{
    "uniprot_canonical_ac": "A0A0B4KEN4-1",
    "uniprot_ac": "A0A0B4KEN4",
    "uniprot_id": "A0A0B4KEN4_DROME",
    "mass": {
        "chemical_mass": 68932.0,
        "monoisotopic_mass": 68932.0
    },
    "refseq": {
        "ac": "NP_477177",
        "name": "Van gogh, isoform A",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_477177"
    },
    "gene_names": [
        {
            "name": "Vang",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KEN4",
            "id": "A0A0B4KEN4"
        },
        {
            "name": "CG8075; Dmel\\CG8075; stb; Stb; stbm; Stbm; stbm/vang; Strabismus; strabismus/Van Gogh; vang; VANG; vang/stbm; Vang/Stbm; Vangl; vangogh/strabismus",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_477177",
            "id": "NP_477177"
        },
        {
            "name": "CG8075",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KEN4",
            "id": "A0A0B4KEN4"
        },
        {
            "name": "Dmel\\CG8075",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KEN4",
            "id": "A0A0B4KEN4"
        },
        {
            "name": "Dmel_CG8075",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KEN4",
            "id": "A0A0B4KEN4"
        },
        {
            "name": "Stbm",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KEN4",
            "id": "A0A0B4KEN4"
        },
        {
            "name": "Stb",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KEN4",
            "id": "A0A0B4KEN4"
        },
        {
            "name": "VANG",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KEN4",
            "id": "A0A0B4KEN4"
        },
        {
            "name": "Van Gogh",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KEN4",
            "id": "A0A0B4KEN4"
        },
        {
            "name": "Vang-RA",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KEN4",
            "id": "A0A0B4KEN4"
        },
        {
            "name": "Vang",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_477177",
            "id": "NP_477177"
        },
        {
            "name": "stbm",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KEN4",
            "id": "A0A0B4KEN4"
        },
        {
            "name": "stb",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KEN4",
            "id": "A0A0B4KEN4"
        },
        {
            "name": "strabismus",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KEN4",
            "id": "A0A0B4KEN4"
        },
        {
            "name": "vang",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KEN4",
            "id": "A0A0B4KEN4"
        }
    ],
    "protein_names": [
        {
            "name": "Vang-like protein",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "A0A0B4KEN4"
        },
        {
            "name": "CG8075-PA; Vang-PA; VanGogh; vang gogh; sltrabismus; Van Gogh/Strabismus; van-gogh; van gogh; Vang-gogh; strabismus",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_477177",
            "id": "NP_477177"
        },
        {
            "name": "CG8075-PB; Vang-PB; VanGogh; vang gogh; sltrabismus; Van Gogh/Strabismus; van-gogh; van gogh; Vang-gogh; strabismus",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260819",
            "id": "NP_001260819"
        },
        {
            "name": "Van gogh, isoform A",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_477177",
            "id": "NP_477177"
        },
        {
            "name": "Van gogh, isoform B",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260819",
            "id": "NP_001260819"
        }
    ],
    "function": [],
    "disease": [
        {
            "disease_id": "DOID:0060340",
            "recommended_name": {
                "id": "DOID:0060340",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0060340",
                "name": "ciliopathy",
                "description": "A syndrome associated with mutations encoding defective proteins, which result in either abnormal function formation or function of cilia."
            },
            "synonyms": [],
            "evidence": [
                {
                    "id": "0060340",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060340"
                }
            ]
        },
        {
            "disease_id": "DOID:0080074",
            "recommended_name": {
                "id": "DOID:0080074",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0080074",
                "name": "neural tube defect",
                "description": "A physical disorder characterized by incomplete closure of the neural tube."
            },
            "synonyms": [
                {
                    "id": "MONDO:0011120",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011120",
                    "name": "neural tube defects, folate-sensitive",
                    "description": ""
                },
                {
                    "id": "MONDO:0011120",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011120",
                    "name": "neural tube defects, folate-sensitive",
                    "description": ""
                },
                {
                    "id": "MONDO:0011120",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011120",
                    "name": "NTD, folate-sensitive",
                    "description": ""
                },
                {
                    "id": "MONDO:0011120",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011120",
                    "name": "NTDFS",
                    "description": ""
                },
                {
                    "id": "MONDO:0011120",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011120",
                    "name": "neural tube defects, folate-sensitive, susceptibility to",
                    "description": ""
                },
                {
                    "id": "MONDO:0011120",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011120",
                    "name": "neural tube defects, susceptibility to",
                    "description": ""
                },
                {
                    "id": "MONDO:0011120",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011120",
                    "name": "spina bifida, folate-sensitive",
                    "description": ""
                },
                {
                    "id": "MONDO:0010525",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010525",
                    "name": "neural tube defects, X-linked",
                    "description": ""
                },
                {
                    "id": "MONDO:0010525",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010525",
                    "name": "neural tube defects, X-linked",
                    "description": ""
                },
                {
                    "id": "MONDO:0010525",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010525",
                    "name": "X-linked anencephaly/spina bifida",
                    "description": ""
                },
                {
                    "id": "MONDO:0010525",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010525",
                    "name": "anencephaly and spina bifida X-linked",
                    "description": ""
                },
                {
                    "id": "MONDO:0010525",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010525",
                    "name": "spina bifida, X-linked",
                    "description": ""
                },
                {
                    "id": "MIM:601634",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/601634",
                    "name": "Neural tube defects, folate-sensitive",
                    "description": "Neural tube defects, folate-sensitive"
                }
            ],
            "evidence": [
                {
                    "id": "0080074",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080074"
                }
            ]
        },
        {
            "disease_id": "DOID:0080700",
            "recommended_name": {
                "id": "DOID:0080700",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0080700",
                "name": "caudal regression syndrome",
                "description": "A physical disorder that is characterized by impairment of the development of the lower half of the body."
            },
            "synonyms": [
                {
                    "id": "DOID:0080700",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0080700",
                    "name": "caudal dysgenesis syndrome",
                    "description": ""
                },
                {
                    "id": "DOID:0080700",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0080700",
                    "name": "caudal dysplasia sequence",
                    "description": ""
                },
                {
                    "id": "DOID:0080700",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0080700",
                    "name": "caudal regression sequence",
                    "description": ""
                },
                {
                    "id": "DOID:0080700",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0080700",
                    "name": "sacral agenesis",
                    "description": ""
                },
                {
                    "id": "DOID:0080700",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0080700",
                    "name": "sacral defect with anterior meningocele",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "0080700",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080700"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Drosophila melanogaster",
            "taxid": 7227,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A0B4KEN4",
                    "url": "https://www.uniprot.org/uniprot/A0A0B4KEN4"
                }
            ],
            "common_name": "Fruit fly"
        }
    ],
    "gene": [
        {
            "name": "Vang",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KEN4",
            "locus": {
                "chromosome": "2R",
                "start_pos": 9106796,
                "end_pos": 9103238,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "FBgn0015838",
                        "url": "https://www.ensembl.org/id/FBgn0015838"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "FBgn0015838",
            "url": "https://bgee.org/?page=gene&gene_id=FBgn0015838",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "FBgn0015838",
            "url": "https://flybase.org/reports/FBgn0015838",
            "database": "FlyBase",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "35922",
            "url": "https://www.ncbi.nlm.nih.gov/gene/35922",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "A1Z7N9",
            "url": "https://www.ebi.ac.uk/intact/interactors/id:A1Z7N9*",
            "database": "IntAct",
            "categories": [
                "Other"
            ]
        },
        {
            "id": "IPR009539",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR009539",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "dme:Dmel_CG8075",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+dme:Dmel_CG8075",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "YSHYSGH",
            "url": "https://omabrowser.org/oma/group/YSHYSGH/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "2910983at2759",
            "url": "http://www.orthodb.org/?query=2910983at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR20886",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20886",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR20886:SF11",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20886:SF11",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF06638",
            "url": "http://pfam.xfam.org/family/PF06638",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-DME-8980692",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-8980692",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-DME-9013148",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9013148",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-DME-9013149",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9013149",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-DME-9013405",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9013405",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-DME-9013406",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9013406",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-DME-9013407",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9013407",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-DME-9013420",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9013420",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-DME-9013423",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9013423",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-DME-9013424",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9013424",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-DME-9035034",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9035034",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "NP_001260819",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260819",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A0B4KEN4",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KEN4",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A0B4KEN4-1",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KEN4-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A1Z7N9",
            "url": "https://www.uniprot.org/uniprot/A1Z7N9",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A1Z7N9-1",
            "url": "https://www.uniprot.org/uniprot/A1Z7N9-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MENESVKSEHSGRSRRSRNHNNNGGGGGGGGGGGGGSVNNGYHRERDRSRHSHRSTHSSKSAKGFQRGDMAPYQTSVNMTGDGSHDGQEVIEVQILPQDENWGENTTAVTGNTSEQSISMEDINNMWHRESDKGFSFACRRYVESSFYFLLGCGAFFSPVAMVVMPYVGFFPSAFDHPEITQTVRTQLLACSEQCKGQLVSLAARLLLLAIGLWAVFMRRTSATMPRIFLYRALVLLLVTICTFAYWLFYIVQVTNGAKIVVETGGDAVDYKSLVGYATNFVDTLLFIHYVAVVLLELRHQQPCYYIKIIRSPDGVSRSYMLGQLSIQRAAVWVLQHYYVDFPIFNPYLERIPISVSKSQRNKISNSFKYYEVDGVSNSQQQSQSRAVLAANARRRDSSHNERFYEEHEYERRVKKRRARLITAAEEAFTHIKRIHNEPAPALPLDPQEAASAVFPSMARALQKYLRVTRQQPRHTFESILKHLAHCLKHDLSPRAFLEPYLTESPVMQSEKERRWVQSWSLICDEIVSRPIGNECTFQLIQNDVSLMVTVHKLPHFNLAEEVVDPKSNKFVLKLNSETSVXHHHNAPPINTPTHSNQTQSSYLHVFV",
        "length": 608,
        "header": "tr|A0A0B4KEN4-1|A0A0B4KEN4_DROME Isoform 1 of Vang-like protein  OS=Drosophila melanogaster OX=7227 GN=Vang PE=3 SV=1 CANONICAL=A0A0B4KEN4-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A0B4KEN4-1",
            "url": "",
            "sequence": {
                "sequence": "MENESVKSEHSGRSRRSRNHNNNGGGGGGGGGGGGGSVNNGYHRERDRSRHSHRSTHSSKSAKGFQRGDMAPYQTSVNMTGDGSHDGQEVIEVQILPQDENWGENTTAVTGNTSEQSISMEDINNMWHRESDKGFSFACRRYVESSFYFLLGCGAFFSPVAMVVMPYVGFFPSAFDHPEITQTVRTQLLACSEQCKGQLVSLAARLLLLAIGLWAVFMRRTSATMPRIFLYRALVLLLVTICTFAYWLFYIVQVTNGAKIVVETGGDAVDYKSLVGYATNFVDTLLFIHYVAVVLLELRHQQPCYYIKIIRSPDGVSRSYMLGQLSIQRAAVWVLQHYYVDFPIFNPYLERIPISVSKSQRNKISNSFKYYEVDGVSNSQQQSQSRAVLAANARRRDSSHNERFYEEHEYERRVKKRRARLITAAEEAFTHIKRIHNEPAPALPLDPQEAASAVFPSMARALQKYLRVTRQQPRHTFESILKHLAHCLKHDLSPRAFLEPYLTESPVMQSEKERRWVQSWSLICDEIVSRPIGNECTFQLIQNDVSLMVTVHKLPHFNLAEEVVDPKSNKFVLKLNSETSVXHHHNAPPINTPTHSNQTQSSYLHVFV",
                "length": 608,
                "header": "tr|A0A0B4KEN4-1|A0A0B4KEN4_DROME Isoform 1 of Vang-like protein  OS=Drosophila melanogaster OX=7227 GN=Vang PE=3 SV=1 CANONICAL=A0A0B4KEN4-1"
            },
            "locus": {
                "chromosome": "2R",
                "start_pos": 9105466,
                "end_pos": 9103576,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "FBtr0330624",
                        "url": "https://www.ensembl.org/id/FBtr0330624"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "FBpp0303474",
                        "url": "https://www.ensembl.org/id/FBpp0303474"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A1Z7N9-1",
            "url": "",
            "sequence": {
                "sequence": "MENESVKSEHSGRSRRSRNHNNNGGGGGGGGGGGGGSVNNGYHRERDRSRHSHRSTHSSKSAKGFQRGDMAPYQTSVNMTGDGSHDGQEVIEVQILPQDENWGENTTAVTGNTSEQSISMEDINNMWHRESDKGFSFACRRYVESSFYFLLGCGAFFSPVAMVVMPYVGFFPSAFDHPEITQTVRTQLLACSEQCKGQLVSLAARLLLLAIGLWAVFMRRTSATMPRIFLYRALVLLLVTICTFAYWLFYIVQVTNGAKIVVETGGDAVDYKSLVGYATNFVDTLLFIHYVAVVLLELRHQQPCYYIKIIRSPDGVSRSYMLGQLSIQRAAVWVLQHYYVDFPIFNPYLERIPISVSKSQRNKISNSFKYYEVDGVSNSQQQSQSRAVLAANARRRDSSHNERFYEEHEYERRVKKRRARLITAAEEAFTHIKRIHNEPAPALPLDPQEAASAVFPSMARALQKYLRVTRQQPRHTFESILKHLAHCLKHDLSPRAFLEPYLTESPVMQSEKERRWVQSWSLICDEIVSRPIGNECTFQLIQNDVSLMVTVHKLPHFNLAEEVVDPKSNKFVLKLNSETSV",
                "length": 581,
                "header": "tr|A1Z7N9-1|A0A0B4KEN4_DROME Computationally mapped isoform of Vang-like protein  OS=Drosophila melanogaster OX=7227 GN=Vang PE=3 SV=1 CANONICAL=A0A0B4KEN4-1"
            },
            "locus": {
                "chromosome": "2R",
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