{
    "uniprot_canonical_ac": "A0A0B4KH64-1",
    "uniprot_ac": "A0A0B4KH64",
    "uniprot_id": "A0A0B4KH64_DROME",
    "mass": {
        "chemical_mass": 88642.0,
        "monoisotopic_mass": 88642.0
    },
    "refseq": {
        "ac": "NP_733229",
        "name": "barentsz, isoform B",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_733229"
    },
    "gene_names": [
        {
            "name": "btz",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KH64",
            "id": "A0A0B4KH64"
        },
        {
            "name": "Btz; CG12878; Dmel\\CG12878; wkl",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001263027",
            "id": "NP_001263027"
        },
        {
            "name": "Btz",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KH64",
            "id": "A0A0B4KH64"
        },
        {
            "name": "CG12878",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KH64",
            "id": "A0A0B4KH64"
        },
        {
            "name": "Dmel\\CG12878",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KH64",
            "id": "A0A0B4KH64"
        },
        {
            "name": "Dmel_CG12878",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KH64",
            "id": "A0A0B4KH64"
        },
        {
            "name": "btz-RA",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KH64",
            "id": "A0A0B4KH64"
        },
        {
            "name": "btz",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001263027",
            "id": "NP_001263027"
        },
        {
            "name": "wkl",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KH64",
            "id": "A0A0B4KH64"
        }
    ],
    "protein_names": [
        {
            "name": "Protein CASC3",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "A0A0B4KH64"
        },
        {
            "name": "CG12878-PB; btz-PB; Dm SELOR; weak localizer; barentsz; barentz",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_733229",
            "id": "NP_733229"
        },
        {
            "name": "CG12878-PC; btz-PC; Dm SELOR; weak localizer; barentsz; barentz",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001263027",
            "id": "NP_001263027"
        },
        {
            "name": "CG12878-PD; btz-PD; Dm SELOR; weak localizer; barentsz; barentz",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001263028",
            "id": "NP_001263028"
        },
        {
            "name": "barentsz, isoform B",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_733229",
            "id": "NP_733229"
        },
        {
            "name": "barentsz, isoform C",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001263027",
            "id": "NP_001263027"
        },
        {
            "name": "barentsz, isoform D",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001263028",
            "id": "NP_001263028"
        }
    ],
    "function": [],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Drosophila melanogaster",
            "taxid": 7227,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A0B4KH64",
                    "url": "https://www.uniprot.org/uniprot/A0A0B4KH64"
                }
            ],
            "common_name": "Fruit fly"
        }
    ],
    "gene": [
        {
            "name": "btz",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KH64",
            "locus": {
                "chromosome": "3R",
                "start_pos": 27703445,
                "end_pos": 27700361,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "FBgn0045862",
                        "url": "https://www.ensembl.org/id/FBgn0045862"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "FBgn0045862",
            "url": "https://bgee.org/?page=gene&gene_id=FBgn0045862",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "FBgn0045862",
            "url": "https://flybase.org/reports/FBgn0045862",
            "database": "FlyBase",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "43331",
            "url": "https://www.ncbi.nlm.nih.gov/gene/43331",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "Q9VB04",
            "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9VB04*",
            "database": "IntAct",
            "categories": [
                "Other"
            ]
        },
        {
            "id": "IPR018545",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR018545",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR028544",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR028544",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "dme:Dmel_CG12878",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+dme:Dmel_CG12878",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "NRNYGRV",
            "url": "https://omabrowser.org/oma/group/NRNYGRV/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "5403767at2759",
            "url": "http://www.orthodb.org/?query=5403767at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR13434",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13434",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR13434:SF0",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13434:SF0",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF09405",
            "url": "http://pfam.xfam.org/family/PF09405",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-DME-159236",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-159236",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-DME-72163",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-72163",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-DME-72187",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-72187",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-DME-73856",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-73856",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-DME-975957",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-975957",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "NP_001263028",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001263028",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A0B4KH64",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KH64",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A0B4KH64-1",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KH64-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q7KRX5",
            "url": "https://www.uniprot.org/uniprot/Q7KRX5",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q7KRX5-1",
            "url": "https://www.uniprot.org/uniprot/Q7KRX5-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q9VB04",
            "url": "https://www.uniprot.org/uniprot/Q9VB04",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q9VB04-1",
            "url": "https://www.uniprot.org/uniprot/Q9VB04-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MAEVEKPTAATPPTDIPQATAAPASEAPVAVTPTADTTVDVEPGTSPTQEPNSNSHPHDSEYDTASDLEGGEDYDDEESASGSASGSGSEEESETDDEDDEVGSETDDGEGEQAMDRSVADSEAQKKVDEDRSNPQYIPKRGTFYEHDDRTAETEGEILIEPENGAGQAAAEPNGELNGLAAAGATPTGQTPQISQASKTMRKWQPASGGDRWSHDRFEATEQAPKSRAELLQTYGYDIRNEDAPPRARRRRRYTRGPSKYSRNWEDEQAYLKASNKERKPPRPQDFPALNERKPRGPRTSSSREEKENRRSVAAEGLVPEKQQPLASSSNPHRSQERERERERERERDREPKNRNFGRMNGGPGRQNGMEFKKNNRGQQLRERERGPDQLDNRNQKPSTPRSNQQQQPQQQPHHQQQPQQQRQPSQPQQSPQTPLSTSNLSQRLQQVQQRNDPSHVGSVQMHSLASQNQAPQQQQQQPLHQEQRNAPKRYSSLRRSQQEASQHLAEQQQQQMQQQLHLQQQQQQQQSQIMIQDPHVLMQIAYQQQELQAQLQTMQLGPPTAAGAVPTPPKPHAPPAAAYPQAQAAPYYVTGTEPVPVPVPQAPYVNPASAAYLPTTPAAVAYAQAGPPVVTQPTPPPAQAPPATQPAQPYQNYNTVGGTTYFVPPAQTTSRPSALPQRRPTNAIPILPPSEKHKVKGGAKEEGISDNIDHIIDNMFVQRPSAFQATGEGATPGGGTKEEAAATPPAAEQNLQPVPATGQEXVQAYAGLPPQQQQRRGQRIAPPPSSGYSMLQPHAGYYRPPPPPH",
        "length": 806,
        "header": "tr|A0A0B4KH64-1|A0A0B4KH64_DROME Isoform 1 of Protein CASC3  OS=Drosophila melanogaster OX=7227 GN=btz PE=1 SV=1 CANONICAL=A0A0B4KH64-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A0B4KH64-1",
            "url": "",
            "sequence": {
                "sequence": "MAEVEKPTAATPPTDIPQATAAPASEAPVAVTPTADTTVDVEPGTSPTQEPNSNSHPHDSEYDTASDLEGGEDYDDEESASGSASGSGSEEESETDDEDDEVGSETDDGEGEQAMDRSVADSEAQKKVDEDRSNPQYIPKRGTFYEHDDRTAETEGEILIEPENGAGQAAAEPNGELNGLAAAGATPTGQTPQISQASKTMRKWQPASGGDRWSHDRFEATEQAPKSRAELLQTYGYDIRNEDAPPRARRRRRYTRGPSKYSRNWEDEQAYLKASNKERKPPRPQDFPALNERKPRGPRTSSSREEKENRRSVAAEGLVPEKQQPLASSSNPHRSQERERERERERERDREPKNRNFGRMNGGPGRQNGMEFKKNNRGQQLRERERGPDQLDNRNQKPSTPRSNQQQQPQQQPHHQQQPQQQRQPSQPQQSPQTPLSTSNLSQRLQQVQQRNDPSHVGSVQMHSLASQNQAPQQQQQQPLHQEQRNAPKRYSSLRRSQQEASQHLAEQQQQQMQQQLHLQQQQQQQQSQIMIQDPHVLMQIAYQQQELQAQLQTMQLGPPTAAGAVPTPPKPHAPPAAAYPQAQAAPYYVTGTEPVPVPVPQAPYVNPASAAYLPTTPAAVAYAQAGPPVVTQPTPPPAQAPPATQPAQPYQNYNTVGGTTYFVPPAQTTSRPSALPQRRPTNAIPILPPSEKHKVKGGAKEEGISDNIDHIIDNMFVQRPSAFQATGEGATPGGGTKEEAAATPPAAEQNLQPVPATGQEXVQAYAGLPPQQQQRRGQRIAPPPSSGYSMLQPHAGYYRPPPPPH",
                "length": 806,
                "header": "tr|A0A0B4KH64-1|A0A0B4KH64_DROME Isoform 1 of Protein CASC3  OS=Drosophila melanogaster OX=7227 GN=btz PE=1 SV=1 CANONICAL=A0A0B4KH64-1"
            },
            "locus": {
                "chromosome": "3R",
                "start_pos": 27703065,
                "end_pos": 27700648,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "FBtr0330085",
                        "url": "https://www.ensembl.org/id/FBtr0330085"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "FBpp0303118",
                        "url": "https://www.ensembl.org/id/FBpp0303118"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q7KRX5-1",
            "url": "",
            "sequence": {
                "sequence": "MSFRRRSSSSSSEAENRRDPAMAEVEKPTAATPPTDIPQATAAPASEAPVAVTPTADTTVDVEPGTSPTQEPNSNSHPHDSEYDTASDLEGGEDYDDEESASGSASGSGSEEESETDDEDDEVGSETDDGEGEQAMDRSVADSEAQKKVDEDRSNPQYIPKRGTFYEHDDRTAETEGEILIEPENGAGQAAAEPNGELNGLAAAGATPTGQTPQISQASKTMRKWQPASGGDRWSHDRFEATEQAPKSRAELLQTYGYDIRNEDAPPRARRRRRYTRGPSKYSRNWEDEQAYLKASNKERKPPRPQDFPALNERKPRGPRTSSSREEKENRRSVAAEGLVPEKQQPLASSSNPHRSQERERERERERERDREPKNRNFGRMNGGPGRQNGMEFKKNNRGQQLRERERGPDQLDNRNQKPSTPRSNQQQQPQQQPHHQQQPQQQRQPSQPQQSPQTPLSTSNLSQRLQQVQQRNDPSHVGSVQMHSLASQNQAPQQQQQQPLHQEQRNAPKRYSSLRRSQQEASQHLAEQQQQQMQQQLHLQQQQQQQQSQIMIQDPHVLMQIAYQQQELQAQLQTMQLGPPTAAGAVPTPPKPHAPPAAAYPQAQAAPYYVTGTEPVPVPVPQAPYVNPASAAYLPTTPAAVAYAQAGPPVVTQPTPPPAQAPPATQPAQPYQNYNTVGGTTYFVPPAQTTSRPSALPQRRPTNAIPILPPSEKHKVKGGAKEEGISDNIDHIIDNMFVQRPSAFQATGEGATPGGGTKEEAAATPPAAEQNLQPVPATGQE",
                "length": 782,
                "header": "tr|Q7KRX5-1|Q7KRX5_DROME Computationally mapped isoform of Protein CASC3  OS=Drosophila melanogaster OX=7227 GN=btz PE=1 SV=1 CANONICAL=A0A0B4KH64-1"
            },
            "locus": {
                "chromosome": "3R",
                "start_pos": 27702930,
                "end_pos": 27700585,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "FBtr0085221",
                        "url": "https://www.ensembl.org/id/FBtr0085221"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "FBpp0084591",
                        "url": "https://www.ensembl.org/id/FBpp0084591"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q9VB04-1",
            "url": "",
            "sequence": {
                "sequence": "MAEVEKPTAATPPTDIPQATAAPASEAPVAVTPTADTTVDVEPGTSPTQEPNSNSHPHDSEYDTASDLEGGEDYDDEESASGSASGSGSEEESETDDEDDEVGSETDDGEGEQAMDRSVADSEAQKKVDEDRSNPQYIPKRGTFYEHDDRTAETEGEILIEPENGAGQAAAEPNGELNGLAAAGATPTGQTPQISQASKTMRKWQPASGGDRWSHDRFEATEQAPKSRAELLQTYGYDIRNEDAPPRARRRRRYTRGPSKYSRNWEDEQAYLKASNKERKPPRPQDFPALNERKPRGPRTSSSREEKENRRSVAAEGLVPEKQQPLASSSNPHRSQERERERERERERDREPKNRNFGRMNGGPGRQNGMEFKKNNRGQQLRERERGPDQLDNRNQKPSTPRSNQQQQPQQQPHHQQQPQQQRQPSQPQQSPQTPLSTSNLSQRLQQVQQRNDPSHVGSVQMHSLASQNQAPQQQQQQPLHQEQRNAPKRYSSLRRSQQEASQHLAEQQQQQMQQQLHLQQQQQQQQSQIMIQDPHVLMQIAYQQQELQAQLQTMQLGPPTAAGAVPTPPKPHAPPAAAYPQAQAAPYYVTGTEPVPVPVPQAPYVNPASAAYLPTTPAAVAYAQAGPPVVTQPTPPPAQAPPATQPAQPYQNYNTVGGTTYFVPPAQTTSRPSALPQRRPTNAIPILPPSEKHKVKGGAKEEGISDNIDHIIDNMFVQRPSAFQATGEGATPGGGTKEEAAATPPAAEQNLQPVPATGQE",
                "length": 761,
                "header": "tr|Q9VB04-1|A0A0B4KH64_DROME Computationally mapped isoform of Protein CASC3  OS=Drosophila melanogaster OX=7227 GN=btz PE=1 SV=1 CANONICAL=A0A0B4KH64-1"
            },
            "locus": {
                "chromosome": "3R",
                "start_pos": 27702930,
                "end_pos": 27700648,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "FBtr0330084",
                        "url": "https://www.ensembl.org/id/FBtr0330084"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "FBpp0303117",
                        "url": "https://www.ensembl.org/id/FBpp0303117"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [
        {
            "id": "dme:Dmel_CG12878",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+dme:Dmel_CG12878",
            "resource": "KEGG Pathway"
        },
        {
            "id": "R-DME-159236",
            "name": "Transport of Mature mRNA derived from an Intron-Containing Transcript",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-159236",
            "resource": "Reactome",
            "description": "Transport of Mature mRNA derived from an Intron-Containing Transcript"
        },
        {
            "id": "R-DME-72163",
            "name": "mRNA Splicing - Major Pathway",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-72163",
            "resource": "Reactome",
            "description": "mRNA Splicing - Major Pathway"
        },
        {
            "id": "R-DME-72187",
            "name": "mRNA 3'-end processing",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-72187",
            "resource": "Reactome",
            "description": "mRNA 3'-end processing"
        },
        {
            "id": "R-DME-73856",
            "name": "RNA Polymerase II Transcription Termination",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-73856",
            "resource": "Reactome",
            "description": "RNA Polymerase II Transcription Termination"
        },
        {
            "id": "R-DME-975957",
            "name": "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-975957",
            "resource": "Reactome",
            "description": "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
        }
    ],
    "orthologs": [],
    "go_annotation": {
        "categories": [
            {
                "name": "Molecular Function",
                "total": 2,
                "go_terms": [
                    {
                        "name": "mRNA binding",
                        "id": "GO:0003729",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0B4KH64",
                                "url": "https://www.uniprot.org/uniprot/A0A0B4KH64"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "translation initiation factor binding",
                        "id": "GO:0031369",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031369",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0B4KH64",
                                "url": "https://www.uniprot.org/uniprot/A0A0B4KH64"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 8,
                "go_terms": [
                    {
                        "name": "nuclear envelope",
                        "id": "GO:0005635",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0B4KH64",
                                "url": "https://www.uniprot.org/uniprot/A0A0B4KH64"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cytoplasm",
                        "id": "GO:0005737",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0B4KH64",
                                "url": "https://www.uniprot.org/uniprot/A0A0B4KH64"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "nuclear speck",
                        "id": "GO:0016607",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607",
                        "evidence": [
                            {
                                "database": "UniProtKB",
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