{
    "uniprot_canonical_ac": "Q99N87-1",
    "uniprot_ac": "Q99N87",
    "uniprot_id": "RT05_MOUSE",
    "mass": {
        "chemical_mass": 48207.0,
        "monoisotopic_mass": 48207.0
    },
    "refseq": {
        "ac": "NP_084239",
        "name": "small ribosomal subunit protein uS5m",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_084239"
    },
    "gene_names": [
        {
            "name": "Mrps5",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/Q99N87",
            "id": "Q99N87"
        },
        {
            "name": "1620401I16Rik",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_084239",
            "id": "NP_084239"
        },
        {
            "name": "Mrps5",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_084239",
            "id": "NP_084239"
        }
    ],
    "protein_names": [
        {
            "name": "Small ribosomal subunit protein uS5m",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "Q99N87"
        },
        {
            "name": "28S ribosomal protein S5, mitochondrial; S5mt; MRP-S5",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_084239",
            "id": "NP_084239"
        },
        {
            "name": "28S ribosomal protein S5, mitochondrial",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q99N87"
        },
        {
            "name": "MRP-S5",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q99N87"
        },
        {
            "name": "S5mt",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q99N87"
        },
        {
            "name": "small ribosomal subunit protein uS5m",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_084239",
            "id": "NP_084239"
        }
    ],
    "function": [
        {
            "annotation": "Phenotype of Mrps5-Associated Phylogenetic Polymorphisms Is Intimately Linked to Mitoribosomal Misreading. Publication Status: Online-Only",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_084239",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_084239"
                },
                {
                    "database": "PubMed",
                    "id": "35457201",
                    "url": "https://glygen.org/publication/PubMed/35457201"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q99N87",
                    "url": "https://www.uniprot.org/uniprot/Q99N87"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "gene": [
        {
            "name": "Mrps5",
            "url": "https://www.uniprot.org/uniprot/Q99N87",
            "locus": {
                "chromosome": "2",
                "start_pos": 127448749,
                "end_pos": 127429142,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSMUSG00000027374",
                        "url": "https://www.ensembl.org/id/ENSMUSG00000027374"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSMUSG00000027374",
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000027374",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "77721",
            "url": "https://www.ncbi.nlm.nih.gov/gene/77721",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR000851",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000851",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR005324",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR005324",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR013810",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013810",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR014721",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR014721",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR018192",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR018192",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR020568",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR020568",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "mmu:77721",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:77721",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "1924971",
            "url": "http://www.informatics.jax.org/marker/MGI:1924971",
            "database": "MGI",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "QNHTIYH",
            "url": "https://omabrowser.org/oma/group/QNHTIYH/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "5479674at2759",
            "url": "http://www.orthodb.org/?query=5479674at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR48277",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48277",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR48277:SF1",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48277:SF1",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "7PNT",
            "url": "https://www.rcsb.org/structure/7PNT",
            "database": "PDB",
            "categories": [
                "3D Structure"
            ]
        },
        {
            "id": "7PNU",
            "url": "https://www.rcsb.org/structure/7PNU",
            "database": "PDB",
            "categories": [
                "3D Structure"
            ]
        },
        {
            "id": "7PNV",
            "url": "https://www.rcsb.org/structure/7PNV",
            "database": "PDB",
            "categories": [
                "3D Structure"
            ]
        },
        {
            "id": "7PNW",
            "url": "https://www.rcsb.org/structure/7PNW",
            "database": "PDB",
            "categories": [
                "3D Structure"
            ]
        },
        {
            "id": "PF00333",
            "url": "http://pfam.xfam.org/family/PF00333",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF03719",
            "url": "http://pfam.xfam.org/family/PF03719",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_Q99N87",
            "url": "http://purl.obolibrary.org/obo/PR_Q99N87",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "R-MMU-5389840",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-5389840",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-MMU-5419276",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-5419276",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "NP_084239",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_084239",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "B2FDG7",
            "url": "https://www.uniprot.org/uniprot/B2FDG7",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "B2FDG7-1",
            "url": "https://www.uniprot.org/uniprot/B2FDG7-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q99N87",
            "url": "https://www.uniprot.org/uniprot/Q99N87",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q99N87-1",
            "url": "https://www.uniprot.org/uniprot/Q99N87-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MAAAVRAAGCLPALCSLQAGHFLSRQLSLNAFPVAATSFLAVKTALSHGSLSSRETRRNHCLTSLSHVLQTQCCVSSPGNWTGQQCRPYSFFTKLTAEELWKGALAETGAGARKGRGKRTKKKKRKDLNRGQIIGEGRSGFLWPGLNVPLIKSGVVQNIGQRSKEEQQKVEATMVEQREEWDRKRKIKVKRERGWSGNTWGGVSIGPPDPGPNGETYEDFDTRILEVRNVFNMTAKEGRKKSVRVLVAVGNGNGAAGFAIGKAADRGDAFRKAKNRAIHYLHYIERYEGHTIFHDISLRFKRTQIRMKKQPRGYGLRCHRAIITICRLIGIKDMYARVTGSMNMLNLTRGLFHGLARQETHQHLADKKGLHVVEFREECGPLPIVVASPHGALSKEPEPEPEVPDTKLDWQDVKAMQGLKRSVWFNLKRPAT",
        "length": 432,
        "header": "sp|Q99N87-1|RT05_MOUSE Isoform 1 of Small ribosomal subunit protein uS5m  OS=Mus musculus OX=10090 GN=Mrps5 PE=1 SV=1 CANONICAL=Q99N87-1"
    },
    "isoforms": [
        {
            "isoform_ac": "B2FDG7-1",
            "url": "",
            "sequence": {
                "sequence": "MEGPARTAGGAGHFLSRQLSLNAFPVAATSFLAVKTALSHGSLSSRETRRNHCLTSLSHVLQTQCCVSSPGNWTGQQCRPYSFFTKLTAEELWKGALAETGAGARKGRGKRTKKKKRKDLNRGQIIGEGRSGFLWPGLN",
                "length": 139,
                "header": "tr|B2FDG7-1|B2FDG7_MOUSE Computationally mapped isoform of Mitochondrial ribosomal protein S5  OS=Mus musculus OX=10090 GN=Mrps5 PE=1 SV=1 CANONICAL=Q99N87-1"
            },
            "locus": {
                "chromosome": "2",
                "start_pos": 127437615,
                "end_pos": 127432368,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000146131.2",
                        "url": "https://www.ensembl.org/id/ENSMUST00000146131.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000119674.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000119674.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q99N87-1",
            "url": "",
            "sequence": {
                "sequence": "MAAAVRAAGCLPALCSLQAGHFLSRQLSLNAFPVAATSFLAVKTALSHGSLSSRETRRNHCLTSLSHVLQTQCCVSSPGNWTGQQCRPYSFFTKLTAEELWKGALAETGAGARKGRGKRTKKKKRKDLNRGQIIGEGRSGFLWPGLNVPLIKSGVVQNIGQRSKEEQQKVEATMVEQREEWDRKRKIKVKRERGWSGNTWGGVSIGPPDPGPNGETYEDFDTRILEVRNVFNMTAKEGRKKSVRVLVAVGNGNGAAGFAIGKAADRGDAFRKAKNRAIHYLHYIERYEGHTIFHDISLRFKRTQIRMKKQPRGYGLRCHRAIITICRLIGIKDMYARVTGSMNMLNLTRGLFHGLARQETHQHLADKKGLHVVEFREECGPLPIVVASPHGALSKEPEPEPEVPDTKLDWQDVKAMQGLKRSVWFNLKRPAT",
                "length": 432,
                "header": "sp|Q99N87-1|RT05_MOUSE Isoform 1 of Small ribosomal subunit protein uS5m  OS=Mus musculus OX=10090 GN=Mrps5 PE=1 SV=1 CANONICAL=Q99N87-1"
            },
            "locus": {
                "chromosome": "2",
                "start_pos": 127445770,
                "end_pos": 127429348,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000028852",
                        "url": "https://www.ensembl.org/id/ENSMUST00000028852"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000028852",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000028852"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [
        {
            "title": "Proteomic analysis of the mammalian mitochondrial ribosome. Identification of protein components in the 28S small subunit.",
            "journal": "J. Biol. Chem.",
            "date": "2001",
            "authors": "Suzuki T., Watanabe K., Hanada T., Ueda T., Wada A., Takemoto-Hori C., Terasaki M.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q99N87",
                    "url": "https://www.uniprot.org/uniprot/Q99N87"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "11402041",
                    "url": "https://glygen.org/publication/PubMed/11402041"
                }
            ]
        },
        {
            "title": "Phenotype of Mrps5-Associated Phylogenetic Polymorphisms Is Intimately Linked to Mitoribosomal Misreading.",
            "journal": "International journal of molecular sciences",
            "date": "2022",
            "authors": "Juskeviciene R, Fritz AK, Brilkova M, Akbergenov R, Schmitt K, Rehrauer H, Laczko E, Isnard-Petit P, Thiam K, Eckert A, Schacht J, Wolfer DP, Bottger EC, Shcherbakov D",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_084239",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_084239"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "35457201",
                    "url": "https://glygen.org/publication/PubMed/35457201"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "mmu:77721",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:77721",
            "resource": "KEGG Pathway"
        },
        {
            "id": "R-MMU-5389840",
            "name": "Mitochondrial translation elongation",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-5389840",
            "resource": "Reactome",
            "description": "Mitochondrial translation elongation"
        },
        {
            "id": "R-MMU-5419276",
            "name": "Mitochondrial translation termination",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-5419276",
            "resource": "Reactome",
            "description": "Mitochondrial translation termination"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "D3ZYT2-1",
            "protein_name": "Mitochondrial ribosomal protein S5",
            "gene_name": "Mrps5",
            "tax_id": 10116,
            "organism": "Rattus norvegicus",
            "sequence": {
                "sequence": "MAAAVRAAGCLPALCSAPAGHFLSRQLSLNTFPVAATSFLAAKTAFSHGSLSPRETRHNHCLTSLSHALQTQCCISSPSNWTGQQYRPYSFFTKLTAEELWKGALAETGAGARKGRGKRTKKKKKKDLNKGQIIGEGRSGFLWPGLNVPLIKSGVVQNIGQRSKEEQQKVEADMAEQREEWDRKRKIKVKRERGWSGNTWGGVSIGPPDPGPNGETYEDFDTRILEVRNVFNMTAKEGRKKSVRVLVAVGNGNGAAGFAVGKAADRADAFRKAKNRAIHYLHYIERYEGHTIFHDISLRFKRTHIRMKKQPRGYGLRCHRAIITICRLIGIKDMYAKVNGSVNMLNLTRGLFHGLARQETHQHLADKKGLHVVEFREECGPLPIVVASPHGALSKEPEPEPEVPDTKLDWQDVKAMQGMKRSVWFNLKRSAT",
                "length": 432
            },
            "evidence": [
                {
                    "id": "45237317",
                    "url": "http://www.informatics.jax.org/homology/45237317",
                    "database": "MGI"
                }
            ],
            "common_name": "Rat"
        },
        {
            "uniprot_canonical_ac": "P82675-1",
            "protein_name": "Small ribosomal subunit protein uS5m",
            "gene_name": "MRPS5",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MATAVRAVGCLPVLCSGTAGHLLGRQCSLNTLPAASILAWKSVLGNGHLSSLGTRDTHPYASLSRALQTQCCISSPSHLMSQQYRPYSFFTKLTADELWKGALAETGAGAKKGRGKRTKKKKRKDLNRGQIIGEGRYGFLWPGLNVPLMKNGAVQTIAQRSKEEQEKVEADMIQQREEWDRKKKMKVKRERGWSGNSWGGISLGPPDPGPCGETYEDFDTRILEVRNVFTMTAKEGRKKSIRVLVAVGNGKGAAGFSIGKATDRMDAFRKAKNRAVHHLHYIERYEDHTIFHDISLRFKRTHIKMKKQPKGYGLRCHRAIITICRLIGIKDMYAKVSGSINMLSLTQGLFRGLSRQETHQQLADKKGLHVVEIREECGPLPIVVASPRGPLRKDPEPEDEVPDVKLDWEDVKTAQGMKRSVWSNLKRAAT",
                "length": 430
            },
            "evidence": [
                {
                    "id": "45237317",
                    "url": "http://www.informatics.jax.org/homology/45237317",
                    "database": "MGI"
                },
                {
                    "id": "Q99N87",
                    "url": "https://omabrowser.org/oma/group/Q99N87/",
                    "database": "OMA"
                }
            ],
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Molecular Function",
                "total": 2,
                "go_terms": [
                    {
                        "name": "RNA binding",
                        "id": "GO:0003723",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q99N87",
                                "url": "https://www.uniprot.org/uniprot/Q99N87"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "structural constituent of ribosome",
                        "id": "GO:0003735",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q99N87",
                                "url": "https://www.uniprot.org/uniprot/Q99N87"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 2,
                "go_terms": [
                    {
                        "name": "translation",
                        "id": "GO:0006412",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q99N87",
                                "url": "https://www.uniprot.org/uniprot/Q99N87"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "mitochondrial translation",
                        "id": "GO:0032543",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032543",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q99N87",
                                "url": "https://www.uniprot.org/uniprot/Q99N87"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 4,
                "go_terms": [
                    {
                        "name": "ribosome",
                        "id": "GO:0005840",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005840",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q99N87",
                                "url": "https://www.uniprot.org/uniprot/Q99N87"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "mitochondrial small ribosomal subunit",
                        "id": "GO:0005763",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005763",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q99N87",
                                "url": "https://www.uniprot.org/uniprot/Q99N87"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "mitochondrion",
                        "id": "GO:0005739",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q99N87",
                                "url": "https://www.uniprot.org/uniprot/Q99N87"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "mitochondrial inner membrane",
                        "id": "GO:0005743",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q99N87",
                                "url": "https://www.uniprot.org/uniprot/Q99N87"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 232,
            "end_pos": 234,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 346,
            "end_pos": 348,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 80,
            "end_pos": 82,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
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