{
    "uniprot_canonical_ac": "A0A0B4KEE4-1",
    "uniprot_ac": "A0A0B4KEE4",
    "uniprot_id": "KOI_DROME",
    "mass": {
        "chemical_mass": 109725.0,
        "monoisotopic_mass": 109725.0
    },
    "refseq": {
        "ac": "NP_001260738",
        "name": "klaroid, isoform A",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260738"
    },
    "gene_names": [
        {
            "name": "koi",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KEE4",
            "id": "A0A0B4KEE4"
        },
        {
            "name": "BEST:LD11166; CG18584; CG3287; CG44154; Dmel\\CG44154; Koi; n(2)09967",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_724503",
            "id": "NP_724503"
        },
        {
            "name": "BEST:LD11166",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KEE4",
            "id": "A0A0B4KEE4"
        },
        {
            "name": "CG18584",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KEE4",
            "id": "A0A0B4KEE4"
        },
        {
            "name": "CG3287",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KEE4",
            "id": "A0A0B4KEE4"
        },
        {
            "name": "CG44154",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KEE4",
            "id": "A0A0B4KEE4"
        },
        {
            "name": "Dmel\\CG44154",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KEE4",
            "id": "A0A0B4KEE4"
        },
        {
            "name": "Dmel_CG44154",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KEE4",
            "id": "A0A0B4KEE4"
        },
        {
            "name": "Koi",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KEE4",
            "id": "A0A0B4KEE4"
        },
        {
            "name": "koi",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_724503",
            "id": "NP_724503"
        },
        {
            "name": "n(2)09967",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KEE4",
            "id": "A0A0B4KEE4"
        }
    ],
    "protein_names": [
        {
            "name": "Klaroid protein",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "A0A0B4KEE4"
        },
        {
            "name": "CG44154-PA; koi-PA; klaroid",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260738",
            "id": "NP_001260738"
        },
        {
            "name": "CG44154-PB; koi-PB; klaroid",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_610240",
            "id": "NP_610240"
        },
        {
            "name": "CG44154-PE; koi-PE; klaroid",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_724503",
            "id": "NP_724503"
        },
        {
            "name": "CG44154-PF; koi-PF; klaroid",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260740",
            "id": "NP_001260740"
        },
        {
            "name": "klaroid, isoform A",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260738",
            "id": "NP_001260738"
        },
        {
            "name": "klaroid, isoform B",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_610240",
            "id": "NP_610240"
        },
        {
            "name": "klaroid, isoform E",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_724503",
            "id": "NP_724503"
        },
        {
            "name": "klaroid, isoform F",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260740",
            "id": "NP_001260740"
        }
    ],
    "function": [
        {
            "annotation": "Component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton (By similarity). Is required to nuclear migration in eye and to anchor klar in the nuclear membrane (PubMed:18820457).",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A0B4KEE4",
                    "url": "https://www.uniprot.org/uniprot/A0A0B4KEE4#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "O94901",
                    "url": "https://www.uniprot.org/uniprot/O94901#function"
                },
                {
                    "database": "PubMed",
                    "id": "18820457",
                    "url": "https://glygen.org/publication/PubMed/18820457"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Drosophila melanogaster",
            "taxid": 7227,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A0B4KEE4",
                    "url": "https://www.uniprot.org/uniprot/A0A0B4KEE4"
                }
            ],
            "common_name": "Fruit fly"
        }
    ],
    "gene": [
        {
            "name": "koi",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KEE4",
            "locus": {
                "chromosome": "2R",
                "start_pos": 6818199,
                "end_pos": 6811019,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "FBgn0265003",
                        "url": "https://www.ensembl.org/id/FBgn0265003"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "FBgn0265003",
            "url": "https://bgee.org/?page=gene&gene_id=FBgn0265003",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "FBgn0265003",
            "url": "https://flybase.org/reports/FBgn0265003",
            "database": "FlyBase",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "35594",
            "url": "https://www.ncbi.nlm.nih.gov/gene/35594",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "A1Z6Q1",
            "url": "https://www.ebi.ac.uk/intact/interactors/id:A1Z6Q1*",
            "database": "IntAct",
            "categories": [
                "Other"
            ]
        },
        {
            "id": "IPR012919",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR012919",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR045119",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR045119",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "dme:Dmel_CG44154",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+dme:Dmel_CG44154",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "KLNMASI",
            "url": "https://omabrowser.org/oma/group/KLNMASI/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "39017at2759",
            "url": "http://www.orthodb.org/?query=39017at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR12911",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12911",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR12911:SF8",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12911:SF8",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF07738",
            "url": "http://pfam.xfam.org/family/PF07738",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_A0A0B4KEE4",
            "url": "http://purl.obolibrary.org/obo/PR_A0A0B4KEE4",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "NP_001260738",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001260738",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A0B4KEE4",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KEE4",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A0B4KEE4-1",
            "url": "https://www.uniprot.org/uniprot/A0A0B4KEE4-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A1Z6Q0",
            "url": "https://www.uniprot.org/uniprot/A1Z6Q0",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A1Z6Q0-1",
            "url": "https://www.uniprot.org/uniprot/A1Z6Q0-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A1Z6Q1",
            "url": "https://www.uniprot.org/uniprot/A1Z6Q1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A1Z6Q1-1",
            "url": "https://www.uniprot.org/uniprot/A1Z6Q1-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A4UZ58",
            "url": "https://www.uniprot.org/uniprot/A4UZ58",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A4UZ58-1",
            "url": "https://www.uniprot.org/uniprot/A4UZ58-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MSENTYQIETRRRSRSKTPFLRSSCDHENCEHAGEEGHVHHLKRKSAAPNVQTIIEEHIVESSISKKTRAKAFAQLTSDYSSDDMTPDAKRKQNSITATVTSILTKRSGGATSTPRNRSQLETTQNTLNSAQEKLNQSNGNLSSGNVSDYLAYIEYRDAGEYWNKTPKTDYTYSELSPHRRQLAPGIVAMPNMSRKSLENHNDRVNYMVQQNPAQEEFIRRRYQSKYTQQVNYDSADELDATFGQQKQSWWLIRLIQLVVSSITTVWSRVTNLSATETTAYQNYHAKRQQSQQVGLWWKIVQTIGGGLASLLRYLYVFIGSVLSLDTWLLRSSDAENKSKKRFLIFLLILLPLLLLSGWLLLQEDQRSAYVQRAEALLPLPLSIFGSLRSRFSNAGATLKSWMEVPTVRSPQREAEAIKVNMASIEQNIQKALTAEEYENILNHVNSYVQQLVELKMQQHSKELAPQQIELFVKLMKENLKQIMYKTELSEKDLSDLAIKLKLELQSSGGWQDGAKLSQANLEEITKLIKAEVHLHESHYTIQLDRIDFASLLERILAAPALADFVDARISLRVGELEPKESSGSSDAEVQIERLNREIAFIKLALSDKQAENADLHQSISNLKLGQEDLLERIQQHELSQDRRFHGLLAEIENKLSALNDSQFALLNKQIKLSLVEILGFKQSTAGGSAGQLDDFDLQTWVRSMFVAKDYLEQQLLELNKRTNNNIRDEIERSSILLMSDISQRLKREILLVVEAKHNESTKALKGHIREEEVRQIVKTVLAIYDADKTGLVDFALESAGGQILSTRCTESYQTKSAQISVFGIPLWYPTNTPRVAISPNVQPGECWAFQGFPGFLVLKLNSLVYVTGFTLEHIPKSLSPTGRIESAPRNFTVWGLEQEKDQEPVLFGDYQFEDNGASLQYFAVQNLDIKRPYEIVELRIETNHGHPTYTCLYRFRVHGKPPAT",
        "length": 965,
        "header": "sp|A0A0B4KEE4-1|KOI_DROME Isoform 1 of Klaroid protein  OS=Drosophila melanogaster OX=7227 GN=koi PE=2 SV=1 CANONICAL=A0A0B4KEE4-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A0B4KEE4-1",
            "url": "",
            "sequence": {
                "sequence": "MSENTYQIETRRRSRSKTPFLRSSCDHENCEHAGEEGHVHHLKRKSAAPNVQTIIEEHIVESSISKKTRAKAFAQLTSDYSSDDMTPDAKRKQNSITATVTSILTKRSGGATSTPRNRSQLETTQNTLNSAQEKLNQSNGNLSSGNVSDYLAYIEYRDAGEYWNKTPKTDYTYSELSPHRRQLAPGIVAMPNMSRKSLENHNDRVNYMVQQNPAQEEFIRRRYQSKYTQQVNYDSADELDATFGQQKQSWWLIRLIQLVVSSITTVWSRVTNLSATETTAYQNYHAKRQQSQQVGLWWKIVQTIGGGLASLLRYLYVFIGSVLSLDTWLLRSSDAENKSKKRFLIFLLILLPLLLLSGWLLLQEDQRSAYVQRAEALLPLPLSIFGSLRSRFSNAGATLKSWMEVPTVRSPQREAEAIKVNMASIEQNIQKALTAEEYENILNHVNSYVQQLVELKMQQHSKELAPQQIELFVKLMKENLKQIMYKTELSEKDLSDLAIKLKLELQSSGGWQDGAKLSQANLEEITKLIKAEVHLHESHYTIQLDRIDFASLLERILAAPALADFVDARISLRVGELEPKESSGSSDAEVQIERLNREIAFIKLALSDKQAENADLHQSISNLKLGQEDLLERIQQHELSQDRRFHGLLAEIENKLSALNDSQFALLNKQIKLSLVEILGFKQSTAGGSAGQLDDFDLQTWVRSMFVAKDYLEQQLLELNKRTNNNIRDEIERSSILLMSDISQRLKREILLVVEAKHNESTKALKGHIREEEVRQIVKTVLAIYDADKTGLVDFALESAGGQILSTRCTESYQTKSAQISVFGIPLWYPTNTPRVAISPNVQPGECWAFQGFPGFLVLKLNSLVYVTGFTLEHIPKSLSPTGRIESAPRNFTVWGLEQEKDQEPVLFGDYQFEDNGASLQYFAVQNLDIKRPYEIVELRIETNHGHPTYTCLYRFRVHGKPPAT",
                "length": 965,
                "header": "sp|A0A0B4KEE4-1|KOI_DROME Isoform 1 of Klaroid protein  OS=Drosophila melanogaster OX=7227 GN=koi PE=2 SV=1 CANONICAL=A0A0B4KEE4-1"
            },
            "locus": {
                "chromosome": "2R",
                "start_pos": 6817002,
                "end_pos": 6811929,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "FBtr0335512",
                        "url": "https://www.ensembl.org/id/FBtr0335512"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "FBpp0307480",
                        "url": "https://www.ensembl.org/id/FBpp0307480"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A1Z6Q0-1",
            "url": "",
            "sequence": {
                "sequence": "MSENTYQIETRRRSRSKTPFLRSSCDHENCEHAGEEGHVHHLKRKSAAPNVQTIIEEHIVESSISKKTRAKAFAQLTSDYSSDDMTPDAKRKQNSITATVTSILTKRSGGATSTPRNRSQLETTQNTLNSAQEKLNQSNGNLSSGNVSDYLAYIEYRDAGEYWNKTPKTDYTYSELSPHRRQLAPGIVAMPNMSRKSLENHNDRVNYMVQQNPAQEEFIRRRYQSKYTQQVNYDSADELDATFGQQKQSWWLIRLIQLVVSSITTVWSRVTNLSATETTAYQNYHAKRQQSQQVGLWWKIVQTIGGGLASLLRYLYVFIGSVLSLDTWLLRSSDAENKSKKRFLIFLLILLPLLLLSGLFYYIHPNETFPPKSLSEYTFTLPELPKIDVKDYLNQEQFESLRSQAAEHAVRVRDWADDYVLYLRTIGQNVVNKGRQLFQGDDKVYYERV",
                "length": 449,
                "header": "tr|A1Z6Q0-1|A1Z6Q0_DROME Computationally mapped isoform of Klaroid, isoform F  OS=Drosophila melanogaster OX=7227 GN=koi PE=1 SV=1 CANONICAL=A0A0B4KEE4-1"
            },
            "locus": {
                "chromosome": "2R",
                "start_pos": 6814311,
                "end_pos": 6811929,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "FBtr0335515",
                        "url": "https://www.ensembl.org/id/FBtr0335515"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "FBpp0307483",
                        "url": "https://www.ensembl.org/id/FBpp0307483"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A1Z6Q1-1",
            "url": "",
            "sequence": {
                "sequence": "MTPDAKRKQNSITATVTSILTKRSGGATSTPRNRSQLETTQNTLNSAQEKLNQSNGNLSSGNVSDYLAYIEYRDAGEYWNKTPKTDYTYSELSPHRRQLAPGIVAMPNMSRKSLENHNDRVNYMVQQNPAQEEFIRRRYQSKYTQQVNYDSADELDATFGQQKQSWWLIRLIQLVVSSITTVWSRVTNLSATETTAYQNYHAKRQQSQQVGLWWKIVQTIGGGLASLLRYLYVFIGSVLSLDTWLLRSSDAENKSKKRFLIFLLILLPLLLLSGWLLLQEDQRSAYVQRAEALLPLPLSIFGSLRSRFSNAGATLKSWMEVPTVRSPQREAEAIKVNMASIEQNIQKALTAEEYENILNHVNSYVQQLVELKMQQHSKELAPQQIELFVKLMKENLKQIMYKTELSEKDLSDLAIKLKLELQSSGGWQDGAKLSQANLEEITKLIKAEVHLHESHYTIQLDRIDFASLLERILAAPALADFVDARISLRVGELEPKESSGSSDAEVQIERLNREIAFIKLALSDKQAENADLHQSISNLKLGQEDLLERIQQHELSQDRRFHGLLAEIENKLSALNDSQFALLNKQIKLSLVEILGFKQSTAGGSAGQLDDFDLQTWVRSMFVAKDYLEQQLLELNKRTNNNIRDEIERSSILLMSDISQRLKREILLVVEAKHNESTKALKGHIREEEVRQIVKTVLAIYDADKTGLVDFALESAGGQILSTRCTESYQTKSAQISVFGIPLWYPTNTPRVAISPNVQPGECWAFQGFPGFLVLKLNSLVYVTGFTLEHIPKSLSPTGRIESAPRNFTVWGLEQEKDQEPVLFGDYQFEDNGASLQYFAVQNLDIKRPYEIVELRIETNHGHPTYTCLYRFRVHGKPPAT",
                "length": 881,
                "header": "tr|A1Z6Q1-1|A1Z6Q1_DROME Computationally mapped isoform of Klaroid, isoform B  OS=Drosophila melanogaster OX=7227 GN=koi PE=1 SV=2 CANONICAL=A0A0B4KEE4-1"
            },
            "locus": {
                "chromosome": "2R",
                "start_pos": 6817002,
                "end_pos": 6812878,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "FBtr0335513",
                        "url": "https://www.ensembl.org/id/FBtr0335513"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "FBpp0307481",
                        "url": "https://www.ensembl.org/id/FBpp0307481"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A4UZ58-1",
            "url": "",
            "sequence": {
                "sequence": "MTPDAKRKQNSITATVTSILTKRSGGATSTPRNRSQLETTQNTLNSAQEKLNQSNGNLSSGNVSDYLAYIEYRDAGEYWNKTPKTDYTYSELSPHRRQLAPGIVAMPNMSRKSLENHNDRVNYMVQQNPAQEEFIRRRYQSKYTQQVNYDSADELDATFGQQKQSWWLIRLIQLVVSSITTVWSRVTNLSATETTAYQNYHAKRQQSQQVGLWWKIVQTIGGGLASLLRYLYVFIGSVLSLDTWLLRSSDAENKSKKRFLIFLLILLPLLLLSGLFYYIHPNETFPPKSLSEYTFTLPELPKIDVKDYLNQEQFESLRSQAAEHAVRVRDWADDYVLYLRTIGQNVVNKGRQLFQGDDKVYYERV",
                "length": 365,
                "header": "tr|A4UZ58-1|KOI_DROME Computationally mapped isoform of Klaroid protein  OS=Drosophila melanogaster OX=7227 GN=koi PE=2 SV=1 CANONICAL=A0A0B4KEE4-1"
            },
            "locus": {
                "chromosome": "2R",
                "start_pos": 6814311,
                "end_pos": 6812878,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "FBtr0335516",
                        "url": "https://www.ensembl.org/id/FBtr0335516"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "FBpp0307484",
                        "url": "https://www.ensembl.org/id/FBpp0307484"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [
        {
            "title": "Drosophila klaroid encodes a SUN domain protein required for Klarsicht localization to the nuclear envelope and nuclear migration in the eye.",
            "journal": "Fly",
            "date": "2007",
            "authors": "Kracklauer Martin P, Banks Susan M L, Xie Xuanhua, Wu Yaning, Fischer Janice A",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A0B4KEE4",
                    "url": "https://www.uniprot.org/uniprot/A0A0B4KEE4"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "18820457",
                    "url": "https://glygen.org/publication/PubMed/18820457"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "dme:Dmel_CG44154",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+dme:Dmel_CG44154",
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