{
    "uniprot_canonical_ac": "Q9D9Z1-1",
    "uniprot_ac": "Q9D9Z1",
    "uniprot_id": "SKAP_MOUSE",
    "mass": {
        "chemical_mass": 34728.0,
        "monoisotopic_mass": 34728.0
    },
    "refseq": {
        "ac": "NP_080688",
        "name": "small kinetochore-associated protein",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_080688"
    },
    "gene_names": [
        {
            "name": "Knstrn",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/Q9D9Z1",
            "id": "Q9D9Z1"
        },
        {
            "name": "1700025D04Rik; C15orf23; D2Ertd750e; SKAP; Traf4af1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_080688",
            "id": "NP_080688"
        },
        {
            "name": "D2Ertd750e",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/Q9D9Z1",
            "id": "Q9D9Z1"
        },
        {
            "name": "Knstrn",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_080688",
            "id": "NP_080688"
        },
        {
            "name": "Skap",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/Q9D9Z1",
            "id": "Q9D9Z1"
        },
        {
            "name": "Traf4af1",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/Q9D9Z1",
            "id": "Q9D9Z1"
        }
    ],
    "protein_names": [
        {
            "name": "Small kinetochore-associated protein",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "Q9D9Z1"
        },
        {
            "name": "Kinastrin",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q9D9Z1"
        },
        {
            "name": "Kinetochore-localized astrin-binding protein",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q9D9Z1"
        },
        {
            "name": "Kinetochore-localized astrin/SPAG5-binding protein",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q9D9Z1"
        },
        {
            "name": "SKAP",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q9D9Z1"
        },
        {
            "name": "TRAF4 associated factor 1 homolog; putative TRAF4-associated factor 1; kinetochore-localized astrin/SPAG5-binding protein; kinastrin; kinetochore-localized astrin-binding protein",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_080688",
            "id": "NP_080688"
        },
        {
            "name": "TRAF4-associated factor 1",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q9D9Z1"
        },
        {
            "name": "small kinetochore-associated protein",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_080688",
            "id": "NP_080688"
        }
    ],
    "function": [
        {
            "annotation": "Essential component of the mitotic spindle required for faithful chromosome segregation and progression into anaphase. Promotes the metaphase-to-anaphase transition and is required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. The astrin (SPAG5)-kinastrin (SKAP) complex promotes stable microtubule-kinetochore attachments. Required for kinetochore oscillations and dynamics of microtubule plus-ends during live cell mitosis, possibly by forming a link between spindle microtubule plus-ends and mitotic chromosomes to achieve faithful cell division.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q9D9Z1",
                    "url": "https://www.uniprot.org/uniprot/Q9D9Z1#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "Q9Y448",
                    "url": "https://www.uniprot.org/uniprot/Q9Y448#function"
                }
            ]
        },
        {
            "annotation": "Important role in the successful outcome of male gametogenesis",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_080688",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_080688"
                },
                {
                    "database": "PubMed",
                    "id": "26667018",
                    "url": "https://glygen.org/publication/PubMed/26667018"
                }
            ]
        }
    ],
    "disease": [
        {
            "disease_id": "DOID:3151",
            "recommended_name": {
                "id": "DOID:3151",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:3151",
                "name": "skin squamous cell carcinoma",
                "description": "A skin carcinoma that has_material_basis_in squamous cells."
            },
            "synonyms": [
                {
                    "id": "DOID:3151",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:3151",
                    "name": "Epidermoid skin carcinoma",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "3151",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:3151"
                }
            ]
        },
        {
            "disease_id": "DOID:8866",
            "recommended_name": {
                "id": "DOID:8866",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:8866",
                "name": "actinic keratosis",
                "description": ""
            },
            "synonyms": [
                {
                    "id": "DOID:8866",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:8866",
                    "name": "SK - Solar keratosis",
                    "description": ""
                },
                {
                    "id": "DOID:8866",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:8866",
                    "name": "Senile hyperkeratosis",
                    "description": ""
                },
                {
                    "id": "DOID:8866",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:8866",
                    "name": "Solar keratosis",
                    "description": ""
                },
                {
                    "id": "DOID:8866",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:8866",
                    "name": "actinic (Solar) Keratosis",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "8866",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:8866"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q9D9Z1",
                    "url": "https://www.uniprot.org/uniprot/Q9D9Z1"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "gene": [
        {
            "name": "Knstrn",
            "url": "https://www.uniprot.org/uniprot/Q9D9Z1",
            "locus": {
                "chromosome": "2",
                "start_pos": 118684438,
                "end_pos": 118644484,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSMUSG00000027331",
                        "url": "https://www.ensembl.org/id/ENSMUSG00000027331"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSMUSG00000027331",
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000027331",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "51944",
            "url": "https://www.ncbi.nlm.nih.gov/gene/51944",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "Q9D9Z1",
            "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9D9Z1*",
            "database": "IntAct",
            "categories": [
                "Other"
            ]
        },
        {
            "id": "IPR033373",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR033373",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "mmu:51944",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:51944",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "1289298",
            "url": "http://www.informatics.jax.org/marker/MGI:1289298",
            "database": "MGI",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "Q9D9Z1",
            "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9D9Z1",
            "database": "O-GlcNAc Database",
            "categories": [
                "Glycoproteomics"
            ]
        },
        {
            "id": "QDSCLAI",
            "url": "https://omabrowser.org/oma/group/QDSCLAI/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "4607711at2759",
            "url": "http://www.orthodb.org/?query=4607711at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR31940",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31940",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR31940:SF2",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31940:SF2",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_Q9D9Z1",
            "url": "http://purl.obolibrary.org/obo/PR_Q9D9Z1",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "NP_080688",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_080688",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A3KGG6",
            "url": "https://www.uniprot.org/uniprot/A3KGG6",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A3KGG6-1",
            "url": "https://www.uniprot.org/uniprot/A3KGG6-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A3KGG8",
            "url": "https://www.uniprot.org/uniprot/A3KGG8",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A3KGG8-1",
            "url": "https://www.uniprot.org/uniprot/A3KGG8-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "F6UVD3",
            "url": "https://www.uniprot.org/uniprot/F6UVD3",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "F6UVD3-1",
            "url": "https://www.uniprot.org/uniprot/F6UVD3-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "F7BE71",
            "url": "https://www.uniprot.org/uniprot/F7BE71",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "F7BE71-1",
            "url": "https://www.uniprot.org/uniprot/F7BE71-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "H3BJ95",
            "url": "https://www.uniprot.org/uniprot/H3BJ95",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "H3BJ95-1",
            "url": "https://www.uniprot.org/uniprot/H3BJ95-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "H3BJJ3",
            "url": "https://www.uniprot.org/uniprot/H3BJJ3",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "H3BJJ3-1",
            "url": "https://www.uniprot.org/uniprot/H3BJJ3-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "H3BKK2",
            "url": "https://www.uniprot.org/uniprot/H3BKK2",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "H3BKK2-1",
            "url": "https://www.uniprot.org/uniprot/H3BKK2-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "H3BKV9",
            "url": "https://www.uniprot.org/uniprot/H3BKV9",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "H3BKV9-1",
            "url": "https://www.uniprot.org/uniprot/H3BKV9-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q9D9Z1",
            "url": "https://www.uniprot.org/uniprot/Q9D9Z1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q9D9Z1-1",
            "url": "https://www.uniprot.org/uniprot/Q9D9Z1-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MAAPEAEAQETAFRTTGPPTDSEPRPFPPSSRKFPFESAAADSNEDWAVAAEHYLKGSGENGGWEQPAPGVQPSHPATMASAKTVCDAQPHSMPSCGLPADTQTRATSKLPVKSKEADLLRHLHPGGPEPDVTKVTKSRRENGQVKAAETASRRNLRNSYKPFNKQKPEEELKDKNELLEAVNKQLHQKLTETQGELKDLTQKVELLEKFQDNCLALLESKGLNPGQETLASKQEPTTDHTDSMLLLETLKDELKVFNETAKKQMEELQALKVKLKLKEEESVQFLEQQTLCKDEASDFTIILEEMEQLLEM",
        "length": 312,
        "header": "sp|Q9D9Z1-1|SKAP_MOUSE Isoform 1 of Small kinetochore-associated protein  OS=Mus musculus OX=10090 GN=Knstrn PE=2 SV=2 CANONICAL=Q9D9Z1-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A3KGG6-1",
            "url": "",
            "sequence": {
                "sequence": "EHYLKGSGENGGWEQPAPGVQPSHPATMASAKTVCDAQPHSMPSCGLPADTQTRATSKLPVKSKEADLLRHLHPGGPEPDVTKVTKSRRENGQVKAAETASRRNLRNSYKPFNKQKPEEELKDKNELLEAVNKQLHQKLTETQGELKDLTQKVELLEKFQDNCLALLESKGLNPAAARNFERRTEGFQ",
                "length": 188,
                "header": "tr|A3KGG6-1|SKAP_MOUSE Computationally mapped isoform of Small kinetochore-associated protein  OS=Mus musculus OX=10090 GN=Knstrn PE=2 SV=1 CANONICAL=Q9D9Z1-1"
            },
            "locus": {
                "chromosome": "2",
                "start_pos": 118662074,
                "end_pos": 118644735,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000028803.14",
                        "url": "https://www.ensembl.org/id/ENSMUST00000028803.14"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000028803.8",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000028803.8"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A3KGG8-1",
            "url": "",
            "sequence": {
                "sequence": "MASAKTVCDAQPHSMPSCGLPADTQTRATSKLPVKSKEADLLRHLHPGGPEPDVTKVTKSRRENGQVKAAETASRRNLRNSYKPFNKQKPEEELKDKNELLEAVNKQLHQKLTETQGELKDLTQKVELLEKFQDNCLALLESKGLNPGQETLASKQEPTTDHTDSMLLLETLKDELKVFNETAKKQMEELQALKVKLKLKEEESVQFLEQQTLCKDEASDFTIILEEMEQLLEM",
                "length": 234,
                "header": "tr|A3KGG8-1|SKAP_MOUSE Computationally mapped isoform of Small kinetochore-associated protein  OS=Mus musculus OX=10090 GN=Knstrn PE=2 SV=1 CANONICAL=Q9D9Z1-1"
            },
            "locus": {
                "chromosome": "2",
                "start_pos": 118664609,
                "end_pos": 118644907,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000110842.8",
                        "url": "https://www.ensembl.org/id/ENSMUST00000110842.8"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000106466.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000106466.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "F6UVD3-1",
            "url": "",
            "sequence": {
                "sequence": "XEDWAVAAEHYLKGSGENGGWEQPAPGVQPSHPATMASAKTVCDAQPHSMPSCGLPAGR",
                "length": 59,
                "header": "tr|F6UVD3-1|SKAP_MOUSE Computationally mapped isoform of Small kinetochore-associated protein  OS=Mus musculus OX=10090 GN=Knstrn PE=2 SV=1 CANONICAL=Q9D9Z1-1"
            },
            "locus": {
                "chromosome": "2",
                "start_pos": 118649322,
                "end_pos": 118644713,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000134579.8",
                        "url": "https://www.ensembl.org/id/ENSMUST00000134579.8"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000123065.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000123065.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "F7BE71-1",
            "url": "",
            "sequence": {
                "sequence": "XENGGWEQPAPGVQPSHPATMASAKTVCDAQPHSMPSCGLPADTQTRATSKLPVKSKEADLLRHLHPGGPEPDVTKVTKSRRENGQVKAAETASRRNLRNSYKPFNKQKPEEELKDKNELLEAVNKQLHQKLTETQGELKDLTQKVELLEKFQDNCLALLESKGLNPGQETLASKQEPTTDHTDSMIGYHGASQESHFWLASEFAVTWLLRSVQYRAH",
                "length": 218,
                "header": "tr|F7BE71-1|F7BE71_MOUSE Computationally mapped isoform of Kinetochore-localized astrin/SPAG5 binding  OS=Mus musculus OX=10090 GN=Knstrn PE=1 SV=1 CANONICAL=Q9D9Z1-1"
            },
            "locus": {
                "chromosome": "2",
                "start_pos": 118661450,
                "end_pos": 118644758,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000126045.8",
                        "url": "https://www.ensembl.org/id/ENSMUST00000126045.8"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000122844.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000122844.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "H3BJ95-1",
            "url": "",
            "sequence": {
                "sequence": "XEDWAVAAEHYLKGSGENGGWEQPAPGVQPSHPATMASAKTVCDAQPHSMPSCGLPAATNRLISKNRRRN",
                "length": 70,
                "header": "tr|H3BJ95-1|SKAP_MOUSE Computationally mapped isoform of Small kinetochore-associated protein  OS=Mus musculus OX=10090 GN=Knstrn PE=2 SV=1 CANONICAL=Q9D9Z1-1"
            },
            "locus": {
                "chromosome": "2",
                "start_pos": 118653940,
                "end_pos": 118644713,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000177103.8",
                        "url": "https://www.ensembl.org/id/ENSMUST00000177103.8"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000134898.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000134898.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "H3BJJ3-1",
            "url": "",
            "sequence": {
                "sequence": "EASDFTIILEEMEQLLEM",
                "length": 18,
                "header": "tr|H3BJJ3-1|SKAP_MOUSE Computationally mapped isoform of Small kinetochore-associated protein  OS=Mus musculus OX=10090 GN=Knstrn PE=2 SV=1 CANONICAL=Q9D9Z1-1"
            },
            "locus": {
                "chromosome": "2",
                "start_pos": 118664609,
                "end_pos": 118664556,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000148877.2",
                        "url": "https://www.ensembl.org/id/ENSMUST00000148877.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000135008.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000135008.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "H3BKK2-1",
            "url": "",
            "sequence": {
                "sequence": "QPAPGVQPSHPATMASAKTVCDAQPHSMPSCGLPADTQTRATSKLPVKSKEADLLRHLHPGGPEPDVTKVTKSRRENGQVKAAETASRRNLRNSYKPFNKQKPEEELKDKNELLEAVNKQLHQKLTETQGELKDLTQKVELLEKFQDNCLALLESKGLNPGQETLASKQEPTTDHTDSMKDRLFEA",
                "length": 186,
                "header": "tr|H3BKK2-1|SKAP_MOUSE Computationally mapped isoform of Small kinetochore-associated protein  OS=Mus musculus OX=10090 GN=Knstrn PE=2 SV=1 CANONICAL=Q9D9Z1-1"
            },
            "locus": {
                "chromosome": "2",
                "start_pos": 118661313,
                "end_pos": 118644777,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000123104.2",
                        "url": "https://www.ensembl.org/id/ENSMUST00000123104.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000135422.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000135422.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "H3BKV9-1",
            "url": "",
            "sequence": {
                "sequence": "KVFNETAKKQMEELQALKVKLKLKEEESVQFLEQQTLCKDEASDFTIILEEMEQLLEM",
                "length": 58,
                "header": "tr|H3BKV9-1|SKAP_MOUSE Computationally mapped isoform of Small kinetochore-associated protein  OS=Mus musculus OX=10090 GN=Knstrn PE=2 SV=1 CANONICAL=Q9D9Z1-1"
            },
            "locus": {
                "chromosome": "2",
                "start_pos": 118664609,
                "end_pos": 118662064,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000176463.2",
                        "url": "https://www.ensembl.org/id/ENSMUST00000176463.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000135549.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000135549.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q9D9Z1-1",
            "url": "",
            "sequence": {
                "sequence": "MAAPEAEAQETAFRTTGPPTDSEPRPFPPSSRKFPFESAAADSNEDWAVAAEHYLKGSGENGGWEQPAPGVQPSHPATMASAKTVCDAQPHSMPSCGLPADTQTRATSKLPVKSKEADLLRHLHPGGPEPDVTKVTKSRRENGQVKAAETASRRNLRNSYKPFNKQKPEEELKDKNELLEAVNKQLHQKLTETQGELKDLTQKVELLEKFQDNCLALLESKGLNPGQETLASKQEPTTDHTDSMLLLETLKDELKVFNETAKKQMEELQALKVKLKLKEEESVQFLEQQTLCKDEASDFTIILEEMEQLLEM",
                "length": 312,
                "header": "sp|Q9D9Z1-1|SKAP_MOUSE Isoform 1 of Small kinetochore-associated protein  OS=Mus musculus OX=10090 GN=Knstrn PE=2 SV=2 CANONICAL=Q9D9Z1-1"
            },
            "locus": {
                "chromosome": "2",
                "start_pos": 118664609,
                "end_pos": 118644582,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000134661",
                        "url": "https://www.ensembl.org/id/ENSMUST00000134661"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000115860",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000115860"
                    }
                ]
            }
        }
    ],
    "glycosylation": [
        {
            "glytoucan_ac": "G49108TO",
            "type": "O-linked",
            "subtype": "O-GlcNAcylation",
            "site_category": "reported_with_glycan",
            "site_seq": "",
            "relation": "attached",
            "comment": "O-GlcNAcylation",
            "evidence": [
                {
                    "id": "Q9D9Z1",
                    "database": "O-GlcNAc Database",
                    "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9D9Z1"
                },
                {
                    "id": "28528544",
                    "database": "PubMed",
                    "url": "https://glygen.org/publication/PubMed/28528544"
                },
                {
                    "id": "25153642",
                    "database": "PubMed",
                    "url": "https://glygen.org/publication/PubMed/25153642"
                }
            ]
        }
    ],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [
        "glycoprotein",
        "glycoprotein_reported_with_glycan"
    ],
    "publication": [
        {
            "title": "Changes in metabolic chemical reporter structure yield a selective probe of O-GlcNAc modification.",
            "journal": "Journal of the American Chemical Society",
            "date": "2014",
            "authors": "Chuh KN, Zaro BW, Piller F, Piller V, Pratt MR",
            "evidence": [
                {
                    "database": "O-GlcNAc Database",
                    "id": "Q9D9Z1",
                    "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9D9Z1"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "25153642",
                    "url": "https://glygen.org/publication/PubMed/25153642"
                }
            ]
        },
        {
            "title": "SKAP, an outer kinetochore protein, is required for mouse germ cell development.",
            "journal": "Reproduction (Cambridge, England)",
            "date": "2016",
            "authors": "Grey C, Espeut J, Ametsitsi R, Kumar R, Luksza M, Brun C, Verlhac MH, Suja JA, de Massy B",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_080688",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_080688"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "26667018",
                    "url": "https://glygen.org/publication/PubMed/26667018"
                }
            ]
        },
        {
            "title": "The New Chemical Reporter 6-Alkynyl-6-deoxy-GlcNAc Reveals O-GlcNAc Modification of the Apoptotic Caspases That Can Block the Cleavage/Activation of Caspase-8.",
            "journal": "Journal of the American Chemical Society",
            "date": "2017",
            "authors": "Chuh KN, Batt AR, Zaro BW, Darabedian N, Marotta NP, Brennan CK, Amirhekmat A, Pratt MR",
            "evidence": [
                {
                    "database": "O-GlcNAc Database",
                    "id": "Q9D9Z1",
                    "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9D9Z1"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "28528544",
                    "url": "https://glygen.org/publication/PubMed/28528544"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "mmu:51944",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:51944",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q6AXN6-1",
            "protein_name": "Small kinetochore-associated protein",
            "gene_name": "Knstrn",
            "tax_id": 10116,
            "organism": "Rattus norvegicus",
            "sequence": {
                "sequence": "MATHKAEAQETDFRTTGPPTDLEQCPFPPSSRKFPFESVAADSTEGWAVAAEHHLKRSGEDGGWEQPASGVEPSRPTTMASSKTVCDAQPHSMPSCGLSADTQTRATSKLPVKSKDAEMLRHLHTGGLEPDVTKVTKPRRENGQGKAAETASRRNIRSSYKPLSKQKPEEDLKDKNELLEAVNKQLHQKLTETQGELKDLTQKVELLEKFQDNCLAILESKGLNSGQETQESKQEPSTDPTDSMLLLETLKDELKLFNETAKKQMEELQALKVKLKLKEKERIQFLEQQTLGKDEASDFTIILEEMEQLLEM",
                "length": 312
            },
            "evidence": [
                {
                    "id": "45238316",
                    "url": "http://www.informatics.jax.org/homology/45238316",
                    "database": "MGI"
                }
            ],
            "common_name": "Rat"
        },
        {
            "uniprot_canonical_ac": "Q9Y448-1",
            "protein_name": "Small kinetochore-associated protein",
            "gene_name": "KNSTRN",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MAAPEAPPLDRVFRTTWLSTECDSHPLPPSYRKFLFETQAADLAGGTTVAAGNLLNESEKDCGQDRRAPGVQPCRLVTMTSVVKTVYSLQPPSALSGGQPADTQTRATSKSLLPVRSKEVDVSKQLHSGGPENDVTKITKLRRENGQMKATDTATRRNVRKGYKPLSKQKSEEELKDKNQLLEAVNKQLHQKLTETQGELKDLTQKVELLEKFRDNCLAILESKGLDPALGSETLASRQESTTDHMDSMLLLETLQEELKLFNETAKKQMEELQALKVKLEMKEERVRFLEQQTLCNNQVNDLTTALKEMEQLLEM",
                "length": 316
            },
            "evidence": [
                {
                    "id": "45238316",
                    "url": "http://www.informatics.jax.org/homology/45238316",
                    "database": "MGI"
                },
                {
                    "id": "Q9D9Z1",
                    "url": "https://omabrowser.org/oma/group/Q9D9Z1/",
                    "database": "OMA"
                }
            ],
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Biological Process",
                "total": 8,
                "go_terms": [
                    {
                        "name": "chromosome segregation",
                        "id": "GO:0007059",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007059",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q9D9Z1",
                                "url": "https://www.uniprot.org/uniprot/Q9D9Z1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "regulation of attachment of spindle microtubules to kinetochore",
                        "id": "GO:0051988",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051988",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q9D9Z1",
                                "url": "https://www.uniprot.org/uniprot/Q9D9Z1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "spindle organization",
                        "id": "GO:0007051",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007051",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q9D9Z1",
                                "url": "https://www.uniprot.org/uniprot/Q9D9Z1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cell migration",
                        "id": "GO:0016477",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q9D9Z1",
                                "url": "https://www.uniprot.org/uniprot/Q9D9Z1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cell division",
                        "id": "GO:0051301",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q9D9Z1",
                                "url": "https://www.uniprot.org/uniprot/Q9D9Z1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "microtubule cytoskeleton organization",
                        "id": "GO:0000226",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q9D9Z1",
                                "url": "https://www.uniprot.org/uniprot/Q9D9Z1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cellular response to epidermal growth factor stimulus",
                        "id": "GO:0071364",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071364",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q9D9Z1",
                                "url": "https://www.uniprot.org/uniprot/Q9D9Z1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "mitotic sister chromatid segregation",
                        "id": "GO:0000070",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000070",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q9D9Z1",
                                "url": "https://www.uniprot.org/uniprot/Q9D9Z1"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 10,
                "go_terms": [
                    {
                        "name": "kinetochore",
                        "id": "GO:0000776",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000776",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q9D9Z1",
                                "url": "https://www.uniprot.org/uniprot/Q9D9Z1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "spindle pole",
                        "id": "GO:0000922",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q9D9Z1",
                                "url": "https://www.uniprot.org/uniprot/Q9D9Z1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "nucleus",
                        "id": "GO:0005634",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q9D9Z1",
                                "url": "https://www.uniprot.org/uniprot/Q9D9Z1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cytoplasm",
                        "id": "GO:0005737",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q9D9Z1",
                                "url": "https://www.uniprot.org/uniprot/Q9D9Z1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "plasma membrane",
                        "id": "GO:0005886",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q9D9Z1",
                                "url": "https://www.uniprot.org/uniprot/Q9D9Z1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "microtubule organizing center",
                        "id": "GO:0005815",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005815",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q9D9Z1",
                                "url": "https://www.uniprot.org/uniprot/Q9D9Z1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "ruffle",
                        "id": "GO:0001726",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001726",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q9D9Z1",
                                "url": "https://www.uniprot.org/uniprot/Q9D9Z1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "centriolar satellite",
                        "id": "GO:0034451",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034451",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q9D9Z1",
                                "url": "https://www.uniprot.org/uniprot/Q9D9Z1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "microtubule plus-end",
                        "id": "GO:0035371",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035371",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q9D9Z1",
                                "url": "https://www.uniprot.org/uniprot/Q9D9Z1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "mitotic spindle",
                        "id": "GO:0072686",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q9D9Z1",
                                "url": "https://www.uniprot.org/uniprot/Q9D9Z1"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 2,
                "go_terms": [
                    {
                        "name": "protein homodimerization activity",
                        "id": "GO:0042803",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q9D9Z1",
                                "url": "https://www.uniprot.org/uniprot/Q9D9Z1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "microtubule plus-end binding",
                        "id": "GO:0051010",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051010",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q9D9Z1",
                                "url": "https://www.uniprot.org/uniprot/Q9D9Z1"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 258,
            "end_pos": 260,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        },
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        },
        {
            "name": "homologset.oma",
            "label": "OMA Homologs"
        }
    ],
    "section_stats": [
        {
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            "table_stats": [
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                    "field": "total",
                    "count": 1
                },
                {
                    "field": "total_sites",
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                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
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                },
                {
                    "field": "o_linked_glycans",
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                {
                    "field": "o_linked_glycan_sites",
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                }
            ],
            "sort_fields": [
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                "subtype",
                "site_category",
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        },
        {
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                {
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                {
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                {
                    "field": "n_linked_glycan_sites",
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                },
                {
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                },
                {
                    "field": "o_linked_glycan_sites",
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                }
            ],
            "sort_fields": []
        },
        {
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                {
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                {
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                {
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                {
                    "field": "o_linked_glycans",
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            "sort_fields": [
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        },
        {
            "table_id": "glycosylation_predicted",
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                },
                {
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                {
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                {
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                {
                    "field": "o_linked_glycan_sites",
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            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_automatic_literature_mining",
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                {
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                {
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                {
                    "field": "o_linked_glycan_sites",
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            ],
            "sort_fields": []
        },
        {
            "table_id": "phosphorylation",
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                    "field": "total",
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                },
                {
                    "field": "total_sites",
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            ],
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        {
            "table_id": "snv",
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        {
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        {
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