{
    "uniprot_canonical_ac": "A0A0B4KFC4-1",
    "uniprot_ac": "A0A0B4KFC4",
    "uniprot_id": "A0A0B4KFC4_DROME",
    "mass": {
        "chemical_mass": 73129.0,
        "monoisotopic_mass": 73129.0
    },
    "refseq": {
        "ac": "NP_001261084",
        "name": "ribbon, isoform B",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261084"
    },
    "gene_names": [
        {
            "name": "rib",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KFC4",
            "id": "A0A0B4KFC4"
        },
        {
            "name": "CG7230; Dmel\\CG7230; fus1; gene 5; Rib; RIB",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261085",
            "id": "NP_001261085"
        },
        {
            "name": "CG7230",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KFC4",
            "id": "A0A0B4KFC4"
        },
        {
            "name": "Dmel\\CG7230",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KFC4",
            "id": "A0A0B4KFC4"
        },
        {
            "name": "Dmel_CG7230",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KFC4",
            "id": "A0A0B4KFC4"
        },
        {
            "name": "RIB",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KFC4",
            "id": "A0A0B4KFC4"
        },
        {
            "name": "Rib",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KFC4",
            "id": "A0A0B4KFC4"
        },
        {
            "name": "fus1",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KFC4",
            "id": "A0A0B4KFC4"
        },
        {
            "name": "gene 5",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KFC4",
            "id": "A0A0B4KFC4"
        },
        {
            "name": "rib",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261085",
            "id": "NP_001261085"
        }
    ],
    "protein_names": [
        {
            "name": "CG7230-PB; rib-PB; SGP cluster fusion defects 1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261084",
            "id": "NP_001261084"
        },
        {
            "name": "CG7230-PC; rib-PC; SGP cluster fusion defects 1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261085",
            "id": "NP_001261085"
        },
        {
            "name": "Ribbon, isoform C",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "A0A0B4KFC4"
        },
        {
            "name": "ribbon, isoform B",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261084",
            "id": "NP_001261084"
        },
        {
            "name": "ribbon, isoform C",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261085",
            "id": "NP_001261085"
        }
    ],
    "function": [],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Drosophila melanogaster",
            "taxid": 7227,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A0B4KFC4",
                    "url": "https://www.uniprot.org/uniprot/A0A0B4KFC4"
                }
            ],
            "common_name": "Fruit fly"
        }
    ],
    "gene": [
        {
            "name": "rib",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KFC4",
            "locus": {
                "chromosome": "2R",
                "start_pos": 19281396,
                "end_pos": 19270078,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "FBgn0003254",
                        "url": "https://www.ensembl.org/id/FBgn0003254"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "FBgn0003254",
            "url": "https://bgee.org/?page=gene&gene_id=FBgn0003254",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "cd18315",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18315",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "FBgn0003254",
            "url": "https://flybase.org/reports/FBgn0003254",
            "database": "FlyBase",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "44855",
            "url": "https://www.ncbi.nlm.nih.gov/gene/44855",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "A0A0B4KFC4",
            "url": "https://www.ebi.ac.uk/intact/interactors/id:A0A0B4KFC4*",
            "database": "IntAct",
            "categories": [
                "Other"
            ]
        },
        {
            "id": "Q7KF43",
            "url": "https://www.ebi.ac.uk/intact/interactors/id:Q7KF43*",
            "database": "IntAct",
            "categories": [
                "Other"
            ]
        },
        {
            "id": "IPR000210",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR007889",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR007889",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR009057",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR011333",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "dme:Dmel_CG7230",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+dme:Dmel_CG7230",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "EAGQWPL",
            "url": "https://omabrowser.org/oma/group/EAGQWPL/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "2384378at2759",
            "url": "http://www.orthodb.org/?query=2384378at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR23110",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23110",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR23110:SF105",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23110:SF105",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00651",
            "url": "http://pfam.xfam.org/family/PF00651",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF05225",
            "url": "http://pfam.xfam.org/family/PF05225",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "NP_001261085",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261085",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A0B4KFC4",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KFC4",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A0B4KFC4-1",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KFC4-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q7KF43",
            "url": "https://www.uniprot.org/uniprot/Q7KF43",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q7KF43-1",
            "url": "https://www.uniprot.org/uniprot/Q7KF43-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MGGPTAPVASSGEVGQTYCLRWNNHQTNLVQILHALHEVGSYVDCSLVVDDEQFQAHRVVLAANSPYFQHILKDVPQDHCSIILPGVKGFEIAALLQYMYTGETTVTKSQEPEILRTAKELQVKGLYDNLMKFNHASVTPTSSSGAGGAKPQNGSASNHSSSVISTSTHISPSAAISSSCSPPPPPQFGYQPGYSHYPQQQPMSASQIPAGEAPLTPTQATPHSAASGAGEAGGQWPLTPSAAAAMLNSVYESAADMNPLKRKKLSAISSMLLSGNRDTPILRNVLAQANPADSSQPGPMNANGEKTPTHPHQNTQLPAGLGVSGGERNHSFNGSDYGGDKEPLSPYTDRSFEEETGQSGGKKPEWKRYKQYTRADMMCAIQAVREGMSALQASRKYGLPSRTLYDKVRKLNITTGRGTHRTPKRSPPGAESSQGFSYSAAAAAAAHNYGHGHGHHSEVKRDQKVDHVPAHHGMPPTIPPSAAALLDHAFLQQALENRGGDMAGREALHAMALAAAAHAAANRLSSSPAEMDQRSNGHGMRSPSPQGRHYPHEQEAMDLEMEKHEQNIIKRERDQDEREDADDEEDHEQEHVEDLSLARKERPPSPYSPQPTEAGAGVIMHASSASANGKDHVDYPSSPQFVPIGLKRELMEGEDAQARADXLTLTMAWQYATDSLDSLE",
        "length": 680,
        "header": "tr|A0A0B4KFC4-1|A0A0B4KFC4_DROME Isoform 1 of Ribbon, isoform C  OS=Drosophila melanogaster OX=7227 GN=rib PE=1 SV=1 CANONICAL=A0A0B4KFC4-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A0B4KFC4-1",
            "url": "",
            "sequence": {
                "sequence": "MGGPTAPVASSGEVGQTYCLRWNNHQTNLVQILHALHEVGSYVDCSLVVDDEQFQAHRVVLAANSPYFQHILKDVPQDHCSIILPGVKGFEIAALLQYMYTGETTVTKSQEPEILRTAKELQVKGLYDNLMKFNHASVTPTSSSGAGGAKPQNGSASNHSSSVISTSTHISPSAAISSSCSPPPPPQFGYQPGYSHYPQQQPMSASQIPAGEAPLTPTQATPHSAASGAGEAGGQWPLTPSAAAAMLNSVYESAADMNPLKRKKLSAISSMLLSGNRDTPILRNVLAQANPADSSQPGPMNANGEKTPTHPHQNTQLPAGLGVSGGERNHSFNGSDYGGDKEPLSPYTDRSFEEETGQSGGKKPEWKRYKQYTRADMMCAIQAVREGMSALQASRKYGLPSRTLYDKVRKLNITTGRGTHRTPKRSPPGAESSQGFSYSAAAAAAAHNYGHGHGHHSEVKRDQKVDHVPAHHGMPPTIPPSAAALLDHAFLQQALENRGGDMAGREALHAMALAAAAHAAANRLSSSPAEMDQRSNGHGMRSPSPQGRHYPHEQEAMDLEMEKHEQNIIKRERDQDEREDADDEEDHEQEHVEDLSLARKERPPSPYSPQPTEAGAGVIMHASSASANGKDHVDYPSSPQFVPIGLKRELMEGEDAQARADXLTLTMAWQYATDSLDSLE",
                "length": 680,
                "header": "tr|A0A0B4KFC4-1|A0A0B4KFC4_DROME Isoform 1 of Ribbon, isoform C  OS=Drosophila melanogaster OX=7227 GN=rib PE=1 SV=1 CANONICAL=A0A0B4KFC4-1"
            },
            "locus": {
                "chromosome": "2R",
                "start_pos": 19280168,
                "end_pos": 19278129,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "FBtr0330058",
                        "url": "https://www.ensembl.org/id/FBtr0330058"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "FBpp0303091",
                        "url": "https://www.ensembl.org/id/FBpp0303091"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q7KF43-1",
            "url": "",
            "sequence": {
                "sequence": "MGGPTAPVASSGEVGQTYCLRWNNHQTNLVQILHALHEVGSYVDCSLVVDDEQFQAHRVVLAANSPYFQHILKDVPQDHCSIILPGVKGFEIAALLQYMYTGETTVTKSQEPEILRTAKELQVKGLYDNLMKFNHASVTPTSSSGAGGAKPQNGSASNHSSSVISTSTHISPSAAISSSCSPPPPPQFGYQPGYSHYPQQQPMSASQIPAGEAPLTPTQATPHSAASGAGEAGGQWPLTPSAAAAMLNSVYESAADMNPLKRKKLSAISSMLLSGNRDTPILRNVLAQANPADSSQPGPMNANGEKTPTHPHQNTQLPAGLGVSGGERNHSFNGSDYGGDKEPLSPYTDRSFEEETGQSGGKKPEWKRYKQYTRADMMCAIQAVREGMSALQASRKYGLPSRTLYDKVRKLNITTGRGTHRTPKRSPPGAESSQGFSYSAAAAAAAHNYGHGHGHHSEVKRDQKVDHVPAHHGMPPTIPPSAAALLDHAFLQQALENRGGDMAGREALHAMALAAAAHAAANRLSSSPAEMDQRSNGHGMRSPSPQGRHYPHEQEAMDLEMEKHEQNIIKRERDQDEREDADDEEDHEQEHVEDLSLARKERPPSPYSPQPTEAGAGVIMHASSASANGKDHVDYPSSPQFVPIGLKRELMEGEDAQARAD",
                "length": 661,
                "header": "tr|Q7KF43-1|Q7KF43_DROME Computationally mapped isoform of LD16058p  OS=Drosophila melanogaster OX=7227 GN=rib PE=1 SV=1 CANONICAL=A0A0B4KFC4-1"
            },
            "locus": {
                "chromosome": "2R",
                "start_pos": 19280111,
                "end_pos": 19278129,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "FBtr0086512",
                        "url": "https://www.ensembl.org/id/FBtr0086512"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "FBpp0085700",
                        "url": "https://www.ensembl.org/id/FBpp0085700"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [
        {
            "title": "The Drosophila ribbon gene encodes a nuclear BTB domain protein that promotes epithelial migration and morphogenesis.",
            "journal": "Development",
            "date": "2001",
            "authors": "Shim K, Blake K J, Jack J, Krasnow M A",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q7KF43",
                    "url": "https://www.uniprot.org/uniprot/Q7KF43"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "11731471",
                    "url": "https://glygen.org/publication/PubMed/11731471"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "dme:Dmel_CG7230",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+dme:Dmel_CG7230",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [],
    "go_annotation": {
        "categories": [
            {
                "name": "Biological Process",
                "total": 20,
                "go_terms": [
                    {
                        "name": "hindgut morphogenesis",
                        "id": "GO:0007442",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007442",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0B4KFC4",
                                "url": "https://www.uniprot.org/uniprot/A0A0B4KFC4"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "regulation of transcription by RNA polymerase II",
                        "id": "GO:0006357",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0B4KFC4",
                                "url": "https://www.uniprot.org/uniprot/A0A0B4KFC4"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cell migration",
                        "id": "GO:0016477",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0B4KFC4",
                                "url": "https://www.uniprot.org/uniprot/A0A0B4KFC4"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "regulation of DNA-templated transcription",
                        "id": "GO:0006355",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0B4KFC4",
                                "url": "https://www.uniprot.org/uniprot/A0A0B4KFC4"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "membrane organization",
                        "id": "GO:0061024",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061024",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0B4KFC4",
                                "url": "https://www.uniprot.org/uniprot/A0A0B4KFC4"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "central nervous system development",
                        "id": "GO:0007417",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0B4KFC4",
                                "url": "https://www.uniprot.org/uniprot/A0A0B4KFC4"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cytoskeleton organization",
                        "id": "GO:0007010",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007010",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0B4KFC4",
                                "url": "https://www.uniprot.org/uniprot/A0A0B4KFC4"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "regulation of cell shape",
                        "id": "GO:0008360",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008360",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0B4KFC4",
                                "url": "https://www.uniprot.org/uniprot/A0A0B4KFC4"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "protein localization",
                        "id": "GO:0008104",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0B4KFC4",
                                "url": "https://www.uniprot.org/uniprot/A0A0B4KFC4"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "salivary gland development",
                        "id": "GO:0007431",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007431",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0B4KFC4",
                                "url": "https://www.uniprot.org/uniprot/A0A0B4KFC4"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "salivary gland morphogenesis",
                        "id": "GO:0007435",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007435",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0B4KFC4",
                                "url": "https://www.uniprot.org/uniprot/A0A0B4KFC4"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "gonad development",
                        "id": "GO:0008406",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008406",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0B4KFC4",
                                "url": "https://www.uniprot.org/uniprot/A0A0B4KFC4"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "establishment or maintenance of epithelial cell apical/basal polarity",
                        "id": "GO:0045197",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045197",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0B4KFC4",
                                "url": "https://www.uniprot.org/uniprot/A0A0B4KFC4"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "dorsal closure",
                        "id": "GO:0007391",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007391",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0B4KFC4",
                                "url": "https://www.uniprot.org/uniprot/A0A0B4KFC4"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "open tracheal system development",
                        "id": "GO:0007424",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007424",
                        "evidence": [
                            {
                                "database": "UniProtKB",
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                    {
                        "name": "tracheal outgrowth, open tracheal system",
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