{
    "uniprot_canonical_ac": "Q9D8U2-1",
    "uniprot_ac": "Q9D8U2",
    "uniprot_id": "TM41A_MOUSE",
    "mass": {
        "chemical_mass": 29370.0,
        "monoisotopic_mass": 29370.0
    },
    "refseq": {
        "ac": "NP_079969",
        "name": "transmembrane protein 41A precursor",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_079969"
    },
    "gene_names": [
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            "name": "Tmem41a",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/Q9D8U2",
            "id": "Q9D8U2"
        },
        {
            "name": "2900010K02Rik; 5730578N08Rik",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_079969",
            "id": "NP_079969"
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            "name": "Tmem41a",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_079969",
            "id": "NP_079969"
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        {
            "name": "Transmembrane protein 41A",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "Q9D8U2"
        },
        {
            "name": "transmembrane protein 41A precursor",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_079969",
            "id": "NP_079969"
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    ],
    "function": [
        {
            "annotation": "The present study demonstrated a reduction in TMEM41A expression levels in a pair of GC cell lines, and revealed that high TMEM41A expression levels may promote GC-associated metastasis, which may be mediated by the downregulation of E-cadherin expression.",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_079969",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_079969"
                },
                {
                    "database": "PubMed",
                    "id": "30015937",
                    "url": "https://glygen.org/publication/PubMed/30015937"
                }
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    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
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                    "url": "https://www.uniprot.org/uniprot/Q9D8U2"
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            ],
            "common_name": "Mouse"
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            "url": "https://www.uniprot.org/uniprot/Q9D8U2",
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                        "id": "ENSMUSG00000022856",
                        "url": "https://www.ensembl.org/id/ENSMUSG00000022856"
                    }
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            }
        }
    ],
    "crossref": [
        {
            "id": "ENSMUSG00000022856",
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000022856",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "66664",
            "url": "https://www.ncbi.nlm.nih.gov/gene/66664",
            "database": "GeneID",
            "categories": [
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        },
        {
            "id": "IPR032816",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR032816",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR045014",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR045014",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "mmu:66664",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:66664",
            "database": "KEGG Pathway",
            "categories": [
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        {
            "id": "1913914",
            "url": "http://www.informatics.jax.org/marker/MGI:1913914",
            "database": "MGI",
            "categories": [
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            ]
        },
        {
            "id": "WWMTGTG",
            "url": "https://omabrowser.org/oma/group/WWMTGTG/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
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        },
        {
            "id": "178922at2759",
            "url": "http://www.orthodb.org/?query=178922at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR43220:SF21",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43220:SF21",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF09335",
            "url": "http://pfam.xfam.org/family/PF09335",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_Q9D8U2",
            "url": "http://purl.obolibrary.org/obo/PR_Q9D8U2",
            "database": "PRO",
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            "id": "A0A338P6N6",
            "url": "https://www.uniprot.org/uniprot/A0A338P6N6",
            "database": "UniProtKB",
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        },
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            "url": "https://www.uniprot.org/uniprot/Q9D8U2",
            "database": "UniProtKB",
            "categories": [
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        },
        {
            "id": "Q9D8U2-1",
            "url": "https://www.uniprot.org/uniprot/Q9D8U2-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
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        "sequence": "MRALLGLLLVFGGCTFALYLLSTRLPLGPRLAAAGEPEGRSLWFPSDLAELRELSEVLREYRKEHQAYVFLLFCSAYLYKQGFAIPGSSFLNVLAGALFGPWLGLLLCCVLTSVGATGCYLLSSLFGKQLVISYFPDKVALLQKKVEENRNSLFFFLLFLRLFPMTPNWFLNLSAPILNIPIVQFFFSVLIGLIPYNFICVQTGSILSTLTSLDALFSWETVLKLLAIALVALVPGTLIKKFSQKRLALSETSDIGHPDRRKDA",
        "length": 264,
        "header": "sp|Q9D8U2-1|TM41A_MOUSE Isoform 1 of Transmembrane protein 41A  OS=Mus musculus OX=10090 GN=Tmem41a PE=2 SV=1 CANONICAL=Q9D8U2-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A338P6N6-1",
            "url": "",
            "sequence": {
                "sequence": "MRALLGLLLVFGGCTFALYLLSTRLPLGPRLAAAGEPEGRMFWLVPCSGHGWDFCCAAC",
                "length": 59,
                "header": "tr|A0A338P6N6-1|TM41A_MOUSE Computationally mapped isoform of Transmembrane protein 41A  OS=Mus musculus OX=10090 GN=Tmem41a PE=2 SV=1 CANONICAL=Q9D8U2-1"
            },
            "locus": {
                "chromosome": "16",
                "start_pos": 21766236,
                "end_pos": 21756787,
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                "evidence": [
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                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000232635.2",
                        "url": "https://www.ensembl.org/id/ENSMUST00000232635.2"
                    },
                    {
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                        "id": "ENSMUSP00000156055.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000156055.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q9D8U2-1",
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                "sequence": "MRALLGLLLVFGGCTFALYLLSTRLPLGPRLAAAGEPEGRSLWFPSDLAELRELSEVLREYRKEHQAYVFLLFCSAYLYKQGFAIPGSSFLNVLAGALFGPWLGLLLCCVLTSVGATGCYLLSSLFGKQLVISYFPDKVALLQKKVEENRNSLFFFLLFLRLFPMTPNWFLNLSAPILNIPIVQFFFSVLIGLIPYNFICVQTGSILSTLTSLDALFSWETVLKLLAIALVALVPGTLIKKFSQKRLALSETSDIGHPDRRKDA",
                "length": 264,
                "header": "sp|Q9D8U2-1|TM41A_MOUSE Isoform 1 of Transmembrane protein 41A  OS=Mus musculus OX=10090 GN=Tmem41a PE=2 SV=1 CANONICAL=Q9D8U2-1"
            },
            "locus": {
                "chromosome": "16",
                "start_pos": 21766236,
                "end_pos": 21753578,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000023562",
                        "url": "https://www.ensembl.org/id/ENSMUST00000023562"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000023562",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000023562"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [
        {
            "title": "Expression of transmembrane protein 41A is associated with metastasis via the modulation of Ecadherin in radically resected gastric cancer.",
            "journal": "Molecular medicine reports",
            "date": "2018",
            "authors": "Lin B, Xue Y, Qi C, Chen X, Mao W",
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                    "id": "NP_079969",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_079969"
                }
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    ],
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            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:66664",
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            "name": "homologset.mgi",
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