{ "uniprot_canonical_ac": "Q9Z2H2-1", "uniprot_ac": "Q9Z2H2", "uniprot_id": "RGS6_MOUSE", "mass": { "chemical_mass": 54531.0, "monoisotopic_mass": 54531.0 }, "refseq": { "ac": "NP_001297407", "name": "regulator of G-protein signaling 6 isoform 1", "summary": "This gene encodes a member of the RGS (regulator of G protein signaling) family of proteins, which are defined by the presence of a RGS domain that confers the GTPase-activating activity of these proteins toward certain G alpha subunits. This protein also belongs to a subfamily of RGS proteins characterized by the presence of DEP (Dishevelled, Egl-10, and Pleckstrin) and GGL (G-protein gamma like)domains, the latter a G beta 5-interacting domain. The RGS proteins negatively regulate G protein signaling, and may modulate neuronal, cardiovascular, lymphocytic activities, and cancer risk. Mice lacking this gene exhibit decreased heart rate. Alternative splicing results in multiple transcript variants, however, the full-length nature of some of these variants is not known. [provided by RefSeq, Sep 2015].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001297407" }, "gene_names": [ { "name": "Rgs6", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/Q9Z2H2", "id": "Q9Z2H2" }, { "name": "Rgs6", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001297407", "id": "NP_001297407" } ], "protein_names": [ { "name": "Regulator of G-protein signaling 6", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "Q9Z2H2" }, { "name": "RGS6", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q9Z2H2" }, { "name": "regulator of G-protein signaling 6 isoform 1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001297407", "id": "NP_001297407" }, { "name": "regulator of G-protein signaling 6 isoform 2", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001268990", "id": "NP_001268990" } ], "function": [ { "annotation": "GPCR-dependent biasing of GIRK channel signaling dynamics by RGS6 in mouse sinoatrial nodal cells.", "evidence": [ { "database": "RefSeq", "id": "NP_001268990", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001268990" }, { "database": "PubMed", "id": "32513692", "url": "https://glygen.org/publication/PubMed/32513692" }, { "database": "RefSeq", "id": "NP_001297407", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001297407" } ] }, { "annotation": "RGS6 Drives Spinal Cord Injury by Inhibiting AMPK Pathway in Mice. Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_001268990", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001268990" }, { "database": "PubMed", "id": "35510037", "url": "https://glygen.org/publication/PubMed/35510037" }, { "database": "RefSeq", "id": "NP_001297407", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001297407" } ] }, { "annotation": "RGS6 Mediates Effects of Voluntary Running on Adult Hippocampal Neurogenesis. Erratum:[Cell Rep. 2020 Aug 25;32(8):108114. PMID: 32846117]", "evidence": [ { "database": "RefSeq", "id": "NP_001268990", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001268990" }, { "database": "PubMed", "id": "32755589", "url": "https://glygen.org/publication/PubMed/32755589" }, { "database": "RefSeq", "id": "NP_001297407", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001297407" } ] }, { "annotation": "RGS6 negatively regulates inhibitory G protein signaling in dopamine neurons and positively regulates binge-like alcohol consumption in mice.", "evidence": [ { "database": "RefSeq", "id": "NP_001268990", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001268990" }, { "database": "PubMed", "id": "36929333", "url": "https://glygen.org/publication/PubMed/36929333" }, { "database": "RefSeq", "id": "NP_001297407", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001297407" } ] }, { "annotation": "Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. The RGS6/GNB5 dimer enhances GNAO1 GTPase activity.", "evidence": [ { "database": "UniProtKB", "id": "Q9Z2H2", "url": "https://www.uniprot.org/uniprot/Q9Z2H2#function" }, { "database": "UniProtKB", "id": "P49758", "url": "https://www.uniprot.org/uniprot/P49758#function" } ] }, { "annotation": "Rgs16 and Rgs8 are likely to control aspects of islet progenitor cell activation, differentiation and beta-cell expansion in embryos and metabolically stressed adults.", "evidence": [ { "database": "RefSeq", "id": "NP_001268990", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001268990" }, { "database": "PubMed", "id": "20616094", "url": "https://glygen.org/publication/PubMed/20616094" }, { "database": "RefSeq", "id": "NP_001297407", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001297407" } ] }, { "annotation": "This gene encodes a member of the RGS (regulator of G protein signaling) family of proteins, which are defined by the presence of a RGS domain that confers the GTPase-activating activity of these proteins toward certain G alpha subunits. This protein also belongs to a subfamily of RGS proteins characterized by the presence of DEP (Dishevelled, Egl-10, and Pleckstrin) and GGL (G-protein gamma like)domains, the latter a G beta 5-interacting domain. The RGS proteins negatively regulate G protein signaling, and may modulate neuronal, cardiovascular, lymphocytic activities, and cancer risk. Mice lacking this gene exhibit decreased heart rate. Alternative splicing results in multiple transcript variants, however, the full-length nature of some of these variants is not known. [provided by RefSeq, Sep 2015].", "evidence": [ { "database": "RefSeq", "id": "NP_001268990", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001268990" }, { "database": "RefSeq", "id": "NP_001297407", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001297407" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9Z2H2", "url": "https://www.uniprot.org/uniprot/Q9Z2H2" } ], "common_name": "Mouse" } ], "gene": [ { "name": "Rgs6", "url": "https://www.uniprot.org/uniprot/Q9Z2H2", "locus": { "chromosome": "12", "start_pos": 83208830, "end_pos": 82635066, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSMUSG00000021219", "url": "https://www.ensembl.org/id/ENSMUSG00000021219" } ] } } ], "crossref": [ { "id": "ENSMUSG00000021219", "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000021219", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00068", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00068", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04450", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04450", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08737", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08737", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "50779", "url": "https://www.ncbi.nlm.nih.gov/gene/50779", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9Z2H2", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9Z2H2*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR000591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015898", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015898", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016137", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016137", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024066", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024066", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036284", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036284", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036305", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036305", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037956", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037956", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040759", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040759", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044926", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044926", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047016", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047016", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047017", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047017", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "mmu:50779", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:50779", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "1354730", "url": "http://www.informatics.jax.org/marker/MGI:1354730", "database": "MGI", "categories": [ "Organism-specific" ] }, { "id": "Q9Z2H2", "url": "https://oglcnac.org/atlas/detail/Q9Z2H2", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "Q9Z2H2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9Z2H2", "database": "O-GlcNAc Database", "categories": [ "Glycoproteomics" ] }, { "id": "PNMIVFR", "url": "https://omabrowser.org/oma/group/PNMIVFR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "22856at2759", "url": "http://www.orthodb.org/?query=22856at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45746", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45746", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45746:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45746:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00610", "url": "http://pfam.xfam.org/family/PF00610", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF00615", "url": "http://pfam.xfam.org/family/PF00615", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF00631", "url": "http://pfam.xfam.org/family/PF00631", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF18148", "url": "http://pfam.xfam.org/family/PF18148", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PR_Q9Z2H2", "url": "http://purl.obolibrary.org/obo/PR_Q9Z2H2", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-MMU-418594", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-418594", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "R-MMU-6814122", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-6814122", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "NP_001268990", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001268990", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A087WNZ9", "url": "https://www.uniprot.org/uniprot/A0A087WNZ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A087WNZ9-1", "url": "https://www.uniprot.org/uniprot/A0A087WNZ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A087WPC4", "url": "https://www.uniprot.org/uniprot/A0A087WPC4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A087WPC4-1", "url": "https://www.uniprot.org/uniprot/A0A087WPC4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A087WPD1", "url": "https://www.uniprot.org/uniprot/A0A087WPD1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A087WPD1-1", "url": "https://www.uniprot.org/uniprot/A0A087WPD1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A087WPW1", "url": "https://www.uniprot.org/uniprot/A0A087WPW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A087WPW1-1", "url": "https://www.uniprot.org/uniprot/A0A087WPW1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A087WQG6", "url": "https://www.uniprot.org/uniprot/A0A087WQG6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A087WQG6-1", "url": "https://www.uniprot.org/uniprot/A0A087WQG6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A087WRP8", "url": "https://www.uniprot.org/uniprot/A0A087WRP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A087WRP8-1", "url": "https://www.uniprot.org/uniprot/A0A087WRP8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A087WSH2", "url": "https://www.uniprot.org/uniprot/A0A087WSH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A087WSH2-1", "url": "https://www.uniprot.org/uniprot/A0A087WSH2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A087WSJ9", "url": "https://www.uniprot.org/uniprot/A0A087WSJ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A087WSJ9-1", "url": "https://www.uniprot.org/uniprot/A0A087WSJ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0J9YTS6", "url": "https://www.uniprot.org/uniprot/A0A0J9YTS6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0J9YTS6-1", "url": "https://www.uniprot.org/uniprot/A0A0J9YTS6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0J9YU74", "url": "https://www.uniprot.org/uniprot/A0A0J9YU74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0J9YU74-1", "url": "https://www.uniprot.org/uniprot/A0A0J9YU74-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0J9YUD1", "url": "https://www.uniprot.org/uniprot/A0A0J9YUD1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0J9YUD1-1", "url": "https://www.uniprot.org/uniprot/A0A0J9YUD1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0J9YUE4", "url": "https://www.uniprot.org/uniprot/A0A0J9YUE4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0J9YUE4-1", "url": "https://www.uniprot.org/uniprot/A0A0J9YUE4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0J9YUY2", "url": "https://www.uniprot.org/uniprot/A0A0J9YUY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0J9YUY2-1", "url": "https://www.uniprot.org/uniprot/A0A0J9YUY2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6WDS8", "url": "https://www.uniprot.org/uniprot/F6WDS8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F6WDS8-1", "url": "https://www.uniprot.org/uniprot/F6WDS8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q3UTM5", "url": "https://www.uniprot.org/uniprot/Q3UTM5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q3UTM5-1", "url": "https://www.uniprot.org/uniprot/Q3UTM5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9Z2H2", "url": "https://www.uniprot.org/uniprot/Q9Z2H2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9Z2H2-1", "url": "https://www.uniprot.org/uniprot/Q9Z2H2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAQGSGDQRAVGIADPEESSPNMIVYCKIEDIITKMQDDKTGGVPIRTVKSFLSKIPSVVTGTDIVQWLMKNLSIEDPVEAIHLGSLIAAQGYIFPISDHVLTMKDDGTFYRFQAPYFWPSNCWEPENTDYAIYLCKRTMQNKARLELADYEAENLARLQRAFARKWEFIFMQAEAQVKIDRKKDKTERKILDSQERAFWDVHRPVPGCVNTTEMDIRKCRRLKNPQKVKKSVYGVTDETQSQSPVHIPSQPIRKTTKDDIRKQITFLNAQIDRHCLKMSKVAESLIAYTEQYVEYDPFITPAEPSNPWISDDITLWDIEMSKEPSQQRVKRWGFSFDEILKDQVGRDQFLRFLESEFSSENLRFWLSVQDLKKQPLQDVAKRVEEIWQEFLAPGAPSAINLDSHSYEITSQNVKDGGRYTFEDAQEHIYKLMKSDSYARFLRSNAYQDLLLAKKKGKSLAGKRLTGLMQSS", "length": 472, "header": "sp|Q9Z2H2-1|RGS6_MOUSE Isoform 1 of Regulator of G-protein signaling 6 OS=Mus musculus OX=10090 GN=Rgs6 PE=1 SV=2 CANONICAL=Q9Z2H2-1" }, "isoforms": [ { "isoform_ac": "A0A087WNZ9-1", "url": "", "sequence": { "sequence": "MAQGSGDQRAVGIADPEESSPNMIVYCKIEDIITKMQDDKTGGVPIRTVKSFLSKIPSVVTGTDIVQWLMKNLSIEDPVEAIHLGSLIAAQGYIFPISDHVLTMKDDGTFYRFQAPYFWPSNCWEPENTDYAIYLCKRTMQNKARLELADYEAENLARLQRAFARKWEFIFMQAEAQVKIDRKKDKTERKILDSQERAFWDVHRPVPGCVNTTEMDIRKCRRLKNPQKVKKSVYGVTDETQSQSPVHIPSQPIRKTTKDDIRKQITFLNAQIDRHCLKMSKVAESLIAYTEQYVEYDPFITPAEPSNPWISDDITLWDIEMSKEPSQQRVKRWGFSFDEILKDQVGRDQFLRFLESEFSSENLRFWLSVQDLKKQPLQDVAKRVEEIWQEFLAPGAPSAINLDSHSYEITSQNVKDGGRYTFEDAQEHIYKLMKSDSYARFLRSNAYQDLLLAKKKPESEQGRRTSLEKFTRSVGKSLAGKRLTGLMQSS", "length": 490, "header": "tr|A0A087WNZ9-1|A0A087WNZ9_MOUSE Computationally mapped isoform of Regulator of G-protein signaling 6 OS=Mus musculus OX=10090 GN=Rgs6 PE=1 SV=1 CANONICAL=Q9Z2H2-1" }, "locus": { "chromosome": "12", "start_pos": 83204742, "end_pos": 82698603, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000185665.7", "url": "https://www.ensembl.org/id/ENSMUST00000185665.7" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000139566.2", "url": "https://www.ensembl.org/id/ENSMUSP00000139566.2" } ] } }, { "isoform_ac": "A0A087WPC4-1", "url": "", "sequence": { "sequence": "MAQGSGDQRAVGIADPEESSPNMIVYCKIEDIITKMQDDKTGGVPIRTVKSFLSKIPSVVTGTDIVQWLMKNLSIEDPVEAIHLGSLIAAQGYIFPISDHVLTMKDDGTFYRFQAPYFWPSNCWEPENTDYAIYLCKRTMQNKARLELADYEAENLARLQRAFARKWEFIFMQAEAQVKIDRKKDKTERKILDSQERAFWDVHRPVPGCVNTTEMDIRKCRRLKNPQKVKKSVYGVTDETQSQSPVHIPSQPIRKTTKDDIRKQITFLNAQIDRHCLKMSKVAESLIAYTEQYVEYDPFITPAEPSNPWISDDITLWDIEMSKEPSQQRVKRWGFSFDEILKDQVGRDQFLRFLESEFSSENLRFWLSVQDLKKQPLQDVAKRVEEIWQEFLAPGAPSAINLDSHSYEITSQNVKDGGRYTFEDAQEHIYKLMKSDSYARFLRSNAYQDLLLAKKKPESEQGRRTSLEKFTRSVCLQLLFQGWNCKKKKKKKEQAAPSAEGS", "length": 502, "header": "tr|A0A087WPC4-1|A0A087WPC4_MOUSE Computationally mapped isoform of Regulator of G-protein signaling 6 OS=Mus musculus OX=10090 GN=Rgs6 PE=1 SV=1 CANONICAL=Q9Z2H2-1" }, "locus": { "chromosome": "12", "start_pos": 83184448, "end_pos": 82698603, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000191352.7", "url": "https://www.ensembl.org/id/ENSMUST00000191352.7" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000139718.2", "url": "https://www.ensembl.org/id/ENSMUSP00000139718.2" } ] } }, { "isoform_ac": "A0A087WPD1-1", "url": "", "sequence": { "sequence": "MAQGSGDQRAVGIADPEESSPNMIVYCKIEDIITKMQDDKTGGVPIRTVKSFLSKIPSVVTGTDIVQWLMKNLSIEDPVEAIHLGSLIAAQGYIFPISDHVLTMKDDGTFYRFQAPYFWPSNCWEPENTDYAIYLCKRTMQNKARLELADYEAENLARLQRAFARKWEFIFMQAEAQVKIDRKKDKTERKILDSQERAFWDVHRPVPGCVNTTEMDIRKCRRLKNPQKVKKSVYGVTDETQSQSPVHIPSQPIRKTTKDDIRKQITFLNAQIDRHCLKMSKVAESLIAYTEQYVEYDPFITPAEPSNPWISDDITLWDIEMSKEPSQQRVKRWGFSFDEILKDQVGRDQFLRFLESEFSSENLRFWLSVQDLKKQPLQDVAKRVEEIWQEFLAPGAPSAINLDSHSYEITSQNVKDGGRYTFEDAQEHIYKLMKSDSYARFLRSNAYQDLLLAKKKPESEQGRRTSLEKFTRSVLLFQGWNCKKKKKKKEQAAPSAEGSQLKAQP", "length": 505, "header": "tr|A0A087WPD1-1|A0A087WPD1_MOUSE Computationally mapped isoform of Regulator of G-protein signaling 6 OS=Mus musculus OX=10090 GN=Rgs6 PE=1 SV=1 CANONICAL=Q9Z2H2-1" }, "locus": { "chromosome": "12", "start_pos": 83184466, "end_pos": 82698603, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000191107.7", "url": "https://www.ensembl.org/id/ENSMUST00000191107.7" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000139725.2", "url": "https://www.ensembl.org/id/ENSMUSP00000139725.2" } ] } }, { "isoform_ac": "A0A087WPW1-1", "url": "", "sequence": { "sequence": "MAQGSGDQRAVGIADPEESSPNMIVYCKIEDIITKMQDDKTGGVPIRTVKSFLSKIPSVVTGTDIVQWLMKNLSIEDPVEAIHLGSLIAAQGYIFPISDHVLTMKDDGTFYRFQAPYFWPSNCWEPENTDYAIYLCKRTMQNKARLELADYEAENLARLQRAFARKWEFIFMQAEAQVKIDRKKDKTERKILDSQERAFWDVHRPVPGCVNTTEMDIRKCRRLKNPQKVKKSVYGVTDETQSQSPVHIPSQPIRKTTKDDIRKQITFLNAQIDRHCLKMSKVAESKEPSQQRVKRWGFSFDEILKDQVGRDQFLRFLESEFSSENLRFWLSVQDLKKQPLQDVAKRVEEIWQEFLAPGAPSAINLDSHSYEITSQNVKDGGRYTFEDAQEHIYKLMKSDSYARFLRSNAYQDLLLAKKKPESEQGRRTSLEKFTRSVGKSLAGKRLTGLMQSS", "length": 453, "header": "tr|A0A087WPW1-1|A0A087WPW1_MOUSE Computationally mapped isoform of Regulator of G-protein signaling 6 OS=Mus musculus OX=10090 GN=Rgs6 PE=1 SV=1 CANONICAL=Q9Z2H2-1" }, "locus": { "chromosome": "12", "start_pos": 83204742, "end_pos": 82698603, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000185674.7", "url": "https://www.ensembl.org/id/ENSMUST00000185674.7" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000139940.2", "url": "https://www.ensembl.org/id/ENSMUSP00000139940.2" } ] } }, { "isoform_ac": "A0A087WQG6-1", "url": "", "sequence": { "sequence": "MAQGSGDQRAVGIADPEESSPNMIVYCKIEDIITKMQDDKTGGVPIRTVKSFLSKIPSVVTGTDIVQWLMKNLSIEDPVEAIHLGSLIAAQGYIFPISDHVLTMKDDGTFYRFQAPYFWPSNCWEPENTDYAIYLCKRTMQNKARLELADYEAENLARLQRAFARKWEFIFMQAEAQVKIDRKKDKTERKILDSQERAFWDVHRPVPGCVNTTEMDIRKCRRLKNPQKVKKSVYGVTDETQSQSPVHIPSQPIRKTTKDDIRKQITFLNAQIDRHCLKMSKVAESLIAYTEQYVEYDPFITPAEPSNPWISDDITLWDIEMSKEPSQQRVKRWGFSFDEILKDQVGRDQFLRFLESEFSSENLRFWLSVQDLKKQPLQDVAKRVEEIWQEFLAPGAPSAINLDSHSYEITSQNVKDGGRYTFEDAQEHIYKLMKSDSYARFLRSNAYQDLLLAKKKKVSKVVGLP", "length": 465, "header": "tr|A0A087WQG6-1|A0A087WQG6_MOUSE Computationally mapped isoform of Regulator of G-protein signaling 6 OS=Mus musculus OX=10090 GN=Rgs6 PE=1 SV=2 CANONICAL=Q9Z2H2-1" }, "locus": { "chromosome": "12", "start_pos": 83184190, "end_pos": 82698603, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000186081.7", "url": "https://www.ensembl.org/id/ENSMUST00000186081.7" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000140188.3", "url": "https://www.ensembl.org/id/ENSMUSP00000140188.3" } ] } }, { "isoform_ac": "A0A087WRP8-1", "url": "", "sequence": { "sequence": "MAQGSGDQRAVGIADPEESSPNMIVYCKIEDIITKMQDDKTGGVPIRTVKSFLSKIPSVVTGTDIVQWLMKNLSIEDPVEAIHLGSLIAAQGYIFPISDHVLTMKDDGTFYRFQAPYFWPSNCWEPENTDYAIYLCKRTMQNKARLELADYEAENLARLQRAFARKWEFIFMQAEAQVKIDRKKDKTERKILDSQERAFWDVHRPVPGCVNTTEMDIRKCRRLKNPQKVKKSVYGVTDETQSQSPVHIPSQPIRKTTKDDIRKQITFLNAQIDRHCLKMSKVAESLIAYTEQYVEYDPFITPAEPSNPWISDDITLWDIEMSKEPSQQRVKRWGFSFDEILKDQVGRDQFLRFLESEFSSENLRFWLSVQDLKKQPLQDVAKRVEEIWQEFLAPGAPSAINLDSHSYEITSQNVKDGGRYTFEDAQEHIYKLMKSDSYARFLRSNAYQDLLLAKKKPESEQGRRTSLEKFTRSVGWNCKKKKKKKEQAAPSAEGS", "length": 495, "header": "tr|A0A087WRP8-1|A0A087WRP8_MOUSE Computationally mapped isoform of Regulator of G-protein signaling 6 OS=Mus musculus OX=10090 GN=Rgs6 PE=1 SV=1 CANONICAL=Q9Z2H2-1" }, "locus": { "chromosome": "12", "start_pos": 83184448, "end_pos": 82698603, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000191311.7", "url": "https://www.ensembl.org/id/ENSMUST00000191311.7" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000140723.2", "url": "https://www.ensembl.org/id/ENSMUSP00000140723.2" } ] } }, { "isoform_ac": "A0A087WSH2-1", "url": "", "sequence": { "sequence": "MQDDKTGGVPIRTVKSFLSKIPSVVTGTDIVQWLMKNLSIEDPVEAIHLGSLIAAQGYIFPISDHVLTMKDDGTFYRFQAPYFWPSNCWEPENTDYAIYLCKRTMQNKARLELADYEAENLARLQRAFARKWEFIFMQAEAQVKIDRKKDKTERKILDSQERAFWDVHRPVPGCVNTTEMDIRKCRRLKNPQKVKKSVYGVTDETQSQSPVHIPSQPIRKTTKDDIRKQITFLNAQIDRHCLKMSKVAESLIAYTEQYVEYDPFITPAEPSNPWISDDITLWDIEMSKEPSQQRVKRWGFSFDEILKDQVGRDQFLRFLESEFSSENLRFWLSVQDLKKQPLQDVAKRVEEIWQEFLAPGAPSAINLDSHSYEITSQNVKDGGRYTFEDAQEHIYKLMKSDSYARFLRSNAYQDLLLAKKKGKSLAGKRLTGLMQSS", "length": 437, "header": "tr|A0A087WSH2-1|A0A087WSH2_MOUSE Computationally mapped isoform of Regulator of G-protein signaling 6 OS=Mus musculus OX=10090 GN=Rgs6 PE=1 SV=4 CANONICAL=Q9Z2H2-1" }, "locus": { "chromosome": "12", "start_pos": 83204742, "end_pos": 83032090, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000186848.5", "url": "https://www.ensembl.org/id/ENSMUST00000186848.5" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000141044.3", "url": "https://www.ensembl.org/id/ENSMUSP00000141044.3" } ] } }, { "isoform_ac": "A0A087WSJ9-1", "url": "", "sequence": { "sequence": "MAQGSGDQRAVGIADPEESSPNMIVYCKIEDIITKMQDDKTGGVPIRTVKSFLSKIPSVVTGTDIVQWLMKNLSIEDPVEAIHLGSLIAAQGYIFPISDHVLTMKDDGTFYRFQAPYFWPSNCWEPENTDYAIYLCKRTMQNKARLELADYEAENLARLQRAFARKWEFIFMQAEAQVKIDRKKDKTERKILDSQERAFWDVHRPVPGCVNTTEMDIRKCRRLKNPQKVKKSVYGVTDETQSQSPVHIPSQPIRKTTKDDIRKQITFLNAQIDRHCLKMSKVAESKEPSQQRVKRWGFSFDEILKDQVGRDQFLRFLESEFSSENLRFWLSVQDLKKQPLQDVAKRVEEIWQEFLAPGAPSAINLDSHSYEITSQNVKDGGRYTFEDAQEHIYKLMKSDSYARFLRSNAYQDLLLAKKKGKSLAGKRLTGLMQSS", "length": 435, "header": "tr|A0A087WSJ9-1|A0A087WSJ9_MOUSE Computationally mapped isoform of Regulator of G-protein signaling 6 OS=Mus musculus OX=10090 GN=Rgs6 PE=1 SV=1 CANONICAL=Q9Z2H2-1" }, "locus": { "chromosome": "12", "start_pos": 83204742, "end_pos": 82698603, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000186323.7", "url": "https://www.ensembl.org/id/ENSMUST00000186323.7" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000141079.2", "url": "https://www.ensembl.org/id/ENSMUSP00000141079.2" } ] } }, { "isoform_ac": "A0A0J9YTS6-1", "url": "", "sequence": { "sequence": "XWGFSFDEILKDQVGRDQFLRFLESEFSSENLRFWLSVQDLKKQPLQDVAKRVEEIWQEFLAPGAPSAINLDSHSYEITSQNVKDGGRYTFEDAQEHIYKLMKSDSYARFLRSNAYQDLLLAKKKPESEQGRRTSLEKFTRSVCCWRRVRMAAAFHPRGGFLPAVGKVAGGQAPYGPDAVLLTAPTPGPGPGPTEDPGRRRSTSNDRASLRGDLVTVKEKE", "length": 221, "header": "tr|A0A0J9YTS6-1|RGS6_MOUSE Computationally mapped isoform of Regulator of G-protein signaling 6 OS=Mus musculus OX=10090 GN=Rgs6 PE=1 SV=1 CANONICAL=Q9Z2H2-1" }, "locus": { "chromosome": "12", "start_pos": 83204862, "end_pos": 83153561, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000201767.2", "url": "https://www.ensembl.org/id/ENSMUST00000201767.2" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000143829.2", "url": "https://www.ensembl.org/id/ENSMUSP00000143829.2" } ] } }, { "isoform_ac": "A0A0J9YU74-1", "url": "", "sequence": { "sequence": "MAQGSGDQRAVGIADPEESSPNMIVYCKIEDIITKMQDDKTGGVPIRTVKSFLSKIPSVVTGTDIVQWLMKN", "length": 72, "header": "tr|A0A0J9YU74-1|A0A0J9YU74_MOUSE Computationally mapped isoform of Regulator of G-protein signaling 6 OS=Mus musculus OX=10090 GN=Rgs6 PE=1 SV=3 CANONICAL=Q9Z2H2-1" }, "locus": { "chromosome": "12", "start_pos": 83094364, "end_pos": 82698603, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000201602.4", "url": "https://www.ensembl.org/id/ENSMUST00000201602.4" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000144044.2", "url": "https://www.ensembl.org/id/ENSMUSP00000144044.2" } ] } }, { "isoform_ac": "A0A0J9YUD1-1", "url": "", "sequence": { "sequence": "MAQGSGDQRAVGIADPEESSPNMIVYCKIEDIITKMQDDKTGGVPIRTVKSFLSKIPSVVTGTDIVQWLMKNLSIEDPVEAIHLGSLIAAQGYIFPISDHVLTMKDDGT", "length": 109, "header": "tr|A0A0J9YUD1-1|A0A0J9YUD1_MOUSE Computationally mapped isoform of Regulator of G-protein signaling 6 OS=Mus musculus OX=10090 GN=Rgs6 PE=1 SV=1 CANONICAL=Q9Z2H2-1" }, "locus": { "chromosome": "12", "start_pos": 83098144, "end_pos": 82698603, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000200861.4", "url": "https://www.ensembl.org/id/ENSMUST00000200861.4" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000144118.2", "url": "https://www.ensembl.org/id/ENSMUSP00000144118.2" } ] } }, { "isoform_ac": "A0A0J9YUE4-1", "url": "", "sequence": { "sequence": "MAQGSGDQRAVGIADPEESSPNMIVYCKIEDIITKMQDDKTGGVPIRTVKSFLSKIPSVVTGTDIVQWLMKNLSIEDPVEAIHLGSLIAAQGYIFPISDHVLTMKDDGTFYRFQAPYFWPSNCWEPENTDYAIYLCKRTMQNKARLELADYEAENLARLQRAFARKWEFIFMQAEAQVKIDRKKDKTERKILDSQERAFWDVHRPV", "length": 206, "header": "tr|A0A0J9YUE4-1|A0A0J9YUE4_MOUSE Computationally mapped isoform of Regulator of G-protein signaling 6 OS=Mus musculus OX=10090 GN=Rgs6 PE=1 SV=1 CANONICAL=Q9Z2H2-1" }, "locus": { "chromosome": "12", "start_pos": 83112809, "end_pos": 82698603, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000201271.4", "url": "https://www.ensembl.org/id/ENSMUST00000201271.4" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000144139.2", "url": "https://www.ensembl.org/id/ENSMUSP00000144139.2" } ] } }, { "isoform_ac": "A0A0J9YUY2-1", "url": "", "sequence": { "sequence": "MAQGSGDQRAVGIADPEESSPNMIVYCKIEDIITKMQDDKTGGVPIRTVKSFLSKIPSVVTGTDIVQWLMKNLSIEDPVEAIHLGSLI", "length": 88, "header": "tr|A0A0J9YUY2-1|A0A0J9YUY2_MOUSE Computationally mapped isoform of Regulator of G-protein signaling 6 OS=Mus musculus OX=10090 GN=Rgs6 PE=1 SV=1 CANONICAL=Q9Z2H2-1" }, "locus": { "chromosome": "12", "start_pos": 83098081, "end_pos": 82698603, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000201861.4", "url": "https://www.ensembl.org/id/ENSMUST00000201861.4" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000144395.2", "url": "https://www.ensembl.org/id/ENSMUSP00000144395.2" } ] } }, { "isoform_ac": "F6WDS8-1", "url": "", "sequence": { "sequence": "MAQGSGDQRAVGIADPEESSPNMIVYCKIEDIITKMQDDKTGGVPIRTVKSFLSKIPSVVTGTDIVQWLMKNLSIEDPVEAIHLGSLIAAQGYIFPISDHVLTMKDDGTFYRFQAPYFWPSNCWEPENTDYAIYLCKRTMQNKARLELADYEAENLARLQRAFARKWEFIFMQAEAQVKIDRKKDKTERKILDSQERAFWDVHRPVPGCVNTTEMDIRKCRRLKNPQKVKKSVYGVTDETQSQSPVHIPSQPIRKTTKDDIRKQITFLNAQIDRHCLKMSKVAESLIAYTEQYVEYDPFITPAEPSNPWISDDITLWDIEMSKEPSQQRVKRWGFSFDEILKDQVGRDQFLRFLESEFSSENLRFWLSVQDLKKQPLQDVAKRVEEIWQEFLAPGAPSAINLDSHSYEITSQNVKDGGRYTFEDAQEHIYKLMKSDSYARFLRSNAYQDLLLAKKK", "length": 456, "header": "tr|F6WDS8-1|F6WDS8_MOUSE Computationally mapped isoform of Regulator of G-protein signaling 6 OS=Mus musculus OX=10090 GN=Rgs6 PE=1 SV=1 CANONICAL=Q9Z2H2-1" }, "locus": { "chromosome": "12", "start_pos": 83180518, "end_pos": 82698603, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000101234.9", "url": "https://www.ensembl.org/id/ENSMUST00000101234.9" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000098793.3", "url": "https://www.ensembl.org/id/ENSMUSP00000098793.3" } ] } }, { "isoform_ac": "Q3UTM5-1", "url": "", "sequence": { "sequence": "MAQGSGDQRAVGIADPEESSPNMIVYCKIEDIITKMQDDKTGGVPIRTVKSFLSKIPSVVTGTDIVQWLMKNLSIEDPVEAIHLGSLIAAQGYIFPISDHVLTMKDDGTFYRFQAPYFWPSNCWEPENTDYAIYLCKRTMQNKARLELADYEAENLARLQRAFARKWEFIFMQAEAQVKIDRKKDKTERKILDSQERAFWDVHRPVPGCVNTTEMDIRKCRRLKNPQKVKKSVYGVTDETQSQSPVHIPSQPIRKTTKDDIRKQITFLNAQIDRHCLKMSKVAESLIAYTEQYVEYDPFITPAEPSNPWISDDITLWDIEMSFDLYMASLCLQWQLAPLLSVSWLWLLEGKTLLPQLVSFISGRSNTS", "length": 368, "header": "tr|Q3UTM5-1|Q3UTM5_MOUSE Computationally mapped isoform of Regulator of G-protein signaling 6 OS=Mus musculus OX=10090 GN=Rgs6 PE=1 SV=1 CANONICAL=Q9Z2H2-1" }, "locus": { "chromosome": "12", "start_pos": 83138948, "end_pos": 82698603, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000161801.8", "url": "https://www.ensembl.org/id/ENSMUST00000161801.8" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000125256.3", "url": "https://www.ensembl.org/id/ENSMUSP00000125256.3" } ] } }, { "isoform_ac": "Q9Z2H2-1", "url": "", "sequence": { "sequence": "MAQGSGDQRAVGIADPEESSPNMIVYCKIEDIITKMQDDKTGGVPIRTVKSFLSKIPSVVTGTDIVQWLMKNLSIEDPVEAIHLGSLIAAQGYIFPISDHVLTMKDDGTFYRFQAPYFWPSNCWEPENTDYAIYLCKRTMQNKARLELADYEAENLARLQRAFARKWEFIFMQAEAQVKIDRKKDKTERKILDSQERAFWDVHRPVPGCVNTTEMDIRKCRRLKNPQKVKKSVYGVTDETQSQSPVHIPSQPIRKTTKDDIRKQITFLNAQIDRHCLKMSKVAESLIAYTEQYVEYDPFITPAEPSNPWISDDITLWDIEMSKEPSQQRVKRWGFSFDEILKDQVGRDQFLRFLESEFSSENLRFWLSVQDLKKQPLQDVAKRVEEIWQEFLAPGAPSAINLDSHSYEITSQNVKDGGRYTFEDAQEHIYKLMKSDSYARFLRSNAYQDLLLAKKKGKSLAGKRLTGLMQSS", "length": 472, "header": "sp|Q9Z2H2-1|RGS6_MOUSE Isoform 1 of Regulator of G-protein signaling 6 OS=Mus musculus OX=10090 GN=Rgs6 PE=1 SV=2 CANONICAL=Q9Z2H2-1" }, "locus": { "chromosome": "12", "start_pos": 83204742, "end_pos": 82698603, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000186458", "url": "https://www.ensembl.org/id/ENSMUST00000186458" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000139735", "url": "https://www.ensembl.org/id/ENSMUSP00000139735" } ] } } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "site_category": "reported_with_glycan", "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "start_pos": 336, "start_aa": "Ser", "end_pos": 336, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser336", "evidence": [ { "id": "Q9Z2H2", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9Z2H2" }, { "id": "30059200", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/30059200" }, { "id": "Q9Z2H2", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q9Z2H2" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_reported_with_glycan" ], "publication": [ { "title": "R7BP, a novel neuronal protein interacting with RGS proteins of the R7 family.", "journal": "J. Biol. Chem.", "date": "2005", "authors": "Martemyanov KA, Yoo PJ, Skiba NP, Arshavsky VY", "evidence": [ { "database": "UniProtKB", "id": "Q9Z2H2", "url": "https://www.uniprot.org/uniprot/Q9Z2H2" } ], "reference": [ { "type": "PubMed", "id": "15632198", "url": "https://glygen.org/publication/PubMed/15632198" } ] }, { "title": "Palmitoylation regulates plasma membrane-nuclear shuttling of R7BP, a novel membrane anchor for the RGS7 family.", "journal": "J. Cell Biol.", "date": "2005", "authors": "Drenan RM, Doupnik CA, Boyle MP, Muglia LJ, Huettner JE, Linder ME, Blumer KJ", "evidence": [ { "database": "UniProtKB", "id": "Q9Z2H2", "url": "https://www.uniprot.org/uniprot/Q9Z2H2" } ], "reference": [ { "type": "PubMed", "id": "15897264", "url": "https://glygen.org/publication/PubMed/15897264" } ] }, { "title": "Rgs16 and Rgs8 in embryonic endocrine pancreas and mouse models of diabetes.", "journal": "Disease models & mechanisms", "date": "2010", "authors": "Villasenor A, Wang ZV, Rivera LB, Ocal O, Asterholm IW, Scherer PE, Brekken RA, Cleaver O, Wilkie TM", "evidence": [ { "database": "RefSeq", "id": "NP_001268990", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001268990" }, { "database": "RefSeq", "id": "NP_001297407", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001297407" } ], "reference": [ { "type": "PubMed", "id": "20616094", "url": "https://glygen.org/publication/PubMed/20616094" } ] }, { "title": "Quantitative Profiling of 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