{
    "uniprot_canonical_ac": "Q9ET62-1",
    "uniprot_ac": "Q9ET62",
    "uniprot_id": "IMPG1_RAT",
    "mass": {
        "chemical_mass": 89950.0,
        "monoisotopic_mass": 89950.0
    },
    "refseq": {
        "ac": "NP_076448",
        "name": "interphotoreceptor matrix proteoglycan 1 precursor",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_076448"
    },
    "gene_names": [
        {
            "name": "Impg1",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/Q9ET62",
            "id": "Q9ET62"
        },
        {
            "name": "Impg1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_076448",
            "id": "NP_076448"
        },
        {
            "name": "Mlgapc",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_076448",
            "id": "NP_076448"
        },
        {
            "name": "Mlgapc",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/Q9ET62",
            "id": "Q9ET62"
        }
    ],
    "protein_names": [
        {
            "name": "Interphotoreceptor matrix proteoglycan 1",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "Q9ET62"
        },
        {
            "name": "Mucin-like glycoprotein associated with photoreceptor cells",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q9ET62"
        },
        {
            "name": "Sialoprotein associated with cones and rods",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q9ET62"
        },
        {
            "name": "interphotoreceptor matrix proteoglycan 1 precursor",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_076448",
            "id": "NP_076448"
        },
        {
            "name": "sialoprotein associated with cones and rods; mucin-like glycoprotein associated with photoreceptor cells",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_076448",
            "id": "NP_076448"
        }
    ],
    "function": [
        {
            "annotation": "Chondroitin sulfate-, heparin- and hyaluronan-binding protein (By similarity). May serve to form a basic macromolecular scaffold comprising the insoluble interphotoreceptor matrix (By similarity).",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q9ET62",
                    "url": "https://www.uniprot.org/uniprot/Q9ET62#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "Q8JIR8",
                    "url": "https://www.uniprot.org/uniprot/Q8JIR8#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "Q17R60",
                    "url": "https://www.uniprot.org/uniprot/Q17R60#function"
                }
            ]
        }
    ],
    "disease": [
        {
            "disease_id": "DOID:0050661",
            "recommended_name": {
                "id": "DOID:0050661",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0050661",
                "name": "vitelliform macular dystrophy",
                "description": "A macular degeneration that it is characterized by the disruption of cells in a small area near the center of the retina, the macula and may cause progressive vision loss."
            },
            "synonyms": [
                {
                    "id": "DOID:0050661",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0050661",
                    "name": "Best disease",
                    "description": ""
                },
                {
                    "id": "DOID:0050661",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0050661",
                    "name": "Best macular dystrophy",
                    "description": ""
                },
                {
                    "id": "DOID:0050661",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0050661",
                    "name": "juvenile-onset vitelliform macular dystrophy",
                    "description": ""
                },
                {
                    "id": "MONDO:0014508",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0014508",
                    "name": "vitelliform macular dystrophy 4",
                    "description": "Any vitelliform macular dystrophy in which the cause of the disease is a mutation in the IMPG1 gene."
                },
                {
                    "id": "MONDO:0014508",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0014508",
                    "name": "IMPG1 vitelliform macular dystrophy",
                    "description": ""
                },
                {
                    "id": "MONDO:0014508",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0014508",
                    "name": "macular dystrophy, vitelliform, 4",
                    "description": ""
                },
                {
                    "id": "MONDO:0014508",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0014508",
                    "name": "macular dystrophy, vitelliform, type 4",
                    "description": ""
                },
                {
                    "id": "MONDO:0014508",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0014508",
                    "name": "vitelliform macular dystrophy caused by mutation in IMPG1",
                    "description": ""
                },
                {
                    "id": "MONDO:0014508",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0014508",
                    "name": "VMD4",
                    "description": ""
                },
                {
                    "id": "MONDO:0007933",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007933",
                    "name": "vitelliform macular dystrophy 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0007933",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007933",
                    "name": "VMD1",
                    "description": ""
                },
                {
                    "id": "MONDO:0007933",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007933",
                    "name": "macular dystrophy, atypical vitelliform",
                    "description": ""
                },
                {
                    "id": "MONDO:0007933",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007933",
                    "name": "macular dystrophy, vitelliform, 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0007933",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007933",
                    "name": "vitelliform macular dystrophy, atypical",
                    "description": ""
                },
                {
                    "id": "MONDO:0007931",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007931",
                    "name": "vitelliform macular dystrophy 2",
                    "description": "Best vitelliform macular dystrophy (BVMD) is a genetic macular dystrophy characterized by loss of central visual acuity, metamorphopsia and a decrease in the Arden ratio secondary to an egg yolk-like lesion located in the foveal or parafoveal region."
                },
                {
                    "id": "MONDO:0007931",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007931",
                    "name": "BEST1 retinopathy",
                    "description": ""
                },
                {
                    "id": "MONDO:0007931",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007931",
                    "name": "BMD",
                    "description": ""
                },
                {
                    "id": "MONDO:0007931",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007931",
                    "name": "BVMD",
                    "description": ""
                },
                {
                    "id": "MONDO:0007931",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007931",
                    "name": "Best disease",
                    "description": ""
                },
                {
                    "id": "MONDO:0007931",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007931",
                    "name": "Best macular dystrophy",
                    "description": ""
                },
                {
                    "id": "MONDO:0007931",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007931",
                    "name": "early-onset vitelliform macular dystrophy",
                    "description": ""
                },
                {
                    "id": "MONDO:0007931",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007931",
                    "name": "juvenile-onset vitelliform macular dystrophy",
                    "description": ""
                },
                {
                    "id": "MONDO:0007931",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007931",
                    "name": "macular degeneration, polymorphic vitelline",
                    "description": ""
                },
                {
                    "id": "MONDO:0007931",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007931",
                    "name": "macular dystrophy, vitelliform, type 2",
                    "description": ""
                },
                {
                    "id": "MONDO:0007931",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007931",
                    "name": "polymorphic vitelline macular degeneration",
                    "description": ""
                },
                {
                    "id": "MONDO:0007931",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007931",
                    "name": "vitelliform macular dystrophy type 2",
                    "description": ""
                },
                {
                    "id": "MONDO:0007931",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007931",
                    "name": "vitelliform macular dystrophy, early-onset",
                    "description": ""
                },
                {
                    "id": "MONDO:0007931",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007931",
                    "name": "vitelliform macular dystrophy, juvenile-onset",
                    "description": ""
                },
                {
                    "id": "MONDO:0007931",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007931",
                    "name": "vitelliform macular dystrophy, type 2",
                    "description": ""
                },
                {
                    "id": "MONDO:0007931",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007931",
                    "name": "Best vitelliform macular dystrophy, multifocal",
                    "description": ""
                },
                {
                    "id": "MONDO:0007931",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007931",
                    "name": "VMD2",
                    "description": ""
                },
                {
                    "id": "MONDO:0007931",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007931",
                    "name": "macular Degeneration, polymorphic vitelline",
                    "description": ""
                },
                {
                    "id": "MONDO:0007931",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007931",
                    "name": "macular dystrophy, vitelliform, 2",
                    "description": ""
                },
                {
                    "id": "MONDO:0024561",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0024561",
                    "name": "vitelliform macular dystrophy 3",
                    "description": "Any vitelliform macular dystrophy in which the cause of the disease is a mutation in the PRPH2 gene."
                },
                {
                    "id": "MONDO:0024561",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0024561",
                    "name": "PRPH2 vitelliform macular dystrophy",
                    "description": ""
                },
                {
                    "id": "MONDO:0024561",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0024561",
                    "name": "vitelliform macular dystrophy caused by mutation in PRPH2",
                    "description": ""
                },
                {
                    "id": "MONDO:0024561",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0024561",
                    "name": "VMD3",
                    "description": ""
                },
                {
                    "id": "MONDO:0024561",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0024561",
                    "name": "foveomacular dystrophy, adult-onset",
                    "description": ""
                },
                {
                    "id": "MONDO:0024561",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0024561",
                    "name": "foveomacular dystrophy, adult-onset, with or without choroidal neovascularization",
                    "description": ""
                },
                {
                    "id": "MONDO:0024561",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0024561",
                    "name": "macular dystrophy, vitelliform, 3",
                    "description": ""
                },
                {
                    "id": "MONDO:0024561",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0024561",
                    "name": "vitelliform macular dystrophy, adult-onset",
                    "description": ""
                },
                {
                    "id": "MONDO:0014509",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0014509",
                    "name": "vitelliform macular dystrophy 5",
                    "description": "Any vitelliform macular dystrophy in which the cause of the disease is a mutation in the IMPG2 gene."
                },
                {
                    "id": "MONDO:0014509",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0014509",
                    "name": "IMPG2 vitelliform macular dystrophy",
                    "description": ""
                },
                {
                    "id": "MONDO:0014509",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0014509",
                    "name": "macular dystrophy, vitelliform, 5",
                    "description": ""
                },
                {
                    "id": "MONDO:0014509",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0014509",
                    "name": "macular dystrophy, vitelliform, type 5",
                    "description": ""
                },
                {
                    "id": "MONDO:0014509",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0014509",
                    "name": "vitelliform macular dystrophy caused by mutation in IMPG2",
                    "description": ""
                },
                {
                    "id": "MONDO:0014509",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0014509",
                    "name": "VMD5",
                    "description": ""
                },
                {
                    "id": "MIM:616151",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/616151",
                    "name": "Macular dystrophy, vitelliform, 4",
                    "description": "Macular dystrophy, vitelliform, 4"
                },
                {
                    "id": "MIM:153700",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/153700",
                    "name": "Macular dystrophy, vitelliform, 2",
                    "description": "Macular dystrophy, vitelliform, 2"
                },
                {
                    "id": "MIM:608161",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/608161",
                    "name": "Macular dystrophy, vitelliform, 3",
                    "description": "Macular dystrophy, vitelliform, 3"
                },
                {
                    "id": "MIM:616152",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/616152",
                    "name": "Macular dystrophy, vitelliform, 5",
                    "description": "Macular dystrophy, vitelliform, 5"
                }
            ],
            "evidence": [
                {
                    "id": "0050661",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050661"
                }
            ]
        },
        {
            "disease_id": "DOID:10584",
            "recommended_name": {
                "id": "DOID:10584",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:10584",
                "name": "retinitis pigmentosa",
                "description": "A retinal degeneration characterized by the gradual deterioration of the photoreceptors or the retinal pigment epithelium of the retina leading to progressive sight loss."
            },
            "synonyms": [
                {
                    "id": "DOID:10584",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10584",
                    "name": "pericentral pigmentary retinopathy",
                    "description": ""
                },
                {
                    "id": "MONDO:0019200",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0019200",
                    "name": "retinitis pigmentosa",
                    "description": "Retinitis pigmentosa (RP) is an inherited retinal dystrophy leading to progressive loss of the photoreceptors and retinal pigment epithelium and resulting in blindness usually after several decades."
                },
                {
                    "id": "MONDO:0019200",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0019200",
                    "name": "retinitis pigmentosa",
                    "description": ""
                },
                {
                    "id": "MONDO:0019200",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0019200",
                    "name": "pericentral pigmentary retinopathy",
                    "description": ""
                },
                {
                    "id": "MONDO:0019200",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0019200",
                    "name": "Rod-cone dystrophy",
                    "description": ""
                },
                {
                    "id": "MIM:268000",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/268000",
                    "name": "Retinitis pigmentosa",
                    "description": "Retinitis pigmentosa"
                }
            ],
            "evidence": [
                {
                    "id": "10584",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:10584"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q9ET62",
                    "url": "https://www.uniprot.org/uniprot/Q9ET62"
                }
            ],
            "common_name": "Rat"
        }
    ],
    "gene": [
        {
            "name": "Impg1",
            "url": "https://www.uniprot.org/uniprot/Q9ET62",
            "locus": {
                "chromosome": "8",
                "start_pos": 81243624,
                "end_pos": 81389722,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSRNOG00000012479",
                        "url": "https://www.ensembl.org/id/ENSRNOG00000012479"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSRNOG00000012479",
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000012479",
            "database": "Bgee",
            "categories": [
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            ]
        },
        {
            "id": "66014",
            "url": "https://www.ncbi.nlm.nih.gov/gene/66014",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR000082",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000082",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR036364",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036364",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR039861",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR039861",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "rno:66014",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:66014",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "SECVMNE",
            "url": "https://omabrowser.org/oma/group/SECVMNE/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "4244504at2759",
            "url": "http://www.orthodb.org/?query=4244504at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR12199",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12199",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR12199:SF3",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12199:SF3",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF01390",
            "url": "http://pfam.xfam.org/family/PF01390",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_Q9ET62",
            "url": "http://purl.obolibrary.org/obo/PR_Q9ET62",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "NP_076448",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_076448",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "620499",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=620499",
            "database": "RGD",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "A0A8I6ALU8",
            "url": "https://www.uniprot.org/uniprot/A0A8I6ALU8",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8I6ALU8-1",
            "url": "https://www.uniprot.org/uniprot/A0A8I6ALU8-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "F1LQ01",
            "url": "https://www.uniprot.org/uniprot/F1LQ01",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "F1LQ01-1",
            "url": "https://www.uniprot.org/uniprot/F1LQ01-1",
            "database": "UniProtKB",
            "categories": [
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            ]
        },
        {
            "id": "Q9ET62",
            "url": "https://www.uniprot.org/uniprot/Q9ET62",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q9ET62-1",
            "url": "https://www.uniprot.org/uniprot/Q9ET62-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MNLEIKHAILVLWIFLQVQGIKDTSTKTHSSGTKNIDKAPRIETTESTSAVHKASTMKRLFAVAKLRNKRSALFPAVNICPRESLRQILESLQEYYRLRVCQEIVWEAYRIFLDRVPDTEEYQDWVSLCQKETFCLFDIGKNFSNSQEHLDLLQQRIFQRSFSGRKDDMSPIEILGVPTTAPVLPIDVSSMSLRPFPLPPDDTDLKEVTIKDIQTPIAIRRAELESKPEPTHVTEISSEEKVEFSISLPNHRFKAELTNSRSPYYQELVGQSQLQLQKIFKKLPGFGEIRVLGFRPKKEEDGSSSTEIQLMAIFKRDHAESKGPESDLLSLDSNKIERERIHHGAIEDKQPEAYLTAADLKKLIIRLLDGDQPLVGGTVPFSDEVTEPLFRPVTQSELPKPLTDVTEDVTLSPELPFSEPRLESVDIYGPYLPDSSWSRPVTASTSGVGNLPSFTPSIFALDDQSSPPLMATGPTAFIPTLTLPISDYSTVRQWPLEVSHWPESSSDRELSTTSSHDTIRDLDEMDVSDTPALSEIAELSGYDSAPDRFLEMTTPIPTLQYVTXSSETIAAKGHELVVFFSLRVANMPFSYDLFNKSSLEYQALEQRFTDLLVPYLRSNLTGFKQLEILSFRNGSVIVNSKVRFAKAVPYNLTQAVRGVLEDLRSTAAQELNLEIESYSLDIEPADQADPCKFLDCGKFAQCIKNELTEEAECRCRQGHESHGTLEYQELNLCPPGKTCEASQGQATPCRPPDHSTNQARQPSVKKLQRQQNKVVKKRNSELSATDFEELDDQDWEGN",
        "length": 798,
        "header": "sp|Q9ET62-1|IMPG1_RAT Isoform 1 of Interphotoreceptor matrix proteoglycan 1  OS=Rattus norvegicus OX=10116 GN=Impg1 PE=2 SV=1 CANONICAL=Q9ET62-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A8I6ALU8-1",
            "url": "",
            "sequence": {
                "sequence": "MNLEIKHAILVLWIFLQVQGIKDTSTKTHSSGTKNIDKAPRIETTESTSAVHKASTMKRLFAVAKLRNKRSALFPAVNICLRESLRQILESLQEYYRLRVCQEIVWEAYRIFLDRVPDTEEYQDWVSLCQKETFCLFDIGKNFSNSQEHLDLLQQVNLCNVLGEADDMSPIEILGVPTTAPVLPIDVSSMSLRPFPLPPDDTDLKEVTIKDIQTPIAIRRAELESKPEPTHVTEISSEEKVEFSISLPNHRFKAELTNSRSPYYQELVGQSQLQLQKIFKKLPGFGEIRVLGFRPKKEEDGSSSTEIQLMAIFKRDHAESKGPESDLLSLDSNKIERERIHHGAIEDKQPEAYLTAADLKKLIIRLLDGDQPLVGGTVPFSDEVTEPLFRPVTQSELPKPLTDVTEDVTLSPELPFSEPRLESVDRDGPDLPDSSWSLPVTASTSGVGNLPSFTPSIFALDDQSSPPLMATGPTAFIPTLTLPTLDYSTVRQWPLEVSHWPESSSDRELTTSSHDTIRDLDEMDVSDTPALSEIAELSGYDSAPDRFLEMTTPIPTLQYVTTSSETIAAKGHELVVFFSLRVANMPFSYDLFNKSSLEYQALEQRFTDLLVPYLRSNLTGFKQLEILSFRNGSVIVNSKVRFAKAVPYNLTQAVRGVLEDLRSTAAQELNLEIESFSLNIEPADQADPCKFLDCGKFAQCIKNELTEEAECRCRQGHESHGTLEYQELNLCPPGKTCEASQGQATPCRPPDHSTNQARQPSVKKLQRQQNKVVKKRNSELSATDFEELDDQDWEGN",
                "length": 796,
                "header": "tr|A0A8I6ALU8-1|IMPG1_RAT Computationally mapped isoform of Interphotoreceptor matrix proteoglycan 1  OS=Rattus norvegicus OX=10116 GN=Impg1 PE=2 SV=1 CANONICAL=Q9ET62-1"
            },
            "locus": {
                "chromosome": "8",
                "start_pos": 81389569,
                "end_pos": 81244628,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000098739.1",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000098739.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000094549.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000094549.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "F1LQ01-1",
            "url": "",
            "sequence": {
                "sequence": "MNLEIKHAILVLWIFLQVQGIKDTSTKTHSSGTKNIDKAPRIETTESTSAVHKASTMKRLFAVAKLRNKRSALFPAVNICLRESLRQILESLQEYYRLRVCQEIVWEAYRIFLDRVPDTEEYQDWVSLCQKETFCLFDIGKNFSNSQEHLDLLQQRIKQRSFSGRKDDMSPIEILGVPTTAPVLPIDVSSMSLRPFPLPPDDTDLKEVTIKDIQTPIAIRRAELESKPEPTHVTEISSEEKVEFSISLPNHRFKAELTNSRSPYYQELVGQSQLQLQKIFKKLPGFGEIRVLGFRPKKEEDGSSSTEIQLMAIFKRDHAESKGPESDLLSLDSNKIERERIHHGAIEDKQPEAYLTAADLKKLIIRLLDGDQPLVGGTVPFSDEVTEPLFRPVTQSELPKPLTDVTEDVTLSPELPFSEPRLESVDRDGPDLPDSSWSLPVTASTSGVGNLPSFTPSIFALDDQSSPPLMATGPTAFIPTLTLPTLDYSTVRQWPLEVSHWPESSSDRELTTSSHDTIRDLDEMDVSDTPALSEIAELSGYDSAPDRFLEMTTPIPTLQYVTTSSETIAAKGHELVVFFSLRVANMPFSYDLFNKSSLEYQALEQRFTDLLVPYLRSNLTGFKQLEILSFRNGSVIVNSKVRFAKAVPYNLTQAVRGVLEDLRSTAAQELNLEIESFSLNIEPADQADPCKFLDCGKFAQCIKNELTEEAECRCRQGHESHGTLEYQELNLCPPGKTCEASQGQATPCRPPDHSTNQARQPSVKKLQRQQNKVVKKRNSELSATDFEELDDQDWEGN",
                "length": 797,
                "header": "tr|F1LQ01-1|IMPG1_RAT Computationally mapped isoform of Interphotoreceptor matrix proteoglycan 1  OS=Rattus norvegicus OX=10116 GN=Impg1 PE=2 SV=1 CANONICAL=Q9ET62-1"
            },
            "locus": {
                "chromosome": "8",
                "start_pos": 81389569,
                "end_pos": 81244628,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000017048.4",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000017048.4"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000017048.3",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000017048.3"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q9ET62-1",
            "url": "",
            "sequence": {
                "sequence": "MNLEIKHAILVLWIFLQVQGIKDTSTKTHSSGTKNIDKAPRIETTESTSAVHKASTMKRLFAVAKLRNKRSALFPAVNICPRESLRQILESLQEYYRLRVCQEIVWEAYRIFLDRVPDTEEYQDWVSLCQKETFCLFDIGKNFSNSQEHLDLLQQRIFQRSFSGRKDDMSPIEILGVPTTAPVLPIDVSSMSLRPFPLPPDDTDLKEVTIKDIQTPIAIRRAELESKPEPTHVTEISSEEKVEFSISLPNHRFKAELTNSRSPYYQELVGQSQLQLQKIFKKLPGFGEIRVLGFRPKKEEDGSSSTEIQLMAIFKRDHAESKGPESDLLSLDSNKIERERIHHGAIEDKQPEAYLTAADLKKLIIRLLDGDQPLVGGTVPFSDEVTEPLFRPVTQSELPKPLTDVTEDVTLSPELPFSEPRLESVDIYGPYLPDSSWSRPVTASTSGVGNLPSFTPSIFALDDQSSPPLMATGPTAFIPTLTLPISDYSTVRQWPLEVSHWPESSSDRELSTTSSHDTIRDLDEMDVSDTPALSEIAELSGYDSAPDRFLEMTTPIPTLQYVTXSSETIAAKGHELVVFFSLRVANMPFSYDLFNKSSLEYQALEQRFTDLLVPYLRSNLTGFKQLEILSFRNGSVIVNSKVRFAKAVPYNLTQAVRGVLEDLRSTAAQELNLEIESYSLDIEPADQADPCKFLDCGKFAQCIKNELTEEAECRCRQGHESHGTLEYQELNLCPPGKTCEASQGQATPCRPPDHSTNQARQPSVKKLQRQQNKVVKKRNSELSATDFEELDDQDWEGN",
                "length": 798,
                "header": "sp|Q9ET62-1|IMPG1_RAT Isoform 1 of Interphotoreceptor matrix proteoglycan 1  OS=Rattus norvegicus OX=10116 GN=Impg1 PE=2 SV=1 CANONICAL=Q9ET62-1"
            },
            "locus": {}
        }
    ],
    "glycosylation": [
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 142,
            "start_aa": "Asn",
            "end_pos": 142,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn142",
            "evidence": [
                {
                    "id": "Q9ET62",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/Q9ET62#ptm_processing"
                }
            ]
        },
        {
            "glytoucan_ac": "",
            "type": "O-linked",
            "subtype": "O-GalNAcylation",
            "site_category": "predicted",
            "site_seq": "T",
            "relation": "attached",
            "comment": "O-linked (GalNAc...) threonine O-GalNAcylation",
            "start_pos": 442,
            "start_aa": "Thr",
            "end_pos": 442,
            "end_aa": "Thr",
            "residue": "Thr",
            "site_lbl": "Thr442",
            "evidence": [
                {
                    "id": "Q9ET62",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/Q9ET62#ptm_processing"
                }
            ]
        },
        {
            "glytoucan_ac": "",
            "type": "O-linked",
            "subtype": "O-GalNAcylation",
            "site_category": "predicted",
            "site_seq": "T",
            "relation": "attached",
            "comment": "O-linked (GalNAc...) threonine O-GalNAcylation",
            "start_pos": 445,
            "start_aa": "Thr",
            "end_pos": 445,
            "end_aa": "Thr",
            "residue": "Thr",
            "site_lbl": "Thr445",
            "evidence": [
                {
                    "id": "Q9ET62",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/Q9ET62#ptm_processing"
                }
            ]
        },
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 595,
            "start_aa": "Asn",
            "end_pos": 595,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn595",
            "evidence": [
                {
                    "id": "Q9ET62",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/Q9ET62#ptm_processing"
                }
            ]
        },
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 619,
            "start_aa": "Asn",
            "end_pos": 619,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn619",
            "evidence": [
                {
                    "id": "Q9ET62",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/Q9ET62#ptm_processing"
                }
            ]
        },
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 633,
            "start_aa": "Asn",
            "end_pos": 633,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn633",
            "evidence": [
                {
                    "id": "Q9ET62",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/Q9ET62#ptm_processing"
                }
            ]
        },
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 651,
            "start_aa": "Asn",
            "end_pos": 651,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn651",
            "evidence": [
                {
                    "id": "Q9ET62",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/Q9ET62#ptm_processing"
                }
            ]
        }
    ],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [
        "glycoprotein",
        "glycoprotein_predicted"
    ],
    "publication": [
        {
            "title": "Mucin-like glycoprotein associated with photoreceptor cells in the postnatal developing rat retina.",
            "journal": "Ophthalmic Res.",
            "date": "2002",
            "authors": "Uehara F, Ohba N, Ozawa M",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q9ET62",
                    "url": "https://www.uniprot.org/uniprot/Q9ET62"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "11914607",
                    "url": "https://glygen.org/publication/PubMed/11914607"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "rno:66014",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:66014",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q17R60-1",
            "protein_name": "Interphotoreceptor matrix proteoglycan 1",
            "gene_name": "IMPG1",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MYLETRRAIFVFWIFLQVQGTKDISINIYHSETKDIDNPPRNETTESTEKMYKMSTMRRIFDLAKHRTKRSAFFPTGVKVCPQESMKQILDSLQAYYRLRVCQEAVWEAYRIFLDRIPDTGEYQDWVSICQQETFCLFDIGKNFSNSQEHLDLLQQRIKQRSFPDRKDEISAEKTLGEPGETIVISTDVANVSLGPFPLTPDDTLLNEILDNTLNDTKMPTTERETEFAVLEEQRVELSVSLVNQKFKAELADSQSPYYQELAGKSQLQMQKIFKKLPGFKKIHVLGFRPKKEKDGSSSTEMQLTAIFKRHSAEAKSPASDLLSFDSNKIESEEVYHGTMEEDKQPEIYLTATDLKRLISKALEEEQSLDVGTIQFTDEIAGSLPAFGPDTQSELPTSFAVITEDATLSPELPPVEPQLETVDGAEHGLPDTSWSPPAMASTSLSEAPPFFMASSIFSLTDQGTTDTMATDQTMLVPGLTIPTSDYSAISQLALGISHPPASSDDSRSSAGGEDMVRHLDEMDLSDTPAPSEVPELSEYVSVPDHFLEDTTPVSALQYITTSSMTIAPKGRELVVFFSLRVANMAFSNDLFNKSSLEYRALEQQFTQLLVPYLRSNLTGFKQLEILNFRNGSVIVNSKMKFAKSVPYNLTKAVHGVLEDFRSAAAQQLHLEIDSYSLNIEPADQADPCKFLACGEFAQCVKNERTEEAECRCKPGYDSQGSLDGLEPGLCGPGTKECEVLQGKGAPCRLPDHSENQAYKTSVKKFQNQQNNKVISKRNSELLTVEYEEFNHQDWEGN",
                "length": 797
            },
            "evidence": [
                {
                    "id": "45230595",
                    "url": "http://www.informatics.jax.org/homology/45230595",
                    "database": "MGI"
                }
            ],
            "common_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q8R1W8-1",
            "protein_name": "Interphotoreceptor matrix proteoglycan 1",
            "gene_name": "Impg1",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MNLQIKHAIFVLGIFLQVQGIKDTSIKIFSSEIKNIDKTPRIETIESTSTVHKVSTMKRIFDLPKLRTKRSALFPAANICPQESLRQILASLQEYYRLRVCQEVVWEAYRIFLDRIPDTEEYQDWVSLCQKETFCLFDIGKNFSNSQEHLDLLQQRIKQRSFPGRKDETASMETLEAPTEAPVVPTDVSRMSLGPFPLPSDDTDLKEILSVTLKDIQKPTTESKTEPIHVSEFSSEEKVEFSISLPNHRFKAELTNSGSPYYQELVGQSQLQLQKIFKKLPGFGEIRVLGFRPKKEEDGSSSTEIQLMAIFKRDHAEAKSPDSHLLSLDSNKIESERIHHGVIEDKQPETYLTATDLKKLIIQLLDGDLSLVEGKIPFGDEVTGTLFRPVTEPDLPKPLADVTEDATLSPELPFVEPRLEAVDREGSELPGMSSKDSSWSPPVSASISRSENLPSFTPSIFSLDAQSPPPLMTTGPTALIPKPTLPTIDYSTIRQLPLESSHWPASSSDRELITSSHDTIRDLDGMDVSDTPALSEISELSGYDSASGQFLEMTTPIPTVRFITTSSETIATKGQELVVFFSLRVANMPFSYDLFNKSSLEYQALEQRFTDLLVPYLRSNLTGFKQLEILSFRNGSVIVNSKVRFAKAVPYNLTQAVRGVLEDLRSTAAQGLNLEIESYSLDIEPADQADPCKLLDCGKFAQCVKNEWTEEAECRCRQGHESHGTLDYQTLNLCPPGKTCVAGREQATPCRPPDHSTNQAQEPGVKKLRQQNKVVKKRNSKLSAIGFEEFEDQDWEGN",
                "length": 798
            },
            "evidence": [
                {
                    "id": "45230595",
                    "url": "http://www.informatics.jax.org/homology/45230595",
                    "database": "MGI"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Cellular Component",
                "total": 5,
                "go_terms": [
                    {
                        "name": "interphotoreceptor matrix",
                        "id": "GO:0033165",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033165",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q9ET62",
                                "url": "https://www.uniprot.org/uniprot/Q9ET62"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "extracellular region",
                        "id": "GO:0005576",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q9ET62",
                                "url": "https://www.uniprot.org/uniprot/Q9ET62"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "photoreceptor inner segment",
                        "id": "GO:0001917",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001917",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q9ET62",
                                "url": "https://www.uniprot.org/uniprot/Q9ET62"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "photoreceptor outer segment",
                        "id": "GO:0001750",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001750",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q9ET62",
                                "url": "https://www.uniprot.org/uniprot/Q9ET62"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cell projection",
                        "id": "GO:0042995",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042995",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q9ET62",
                                "url": "https://www.uniprot.org/uniprot/Q9ET62"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 3,
                "go_terms": [
                    {
                        "name": "heparin binding",
                        "id": "GO:0008201",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008201",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q9ET62",
                                "url": "https://www.uniprot.org/uniprot/Q9ET62"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "chondroitin sulfate binding",
                        "id": "GO:0035374",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035374",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q9ET62",
                                "url": "https://www.uniprot.org/uniprot/Q9ET62"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "hyaluronic acid binding",
                        "id": "GO:0005540",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005540",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q9ET62",
                                "url": "https://www.uniprot.org/uniprot/Q9ET62"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 2,
                "go_terms": [
                    {
                        "name": "extracellular matrix organization",
                        "id": "GO:0030198",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q9ET62",
                                "url": "https://www.uniprot.org/uniprot/Q9ET62"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "visual perception",
                        "id": "GO:0007601",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007601",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q9ET62",
                                "url": "https://www.uniprot.org/uniprot/Q9ET62"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 142,
            "end_pos": 144,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 595,
            "end_pos": 597,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 619,
            "end_pos": 621,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 633,
            "end_pos": 635,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 651,
            "end_pos": 653,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [
        {
            "annotation": "Highly glycosylated (N- and O-linked carbohydrates and sialic acid).",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q9ET62",
                    "url": "https://www.uniprot.org/uniprot/Q9ET62"
                },
                {
                    "database": "PubMed",
                    "id": "Q17R60",
                    "url": "https://glygen.org/publication/PubMed/Q17R60"
                }
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