{ "uniprot_canonical_ac": "A0A0B4JCU3-1", "uniprot_ac": "A0A0B4JCU3", "uniprot_id": "A0A0B4JCU3_DROME", "mass": { "chemical_mass": 80674.0, "monoisotopic_mass": 80674.0 }, "refseq": { "ac": "NP_726271", "name": "receptor expression enhancing protein A, isoform D", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_726271" }, "gene_names": [ { "name": "ReepA", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A0A0B4JCU3", "id": "A0A0B4JCU3" }, { "name": "BcDNA:LD42159", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A0A0B4JCU3", "id": "A0A0B4JCU3" }, { "name": "BcDNA:RE29641", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A0A0B4JCU3", "id": "A0A0B4JCU3" }, { "name": "CG30190;CG30193", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A0A0B4JCU3", "id": "A0A0B4JCU3" }, { "name": "CG30190", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A0A0B4JCU3", "id": "A0A0B4JCU3" }, { "name": "CG30193", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A0A0B4JCU3", "id": "A0A0B4JCU3" }, { "name": "CG42678", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A0A0B4JCU3", "id": "A0A0B4JCU3" }, { "name": "CG9848", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A0A0B4JCU3", "id": "A0A0B4JCU3" }, { "name": "D-reep1", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A0A0B4JCU3", "id": "A0A0B4JCU3" }, { "name": "Dmel\\CG42678", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A0A0B4JCU3", "id": "A0A0B4JCU3" }, { "name": "Dmel_CG42678", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A0A0B4JCU3", "id": "A0A0B4JCU3" }, { "name": "Reep1", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A0A0B4JCU3", "id": "A0A0B4JCU3" }, { "name": "ReepA", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001286750", "id": "NP_001286750" }, { "name": "anon-WO0118547.113; BcDNA:LD42159; BcDNA:RE29641; CG30190; CG30193; CG42678; CG9848; D-reep1; Dmel\\CG42678; reep1; Reep1; REEP1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001286750", "id": "NP_001286750" }, { "name": "anon-WO0118547.113", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A0A0B4JCU3", "id": "A0A0B4JCU3" }, { "name": "reep1", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A0A0B4JCU3", "id": "A0A0B4JCU3" } ], "protein_names": [ { "name": "CG42678-PD; ReepA-PD; REEP1 homolog; REEP1 ortholog; receptor expression enhancing protein 1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_726271", "id": "NP_726271" }, { "name": "CG42678-PG; ReepA-PG; REEP1 homolog; REEP1 ortholog; receptor expression enhancing protein 1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097425", "id": "NP_001097425" }, { "name": "CG42678-PH; ReepA-PH; REEP1 homolog; REEP1 ortholog; receptor expression enhancing protein 1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188987", "id": "NP_001188987" }, { "name": "CG42678-PI; ReepA-PI; REEP1 homolog; REEP1 ortholog; receptor expression enhancing protein 1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188988", "id": "NP_001188988" }, { "name": "CG42678-PJ; ReepA-PJ; REEP1 homolog; REEP1 ortholog; receptor expression enhancing protein 1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188989", "id": "NP_001188989" }, { "name": "CG42678-PK; ReepA-PK; REEP1 homolog; REEP1 ortholog; receptor expression enhancing protein 1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611737", "id": "NP_611737" }, { "name": "CG42678-PL; ReepA-PL; REEP1 homolog; REEP1 ortholog; receptor expression enhancing protein 1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097426", "id": "NP_001097426" }, { "name": "CG42678-PO; ReepA-PO; REEP1 homolog; REEP1 ortholog; receptor expression enhancing protein 1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261144", "id": "NP_001261144" }, { "name": "CG42678-PP; ReepA-PP; REEP1 homolog; REEP1 ortholog; receptor expression enhancing protein 1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188990", "id": "NP_001188990" }, { "name": "CG42678-PQ; ReepA-PQ; REEP1 homolog; REEP1 ortholog; receptor expression enhancing protein 1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001286749", "id": "NP_001286749" }, { "name": "CG42678-PR; ReepA-PR; REEP1 homolog; REEP1 ortholog; receptor expression enhancing protein 1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001286750", "id": "NP_001286750" }, { "name": "CG42678-PS; ReepA-PS; REEP1 homolog; REEP1 ortholog; receptor expression enhancing protein 1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001286751", "id": "NP_001286751" }, { "name": "Receptor expression enhancing protein A, isoform I", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "A0A0B4JCU3" }, { "name": "receptor expression enhancing protein A, isoform D", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_726271", "id": "NP_726271" }, { "name": "receptor expression enhancing protein A, isoform G", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097425", "id": "NP_001097425" }, { "name": "receptor expression enhancing protein A, isoform H", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188987", "id": "NP_001188987" }, { "name": "receptor expression enhancing protein A, isoform I", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188988", "id": "NP_001188988" }, { "name": "receptor expression enhancing protein A, isoform J", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188989", "id": "NP_001188989" }, { "name": "receptor expression enhancing protein A, isoform K", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611737", "id": "NP_611737" }, { "name": "receptor expression enhancing protein A, isoform L", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001097426", "id": "NP_001097426" }, { "name": "receptor expression enhancing protein A, isoform O", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261144", "id": "NP_001261144" }, { "name": "receptor expression enhancing protein A, isoform P", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188990", "id": "NP_001188990" }, { "name": "receptor expression enhancing protein A, isoform Q", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001286749", "id": "NP_001286749" }, { "name": "receptor expression enhancing protein A, isoform R", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001286750", "id": "NP_001286750" }, { "name": "receptor expression enhancing protein A, isoform S", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001286751", "id": "NP_001286751" } ], "function": [], "disease": [ { "disease_id": "DOID:0110782", "recommended_name": { "id": "DOID:0110782", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0110782", "name": "hereditary spastic paraplegia 31", "description": "A hereditary spastic paraplegia that has_material_basis_in mutation in the REEP1 gene on chromosome 2p11." }, "synonyms": [ { "id": "DOID:0110782", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0110782", "name": "SPG31", "description": "" }, { "id": "DOID:0110782", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0110782", "name": "autosomal dominant spastic paraplegia 31", "description": "" }, { "id": "DOID:0110782", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0110782", "name": "autosomal dominant spastic paraplegia type 31", "description": "" }, { "id": "MONDO:0012453", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012453", "name": "hereditary spastic paraplegia 31", "description": "A rare type of hereditary spastic paraplegia usually characterized by a pure phenotype of proximal weakness of the lower extremities with spastic gait and brisk reflexes, with a bimodal age of onset of either childhood or adulthood (>30 years). In some cases, it can present as a complex phenotype with additional associated manifestations including peripheral neuropathy, bulbar palsy (with dysarthria and dysphagia), distal amyotrophy, and impaired distal vibration sense." }, { "id": "MONDO:0012453", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012453", "name": "REEP1 hereditary spastic paraplegia", "description": "" }, { "id": "MONDO:0012453", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012453", "name": "SPG31", "description": "" }, { "id": "MONDO:0012453", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012453", "name": "autosomal dominant spastic paraplegia 31", "description": "" }, { "id": "MONDO:0012453", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012453", "name": "autosomal dominant spastic paraplegia type 31", "description": "" }, { "id": "MONDO:0012453", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012453", "name": "hereditary spastic paraplegia caused by mutation in REEP1", "description": "" }, { "id": "MONDO:0012453", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012453", "name": "hereditary spastic paraplegia type 31", "description": "" }, { "id": "MONDO:0012453", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012453", "name": "spastic paraplegia 31", "description": "" }, { "id": "MONDO:0012453", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012453", "name": "spastic paraplegia 31, autosomal dominant", "description": "" }, { "id": "MIM:610250", "resource": "MIM", "url": "https://www.omim.org/entry/610250", "name": "Spastic paraplegia 31, autosomal dominant", "description": "Spastic paraplegia 31, autosomal dominant" } ], "evidence": [ { "id": "0110782", "database": "Alliance of Genome Resources", "url": 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"description": "" }, { "id": "MONDO:0013884", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013884", "name": "HMN 5B", "description": "" }, { "id": "MONDO:0013884", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013884", "name": "HMN5B", "description": "" }, { "id": "MONDO:0013884", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013884", "name": "dHMN 5B", "description": "" }, { "id": "MONDO:0013884", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013884", "name": "neuronopathy, distal hereditary motor, type VB", "description": "" }, { "id": "MONDO:0013884", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013884", "name": "neuropathy, distal hereditary motor, type 5B", "description": "" }, { "id": "MONDO:0013884", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013884", "name": "spinal muscular atrophy, distal, type 5B", 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[ "Protein" ] }, { "id": "A0A0B4JCV3", "url": "https://www.uniprot.org/uniprot/A0A0B4JCV3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0B4JCV3-1", "url": "https://www.uniprot.org/uniprot/A0A0B4JCV3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0B4JD44", "url": "https://www.uniprot.org/uniprot/A0A0B4JD44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0B4JD44-1", "url": "https://www.uniprot.org/uniprot/A0A0B4JD44-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0B4JD87", "url": "https://www.uniprot.org/uniprot/A0A0B4JD87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0B4JD87-1", "url": "https://www.uniprot.org/uniprot/A0A0B4JD87-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0B4KEX8", "url": "https://www.uniprot.org/uniprot/A0A0B4KEX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0B4KEX8-1", "url": "https://www.uniprot.org/uniprot/A0A0B4KEX8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0B4LG73", "url": "https://www.uniprot.org/uniprot/A0A0B4LG73", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0B4LG73-1", "url": "https://www.uniprot.org/uniprot/A0A0B4LG73-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0B4LG90", "url": "https://www.uniprot.org/uniprot/A0A0B4LG90", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0B4LG90-1", "url": "https://www.uniprot.org/uniprot/A0A0B4LG90-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0B4LH91", "url": "https://www.uniprot.org/uniprot/A0A0B4LH91", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0B4LH91-1", "url": "https://www.uniprot.org/uniprot/A0A0B4LH91-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A8DYN0", "url": "https://www.uniprot.org/uniprot/A8DYN0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A8DYN0-1", "url": "https://www.uniprot.org/uniprot/A8DYN0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q7JRH2", "url": "https://www.uniprot.org/uniprot/Q7JRH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q7JRH2-1", "url": "https://www.uniprot.org/uniprot/Q7JRH2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q8SX60", "url": "https://www.uniprot.org/uniprot/Q8SX60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q8SX60-1", "url": "https://www.uniprot.org/uniprot/Q8SX60-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W1X3", "url": "https://www.uniprot.org/uniprot/Q9W1X3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W1X3-1", "url": "https://www.uniprot.org/uniprot/Q9W1X3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRPIYQQEPPLFYQRPANLRRLRHPPGTVYGRSYSLEDQPEDVIPVYPKFIYAPQQQQQQQRAPYPLYQLGDSLSSLDSDFPENEYAGAYIVEDRVPLANAPTPKVVQNLNALGRMLELLQRCPLPCLSFNTACICSLIVIFLAPRTCAQSLLFPAFRLFCGTLYPAYASYKAVRTKDVKEYVKWMMYWIVFAFFTCIETFTDIFISWLPFYYEVKVALVFWLLSPATKGSSTLYRKFVHPMLTRHEQEIDEYVNQAKERGYSAVLQLGSKGVNYATNVLMQTAIKGGGNLVQTIKRSYSLSDLSEPDMHRTQDELDDVMMSSMTSSAVVMRSTATGARLLRPRNQTPVGRSGSGTRHSTGMYFTEVDVTAKNAGDFNYNIRSQDDISSGYSSAEPVSGLSRTSSMTNASKARAKSKRNELLEEMRDEVYLDNQLYFQGVQRKSSVPEAEELKIVESSESIQSQELEKVLKEENIDAEDEAFFETLPLIEEHINEVVANYGRDEKLLPQERKHNSIEEEQFEDALFEEPQKCVSDEVDAKNIEEILTDRSQNQTPNGSAETTDSGTPSQNKPYVHPPIDPFLLVLSASASAPDPFMPERPRPMSPREMRETLEEIKHSFRAQLEAEPSVSASPSPSLRPKANHGKGRAPPPPLPPKKHSLSPQPDAISQTSTGSVERKSGIGQLFKNIKANVLRNKANPSQQQPEDEQLAAKETQI", "length": 716, "header": "tr|A0A0B4JCU3-1|A0A0B4JCU3_DROME Isoform 1 of Receptor expression enhancing protein A, isoform I OS=Drosophila melanogaster OX=7227 GN=ReepA PE=1 SV=1 CANONICAL=A0A0B4JCU3-1" }, "isoforms": [ { "isoform_ac": "A0A0B4JCU3-1", "url": "", "sequence": { "sequence": "MRPIYQQEPPLFYQRPANLRRLRHPPGTVYGRSYSLEDQPEDVIPVYPKFIYAPQQQQQQQRAPYPLYQLGDSLSSLDSDFPENEYAGAYIVEDRVPLANAPTPKVVQNLNALGRMLELLQRCPLPCLSFNTACICSLIVIFLAPRTCAQSLLFPAFRLFCGTLYPAYASYKAVRTKDVKEYVKWMMYWIVFAFFTCIETFTDIFISWLPFYYEVKVALVFWLLSPATKGSSTLYRKFVHPMLTRHEQEIDEYVNQAKERGYSAVLQLGSKGVNYATNVLMQTAIKGGGNLVQTIKRSYSLSDLSEPDMHRTQDELDDVMMSSMTSSAVVMRSTATGARLLRPRNQTPVGRSGSGTRHSTGMYFTEVDVTAKNAGDFNYNIRSQDDISSGYSSAEPVSGLSRTSSMTNASKARAKSKRNELLEEMRDEVYLDNQLYFQGVQRKSSVPEAEELKIVESSESIQSQELEKVLKEENIDAEDEAFFETLPLIEEHINEVVANYGRDEKLLPQERKHNSIEEEQFEDALFEEPQKCVSDEVDAKNIEEILTDRSQNQTPNGSAETTDSGTPSQNKPYVHPPIDPFLLVLSASASAPDPFMPERPRPMSPREMRETLEEIKHSFRAQLEAEPSVSASPSPSLRPKANHGKGRAPPPPLPPKKHSLSPQPDAISQTSTGSVERKSGIGQLFKNIKANVLRNKANPSQQQPEDEQLAAKETQI", "length": 716, "header": "tr|A0A0B4JCU3-1|A0A0B4JCU3_DROME Isoform 1 of Receptor expression enhancing protein A, isoform I OS=Drosophila melanogaster OX=7227 GN=ReepA PE=1 SV=1 CANONICAL=A0A0B4JCU3-1" }, "locus": { "chromosome": "2R", "start_pos": 22931276, "end_pos": 22926626, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0302770", "url": "https://www.ensembl.org/id/FBtr0302770" }, { "database": "Ensembl Peptide", "id": "FBpp0291910", "url": "https://www.ensembl.org/id/FBpp0291910" } ] } }, { "isoform_ac": "A0A0B4JCV3-1", "url": "", "sequence": { "sequence": "MISSLFSRLIILFCGTLYPAYASYKAVRTKDVKEYVKWMMYWIVFAFFTCIETFTDIFISWLPFYYEVKVALVFWLLSPATKGSSTLYRKFVHPMLTRHEQEIDEYVNQAKERGYSAVLQLGSKGVNYATNVLMQTAIKGGGNLVQTIKRSYSLSDLSEPDMHRTQDELDDVMMSSMTSSAVVMRSTATGARLLRPRNQTPVGRSGSGTRHSTGMYFTEVDVTAKNAGDFNYNIRSQDDISSGYSSAEPVSGLSRTSSMTNASKARAKSKRNELLEEMRDEVYLDNQLYFQGVQRKSSVPEAEELKIVESSESIQSQELEKVLKEENIDAEDEAFFETLPLIEEHINEVVANYGRDEKLLPQERKHNSIEEEQFEDALFEEPQKCVSDEVDAKNIEEILTDRSQNQTPNGSAETTDSGTPSQNKPYVHPPIDPFLLVLSASASAPDPFMPERPRPMSPREMRETLEEIKHSFRAQLEAEPSVSASPSPSLRPKANHGKGRAPPPPLPPKKHSLSPQPDAISQTSTGSVERKSGQIHVC", "length": 538, "header": "tr|A0A0B4JCV3-1|A0A0B4JCU3_DROME Computationally mapped isoform of Receptor expression enhancing protein A, isoform I OS=Drosophila melanogaster OX=7227 GN=ReepA PE=1 SV=1 CANONICAL=A0A0B4JCU3-1" }, "locus": { "chromosome": "2R", "start_pos": 22931531, "end_pos": 22925581, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0344190", "url": "https://www.ensembl.org/id/FBtr0344190" }, { "database": "Ensembl Peptide", "id": "FBpp0310602", "url": "https://www.ensembl.org/id/FBpp0310602" } ] } }, { "isoform_ac": "A0A0B4JD44-1", "url": "", "sequence": { "sequence": "MISSLFSRLIILFCGTLYPAYASYKAVRTKDVKEYVKWMMYWIVFAFFTCIETFTDIFISWLPFYYEVKVALVFWLLSPATKGSSTLYRKFVHPMLTRHEQEIDEYVNQAKERGYSAVLQLGSKGVNYATNVLMQTAIKGGGNLVQTIKRSYSLSDLSEPDMHRTQDELDDVMMSSMTSSAVVMRSTATGARLLRPRNQTPVGRSGSGTRHSTGMYFTEVDVTAKNAGDFNYNIRSQDDISSGYSSAEPVSGLSRTSSMTNASKARAKSKRNELLEEMRDEVYLDNQLYFQGVQRKSSVPEAEELKIVESSESIQSQELEKVLKEENIDAEDEAFFETLPLIEEHINEVVANYGRDEKLLPQERKHNSIEEEQFEDALFEEPQKCVSDEVDAKNIEEILTDRSQNQTPNGSAETTDSGTPSQNKPYVHPPIDPFLLVLSASASAPDPFMPERPRPMSPREMRETLEEIKHSFRAQLEAEPSVSASPSPSLRPKANHGKGRAPPPPLPPKKHSLSPQPDAISQTSTGSVERKSGIGQLFKNIKANVLRNKANPSQQQPEDEQLAAKETQI", "length": 569, "header": "tr|A0A0B4JD44-1|A0A0B4JD44_DROME Computationally mapped isoform of Receptor expression enhancing protein A, isoform H OS=Drosophila melanogaster OX=7227 GN=ReepA PE=1 SV=1 CANONICAL=A0A0B4JCU3-1" }, "locus": { "chromosome": "2R", "start_pos": 22931276, "end_pos": 22925581, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0302769", "url": "https://www.ensembl.org/id/FBtr0302769" }, { "database": "Ensembl Peptide", "id": "FBpp0291909", "url": "https://www.ensembl.org/id/FBpp0291909" } ] } }, { "isoform_ac": "A0A0B4JD87-1", "url": "", "sequence": { "sequence": "MISSLFSRLIILFCGTLYPAYASYKAVRTKDVKEYVKWMMYWIVFAFFTCIETFTDIFISWLPFYYEVKVALVFWLLSPATKGSSTLYRKFVHPMLTRHEQEIDEYVNQAKERGYSAVLQLGSKGVNYATNVLMQTAIKGGGNLVQTIKRSYSLSDLSEPDMHRTQDELDDVMMSSMTSSAVVMRSTATGARLLRPRNQTPVGRSGSGTRHSTGMYFTEVDVTAKNAGDFNYNIRSQDDISSGYSSAEPVSGLSRTSSMTNASKARAKSKRNEQLLEEMRDEVYLDNQLYFQGVQRKSSVPEAEELKIVESSESIQSQELEKVLKEENIDAEDEAFFETLPLIEEHINEVVANYGRDEKLLPQERKHNSIEEEQFEDALFEEPQKCVSDEVDAKNIEEILTDRSQNQTPNGSAETTDSGTPSQNKPYVHPPIDPFLLVLSASASAPDPFMPERPRPMSPREMRETLEEIKHSFRAQLEAEPSVSASPSPSLRPKANHGKGRAPPPPLPPKKHSLSPQPDAISQTSTGSVERKSGIGQLFKNIKANVLRNKANPSQQQPEDEQLAAKETQI", "length": 570, "header": "tr|A0A0B4JD87-1|A0A0B4JCU3_DROME Computationally mapped isoform of Receptor expression enhancing protein A, isoform I OS=Drosophila melanogaster OX=7227 GN=ReepA PE=1 SV=1 CANONICAL=A0A0B4JCU3-1" }, "locus": { "chromosome": "2R", "start_pos": 22931276, "end_pos": 22925581, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0302771", "url": "https://www.ensembl.org/id/FBtr0302771" }, { "database": "Ensembl Peptide", "id": "FBpp0291911", "url": "https://www.ensembl.org/id/FBpp0291911" } ] } }, { "isoform_ac": "A0A0B4KEX8-1", "url": "", "sequence": { "sequence": "MRPIYQQEPPLFYQRPANLRRLRHPPGTVYGRSYSLEDQPEDVIPVYPKFIYAPQQQQQQQRAPYPLYQLGDSLSSLDSDFPENEYAGAYIVEDRVPLANAPTPKVVQNLNALGRMLELLQRCPLPCLSFNTACICSLIVIFLAPRTCAQSLLFPAFRLFCGTLYPAYASYKAVRTKDVKEYVKWMMYWIVFAFFTCIETFTDIFISWLPFYYEVKVALVFWLLSPATKGSSTLYRKFVHPMLTRHEQEIDEYVNQAKERGYSAVLQLGSKGVNYATNVLMQTAIKRRCIK", "length": 291, "header": "tr|A0A0B4KEX8-1|A0A0B4KEX8_DROME Computationally mapped isoform of Receptor expression-enhancing protein OS=Drosophila melanogaster OX=7227 GN=ReepA PE=1 SV=1 CANONICAL=A0A0B4JCU3-1" }, "locus": { "chromosome": "2R", "start_pos": 22927774, "end_pos": 22926626, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0336697", "url": "https://www.ensembl.org/id/FBtr0336697" }, { "database": "Ensembl Peptide", "id": "FBpp0307678", "url": "https://www.ensembl.org/id/FBpp0307678" } ] } }, { "isoform_ac": "A0A0B4LG73-1", "url": "", "sequence": { "sequence": "MISSLFSRLIILFCGTLYPAYASYKAVRTKDVKEYVKWMMYWIVFAFFTCIETFTDIFISWLPFYYEVKVALVFWLLSPATKGSSTLYRKFVHPMLTRHEQEIDEYVNQAKERGYSAVLQLGSKGVNYATNVLMQTAIKGGGNLVQTIKRSYSLSDLSEPDMHRTQDELDDVMMSSMTSSAVVMRSTATGARLLRPRNQTPVGRSGSGTRHSTGMYFTEVDVTAKNAGDFNYNIRSQDDISSGYSSAEPVSGLSRTSSMTNASKARAKSKRNEDKSMSASCTTLPRSSSRKSERSQGGTATGQMKTRNKSEK", "length": 312, "header": "tr|A0A0B4LG73-1|A0A0B4JCU3_DROME Computationally mapped isoform of Receptor expression enhancing protein A, isoform I OS=Drosophila melanogaster OX=7227 GN=ReepA PE=1 SV=1 CANONICAL=A0A0B4JCU3-1" }, "locus": { "chromosome": "2R", "start_pos": 22931631, "end_pos": 22925581, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0345079", "url": "https://www.ensembl.org/id/FBtr0345079" }, { "database": "Ensembl Peptide", "id": "FBpp0311309", "url": "https://www.ensembl.org/id/FBpp0311309" } ] } }, { "isoform_ac": "A0A0B4LG90-1", "url": "", "sequence": { "sequence": "MRPIYQQEPPLFYQRPANLRRLRHPPGTVYGRSYSLEDQPEDVIPVYPKFIYAPQQQQQQQRAPYPLYQLGDSLSSLDSDFPENEYAGAYIVEDRVPLANAPTPKVVQNLNALGRMLELLQRCPLPCLSFNTACICSLIVIFLAPRTCAQSLLFPAFRLFCGTLYPAYASYKAVRTKDVKEYVKWMMYWIVFAFFTCIETFTDIFISWLPFYYEVKVALVFWLLSPATKGSSTLYRKFVHPMLTRHEQEIDEYVNQAKERGYSAVLQLGSKGVNYATNVLMQTAIKGGGNLVQTIKRSYSLSDLSEPDMHRTQDELDDVMMSSMTSSAVVMRSTATGARLLRPRNQTPVGRSGSGTRHSTGMYFTEVDVTAKNAGDFNYNIRSQDDISSGYSSAEPVSGLSRTSSMTNASKARAKSKRNEDKSMSASCTTLPRSSSRKSERSQGGTATGQMKTRNKSEK", "length": 459, "header": "tr|A0A0B4LG90-1|A0A0B4JCU3_DROME Computationally mapped isoform of Receptor expression enhancing protein A, isoform I OS=Drosophila melanogaster OX=7227 GN=ReepA PE=1 SV=1 CANONICAL=A0A0B4JCU3-1" }, "locus": { "chromosome": "2R", "start_pos": 22931631, "end_pos": 22926626, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0345078", "url": "https://www.ensembl.org/id/FBtr0345078" }, { "database": "Ensembl Peptide", "id": "FBpp0311308", "url": "https://www.ensembl.org/id/FBpp0311308" } ] } }, { "isoform_ac": "A0A0B4LH91-1", "url": "", "sequence": { "sequence": "MRPIYQQEPPLFYQRPANLRRLRHPPGTVYGRSYSLEDQPEDVIPVYPKFIYAPQQQQQQQRAPYPLYQLGDSLSSLDSDFPENEYAGAYIVEDRVPLANAPTPKVVQNLNALGRMLELLQRCPLPCLSFNTACICSLIVIFLAPRTCAQSLLFPAFRLFCGTLYPAYASYKAVRTKDVKEYVKWMMYWIVFAFFTCIETFTDIFISWLPFYYEVKVALVFWLLSPATKGSSTLYRKFVHPMLTRHEQEIDEYVNQAKERGYSAVLQLGSKGVNYATNVLMQTAIKGGGNLVQTIKRSYSLSDLSEPDMHRTQDELDDVMMSSMTSSAVVMRSTATGARLLRPRNQTPVGRSGSGTRHSTGMYFTEVDVTAKNAGDFNYNIRSQDDISSGYSSAEPVSGLSRTSSMTNASKARAKSKRNELLEEMRDEVYLDNQLYFQGVQRKSSVPEAEELKIVESSESIQSQELEKVLKEENIDAEDEAFFETLPLIEEHINEVVANYGRDEKLLPQERKHNSIEEEQFEDALFEEPQKCVSDEVDAKNIEEILTDRSQNQTPNGSAETTDSGTPSQNKPYVHPPIDPFLLVLSASASAPDPFMPERPRPMSPREMRETLEEIKHSFRAQLEAEPSVSASPSPSLRPKANHGKGRAPPPPLPPKKHSLSPQPDAISQTSTGSVERKSGQIHVC", "length": 685, "header": "tr|A0A0B4LH91-1|A0A0B4LH91_DROME Computationally mapped isoform of Receptor expression enhancing protein A, isoform Q OS=Drosophila melanogaster OX=7227 GN=ReepA PE=1 SV=1 CANONICAL=A0A0B4JCU3-1" }, "locus": { "chromosome": "2R", "start_pos": 22931531, "end_pos": 22926626, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0345077", "url": "https://www.ensembl.org/id/FBtr0345077" }, { "database": "Ensembl Peptide", "id": "FBpp0311307", "url": "https://www.ensembl.org/id/FBpp0311307" } ] } }, { "isoform_ac": "A8DYN0-1", "url": "", "sequence": { "sequence": "MHRTQDELDDVMMSSMTSSAVVMRSTATGARLLRPRNQTPVGRSGSGTRHSTGMYFTEVDVTAKNAGDFNYNIRSQDDISSGYSSAEPVSGLSRTSSMTNASKARAKSKRNEDKSMSASCTTLPRSSSRKSERSQGGTATGQMKTRNKSEK", "length": 151, "header": "tr|A8DYN0-1|A0A0B4JCU3_DROME Computationally mapped isoform of Receptor expression enhancing protein A, isoform I OS=Drosophila melanogaster OX=7227 GN=ReepA PE=1 SV=1 CANONICAL=A0A0B4JCU3-1" }, "locus": { "chromosome": "2R", "start_pos": 22931631, "end_pos": 22929865, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0302773", "url": "https://www.ensembl.org/id/FBtr0302773" }, { "database": "Ensembl Peptide", "id": "FBpp0291913", "url": "https://www.ensembl.org/id/FBpp0291913" } ] } }, { "isoform_ac": "Q7JRH2-1", "url": "", "sequence": { "sequence": "MISSLFSRLIILFCGTLYPAYASYKAVRTKDVKEYVKWMMYWIVFAFFTCIETFTDIFISWLPFYYEVKVALVFWLLSPATKGSSTLYRKFVHPMLTRHEQEIDEYVNQAKERGYSAVLQLGSKGVNYATNVLMQTAIKTYALTTAPSGHGRGLQNSHSADELYRGQDTMDSTENWLPRASSLSSIESYTETIYEPRTETKRLVIREVSEEAEFDDDPLGDAGAARLRDMPVRKAQPRRAASTAKAAGKRGQKHNDIEGARSSSSSSNVIRSRRKLREPTPDVDVENY", "length": 288, "header": "tr|Q7JRH2-1|A0A0B4JCU3_DROME Computationally mapped isoform of Receptor expression enhancing protein A, isoform I OS=Drosophila melanogaster OX=7227 GN=ReepA PE=1 SV=1 CANONICAL=A0A0B4JCU3-1" }, "locus": { "chromosome": "2R", "start_pos": 22929534, "end_pos": 22925581, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0302768", "url": "https://www.ensembl.org/id/FBtr0302768" }, { "database": "Ensembl Peptide", "id": "FBpp0291908", "url": "https://www.ensembl.org/id/FBpp0291908" } ] } }, { "isoform_ac": "Q8SX60-1", "url": "", "sequence": { "sequence": "MRPIYQQEPPLFYQRPANLRRLRHPPGTVYGRSYSLEDQPEDVIPVYPKFIYAPQQQQQQQRAPYPLYQLGDSLSSLDSDFPENEYAGAYIVEDRVPLANAPTPKVVQNLNALGRMLELLQRCPLPCLSFNTACICSLIVIFLAPRTCAQSLLFPAFRLFCGTLYPAYASYKAVRTKDVKEYVKWMMYWIVFAFFTCIETFTDIFISWLPFYYEVKVALVFWLLSPATKGSSTLYRKFVHPMLTRHEQEIDEYVNQAKERGYSAVLQLGSKGVNYATNVLMQTAIKTYALTTAPSGHGRGLQNSHSADELYRGQDTMDSTENWLPRASSLSSIESYTETIYEPRTETKRLVIREVSEEAEFDDDPLGDAGAARLRDMPVRKAQPRRAASTAKAAGKRGQKHNDIEGARSSSSSSNVIRSRRKLREPTPDVDVENY", "length": 435, "header": "tr|Q8SX60-1|A0A0B4JCU3_DROME Computationally mapped isoform of Receptor expression enhancing protein A, isoform I OS=Drosophila melanogaster OX=7227 GN=ReepA PE=1 SV=1 CANONICAL=A0A0B4JCU3-1" }, "locus": { "chromosome": "2R", "start_pos": 22929534, "end_pos": 22926626, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0302766", "url": "https://www.ensembl.org/id/FBtr0302766" }, { "database": "Ensembl Peptide", "id": "FBpp0291906", "url": "https://www.ensembl.org/id/FBpp0291906" } ] } }, { "isoform_ac": "Q9W1X3-1", "url": "", "sequence": { "sequence": "MHRTQDELDDVMMSSMTSSAVVMRSTATGARLLRPRNQTPVGRSGSGTRHSTGMYFTEVDVTAKNAGDFNYNIRSQDDISSGYSSAEPVSGLSRTSSMTNASKARAKSKRNELLEEMRDEVYLDNQLYFQGVQRKSSVPEAEELKIVESSESIQSQELEKVLKEENIDAEDEAFFETLPLIEEHINEVVANYGRDEKLLPQERKHNSIEEEQFEDALFEEPQKCVSDEVDAKNIEEILTDRSQNQTPNGSAETTDSGTPSQNKPYVHPPIDPFLLVLSASASAPDPFMPERPRPMSPREMRETLEEIKHSFRAQLEAEPSVSASPSPSLRPKANHGKGRAPPPPLPPKKHSLSPQPDAISQTSTGSVERKSGIGQLFKNIKANVLRNKANPSQQQPEDEQLAAKETQI", "length": 408, "header": "tr|Q9W1X3-1|A0A0B4JCU3_DROME Computationally mapped isoform of Receptor expression enhancing protein A, isoform I OS=Drosophila melanogaster OX=7227 GN=ReepA PE=1 SV=2 CANONICAL=A0A0B4JCU3-1" }, "locus": { "chromosome": "2R", "start_pos": 22931276, "end_pos": 22929865, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0302772", "url": "https://www.ensembl.org/id/FBtr0302772" }, { "database": "Ensembl Peptide", "id": "FBpp0291912", "url": "https://www.ensembl.org/id/FBpp0291912" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dme:Dmel_CG42678", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+dme:Dmel_CG42678", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "endoplasmic reticulum tubular network organization", "id": "GO:0071786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071786", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4JCU3", "url": "https://www.uniprot.org/uniprot/A0A0B4JCU3" } ], "pmid": "" }, { "name": "response to endoplasmic reticulum stress", "id": "GO:0034976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034976", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4JCU3", "url": "https://www.uniprot.org/uniprot/A0A0B4JCU3" } ], "pmid": "" }, { "name": "endoplasmic reticulum organization", "id": "GO:0007029", "url": 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"endoplasmic reticulum tubular network", "id": "GO:0071782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071782", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4JCU3", "url": "https://www.uniprot.org/uniprot/A0A0B4JCU3" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4JCU3", "url": "https://www.uniprot.org/uniprot/A0A0B4JCU3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A0B4JCU3", "url": "https://www.uniprot.org/uniprot/A0A0B4JCU3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 345, "end_pos": 347, "annotation": "n_glycosylation_sequon" }, { "start_pos": 408, "end_pos": 410, "annotation": "n_glycosylation_sequon" }, { 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