{ "uniprot_canonical_ac": "Q9W0S9-1", "uniprot_ac": "Q9W0S9", "uniprot_id": "DIP2_DROME", "mass": { "chemical_mass": 194154.0, "monoisotopic_mass": 194154.0 }, "refseq": { "ac": "NP_612019", "name": "DISCO interacting protein 2, isoform A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_612019" }, "gene_names": [ { "name": "DIP2", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/Q9W0S9", "id": "Q9W0S9" }, { "name": "CG7020; Ddip2; Dmel\\CG7020", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001246530", "id": "NP_001246530" }, { "name": "CG7020", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q9W0S9", "id": "Q9W0S9" }, { "name": "DIP2", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001246530", "id": "NP_001246530" }, { "name": "Ddip2", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q9W0S9", "id": "Q9W0S9" }, { "name": "Dmel\\CG7020", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q9W0S9", "id": "Q9W0S9" }, { "name": "Dmel_CG7020", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q9W0S9", "id": "Q9W0S9" } ], "protein_names": [ { "name": "Disco-interacting protein 2", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "Q9W0S9" }, { "name": "CG7020-PA; DIP2-PA", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_612019", "id": "NP_612019" }, { "name": "CG7020-PB; DIP2-PB", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001246530", "id": "NP_001246530" }, { "name": "CG7020-PC; DIP2-PC", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261191", "id": "NP_001261191" }, { "name": "CG7020-PD; DIP2-PD", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261192", "id": "NP_001261192" }, { "name": "CG7020-PE; DIP2-PE", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261193", "id": "NP_001261193" }, { "name": "DISCO interacting protein 2, isoform A", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_612019", "id": "NP_612019" }, { "name": "DISCO interacting protein 2, isoform B", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001246530", "id": "NP_001246530" }, { "name": "DISCO interacting protein 2, isoform C", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261191", "id": "NP_001261191" }, { "name": "DISCO interacting protein 2, isoform D", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261192", "id": "NP_001261192" }, { "name": "DISCO interacting protein 2, isoform E", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001261193", "id": "NP_001261193" } ], "function": [ { "annotation": "Required for precise axonal bifurcation in mushroom body neurons by suppressing ectopic bifurcation and regulating the guidance of sister axons (PubMed:28396149, PubMed:27908785). Acts downstream of the serine/threonine-protein kinase Bsk to modulate the direction of axon projection (PubMed:28396149). May play a role in fatty acid metabolism (PubMed:27908785).", "evidence": [ { "database": "UniProtKB", "id": "Q9W0S9", "url": "https://www.uniprot.org/uniprot/Q9W0S9#function" }, { "database": "PubMed", "id": "28396149", "url": "https://glygen.org/publication/PubMed/28396149" }, { "database": "PubMed", "id": "27908785", "url": "https://glygen.org/publication/PubMed/27908785" } ] } ], "disease": [ { "disease_id": "DOID:0060307", "recommended_name": { "id": "DOID:0060307", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0060307", "name": "autosomal dominant intellectual developmental disorder", "description": "A intellectual disability characterized by an autosomal dominant inheritance pattern." }, "synonyms": [ { "id": "DOID:0060307", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0060307", "name": "autosomal dominant mental retardation", "description": "" }, { "id": "DOID:0060307", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0060307", "name": "autosomal dominant non-syndromic mental retardation", "description": "" }, { "id": "MONDO:0007974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007974", "name": "intellectual disability, autosomal dominant 1", "description": "An autosomal dominant condition caused by mutation(s) in the MBD5 gene, encoding methyl-CpG-binding domain protein 5. It is characterized by severe developmental and cognitive delay, short stature, craniofacial dysmorphism, and seizures." }, { "id": "MONDO:0007974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007974", "name": "MBD5 autosomal dominant non-syndromic intellectual disability", "description": "" }, { "id": "MONDO:0007974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007974", "name": "MRD1", "description": "" }, { "id": "MONDO:0007974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007974", "name": "autosomal dominant intellectual disability 1", "description": "" }, { "id": "MONDO:0007974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007974", "name": "autosomal dominant mental retardation 1", "description": "" }, { "id": "MONDO:0007974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007974", "name": "autosomal dominant non-syndromic intellectual disability caused by mutation in MBD5", "description": "" }, { "id": "MONDO:0007974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007974", "name": "intellectual disability, autosomal dominant 1", "description": "" }, { "id": "MONDO:0007974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007974", "name": "intellectual disability, autosomal dominant type 1", "description": "" }, { "id": "MONDO:0007974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007974", "name": "mental retardation, autosomal dominant type 1", "description": "" }, { "id": "MONDO:0007974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007974", "name": "autosomal dominant non-syndromic intellectual disability 1", "description": "" }, { "id": "MONDO:0007974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007974", "name": "chromosome 2Q23.1 deletion syndrome", "description": "" }, { "id": "MONDO:0007974", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007974", "name": "mental retardation, autosomal dominant 1", "description": "" }, { "id": "MIM:156200", "resource": "MIM", "url": "https://www.omim.org/entry/156200", "name": "Intellectual developmental disorder, autosomal dominant 1", "description": "Intellectual developmental disorder, autosomal dominant 1" } ], "evidence": [ { "id": "0060307", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:0060307" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9W0S9", "url": "https://www.uniprot.org/uniprot/Q9W0S9" } ], "common_name": "Fruit fly" } ], "gene": [ { "name": "DIP2", "url": "https://www.uniprot.org/uniprot/Q9W0S9", "locus": { "chromosome": "3L", "start_pos": 250229, "end_pos": 257954, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "FBgn0024806", "url": "https://www.ensembl.org/id/FBgn0024806" } ] } } ], "crossref": [ { "id": "FBgn0024806", "url": "https://bgee.org/?page=gene&gene_id=FBgn0024806", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05905", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05905", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "FBgn0024806", "url": "https://flybase.org/reports/FBgn0024806", "database": "FlyBase", "categories": [ "Organism-specific" ] }, { "id": "252479", "url": "https://www.ncbi.nlm.nih.gov/gene/252479", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q9W0S9", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9W0S9*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR000873", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000873", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010506", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010506", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042099", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042099", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045851", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045851", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG7020", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+dme:Dmel_CG7020", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VEHRYFF", "url": "https://omabrowser.org/oma/group/VEHRYFF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "3994129at2759", "url": "http://www.orthodb.org/?query=3994129at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22754", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22754", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22754:SF32", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22754:SF32", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00501", "url": "http://pfam.xfam.org/family/PF00501", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF06464", "url": "http://pfam.xfam.org/family/PF06464", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PR_Q9W0S9", "url": "http://purl.obolibrary.org/obo/PR_Q9W0S9", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_612019", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_612019", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "M9NDW1", "url": "https://www.uniprot.org/uniprot/M9NDW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "M9NDW1-1", "url": "https://www.uniprot.org/uniprot/M9NDW1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "M9PBG6", "url": "https://www.uniprot.org/uniprot/M9PBG6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "M9PBG6-1", "url": "https://www.uniprot.org/uniprot/M9PBG6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "M9PDH5", "url": "https://www.uniprot.org/uniprot/M9PDH5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "M9PDH5-1", "url": "https://www.uniprot.org/uniprot/M9PDH5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "M9PGJ0", "url": "https://www.uniprot.org/uniprot/M9PGJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "M9PGJ0-1", "url": "https://www.uniprot.org/uniprot/M9PGJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W0S9", "url": "https://www.uniprot.org/uniprot/Q9W0S9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9W0S9-1", "url": "https://www.uniprot.org/uniprot/Q9W0S9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEHTASLPGYVREKLAELDLELSEGDITQKGYEKKRAKLLQPFLKKPEGDKVKSTPPPPYYNVKNANNSTNHGNINNDGVIVSSEGYSYVTEVPSLSSSQQRHSKKIDFHQQAAMSLSSAPQSGNAGAPGYENMRPQGGAVGDPGYQNTREPSAFQNQQSTNNSQHRQRRTQRKVTHNEKRYHSEVRQEAVQQALAALKGRPKPSLPMPSKRTSVLNRSPGCNDELDSSTDDESIPEETISPDKEYNYPRDHISNSILPPEPIIKPPIRESSMGSQQHARTDVKQNQITNQKYTAPNSAPERRPPQNLPPLPTSEPLSSDYPPIAYKRENDFSDKAFKQKQYNAPDITQFNNAHRAADRVTRYVNVSQNELNETDANGKWKVSAKIQQLLNTLKRPKRRPLPEFYEDNDIELEIAANTKDPNAPKPEGSTMTPVQGEQLSIPAGLPRTLECALQRYGTNSFKSPMATVLDPNGKVTTTLTYGKLLSRAQKIAHALSTKIFSKGPEQVTLKPGDRVALVYPNNDPLSFITAWYGCMFRGLVPLPIELPLSSSDTPPQQVGFLLSSCGITVALTSEACLKGLPKSTTTGEIAKLKGWPRLQWFVTEHLPKPPKEFNVGNLRADDSAAAYIEYTTDKEGSVMGVTVTRAAMINHCRALTMACHYTEGETIVCVLDFKREVGLWHSVLTSVLNGMHVIFIPYALMKLRPSSWMQLITKHRASCCLVKSRDLHWGLLATKDHKDISLSSLRMLLVADGANPWSLSSCDQFLSVFQAKGLRSDAICPCASSSEVFTVSLRRPGRGSCGFSPSATGRGVLSMAALSHGVVRVDSEDSLTSLTLQDCGQVMPAAQMVVVRSEGPPVLCKTDQVGEICVTSGSTSASYFGLDGMTNSTFKVQPLLEELEQPKDGNGTVNIISKPIGEDFYVRSGLLGFLGPGGLVFVCGSRDGLMTVTGRKHNADDIIATVLAVEPMRFIYRGRIAVFSIKVLRDERVCVIAEQRPDCSEEESFQWMSRVLQAVDSIHQVGIYCLALVPPNHLPKTPLGGIHLCEARRRFLEGSLHPANVLMCPHTCVTNLPKPRELHQGVQTAAKLSSSSGCGITDTGVGPASVMVGNLVQGNRLAEAHGRDVGLAEDCERKPQLITGVLRWRANTSPDHIIFTLLNSKGAIAKTLTCSELHKRAEKIAALLQERGRIEPGDHVALIFPPGLDLLCAFYGCLYLGAIPITIRPPHPQNLNTTLPTVRMIVDVSKSGIVLSIQPIIKLLKSREAATSIDPKTWPPILDIDDNPKRKYAGIATVSFDSSAYLDFSVSTCGRLSGVNITHRSLSSLCASLKLACELYPSRHVALCLDPYCGLGFVMWTLIGVYSGHHSILIAPYEVEANPSLWLSTLSQHRVRDTFCSYGVIELCTKALSNSIPSLKQRNIDLRCVRTCVVVAEERPRVQLTQQFCKLFQALGLNTRCVSTSFGCRVNPAICVQGASSAESAQVYVDMRALRNNRVALVERGAPNSLCVIESGKLLPGVKVIIANPETKGHCGDSHLGEIWVQAPHNANGYFTIYGDETDYNDHFNAKLVTGATSELYARTGYLGFLRRTECSQSASLLDETTPSVASRDSDTESLNSISQLQLNFSNVSLGGNSEHSLVGGASNANDQELHDAVYVVGAVDEVISLRGMNYHPIDIENSVMRCHKKIAECAVFTWTNLLVVVVELDGNESEALDLVPLVTNTVLEDHQLIVGVVVVVDPGVVPINSRGEKQRMHLRDGFLADQLDPIYVAYNM", "length": 1773, "header": "sp|Q9W0S9-1|DIP2_DROME Isoform 1 of Disco-interacting protein 2 OS=Drosophila melanogaster OX=7227 GN=DIP2 PE=1 SV=2 CANONICAL=Q9W0S9-1" }, "isoforms": [ { "isoform_ac": "M9NDW1-1", "url": "", "sequence": { "sequence": "MEHTASLPGYVREKLAELDLELSEGDITQKGYEKKRAKLLQPFLKKPEGDKVKSTPPPPYYNVKNANNSTNHGNINNDGVIVSSEGYSYVTEVPSLSSSQQRHSKKIDFHQQAAMSLSSAPQSGNAGAPGYENMRPQGGAVGDPGYQNTREPSAFQNQQSTNNSQHRQRRTQRKVTHNEKRYHSVRQEAVQQALAALKGRPKPSLPMPSKRTSVLNRSPGCNDELDSSTDDESIPEETISPDKEYNYPRDHISNSILPPEPIIKPPIRESSMGSQQHARTDVKQNQITNQKYTAPNSAPERRPPQNLPPLPTSEPLSSDYPPIAYKRENDFSDKAFKQKQYNAPDITQFNNAHRAADRVTRYVNVSQNELNETDANGKWKVSAKIQQLLNTLKRPKRRPLPEFYEDNDIELEIAANTKDPNAPKPEGSTMTPVQGEQLSIPAGLPRTLECALQRYGTNSFKSPMATVLDPNGKVTTTLTYGKLLSRAQKIAHALSTKIFSKGPEQVTLKPGDRVALVYPNNDPLSFITAWYGCMFRGLVPLPIELPLSSSDTPPQQVGFLLSSCGITVALTSEACLKGLPKSTTTGEIAKLKGWPRLQWFVTEHLPKPPKEFNVGNLRADDSAAAYIEYTTDKEGSVMGVTVTRAAMINHCRALTMACHYTEGETIVCVLDFKREVGLWHSVLTSVLNGMHVIFIPYALMKLRPSSWMQLITKHRASCCLVKSRDLHWGLLATKDHKDISLSSLRMLLVADGANPWSLSSCDQFLSVFQAKGLRSDAICPCASSSEVFTVSLRRPGRGSCGFSPSATGRGVLSMAALSHGVVRVDSEDSLTSLTLQDCGQVMPAAQMVVVRSEGPPVLCKTDQVGEICVTSGSTSASYFGLDGMTNSTFKVQPLLEELEQPKDGNGTVNIISKPIGEDFYVRSGLLGFLGPGGLVFVCGSRDGLMTVTGRKHNADDIIATVLAVEPMRFIYRGRIAVFSIKVLRDERVCVIAEQRPDCSEEESFQWMSRVLQAVDSIHQVGIYCLALVPPNHLPKTPLGGIHLCEARRRFLEGSLHPANVLMCPHTCVTNLPKPRELHQDTGVGPASVMVGNLVQGNRLAEAHGRDVGLAEDCERKPQLITGVLRWRANTSPDHIIFTLLNSKGAIAKTLTCSELHKRAEKIAALLQERGRIEPGDHVALIFPPGLDLLCAFYGCLYLGAIPITIRPPHPQNLNTTLPTVRMIVDVSKSGIVLSIQPIIKLLKSREAATSIDPKTWPPILDIDDNPKRKYAGIATVSFDSSAYLDFSVSTCGRLSGVNITHRSLSSLCASLKLACELYPSRHVALCLDPYCGLGFVMWTLIGVYSGHHSILIAPYEVEANPSLWLSTLSQHRVRDTFCSYGVIELCTKALSNSIPSLKQRNIDLRCVRTCVVVAEERPRVQLTQQFCKLFQALGLNTRCVSTSFGCRVNPAICVQGASSAESAQVYVDMRALRNNRVALVERGAPNSLCVIESGKLLPGVKVIIANPETKGHCGDSHLGEIWVQAPHNANGYFTIYGDETDYNDHFNAKLVTGATSELYARTGYLGFLRRTECSQSASLLDETTPSVASRDSDTESLNSISQLQLNFSNVSLGGNSEHSLVGGASNANDQELHDAVYVVGAVDEVISLRGMNYHPIDIENSVMRCHKKIAECAVFTWTNLLVVVVELDGNESEALDLVPLVTNTVLEDHQLIVGVVVVVDPGVVPINSRGEKQRMHLRDGFLADQLDPIYVAYNM", "length": 1755, "header": "tr|M9NDW1-1|M9NDW1_DROME Computationally mapped isoform of DISCO interacting protein 2, isoform B OS=Drosophila melanogaster OX=7227 GN=DIP2 PE=3 SV=1 CANONICAL=Q9W0S9-1" }, "locus": { "chromosome": "3L", "start_pos": 257625, "end_pos": 250513, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0305325", "url": "https://www.ensembl.org/id/FBtr0305325" }, { "database": "Ensembl Peptide", "id": "FBpp0293868", "url": "https://www.ensembl.org/id/FBpp0293868" } ] } }, { "isoform_ac": "M9PBG6-1", "url": "", "sequence": { "sequence": "MEHTASLPGYVREKLAELDLELSEGDITQKGYEKKRAKLLQPFLKKPEGDKVKSTPPPPYYNVKNANNSTNHGNINNDGVIVSSEGYSYVTEVPSLSSSQQRHSKKIDFHQQAAMSLSSAPQSGNAGAPGYENMRPQGGAVGDPGYQNTREPSAFQNQQSTNNSQHRQRRTQRKVTHNEKRYHSVRQEAVQQALAALKGRPKPSLPMPSKRTSVLNRSPGCNDELDSSTDDESIPEETISPDKEYNYPRDHISNSILPPEPIIKPPIRESSMGSQQHARTDVKQNQITNQKYTAPNSAPERRPPQNLPPLPTSEPLSSDYPPIAYKRENDFSDKAFKQKQYNAPDITQFNNAHRAADRVTRYVNVSQNELNETDANGKWKVSAKIQQLLNTLKRPKRRPLPEFYEDNDIELEIAANTKDPNAPKPEGSTMTPVQGEQLSIPAGLPRTLECALQRYGTNSFKSPMATVLDPNGKVTTTLTYGKLLSRAQKIAHALSTKIFSKGPEQVTLKPGDRVALVYPNNDPLSFITAWYGCMFRGLVPLPIELPLSSSDTPPQQVGFLLSSCGITVALTSEACLKGLPKSTTTGEIAKLKGWPRLQWFVTEHLPKPPKEFNVGNLRADDSAAAYIEYTTDKEGSVMGVTVTRAAMINHCRALTMACHYTEGETIVCVLDFKREVGLWHSVLTSVLNGMHVIFIPYALMKLRPSSWMQLITKHRASCCLVKSRDLHWGLLATKDHKDISLSSLRMLLVADGANPWSLSSCDQFLSVFQAKGLRSDAICPCASSSEVFTVSLRRPGRGSCGFSPSATGRGVLSMAALSHGVVRVDSEDSLTSLTLQDCGQVMPAAQMVVVRSEGPPVLCKTDQVGEICVTSGSTSASYFGLDGMTNSTFKVQPLLEELEQPKDGNGTVNIISKPIGEDFYVRSGLLGFLGPGGLVFVCGSRDGLMTVTGRKHNADDIIATVLAVEPMRFIYRGRIAVFSIKVLRDERVCVIAEQRPDCSEEESFQWMSRVLQAVDSIHQVGIYCLALVPPNHLPKTPLGGIHLCEARRRFLEGSLHPANVLMCPHTCVTNLPKPRELHQGVQTAAKLSSSSGCGITDTGVGPASVMVGNLVQGNRLAEAHGRDVGLAEDCERKPQLITGVLRWRANTSPDHIIFTLLNSKGAIAKTLTCSELHKRAEKIAALLQERGRIEPGDHVALIFPPGLDLLCAFYGCLYLGAIPITIRPPHPQNLNTTLPTVRMIVDVSKSGIVLSIQPIIKLLKSREAATSIDPKTWPPILDIDDNPKRKYAGIATVSFDSSAYLDFSVSTCGRLSGVNITHRSLSSLCASLKLACELYPSRHVALCLDPYCGLGFVMWTLIGVYSGHHSILIAPYEVEANPSLWLSTLSQHRVRDTFCSYGVIELCTKALSNSIPSLKQRNIDLRCVRTCVVVAEERPRVQLTQQFCKLFQALGLNTRCVSTSFGCRVNPAICVQGASSAESAQVYVDMRALRNNRVALVERGAPNSLCVIESGKLLPGVKVIIANPETKGHCGDSHLGEIWVQAPHNANGYFTIYGDETDYNDHFNAKLVTGATSELYARTGYLGFLRRTECSQSASLLDETTPSVASRDSDTESLNSISQLQLNFSNVSLGGNSEHSLVGGASNANDQELHDAVYVVGAVDEVISLRGMNYHPIDIENSVMRCHKKIAECAVFTWTNLLVVVVELDGNESEALDLVPLVTNTVLEDHQLIVGVVVVVDPGVVPINSRGEKQRMHLRDGFLADQLDPIYVAYNM", "length": 1772, "header": "tr|M9PBG6-1|M9PBG6_DROME Computationally mapped isoform of DISCO interacting protein 2, isoform D OS=Drosophila melanogaster OX=7227 GN=DIP2 PE=3 SV=1 CANONICAL=Q9W0S9-1" }, "locus": { "chromosome": "3L", "start_pos": 257625, "end_pos": 250513, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0332109", "url": "https://www.ensembl.org/id/FBtr0332109" }, { "database": "Ensembl Peptide", "id": "FBpp0304419", "url": "https://www.ensembl.org/id/FBpp0304419" } ] } }, { "isoform_ac": "M9PDH5-1", "url": "", "sequence": { "sequence": "MEHTASLPGYVREKLAELDLELSEGDITQKGYEKKRAKLLQPFLKKPEGDKVKSTPPPPYYNVKNANNSTNHGNINNDGVIVSSEGYSYVTEVPSLSSSQQRHSKKIDFHQQAAMSLSSAPQSGNAGAPGYENMRPQGGAVGDPGYQNTREPSAFQNQQSTNNSQHRQRRTQRKVTHNEKRYHSEVRQEAVQQALAALKGRPKPSLPMPSKRTSVLNRSPGCNDELDSSTDDESIPEETISPDKEYNYPRDHISNSILPPEPIIKPPIRESSMGSQQHARTDVKQNQITNQKYTAPNSAPERRPPQNLPPLPTSEPLSSDYPPIAYKRENDFSDKAFKQKQYNAPDITQFNNAHRAADRVTRYVNVSQNELNETDANGKWKVSAKIQQLLNTLKRPKRRPLPEFYEDNDIELEIAANTKDPNAPKPEGSTMTPVQGEQLSIPAGLPRTLECALQRYGTNSFKSPMATVLDPNGKVTTTLTYGKLLSRAQKIAHALSTKIFSKGPEQVTLKPGDRVALVYPNNDPLSFITAWYGCMFRGLVPLPIELPLSSSDTPPQQVGFLLSSCGITVALTSEACLKGLPKSTTTGEIAKLKGWPRLQWFVTEHLPKPPKEFNVGNLRADDSAAAYIEYTTDKEGSVMGVTVTRAAMINHCRALTMACHYTEGETIVCVLDFKREVGLWHSVLTSVLNGMHVIFIPYALMKLRPSSWMQLITKHRASCCLVKSRDLHWGLLATKDHKDISLSSLRMLLVADGANPWSLSSCDQFLSVFQAKGLRSDAICPCASSSEVFTVSLRRPGRGSCGFSPSATGRGVLSMAALSHGVVRVDSEDSLTSLTLQDCGQVMPAAQMVVVRSEGPPVLCKTDQVGEICVTSGSTSASYFGLDGMTNSTFKVQPLLEELEQPKDGNGTVNIISKPIGEDFYVRSGLLGFLGPGGLVFVCGSRDGLMTVTGRKHNADDIIATVLAVEPMRFIYRGRIAVFSIKVLRDERVCVIAEQRPDCSEEESFQWMSRVLQAVDSIHQVGIYCLALVPPNHLPKTPLGGIHLCEARRRFLEGSLHPANVLMCPHTCVTNLPKPRELHQGVQTAAKLSSSSGCGITDTGVGPASVMVGNLVQGNRLAEAHGRDVGLAEDCERKPQLITGVLRWRANTSPDHIIFTLLNSKGAIAKTLTCSELHKRAEKIAALLQERGRIEPGDHVGLDLLCAFYGCLYLGAIPITIRPPHPQNLNTTLPTVRMIVDVSKSGIVLSIQPIIKLLKSREAATSIDPKTWPPILDIDDNPKRKYAGIATVSFDSSAYLDFSVSTCGRLSGVNITHRSLSSLCASLKLACELYPSRHVALCLDPYCGLGFVMWTLIGVYSGHHSILIAPYEVEANPSLWLSTLSQHRVRDTFCSYGVIELCTKALSNSIPSLKQRNIDLRCVRTCVVVAEERPRVQLTQQFCKLFQALGLNTRCVSTSFGCRVNPAICVQGASSAESAQVYVDMRALRNNRVALVERGAPNSLCVIESGKLLPGVKVIIANPETKGHCGDSHLGEIWVQAPHNANGYFTIYGDETDYNDHFNAKLVTGATSELYARTGYLGFLRRTECSQSASLLDETTPSVASRDSDTESLNSISQLQLNFSNVSLGGNSEHSLVGGASNANDQELHDAVYVVGAVDEVISLRGMNYHPIDIENSVMRCHKKIAECAVFTWTNLLVVVVELDGNESEALDLVPLVTNTVLEDHQLIVGVVVVVDPGVVPINSRGEKQRMHLRDGFLADQLDPIYVAYNM", "length": 1767, "header": "tr|M9PDH5-1|M9PDH5_DROME Computationally mapped isoform of DISCO interacting protein 2, isoform E OS=Drosophila melanogaster OX=7227 GN=DIP2 PE=3 SV=1 CANONICAL=Q9W0S9-1" }, "locus": { "chromosome": "3L", "start_pos": 257625, "end_pos": 250513, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0332110", "url": "https://www.ensembl.org/id/FBtr0332110" }, { "database": "Ensembl Peptide", "id": "FBpp0304420", "url": "https://www.ensembl.org/id/FBpp0304420" } ] } }, { "isoform_ac": "M9PGJ0-1", "url": "", "sequence": { "sequence": "MEHTASLPGYVREKLAELDLELSEGDITQKGYEKKRAKLLQPFLKKPEGDKVKSTPPPPYYNVKNANNSTNHGNINNDGVIVSSEGYSYVTEVPSLSSSQQRHSKKIDFHQQAAMSLSSAPQSGNAGAPGYENMRPQGGAVGDPGYQNTREPSAFQNQQSTNNSQHRQRRTQRKVTHNEKRYHSEVRQEAVQQALAALKGRPKPSLPMPSKRTSVLNRSPGCNDELDSSTDDESIPEETISPDKEYNYPRDHISNSILPPEPIIKPPIRESSMGSQQHARTDVKQNQITNQKYTAPNSAPERRPPQNLPPLPTSEPLSSDYPPIAYKRENDFSDKAFKQKQYNAPDITQFNNAHRAADRVTRYVNVSQNELNETDANGKWKVSAKIQQLLNTLKRPKRRPLPEFYEDNDIELEIAANTKDPNAPKPEGSTMTPVQGEQLSIPAGLPRTLECALQRYGTNSFKSPMATVLDPNGKVTTTLTYGKLLSRAQKIAHALSTKIFSKGPEQVTLKPGDRVALVYPNNDPLSFITAWYGCMFRGLVPLPIELPLSSSDTPPQQVGFLLSSCGITVALTSEACLKGLPKSTTTGEIAKLKGWPRLQWFVTEHLPKPPKEFNVGNLRADDSAAAYIEYTTDKEGSVMGVTVTRAAMINHCRALTMACHYTEGETIVCVLDFKREVGLWHSVLTSVLNGMHVIFIPYALMKLRPSSWMQLITKHRASCCLVKSRDLHWGLLATKDHKDISLSSLRMLLVADGANPWSLSSCDQFLSVFQAKGLRSDAICPCASSSEVFTVSLRRPGRGSCGFSPSATGRGVLSMAALSHGVVRVDSEDSLTSLTLQDCGQVMPAAQMVVVRSEGPPVLCKTDQVGEICVTSGSTSASYFGLDGMTNSTFKVQPLLEELEQPKDGNGTVNIISKPIGEDFYVRSGLLGFLGPGGLVFVCGSRDGLMTVTGRKHNADDIIATVLAVEPMRFIYRGRIAVFSIKVLRDERVCVIAEQRPDCSEEESFQWMSRVLQAVDSIHQVGIYCLALVPPNHLPKTPLGGIHLCEARRRFLEGSLHPANVLMCPHTCVTNLPKPRELHQDTGVGPASVMVGNLVQGNRLAEAHGRDVGLAEDCERKPQLITGVLRWRANTSPDHIIFTLLNSKGAIAKTLTCSELHKRAEKIAALLQERGRIEPGDHVALIFPPGLDLLCAFYGCLYLGAIPITIRPPHPQNLNTTLPTVRMIVDVSKSGIVLSIQPIIKLLKSREAATSIDPKTWPPILDIDDNPKRKYAGIATVSFDSSAYLDFSVSTCGRLSGVNITHRSLSSLCASLKLACELYPSRHVALCLDPYCGLGFVMWTLIGVYSGHHSILIAPYEVEANPSLWLSTLSQHRVRDTFCSYGVIELCTKALSNSIPSLKQRNIDLRCVRTCVVVAEERPRVQLTQQFCKLFQALGLNTRCVSTSFGCRVNPAICVQGASSAESAQVYVDMRALRNNRVALVERGAPNSLCVIESGKLLPGVKVIIANPETKGHCGDSHLGEIWVQAPHNANGYFTIYGDETDYNDHFNAKLVTGATSELYARTGYLGFLRRTECSQSASLLDETTPSVASRDSDTESLNSISQLQLNFSNVSLGGNSEHSLVGGASNANDQELHDAVYVVGAVDEVISLRGMNYHPIDIENSVMRCHKKIAECAVFTWTNLLVVVVELDGNESEALDLVPLVTNTVLEDHQLIVGVVVVVDPGVVPINSRGEKQRMHLRDGFLADQLDPIYVAYNM", "length": 1756, "header": "tr|M9PGJ0-1|M9PGJ0_DROME Computationally mapped isoform of DISCO interacting protein 2, isoform C OS=Drosophila melanogaster OX=7227 GN=DIP2 PE=3 SV=1 CANONICAL=Q9W0S9-1" }, "locus": { "chromosome": "3L", "start_pos": 257625, "end_pos": 250513, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0332108", "url": "https://www.ensembl.org/id/FBtr0332108" }, { "database": "Ensembl Peptide", "id": "FBpp0304418", "url": "https://www.ensembl.org/id/FBpp0304418" } ] } }, { "isoform_ac": "Q9W0S9-1", "url": "", "sequence": { "sequence": "MEHTASLPGYVREKLAELDLELSEGDITQKGYEKKRAKLLQPFLKKPEGDKVKSTPPPPYYNVKNANNSTNHGNINNDGVIVSSEGYSYVTEVPSLSSSQQRHSKKIDFHQQAAMSLSSAPQSGNAGAPGYENMRPQGGAVGDPGYQNTREPSAFQNQQSTNNSQHRQRRTQRKVTHNEKRYHSEVRQEAVQQALAALKGRPKPSLPMPSKRTSVLNRSPGCNDELDSSTDDESIPEETISPDKEYNYPRDHISNSILPPEPIIKPPIRESSMGSQQHARTDVKQNQITNQKYTAPNSAPERRPPQNLPPLPTSEPLSSDYPPIAYKRENDFSDKAFKQKQYNAPDITQFNNAHRAADRVTRYVNVSQNELNETDANGKWKVSAKIQQLLNTLKRPKRRPLPEFYEDNDIELEIAANTKDPNAPKPEGSTMTPVQGEQLSIPAGLPRTLECALQRYGTNSFKSPMATVLDPNGKVTTTLTYGKLLSRAQKIAHALSTKIFSKGPEQVTLKPGDRVALVYPNNDPLSFITAWYGCMFRGLVPLPIELPLSSSDTPPQQVGFLLSSCGITVALTSEACLKGLPKSTTTGEIAKLKGWPRLQWFVTEHLPKPPKEFNVGNLRADDSAAAYIEYTTDKEGSVMGVTVTRAAMINHCRALTMACHYTEGETIVCVLDFKREVGLWHSVLTSVLNGMHVIFIPYALMKLRPSSWMQLITKHRASCCLVKSRDLHWGLLATKDHKDISLSSLRMLLVADGANPWSLSSCDQFLSVFQAKGLRSDAICPCASSSEVFTVSLRRPGRGSCGFSPSATGRGVLSMAALSHGVVRVDSEDSLTSLTLQDCGQVMPAAQMVVVRSEGPPVLCKTDQVGEICVTSGSTSASYFGLDGMTNSTFKVQPLLEELEQPKDGNGTVNIISKPIGEDFYVRSGLLGFLGPGGLVFVCGSRDGLMTVTGRKHNADDIIATVLAVEPMRFIYRGRIAVFSIKVLRDERVCVIAEQRPDCSEEESFQWMSRVLQAVDSIHQVGIYCLALVPPNHLPKTPLGGIHLCEARRRFLEGSLHPANVLMCPHTCVTNLPKPRELHQGVQTAAKLSSSSGCGITDTGVGPASVMVGNLVQGNRLAEAHGRDVGLAEDCERKPQLITGVLRWRANTSPDHIIFTLLNSKGAIAKTLTCSELHKRAEKIAALLQERGRIEPGDHVALIFPPGLDLLCAFYGCLYLGAIPITIRPPHPQNLNTTLPTVRMIVDVSKSGIVLSIQPIIKLLKSREAATSIDPKTWPPILDIDDNPKRKYAGIATVSFDSSAYLDFSVSTCGRLSGVNITHRSLSSLCASLKLACELYPSRHVALCLDPYCGLGFVMWTLIGVYSGHHSILIAPYEVEANPSLWLSTLSQHRVRDTFCSYGVIELCTKALSNSIPSLKQRNIDLRCVRTCVVVAEERPRVQLTQQFCKLFQALGLNTRCVSTSFGCRVNPAICVQGASSAESAQVYVDMRALRNNRVALVERGAPNSLCVIESGKLLPGVKVIIANPETKGHCGDSHLGEIWVQAPHNANGYFTIYGDETDYNDHFNAKLVTGATSELYARTGYLGFLRRTECSQSASLLDETTPSVASRDSDTESLNSISQLQLNFSNVSLGGNSEHSLVGGASNANDQELHDAVYVVGAVDEVISLRGMNYHPIDIENSVMRCHKKIAECAVFTWTNLLVVVVELDGNESEALDLVPLVTNTVLEDHQLIVGVVVVVDPGVVPINSRGEKQRMHLRDGFLADQLDPIYVAYNM", "length": 1773, "header": "sp|Q9W0S9-1|DIP2_DROME Isoform 1 of Disco-interacting protein 2 OS=Drosophila melanogaster OX=7227 GN=DIP2 PE=1 SV=2 CANONICAL=Q9W0S9-1" }, "locus": { "chromosome": "3L", "start_pos": 257625, "end_pos": 250513, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0072520", "url": "https://www.ensembl.org/id/FBtr0072520" }, { "database": "Ensembl Peptide", "id": "FBpp0072420", "url": "https://www.ensembl.org/id/FBpp0072420" } ] } } ], "glycosylation": [], "phosphorylation": [ { "start_pos": 60, "end_pos": 60, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "Q9W0S9", "url": "https://www.uniprot.org/uniprot/Q9W0S9" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "phospho.ELM", "id": "Q9W0S9", "url": "http://phospho.elm.eu.org/byAccession/Q9W0S9.html" }, { "database": "iPTMnet", "id": "Q9W0S9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9W0S9" } ], "site_lbl": "Tyr60" }, { "start_pos": 61, "end_pos": 61, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "Q9W0S9", "url": "https://www.uniprot.org/uniprot/Q9W0S9" }, { "database": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" }, { "database": "phospho.ELM", "id": "Q9W0S9", "url": "http://phospho.elm.eu.org/byAccession/Q9W0S9.html" }, { "database": "iPTMnet", "id": "Q9W0S9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9W0S9" } ], "site_lbl": "Tyr61" } ], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9W0S9", "url": "https://www.uniprot.org/uniprot/Q9W0S9" }, { "database": "UniProtKB", "id": "M9NDW1", "url": "https://www.uniprot.org/uniprot/M9NDW1" }, { "database": "UniProtKB", "id": "M9PGJ0", "url": "https://www.uniprot.org/uniprot/M9PGJ0" }, { "database": "UniProtKB", "id": "M9PDH5", "url": "https://www.uniprot.org/uniprot/M9PDH5" }, { "database": "UniProtKB", "id": "M9PBG6", "url": "https://www.uniprot.org/uniprot/M9PBG6" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Cloning, genomic organization and expression pattern of a novel Drosophila gene, the disco-interacting protein 2 (dip2), and its murine homolog.", "journal": "Gene", "date": "2002", "authors": "Mukhopadhyay M, Pelka P, DeSousa D, Kablar B, Schindler A, Rudnicki MA, Campos AR", "evidence": [ { "database": "UniProtKB", "id": "Q9W0S9", "url": "https://www.uniprot.org/uniprot/Q9W0S9" } ], "reference": [ { "type": "PubMed", "id": "12137943", "url": "https://glygen.org/publication/PubMed/12137943" } ] }, { "title": "Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence.", "journal": "Genome Biol.", "date": "2002", "authors": "Celniker SE, Wheeler DA, Kronmiller B, Carlson JW, Halpern A, Patel S, Adams M, Champe M, Dugan SP, Frise E, Hodgson A, George RA, Hoskins RA, Laverty T, Muzny DM, Nelson CR, Pacleb JM, Park S, Pfeiffer BD, Richards S, Sodergren EJ, Svirskas R, Tabor PE, Wan K, Stapleton M, Sutton GG, Venter C, Weinstock G, Scherer SE, Myers EW, Gibbs RA, Rubin GM", "evidence": [ { "database": "UniProtKB", "id": "M9NDW1", "url": "https://www.uniprot.org/uniprot/M9NDW1" }, { "database": "UniProtKB", "id": "M9PGJ0", "url": "https://www.uniprot.org/uniprot/M9PGJ0" }, { "database": "UniProtKB", "id": "M9PDH5", "url": "https://www.uniprot.org/uniprot/M9PDH5" }, { "database": "UniProtKB", "id": "M9PBG6", "url": "https://www.uniprot.org/uniprot/M9PBG6" } ], "reference": [ { "type": "PubMed", "id": "12537568", "url": "https://glygen.org/publication/PubMed/12537568" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9W0S9", "url": "https://www.uniprot.org/uniprot/Q9W0S9" }, { "database": "UniProtKB", "id": "M9NDW1", "url": "https://www.uniprot.org/uniprot/M9NDW1" }, { "database": "UniProtKB", "id": "M9PGJ0", "url": "https://www.uniprot.org/uniprot/M9PGJ0" }, { "database": "UniProtKB", "id": "M9PDH5", "url": "https://www.uniprot.org/uniprot/M9PDH5" }, { "database": "UniProtKB", "id": "M9PBG6", "url": "https://www.uniprot.org/uniprot/M9PBG6" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective.", "journal": "Genome Biol.", "date": "2002", "authors": "Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "M9NDW1", "url": "https://www.uniprot.org/uniprot/M9NDW1" }, { "database": "UniProtKB", "id": "M9PGJ0", "url": "https://www.uniprot.org/uniprot/M9PGJ0" }, { "database": "UniProtKB", "id": "M9PDH5", "url": "https://www.uniprot.org/uniprot/M9PDH5" }, { "database": "UniProtKB", "id": "M9PBG6", "url": "https://www.uniprot.org/uniprot/M9PBG6" } ], "reference": [ { "type": "PubMed", "id": "12537573", "url": "https://glygen.org/publication/PubMed/12537573" } ] }, { "title": "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly.", "journal": "Genome Biol.", "date": "2002", "authors": "Hoskins RA, Smith CD, Carlson JW, Carvalho AB, Halpern A, Kaminker JS, Kennedy C, Mungall CJ, Sullivan BA, Sutton GG, Yasuhara JC, Wakimoto BT, Myers EW, Celniker SE, Rubin GM, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "M9NDW1", "url": "https://www.uniprot.org/uniprot/M9NDW1" }, { "database": "UniProtKB", "id": "M9PGJ0", "url": "https://www.uniprot.org/uniprot/M9PGJ0" }, { "database": "UniProtKB", "id": "M9PDH5", "url": "https://www.uniprot.org/uniprot/M9PDH5" }, { "database": "UniProtKB", "id": "M9PBG6", "url": "https://www.uniprot.org/uniprot/M9PBG6" } ], "reference": [ { "type": "PubMed", "id": "12537574", "url": "https://glygen.org/publication/PubMed/12537574" } ] }, { "title": "Combined evidence annotation of transposable elements in genome sequences.", "journal": "PLoS Comput. Biol.", "date": "2005", "authors": "Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D", "evidence": [ { "database": "UniProtKB", "id": "M9NDW1", "url": "https://www.uniprot.org/uniprot/M9NDW1" }, { "database": "UniProtKB", "id": "M9PGJ0", "url": "https://www.uniprot.org/uniprot/M9PGJ0" }, { "database": "UniProtKB", "id": "M9PDH5", "url": "https://www.uniprot.org/uniprot/M9PDH5" }, { "database": "UniProtKB", "id": "M9PBG6", "url": "https://www.uniprot.org/uniprot/M9PBG6" } ], "reference": [ { "type": "PubMed", "id": "16110336", "url": "https://glygen.org/publication/PubMed/16110336" } ] }, { "title": "The Release 5.1 annotation of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Smith CD, Shu S, Mungall CJ, Karpen GH", "evidence": [ { "database": "UniProtKB", "id": "M9NDW1", "url": "https://www.uniprot.org/uniprot/M9NDW1" }, { "database": "UniProtKB", "id": "M9PGJ0", "url": "https://www.uniprot.org/uniprot/M9PGJ0" }, { "database": "UniProtKB", "id": "M9PDH5", "url": "https://www.uniprot.org/uniprot/M9PDH5" }, { "database": "UniProtKB", "id": "M9PBG6", "url": "https://www.uniprot.org/uniprot/M9PBG6" } ], "reference": [ { "type": "PubMed", "id": "17569856", "url": "https://glygen.org/publication/PubMed/17569856" } ] }, { "title": "Sequence finishing and mapping of Drosophila melanogaster heterochromatin.", "journal": "Science", "date": "2007", "authors": "Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE", "evidence": [ { "database": "UniProtKB", "id": "M9NDW1", "url": "https://www.uniprot.org/uniprot/M9NDW1" }, { "database": "UniProtKB", "id": "M9PGJ0", "url": "https://www.uniprot.org/uniprot/M9PGJ0" }, { "database": "UniProtKB", "id": "M9PDH5", "url": "https://www.uniprot.org/uniprot/M9PDH5" }, { "database": "UniProtKB", "id": "M9PBG6", "url": "https://www.uniprot.org/uniprot/M9PBG6" } ], "reference": [ { "type": "PubMed", "id": "17569867", "url": "https://glygen.org/publication/PubMed/17569867" } ] }, { "title": "Phosphoproteome analysis of Drosophila melanogaster embryos.", "journal": "Journal of proteome research", "date": "2008", "authors": "Zhai B, Villen J, Beausoleil SA, Mintseris J, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q9W0S9", "url": "https://www.uniprot.org/uniprot/Q9W0S9" }, { "database": "iPTMnet", "id": "Q9W0S9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9W0S9" } ], "reference": [ { "type": "PubMed", "id": "18327897", "url": "https://glygen.org/publication/PubMed/18327897" } ] }, { "title": "DISCO Interacting Protein 2 regulates axonal bifurcation and guidance of Drosophila mushroom body neurons.", "journal": "Dev. Biol.", "date": "2017", "authors": "Nitta Y., Tabata T., Yamazaki D., Hiroi M., Sugie A.", "evidence": [ { "database": "UniProtKB", "id": "Q9W0S9", "url": "https://www.uniprot.org/uniprot/Q9W0S9" } ], "reference": [ { "type": "PubMed", "id": "27908785", "url": "https://glygen.org/publication/PubMed/27908785" } ] }, { "title": "DISCO interacting protein 2 determines direction of axon projection under the regulation of c-Jun N-terminal kinase in the Drosophila mushroom body.", "journal": "Biochem. Biophys. Res. Commun.", "date": "2017", "authors": "Nitta Y., Sugie A.", "evidence": [ { "database": "UniProtKB", "id": "Q9W0S9", "url": "https://www.uniprot.org/uniprot/Q9W0S9" } ], "reference": [ { "type": "PubMed", "id": "28396149", "url": "https://glygen.org/publication/PubMed/28396149" } ] } ], "pathway": [ { "id": "dme:Dmel_CG7020", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+dme:Dmel_CG7020", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q12275-1", "protein_name": "Uncharacterized protein YOR093C", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": 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