{
    "uniprot_canonical_ac": "A0A075B734-1",
    "uniprot_ac": "A0A075B734",
    "uniprot_id": "AQP7B_HUMAN",
    "mass": {
        "chemical_mass": 37977.0,
        "monoisotopic_mass": 37977.0
    },
    "refseq": {
        "ac": "XP_005277022",
        "name": "aquaporin-7B isoform X2",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005277022"
    },
    "gene_names": [
        {
            "name": "AQP7B",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A075B734",
            "id": "A0A075B734"
        },
        {
            "name": "AQP7B",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005277022",
            "id": "XP_005277022"
        },
        {
            "name": "bA251O17.3",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A075B734",
            "id": "A0A075B734"
        },
        {
            "name": "hCG_2002847",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A075B734",
            "id": "A0A075B734"
        }
    ],
    "protein_names": [
        {
            "name": "Aquaporin-7B",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "A0A075B734"
        },
        {
            "name": "aquaporin-7B isoform X2",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005277022",
            "id": "XP_005277022"
        },
        {
            "name": "aquaporin-7B isoform X3",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016860957",
            "id": "XP_016860957"
        },
        {
            "name": "aquaporin-7B isoform X4",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016860958",
            "id": "XP_016860958"
        }
    ],
    "function": [],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Homo sapiens",
            "taxid": 9606,
            "evidence": [
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                    "database": "UniProtKB",
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                    "url": "https://www.uniprot.org/uniprot/A0A075B734"
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            ],
            "common_name": "Human"
        }
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        {
            "name": "AQP7B",
            "url": "https://www.uniprot.org/uniprot/A0A075B734",
            "locus": {
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                "start_pos": 94612744,
                "end_pos": 94587101,
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                        "database": "Ensembl Gene",
                        "id": "ENSG00000259916",
                        "url": "https://www.ensembl.org/id/ENSG00000259916"
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                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSG00000259916",
            "url": "https://bgee.org/?page=gene&gene_id=ENSG00000259916",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "cd00333",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00333",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "AQP7B",
            "url": "http://www.genecards.org/cgi-bin/carddisp.pl?gene=AQP7B",
            "database": "GeneCards",
            "categories": [
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                "Gene Annotation"
            ]
        },
        {
            "id": "100509620",
            "url": "https://www.ncbi.nlm.nih.gov/gene/100509620",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "53895",
            "url": "https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=53895",
            "database": "HGNC",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "IPR000425",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000425",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR023271",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR023271",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "EWIGVNI",
            "url": "https://omabrowser.org/oma/group/EWIGVNI/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "5490746at2759",
            "url": "http://www.orthodb.org/?query=5490746at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR43829",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43829",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR43829:SF12",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43829:SF12",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00230",
            "url": "http://pfam.xfam.org/family/PF00230",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_A0A075B734",
            "url": "http://purl.obolibrary.org/obo/PR_A0A075B734",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A075B734",
            "url": "https://www.uniprot.org/uniprot/A0A075B734",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A075B734-1",
            "url": "https://www.uniprot.org/uniprot/A0A075B734-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8Q3SI91",
            "url": "https://www.uniprot.org/uniprot/A0A8Q3SI91",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8Q3SI91-1",
            "url": "https://www.uniprot.org/uniprot/A0A8Q3SI91-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8Q3SI93",
            "url": "https://www.uniprot.org/uniprot/A0A8Q3SI93",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8Q3SI93-1",
            "url": "https://www.uniprot.org/uniprot/A0A8Q3SI93-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8Q3SIF9",
            "url": "https://www.uniprot.org/uniprot/A0A8Q3SIF9",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8Q3SIF9-1",
            "url": "https://www.uniprot.org/uniprot/A0A8Q3SIF9-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8Q3SJ69",
            "url": "https://www.uniprot.org/uniprot/A0A8Q3SJ69",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8Q3SJ69-1",
            "url": "https://www.uniprot.org/uniprot/A0A8Q3SJ69-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8Q3WL09",
            "url": "https://www.uniprot.org/uniprot/A0A8Q3WL09",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8Q3WL09-1",
            "url": "https://www.uniprot.org/uniprot/A0A8Q3WL09-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q8WX69",
            "url": "https://www.uniprot.org/uniprot/Q8WX69",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q8WX69-1",
            "url": "https://www.uniprot.org/uniprot/Q8WX69-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
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        "sequence": "MVQASGHRRSTRGSKMVSWSVIAKIQEIWCEEDERKMVREFLAEFMSTYVMMVFGLGSVAHMVLNKTYGSYLGVNLGFGFGVTMGVHVAGRISGAHMNAAVTFTNCALGRVPWRKFPVHVLGQFLGSFLAAATIYICVSAAAILHFSGGELMVTGPFATAGIFATYLPDHMTLWRGFLNEEWLTRMLQLCLFTITDQENNPALPGTHALVISILVVIIRVSHGINTGYAINPSRDPPPSIFTFIAGWGKQVFSDGENWWWVPVVAPLLGASLGGIIYLVFIGSTIPREPLKLEDSVAYEDHGITVLPKMGSHEPMISPLTLISVSLANRSSVHSAPPLHESMALEHF",
        "length": 347,
        "header": "sp|A0A075B734-1|AQP7B_HUMAN Isoform 1 of Aquaporin-7B  OS=Homo sapiens OX=9606 GN=AQP7B PE=3 SV=1 CANONICAL=A0A075B734-1"
    },
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        {
            "isoform_ac": "A0A075B734-1",
            "url": "",
            "sequence": {
                "sequence": "MVQASGHRRSTRGSKMVSWSVIAKIQEIWCEEDERKMVREFLAEFMSTYVMMVFGLGSVAHMVLNKTYGSYLGVNLGFGFGVTMGVHVAGRISGAHMNAAVTFTNCALGRVPWRKFPVHVLGQFLGSFLAAATIYICVSAAAILHFSGGELMVTGPFATAGIFATYLPDHMTLWRGFLNEEWLTRMLQLCLFTITDQENNPALPGTHALVISILVVIIRVSHGINTGYAINPSRDPPPSIFTFIAGWGKQVFSDGENWWWVPVVAPLLGASLGGIIYLVFIGSTIPREPLKLEDSVAYEDHGITVLPKMGSHEPMISPLTLISVSLANRSSVHSAPPLHESMALEHF",
                "length": 347,
                "header": "sp|A0A075B734-1|AQP7B_HUMAN Isoform 1 of Aquaporin-7B  OS=Homo sapiens OX=9606 GN=AQP7B PE=3 SV=1 CANONICAL=A0A075B734-1"
            },
            "locus": {}
        },
        {
            "isoform_ac": "A0A8Q3SI91-1",
            "url": "",
            "sequence": {
                "sequence": "MVQASGHRRSTRGSKMVSWSVIAKIQEIWCEEDERKMVREFLAEFMSTYVMMEWLTRMLQLCLFTITDQENNPALPGTHALVISILVVIIRVSHGINTGYAINPSRDPPPSIFTFIAGWGKQVFSDGENWWWVPVVAPLLGASLGGIIYLVFIGSTIPREPLKLEDSVAYEDHGITVLPKMGSHEPMISPLTLISVSLANRSSVHSAPPLHESMALEHF",
                "length": 219,
                "header": "tr|A0A8Q3SI91-1|A0A8Q3SI91_HUMAN Computationally mapped isoform of Aquaporin 7B  OS=Homo sapiens OX=9606 GN=AQP7B PE=4 SV=1 CANONICAL=A0A075B734-1"
            },
            "locus": {
                "chromosome": "2",
                "start_pos": 94604570,
                "end_pos": 94588522,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENST00000696095.1",
                        "url": "https://www.ensembl.org/id/ENST00000696095.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSP00000512392.1",
                        "url": "https://www.ensembl.org/id/ENSP00000512392.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A8Q3SI93-1",
            "url": "",
            "sequence": {
                "sequence": "MVQASGHRRSTRGSKMVSWSVIAKIQEIWCEEDERKMVREFLAEFMSTYVMMEPT",
                "length": 55,
                "header": "tr|A0A8Q3SI93-1|AQP7B_HUMAN Computationally mapped isoform of Aquaporin-7B  OS=Homo sapiens OX=9606 GN=AQP7B PE=3 SV=1 CANONICAL=A0A075B734-1"
            },
            "locus": {
                "chromosome": "2",
                "start_pos": 94603045,
                "end_pos": 94588522,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENST00000696093.1",
                        "url": "https://www.ensembl.org/id/ENST00000696093.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSP00000512390.1",
                        "url": "https://www.ensembl.org/id/ENSP00000512390.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A8Q3SIF9-1",
            "url": "",
            "sequence": {
                "sequence": "MVQASGHRRSTRGSKMVSWSVIAKIQEIWCEEDERKMVREFLAEFMSTYVMMEWLTRMLQLCLFTITDQENNPALPGTHALVISILVVIIRVSHGINTGYAINPSRDPPPSIFTFIAGWGKQVFRYCPCPGPFL",
                "length": 134,
                "header": "tr|A0A8Q3SIF9-1|A0A8Q3SIF9_HUMAN Computationally mapped isoform of Aquaporin 7B  OS=Homo sapiens OX=9606 GN=AQP7B PE=4 SV=1 CANONICAL=A0A075B734-1"
            },
            "locus": {
                "chromosome": "2",
                "start_pos": 94603957,
                "end_pos": 94588522,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENST00000696092.1",
                        "url": "https://www.ensembl.org/id/ENST00000696092.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSP00000512389.1",
                        "url": "https://www.ensembl.org/id/ENSP00000512389.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A8Q3SJ69-1",
            "url": "",
            "sequence": {
                "sequence": "MVTGPFATAGIFATYLPDHMTLWRGFLNEEWLTRMLQLCLFTITDQENNPALPGTHALVISILVVIIRVSHGINTGYAINPSRDPPPSIFTFIAGWGKQVFSDGENWWWVPVVAPLLGASLGGIIYLVFIGSTIPREPLKLEDSVAYEDHGITVLPKMGSHEPMISPLTLISVSLANRSSVHSAPPLHESMALEHF",
                "length": 196,
                "header": "tr|A0A8Q3SJ69-1|A0A8Q3SJ69_HUMAN Computationally mapped isoform of Aquaporin 7B  OS=Homo sapiens OX=9606 GN=AQP7B PE=3 SV=1 CANONICAL=A0A075B734-1"
            },
            "locus": {
                "chromosome": "2",
                "start_pos": 94604570,
                "end_pos": 94603415,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENST00000696099.1",
                        "url": "https://www.ensembl.org/id/ENST00000696099.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSP00000512395.1",
                        "url": "https://www.ensembl.org/id/ENSP00000512395.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A8Q3WL09-1",
            "url": "",
            "sequence": {
                "sequence": "MVSWSVIAKIQEIWCEEDERKMVREFLAEFMSTYVMMEWLTRMLQLCLFTITDQENNPALPGTHALVISILVVIIRVSHGINTGYAINPSRDPPPSIFTFIAGWGKQVFSDGENWWWVPVVAPLLGASLGGIIYLVFIGSTIPREPLKLEDSVAYEDHGITVLPKMGSHEPMISPLTLISVSLANRSSVHSAPPLHESMALEHF",
                "length": 204,
                "header": "tr|A0A8Q3WL09-1|A0A8Q3WL09_HUMAN Computationally mapped isoform of Aquaporin 7B  OS=Homo sapiens OX=9606 GN=AQP7B PE=4 SV=1 CANONICAL=A0A075B734-1"
            },
            "locus": {
                "chromosome": "2",
                "start_pos": 94604570,
                "end_pos": 94594763,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENST00000696100.1",
                        "url": "https://www.ensembl.org/id/ENST00000696100.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSP00000512396.1",
                        "url": "https://www.ensembl.org/id/ENSP00000512396.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q8WX69-1",
            "url": "",
            "sequence": {
                "sequence": "MVQASGHRRSTRGSKMVSWSVIAKIQEIWCEEDERKMVREFLAEFMSTYVMMVFGLGSVAHMVLNKTYGSYLGVNLGFGFGVTMGVHVAGRISGAHMNAAVTFTNCALGRVPWRKFPVHVLGQFLGSFLAAATIYSLFYTAILHFSGGELMVTGPFATAGIFATYLPDHMTLWRGFLNEEWLTRMLQLCLFTITDQENNPALPGTHALVISILVVIIRVSHGINTGYAINPSRDPPPSIFTFIAGWGKQVFSDGENWWWVPVVAPLLGASLGGIIYLVFIGSTIPREPLKLEDSVAYEDHGITVLPKMGSHEPMISPLTLISVSLANRSSVHSAPPLHESMALEHF",
                "length": 346,
                "header": "tr|Q8WX69-1|Q8WX69_HUMAN Computationally mapped isoform of BA251O17.3 (Similar to aquaporin 7)  OS=Homo sapiens OX=9606 GN=AQP7B PE=3 SV=1 CANONICAL=A0A075B734-1"
            },
            "locus": {
                "chromosome": "2",
                "start_pos": 94604570,
                "end_pos": 94588522,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENST00000561882.2",
                        "url": "https://www.ensembl.org/id/ENST00000561882.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSP00000456868.2",
                        "url": "https://www.ensembl.org/id/ENSP00000456868.2"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [],
    "orthologs": [],
    "go_annotation": {
        "categories": [
            {
                "name": "Cellular Component",
                "total": 3,
                "go_terms": [
                    {
                        "name": "membrane",
                        "id": "GO:0016020",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A075B734",
                                "url": "https://www.uniprot.org/uniprot/A0A075B734"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "plasma membrane",
                        "id": "GO:0005886",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A075B734",
                                "url": "https://www.uniprot.org/uniprot/A0A075B734"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "basolateral plasma membrane",
                        "id": "GO:0016323",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A075B734",
                                "url": "https://www.uniprot.org/uniprot/A0A075B734"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 3,
                "go_terms": [
                    {
                        "name": "water channel activity",
                        "id": "GO:0015250",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015250",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A075B734",
                                "url": "https://www.uniprot.org/uniprot/A0A075B734"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "glycerol channel activity",
                        "id": "GO:0015254",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015254",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A075B734",
                                "url": "https://www.uniprot.org/uniprot/A0A075B734"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "urea transmembrane transporter activity",
                        "id": "GO:0015204",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015204",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A075B734",
                                "url": "https://www.uniprot.org/uniprot/A0A075B734"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 2,
                "go_terms": [
                    {
                        "name": "water transport",
                        "id": "GO:0006833",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006833",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A075B734",
                                "url": "https://www.uniprot.org/uniprot/A0A075B734"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "glycerol transmembrane transport",
                        "id": "GO:0015793",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015793",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A075B734",
                                "url": "https://www.uniprot.org/uniprot/A0A075B734"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
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