{
    "uniprot_canonical_ac": "A0A0B4KFZ1-1",
    "uniprot_ac": "A0A0B4KFZ1",
    "uniprot_id": "A0A0B4KFZ1_DROME",
    "mass": {
        "chemical_mass": 32447.0,
        "monoisotopic_mass": 32447.0
    },
    "refseq": {
        "ac": "NP_611813",
        "name": "entomoglyceroporin 4, isoform A",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611813"
    },
    "gene_names": [
        {
            "name": "Eglp4",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KFZ1",
            "id": "A0A0B4KFZ1"
        },
        {
            "name": "Aqp4019; CG4019; Dmel\\CG4019; Eglp 4",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001246482",
            "id": "NP_001246482"
        },
        {
            "name": "Aqp4019",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KFZ1",
            "id": "A0A0B4KFZ1"
        },
        {
            "name": "CG4019-RC",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KFZ1",
            "id": "A0A0B4KFZ1"
        },
        {
            "name": "CG4019-RD",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KFZ1",
            "id": "A0A0B4KFZ1"
        },
        {
            "name": "CG4019",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KFZ1",
            "id": "A0A0B4KFZ1"
        },
        {
            "name": "Dmel\\CG4019",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KFZ1",
            "id": "A0A0B4KFZ1"
        },
        {
            "name": "Dmel_CG4019",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KFZ1",
            "id": "A0A0B4KFZ1"
        },
        {
            "name": "Eglp 4",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KFZ1",
            "id": "A0A0B4KFZ1"
        },
        {
            "name": "Eglp4",
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            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001246482",
            "id": "NP_001246482"
        }
    ],
    "protein_names": [
        {
            "name": "CG4019-PA; Eglp4-PA",
            "resource": "RefSeq",
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            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611813",
            "id": "NP_611813"
        },
        {
            "name": "CG4019-PC; Eglp4-PC",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_726347",
            "id": "NP_726347"
        },
        {
            "name": "CG4019-PE; Eglp4-PE",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001246482",
            "id": "NP_001246482"
        },
        {
            "name": "CG4019-PF; Eglp4-PF",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261154",
            "id": "NP_001261154"
        },
        {
            "name": "Entomoglyceroporin 4, isoform F",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "A0A0B4KFZ1"
        },
        {
            "name": "entomoglyceroporin 4, isoform A",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611813",
            "id": "NP_611813"
        },
        {
            "name": "entomoglyceroporin 4, isoform C",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_726347",
            "id": "NP_726347"
        },
        {
            "name": "entomoglyceroporin 4, isoform E",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001246482",
            "id": "NP_001246482"
        },
        {
            "name": "entomoglyceroporin 4, isoform F",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261154",
            "id": "NP_001261154"
        }
    ],
    "function": [],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Drosophila melanogaster",
            "taxid": 7227,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A0B4KFZ1",
                    "url": "https://www.uniprot.org/uniprot/A0A0B4KFZ1"
                }
            ],
            "common_name": "Fruit fly"
        }
    ],
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            "name": "Eglp4",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KFZ1",
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                "start_pos": 23607592,
                "end_pos": 23614710,
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                "evidence": [
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                        "database": "Ensembl Gene",
                        "id": "FBgn0034885",
                        "url": "https://www.ensembl.org/id/FBgn0034885"
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                ]
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        }
    ],
    "crossref": [
        {
            "id": "FBgn0034885",
            "url": "https://bgee.org/?page=gene&gene_id=FBgn0034885",
            "database": "Bgee",
            "categories": [
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            ]
        },
        {
            "id": "FBgn0034885",
            "url": "https://flybase.org/reports/FBgn0034885",
            "database": "FlyBase",
            "categories": [
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            ]
        },
        {
            "id": "37739",
            "url": "https://www.ncbi.nlm.nih.gov/gene/37739",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "D1Z394",
            "url": "https://www.ebi.ac.uk/intact/interactors/id:D1Z394*",
            "database": "IntAct",
            "categories": [
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            ]
        },
        {
            "id": "Q6NR72",
            "url": "https://www.ebi.ac.uk/intact/interactors/id:Q6NR72*",
            "database": "IntAct",
            "categories": [
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            ]
        },
        {
            "id": "Q8MLR2",
            "url": "https://www.ebi.ac.uk/intact/interactors/id:Q8MLR2*",
            "database": "IntAct",
            "categories": [
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            ]
        },
        {
            "id": "IPR000425",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000425",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR022357",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR022357",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR023271",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR023271",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR034294",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR034294",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "dme:Dmel_CG4019",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+dme:Dmel_CG4019",
            "database": "KEGG Pathway",
            "categories": [
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        },
        {
            "id": "IAYKAVF",
            "url": "https://omabrowser.org/oma/group/IAYKAVF/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "3236018at2759",
            "url": "http://www.orthodb.org/?query=3236018at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR19139",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19139",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR19139:SF270",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19139:SF270",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00230",
            "url": "http://pfam.xfam.org/family/PF00230",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-DME-1237044",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1237044",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-DME-1247673",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1247673",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-DME-432040",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-432040",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-DME-432047",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-432047",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "NP_001261154",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261154",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A0B4KFZ1",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KFZ1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A0B4KFZ1-1",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KFZ1-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "D1Z394",
            "url": "https://www.uniprot.org/uniprot/D1Z394",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "D1Z394-1",
            "url": "https://www.uniprot.org/uniprot/D1Z394-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q6NR72",
            "url": "https://www.uniprot.org/uniprot/Q6NR72",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q6NR72-1",
            "url": "https://www.uniprot.org/uniprot/Q6NR72-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q8MLR2",
            "url": "https://www.uniprot.org/uniprot/Q8MLR2",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q8MLR2-1",
            "url": "https://www.uniprot.org/uniprot/Q8MLR2-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
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        "sequence": "MIDEVPKQVYLESRKRWTMACDREGSSLFSVALFKRFSDHFSCCKVFKMKGSTLDKISAFLGELIGTGILVFLGCMGCVKTDLFPNNHLQIVLNFGFAVLIAIQCFGCVSGAHLNPAVTVAAYIYEMVTLRMAFAYFAAQMLGAFIGYGLLMVLLPSPTLTVGAGLCVTLPHTSVTTGQALGIEFVITSILVIVCCGVWDPRNSKFHDSVGIRFGLAIACLACAAGPFTGGSMNPARSFAPALWNKHFESNWIYWLAPLSSSAITAYAYKVVFRREVVEAEITSNEKLRQLEDVQLS",
        "length": 297,
        "header": "tr|A0A0B4KFZ1-1|A0A0B4KFZ1_DROME Isoform 1 of Entomoglyceroporin 4, isoform F  OS=Drosophila melanogaster OX=7227 GN=Eglp4 PE=1 SV=1 CANONICAL=A0A0B4KFZ1-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A0B4KFZ1-1",
            "url": "",
            "sequence": {
                "sequence": "MIDEVPKQVYLESRKRWTMACDREGSSLFSVALFKRFSDHFSCCKVFKMKGSTLDKISAFLGELIGTGILVFLGCMGCVKTDLFPNNHLQIVLNFGFAVLIAIQCFGCVSGAHLNPAVTVAAYIYEMVTLRMAFAYFAAQMLGAFIGYGLLMVLLPSPTLTVGAGLCVTLPHTSVTTGQALGIEFVITSILVIVCCGVWDPRNSKFHDSVGIRFGLAIACLACAAGPFTGGSMNPARSFAPALWNKHFESNWIYWLAPLSSSAITAYAYKVVFRREVVEAEITSNEKLRQLEDVQLS",
                "length": 297,
                "header": "tr|A0A0B4KFZ1-1|A0A0B4KFZ1_DROME Isoform 1 of Entomoglyceroporin 4, isoform F  OS=Drosophila melanogaster OX=7227 GN=Eglp4 PE=1 SV=1 CANONICAL=A0A0B4KFZ1-1"
            },
            "locus": {
                "chromosome": "2R",
                "start_pos": 23608806,
                "end_pos": 23607836,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "FBtr0336929",
                        "url": "https://www.ensembl.org/id/FBtr0336929"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "FBpp0307865",
                        "url": "https://www.ensembl.org/id/FBpp0307865"
                    }
                ]
            }
        },
        {
            "isoform_ac": "D1Z394-1",
            "url": "",
            "sequence": {
                "sequence": "MNLEQQGMDPQGVENQQEIVQAAEGEQQLQSCCKVFKMKGSTLDKISAFLGELIGTGILVFLGCMGCVKTDLFPNNHLQIVLNFGFAVLIAIQCFGCVSGAHLNPAVTVAAYIYEMVTLRMAFAYFAAQMLGAFIGYGLLMVLLPSPTLTVGAGLCVTLPHTSVTTGQALGIEFVITSILVIVCCGVWDPRNSKFHDSVGIRFGLAIACLACAAGPFTGGSMNPARSFAPALWNKHFESNWIYWLAPLSSSAITAYAYKVVFRREVVEAEITSNEKLRQLEDVQLS",
                "length": 286,
                "header": "tr|D1Z394-1|A0A0B4KFZ1_DROME Computationally mapped isoform of Entomoglyceroporin 4, isoform F  OS=Drosophila melanogaster OX=7227 GN=Eglp4 PE=1 SV=1 CANONICAL=A0A0B4KFZ1-1"
            },
            "locus": {
                "chromosome": "2R",
                "start_pos": 23609022,
                "end_pos": 23607836,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "FBtr0306384",
                        "url": "https://www.ensembl.org/id/FBtr0306384"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "FBpp0297476",
                        "url": "https://www.ensembl.org/id/FBpp0297476"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q6NR72-1",
            "url": "",
            "sequence": {
                "sequence": "MKGSTLDKISAFLGELIGTGILVFLGCMGCVKTDLFPNNHLQIVLNFGFAVLIAIQCFGCVSGAHLNPAVTVAAYIYEMVTLRMAFAYFAAQMLGAFIGYGLLMVLLPSPTLTVGAGLCVTLPHTSVTTGQALGIEFVITSILVIVCCGVWDPRNSKFHDSVGIRFGLAIACLACAAGPFTGGSMNPARSFAPALWNKHFESNWIYWLAPLSSSAITAYAYKVVFRREVVEAEITSNEKLRQLEDVQLS",
                "length": 249,
                "header": "tr|Q6NR72-1|Q6NR72_DROME Computationally mapped isoform of RH68439p  OS=Drosophila melanogaster OX=7227 GN=Eglp4 PE=1 SV=1 CANONICAL=A0A0B4KFZ1-1"
            },
            "locus": {
                "chromosome": "2R",
                "start_pos": 23608662,
                "end_pos": 23607836,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "FBtr0072103",
                        "url": "https://www.ensembl.org/id/FBtr0072103"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "FBpp0072012",
                        "url": "https://www.ensembl.org/id/FBpp0072012"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q8MLR2-1",
            "url": "",
            "sequence": {
                "sequence": "MSHEIRCCKVFKMKGSTLDKISAFLGELIGTGILVFLGCMGCVKTDLFPNNHLQIVLNFGFAVLIAIQCFGCVSGAHLNPAVTVAAYIYEMVTLRMAFAYFAAQMLGAFIGYGLLMVLLPSPTLTVGAGLCVTLPHTSVTTGQALGIEFVITSILVIVCCGVWDPRNSKFHDSVGIRFGLAIACLACAAGPFTGGSMNPARSFAPALWNKHFESNWIYWLAPLSSSAITAYAYKVVFRREVVEAEITSNEKLRQLEDVQLS",
                "length": 261,
                "header": "tr|Q8MLR2-1|Q8MLR2_DROME Computationally mapped isoform of RE12132p  OS=Drosophila melanogaster OX=7227 GN=Eglp4 PE=1 SV=1 CANONICAL=A0A0B4KFZ1-1"
            },
            "locus": {
                "chromosome": "2R",
                "start_pos": 23609430,
                "end_pos": 23607836,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "FBtr0072105",
                        "url": "https://www.ensembl.org/id/FBtr0072105"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "FBpp0072014",
                        "url": "https://www.ensembl.org/id/FBpp0072014"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [
        {
            "id": "dme:Dmel_CG4019",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+dme:Dmel_CG4019",
            "resource": "KEGG Pathway"
        },
        {
            "id": "R-DME-1237044",
            "name": "Erythrocytes take up carbon dioxide and release oxygen",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1237044",
            "resource": "Reactome",
            "description": "Erythrocytes take up carbon dioxide and release oxygen"
        },
        {
            "id": "R-DME-1247673",
            "name": "Erythrocytes take up oxygen and release carbon dioxide",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1247673",
            "resource": "Reactome",
            "description": "Erythrocytes take up oxygen and release carbon dioxide"
        },
        {
            "id": "R-DME-432040",
            "name": "Vasopressin regulates renal water homeostasis via Aquaporins",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-432040",
            "resource": "Reactome",
            "description": "Vasopressin regulates renal water homeostasis via Aquaporins"
        },
        {
            "id": "R-DME-432047",
            "name": "Passive transport by Aquaporins",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-432047",
            "resource": "Reactome",
            "description": "Passive transport by Aquaporins"
        }
    ],
    "orthologs": [],
    "go_annotation": {
        "categories": [
            {
                "name": "Cellular Component",
                "total": 4,
                "go_terms": [
                    {
                        "name": "plasma membrane",
                        "id": "GO:0005886",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0B4KFZ1",
                                "url": "https://www.uniprot.org/uniprot/A0A0B4KFZ1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "membrane",
                        "id": "GO:0016020",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0B4KFZ1",
                                "url": "https://www.uniprot.org/uniprot/A0A0B4KFZ1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "basolateral plasma membrane",
                        "id": "GO:0016323",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0B4KFZ1",
                                "url": "https://www.uniprot.org/uniprot/A0A0B4KFZ1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "apical plasma membrane",
                        "id": "GO:0016324",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0B4KFZ1",
                                "url": "https://www.uniprot.org/uniprot/A0A0B4KFZ1"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 2,
                "go_terms": [
                    {
                        "name": "transmembrane transport",
                        "id": "GO:0055085",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085",
                        "evidence": [
                            {
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                                "id": "A0A0B4KFZ1",
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