{ "uniprot_canonical_ac": "A0A0B4KEG0-1", "uniprot_ac": "A0A0B4KEG0", "uniprot_id": "A0A0B4KEG0_DROME", "mass": { "chemical_mass": 46723.0, "monoisotopic_mass": 46723.0 }, "refseq": { "ac": "NP_788288", "name": "uncharacterized protein, isoform A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_788288" }, "gene_names": [ { "name": "Nadk2", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A0A0B4KEG0", "id": "A0A0B4KEG0" }, { "name": "CG30346; Dmel\\CG8080; NADK2", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260815", "id": "NP_001260815" }, { "name": "CG30346", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A0A0B4KEG0", "id": "A0A0B4KEG0" }, { "name": "CG8080", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260815", "id": "NP_001260815" }, { "name": "CG8080", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A0A0B4KEG0", "id": "A0A0B4KEG0" }, { "name": "Dmel\\CG8080", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A0A0B4KEG0", "id": "A0A0B4KEG0" }, { "name": "Dmel_CG8080", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A0A0B4KEG0", "id": "A0A0B4KEG0" } ], "protein_names": [ { "name": "NAD kinase 2, mitochondrial", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "A0A0B4KEG0" }, { "name": "2.7.1.23", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "A0A0B4KEG0" }, { "name": "CG8080-PA", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_788288", "id": "NP_788288" }, { "name": "CG8080-PB", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260815", "id": "NP_001260815" }, { "name": "CG8080-PC", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260816", "id": "NP_001260816" }, { "name": "CG8080-PD", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260817", "id": "NP_001260817" }, { "name": "CG8080-PE", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260818", "id": "NP_001260818" }, { "name": "NAD kinase domain-containing protein 1, mitochondrial", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "A0A0B4KEG0" }, { "name": "uncharacterized protein, isoform A", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_788288", "id": "NP_788288" }, { "name": "uncharacterized protein, isoform B", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260815", "id": "NP_001260815" }, { "name": "uncharacterized protein, isoform C", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260816", "id": "NP_001260816" }, { "name": "uncharacterized protein, isoform D", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260817", "id": "NP_001260817" }, { "name": "uncharacterized protein, isoform E", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260818", "id": "NP_001260818" } ], "function": [ { "annotation": "Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor.", "evidence": [ { "database": "UniProtKB", "id": "Q7JW73", "url": "https://www.uniprot.org/uniprot/Q7JW73#function" }, { "database": "UniProtKB", "id": "PIRNR017565", "url": "https://www.uniprot.org/uniprot/PIRNR017565#function" }, { "database": "UniProtKB", "id": "A0A0B4KFF1", "url": "https://www.uniprot.org/uniprot/A0A0B4KFF1#function" }, { "database": "UniProtKB", "id": "A0A0B4KF27", "url": "https://www.uniprot.org/uniprot/A0A0B4KF27#function" }, { "database": "UniProtKB", "id": "A0A0B4KEH3", "url": "https://www.uniprot.org/uniprot/A0A0B4KEH3#function" }, { "database": "UniProtKB", "id": "A0A0B4KEG0", "url": "https://www.uniprot.org/uniprot/A0A0B4KEG0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KEG0", "url": "https://www.uniprot.org/uniprot/A0A0B4KEG0" } ], "common_name": "Fruit fly" } ], "gene": [ { "name": "Nadk2", "url": "https://www.uniprot.org/uniprot/A0A0B4KEG0", "locus": { "chromosome": "2R", "start_pos": 9089774, "end_pos": 9092893, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0033373", "url": "https://www.ensembl.org/id/FBgn0033373" } ] } } ], "crossref": [ { "id": "FBgn0033373", "url": "https://bgee.org/?page=gene&gene_id=FBgn0033373", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "FBgn0033373", "url": "https://flybase.org/reports/FBgn0033373", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "35918", "url": "https://www.ncbi.nlm.nih.gov/gene/35918", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q7JW73", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q7JW73*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR012355", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012355", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016064", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016064", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017437", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017437", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017438", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017438", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG8080", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+dme:Dmel_CG8080", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CVGVWPN", "url": "https://omabrowser.org/oma/group/CVGVWPN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "231143at2759", "url": "http://www.orthodb.org/?query=231143at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13158:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13158:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PR_Q7JW73", "url": "http://purl.obolibrary.org/obo/PR_Q7JW73", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-DME-196807", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-196807", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "NP_001260818", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260818", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "18629", "url": "https://www.rhea-db.org/rhea/18629", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A0B4KEG0", "url": "https://www.uniprot.org/uniprot/A0A0B4KEG0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0B4KEG0-1", "url": "https://www.uniprot.org/uniprot/A0A0B4KEG0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0B4KEH3", "url": "https://www.uniprot.org/uniprot/A0A0B4KEH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0B4KEH3-1", "url": "https://www.uniprot.org/uniprot/A0A0B4KEH3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0B4KF27", "url": "https://www.uniprot.org/uniprot/A0A0B4KF27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0B4KF27-1", "url": "https://www.uniprot.org/uniprot/A0A0B4KF27-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0B4KFF1", "url": "https://www.uniprot.org/uniprot/A0A0B4KFF1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0B4KFF1-1", "url": "https://www.uniprot.org/uniprot/A0A0B4KFF1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q7JW73", "url": "https://www.uniprot.org/uniprot/Q7JW73", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q7JW73-1", "url": "https://www.uniprot.org/uniprot/Q7JW73-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLQNGRKIIPEGLKYAKYTPTNFKLKRALVVTKLSRYEFEQLRHPELSPDQLQQKLRDRGTDVEMVLHLHKVHKDFERRVVQSFQDVGCEVKLSSRLEFRSSLSKDVMSWADVIVPVGGDGTFLLSAGRASPLFALSQQKTPIVGFNSDPLHSEGRLMLPKHYSDNPADAVSRIKSGDFKWMHRSRVRTTMLGSNGNIPEPTDLFRHTEVKMEQVSTAPEMLDQDMAYKYKAKMKRVLPYLALNEVFIGEHLSARVSHLQLVLDHQDVVNKTKCSGLCVSTGTGSTSWHTSINRITSRDVDDLLRSLPDGDSKNVMMLRQNAEEIAQRYNQGLLFAPDDPRLCYSIREQICVGVWPSPKTFKERDFVQTVFVKSHCIDANLVIDGSISFPFNDGAKALLEVHPEDALLTIALD", "length": 413, "header": "tr|A0A0B4KEG0-1|A0A0B4KEG0_DROME Isoform 1 of NAD kinase 2, mitochondrial OS=Drosophila melanogaster OX=7227 GN=Nadk2 PE=1 SV=1 CANONICAL=A0A0B4KEG0-1" }, "isoforms": [ { "isoform_ac": "A0A0B4KEG0-1", "url": "", "sequence": { "sequence": "MLQNGRKIIPEGLKYAKYTPTNFKLKRALVVTKLSRYEFEQLRHPELSPDQLQQKLRDRGTDVEMVLHLHKVHKDFERRVVQSFQDVGCEVKLSSRLEFRSSLSKDVMSWADVIVPVGGDGTFLLSAGRASPLFALSQQKTPIVGFNSDPLHSEGRLMLPKHYSDNPADAVSRIKSGDFKWMHRSRVRTTMLGSNGNIPEPTDLFRHTEVKMEQVSTAPEMLDQDMAYKYKAKMKRVLPYLALNEVFIGEHLSARVSHLQLVLDHQDVVNKTKCSGLCVSTGTGSTSWHTSINRITSRDVDDLLRSLPDGDSKNVMMLRQNAEEIAQRYNQGLLFAPDDPRLCYSIREQICVGVWPSPKTFKERDFVQTVFVKSHCIDANLVIDGSISFPFNDGAKALLEVHPEDALLTIALD", "length": 413, "header": "tr|A0A0B4KEG0-1|A0A0B4KEG0_DROME Isoform 1 of NAD kinase 2, mitochondrial OS=Drosophila melanogaster OX=7227 GN=Nadk2 PE=1 SV=1 CANONICAL=A0A0B4KEG0-1" }, "locus": { "chromosome": "2R", "start_pos": 9091769, "end_pos": 9089921, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0310146", "url": "https://www.ensembl.org/id/FBtr0310146" }, { "database": "Ensembl Peptide", "id": "FBpp0301831", "url": "https://www.ensembl.org/id/FBpp0301831" } ] } }, { "isoform_ac": "A0A0B4KEH3-1", "url": "", "sequence": { "sequence": "MLQNGRKIIPEGLKYAKYTPTNFKLKRALVVTKLSRYEFEQLRHPELSPDQLQQKLRDRGTDVEMVLHLHKVHKDFERRVVQSFQDVGCEVKLSSRSSLSKDVMSWADVIVPVGGDGTFLLSAGRASPLFALSQQKTPIVGFNSDPLHSEGRLMLPKHYSDNPADAVSRIKSGDFKWMHRSRVRTTMLGSNGNIPEPTDLFRHTEVKMEQVSTAPEMLDQDMAYKYKAKMKRVLPYLALNEVFIGEHLSARVSHLQLVLDHQDVVNKTKCSGLCVSTGTGSTSWHTSINRITSRDVDDLLRSLPDGDSKNVMMLRQNAEEIAQRYNQGLLFAPDDPRLCYSIREQICVGVWPSPKTFKERDFVQTVFVKSHCIDANLVIDGSISFPFNDGAKALLEVHPEDALLTIALD", "length": 409, "header": "tr|A0A0B4KEH3-1|A0A0B4KEH3_DROME Computationally mapped isoform of NAD kinase 2, mitochondrial OS=Drosophila melanogaster OX=7227 GN=Nadk2 PE=1 SV=1 CANONICAL=A0A0B4KEG0-1" }, "locus": { "chromosome": "2R", "start_pos": 9091769, "end_pos": 9089921, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0310145", "url": "https://www.ensembl.org/id/FBtr0310145" }, { "database": "Ensembl Peptide", "id": "FBpp0301830", "url": "https://www.ensembl.org/id/FBpp0301830" } ] } }, { "isoform_ac": "A0A0B4KF27-1", "url": "", "sequence": { "sequence": "MLKSKQLLQQFSKEYAKYTPTNFKLKRALVVTKLSRYEFEQLRHPELSPDQLQQKLRDRGTDVEMVLHLHKVHKDFERRVVQSFQDVGCEVKLSSSSLSKDVMSWADVIVPVGGDGTFLLSAGRASPLFALSQQKTPIVGFNSDPLHSEGRLMLPKHYSDNPADAVSRIKSGDFKWMHRSRVRTTMLGSNGNIPEPTDLFRHTEVKMEQVSTAPEMLDQDMAYKYKAKMKRVLPYLALNEVFIGEHLSARVSHLQLVLDHQDVVNKTKCSGLCVSTGTGSTSWHTSINRITSRDVDDLLRSLPDGDSKNVMMLRQNAEEIAQRYNQGLLFAPDDPRLCYSIREQICVGVWPSPKTFKERDFVQTVFVKSHCIDANLVIDGSISFPFNDGAKALLEVHPEDALLTIALD", "length": 408, "header": "tr|A0A0B4KF27-1|A0A0B4KF27_DROME Computationally mapped isoform of NAD kinase 2, mitochondrial OS=Drosophila melanogaster OX=7227 GN=Nadk2 PE=1 SV=1 CANONICAL=A0A0B4KEG0-1" }, "locus": { "chromosome": "2R", "start_pos": 9092471, "end_pos": 9089921, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0310144", "url": "https://www.ensembl.org/id/FBtr0310144" }, { "database": "Ensembl Peptide", "id": "FBpp0301829", "url": "https://www.ensembl.org/id/FBpp0301829" } ] } }, { "isoform_ac": "A0A0B4KFF1-1", "url": "", "sequence": { "sequence": "MLKSKQLLQQFSKEYAKYTPTNFKLKRALVVTKLSRYEFEQLRHPELSPDQLQQKLRDRGTDVEMVLHLHKVHKDFERRVVQSFQDVGCEVKLSSRSSLSKDVMSWADVIVPVGGDGTFLLSAGRASPLFALSQQKTPIVGFNSDPLHSEGRLMLPKHYSDNPADAVSRIKSGDFKWMHRSRVRTTMLGSNGNIPEPTDLFRHTEVKMEQVSTAPEMLDQDMAYKYKAKMKRVLPYLALNEVFIGEHLSARVSHLQLVLDHQDVVNKTKCSGLCVSTGTGSTSWHTSINRITSRDVDDLLRSLPDGDSKNVMMLRQNAEEIAQRYNQGLLFAPDDPRLCYSIREQICVGVWPSPKTFKERDFVQTVFVKSHCIDANLVIDGSISFPFNDGAKALLEVHPEDALLTIALD", "length": 409, "header": "tr|A0A0B4KFF1-1|A0A0B4KFF1_DROME Computationally mapped isoform of NAD kinase 2, mitochondrial OS=Drosophila melanogaster OX=7227 GN=Nadk2 PE=1 SV=1 CANONICAL=A0A0B4KEG0-1" }, "locus": { "chromosome": "2R", "start_pos": 9092471, "end_pos": 9089921, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0310143", "url": "https://www.ensembl.org/id/FBtr0310143" }, { "database": "Ensembl Peptide", "id": "FBpp0301828", "url": "https://www.ensembl.org/id/FBpp0301828" } ] } }, { "isoform_ac": "Q7JW73-1", "url": "", "sequence": { "sequence": "MLKSKQLLQQFSKEYAKYTPTNFKLKRALVVTKLSRYEFEQLRHPELSPDQLQQKLRDRGTDVEMVLHLHKVHKDFERRVVQSFQDVGCEVKLSSRLEFRSSLSKDVMSWADVIVPVGGDGTFLLSAGRASPLFALSQQKTPIVGFNSDPLHSEGRLMLPKHYSDNPADAVSRIKSGDFKWMHRSRVRTTMLGSNGNIPEPTDLFRHTEVKMEQVSTAPEMLDQDMAYKYKAKMKRVLPYLALNEVFIGEHLSARVSHLQLVLDHQDVVNKTKCSGLCVSTGTGSTSWHTSINRITSRDVDDLLRSLPDGDSKNVMMLRQNAEEIAQRYNQGLLFAPDDPRLCYSIREQICVGVWPSPKTFKERDFVQTVFVKSHCIDANLVIDGSISFPFNDGAKALLEVHPEDALLTIALD", "length": 413, "header": "tr|Q7JW73-1|A0A0B4KEG0_DROME Computationally mapped isoform of NAD kinase 2, mitochondrial OS=Drosophila melanogaster OX=7227 GN=Nadk2 PE=1 SV=1 CANONICAL=A0A0B4KEG0-1" }, "locus": { "chromosome": "2R", "start_pos": 9092471, "end_pos": 9089921, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0088633", "url": "https://www.ensembl.org/id/FBtr0088633" }, { "database": "Ensembl Peptide", "id": "FBpp0087714", "url": "https://www.ensembl.org/id/FBpp0087714" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "dme:Dmel_CG8080", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+dme:Dmel_CG8080", "resource": "KEGG Pathway" }, { "id": "R-DME-196807", "name": "Nicotinate metabolism", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-196807", "resource": "Reactome", "description": "Nicotinate metabolism" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "NADP biosynthetic process", "id": "GO:0006741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006741", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KEG0", "url": "https://www.uniprot.org/uniprot/A0A0B4KEG0" } ], "pmid": "" }, { "name": "phosphorylation", "id": "GO:0016310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016310", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KEG0", "url": "https://www.uniprot.org/uniprot/A0A0B4KEG0" } ], "pmid": "" }, { "name": "NAD metabolic process", "id": "GO:0019674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019674", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KEG0", "url": "https://www.uniprot.org/uniprot/A0A0B4KEG0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "NAD+ kinase activity", "id": "GO:0003951", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003951", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KEG0", "url": "https://www.uniprot.org/uniprot/A0A0B4KEG0" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KEG0", "url": "https://www.uniprot.org/uniprot/A0A0B4KEG0" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KEG0", "url": "https://www.uniprot.org/uniprot/A0A0B4KEG0" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KEG0", "url": "https://www.uniprot.org/uniprot/A0A0B4KEG0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4KEG0", "url": "https://www.uniprot.org/uniprot/A0A0B4KEG0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 270, "end_pos": 272, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "18629", "name": "", "equation": "ATP + NAD(+) = ADP + H(+) + NADP(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q1HCL7-1", "Q4G0N4-1", "O95544-1", "Q8C5H8-1", "P58058-1", "P21373-1", "A0A0B4KEG0-1" ], "evidence": [ { "id": "18629", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/18629" } ] }, { "id": "R-DME-8955030", "name": "NADK2 dimer phosphorylates NAD+ to NADP+", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. 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