{ "uniprot_canonical_ac": "Q9WVJ2-1", "uniprot_ac": "Q9WVJ2", "uniprot_id": "PSD13_MOUSE", "mass": { "chemical_mass": 42809.0, "monoisotopic_mass": 42809.0 }, "refseq": { "ac": "NP_036005", "name": "26S proteasome non-ATPase regulatory subunit 13", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_036005" }, "gene_names": [ { "name": "Psmd13", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/Q9WVJ2", "id": "Q9WVJ2" }, { "name": "Psmd13", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_036005", "id": "NP_036005" }, { "name": "S11", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_036005", "id": "NP_036005" } ], "protein_names": [ { "name": "26S proteasome non-ATPase regulatory subunit 13", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "Q9WVJ2" }, { "name": "26S proteasome non-ATPase regulatory subunit 13", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_036005", "id": "NP_036005" }, { "name": "26S proteasome regulatory subunit RPN9", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q9WVJ2" }, { "name": "26S proteasome regulatory subunit S11; 26S proteasome regulatory subunit p40.5; 26S proteasome regulatory subunit RPN9; 26S proteasome subunit p40.5", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_036005", "id": "NP_036005" }, { "name": "26S proteasome regulatory subunit S11", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q9WVJ2" }, { "name": "26S proteasome regulatory subunit p40.5", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q9WVJ2" } ], "function": [ { "annotation": "Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. 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"Protein Classification" ] }, { "id": "R-MMU-9020702", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9020702", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "R-MMU-9755511", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9755511", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "R-MMU-9762114", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9762114", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "R-MMU-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-983168", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "NP_036005", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_036005", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E9PY93", "url": "https://www.uniprot.org/uniprot/E9PY93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E9PY93-1", "url": "https://www.uniprot.org/uniprot/E9PY93-1", 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"tr|E9Q0U1-1|PSD13_MOUSE Computationally mapped isoform of 26S proteasome non-ATPase regulatory subunit 13 OS=Mus musculus OX=10090 GN=Psmd13 PE=1 SV=1 CANONICAL=Q9WVJ2-1" }, "locus": { "chromosome": "7", "start_pos": 140478143, "end_pos": 140462385, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000164681.8", "url": "https://www.ensembl.org/id/ENSMUST00000164681.8" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000132405.2", "url": "https://www.ensembl.org/id/ENSMUSP00000132405.2" } ] } }, { "isoform_ac": "E9Q5I9-1", "url": "", "sequence": { "sequence": "MKDVPAFLQQSQSSGPGQAAVWHRLEELYTKKLWHQLTLEVLDFVQDPCFAQGDGLIKLYENFISEFEHRVNPLSLVEIILHVVRQMTDPNVALTFLEKTREKVKSSDEAVILCKTAIGALKLNIGDLQATKETIEDVEEMLNNLPGVTSVHSRFYDLSSKYYQTIGNHASYYKDALRFLGCVDIKDLPVSEQQERAFTLGLAGLLGEGVFNFGELLMHPVLESLRDTDRQWLIDTLYAFNSGAVDRFQTLKCAWGQQPDLAANEAQLLRKIQLLCLMEVELLVMKALSVGLVRGSIDEVDKRVHMTWVQPRVLDLQQIKGMKDRLELWCTDVKSMEMLVEHQAQDILT", "length": 349, "header": "tr|E9Q5I9-1|E9Q5I9_MOUSE Computationally mapped isoform of 26S proteasome non-ATPase regulatory subunit 13 OS=Mus musculus OX=10090 GN=Psmd13 PE=1 SV=1 CANONICAL=Q9WVJ2-1" }, "locus": { "chromosome": "7", "start_pos": 140478198, "end_pos": 140462385, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000163610.9", "url": "https://www.ensembl.org/id/ENSMUST00000163610.9" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000130580.2", "url": "https://www.ensembl.org/id/ENSMUSP00000130580.2" } ] } }, { "isoform_ac": "F6PXS6-1", "url": "", "sequence": { "sequence": "XKIQLLCLMEMTFTRPANHRQLTFEEIAKSAKITVNKVELLVMKALSVGLVRGSIDEVMRKGTNGNGDRVVSTQLHLSGLCPVWSECCSNKCLGIV", "length": 96, "header": "tr|F6PXS6-1|F6PXS6_MOUSE Computationally mapped isoform of 26S proteasome non-ATPase regulatory subunit 13 OS=Mus musculus OX=10090 GN=Psmd13 PE=1 SV=1 CANONICAL=Q9WVJ2-1" }, "locus": { "chromosome": "7", "start_pos": 140478556, "end_pos": 140474428, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000165539.2", "url": "https://www.ensembl.org/id/ENSMUST00000165539.2" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000130256.2", "url": "https://www.ensembl.org/id/ENSMUSP00000130256.2" } ] } }, { "isoform_ac": "F6ZQQ3-1", "url": "", "sequence": { "sequence": "XTIGNHASYYKDALRFLGCVDIKDLPVSEQQERAFTLGLAGLLGEGVFNFGELLMHPVLESLRDTDRQWLIDTLYAFNSGAVDRFQTLKCAWGQQPDLAANEAQLLRKIQLLCLMEMTFTRPANHRQLTFEEIAKSAKITVNKVELLVMKALSVGLVRGSIDEVDKRVHMTWVQPRVLDLQQVRGLGPCPLRVYQCCPSFMWTEAI", "length": 206, "header": "tr|F6ZQQ3-1|PSD13_MOUSE Computationally mapped isoform of 26S proteasome non-ATPase regulatory subunit 13 OS=Mus musculus OX=10090 GN=Psmd13 PE=1 SV=1 CANONICAL=Q9WVJ2-1" }, "locus": { "chromosome": "7", "start_pos": 140477711, "end_pos": 140469313, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000130462.8", "url": "https://www.ensembl.org/id/ENSMUST00000130462.8" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000126160.2", "url": "https://www.ensembl.org/id/ENSMUSP00000126160.2" } ] } }, { "isoform_ac": "Q9WVJ2-1", "url": "", "sequence": { "sequence": "MKDVPAFLQQSQSSGPGQAAVWHRLEELYTKKLWHQLTLEVLDFVQDPCFAQGDGLIKLYENFISEFEHRVNPLSLVEIILHVVRQMTDPNVALTFLEKTREKVKSSDEAVILCKTAIGALKLNIGDLQATKETIEDVEEMLNNLPGVTSVHSRFYDLSSKYYQTIGNHASYYKDALRFLGCVDIKDLPVSEQQERAFTLGLAGLLGEGVFNFGELLMHPVLESLRDTDRQWLIDTLYAFNSGAVDRFQTLKCAWGQQPDLAANEAQLLRKIQLLCLMEMTFTRPANHRQLTFEEIAKSAKITVNKVELLVMKALSVGLVRGSIDEVDKRVHMTWVQPRVLDLQQIKGMKDRLELWCTDVKSMEMLVEHQAQDILT", "length": 376, "header": "sp|Q9WVJ2-1|PSD13_MOUSE Isoform 1 of 26S proteasome non-ATPase regulatory subunit 13 OS=Mus musculus OX=10090 GN=Psmd13 PE=1 SV=1 CANONICAL=Q9WVJ2-1" }, "locus": { "chromosome": "7", "start_pos": 140478198, "end_pos": 140462385, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000026560", "url": "https://www.ensembl.org/id/ENSMUST00000026560" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000026560", "url": "https://www.ensembl.org/id/ENSMUSP00000026560" } ] } } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "site_category": "reported_with_glycan", "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "evidence": [ { "id": "Q9WVJ2", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9WVJ2" }, { "id": "33300544", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/33300544" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_reported_with_glycan" ], "publication": [ { "title": "Mapping the murine cardiac 26S proteasome complexes.", "journal": "Circ. Res.", "date": "2006", "authors": "Gomes AV, Zong C, Edmondson RD, Li X, Stefani E, Zhang J, Jones RC, Thyparambil S, Wang GW, Qiao X, Bardag-Gorce F, Ping P", "evidence": [ { "database": "UniProtKB", "id": "Q9WVJ2", "url": "https://www.uniprot.org/uniprot/Q9WVJ2" } ], "reference": [ { "type": "PubMed", "id": "16857966", "url": "https://glygen.org/publication/PubMed/16857966" } ] }, { "title": "O-GlcNAcylation regulates dopamine neuron function, survival and degeneration in Parkinson disease.", "journal": "Brain : a journal of neurology", "date": "2020", "authors": "Lee BE, Kim HY, Kim HJ, Jeong H, Kim BG, Lee HE, Lee J, Kim HB, Lee SE, Yang YR, Yi EC, Hanover JA, Myung K, Suh PG, Kwon T, Kim JI", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9WVJ2", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9WVJ2" } ], "reference": [ { "type": "PubMed", "id": "33300544", "url": "https://glygen.org/publication/PubMed/33300544" } ] } ], "pathway": [ { "id": "mmu:23997", 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