{
    "uniprot_canonical_ac": "A0A0B4LID7-1",
    "uniprot_ac": "A0A0B4LID7",
    "uniprot_id": "A0A0B4LID7_DROME",
    "mass": {
        "chemical_mass": 71652.0,
        "monoisotopic_mass": 71652.0
    },
    "refseq": {
        "ac": "NP_650843",
        "name": "caseinolytic protease chaperone subunit, isoform A",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_650843"
    },
    "gene_names": [
        {
            "name": "ClpX",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A0B4LID7",
            "id": "A0A0B4LID7"
        },
        {
            "name": "CG4538-RA",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0B4LID7",
            "id": "A0A0B4LID7"
        },
        {
            "name": "CG4538; Dmel\\CG4538",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_650843",
            "id": "NP_650843"
        },
        {
            "name": "CG4538",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0B4LID7",
            "id": "A0A0B4LID7"
        },
        {
            "name": "ClpX",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_650843",
            "id": "NP_650843"
        },
        {
            "name": "Dmel\\CG4538",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0B4LID7",
            "id": "A0A0B4LID7"
        },
        {
            "name": "Dmel_CG4538",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0B4LID7",
            "id": "A0A0B4LID7"
        }
    ],
    "protein_names": [
        {
            "name": "3.4.21.-",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "A0A0B4LID7"
        },
        {
            "name": "CG4538-PA; ClpX-PA",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_650843",
            "id": "NP_650843"
        },
        {
            "name": "CG4538-PC; ClpX-PC",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287413",
            "id": "NP_001287413"
        },
        {
            "name": "Uncharacterized protein, isoform C",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "A0A0B4LID7"
        },
        {
            "name": "caseinolytic protease chaperone subunit, isoform A",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_650843",
            "id": "NP_650843"
        },
        {
            "name": "caseinolytic protease chaperone subunit, isoform C",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287413",
            "id": "NP_001287413"
        }
    ],
    "function": [],
    "disease": [
        {
            "disease_id": "DOID:13270",
            "recommended_name": {
                "id": "DOID:13270",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:13270",
                "name": "erythropoietic protoporphyria",
                "description": "An acute porphyria characterized by a deficiency in the enzyme ferrochelatase, leading to abnormally high levels of protoporphyrin in the tissue."
            },
            "synonyms": [
                {
                    "id": "DOID:13270",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:13270",
                    "name": "EPP",
                    "description": ""
                },
                {
                    "id": "DOID:13270",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:13270",
                    "name": "Protoporphyria",
                    "description": ""
                },
                {
                    "id": "MONDO:0008319",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008319",
                    "name": "protoporphyria, erythropoietic, 1",
                    "description": "Erythropoietic protoporphyria caused by a compound heterozygous or homozygous mutation in the gene encoding ferrochelatase (FECH) on chromosome 18q21."
                },
                {
                    "id": "MONDO:0008319",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008319",
                    "name": "erythropoietic protoporphyria",
                    "description": ""
                },
                {
                    "id": "MONDO:0008319",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008319",
                    "name": "protoporphyria, erythropoietic",
                    "description": ""
                },
                {
                    "id": "MONDO:0008319",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008319",
                    "name": "EPP1",
                    "description": ""
                },
                {
                    "id": "MONDO:0008319",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008319",
                    "name": "ferrochelatase deficiency",
                    "description": ""
                },
                {
                    "id": "MONDO:0008319",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008319",
                    "name": "heme synthetase deficiency",
                    "description": ""
                },
                {
                    "id": "MONDO:0008319",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008319",
                    "name": "protoporphyria, erythropoietic, 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0008319",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008319",
                    "name": "EPP",
                    "description": ""
                },
                {
                    "id": "MONDO:0008319",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0008319",
                    "name": "erythrohepatic protoporphyria",
                    "description": ""
                },
                {
                    "id": "MONDO:0010420",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010420",
                    "name": "X-linked erythropoietic protoporphyria",
                    "description": "X-linked form of erythropoietic protoporphyria."
                },
                {
                    "id": "MONDO:0010420",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010420",
                    "name": "X-linked dominant erythropoietic protoporphyria",
                    "description": ""
                },
                {
                    "id": "MONDO:0010420",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010420",
                    "name": "X-linked dominant protoporphyria",
                    "description": ""
                },
                {
                    "id": "MONDO:0010420",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010420",
                    "name": "XLDPP",
                    "description": ""
                },
                {
                    "id": "MONDO:0010420",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010420",
                    "name": "XLP",
                    "description": ""
                },
                {
                    "id": "MONDO:0010420",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010420",
                    "name": "XLPP",
                    "description": ""
                },
                {
                    "id": "MONDO:0010420",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010420",
                    "name": "erythropoietic protoporphyria, X-linked",
                    "description": ""
                },
                {
                    "id": "MONDO:0010420",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010420",
                    "name": "Erythrohepatic protoporphyria, X-linked",
                    "description": ""
                },
                {
                    "id": "MONDO:0010420",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010420",
                    "name": "XLEPP",
                    "description": ""
                },
                {
                    "id": "MONDO:0010420",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010420",
                    "name": "protoporphyria, erythropoietic, X-linked",
                    "description": ""
                },
                {
                    "id": "MONDO:0010420",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010420",
                    "name": "protoporphyria, erythropoietic, X-linked dominant",
                    "description": ""
                },
                {
                    "id": "MIM:177000",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/177000",
                    "name": "Protoporphyria, erythropoietic, 1",
                    "description": "Protoporphyria, erythropoietic, 1"
                },
                {
                    "id": "MIM:300752",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/300752",
                    "name": "Erythropoietic protoporphyria, X-linked dominant",
                    "description": "Erythropoietic protoporphyria, X-linked dominant"
                }
            ],
            "evidence": [
                {
                    "id": "13270",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:13270"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Drosophila melanogaster",
            "taxid": 7227,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A0B4LID7",
                    "url": "https://www.uniprot.org/uniprot/A0A0B4LID7"
                }
            ],
            "common_name": "Fruit fly"
        }
    ],
    "gene": [
        {
            "name": "ClpX",
            "url": "https://www.uniprot.org/uniprot/A0A0B4LID7",
            "locus": {
                "chromosome": "3R",
                "start_pos": 19897372,
                "end_pos": 19903689,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "FBgn0038745",
                        "url": "https://www.ensembl.org/id/FBgn0038745"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "FBgn0038745",
            "url": "https://bgee.org/?page=gene&gene_id=FBgn0038745",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "cd19497",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19497",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "FBgn0038745",
            "url": "https://flybase.org/reports/FBgn0038745",
            "database": "FlyBase",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "42369",
            "url": "https://www.ncbi.nlm.nih.gov/gene/42369",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "Q9VDS7",
            "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VDS7*",
            "database": "IntAct",
            "categories": [
                "Other"
            ]
        },
        {
            "id": "IPR003593",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR003959",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR003959",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR004487",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR004487",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR010603",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR010603",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR019489",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR019489",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR027417",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "dme:Dmel_CG4538",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+dme:Dmel_CG4538",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "HRSDFTN",
            "url": "https://omabrowser.org/oma/group/HRSDFTN/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "452393at2759",
            "url": "http://www.orthodb.org/?query=452393at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR48102",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48102",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR48102:SF7",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48102:SF7",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF07724",
            "url": "http://pfam.xfam.org/family/PF07724",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF10431",
            "url": "http://pfam.xfam.org/family/PF10431",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "NP_001287413",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001287413",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A0B4LID7",
            "url": "https://www.uniprot.org/uniprot/A0A0B4LID7",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A0B4LID7-1",
            "url": "https://www.uniprot.org/uniprot/A0A0B4LID7-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q9VDS7",
            "url": "https://www.uniprot.org/uniprot/Q9VDS7",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q9VDS7-1",
            "url": "https://www.uniprot.org/uniprot/Q9VDS7-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MSMVRRIILLGPKYSVWAKGSGAGQTHGSARCVILSAGSAENSDCGVRRFHLATRNCARNRLMRLEPAMAIPAYIDVTNAHSRTPEDSSESGSGSEGGASASGGSGAKSPGGAAGSGASSTSGADPPGGGSDKFLSCPKCGSACTQVETFVSSTRFVKCAKCNYFFVVLSEVETKQRTKDEPKNQRKPPPPPQKIMEYLDKHVVGQDFAKKVLAVAVYNHYKRIHHNLPQLQNQGAGASNGAGGGLDGIPRPDLLHITGIGHTLNSSPGNELPPKSPTQMGMGGGMGGPGLGAGLTGASSSNARGGGDNRSGSEILDRQSTDVKLEKSNIIMLGPTGSGKTLIAQTIAKCLDVPFAICDCTTLTQAGYVGEDIESVISKLLQDANYNVERAQTGIVFLDEVDKIGAVPGIHQLRDVGGEGVQQGMLKMLEGTVVNVPERNSPRKLRGETVQVDTTNILFVASGAYTGLDRLIARRLNEKYLGFGMPSTSGSGRRAAQSAASPMDNDQEERDKCLTKVQARDLVEFGMIPEFVGRFPVIVPFHSLNVSMLVRILTEPRNALVPQYKALLGLDEVDLTFTEDAVKSIAQLAMERHTGARGLRSIMEQLLLDPMFIVPGSDIRGVHITADYVKGSATPEYSRDADAAASGTVATDSDTTTDNDKNFENSEKSGLNGKLIGAS",
        "length": 679,
        "header": "tr|A0A0B4LID7-1|A0A0B4LID7_DROME Isoform 1 of Uncharacterized protein, isoform C  OS=Drosophila melanogaster OX=7227 GN=ClpX PE=1 SV=1 CANONICAL=A0A0B4LID7-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A0B4LID7-1",
            "url": "",
            "sequence": {
                "sequence": "MSMVRRIILLGPKYSVWAKGSGAGQTHGSARCVILSAGSAENSDCGVRRFHLATRNCARNRLMRLEPAMAIPAYIDVTNAHSRTPEDSSESGSGSEGGASASGGSGAKSPGGAAGSGASSTSGADPPGGGSDKFLSCPKCGSACTQVETFVSSTRFVKCAKCNYFFVVLSEVETKQRTKDEPKNQRKPPPPPQKIMEYLDKHVVGQDFAKKVLAVAVYNHYKRIHHNLPQLQNQGAGASNGAGGGLDGIPRPDLLHITGIGHTLNSSPGNELPPKSPTQMGMGGGMGGPGLGAGLTGASSSNARGGGDNRSGSEILDRQSTDVKLEKSNIIMLGPTGSGKTLIAQTIAKCLDVPFAICDCTTLTQAGYVGEDIESVISKLLQDANYNVERAQTGIVFLDEVDKIGAVPGIHQLRDVGGEGVQQGMLKMLEGTVVNVPERNSPRKLRGETVQVDTTNILFVASGAYTGLDRLIARRLNEKYLGFGMPSTSGSGRRAAQSAASPMDNDQEERDKCLTKVQARDLVEFGMIPEFVGRFPVIVPFHSLNVSMLVRILTEPRNALVPQYKALLGLDEVDLTFTEDAVKSIAQLAMERHTGARGLRSIMEQLLLDPMFIVPGSDIRGVHITADYVKGSATPEYSRDADAAASGTVATDSDTTTDNDKNFENSEKSGLNGKLIGAS",
                "length": 679,
                "header": "tr|A0A0B4LID7-1|A0A0B4LID7_DROME Isoform 1 of Uncharacterized protein, isoform C  OS=Drosophila melanogaster OX=7227 GN=ClpX PE=1 SV=1 CANONICAL=A0A0B4LID7-1"
            },
            "locus": {
                "chromosome": "3R",
                "start_pos": 19902898,
                "end_pos": 19899295,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "FBtr0344261",
                        "url": "https://www.ensembl.org/id/FBtr0344261"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "FBpp0310666",
                        "url": "https://www.ensembl.org/id/FBpp0310666"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q9VDS7-1",
            "url": "",
            "sequence": {
                "sequence": "MSMVRRIILLGPKYSVWAKGSGAGQTHGSARCVILSAGSAENSDCGVRRFHLATRNCARNRLMRLEPAMAIPAYIDVTNAHSRTPEDSSESGSGSEGGASASGGSGAKSPGGAAGSGASSTSGADPPGGGSDKFLSCPKCGSACTQVETFVSSTRFVKCAKCNYFFVVLSEVETKQRTKDEPKNQRKPPPPPQKIMEYLDKHVVGQDFAKKVLAVAVYNHYKRIHHNLPQLQNQGAGASNGAGGGLDGIPRPDLLHITGIGHTLNSSPGNELPPKSPTQMGMGGGMGGPGLGAGLTGASSSNARGGGDNRSGSEILDRQSTDVKLEKSNIIMLGPTGSGKTLIAQTIAKCLDVPFAICDCTTLTQAGYVGEDIESVISKLLQDANYNVERAQTGIVFLDEVDKIGAVPGIHQLRDVGGEGVQQGMLKMLEGTVVNVPERNSPRKLRGETVQVDTTNILFVASGAYTGLDRLIARRLNEKYLGFGMPSTSGSGRRAAQSAASPMDNDQEERDKCLTKVQARDLVEFGMIPEFVGRFPVIVPFHSLNVSMLVRILTEPRNALVPQYKALLGLDEVDLTFTEDAVKSIAQLAMERHTGARGLRSIMEQLLLDPMFIVPGSDIRGVHITADYVKGSATPEYSRDADAAASGTVATDSDTTTDNDKNFENSEKVRLKQ",
                "length": 673,
                "header": "tr|Q9VDS7-1|A0A0B4LID7_DROME Computationally mapped isoform of Uncharacterized protein, isoform C  OS=Drosophila melanogaster OX=7227 GN=ClpX PE=1 SV=2 CANONICAL=A0A0B4LID7-1"
            },
            "locus": {
                "chromosome": "3R",
                "start_pos": 19902898,
                "end_pos": 19899599,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "FBtr0344262",
                        "url": "https://www.ensembl.org/id/FBtr0344262"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "FBpp0310667",
                        "url": "https://www.ensembl.org/id/FBpp0310667"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [
        "enzyme"
    ],
    "publication": [],
    "pathway": [
        {
            "id": "dme:Dmel_CG4538",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+dme:Dmel_CG4538",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [],
    "go_annotation": {
        "categories": [
            {
                "name": "Molecular Function",
                "total": 6,
                "go_terms": [
                    {
                        "name": "ATP binding",
                        "id": "GO:0005524",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0B4LID7",
                                "url": "https://www.uniprot.org/uniprot/A0A0B4LID7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "zinc ion binding",
                        "id": "GO:0008270",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0B4LID7",
                                "url": "https://www.uniprot.org/uniprot/A0A0B4LID7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "protein dimerization activity",
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