{ "uniprot_canonical_ac": "Q9QYE7-1", "uniprot_ac": "Q9QYE7", "uniprot_id": "ITAD_RAT", "mass": { "chemical_mass": 126600.0, "monoisotopic_mass": 126600.0 }, "refseq": { "ac": "NP_113879", "name": "integrin alpha-D precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_113879" }, "gene_names": [ { "name": "Itgad", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/Q9QYE7", "id": "Q9QYE7" }, { "name": "Itgam", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/Q9QYE7", "id": "Q9QYE7" }, { "name": "Itgad", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_113879", "id": "NP_113879" }, { "name": "Itgad", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q9QYE7", "id": "Q9QYE7" }, { "name": "Itgax", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_113879", "id": "NP_113879" }, { "name": "Itgax", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q9QYE7", "id": "Q9QYE7" } ], "protein_names": [ { "name": "Integrin alpha-D", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "Q9QYE7" }, { "name": "integrin alpha-D precursor", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_113879", "id": "NP_113879" }, { "name": "integrin alpha-D; integrin alpha X (Cd11c)", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_113879", "id": "NP_113879" } ], "function": [ { "annotation": "An anti-CD11d monoclonal antibody improves motor performance, reduces pain and histopathological damage in animals following clip-compression injury.", "evidence": [ { "database": "RefSeq", "id": "NP_113879", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_113879" }, { "database": "PubMed", "id": "21145887", "url": "https://glygen.org/publication/PubMed/21145887" } ] }, { "annotation": "CD11d expression increased in retroperitoneal white adipose tissue of Zucker obese rats.", "evidence": [ { "database": "RefSeq", "id": "NP_113879", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_113879" }, { "database": "PubMed", "id": "21508205", "url": "https://glygen.org/publication/PubMed/21508205" } ] }, { "annotation": "Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. May play a role in the atherosclerotic process such as clearing lipoproteins from plaques and in phagocytosis of blood-borne pathogens, particulate matter, and senescent erythrocytes from the blood (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q9QYE7", "url": "https://www.uniprot.org/uniprot/Q9QYE7#function" } ] }, { "annotation": "Recovery from Antiglomerular Basement Membrane Glomerulonephritis Is Associated with Glomeruli-Infiltrating CD8alpha+CD11c+MHC Class II+ Cells", "evidence": [ { "database": "RefSeq", "id": "NP_113879", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_113879" }, { "database": "PubMed", "id": "22068125", "url": "https://glygen.org/publication/PubMed/22068125" } ] } ], "disease": [ { "disease_id": "DOID:0050852", "recommended_name": { "id": "DOID:0050852", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0050852", "name": "limb ischemia", "description": "An ischemia that is characterized by low blood supply to 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"preeclampsia/eclampsia 4", "description": "" }, { "id": "MONDO:0012266", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012266", "name": "PEE4", "description": "" }, { "id": "MONDO:0012266", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012266", "name": "PREECLAMPSIA/eclampsia 4", "description": "" }, { "id": "MONDO:0012265", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012265", "name": "preeclampsia/eclampsia 3", "description": "" }, { "id": "MONDO:0012265", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012265", "name": "PEE3", "description": "" }, { "id": "MONDO:0012265", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012265", "name": "PREECLAMPSIA/eclampsia 3", "description": "" }, { "id": "MONDO:0012264", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012264", "name": "preeclampsia/eclampsia 2", "description": "" }, { 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"noninsulin-dependent diabetes mellitus 1", "description": "" }, { "id": "MONDO:0011072", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011072", "name": "diabetes mellitus, noninsulin-dependent, 2", "description": "" }, { "id": "MONDO:0011072", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011072", "name": "NIDDM2", "description": "" }, { "id": "MONDO:0011072", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011072", "name": "diabetes mellitus, noninsulin-dependent, 2", "description": "" }, { "id": "MONDO:0011072", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011072", "name": "noninsulin-dependent diabetes mellitus 2", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "diabetes mellitus, noninsulin-dependent, 3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "diabetes mellitus, noninsulin-dependent, 3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "diabetes mellitus, noninsulin-dependent, type 3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "type 2 diabetes mellitus 3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "NIDDM3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "noninsulin-dependent diabetes mellitus 3", "description": "" }, { "id": "MIM:125853", "resource": "MIM", "url": "https://www.omim.org/entry/125853", "name": "Type 2 diabetes mellitus", "description": "Type 2 diabetes mellitus" }, { "id": "MIM:601283", "resource": "MIM", "url": "https://www.omim.org/entry/601283", "name": "Type 2 diabetes mellitus 1", "description": "Type 2 diabetes mellitus 1" } ], "evidence": [ { "id": "9352", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ] }, { "disease_id": "DOID:9408", "recommended_name": { "id": "DOID:9408", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:9408", "name": "acute myocardial infarction", "description": "" }, "synonyms": [], "evidence": [ { "id": "9408", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:9408" } ] }, { "disease_id": "DOID:9970", "recommended_name": { "id": "DOID:9970", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness." }, "synonyms": [ { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "inherited obesity", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "genetic obesity", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "genetic obesity (disease)", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "leanness, inherited, autosomal recessive", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "monogenic obesity", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "obesity, association with, Autosomal recessive", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "obesity, early-onset, susceptibility to, Autosomal recessive", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "obesity, late-onset, Autosomal recessive", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "obesity, mild, early-onset, Autosomal recessive", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "obesity, severe, Autosomal recessive", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "obesity, severe, and type II diabetes, Autosomal recessive", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "obesity, susceptibility to, Autosomal recessive", "description": "" }, { "id": "MIM:601665", "resource": "MIM", "url": "https://www.omim.org/entry/601665", "name": "Obesity", "description": "Obesity" } ], "evidence": [ { "id": "9970", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "Q9QYE7", "url": "https://www.uniprot.org/uniprot/Q9QYE7" } ], "common_name": "Rat" } ], "gene": [ { "name": "Itgad", "url": "https://www.uniprot.org/uniprot/Q9QYE7", "locus": { "chromosome": "1", "start_pos": 182788161, "end_pos": 182759740, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSRNOG00000068399", "url": "https://www.ensembl.org/id/ENSRNOG00000068399" } ] } } ], "crossref": [ { "id": "ENSRNOG00000019728", "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000019728", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01469", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01469", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "64350", "url": "https://www.ncbi.nlm.nih.gov/gene/64350", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000413", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000413", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013517", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013517", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013519", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013519", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013649", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013649", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018184", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018184", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028994", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028994", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032695", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032695", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "rno:64350", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:64350", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CQRIKCD", "url": "https://omabrowser.org/oma/group/CQRIKCD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "EHRYHVN", "url": "https://omabrowser.org/oma/group/EHRYHVN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "3816176at2759", "url": "http://www.orthodb.org/?query=3816176at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23220", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23220", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23220:SF130", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23220:SF130", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23220:SF132", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23220:SF132", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00092", "url": "http://pfam.xfam.org/family/PF00092", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF00357", "url": "http://pfam.xfam.org/family/PF00357", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF01839", "url": "http://pfam.xfam.org/family/PF01839", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF08441", "url": "http://pfam.xfam.org/family/PF08441", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PR_Q9QYE7", "url": "http://purl.obolibrary.org/obo/PR_Q9QYE7", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-RNO-216083", "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-216083", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "NP_113879", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_113879", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "2926", "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=2926", "database": "RGD", "categories": [ "Organism-specific" ] }, { "id": "71075", "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=71075", "database": "RGD", "categories": [ "Organism-specific" ] }, { "id": "A0A0G2K4L8", "url": "https://www.uniprot.org/uniprot/A0A0G2K4L8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0G2K4L8-1", "url": "https://www.uniprot.org/uniprot/A0A0G2K4L8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I5Y8A4", "url": "https://www.uniprot.org/uniprot/A0A8I5Y8A4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I5Y8A4-1", "url": "https://www.uniprot.org/uniprot/A0A8I5Y8A4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I5ZSN9", "url": "https://www.uniprot.org/uniprot/A0A8I5ZSN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I5ZSN9-1", "url": "https://www.uniprot.org/uniprot/A0A8I5ZSN9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I5ZVY4", "url": "https://www.uniprot.org/uniprot/A0A8I5ZVY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I5ZVY4-1", "url": "https://www.uniprot.org/uniprot/A0A8I5ZVY4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I6A686", "url": "https://www.uniprot.org/uniprot/A0A8I6A686", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I6A686-1", "url": "https://www.uniprot.org/uniprot/A0A8I6A686-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1M8G4", "url": "https://www.uniprot.org/uniprot/F1M8G4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1M8G4-1", "url": "https://www.uniprot.org/uniprot/F1M8G4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3V8L7", "url": "https://www.uniprot.org/uniprot/G3V8L7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3V8L7-1", "url": "https://www.uniprot.org/uniprot/G3V8L7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9QYE7", "url": "https://www.uniprot.org/uniprot/Q9QYE7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9QYE7-1", "url": "https://www.uniprot.org/uniprot/Q9QYE7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGGVVILLCGWVLASCHGSNLDVEEPIVFREDAASFGQTVVQFGGSRLVVGAPLEAVAVNQTGRLYDCAPATGMCQPIVLRSPLEAVNMSLGLSLVTATNNAQLLACGPTAQRACVKNMYAKGSCLLLGSSLQFIQAVPASMPECPRQEMDIAFLIDGSGSINQRDFAQMKDFVKALMGEFASTSTLFSLMQYSNILKTHFTFTEFKNILDPQSLVDPIVQLQGLTYTATGIRTVMEELFHSKNGSRKSAKKILLVITDGQKYRDPLEYSDVIPAADKAGIIRYAIGVGDAFQEPTALKELNTIGSAPPQDHVFKVGNFAALRSIQRQLQEKIFAIEGTQSRSSSSFQHEMSQEGFSSALTSDGPVLGAVGSFSWSGGAFLYPPNTRPTFINMSQENVDMRDSYLGYSTAVAFWKGVHSLILGAPRHQHTGKVVIFTQEARHWRPKSEVRGTQIGSYFGASLCSVDVDRDGSTDLVLIGAPHYYEQTRGGQVSVFPVPGVRGRWQCEATLHGEQGHPWGRFGVALTVLGDVNGDNLADVAIGAPGEEESRGAVYIFHGASRLEIMPSPSQRVTGSQLSLRLQYFGQSLSGGQDLTQDGLVDLAVGAQGHVLLLRSLPLLKVELSIRFAPMEVAKAVYQCWERTPTVLEAGEATVCLTVHKGSPDLLGNVQGSVRYDLALDPGRLISRAIFDETKNCTLTGRKTLGLGDHCETVKLLLPDCVEDAVSPIILRLNFSLVRDSASPRNLHPVLAVGSQDHITASLPFEKNCKQELLCEGDLGISFNFSGLQVLVVGGSPELTVTVTVWNEGEDSYGTLVKFYYPAGLSYRRVTGTQQPHQYPLRLACEAEPAAQEDLRSSSCSINHPIFREGAKTTFMITFDVSYKAFLGDRLLLRAKASSENNKPDTNKTAFQLELPVKYTVYTLISRQEDSTNHVNFSSSHGGRRQEAAHRYRVNNLSPLKLAVRVNFWVPVLLNGVAVWDVTLSSPAQGVSCVSQMKPPQNPDFLTQIQRRSVLDCSIADCLHFRCDIPSLDIQDELDFILRGNLSFGWVSQTLQEKVLLVSEAEITFDTSVYSQLPGQEAFLRAQVETTLEEYVVYEPIFLVAGSSVGGLLLLALITVVLYKLGFFKRQYKEMLDGKAADPVTAGQADFGCETPPYLVS", "length": 1161, "header": "sp|Q9QYE7-1|ITAD_RAT Isoform 1 of Integrin alpha-D OS=Rattus norvegicus OX=10116 GN=Itgad PE=2 SV=1 CANONICAL=Q9QYE7-1" }, "isoforms": [ { "isoform_ac": "A0A0G2K4L8-1", "url": "", "sequence": { "sequence": "MTLKFLLVTVLTLCHGFNLDTENPMTFQENARGFGQSVIQLGETRVVVAAPQEVKAVNQTGALYQCDYSTNRCDPIPLQVPPEAVNMSLGLSLAATTVPPQLLACGPTVHQNCKENTYVNGLCYLFGSNLLRKPQQFPEALRGCPQQESDIAFLIDGSGSINSIDFQKMKEFVSTVMDQFQKSKTLFSLMQYSDEFRTHFTFNDFKRNPDPKSHVRPIRQLNGRTKTASGIRKVVRELFQKINGARDNAAKILVVITDGEKFGDPLNYEDVIPEAEEAGIIRYVIGVGNAFHKPQSRRELDTIASKPAGDHVFQVDNFEALNTIRNQLQEKIFAIEGTQTGSTSSFEHEMSQEGFSAAITSNGPLLGSVGSFDWAGGAFLYPSKDKATFINTTRIDSDMNDAYLGYASAVISRNRVQSLVLGAPRYQHIGLVVMFKQNFGAWEPHTDIKGSQIGSYFGASLCSVDMDADGNTNLILIGAPHHYEKTRGGQVSVCPLPRGRARWQCEAILHGDQGHPWGRFGAALTVLGDVNGDKLTDVAIGAPGEQENQGAVYIFHGASVASISTPHSQRIAGARFSPGLQYFGQSLSGGKDLTMDGLMDLAVGAQGRLLLIRAQPVLRLEATMEFSPKNLARSVFACQEEVVKNKDAGEVRVCLHVRKNTKDRLREGDIQSTVTYDLALDPGRSVVRAFFDETKNGILRRIRVFGLTQKCETLKLILPDCVDNSVSPIILRLNYTLVGEPLRSSRDLRPVLAMEAQRIFTAMFPFEKNCGNDTICQDDLSITVSSIRVNTLVVGDSRDFDVSVTLRNDGEDSYGTKVTCYYPSGLSYRKVSASQNQFSKKPWRVIAEPSSSEGQGVLKSTIWDINHPIFPANSEVTFNVTFDVDSDASLGNKLLLKVVVTSENNVSRTDKTESQLELPVKYAIYMVVTSGESSIKYLNFTASEMTSKVIQHQYQFNNLGQRSFPVSVVFWIPVQINKVTIWDPPQVTFSQNLSSVCRTEQKSPSHSKFQDELERTPVLNCSVAVCKRIQCDIPSFNSKEIFNVTLQGNLLFDWYIETSHDHLLLVSTAEILFNDSAFALLPGQETFVKAQTETKVEPYKVHNPVPLIVGSSVGGLVLLALITAGLYKLGFFKRQYKDMMNEAAPQDGPPQ", "length": 1151, "header": "tr|A0A0G2K4L8-1|A0A0G2K4L8_RAT Computationally mapped isoform of Integrin subunit alpha M OS=Rattus norvegicus OX=10116 GN=Itgam PE=3 SV=2 CANONICAL=Q9QYE7-1" }, "locus": { "chromosome": "1", "start_pos": 182709048, "end_pos": 182659176, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000086003.2", "url": "https://www.ensembl.org/id/ENSRNOT00000086003.2" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000073093.2", "url": "https://www.ensembl.org/id/ENSRNOP00000073093.2" } ] } }, { "isoform_ac": "A0A8I5Y8A4-1", "url": "", "sequence": { "sequence": "MTGNVCCFLNCIGSFALTLNSLGFGQSVIQLGETRVVVAAPQEVKAVNQTGALYQCDYSTNRCDPIPLQVPPEAVNMSLGLSLAATTVPPQLLACGPTVHQNCKENTYVNGLCYLFGSNLLRKPQQFPEALRGCPQQESDIAFLIDGSGSINSIDFQKMKEFVSTVMDQFQKSKTLFSLMQYSDEFRTHFTFNDFKRNPDPKSHVRPIRQLNGRTKTASGIRKVVRELFQKINGARDNAAKILVVITDGEKFGDPLNYEDVIPEAEEAGIIRYVIGVGNAFHKPQSRRELDTIASKPAGDHVFQVDNFEALNTIRNQLQEKIFAIEGTQTGSTSSFEHEMSQEGFSAAITSNGPLLGSVGSFDWAGGAFLYPSKDKATFINTTRIDSDMNDAYLGYASAVISRNRVQSLVLGAPRYQHIGLVVMFKQNFGAWEPHTDIKGSQIGSYFGASLCSVDMDADGNTNLILIGAPHHYEKTRGGQVSVCPLPRGRARWQCEAILHGDQGHPWGRFGAALTVLGDVNGDKLTDVAIGAPGEQENQGAVYIFHGASVASISTPHSQRIAGARFSPGLQYFGQSLSGGKDLTMDGLMDLAVGAQGRLLLIRAQPVLRLEATMEFSPKNLARSVFACQEEVVKNKDAGEVRVCLHVRKNTKDRLREGDIQSTVTYDLALDPGRSVVRAFFDETKNGILRRIRVFGLTQKCETLKLILPDCVDNSVSPIILRLNYTLVGEPLRSSRDLRPVLAMEAQRIFTAMFPFEKNCGNDTICQDDLSITVSSIRVNTLVVGDSRDFDVSVTLRNDGEDSYGTKVTCYYPSGLSYRKVSASQNQFSKKPWRVIAEPSSSEGQGVLKSTIWDINHPIFPANSEVTFNVTFDVDSDASLGNKLLLKVVVTSENNVSRTDKTESQLELPVKYAIYMVVTSGESSIKYLNFTASEMTSKVIQHQYQFNNLGQRSFPVSVVFWIPVQINKVTIWDPPQVTFSQNLSSVCRTEQKSPSHSKFQDELERTPVLNCSVAVCKRIQCDIPSFNSKEIFNVTLQGNLLFDWYIETSHDHLLLVSTAEILFNDSAFALLPGQETFVKAQTETKVEPYKVHNPVPLIVGSSVGGLVLLALITAGLYKLGFFKRQYKDMMNEAAPQDGPPQ", "length": 1141, "header": "tr|A0A8I5Y8A4-1|A0A8I5Y8A4_RAT Computationally mapped isoform of Integrin subunit alpha M OS=Rattus norvegicus OX=10116 GN=Itgam PE=1 SV=1 CANONICAL=Q9QYE7-1" }, "locus": { "chromosome": "1", "start_pos": 182709048, "end_pos": 182661167, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000117515.1", "url": "https://www.ensembl.org/id/ENSRNOT00000117515.1" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000077846.1", "url": "https://www.ensembl.org/id/ENSRNOP00000077846.1" } ] } }, { "isoform_ac": "A0A8I5ZSN9-1", "url": "", "sequence": { "sequence": "CAGGAQEFLASCHGSNLDVEEPIVFREDAASFGQTVVQFGGSRLVVGAPLEAVAVNQTGRLYDCAPATGMCQPIVLRSPLEAVNMSLGLSLVTATNNAQLLACGPTAQRACVKNMYAKGSCLLLGSSLQFIQAVPASMPECPRQEMDIAFLIDGSGSINQRDFAQMKDFVKALMGEFASTSTLFSLMQYSNILKTHFTFTEFKNILDPQSLVDPIVQLQGLTYTATGIRTVVEELFHSKNGSRKSAKKILLVITDGQKYRDPLEYSDVIPAADKAGIIRYAIGVGDAFQEPTALKELNTIGSAPPQDHVFKVGNFAALRSIQRQLQEKIFAIEGTQSRSSSSFQHEMSQEGFSSALTSDGPVLGAVGSFSWSGGAFLYPPNTRPTFINMSQENVDMRDSYLGYSTAVAFWKGVHSLILGAPRHQHTGKVVIFTQEARHWRPKSEVRGTQGFGAYEEVAVDGSTDLVLIGAPHYYEQTRGGQVSVCPVPGVRGRWQCEATLHGEQGHPWGRFGVALTVLGDVNGDNLADVAIGAPGEEESRGAVYIFHGASRLEIMPSPSQRVTGSQLSLRLQYFGQSLSGGQDLTQDGLVDLAVGAQGHVLLLRSLPLLKVELSIRFAPMEVAKAVYQCWERTPTVLEAGEATVCLTVHKGSPDLLGNVQGSVRYDLALDPGRLISRAIFDETKNCTLTGRKTLGLGDHCETVKLLLPDCVEDAVSPIILRLNFSLVRDSASPRNLHPVLAVGSQDHITASLPFEKNCKQELLACEPRLPKKMNCIGILSVLVVGGSPELTVTVTVWNEGEDSYGTLVKFYYPAGLSYRRVTGTQQPHQYPLRLACEAEPAAQEDLRSSSCSINHPIFREGAKTTFMITFDVSYKAFLGDRLLLRAKASSENNKPDTNKTAFQLELPVKYTVYTLISRQEDSTNHVNFSSSHGGRRQEAAHRYRVNNLSPLKLAVRVNFWVPVLLNGVAVWDVTLSSPAQGVSCVSQMKPPQNPDFLTQIQRRSVLDCSIADCLHFRCDIPSLGIQDELDFILRGNLSFGWVSQTLQEKVLLVSEAEITFDTSVYSQLPGQEAFLRAQVETTLEEYVVYEPIFLVAGSSVGGLLLLALITVVLYKLGFFKRQYKEMLDGKAADPVTAGQADFGCETPPYLVS", "length": 1152, "header": "tr|A0A8I5ZSN9-1|A0A8I5ZSN9_RAT Computationally mapped isoform of Integrin subunit alpha D OS=Rattus norvegicus OX=10116 GN=Itgad PE=3 SV=1 CANONICAL=Q9QYE7-1" }, "locus": { "chromosome": "1", "start_pos": 182788086, "end_pos": 182761136, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000094184.1", "url": "https://www.ensembl.org/id/ENSRNOT00000094184.1" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000081657.1", "url": "https://www.ensembl.org/id/ENSRNOP00000081657.1" } ] } }, { "isoform_ac": "A0A8I5ZVY4-1", "url": "", "sequence": { "sequence": "TTMPFPPQSFLTLCHGFNLDTENPMTFQENARGFGQSVIQLGETRVVVAAPQEVKAVNQTGALYQCDYSTNRCDPIPLQVPPEAVNMSLGLSLAATTVPPQLLACGPTVHQNCKENTYVNGLCYLFGSNLLRKPQQFPEALRGCPQQESDIAFLIDGSGSINSIDFQKMKEFVSTVMDQFQKSKTLFSLMQYSDEFRTHFTFNDFKRNPDPKSHVRPIRQLNGRTKTASGIRKVVRELFQKINGARDNAAKILVVITDGEKFGDPLNYEDVIPEAEEAGIIRYVIGVGNAFHKPQSRRELDTIASKPAGDHVFQVDNFEALNTIRNQLQEKIFAIEGTQTGSTSSFEHEMSQEGFSAAITSNGPLLGSVGSFDWAGGAFLYPSKDKATFINTTRIDSDMNDAYLGYASAVISRNRVQSLVLGAPRYQHIGLVVMFKQNFGAWEPHTDIKGSQIGSYFGASLCSVDMDADGNTNLILIGAPHHYEKTRGGQVSVCPLPRGRARWQCEAILHGDQGHPWGRFGAALTVLGDVNGDKLTDVAIGAPGEQENQGAVYIFHGASVASISTPHSQRIAGARFSPGLQYFGQSLSGGKDLTMDGLMDLAVGAQGRLLLIRAQPVLRLEATMEFSPKNLARSVFACQEEVVKNKDAGEVRVCLHVRKNTKDRLREGDIQSTVTYDLALDPGRSVVRAFFDETKNGILRRIRVFGLTQKCETLKLILPDCVDNSVSPIILRLNYTLVGEPLRSSRDLRPVLAMEAQRIFTAMFPFEKNCGNDTICQDDLSITVSSIRVNTLVVGDSRDFDVSVTLRNDGEDSYGTKVTCYYPSGLSYRKVSASQNQFSKKPWRVIAEPSSSEGQGVLKSTIWDINHPIFPLWGAESQFLEVDKNCFPFSENNVSRTDKTESQLELPVKYAIYMVVTRCCSTPPVPSGWTPPALSLCSFAALCCSSGFFFLAFLFQNCSVAVCKRIQCDIPSFNSKEIFNVTLQGNLLFDWYIETSHDHLLLVSTAEILFNDSAFALLPGQETFVKAQTETKVEPYKVHNPVPLIVGSSVGGLVLLALITAGLYKLGFFKRQYKDMMNEAAPQDGPPQ", "length": 1088, "header": "tr|A0A8I5ZVY4-1|A0A8I5ZVY4_RAT Computationally mapped isoform of Integrin subunit alpha M OS=Rattus norvegicus OX=10116 GN=Itgam PE=1 SV=1 CANONICAL=Q9QYE7-1" }, "locus": { "chromosome": "1", "start_pos": 182709048, "end_pos": 182660679, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000111931.1", "url": "https://www.ensembl.org/id/ENSRNOT00000111931.1" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000082821.1", "url": "https://www.ensembl.org/id/ENSRNOP00000082821.1" } ] } }, { "isoform_ac": "A0A8I6A686-1", "url": "", "sequence": { "sequence": "MTLKFLLVTVLTLCHGFNLDTENPMTFQENARGFGQSVIQLGETRVVVAAPQEVKAVNQTGALYQCDYSTNRCDPIPLQVPPEAVNMSLGLSLAATTVPPQLLACGPTVHQNCKENTYVNGLCYLFGSNLLRKPQQFPEALRGCPQQESDIAFLIDGSGSINSIDFQKMKEFVSTVMDQFQKSKTLFSLMQYSDEFRTHFTFNDFKRNPDPKSHVRPIRQLNGRTKTASGIRKVVRELFQKINGARDNAAKILVVITDGEKFGDPLNYEDVIPEAEEAGIIRYVIGVGNAFHKPQSRRELDTIASKPAGDHVFQVDNFEALNTIRNQLQEKIFAIEGTQTGSTSSFEHEMSQEGFSAAITSNGPLLGSVGSFDWAGGAFLYPSKDKATFINTTRIDSDMNDAYLGYASAVISRNRVQSLVLGAPRYQHIGLVVMFKQNFGAWEPHTDIKGSQRIAGARFSPGLQYFGQSLSGGKDLTMDGLMDLAVGAQGRLLLIRAQPVLRLEATMEFSPKNLARSVFACQEEVVKNKDAGEVRVCLHVRKNTKDRLREGDIQSTVTYDLALDPGRSVVRAFFDETKNGILRRIRVFGLTQKCETLKLILPDCVDNSVSPIILRLNYTLVGEPLRSSRDLRPVLAMEAQRIFTAMFPFEKNCGNDTICQDDLSITVSSIRVNTLVVGDSRDFDVSVTLRNDGEDSYGTKVTCYYPSGLSYRKVSASQNQFSKKPWRVIAEPSSSEGQGVLKSTIWDINHPIFPANSEVTFNVTFDVDSDASLGNKLLLKVVVTSENNVSRTDKTESQLELPVKYAIYMVVTSGESSIKYLNFTASEMTSKVIQHQYQFNNLGQRSFPVSVVFWIPVQINKVTIWDPPQVTFSQNLSSVCRTEQKSPSHSKFQDELERTPVLNCSVAVCKRIQCDIPSFNSKEIFNVTLQGNLLFDWYIETSHDHLLLVSTAEILFNDSAFALLPGQETFVKAQTETKVEPYKVHNPVPLIVGSSVGGLVLLALITAGLYKLGFFKRQYKDMMNEAAPQDGPPQ", "length": 1034, "header": "tr|A0A8I6A686-1|A0A8I6A686_RAT Computationally mapped isoform of Integrin subunit alpha M OS=Rattus norvegicus OX=10116 GN=Itgam PE=1 SV=1 CANONICAL=Q9QYE7-1" }, "locus": { "chromosome": "1", "start_pos": 182709048, "end_pos": 182659176, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000093862.1", "url": "https://www.ensembl.org/id/ENSRNOT00000093862.1" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000088977.1", "url": "https://www.ensembl.org/id/ENSRNOP00000088977.1" } ] } }, { "isoform_ac": "F1M8G4-1", "url": "", "sequence": { "sequence": "VHCSVMAGGVVILLCGWVLASCHGSNLDVEEPIVFREDAASFGQTVVQFGGSRLVVGAPLEAVAVNQTGRLYDCAPATGMCQPIVLRSPLEAVNMSLGLSLVTATNNAQLLACGPTAQRACVKNMYAKGSCLLLGSSLQFIQAVPASMPECPRQEMDIAFLIDGSGSINQRDFAQMKDFVKALMGEFASTSTLFSLMQYSNILKTHFTFTEFKNILDPQSLVDPIVQLQGLTYTATGIRTVVEELFHSKNGSRKSAKKILLVITDGQKYRDPLEYSDVIPAADKAGIIRYAIGVGDAFQEPTALKELNTIGSAPPQDHVFKVGNFAALRSIQRQLQEKIFAIEGTQSRSSSSFQHEMSQEGFSSALTSDGPVLGAVGSFSWSGGAFLYPPNTRPTFINMSQENVDMRDSYLGYSTAVAFWKGVHSLILGAPRHQHTGKVVIFTQEARHWRPKSEVRGTQIGSYFGASLCSVDVDRDGSTDLVLIGAPHYYEQTRGGQVSVCPVPGVRGRWQCEATLHGEQGHPWGRFGVALTVLGDVNGDNLADVAIGAPGEEESRGAVYIFHGASRLEIMPSPSQRVTGSQLSLRLQYFGQSLSGGQDLTQDGLVDLAVGAQGHVLLLRSLPLLKVELSIRFAPMEVAKAVYQCWERTPTVLEAGEATVCLTVHKGSPDLLGNVQGSVRYDLALDPGRLISRAIFDETKNCTLTGRKTLGLGDHCETVKLLLPDCVEDAVSPIILRLNFSLVRDSASPRNLHPVLAVGSQDHITASLPFEKNCKQELLCEGDLGISFNFSGLQVLVVGGSPELTVTVTVWNEGEDSYGTLVKFYYPAGLSYRRVTGTQQPHQYPLRLACEAEPAAQEDLRSSSCSINHPIFREGAKTTFMITFDVSYKAFLGDRLLLRAKASSENNKPDTNKTAFQLELPVKYTVYTLISRQEDSTNHVNFSSSHGGRRQEAAHRYRVNNLSPLKLAVRVNFWVPVLLNGVAVWDVTLSSPAQGVSCVSQMKPPQNPDFLTQIQRRSVLDCSIADCLHFRCDIPSLGIQDELDFILRGNLSFGWVSQTLQEKVLLVSEAEITFDTSVYSQLPGQEAFLRAQVETTLEEYVVYEPIFLVAGSSVGGLLLLALITVVLYKLGFFKRQYKEMLDGKAADPVTAGQADFGCETPPYLVS", "length": 1166, "header": "tr|F1M8G4-1|F1M8G4_RAT Computationally mapped isoform of Integrin subunit alpha D OS=Rattus norvegicus OX=10116 GN=Itgad PE=3 SV=2 CANONICAL=Q9QYE7-1" }, "locus": { "chromosome": "1", "start_pos": 182788086, "end_pos": 182759770, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000085336.2", "url": "https://www.ensembl.org/id/ENSRNOT00000085336.2" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000071107.2", "url": "https://www.ensembl.org/id/ENSRNOP00000071107.2" } ] } }, { "isoform_ac": "G3V8L7-1", "url": "", "sequence": { "sequence": "TTMPFPPQSFLTLCHGFNLDTENPMTFQENARGFGQSVIQLGETRVVVAAPQEVKAVNQTGALYQCDYSTNRCDPIPLQVPPEAVNMSLGLSLAATTVPPQLLACGPTVHQNCKENTYVNGLCYLFGSNLLRKPQQFPEALRGCPQQESDIAFLIDGSGSINSIDFQKMKEFVSTVMDQFQKSKTLFSLMQYSDEFRTHFTFNDFKRNPDPKSHVRPIRQLNGRTKTASGIRKVVRELFQKINGARDNAAKILVVITDGEKFGDPLNYEDVIPEAEEAGIIRYVIGVGNAFHKPQSRRELDTIASKPAGDHVFQVDNFEALNTIRNQLQEKIFAIEGTQTGSTSSFEHEMSQEGFSAAITSNGPLLGSVGSFDWAGGAFLYPSKDKATFINTTRIDSDMNDAYLGYASAVISRNRVQSLVLGAPRYQHIGLVVMFKQNFGAWEPHTDIKGSQIGSYFGASLCSVDMDADGNTNLILIGAPHHYEKTRGGQVSVCPLPRGRARWQCEAILHGDQGHPWGRFGAALTVLGDVNGDKLTDVAIGAPGEQENQGAVYIFHGASVASISTPHSQRIAGARFSPGLQYFGQSLSGGKDLTMDGLMDLAVGAQGRLLLIRAQPVLRLEATMEFSPKNLARSVFACQEEVVKNKDAGEVRVCLHVRKNTKDRLREGDIQSTVTYDLALDPGRSVVRAFFDETKNGILRRIRVFGLTQKCETLKLILPDCVDNSVSPIILRLNYTLVGEPLRSSRDLRPVLAMEAQRIFTAMFPFEKNCGNDTICQDDLSITVSSIRVNTLVVGDSRDFDVSVTLRNDGEDSYGTKVTCYYPSGLSYRKVSASQNQFSKKPWRVIAEPSSSEGQGVLKSTIWDINHPIFPANSEVTFNVTFDVDSDASLGNKLLLKVVVTSENNVSRTDKTESQLELPVKYAIYMVVTSGESSIKYLNFTASEMTSKVIQHQYQFNNLGQRSFPVSVVFWIPVQINKVTIWDPPQVTFSQNLSSVCRTEQKSPSHSKFQDELERTPVLNCSVAVCKRIQCDIPSFNSKEIFNVTLQGNLLFDWYIETSHDHLLLVSTAEILFNDSAFALLPGQETFVKAQTETKVEPYKVHNPVPLIVGSSVGGLVLLALITAGLYKLGFFKRQYKDMMNEAAPQDGPPQ", "length": 1151, "header": "tr|G3V8L7-1|G3V8L7_RAT Computationally mapped isoform of Integrin subunit alpha M OS=Rattus norvegicus OX=10116 GN=Itgam PE=3 SV=2 CANONICAL=Q9QYE7-1" }, "locus": { "chromosome": "1", "start_pos": 182709048, "end_pos": 182660679, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000026748.5", "url": "https://www.ensembl.org/id/ENSRNOT00000026748.5" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000026748.4", "url": "https://www.ensembl.org/id/ENSRNOP00000026748.4" } ] } }, { "isoform_ac": "Q9QYE7-1", "url": "", "sequence": { "sequence": "MAGGVVILLCGWVLASCHGSNLDVEEPIVFREDAASFGQTVVQFGGSRLVVGAPLEAVAVNQTGRLYDCAPATGMCQPIVLRSPLEAVNMSLGLSLVTATNNAQLLACGPTAQRACVKNMYAKGSCLLLGSSLQFIQAVPASMPECPRQEMDIAFLIDGSGSINQRDFAQMKDFVKALMGEFASTSTLFSLMQYSNILKTHFTFTEFKNILDPQSLVDPIVQLQGLTYTATGIRTVMEELFHSKNGSRKSAKKILLVITDGQKYRDPLEYSDVIPAADKAGIIRYAIGVGDAFQEPTALKELNTIGSAPPQDHVFKVGNFAALRSIQRQLQEKIFAIEGTQSRSSSSFQHEMSQEGFSSALTSDGPVLGAVGSFSWSGGAFLYPPNTRPTFINMSQENVDMRDSYLGYSTAVAFWKGVHSLILGAPRHQHTGKVVIFTQEARHWRPKSEVRGTQIGSYFGASLCSVDVDRDGSTDLVLIGAPHYYEQTRGGQVSVFPVPGVRGRWQCEATLHGEQGHPWGRFGVALTVLGDVNGDNLADVAIGAPGEEESRGAVYIFHGASRLEIMPSPSQRVTGSQLSLRLQYFGQSLSGGQDLTQDGLVDLAVGAQGHVLLLRSLPLLKVELSIRFAPMEVAKAVYQCWERTPTVLEAGEATVCLTVHKGSPDLLGNVQGSVRYDLALDPGRLISRAIFDETKNCTLTGRKTLGLGDHCETVKLLLPDCVEDAVSPIILRLNFSLVRDSASPRNLHPVLAVGSQDHITASLPFEKNCKQELLCEGDLGISFNFSGLQVLVVGGSPELTVTVTVWNEGEDSYGTLVKFYYPAGLSYRRVTGTQQPHQYPLRLACEAEPAAQEDLRSSSCSINHPIFREGAKTTFMITFDVSYKAFLGDRLLLRAKASSENNKPDTNKTAFQLELPVKYTVYTLISRQEDSTNHVNFSSSHGGRRQEAAHRYRVNNLSPLKLAVRVNFWVPVLLNGVAVWDVTLSSPAQGVSCVSQMKPPQNPDFLTQIQRRSVLDCSIADCLHFRCDIPSLDIQDELDFILRGNLSFGWVSQTLQEKVLLVSEAEITFDTSVYSQLPGQEAFLRAQVETTLEEYVVYEPIFLVAGSSVGGLLLLALITVVLYKLGFFKRQYKEMLDGKAADPVTAGQADFGCETPPYLVS", "length": 1161, "header": "sp|Q9QYE7-1|ITAD_RAT Isoform 1 of Integrin alpha-D OS=Rattus norvegicus OX=10116 GN=Itgad PE=2 SV=1 CANONICAL=Q9QYE7-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "predicted", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 1045, "start_aa": "Asn", "end_pos": 1045, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1045", "evidence": [ { "id": "Q9QYE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9QYE7#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "predicted", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 245, "start_aa": "Asn", "end_pos": 245, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn245", "evidence": [ { "id": "Q9QYE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9QYE7#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "predicted", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 393, "start_aa": "Asn", "end_pos": 393, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn393", "evidence": [ { "id": "Q9QYE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9QYE7#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "predicted", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 61, "start_aa": "Asn", "end_pos": 61, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn61", "evidence": [ { "id": "Q9QYE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9QYE7#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "predicted", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 696, "start_aa": "Asn", "end_pos": 696, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn696", "evidence": [ { "id": "Q9QYE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9QYE7#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "predicted", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 734, "start_aa": "Asn", "end_pos": 734, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn734", "evidence": [ { "id": "Q9QYE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9QYE7#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "predicted", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 784, "start_aa": "Asn", "end_pos": 784, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn784", "evidence": [ { "id": "Q9QYE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9QYE7#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "predicted", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 89, "start_aa": "Asn", "end_pos": 89, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn89", "evidence": [ { "id": "Q9QYE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9QYE7#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "predicted", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 907, "start_aa": "Asn", "end_pos": 907, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn907", "evidence": [ { "id": "Q9QYE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9QYE7#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "predicted", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 936, "start_aa": "Asn", "end_pos": 936, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn936", "evidence": [ { "id": "Q9QYE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q9QYE7#ptm_processing" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Anti-CD11d monoclonal antibody treatment for rat spinal cord compression injury.", "journal": "Experimental neurology", "date": "2012", "authors": "Hurtado A, Marcillo A, Frydel B, Bunge MB, Bramlett HM, Dietrich WD", "evidence": [ { "database": "RefSeq", "id": "NP_113879", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_113879" } ], "reference": [ { "type": "PubMed", "id": "21145887", "url": "https://glygen.org/publication/PubMed/21145887" } ] }, { "title": "Inflammatory phenotyping identifies CD11d as a gene markedly induced in white adipose tissue in obese rodents and women.", "journal": "The Journal of nutrition", "date": "2011", "authors": "Thomas AP, Dunn TN, Oort PJ, Grino M, Adams SH", "evidence": [ { "database": "RefSeq", "id": "NP_113879", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_113879" } ], "reference": [ { "type": "PubMed", "id": "21508205", "url": "https://glygen.org/publication/PubMed/21508205" } ] }, { "title": "Natural recovery from antiglomerular basement membrane glomerulonephritis is associated with glomeruli-infiltrating CD8alpha+CD11c+MHC class II+ cells.", "journal": "American journal of nephrology", "date": "2011", "authors": "Zhou C, Robertson J, Wu J, Bartkowiak T, Parker K, McMahon J, Lou YH", "evidence": [ { "database": "RefSeq", "id": "NP_113879", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_113879" } ], "reference": [ { "type": "PubMed", "id": "22068125", "url": "https://glygen.org/publication/PubMed/22068125" } ] } ], "pathway": [ { "id": "rno:64350", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:64350", "resource": "KEGG Pathway" }, { "id": "R-RNO-216083", "name": "Integrin cell surface interactions", "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-216083", "resource": "Reactome", "description": "Integrin cell surface interactions" } ], "orthologs": [ { "uniprot_canonical_ac": "Q13349-1", "protein_name": "Integrin alpha-D", "gene_name": "ITGAD", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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