{
    "uniprot_canonical_ac": "A0A096MKC4-1",
    "uniprot_ac": "A0A096MKC4",
    "uniprot_id": "A0A096MKC4_RAT",
    "mass": {
        "chemical_mass": 87018.0,
        "monoisotopic_mass": 87018.0
    },
    "refseq": {},
    "gene_names": [
        {
            "name": "Tmc1",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A096MKC4",
            "id": "A0A096MKC4"
        }
    ],
    "protein_names": [
        {
            "name": "Transmembrane channel-like protein",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "A0A096MKC4"
        }
    ],
    "function": [],
    "disease": [
        {
            "disease_id": "DOID:0110520",
            "recommended_name": {
                "id": "DOID:0110520",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0110520",
                "name": "autosomal recessive nonsyndromic deafness 7",
                "description": "An autosomal recessive nonsyndromic deafness that is characterized by prelingual onset with severe to profound, stable hearing loss and has_material_basis_in mutation in the TMC1 gene on chromosome 9q21."
            },
            "synonyms": [
                {
                    "id": "DOID:0110520",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0110520",
                    "name": "DFNB11",
                    "description": ""
                },
                {
                    "id": "DOID:0110520",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0110520",
                    "name": "DFNB7",
                    "description": ""
                },
                {
                    "id": "DOID:0110520",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0110520",
                    "name": "autosomal recessive deafness 7",
                    "description": ""
                },
                {
                    "id": "MONDO:0010967",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010967",
                    "name": "autosomal recessive nonsyndromic hearing loss 7",
                    "description": "Any autosomal recessive nonsyndromic deafness in which the cause of the disease is a mutation in the TMC1 gene."
                },
                {
                    "id": "MONDO:0010967",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010967",
                    "name": "DFNB11",
                    "description": ""
                },
                {
                    "id": "MONDO:0010967",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010967",
                    "name": "DFNB7",
                    "description": ""
                },
                {
                    "id": "MONDO:0010967",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010967",
                    "name": "TMC1 autosomal recessive nonsyndromic deafness",
                    "description": ""
                },
                {
                    "id": "MONDO:0010967",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010967",
                    "name": "autosomal recessive deafness 7",
                    "description": ""
                },
                {
                    "id": "MONDO:0010967",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010967",
                    "name": "autosomal recessive nonsyndromic deafness 7",
                    "description": ""
                },
                {
                    "id": "MONDO:0010967",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010967",
                    "name": "autosomal recessive nonsyndromic deafness caused by mutation in TMC1",
                    "description": ""
                },
                {
                    "id": "MONDO:0010967",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010967",
                    "name": "autosomal recessive nonsyndromic deafness type 7",
                    "description": ""
                },
                {
                    "id": "MONDO:0010967",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010967",
                    "name": "deafness, autosomal recessive 11",
                    "description": ""
                },
                {
                    "id": "MONDO:0010967",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010967",
                    "name": "deafness, autosomal recessive 7",
                    "description": ""
                },
                {
                    "id": "MONDO:0010967",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010967",
                    "name": "deafness, autosomal recessive type 7",
                    "description": ""
                },
                {
                    "id": "MIM:600974",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/600974",
                    "name": "Deafness, autosomal recessive, 7",
                    "description": "Deafness, autosomal recessive, 7"
                }
            ],
            "evidence": [
                {
                    "id": "0110520",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0110520"
                }
            ]
        },
        {
            "disease_id": "DOID:0110563",
            "recommended_name": {
                "id": "DOID:0110563",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0110563",
                "name": "autosomal dominant nonsyndromic deafness 36",
                "description": "An autosomal dominant nonsyndromic deafness that is characterized by postlingual onset with flat or gently downsloping audioprofiles and has_material_basis_in mutation in the TMC1 gene on chromosome 9q21."
            },
            "synonyms": [
                {
                    "id": "DOID:0110563",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0110563",
                    "name": "DFNA36",
                    "description": ""
                },
                {
                    "id": "DOID:0110563",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0110563",
                    "name": "autosomal dominant deafness 36",
                    "description": ""
                },
                {
                    "id": "MONDO:0011708",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011708",
                    "name": "autosomal dominant nonsyndromic hearing loss 36",
                    "description": "Any autosomal dominant nonsyndromic deafness in which the cause of the disease is a mutation in the TMC1 gene."
                },
                {
                    "id": "MONDO:0011708",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011708",
                    "name": "DFNA36",
                    "description": ""
                },
                {
                    "id": "MONDO:0011708",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011708",
                    "name": "TMC1 autosomal dominant nonsyndromic deafness",
                    "description": ""
                },
                {
                    "id": "MONDO:0011708",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011708",
                    "name": "autosomal dominant deafness 36",
                    "description": ""
                },
                {
                    "id": "MONDO:0011708",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011708",
                    "name": "autosomal dominant nonsyndromic deafness 36",
                    "description": ""
                },
                {
                    "id": "MONDO:0011708",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011708",
                    "name": "autosomal dominant nonsyndromic deafness caused by mutation in TMC1",
                    "description": ""
                },
                {
                    "id": "MONDO:0011708",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011708",
                    "name": "autosomal dominant nonsyndromic deafness type 36",
                    "description": ""
                },
                {
                    "id": "MONDO:0011708",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011708",
                    "name": "deafness, autosomal dominant 36",
                    "description": ""
                },
                {
                    "id": "MONDO:0011708",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0011708",
                    "name": "deafness, autosomal dominant type 36",
                    "description": ""
                },
                {
                    "id": "MIM:606705",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/606705",
                    "name": "Deafness, autosomal dominant, 36",
                    "description": "Deafness, autosomal dominant, 36"
                }
            ],
            "evidence": [
                {
                    "id": "0110563",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0110563"
                }
            ]
        },
        {
            "disease_id": "DOID:10003",
            "recommended_name": {
                "id": "DOID:10003",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:10003",
                "name": "sensorineural hearing loss",
                "description": "An inner ear disease that is characterized by hearing loss resulting from damage to the cochlea, auditory nerve and/or brainstem."
            },
            "synonyms": [
                {
                    "id": "DOID:10003",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10003",
                    "name": "High Frequency Hearing Loss",
                    "description": ""
                },
                {
                    "id": "DOID:10003",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10003",
                    "name": "High frequency deafness",
                    "description": ""
                },
                {
                    "id": "DOID:10003",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10003",
                    "name": "Perceptive deafness",
                    "description": ""
                },
                {
                    "id": "DOID:10003",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10003",
                    "name": "Perceptive hearing loss",
                    "description": ""
                },
                {
                    "id": "DOID:10003",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10003",
                    "name": "Perceptive hearing loss or deafness",
                    "description": ""
                },
                {
                    "id": "DOID:10003",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10003",
                    "name": "Sensorineural Deafness",
                    "description": ""
                },
                {
                    "id": "DOID:10003",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10003",
                    "name": "Sensory hearing loss",
                    "description": ""
                },
                {
                    "id": "DOID:10003",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10003",
                    "name": "central hearing loss",
                    "description": ""
                },
                {
                    "id": "DOID:10003",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10003",
                    "name": "high-frequency hearing loss",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "10003",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:10003"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A096MKC4",
                    "url": "https://www.uniprot.org/uniprot/A0A096MKC4"
                }
            ],
            "common_name": "Rat"
        }
    ],
    "gene": [
        {
            "name": "Tmc1",
            "url": "https://www.uniprot.org/uniprot/A0A096MKC4",
            "locus": {
                "chromosome": "1",
                "start_pos": 218276417,
                "end_pos": 218445955,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSRNOG00000051262",
                        "url": "https://www.ensembl.org/id/ENSRNOG00000051262"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSRNOG00000051262",
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000051262",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "361739",
            "url": "https://www.ncbi.nlm.nih.gov/gene/361739",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR012496",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR012496",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR038900",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR038900",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "rno:361739",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:361739",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "RNKPWKM",
            "url": "https://omabrowser.org/oma/group/RNKPWKM/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR23302",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23302",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR23302:SF18",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23302:SF18",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF07810",
            "url": "http://pfam.xfam.org/family/PF07810",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "1308682",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1308682",
            "database": "RGD",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "A0A096MKC4",
            "url": "https://www.uniprot.org/uniprot/A0A096MKC4",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A096MKC4-1",
            "url": "https://www.uniprot.org/uniprot/A0A096MKC4-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A0G2KB87",
            "url": "https://www.uniprot.org/uniprot/A0A0G2KB87",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A0G2KB87-1",
            "url": "https://www.uniprot.org/uniprot/A0A0G2KB87-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I6GL27",
            "url": "https://www.uniprot.org/uniprot/A0A8I6GL27",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I6GL27-1",
            "url": "https://www.uniprot.org/uniprot/A0A8I6GL27-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MLQIQVEGKEDDTDASSSEEEEEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKAREKERRRRLRRGAEEEEEIDEEELERLKALLDENRQMIATVKCKPWKMEKKIEVLKEAKKFVSENEGALGKGKGKKWFAFKMMMAKKWAKFLRDFENFKAACVPWENKIKAIESQFGSSVASYFLFLRWMYGVNMVLFILTFSLIMLPEYLWGLPYGSLPRKTVPRAEEASAANFGVLYDFNGLAQYSVLFYGYYDNKRTIGWLNFRLPLSYFLVGIMCIGYSFLVVLKAMTKNIGDDGGGDDNTFNFSWKVFCSWDYLIGNPETADNKFNSITMNFKEAIIEERAAQVEENIHLIRFLRFLANFFVFLTLGASGYLIFWAVKRSQEFAQQDPDTLGWWEKNEMNMVMSLLGMFCPTLFDLFAELEDYHPLIALKWLLGRIFALLLGNLYVFILALMDEINNKIEEEKLVKANITLWEANMIKAYNESLSGNTTGPPFFVHPADVPRGPCWETMVGQEFVRLTVSDVLTTYVTILIGDFLRACFVRFCNYCWCWDLEYGYPSYTEFDISGNVLALIFNQGMIWMGSFFAPSLPGINILRLHTSMYFQCWAVMCCNVPEARVFKASRSNNFYLGMLLLILFLSTMPVLYMIVSLPPSFDCGPFSGKNRMFEVIGETLEHDFPSWMAKILRQLSNPGLVIAVILVMVLTIYYLNATAKGQKAANLDLKKKMKQQALENKMRNKKMAAARAAAAAGGQ",
        "length": 755,
        "header": "tr|A0A096MKC4-1|A0A096MKC4_RAT Isoform 1 of Transmembrane channel-like protein  OS=Rattus norvegicus OX=10116 GN=Tmc1 PE=3 SV=2 CANONICAL=A0A096MKC4-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A096MKC4-1",
            "url": "",
            "sequence": {
                "sequence": "MLQIQVEGKEDDTDASSSEEEEEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKAREKERRRRLRRGAEEEEEIDEEELERLKALLDENRQMIATVKCKPWKMEKKIEVLKEAKKFVSENEGALGKGKGKKWFAFKMMMAKKWAKFLRDFENFKAACVPWENKIKAIESQFGSSVASYFLFLRWMYGVNMVLFILTFSLIMLPEYLWGLPYGSLPRKTVPRAEEASAANFGVLYDFNGLAQYSVLFYGYYDNKRTIGWLNFRLPLSYFLVGIMCIGYSFLVVLKAMTKNIGDDGGGDDNTFNFSWKVFCSWDYLIGNPETADNKFNSITMNFKEAIIEERAAQVEENIHLIRFLRFLANFFVFLTLGASGYLIFWAVKRSQEFAQQDPDTLGWWEKNEMNMVMSLLGMFCPTLFDLFAELEDYHPLIALKWLLGRIFALLLGNLYVFILALMDEINNKIEEEKLVKANITLWEANMIKAYNESLSGNTTGPPFFVHPADVPRGPCWETMVGQEFVRLTVSDVLTTYVTILIGDFLRACFVRFCNYCWCWDLEYGYPSYTEFDISGNVLALIFNQGMIWMGSFFAPSLPGINILRLHTSMYFQCWAVMCCNVPEARVFKASRSNNFYLGMLLLILFLSTMPVLYMIVSLPPSFDCGPFSGKNRMFEVIGETLEHDFPSWMAKILRQLSNPGLVIAVILVMVLTIYYLNATAKGQKAANLDLKKKMKQQALENKMRNKKMAAARAAAAAGGQ",
                "length": 755,
                "header": "tr|A0A096MKC4-1|A0A096MKC4_RAT Isoform 1 of Transmembrane channel-like protein  OS=Rattus norvegicus OX=10116 GN=Tmc1 PE=3 SV=2 CANONICAL=A0A096MKC4-1"
            },
            "locus": {
                "chromosome": "1",
                "start_pos": 218432874,
                "end_pos": 218276858,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000076393.2",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000076393.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000068461.2",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000068461.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A0G2KB87-1",
            "url": "",
            "sequence": {
                "sequence": "MIATVKCKPWKMEKKIEVLKEAKKFVSENEGALGKGKGKKWFAFKMMMAKKWAKFLRDFENFKAACVPWENKIKAIESQFGSSVASYFLFLRWMYGVNMVLFILTFSLIMLPEYLWGLPYGSLPRKTVPRAEEASAANFGVLYDFNGLAQYSVLFYGYYDNKRTIGWLNFRLPLSYFLVGIMCIGYSFLVVLKAMTKNIGDDGGGDDNTFNFSWKVFCSWDYLIGNPETADNKFNSITMNFKEAIIEERAAQVEENIHLIRFLRFLANFFVFLTLGASGYLIFWAVKRSQEFAQQDPDTLGWWEKNEMNMVMSLLGMFCPTLFDLFAELEDYHPLIALKWLLGRIFALLLGNLYVFILALMDEINNKIEEEKLVKANITLWEANMIKAYNESLSGNTTGPPFFVHPADVPRGPCWETMVGQEFVRLTVSDVLTTYVTILIGDFLRACFVRFCNYCWCWDLEYGYPSYTEFDISGNVLALIFNQGMIWMGSFFAPSLPGINILRLHTSMYFQCWAVMCCNVPEARVFKASRSNNFYLGMLLLILFLSTMPVLYMIVSLPPSFDCGPFSGKNRMFEVIGETLEHDFPSWMAKILRQLSNPGLVIAVILVMVLTIYYLNATAKGQKAANLDLKKKMKQQALENKMRNKKMAAARAAAAAGGQ",
                "length": 659,
                "header": "tr|A0A0G2KB87-1|A0A0G2KB87_RAT Computationally mapped isoform of Transmembrane channel-like protein  OS=Rattus norvegicus OX=10116 GN=Tmc1 PE=3 SV=2 CANONICAL=A0A096MKC4-1"
            },
            "locus": {
                "chromosome": "1",
                "start_pos": 218386478,
                "end_pos": 218276858,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000077601.2",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000077601.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000075695.2",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000075695.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A8I6GL27-1",
            "url": "",
            "sequence": {
                "sequence": "MQQIPDALYSSPIACYEPSYTEFDISGNVLALIFNQGMIWMGSFFAPSLPGINILRLHTSMYFQCWAVMCCNVPEARVFKASRSNNFYLGMLLLILFLSTMPVLYMIVSLPPSFDCGPFSGKNRMFEVIGETLEHDFPSWMAKILRQLSNPGLVIAVILVMVLTIYYLNATAKGQKAANLDLKKKMKQQALENKMRNKKMAAARAAAAAGGQ",
                "length": 212,
                "header": "tr|A0A8I6GL27-1|A0A8I6GL27_RAT Computationally mapped isoform of Transmembrane channel-like protein  OS=Rattus norvegicus OX=10116 GN=Tmc1 PE=3 SV=1 CANONICAL=A0A096MKC4-1"
            },
            "locus": {
                "chromosome": "1",
                "start_pos": 218303130,
                "end_pos": 218276858,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000106339.1",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000106339.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000095251.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000095251.1"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [
        {
            "id": "rno:361739",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:361739",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q8R4P5-1",
            "protein_name": "Transmembrane channel-like protein 1",
            "gene_name": "Tmc1",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MLQIQVEEKEEDTEESSSEEEEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKAREKERRRRLRRGAEEEEEIDEEELERLKALLDENRQMIATVKCKPWKMEKKIEVLKEAKKFVSENEGALGKGKGKKWFAFKMMMAKKWAKFLRDFENFKAACVPWENKIKAIESQFGSSVASYFLFLRWMYGVNMVLFVLTFSLIMLPEYLWGLPYGSLPRKTVPRAEEASAANFGVLYDFNGLAQYSVLFYGYYDNKRTIGWLNFRLPLSYFLVGIMCIGYSFLVVLKAMTKNIGDDGGGDDNTFNFSWKVFCSWDYLIGNPETADNKFNSITMNFKEAIIEERAAQVEENIHLIRFLRFLANFFVFLTLGASGYLIFWAVKRSQEFAQQDPDTLGWWEKNEMNMVMSLLGMFCPTLFDLFAELEDYHPLIALKWLLGRIFALLLGNLYVFILALMDEINNKIEEEKLVKANITLWEANMIKAYNESLSGLSGNTTGAPFFVHPADVPRGPCWETMVGQEFVRLTVSDVLTTYVTILIGDFLRACFVRFCNYCWCWDLEYGYPSYTEFDISGNVLALIFNQGMIWMGSFFAPSLPGINILRLHTSMYFQCWAVMCCNVPEARVFKASRSNNFYLGMLLLILFLSTMPVLYMIVSLPPSFDCGPFSGKNRMFEVIGETLEHDFPSWMAKILRQLSNPGLVIAVILVMVLTIYYLNATAKGQKAANLDLKKKMKQQALENKMRNKKMAAARAAAAAGGQ",
                "length": 757
            },
            "evidence": [
                {
                    "id": "45230970",
                    "url": "http://www.informatics.jax.org/homology/45230970",
                    "database": "MGI"
                }
            ],
            "common_name": "Mouse"
        },
        {
            "uniprot_canonical_ac": "Q8TDI8-1",
            "protein_name": "Transmembrane channel-like protein 1",
            "gene_name": "TMC1",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MSPKKVQIKVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKAREKERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVLKEAKKFVSENEGALGKGKGKRWFAFKMMMAKKWAKFLRDFENFKAACVPWENKIKAIESQFGSSVASYFLFLRWMYGVNMVLFILTFSLIMLPEYLWGLPYGSLPRKTVPRAEEASAANFGVLYDFNGLAQYSVLFYGYYDNKRTIGWMNFRLPLSYFLVGIMCIGYSFLVVLKAMTKNIGDDGGGDDNTFNFSWKVFTSWDYLIGNPETADNKFNSITMNFKEAITEEKAAQVEENVHLIRFLRFLANFFVFLTLGGSGYLIFWAVKRSQEFAQQDPDTLGWWEKNEMNMVMSLLGMFCPTLFDLFAELEDYHPLIALKWLLGRIFALLLGNLYVFILALMDEINNKIEEEKLVKANITLWEANMIKAYNASFSENSTGPPFFVHPADVPRGPCWETMVGQEFVRLTVSDVLTTYVTILIGDFLRACFVRFCNYCWCWDLEYGYPSYTEFDISGNVLALIFNQGMIWMGSFFAPSLPGINILRLHTSMYFQCWAVMCCNVPEARVFKASRSNNFYLGMLLLILFLSTMPVLYMIVSLPPSFDCGPFSGKNRMFEVIGETLEHDFPSWMAKILRQLSNPGLVIAVILVMVLAIYYLNATAKGQKAANLDLKKKMKMQALENKMRNKKMAAARAAAAAGRQ",
                "length": 760
            },
            "evidence": [
                {
                    "id": "45230970",
                    "url": "http://www.informatics.jax.org/homology/45230970",
                    "database": "MGI"
                }
            ],
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Biological Process",
                "total": 6,
                "go_terms": [
                    {
                        "name": "vestibular reflex",
                        "id": "GO:0060005",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060005",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A096MKC4",
                                "url": "https://www.uniprot.org/uniprot/A0A096MKC4"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "detection of mechanical stimulus involved in sensory perception of sound",
                        "id": "GO:0050910",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050910",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A096MKC4",
                                "url": "https://www.uniprot.org/uniprot/A0A096MKC4"
                            }
                        ],
                        "pmid": ""
                    },
                    {
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                        "id": "GO:0007605",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007605",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A096MKC4",
                                "url": "https://www.uniprot.org/uniprot/A0A096MKC4"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "calcium ion transmembrane transport",
                        "id": "GO:0070588",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070588",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A096MKC4",
                                "url": "https://www.uniprot.org/uniprot/A0A096MKC4"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "regulation of calcium ion transmembrane transport",
                        "id": "GO:1903169",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903169",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A096MKC4",
                                "url": "https://www.uniprot.org/uniprot/A0A096MKC4"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "auditory receptor cell development",
                        "id": "GO:0060117",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060117",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A096MKC4",
                                "url": "https://www.uniprot.org/uniprot/A0A096MKC4"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 3,
                "go_terms": [
                    {
                        "name": "external side of plasma membrane",
                        "id": "GO:0009897",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A096MKC4",
                                "url": "https://www.uniprot.org/uniprot/A0A096MKC4"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "stereocilium tip",
                        "id": "GO:0032426",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032426",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A096MKC4",
                                "url": "https://www.uniprot.org/uniprot/A0A096MKC4"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "plasma membrane",
                        "id": "GO:0005886",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A096MKC4",
                                "url": "https://www.uniprot.org/uniprot/A0A096MKC4"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 2,
                "go_terms": [
                    {
                        "name": "mechanosensitive monoatomic ion channel activity",
                        "id": "GO:0008381",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008381",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A096MKC4",
                                "url": "https://www.uniprot.org/uniprot/A0A096MKC4"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "voltage-gated calcium channel activity",
                        "id": "GO:0005245",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005245",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A096MKC4",
                                "url": "https://www.uniprot.org/uniprot/A0A096MKC4"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 307,
            "end_pos": 309,
            "annotation": "n_glycosylation_sequon"
        },
        {
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            "end_pos": 475,
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            "end_pos": 714,
            "annotation": "n_glycosylation_sequon"
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    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        },
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
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    ],
    "section_stats": [
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