVWLAIIIIVTCLGFSALFSGLNLGLMSMDRTELKILRNTGTEKEKKYASKIAPVRDQGNYLLCSILLGNVLVNSTFTILLDGLTSGLFAVIFSTLAIVLFGEITPQAVCSRHGLAIGAKTILVTKTVMAITAPLSYPVSRILDKLLGEEIGNVYNRERLKELVRVTNDVNDLDKNEVNIISGALELRKKTVADVMTHINDAFMLSLDALLDFETVSEIMNSGYSRIPVYDGDRKNIVTLLYIKDLAFVDTDDNTPLKTLCEFYQNPVHFVFEDYTLDIMFNQFKEGTIGHIAFVHRVNNEGDGDPFYETVGLVTLEDVIEELIQAEIVDETDVFVDNRTKTRRNRYKKADFSAFAERREVQTVRISPQLTLATFQYLSTAVDAFKKDVISELILRRLLNQDVFHNIKTKGKSKDDPSLYIFTQGKAVDFFVLILEGRVEVTIGKEALMFESGPFTYFGTQALVPNVVIDSPTQMGSLQSLNMDSKIRQSFVPDYSVRAISDVIYITIKRVLYLTAKKATLLEKSRKSGTFSSETFDDEVERLLHSITENEKPSCFAQNQSTRRLSNRSINSSPTNMNRSPDFVYNSVDEAIQDDTKLKNIKHADNVTTSISLVAAELEDLHSGEQDTTAASMPLLPKLDDKFESKQSKP",
                "length": 834,
                "header": "sp|A0A0B7P9G0-1|UEX_DROME Isoform 1 of Unextended protein  OS=Drosophila melanogaster OX=7227 GN=uex PE=1 SV=1 CANONICAL=A0A0B7P9G0-1"
            },
            "locus": {
                "chromosome": "2R",
                "start_pos": 3943067,
                "end_pos": 3900789,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "FBtr0346683",
                        "url": "https://www.ensembl.org/id/FBtr0346683"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "FBpp0312292",
                        "url": "https://www.ensembl.org/id/FBpp0312292"
                    }
                ]
            }
        }
    ],
    "glycosylation": [
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "reported",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 156,
            "start_aa": "Asn",
            "end_pos": 156,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn156",
            "evidence": [
                {
                    "id": "A0A0B7P9G0",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/A0A0B7P9G0#ptm_processing"
                },
                {
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