{
    "uniprot_canonical_ac": "Q9CYZ8-1",
    "uniprot_ac": "Q9CYZ8",
    "uniprot_id": "SSBP2_MOUSE",
    "mass": {
        "chemical_mass": 37846.0,
        "monoisotopic_mass": 37846.0
    },
    "refseq": {
        "ac": "NP_077148",
        "name": "single-stranded DNA-binding protein 2 isoform 1",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_077148"
    },
    "gene_names": [
        {
            "name": "Ssbp2",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/Q9CYZ8",
            "id": "Q9CYZ8"
        },
        {
            "name": "1500004K09Rik; 2310079I02Rik; 9330163K02Rik; A830008M03Rik; Hspc116; SSDP2",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_077148",
            "id": "NP_077148"
        },
        {
            "name": "Ssbp2",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_077148",
            "id": "NP_077148"
        },
        {
            "name": "Ssdp2",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/Q9CYZ8",
            "id": "Q9CYZ8"
        }
    ],
    "protein_names": [
        {
            "name": "Single-stranded DNA-binding protein 2",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "Q9CYZ8"
        },
        {
            "name": "Sequence-specific single-stranded-DNA-binding protein 2",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q9CYZ8"
        },
        {
            "name": "sequence-specific single-stranded-DNA-binding protein 2",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_077148",
            "id": "NP_077148"
        },
        {
            "name": "single-stranded DNA-binding protein 2 isoform 1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_077148",
            "id": "NP_077148"
        }
    ],
    "function": [
        {
            "annotation": "GWAS in Mice Maps Susceptibility to HIV-Associated Nephropathy to the Ssbp2 Locus.",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_077148",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_077148"
                },
                {
                    "database": "PubMed",
                    "id": "34893534",
                    "url": "https://glygen.org/publication/PubMed/34893534"
                }
            ]
        },
        {
            "annotation": "The results uncovered a critical regulatory function for SSBP2 in hematopoietic stem and progenitor cells gene expression and function.",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_077148",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_077148"
                },
                {
                    "database": "PubMed",
                    "id": "25238756",
                    "url": "https://glygen.org/publication/PubMed/25238756"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [
        {
            "evidence": [
                {
                    "id": "rs3389302615",
                    "database": "dbSNP",
                    "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3389302615"
                }
            ],
            "glycoeffect": [
                "o-glyco-site-loss"
            ],
            "start_pos": 356,
            "end_pos": 356,
            "sequence_org": "S",
            "sequence_mut": "I",
            "comment": "Germline mutation passed 1 out of 1 filters: o-glyco-site-loss (S->I).",
            "chr_id": "13",
            "chr_pos": "91848795",
            "ref_nt": "T",
            "alt_nt": "null",
            "minor_allelic_frequency": "",
            "site_lbl": "S356",
            "keywords": [
                "ebi",
                "germline"
            ]
        }
    ],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q9CYZ8",
                    "url": "https://www.uniprot.org/uniprot/Q9CYZ8"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "gene": [
        {
            "name": "Ssbp2",
            "url": "https://www.uniprot.org/uniprot/Q9CYZ8",
            "locus": {
                "chromosome": "13",
                "start_pos": 91851548,
                "end_pos": 91608402,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSMUSG00000003992",
                        "url": "https://www.ensembl.org/id/ENSMUSG00000003992"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSMUSG00000003992",
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000003992",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "66970",
            "url": "https://www.ncbi.nlm.nih.gov/gene/66970",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "Q9CYZ8",
            "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9CYZ8*",
            "database": "IntAct",
            "categories": [
                "Other"
            ]
        },
        {
            "id": "IPR006594",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR006594",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR008116",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR008116",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "mmu:66970",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:66970",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "1914220",
            "url": "http://www.informatics.jax.org/marker/MGI:1914220",
            "database": "MGI",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "Q9CYZ8",
            "url": "https://oglcnac.org/atlas/detail/Q9CYZ8",
            "database": "O-GlcNAc Atlas",
            "categories": [
                "Glycoproteomics"
            ]
        },
        {
            "id": "GMPGMNX",
            "url": "https://omabrowser.org/oma/group/GMPGMNX/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "4371601at2759",
            "url": "http://www.orthodb.org/?query=4371601at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR12610",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12610",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR12610:SF23",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12610:SF23",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF04503",
            "url": "http://pfam.xfam.org/family/PF04503",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_Q9CYZ8",
            "url": "http://purl.obolibrary.org/obo/PR_Q9CYZ8",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "NP_077148",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_077148",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A338P6Q9",
            "url": "https://www.uniprot.org/uniprot/A0A338P6Q9",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A338P6Q9-1",
            "url": "https://www.uniprot.org/uniprot/A0A338P6Q9-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "D6RG78",
            "url": "https://www.uniprot.org/uniprot/D6RG78",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "D6RG78-1",
            "url": "https://www.uniprot.org/uniprot/D6RG78-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q9CYZ8",
            "url": "https://www.uniprot.org/uniprot/Q9CYZ8",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q9CYZ8-1",
            "url": "https://www.uniprot.org/uniprot/Q9CYZ8-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q9CYZ8-2",
            "url": "https://www.uniprot.org/uniprot/Q9CYZ8-2",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKAFHDYSAAAAPSPVLGNMPPGDGMPVGPVPPGFFQPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQNYGGAMRPPLNALGGPGMPGMNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPADSTNSGDNMYTLMNAVPPGPNRPNFPMGPGSDGPMGGLGGMESHHMNGSLGSGDMDSISKNSPNNMSLSNQPGTPRDDGEMGGNFLNPFQSESYSPSMTMSV",
        "length": 361,
        "header": "sp|Q9CYZ8-1|SSBP2_MOUSE Isoform 1 of Single-stranded DNA-binding protein 2  OS=Mus musculus OX=10090 GN=Ssbp2 PE=1 SV=1 CANONICAL=Q9CYZ8-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A338P6Q9-1",
            "url": "",
            "sequence": {
                "sequence": "MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKAFHDYSAAAAPSPVLGNMPPGDGMPVGPVPPGFFQPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQSDPWLSLQNYGGAMRPPLNALGGPGMPGMNMGPGGGRPWPNPTNANSIPYSSAS",
                "length": 244,
                "header": "tr|A0A338P6Q9-1|SSBP2_MOUSE Computationally mapped isoform of Single-stranded DNA-binding protein 2  OS=Mus musculus OX=10090 GN=Ssbp2 PE=1 SV=1 CANONICAL=Q9CYZ8-1"
            },
            "locus": {
                "chromosome": "13",
                "start_pos": 91831821,
                "end_pos": 91609306,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000231481.2",
                        "url": "https://www.ensembl.org/id/ENSMUST00000231481.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000156076.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000156076.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "D6RG78-1",
            "url": "",
            "sequence": {
                "sequence": "MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEGFSV",
                "length": 49,
                "header": "tr|D6RG78-1|SSBP2_MOUSE Computationally mapped isoform of Single-stranded DNA-binding protein 2  OS=Mus musculus OX=10090 GN=Ssbp2 PE=1 SV=1 CANONICAL=Q9CYZ8-1"
            },
            "locus": {
                "chromosome": "13",
                "start_pos": 91682107,
                "end_pos": 91609306,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000138488.2",
                        "url": "https://www.ensembl.org/id/ENSMUST00000138488.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000115548.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000115548.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q9CYZ8-1",
            "url": "",
            "sequence": {
                "sequence": "MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKAFHDYSAAAAPSPVLGNMPPGDGMPVGPVPPGFFQPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQNYGGAMRPPLNALGGPGMPGMNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPADSTNSGDNMYTLMNAVPPGPNRPNFPMGPGSDGPMGGLGGMESHHMNGSLGSGDMDSISKNSPNNMSLSNQPGTPRDDGEMGGNFLNPFQSESYSPSMTMSV",
                "length": 361,
                "header": "sp|Q9CYZ8-1|SSBP2_MOUSE Isoform 1 of Single-stranded DNA-binding protein 2  OS=Mus musculus OX=10090 GN=Ssbp2 PE=1 SV=1 CANONICAL=Q9CYZ8-1"
            },
            "locus": {
                "chromosome": "13",
                "start_pos": 91848811,
                "end_pos": 91609306,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000004094",
                        "url": "https://www.ensembl.org/id/ENSMUST00000004094"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000004094",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000004094"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q9CYZ8-2",
            "url": "",
            "sequence": {
                "sequence": "MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKAFHDYPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQNYGGAMRPPLNALGGPGMPGMNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPADSTNSGDNMYTLMNAVPPGPNRPNFPMGPGSDGPMGGLGGMESHHMNGSLGSGDMDSISKNSPNNMSLSNQPGTPRDDGEMGGNFLNPFQSESYSPSMTMSV",
                "length": 331,
                "header": "sp|Q9CYZ8-2|SSBP2_MOUSE Isoform 2 of Single-stranded DNA-binding protein 2  OS=Mus musculus OX=10090 GN=Ssbp2 PE=1 SV=1 CANONICAL=Q9CYZ8-1"
            },
            "locus": {
                "chromosome": "13",
                "start_pos": 91848811,
                "end_pos": 91609306,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000042122",
                        "url": "https://www.ensembl.org/id/ENSMUST00000042122"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000037115",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000037115"
                    }
                ]
            }
        }
    ],
    "glycosylation": [
        {
            "glytoucan_ac": "G49108TO",
            "type": "O-linked",
            "subtype": "O-GlcNAcylation",
            "site_category": "reported_with_glycan",
            "site_seq": "S",
            "relation": "attached",
            "comment": "O-GlcNAcylation",
            "start_pos": 350,
            "start_aa": "Ser",
            "end_pos": 350,
            "end_aa": "Ser",
            "residue": "Ser",
            "site_lbl": "Ser350",
            "evidence": [
                {
                    "id": "Q9CYZ8",
                    "database": "O-GlcNAc Atlas",
                    "url": "https://oglcnac.org/atlas/detail/Q9CYZ8"
                },
                {
                    "id": "32848054",
                    "database": "PubMed",
                    "url": "https://glygen.org/publication/PubMed/32848054"
                }
            ]
        },
        {
            "glytoucan_ac": "G49108TO",
            "type": "O-linked",
            "subtype": "O-GlcNAcylation",
            "site_category": "reported_with_glycan",
            "site_seq": "S",
            "relation": "attached",
            "comment": "O-GlcNAcylation",
            "start_pos": 352,
            "start_aa": "Ser",
            "end_pos": 352,
            "end_aa": "Ser",
            "residue": "Ser",
            "site_lbl": "Ser352",
            "evidence": [
                {
                    "id": "Q9CYZ8",
                    "database": "O-GlcNAc Atlas",
                    "url": "https://oglcnac.org/atlas/detail/Q9CYZ8"
                },
                {
                    "id": "32848054",
                    "database": "PubMed",
                    "url": "https://glygen.org/publication/PubMed/32848054"
                }
            ]
        },
        {
            "glytoucan_ac": "G49108TO",
            "type": "O-linked",
            "subtype": "O-GlcNAcylation",
            "site_category": "reported_with_glycan",
            "site_seq": "S",
            "relation": "attached",
            "comment": "O-GlcNAcylation",
            "start_pos": 354,
            "start_aa": "Ser",
            "end_pos": 354,
            "end_aa": "Ser",
            "residue": "Ser",
            "site_lbl": "Ser354",
            "evidence": [
                {
                    "id": "Q9CYZ8",
                    "database": "O-GlcNAc Atlas",
                    "url": "https://oglcnac.org/atlas/detail/Q9CYZ8"
                },
                {
                    "id": "32848054",
                    "database": "PubMed",
                    "url": "https://glygen.org/publication/PubMed/32848054"
                }
            ]
        },
        {
            "glytoucan_ac": "G49108TO",
            "type": "O-linked",
            "subtype": "O-GlcNAcylation",
            "site_category": "reported_with_glycan",
            "site_seq": "S",
            "relation": "attached",
            "comment": "O-GlcNAcylation",
            "start_pos": 356,
            "start_aa": "Ser",
            "end_pos": 356,
            "end_aa": "Ser",
            "residue": "Ser",
            "site_lbl": "Ser356",
            "evidence": [
                {
                    "id": "Q9CYZ8",
                    "database": "O-GlcNAc Atlas",
                    "url": "https://oglcnac.org/atlas/detail/Q9CYZ8"
                },
                {
                    "id": "32848054",
                    "database": "PubMed",
                    "url": "https://glygen.org/publication/PubMed/32848054"
                }
            ]
        },
        {
            "glytoucan_ac": "G49108TO",
            "type": "O-linked",
            "subtype": "O-GlcNAcylation",
            "site_category": "reported_with_glycan",
            "site_seq": "T",
            "relation": "attached",
            "comment": "O-GlcNAcylation",
            "start_pos": 358,
            "start_aa": "Thr",
            "end_pos": 358,
            "end_aa": "Thr",
            "residue": "Thr",
            "site_lbl": "Thr358",
            "evidence": [
                {
                    "id": "Q9CYZ8",
                    "database": "O-GlcNAc Atlas",
                    "url": "https://oglcnac.org/atlas/detail/Q9CYZ8"
                },
                {
                    "id": "32848054",
                    "database": "PubMed",
                    "url": "https://glygen.org/publication/PubMed/32848054"
                }
            ]
        },
        {
            "glytoucan_ac": "G49108TO",
            "type": "O-linked",
            "subtype": "O-GlcNAcylation",
            "site_category": "reported_with_glycan",
            "site_seq": "S",
            "relation": "attached",
            "comment": "O-GlcNAcylation",
            "start_pos": 360,
            "start_aa": "Ser",
            "end_pos": 360,
            "end_aa": "Ser",
            "residue": "Ser",
            "site_lbl": "Ser360",
            "evidence": [
                {
                    "id": "Q9CYZ8",
                    "database": "O-GlcNAc Atlas",
                    "url": "https://oglcnac.org/atlas/detail/Q9CYZ8"
                },
                {
                    "id": "32848054",
                    "database": "PubMed",
                    "url": "https://glygen.org/publication/PubMed/32848054"
                }
            ]
        }
    ],
    "phosphorylation": [
        {
            "start_pos": 321,
            "end_pos": 321,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Ser",
            "comment": "Phosphoserine",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q9CYZ8",
                    "url": "https://www.uniprot.org/uniprot/Q9CYZ8"
                },
                {
                    "database": "PubMed",
                    "id": "21183079",
                    "url": "https://glygen.org/publication/PubMed/21183079"
                },
                {
                    "database": "iPTMnet",
                    "id": "Q9CYZ8",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9CYZ8"
                }
            ],
            "site_lbl": "Ser321"
        },
        {
            "start_pos": 333,
            "end_pos": 333,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Thr",
            "comment": "Phosphothreonine",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q9CYZ8",
                    "url": "https://www.uniprot.org/uniprot/Q9CYZ8"
                },
                {
                    "database": "PubMed",
                    "id": "21183079",
                    "url": "https://glygen.org/publication/PubMed/21183079"
                },
                {
                    "database": "iPTMnet",
                    "id": "Q9CYZ8",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9CYZ8"
                }
            ],
            "site_lbl": "Thr333"
        }
    ],
    "glycation": [],
    "keywords": [
        "glycoprotein",
        "glycoprotein_reported_with_glycan"
    ],
    "publication": [
        {
            "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.",
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