{
    "uniprot_canonical_ac": "Q9D746-1",
    "uniprot_ac": "Q9D746",
    "uniprot_id": "Q9D746_MOUSE",
    "mass": {
        "chemical_mass": 23237.0,
        "monoisotopic_mass": 23237.0
    },
    "refseq": {
        "ac": "NP_473441",
        "name": "uncharacterized protein LOC117172",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_473441"
    },
    "gene_names": [
        {
            "name": "2310034C09Rik",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/Q9D746",
            "id": "Q9D746"
        },
        {
            "name": "2310034C09Rik",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_473441",
            "id": "NP_473441"
        }
    ],
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        {
            "name": "Keratin-associated protein",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "Q9D746"
        },
        {
            "name": "uncharacterized protein LOC117172",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_473441",
            "id": "NP_473441"
        }
    ],
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        {
            "annotation": "In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.",
            "evidence": [
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                    "database": "UniProtKB",
                    "id": "Q9D746",
                    "url": "https://www.uniprot.org/uniprot/Q9D746#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "RU369044",
                    "url": "https://www.uniprot.org/uniprot/RU369044#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "ARBA00003327",
                    "url": "https://www.uniprot.org/uniprot/ARBA00003327#function"
                }
            ]
        },
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            "annotation": "Krtap16 is a hair keratin-associated protein gene complex regulated by Hoxc13; localized to chromosome 16",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_473441",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_473441"
                },
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                    "database": "PubMed",
                    "id": "15385554",
                    "url": "https://glygen.org/publication/PubMed/15385554"
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            ]
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    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
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                    "id": "Q9D746",
                    "url": "https://www.uniprot.org/uniprot/Q9D746"
                }
            ],
            "common_name": "Mouse"
        }
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            "name": "2310034C09Rik",
            "url": "https://www.uniprot.org/uniprot/Q9D746",
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                "start_pos": 88556680,
                "end_pos": 88555735,
                "strand": "-",
                "evidence": [
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                        "database": "Ensembl Gene",
                        "id": "ENSMUSG00000068078",
                        "url": "https://www.ensembl.org/id/ENSMUSG00000068078"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSMUSG00000068078",
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000068078",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "117172",
            "url": "https://www.ncbi.nlm.nih.gov/gene/117172",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR007659",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR007659",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR007951",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR007951",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "mmu:117172",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:117172",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "2152338",
            "url": "http://www.informatics.jax.org/marker/MGI:2152338",
            "database": "MGI",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "CWEPASC",
            "url": "https://omabrowser.org/oma/group/CWEPASC/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "5264457at2759",
            "url": "http://www.orthodb.org/?query=5264457at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR23260",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23260",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR23260:SF7",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23260:SF7",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF05287",
            "url": "http://pfam.xfam.org/family/PF05287",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-MMU-6805567",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-6805567",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "NP_473441",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_473441",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q9D746",
            "url": "https://www.uniprot.org/uniprot/Q9D746",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q9D746-1",
            "url": "https://www.uniprot.org/uniprot/Q9D746-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MAYSCCSGNFSSRSLRSCLPSSGSCRGSSYPSNLVYTTTSCSPSTCQLSSTLNPGFQETCIEPIRCQETCIEPIRCQETCTEPIRCQESCIEPIRCQETCIEPISCQRSCVVPSSCQKPCYYPRSSTPYRPCQGTYAGSLGFGSRSCSSLAYGSRSCYSVGYGNSGFRPLNCGVYGFPSLSYGSRYCSPIYFASRSCQPCYRPTWGSGLCGISC",
        "length": 214,
        "header": "tr|Q9D746-1|Q9D746_MOUSE Isoform 1 of Keratin-associated protein  OS=Mus musculus OX=10090 GN=2310034C09Rik PE=1 SV=1 CANONICAL=Q9D746-1"
    },
    "isoforms": [
        {
            "isoform_ac": "Q9D746-1",
            "url": "",
            "sequence": {
                "sequence": "MAYSCCSGNFSSRSLRSCLPSSGSCRGSSYPSNLVYTTTSCSPSTCQLSSTLNPGFQETCIEPIRCQETCIEPIRCQETCTEPIRCQESCIEPIRCQETCIEPISCQRSCVVPSSCQKPCYYPRSSTPYRPCQGTYAGSLGFGSRSCSSLAYGSRSCYSVGYGNSGFRPLNCGVYGFPSLSYGSRYCSPIYFASRSCQPCYRPTWGSGLCGISC",
                "length": 214,
                "header": "tr|Q9D746-1|Q9D746_MOUSE Isoform 1 of Keratin-associated protein  OS=Mus musculus OX=10090 GN=2310034C09Rik PE=1 SV=1 CANONICAL=Q9D746-1"
            },
            "locus": {
                "chromosome": "16",
                "start_pos": 88556429,
                "end_pos": 88555788,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000089111.5",
                        "url": "https://www.ensembl.org/id/ENSMUST00000089111.5"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000140130.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000140130.2"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [
        {
            "title": "Krtap16, characterization of a new hair keratin-associated protein (KAP) gene complex on mouse chromosome 16 and evidence for regulation by Hoxc13.",
            "journal": "The Journal of biological chemistry",
            "date": "2004",
            "authors": "Pruett ND, Tkatchenko TV, Jave-Suarez L, Jacobs DF, Potter CS, Tkatchenko AV, Schweizer J, Awgulewitsch A",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_473441",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_473441"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "15385554",
                    "url": "https://glygen.org/publication/PubMed/15385554"
                }
            ]
        },
        {
            "title": "Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.",
            "journal": "Mol. Cell. Proteomics",
            "date": "2014",
            "authors": "Guo A, Gu H, Zhou J, Mulhern D, Wang Y, Lee KA, Yang V, Aguiar M, Kornhauser J, Jia X, Ren J, Beausoleil SA, Silva JC, Vemulapalli V, Bedford MT, Comb MJ",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q9D746",
                    "url": "https://www.uniprot.org/uniprot/Q9D746"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "24129315",
                    "url": "https://glygen.org/publication/PubMed/24129315"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "mmu:117172",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:117172",
            "resource": "KEGG Pathway"
        },
        {
            "id": "R-MMU-6805567",
            "name": "Keratinization",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-6805567",
            "resource": "Reactome",
            "description": "Keratinization"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "A0A8I6A9J8-1",
            "protein_name": "Keratin-associated protein",
            "gene_name": "Krtap13-2",
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            "sequence": {
                "sequence": "MAYSCCSGNFSSRSLRSCLPSSGSCLASSYPSNLVYTTTSCSPSTCQLGSSLNSGCQETCIEPTSCQRSCVVSSPCQKPCYYPRSYTPCSPCQGTYAGSLSFGSRSCSSLGYGSRICYPVGCRSSGFGSMNCGVYGFPSLSYGSRCYYPTYLASSSCQPCYRPICGLGLYGTNC",
                "length": 174
            },
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                    "id": "45241798",
                    "url": "http://www.informatics.jax.org/homology/45241798",
                    "database": "MGI"
                }
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        },
        {
            "uniprot_canonical_ac": "D4AD54-1",
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            "gene_name": "LOC100363287",
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            "organism": "Rattus norvegicus",
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        {
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            "common_name": "Human"
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