{ "uniprot_canonical_ac": "Q99PL5-1", "uniprot_ac": "Q99PL5", "uniprot_id": "RRBP1_MOUSE", "mass": { "chemical_mass": 172879.0, "monoisotopic_mass": 172879.0 }, "refseq": { "ac": "NP_077243", "name": "ribosome-binding protein 1 isoform a", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_077243" }, "gene_names": [ { "name": "Rrbp1", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/Q99PL5", "id": "Q99PL5" }, { "name": "1700087N07Rik; 5730465C04Rik; ES/130; mKIAA1398; mRRp0; mRRp1.8; mRRp10; mRRp15a; mRRp15b; mRRp16.8; mRRp2; mRRp41; mRRp47; mRRp5.4; p180", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_077243", "id": "NP_077243" }, { "name": "Rrbp1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_077243", "id": "NP_077243" } ], "protein_names": [ { "name": "Ribosome-binding protein 1", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "Q99PL5" }, { "name": "RRp; mRRp; ribosome receptor protein", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_077243", "id": "NP_077243" }, { "name": "RRp", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q99PL5" }, { "name": "Ribosome receptor protein", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q99PL5" }, { "name": "mRRp", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q99PL5" }, { "name": "ribosome-binding protein 1 isoform a", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_077243", "id": "NP_077243" } ], "function": [ { "annotation": "Acts as a ribosome receptor and mediates interaction between the ribosome and the endoplasmic reticulum membrane.", "evidence": [ { "database": "UniProtKB", "id": "Q99PL5", "url": "https://www.uniprot.org/uniprot/Q99PL5#function" } ] }, { "annotation": "Mitochondria-ER cooperation: NLRX1 detects mitochondrial protein import stress and promotes mitophagy through the ER protein RRBP1.", "evidence": [ { "database": "RefSeq", "id": "NP_077243", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_077243" }, { "database": "PubMed", "id": "36170592", "url": "https://glygen.org/publication/PubMed/36170592" } ] } ], "disease": [], "snv": [ { "evidence": [ { "id": "rs265666792", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs265666792" } ], "glycoeffect": [ "n-glyco-sequon-gain" ], "start_pos": 439, "end_pos": 439, "sequence_org": "G", "sequence_mut": "S", "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-gain (NQG->NQS).", "chr_id": "2", "chr_pos": "143830851", "ref_nt": "T", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "G439", "keywords": [ "ebi", "germline" ] } ], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q99PL5", "url": "https://www.uniprot.org/uniprot/Q99PL5" } ], "common_name": "Mouse" } ], "gene": [ { "name": "Rrbp1", "url": "https://www.uniprot.org/uniprot/Q99PL5", "locus": { "chromosome": "2", "start_pos": 143789315, "end_pos": 143853183, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSMUSG00000027422", "url": "https://www.ensembl.org/id/ENSMUSG00000027422" } ] } } ], "crossref": [ { "id": "ENSMUSG00000027422", "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000027422", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "81910", "url": "https://www.ncbi.nlm.nih.gov/gene/81910", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q99PL5", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q99PL5*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR007794", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007794", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040248", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040248", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "mmu:81910", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:81910", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "1932395", "url": "http://www.informatics.jax.org/marker/MGI:1932395", "database": "MGI", "categories": [ "Organism-specific" ] }, { "id": "Q99PL5", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q99PL5", "database": "O-GlcNAc Database", "categories": [ "Glycoproteomics" ] }, { "id": "KRTQGEQ", "url": "https://omabrowser.org/oma/group/KRTQGEQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "3062132at2759", "url": "http://www.orthodb.org/?query=3062132at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18939", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18939", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18939:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18939:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05104", "url": "http://pfam.xfam.org/family/PF05104", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PR_Q99PL5", "url": "http://purl.obolibrary.org/obo/PR_Q99PL5", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_077243", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_077243", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A2AVJ7", "url": "https://www.uniprot.org/uniprot/A2AVJ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A2AVJ7-1", "url": "https://www.uniprot.org/uniprot/A2AVJ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q99PL5", "url": "https://www.uniprot.org/uniprot/Q99PL5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q99PL5-1", "url": "https://www.uniprot.org/uniprot/Q99PL5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q99PL5-10", "url": "https://www.uniprot.org/uniprot/Q99PL5-10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q99PL5-11", "url": "https://www.uniprot.org/uniprot/Q99PL5-11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q99PL5-12", "url": "https://www.uniprot.org/uniprot/Q99PL5-12", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q99PL5-2", "url": "https://www.uniprot.org/uniprot/Q99PL5-2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q99PL5-3", "url": "https://www.uniprot.org/uniprot/Q99PL5-3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q99PL5-4", "url": "https://www.uniprot.org/uniprot/Q99PL5-4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q99PL5-5", "url": "https://www.uniprot.org/uniprot/Q99PL5-5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q99PL5-6", "url": "https://www.uniprot.org/uniprot/Q99PL5-6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q99PL5-7", "url": "https://www.uniprot.org/uniprot/Q99PL5-7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q99PL5-8", "url": "https://www.uniprot.org/uniprot/Q99PL5-8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q99PL5-9", "url": "https://www.uniprot.org/uniprot/Q99PL5-9", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDIYDTQTLGVVVFGGFMVVSAIGIFLVSTFSMKETSYEEALANQRKEMAKTHHQKGEKKKKEKTVEKKGKTKKKEEKPNGKIPEHDLDPNVTIILKEPVRVSAVAVAPTSVHSSVGHTPIATVPAMPQEKLASSPKDRKKKEKKVAKVEPAVSSIVNSIQVLASKSAILEATPKEVPMVAVPPVGSKASSPATSSQGKKGQGAQNQAKKGEGAQNQGKKGEGAQNQAKKGEGAQNQAKKGEGAQNQGKKGEGAQNQAKKGEGGQNQAKKGEGAQNQGKKGEGAQNQGKKGEGAQNQAKKGEGAQNQAKKGEGAQNQGKKGEGAQNQSKKGEGAQNQAKKGEGGQNQAKKGEGAQNQAKKGEGAQNQAKKGEGVQNQAKKGVEGAQNQGKKGEANQNQAKKGEGGQNQTKKGEGPQNQGKKGEAAQKQDKKIEGAQNQGKKPEGTSNQGKKGEGAQNQGKKGEGAQNQSKKGEGAQNQAKKGEGGQNQAKKGEGAQNQAKKGEGAQNQAKKGEGVQNQAKKGVEGAQNQGKKGEANQNQAKKGEGGQNQTKKGEGPQNQGKKGEAAQKQDKKIEGAQNQGKKPEGTSNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGPQNQAKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKAEGVQSQSKKGEGTQNQGKKGDGNPNQGKKGEGASNQNRKTDTVANQGTKQEGVSNQVKKSEGSPNQGKKAEGAPNQGKKKDGSPSQAKKVDAAANQGKKSEMAPAQGQKASMVQSQEAPKQDAPAKKKSGSRKKGEPGPPDCDGPLFLPYKTLVSTVGSMVFSEGEAQRLIEILSEKTGVIQDTWHKATQKGDPVAILKRQLQEKEKLLATEQEDAAVAKSKLRELNKEMASEKAKAAAGEAKVKKQLVAREQEIAAVQARMQASYRDHVKEVQQLQGKIRTLQEQLENGPNTQLARLQQENSILRDALNQATSQVESKQNTELAKLRQELSKVNKELVEKSEASRQEEQQRKALEAKAATFEKQVLQLQASHKESEEALQKRLEEVTRELCRAQTSHANLRADAEKAQEQQQRVAELHSKLQSSEVEVKSKCEELSSLHGQLKEARAENSQLTERIRSIEALLEAGQAQDTQASHAEANQQQTRLKELESQVSCLEKETSELKEAMEQQKGKNNDLREKNWKAMEALALAERACEEKLRSLTQAKEESEKQLHLAEAQTKETLLALLPGLSISAHQNYAEWLQEFKEKGSELLKKPPTLEPSMDIVLKLREAEETQNSLQAECDQYRTILAETEGMLKDLQKSVEEEERVWKAKVGAAEEELHKSRVTVKHLEDIVEKLKGELESSDQVREHTSHLEAELEKHMAAASAECQNYAKEVAGLRQLLLESQSQLDEAKSEAQKQSDELALVRQQLSDMRSHVEDGDVAGSPAVPPAEQDPMKLKTQLERTEATLEAEQTRRQKLTAEFEEAQRTACRIQEELEKLRAAGPLESSGKEEITQLKERLEKEKRLTSDLGRAAIKLQELLKTTQEQLTKEKDTVKKLQEQLGKAEDGSSSKEGTSV", "length": 1605, "header": "sp|Q99PL5-1|RRBP1_MOUSE Isoform 1 of Ribosome-binding protein 1 OS=Mus musculus OX=10090 GN=Rrbp1 PE=1 SV=2 CANONICAL=Q99PL5-1" }, "isoforms": [ { "isoform_ac": "A2AVJ7-1", "url": "", "sequence": { "sequence": "MDIYDTQTLGVVVFGGFMVVSAIGIFLVSTFSMKETSYEEALANQRKEMAKTHHQKGEKKKKEKTVEKKGKTKKKEEKPNGKIPEHDLDPNVTIILKEPVRVSAVAVAPTSVHSSVGHTPIATVPAMPQEKLASSPKDRKKKEKKVAKVEPAVSSIVNSIQVLASKSAILEATPKEVPMVAVPPVGSKASSPATSSQGKKGQGAQNQAKKGEGAQNQGKKGEGAQNQAKKGEGAQNQAKKGEGAQNQGKKGEGAQNQAKKGEGGQNQAKKGEGAQNQGKKGEGAQNQGKKGEGAQNQAKKGEGAQNQAKKGEGAQNQGKKGEGAQNQSKKGEGAQNQAKKGEGGQNQAKKGEGAQNQAKKGEGAQNQAKKGEGVQNQAKKGVEGAQNQGKKGEANQNQAKKGEGGQNQTKKGEGPQNQGKKGEAAQKQDKKIEGAQNQGKKPEGTSNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGPQNQAKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKAEGVQSQSKKGEGTQNQGKKGDGNPNQGKKGEGASNQNRKTDTVANQGTKQEGVSNQVKKSEGSPNQGKKAEGAPNQGKKKDGSPSQAKKVDAAANQGKKSEMAPAQGQKASMVQSQEAPKQDAPAKKKSGSRKKGEPGPPDCDGPLFLPYKTLVSTVGSMVFSEGEAQRLIEILSEKTGVIQDTWHKATQKGDPVAILKRQLEEKEKLLATEQEDAAVAKSKLRELNKEMASEKAKAAAGEAKVKKQLVAREQEIAAVQARMQASYRDHVKEVQQLQGKIRTLQEQLENGPNTQLARLQQENSILRDALNQATSQVESKQNTELAKLRQELSKVNKELVEKSEASRQEEQQRKALEAKAATFEKQVLQLQASHKESEEALQKRLEEVTRELCRAQTSHANLRADAEKAQEQQQRVAELHSKLQSSEVEVKSKCEELSSLHGQLKEARAENSQLTERIRSIEALLEAGQAQDTQASHAEANQQQTRLKELESQVSCLEKETSELKEAMEQQKGKNNDLREKNWKAMEALALAERACEEKLRSLTQAKEESEKQLHLAEAQTKETLLALLPGLSISAHQNYAEWLQEFKEKGSELLKKPPTLEPSMDIVLKLREAEETQNSLQAECDQYRTILAETEGMLKDLQKSVEEEERVWKAKVGAAEEELHKSRVTVKHLEDIVEKLKGELESSDQVREHTSHLEAELEKHMAAASAECQNYAKEVAGLRQLLLESQSQLDEAKSEAQKQSDELALVRQQLSDMRSHVEDGDVAGSPAVPPAEQDPMKLKTQLERTEATLEAEQTRRQKLTAEFEEAQRTACRIQEELEKLRAAGPLESSGKEEITQLKERLEKEKRLTSDLGRAAIKLQELLKTTQEQLTKEKDTVKKLQEQLGKAEDGSSSKEGTSV", "length": 1464, "header": "tr|A2AVJ7-1|RRBP1_MOUSE Computationally mapped isoform of Ribosome-binding protein 1 OS=Mus musculus OX=10090 GN=Rrbp1 PE=1 SV=1 CANONICAL=Q99PL5-1" }, "locus": { "chromosome": "2", "start_pos": 143832165, "end_pos": 143789814, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000016072.12", "url": "https://www.ensembl.org/id/ENSMUST00000016072.12" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000016072.6", "url": "https://www.ensembl.org/id/ENSMUSP00000016072.6" } ] } }, { "isoform_ac": "Q99PL5-1", "url": "", "sequence": { "sequence": "MDIYDTQTLGVVVFGGFMVVSAIGIFLVSTFSMKETSYEEALANQRKEMAKTHHQKGEKKKKEKTVEKKGKTKKKEEKPNGKIPEHDLDPNVTIILKEPVRVSAVAVAPTSVHSSVGHTPIATVPAMPQEKLASSPKDRKKKEKKVAKVEPAVSSIVNSIQVLASKSAILEATPKEVPMVAVPPVGSKASSPATSSQGKKGQGAQNQAKKGEGAQNQGKKGEGAQNQAKKGEGAQNQAKKGEGAQNQGKKGEGAQNQAKKGEGGQNQAKKGEGAQNQGKKGEGAQNQGKKGEGAQNQAKKGEGAQNQAKKGEGAQNQGKKGEGAQNQSKKGEGAQNQAKKGEGGQNQAKKGEGAQNQAKKGEGAQNQAKKGEGVQNQAKKGVEGAQNQGKKGEANQNQAKKGEGGQNQTKKGEGPQNQGKKGEAAQKQDKKIEGAQNQGKKPEGTSNQGKKGEGAQNQGKKGEGAQNQSKKGEGAQNQAKKGEGGQNQAKKGEGAQNQAKKGEGAQNQAKKGEGVQNQAKKGVEGAQNQGKKGEANQNQAKKGEGGQNQTKKGEGPQNQGKKGEAAQKQDKKIEGAQNQGKKPEGTSNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGPQNQAKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKAEGVQSQSKKGEGTQNQGKKGDGNPNQGKKGEGASNQNRKTDTVANQGTKQEGVSNQVKKSEGSPNQGKKAEGAPNQGKKKDGSPSQAKKVDAAANQGKKSEMAPAQGQKASMVQSQEAPKQDAPAKKKSGSRKKGEPGPPDCDGPLFLPYKTLVSTVGSMVFSEGEAQRLIEILSEKTGVIQDTWHKATQKGDPVAILKRQLQEKEKLLATEQEDAAVAKSKLRELNKEMASEKAKAAAGEAKVKKQLVAREQEIAAVQARMQASYRDHVKEVQQLQGKIRTLQEQLENGPNTQLARLQQENSILRDALNQATSQVESKQNTELAKLRQELSKVNKELVEKSEASRQEEQQRKALEAKAATFEKQVLQLQASHKESEEALQKRLEEVTRELCRAQTSHANLRADAEKAQEQQQRVAELHSKLQSSEVEVKSKCEELSSLHGQLKEARAENSQLTERIRSIEALLEAGQAQDTQASHAEANQQQTRLKELESQVSCLEKETSELKEAMEQQKGKNNDLREKNWKAMEALALAERACEEKLRSLTQAKEESEKQLHLAEAQTKETLLALLPGLSISAHQNYAEWLQEFKEKGSELLKKPPTLEPSMDIVLKLREAEETQNSLQAECDQYRTILAETEGMLKDLQKSVEEEERVWKAKVGAAEEELHKSRVTVKHLEDIVEKLKGELESSDQVREHTSHLEAELEKHMAAASAECQNYAKEVAGLRQLLLESQSQLDEAKSEAQKQSDELALVRQQLSDMRSHVEDGDVAGSPAVPPAEQDPMKLKTQLERTEATLEAEQTRRQKLTAEFEEAQRTACRIQEELEKLRAAGPLESSGKEEITQLKERLEKEKRLTSDLGRAAIKLQELLKTTQEQLTKEKDTVKKLQEQLGKAEDGSSSKEGTSV", "length": 1605, "header": "sp|Q99PL5-1|RRBP1_MOUSE Isoform 1 of Ribosome-binding protein 1 OS=Mus musculus OX=10090 GN=Rrbp1 PE=1 SV=2 CANONICAL=Q99PL5-1" }, "locus": {} }, { "isoform_ac": "Q99PL5-10", "url": "", "sequence": { "sequence": "MDIYDTQTLGVVVFGGFMVVSAIGIFLVSTFSMKETSYEEALANQRKEMAKTHHQKGEKKKKEKTVEKKGKTKKKEEKPNGKIPEHDLDPNVTIILKEPVRVSAVAVAPTSVHSSVGHTPIATVPAMPQEKLASSPKDRKKKEKKVAKVEPAVSSIVNSIQVLASKSAILEATPKEVPMVAVPPVGSKASSPATSSQAKKVDAAANQGKKSEMAPAQGQKASMVQSQEAPKQDAPAKKKSGSRKKGEPVC", "length": 250, "header": "sp|Q99PL5-10|RRBP1_MOUSE Isoform 10 of Ribosome-binding protein 1 OS=Mus musculus OX=10090 GN=Rrbp1 PE=1 SV=2 CANONICAL=Q99PL5-1" }, "locus": {} }, { "isoform_ac": "Q99PL5-11", "url": "", "sequence": { "sequence": "MDIYDTQTLGVVVFGGFMVVSAIGIFLVSTFSMKETSYEEALANQRKEMAKTHHQKGEKKKKEKTVEKKGKTKKKEEKPNGKIPEHDLDPNVTIILKEPVRVSAVAVAPTSVHSSVGHTPIATVPAMPQEKLASSPKDRKKKEKKVAKVEPAVSSIVNSIQVLASKSAILEATPKEAKKVDAAANQGKKSEMAPAQGQKASMVQSQEAPKQDAPAKKKSGSRKKGEPVC", "length": 229, "header": "sp|Q99PL5-11|RRBP1_MOUSE Isoform 11 of Ribosome-binding protein 1 OS=Mus musculus OX=10090 GN=Rrbp1 PE=1 SV=2 CANONICAL=Q99PL5-1" }, "locus": {} }, { "isoform_ac": "Q99PL5-12", "url": "", "sequence": { "sequence": "MDIYDTQTLGVVVFGGFMVVSAIGIFLVSTFSMKETSYEEALANQRKEMAKTHHQKGEKKKKEKTVEKKGKTKKKEEKPNGKIPEHDLDPNVTIILKEPVRVSAVAVAPTSVHSSVGHTPIATVPAMPQEKLASSPKDRKKKEKKVAKVEPAVSSIVNSIQVLASKSAILEATPKEGQKASMVQSQEAPKQDAPAKKKSGSRKKGEPVC", "length": 209, "header": "sp|Q99PL5-12|RRBP1_MOUSE Isoform 12 of Ribosome-binding protein 1 OS=Mus musculus OX=10090 GN=Rrbp1 PE=1 SV=2 CANONICAL=Q99PL5-1" }, "locus": {} }, { "isoform_ac": "Q99PL5-2", "url": "", "sequence": { "sequence": "MDIYDTQTLGVVVFGGFMVVSAIGIFLVSTFSMKETSYEEALANQRKEMAKTHHQKGEKKKKEKTVEKKGKTKKKEEKPNGKIPEHDLDPNVTIILKEPVRVSAVAVAPTSVHSSVGHTPIATVPAMPQEKLASSPKDRKKKEKKVAKVEPAVSSIVNSIQVLASKSAILEATPKEVPMVAVPPVGSKASSPATSSQGKKGQGAQNQAKKGEGAQNQGKKGEGAQNQAKKGEGAQNQAKKGEGAQNQGKKGEGAQNQAKKGEGGQNQAKKGEGAQNQGKKGEGAQNQGKKGEGAQNQAKKGEGAQNQAKKGEGAQNQGKKGEGAQNQSKKGEGAQNQAKKGEGGQNQAKKGEGAQNQAKKGEGAQNQAKKGEGVQNQAKKGVEGAQNQGKKGEANQNQAKKGEGGQNQTKKGEGPQNQGKKGEAAQKQDKKIEGAQNQGKKPEGTSNQGKKGEGAQNQGKKGEGAQNQSKKGEGAQNQAKKGEGGQNQAKKGEGAQNQAKKGEGAQNQAKKGEGVQNQAKKGVEGAQNQGKKGEANQNQAKKGEGGQNQTKKGEGPQNQGKKGEAAQKQDKKIEGAQNQGKKPEGTSNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGPQNQAKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKAEGVQSQSKKGEGTQNQGKKGDGNPNQGKKGEGASNQNRKTDTVANQGTKQEGVSNQVKKSEGSPNQGKKAEGAPNQGKKKDGSPSQAKKVDAAANQGKKSEMAPAQGQKASMVQSQEAPKQDAPAKKKSGSRKKGEPVC", "length": 842, "header": "sp|Q99PL5-2|RRBP1_MOUSE Isoform 2 of Ribosome-binding protein 1 OS=Mus musculus OX=10090 GN=Rrbp1 PE=1 SV=2 CANONICAL=Q99PL5-1" }, "locus": {} }, { "isoform_ac": "Q99PL5-3", "url": "", "sequence": { "sequence": "MDIYDTQTLGVVVFGGFMVVSAIGIFLVSTFSMKETSYEEALANQRKEMAKTHHQKGEKKKKEKTVEKKGKTKKKEEKPNGKIPEHDLDPNVTIILKEPVRVSAVAVAPTSVHSSVGHTPIATVPAMPQEKLASSPKDRKKKEKKVAKVEPAVSSIVNSIQVLASKSAILEATPKEVPMVAVPPVGSKASSPATSSQGKKGQGAQNQAKKGEGAQNQGKKGEGAQNQAKKGEGAQNQAKKGEGAQNQGKKGEGAQNQAKKGEGGQNQAKKGEGAQNQGKKGEGAQNQGKKGEGAQNQAKKGEGAQNQAKKGEGAQNQGKKGEGAQNQSKKGEGAQNQAKKGEGGQNQAKKGEGAQNQAKKGEGAQNQAKKGEGVQNQAKKGVEGAQNQGKKGEANQNQAKKGEGGQNQTKKGEGPQNQGKKGEAAQKQDKKIEGAQNQGKKPEGTSNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGPQNQAKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKAEGVQSQSKKGEGTQNQGKKGDGNPNQGKKGEGASNQNRKTDTVANQGTKQEGVSNQVKKSEGSPNQGKKAEGAPNQGKKKDGSPSQAKKVDAAANQGKKSEMAPAQGQKASMVQSQEAPKQDAPAKKKSGSRKKGEPVC", "length": 701, "header": "sp|Q99PL5-3|RRBP1_MOUSE Isoform 3 of Ribosome-binding protein 1 OS=Mus musculus OX=10090 GN=Rrbp1 PE=1 SV=2 CANONICAL=Q99PL5-1" }, "locus": { "chromosome": "2", "start_pos": 143832165, "end_pos": 143828085, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000037875", "url": "https://www.ensembl.org/id/ENSMUST00000037875" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000040560", "url": "https://www.ensembl.org/id/ENSMUSP00000040560" } ] } }, { "isoform_ac": "Q99PL5-4", "url": "", "sequence": { "sequence": "MDIYDTQTLGVVVFGGFMVVSAIGIFLVSTFSMKETSYEEALANQRKEMAKTHHQKGEKKKKEKTVEKKGKTKKKEEKPNGKIPEHDLDPNVTIILKEPVRVSAVAVAPTSVHSSVGHTPIATVPAMPQEKLASSPKDRKKKEKKVAKVEPAVSSIVNSIQVLASKSAILEATPKEVPMVAVPPVGSKASSPATSSQGKKGQGAQNQAKKGEGAQNQGKKGEGAQNQAKKGEGAQNQAKKGEGAQNQGKKGEGAQNQAKKGEGGQNQAKKGEGAQNQGKKGEGAQNQGKKGEGAQNQAKKGEGAQNQAKKGEGAQNQGKKGEGAQNQSKKGEGAQNQAKKGEGGQNQAKKGEGAQNQAKKGEGAQNQAKKGEGVQNQAKKGVEGAQNQGKKGEANQNQAKKGEGGQNQTKKGEGPQNQGKKGEAAQKQDKKIEGAQNQGKKPEGTSNQGKKGEGAQNQGKKGEGAQNQAKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKAEGVQSQSKKGEGTQNQGKKGDGNPNQGKKGEGASNQNRKTDTVANQGTKQEGVSNQVKKSEGSPNQGKKAEGAPNQGKKKDGSPSQAKKVDAAANQGKKSEMAPAQGQKASMVQSQEAPKQDAPAKKKSGSRKKGEPVC", "length": 641, "header": "sp|Q99PL5-4|RRBP1_MOUSE Isoform 4 of Ribosome-binding protein 1 OS=Mus musculus OX=10090 GN=Rrbp1 PE=1 SV=2 CANONICAL=Q99PL5-1" }, "locus": {} }, { "isoform_ac": "Q99PL5-5", "url": "", "sequence": { "sequence": "MDIYDTQTLGVVVFGGFMVVSAIGIFLVSTFSMKETSYEEALANQRKEMAKTHHQKGEKKKKEKTVEKKGKTKKKEEKPNGKIPEHDLDPNVTIILKEPVRVSAVAVAPTSVHSSVGHTPIATVPAMPQEKLASSPKDRKKKEKKVAKVEPAVSSIVNSIQVLASKSAILEATPKEVPMVAVPPVGSKASSPATSSQGKKGQGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGPQNQAKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKAEGVQSQSKKGEGTQNRKTDTVANQGTKQEGVSNQVKKSEGSPNQGKKAEGAPNQGKKKDGSPSQAKKVDAAANQGKKSEMAPAQGQKASMVQSQEAPKQDAPAKKKSGSRKKGEPVC", "length": 398, "header": "sp|Q99PL5-5|RRBP1_MOUSE Isoform 5 of Ribosome-binding protein 1 OS=Mus musculus OX=10090 GN=Rrbp1 PE=1 SV=2 CANONICAL=Q99PL5-1" }, "locus": {} }, { "isoform_ac": "Q99PL5-6", "url": "", "sequence": { "sequence": "MDIYDTQTLGVVVFGGFMVVSAIGIFLVSTFSMKETSYEEALANQRKEMAKTHHQKGEKKKKEKTVEKKGKTKKKEEKPNGKIPEHDLDPNVTIILKEPVRVSAVAVAPTSVHSSVGHTPIATVPAMPQEKLASSPKDRKKKEKKVAKVEPAVSSIVNSIQVLASKSAILEATPKEVPMVAVPPVGSKASSPATSSQGKKGQGAQNQAKKGEGAQNQGKKGEGAQNQAKKGEGAQNQAKKGEGAQNQGKKGEGAQNQAKKGEGGQNQAKKGEGASNQNRKTDTVANQGTKQEGVSNQVKKSEGSPNQGKKAEGAPNQGKKKDGSPSQAKKVDAAANQGKKSEMAPAQGQKASMVQSQEAPKQDAPAKKKSGSRKKGEPVC", "length": 380, "header": "sp|Q99PL5-6|RRBP1_MOUSE Isoform 6 of Ribosome-binding protein 1 OS=Mus musculus OX=10090 GN=Rrbp1 PE=1 SV=2 CANONICAL=Q99PL5-1" }, "locus": {} }, { "isoform_ac": "Q99PL5-7", "url": "", "sequence": { "sequence": "MDIYDTQTLGVVVFGGFMVVSAIGIFLVSTFSMKETSYEEALANQRKEMAKTHHQKGEKKKKEKTVEKKGKTKKKEEKPNGKIPEHDLDPNVTIILKEPVRVSAVAVAPTSVHSSVGHTPIATVPAMPQEKLASSPKDRKKKEKKVAKVEPAVSSIVNSIQVLASKSAILEATPKEVPMVAVPPVGSKASSPATSSQGKKGQGAQNQAKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKAEGVQSQSKKGEGTQNQGKKGDGNPNQGKKGEGASNQNRKTDTVANQGTKQEGVSNQVKKSEGSPNQGKKAEGAPNQGKKKDGSPSQAKKVDAAANQGKKSEMAPAQGQKASMVQSQEAPKQDAPAKKKSGSRKKGEPVC", "length": 380, "header": "sp|Q99PL5-7|RRBP1_MOUSE Isoform 7 of Ribosome-binding protein 1 OS=Mus musculus OX=10090 GN=Rrbp1 PE=1 SV=2 CANONICAL=Q99PL5-1" }, "locus": {} }, { "isoform_ac": "Q99PL5-8", "url": "", "sequence": { "sequence": "MDIYDTQTLGVVVFGGFMVVSAIGIFLVSTFSMKETSYEEALANQRKEMAKTHHQKGEKKKKEKTVEKKGKTKKKEEKPNGKIPEHDLDPNVTIILKEPVRVSAVAVAPTSVHSSVGHTPIATVPAMPQEKLASSPKDRKKKEKKVAKVEPAVSSIVNSIQVLASKSAILEATPKEVPMVAVPPVGSKASSPATSSQGKKGQGAQNQAKKGDGNPNQGKKGEGASNQNRKTDTVANQGTKQEGVSNQVKKSEGSPNQGKKAEGAPNQGKKKDGSPSQAKKVDAAANQGKKSEMAPAQGQKASMVQSQEAPKQDAPAKKKSGSRKKGEPVC", "length": 330, "header": "sp|Q99PL5-8|RRBP1_MOUSE Isoform 8 of Ribosome-binding protein 1 OS=Mus musculus OX=10090 GN=Rrbp1 PE=1 SV=2 CANONICAL=Q99PL5-1" }, "locus": {} }, { "isoform_ac": "Q99PL5-9", "url": "", "sequence": { "sequence": "MDIYDTQTLGVVVFGGFMVVSAIGIFLVSTFSMKETSYEEALANQRKEMAKTHHQKGEKKKKEKTVEKKGKTKKKEEKPNGKIPEHDLDPNVTIILKEPVRVSAVAVAPTSVHSSVGHTPIATVPAMPQEKLASSPKDRKKKEKKVAKVEPAVSSIVNSIQVLASKSAILEATPKEVPMVAVPPVGSKASSPATSSQGKKGQGAQNQAPNQGKKAEGAPNQGKKKDGSPSQAKKVDAAANQGKKSEMAPAQGQKASMVQSQEAPKQDAPAKKKSGSRKKGEPVC", "length": 284, "header": "sp|Q99PL5-9|RRBP1_MOUSE Isoform 9 of Ribosome-binding protein 1 OS=Mus musculus OX=10090 GN=Rrbp1 PE=1 SV=2 CANONICAL=Q99PL5-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "site_category": "reported_with_glycan", "site_seq": "T", "relation": "attached", "comment": "O-GlcNAcylation", "start_pos": 93, "start_aa": "Thr", "end_pos": 93, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr93", "evidence": [ { "id": "Q99PL5", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q99PL5" }, { "id": "36288343", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/36288343" }, { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "34418053", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34418053" } ] }, { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "site_category": "reported_with_glycan", "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "evidence": [ { "id": "Q99PL5", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q99PL5" }, { "id": "34887587", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/34887587" } ] } ], "phosphorylation": [ { "start_pos": 111, "end_pos": 111, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q99PL5", "url": "https://www.uniprot.org/uniprot/Q99PL5" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q99PL5", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99PL5" } ], "site_lbl": "Ser111" }, { "start_pos": 1162, "end_pos": 1162, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q99PL5", "url": "https://www.uniprot.org/uniprot/Q99PL5" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q99PL5", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99PL5" } ], "site_lbl": "Ser1162" }, { "start_pos": 1178, "end_pos": 1178, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q99PL5", "url": "https://www.uniprot.org/uniprot/Q99PL5" } ], "site_lbl": "Ser1178" }, { "start_pos": 159, "end_pos": 159, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q99PL5", "url": "https://www.uniprot.org/uniprot/Q99PL5" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q99PL5", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99PL5" } ], "site_lbl": "Ser159" }, { "start_pos": 165, "end_pos": 165, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q99PL5", "url": "https://www.uniprot.org/uniprot/Q99PL5" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q99PL5", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99PL5" } ], "site_lbl": "Ser165" }, { "start_pos": 786, "end_pos": 786, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q99PL5", "url": "https://www.uniprot.org/uniprot/Q99PL5" } ], "site_lbl": "Ser786" }, { "start_pos": 818, "end_pos": 818, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q99PL5", "url": "https://www.uniprot.org/uniprot/Q99PL5" } ], "site_lbl": "Ser818" } ], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_reported_with_glycan" ], "publication": [ { "title": "Identification and characterization of multiple isoforms of a mouse ribosome receptor.", "journal": "Gene", "date": "2000", "authors": "Kim YJ, Lee MC, Kim SJ, Chun JY", "evidence": [ { "database": "UniProtKB", "id": "Q99PL5", "url": "https://www.uniprot.org/uniprot/Q99PL5" } ], "reference": [ { "type": "PubMed", "id": "11167022", "url": "https://glygen.org/publication/PubMed/11167022" } ] }, { "title": "Specific phosphopeptide enrichment with immobilized titanium ion affinity chromatography adsorbent for phosphoproteome analysis.", "journal": "J. Proteome Res.", "date": "2008", "authors": "Zhou H, Ye M, Dong J, Han G, Jiang X, Wu R, Zou H", "evidence": [ { "database": "UniProtKB", "id": "A2AVJ7", "url": "https://www.uniprot.org/uniprot/A2AVJ7" }, { "database": "UniProtKB", "id": "Q99PL5", "url": "https://www.uniprot.org/uniprot/Q99PL5" } ], "reference": [ { "type": "PubMed", "id": "18630941", "url": "https://glygen.org/publication/PubMed/18630941" } ] }, { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q99PL5", "url": "https://www.uniprot.org/uniprot/Q99PL5" }, { "database": "iPTMnet", "id": "Q99PL5", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q99PL5" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q99PL5", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q99PL5" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] }, { "title": "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.", "journal": "Mol. Cell", "date": "2013", "authors": "Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y", "evidence": [ { "database": "UniProtKB", "id": "A2AVJ7", "url": "https://www.uniprot.org/uniprot/A2AVJ7" }, { "database": "UniProtKB", "id": "Q99PL5", "url": "https://www.uniprot.org/uniprot/Q99PL5" } ], "reference": [ { "type": "PubMed", "id": "23806337", "url": "https://glygen.org/publication/PubMed/23806337" } ] }, { "title": "O-GlcNAcylation Is Essential for Rapid Pomc Expression and Cell Proliferation in Corticotropic Tumor Cells.", "journal": "Endocrinology", "date": "2021", "authors": "Massman LJ, Pereckas M, Zwagerman NT, Olivier-Van Stichelen S", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q99PL5", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q99PL5" } ], "reference": [ { "type": "PubMed", "id": "34418053", "url": "https://glygen.org/publication/PubMed/34418053" } ] }, { "title": "Dynamic eIF3a O-GlcNAcylation controls translation reinitiation during nutrient stress.", "journal": "Nature chemical biology", "date": "2022", "authors": "Shu XE, Mao Y, Jia L, Qian SB", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q99PL5", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q99PL5" } ], "reference": [ { "type": "PubMed", "id": "34887587", "url": "https://glygen.org/publication/PubMed/34887587" } ] }, { "title": "Mitochondria-ER cooperation: NLRX1 detects mitochondrial protein import stress and promotes mitophagy through the ER protein RRBP1.", "journal": "Autophagy", "date": "2022-10-04", "authors": "Killackey Samuel A, Bi Yuntian, Philpott Dana J, Arnoult Damien, Girardin Stephen E", "evidence": [ { "database": "RefSeq", "id": "NP_077243", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_077243" } ], "reference": [ { "type": "PubMed", "id": "36170592", "url": "https://glygen.org/publication/PubMed/36170592" } ] }, { "title": "First comprehensive identification of cardiac proteins with putative increased O-GlcNAc levels during pressure overload hypertrophy.", "journal": "PloS one", "date": "2022", "authors": "Zhu Wei Zhong, Palazzo Teresa, Zhou Mowei, Ledee Dolena, Olson Heather M, Pa\u0161a-Toli\u0107 Ljiljana, Olson Aaron K", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q99PL5", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q99PL5" } ], "reference": [ { "type": "PubMed", "id": "36288343", "url": "https://glygen.org/publication/PubMed/36288343" } ] } ], "pathway": [ { "id": "mmu:81910", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:81910", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1M853-1", "protein_name": "Ribosome binding protein 1", "gene_name": "Rrbp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDIYDTQTLGVVVFGGFMVVSAIGIFLVSTFSMKETSYEEALANQRKEMAKTHHQKGEKKKKEKTVEKKGKTKKKEEKPNGKIPEHDLDPNVTIILKEPMRVPAVAVAPTSVHSSVGRTPVATVPAMPQEKLASSPKDKKKKEKKVAKVEPAVSSIVNSIQVLASKSAILEASPKEVPMVAVPPVGSKASAPATSSQGKKGQGAQNQAKKGEGAQNQAKKGEGVQNQAKKGEGAQNQVKKGEGAQNQAKKGEGAQNQAKKGEGTQNQAKKGEGAQNQGKKGEGAQNQAKKGEGAQNQAKKGEGAQNQAKKGEGAQNQAKKGEGGQNQAKKGEGAQNQAKKGEGAQNQAKKGEGVQNQAKKGVEGAQNQGKKGEANQNQAKKGEGGQNQTKKGEGLQNQGKKGEATQKQDKKIEGAQNQGKKPEGTPNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGSPSQNIKVEGMQNQGRKAEGTPAQGKKMEAAQNQGKKAEGVQSQGKKGEGSQNQGKKGDGNPNQGKKGEGAPNQNRKTDTVANQGTKTEGVSNQVKKSEGSPNQGKKAEGAPNQGKKVEGSPNQAKKVDAAAGQGKKSEMTPAQGKNASMVQSQEAPKQEAPAKKKSKKKGEPGPPDCDSPLFLPYKTLVSTVGSMVFSEGEAQRLIEILSEKTGVIQDTWHKATQKGDPVAVLKRQLEEKEKLLATEQEDAAVAKSKLRELNKEMASEKAKAAAGEAKVKKQLVAREQEIAAVQARMQASYQDHVKEVQQLQGKIRTLQEQLENGPNTQLARLQQENSILRDALNQATSQVESKQNTELAKLRQELSKVNKELVEKSEASRQEEQQRKALEAKAATFEKQILQLQASHKESEEALQKRLEEVTRELCRAQTSHANLRADAEKAQEQQQRVAELHSKLQSSEVEVKSKCEELSDLHGQLKEARAENSQLTERIRSIEALLEAGQAQDSQASRAEADQQQTRLKELESQVSCLEKETSELKEAMEQQKGKNNDLREKNWKAMEALALAERACEEKLRSLTQAKEESEKQLHLAEAQTKEVLLALLPELSIPAHQNYADWLQEVKEKGSELLKKPPVSVEPSLDIVSKLREAEETQNSLQAECDQYRTILAETEGMLKDLQKSVEEEERVWKAKVGAAEEELQKSRFTVKHLEDLVEKLRGELESSDQVREHTSHLEAELEKHMAAASAECQNYAKEVAGLRQLLLDSQSQLEEAKSEAQKQSNELALVRQQLSDMRSHVEDGDVAGSPAVPPAEQDPVKLKTQLERTEATLEDEQTRRQKLTAEFEEAQSTACRLQEELEKLRAAGPLESSGIEEVTQLKERLEKEKRLTSDLGRAATKLQELLKTTQEQLTKEKDTVKKLQEQLGKAEDGSSSKEGTSV", "length": 1453 }, "evidence": [ { "id": "45225503", "url": "http://www.informatics.jax.org/homology/45225503", "database": "MGI" } ], "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9P2E9-1", "protein_name": "Ribosome-binding protein 1", "gene_name": "RRBP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDIYDTQTLGVVVFGGFMVVSAIGIFLVSTFSMKETSYEEALANQRKEMAKTHHQKVEKKKKEKTVEKKGKTKKKEEKPNGKIPDHDPAPNVTVLLREPVRAPAVAVAPTPVQPPIIVAPVATVPAMPQEKLASSPKDKKKKEKKVAKVEPAVSSVVNSIQVLTSKAAILETAPKEVPMVVVPPVGAKGNTPATGTTQGKKAEGTQNQSKKAEGAPNQGRKAEGTPNQGKKTEGTPNQGKKAEGTPNQGKKAEGTPNQGKKAEGAQNQGKKVDTTPNQGKKVEGAPTQGRKAEGAQNQAKKVEGAQNQGKKAEGAQNQGKKGEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKVEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGKKVEGAQNQGKKAEGAQNQGKKAEGAQNQGKKAEGAQNQGQKGEGAQNQGKKTEGAQGKKAERSPNQGKKGEGAPIQGKKADSVANQGTKVEGITNQGKKAEGSPSEGKKAEGSPNQGKKADAAANQGKKTESASVQGRNTDVAQSPEAPKQEAPAKKKSGSKKKGEPGPPDADGPLYLPYKTLVSTVGSMVFNEGEAQRLIEILSEKAGIIQDTWHKATQKGDPVAILKRQLEEKEKLLATEQEDAAVAKSKLRELNKEMAAEKAKAAAGEAKVKKQLVAREQEITAVQARMQASYREHVKEVQQLQGKIRTLQEQLENGPNTQLARLQQENSILRDALNQATSQVESKQNAELAKLRQELSKVSKELVEKSEAVRQDEQQRKALEAKAAAFEKQVLQLQASHRESEEALQKRLDEVSRELCHTQSSHASLRADAEKAQEQQQQMAELHSKLQSSEAEVRSKCEELSGLHGQLQEARAENSQLTERIRSIEALLEAGQARDAQDVQASQAEADQQQTRLKELESQVSGLEKEAIELREAVEQQKVKNNDLREKNWKAMEALATAEQACKEKLLSLTQAKEESEKQLCLIEAQTMEALLALLPELSVLAQQNYTEWLQDLKEKGPTLLKHPPAPAEPSSDLASKLREAEETQSTLQAECDQYRSILAETEGMLRDLQKSVEEEEQVWRAKVGAAEEELQKSRVTVKHLEEIVEKLKGELESSDQVREHTSHLEAELEKHMAAASAECQNYAKEVAGLRQLLLESQSQLDAAKSEAQKQSDELALVRQQLSEMKSHVEDGDIAGAPASSPEAPPAEQDPVQLKTQLEWTEAILEDEQTQRQKLTAEFEEAQTSACRLQEELEKLRTAGPLESSETEEASQLKERLEKEKKLTSDLGRAATRLQELLKTTQEQLAREKDTVKKLQEQLEKAEDGSSSKEGTSV", "length": 1410 }, "evidence": [ { "id": "45225503", "url": "http://www.informatics.jax.org/homology/45225503", "database": "MGI" } ], "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q99PL5", "url": "https://www.uniprot.org/uniprot/Q99PL5" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "Q99PL5", "url": "https://www.uniprot.org/uniprot/Q99PL5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q99PL5", "url": "https://www.uniprot.org/uniprot/Q99PL5" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q99PL5", "url": "https://www.uniprot.org/uniprot/Q99PL5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 326, "end_pos": 328, "annotation": "n_glycosylation_sequon" }, { "start_pos": 407, "end_pos": 409, "annotation": "n_glycosylation_sequon" }, { "start_pos": 467, "end_pos": 469, "annotation": "n_glycosylation_sequon" }, { "start_pos": 548, "end_pos": 550, "annotation": "n_glycosylation_sequon" }, { "start_pos": 91, "end_pos": 93, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "synthesized_glycans": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.mgi", "label": "MGI Homologs" } ], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 2 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 2 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 7 }, { "field": "total_sites", "count": 7 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 9 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }