{ "uniprot_canonical_ac": "Q9VTP4-1", "uniprot_ac": "Q9VTP4", "uniprot_id": "R10AB_DROME", "mass": { "chemical_mass": 24274.0, "monoisotopic_mass": 24274.0 }, "refseq": { "ac": "NP_648514", "name": "ribosomal protein L10Ab, isoform A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648514" }, "gene_names": [ { "name": "RpL10Ab", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/Q9VTP4", "id": "Q9VTP4" }, { "name": "CG7283", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q9VTP4", "id": "Q9VTP4" }, { "name": "RpL10Ab", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648514", "id": "NP_648514" }, { "name": "anon-EST:Posey188; BcDNA:RH06366; CG7283; Dmel\\CG7283; L1; L10Ab; RpL10; RpL10a; RpL10A; Rpl10ab; RpL10Ae", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648514", "id": "NP_648514" } ], "protein_names": [ { "name": "Large ribosomal subunit protein uL1", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "Q9VTP4" }, { "name": "60S ribosomal protein L10a-2", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q9VTP4" }, { "name": "CG7283-PA; RpL10Ab-PA; ribosomal protein L10Ab", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648514", "id": "NP_648514" }, { "name": "ribosomal protein L10Ab, isoform A", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648514", "id": "NP_648514" } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Drosophila melanogaster", "taxid": 7227, "evidence": [ { "database": "UniProtKB", "id": "Q9VTP4", "url": "https://www.uniprot.org/uniprot/Q9VTP4" } ], "common_name": "Fruit fly" } ], "gene": [ { "name": "RpL10Ab", "url": "https://www.uniprot.org/uniprot/Q9VTP4", "locus": { 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"database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016095", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016095", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023674", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023674", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028364", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028364", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dme:Dmel_CG7283", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+dme:Dmel_CG7283", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GPRNKMP", "url": "https://omabrowser.org/oma/group/GPRNKMP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "5095880at2759", "url": "http://www.orthodb.org/?query=5095880at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23105", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23105", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23105:SF101", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23105:SF101", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "4V6W", "url": "https://www.rcsb.org/structure/4V6W", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "6XU6", "url": "https://www.rcsb.org/structure/6XU6", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "6XU7", "url": "https://www.rcsb.org/structure/6XU7", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "6XU8", "url": "https://www.rcsb.org/structure/6XU8", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF00687", "url": "http://pfam.xfam.org/family/PF00687", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PR_Q9VTP4", "url": "http://purl.obolibrary.org/obo/PR_Q9VTP4", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-DME-156827", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-156827", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "R-DME-1799339", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1799339", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "R-DME-72689", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-72689", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "R-DME-72706", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-72706", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "R-DME-975956", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-975956", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "R-DME-975957", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-975957", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "NP_648514", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_648514", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9VTP4", "url": "https://www.uniprot.org/uniprot/Q9VTP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9VTP4-1", "url": "https://www.uniprot.org/uniprot/Q9VTP4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASKVSRDTLYEGVNGLLEASAKKKRGFLETVELQIGLKNYDPQKDKRFSGTVKLKHIPRPKMKVCILGDQQHCDEAKANNVDFMDAEALKKLNKNKKLVKKLAKSYDAFLASESLIKQIPRLLGPGLNKAGKFPALLSHQESMIGKIEEVKSTIKFQMKKVLCLSVAVGHVGMKSDELAQNVNLSINFLVSLLKKNWQNVRSLHVKSSMGPPQRLY", "length": 217, "header": "sp|Q9VTP4-1|R10AB_DROME Isoform 1 of Large ribosomal subunit protein uL1 OS=Drosophila melanogaster OX=7227 GN=RpL10Ab PE=1 SV=2 CANONICAL=Q9VTP4-1" }, "isoforms": [ { "isoform_ac": "Q9VTP4-1", "url": "", "sequence": { "sequence": "MASKVSRDTLYEGVNGLLEASAKKKRGFLETVELQIGLKNYDPQKDKRFSGTVKLKHIPRPKMKVCILGDQQHCDEAKANNVDFMDAEALKKLNKNKKLVKKLAKSYDAFLASESLIKQIPRLLGPGLNKAGKFPALLSHQESMIGKIEEVKSTIKFQMKKVLCLSVAVGHVGMKSDELAQNVNLSINFLVSLLKKNWQNVRSLHVKSSMGPPQRLY", "length": 217, "header": "sp|Q9VTP4-1|R10AB_DROME Isoform 1 of Large ribosomal subunit protein uL1 OS=Drosophila melanogaster OX=7227 GN=RpL10Ab PE=1 SV=2 CANONICAL=Q9VTP4-1" }, "locus": { "chromosome": "3L", "start_pos": 11824147, "end_pos": 11822886, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "FBtr0076032", "url": "https://www.ensembl.org/id/FBtr0076032" }, { "database": "Ensembl Peptide", "id": "FBpp0075764", "url": "https://www.ensembl.org/id/FBpp0075764" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The genome sequence of Drosophila melanogaster.", "journal": "Science", "date": "2000", "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC", "evidence": [ { "database": "UniProtKB", "id": "Q9VTP4", "url": "https://www.uniprot.org/uniprot/Q9VTP4" } ], "reference": [ { "type": "PubMed", "id": "10731132", "url": "https://glygen.org/publication/PubMed/10731132" } ] }, { "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.", "journal": "Genome Biol.", "date": "2002", "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE", "evidence": [ { "database": "UniProtKB", "id": "Q9VTP4", "url": "https://www.uniprot.org/uniprot/Q9VTP4" } ], "reference": [ { "type": "PubMed", "id": "12537572", "url": "https://glygen.org/publication/PubMed/12537572" } ] }, { "title": "Structures of the human and Drosophila 80S ribosome.", "journal": "Nature", "date": "2013", "authors": "Anger AM, Armache JP, Berninghausen O, Habeck M, Subklewe M, Wilson DN, Beckmann R", "evidence": [ { "database": "UniProtKB", "id": "Q9VTP4", "url": "https://www.uniprot.org/uniprot/Q9VTP4" } ], "reference": [ { "type": "PubMed", "id": "23636399", "url": "https://glygen.org/publication/PubMed/23636399" } ] } ], "pathway": [ { "id": "dme:Dmel_CG7283", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+dme:Dmel_CG7283", "resource": "KEGG Pathway" }, { "id": "R-DME-156827", "name": "L13a-mediated translational silencing of Ceruloplasmin expression", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-156827", "resource": "Reactome", "description": "L13a-mediated translational silencing of Ceruloplasmin expression" }, { "id": "R-DME-1799339", "name": "SRP-dependent cotranslational protein targeting to membrane", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-1799339", "resource": "Reactome", "description": "SRP-dependent cotranslational protein targeting to membrane" }, { "id": "R-DME-72689", "name": "Formation of a pool of free 40S subunits", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-72689", "resource": "Reactome", "description": "Formation of a pool of free 40S subunits" }, { "id": "R-DME-72706", "name": "GTP hydrolysis and joining of the 60S ribosomal subunit", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-72706", "resource": "Reactome", "description": "GTP hydrolysis and joining of the 60S ribosomal subunit" }, { "id": "R-DME-975956", "name": "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-975956", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" }, { "id": "R-DME-975957", "name": "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)", "url": "https://www.reactome.org/PathwayBrowser/#R-DME-975957", "resource": "Reactome", "description": "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" } ], "orthologs": [ { "uniprot_canonical_ac": "P0CX43-1", "protein_name": "Large ribosomal subunit protein uL1A", "gene_name": "RPL1A", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSKITSSQVREHVKELLKYSNETKKRNFLETVELQVGLKNYDPQRDKRFSGSLKLPNCPRPNMSICIFGDAFDVDRAKSCGVDAMSVDDLKKLNKNKKLIKKLSKKYNAFIASEVLIKQVPRLLGPQLSKAGKFPTPVSHNDDLYGKVTDVRSTIKFQLKKVLCLAVAVGNVEMEEDVLVNQILMSVNFFVSLLKKNWQNVGSLVVKSSMGPAFRLY", "length": 217 }, "evidence": [ { "id": "Q9VTP4", "url": "https://omabrowser.org/oma/group/Q9VTP4/", "database": "OMA" } ], "common_name": "Yeast" }, { "uniprot_canonical_ac": "P62906-1", "protein_name": "Large ribosomal subunit protein uL1", "gene_name": "RPL10A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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