{
    "uniprot_canonical_ac": "Q99MH6-1",
    "uniprot_ac": "Q99MH6",
    "uniprot_id": "NKD1_MOUSE",
    "mass": {
        "chemical_mass": 52391.0,
        "monoisotopic_mass": 52391.0
    },
    "refseq": {
        "ac": "NP_001157132",
        "name": "protein naked cuticle homolog 1 isoform 2",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157132"
    },
    "gene_names": [
        {
            "name": "Nkd1",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/Q99MH6",
            "id": "Q99MH6"
        },
        {
            "name": "2810434J10Rik; 9030215G15Rik; Nkd",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157132",
            "id": "NP_001157132"
        },
        {
            "name": "Nkd1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157132",
            "id": "NP_001157132"
        }
    ],
    "protein_names": [
        {
            "name": "Protein naked cuticle homolog 1",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "Q99MH6"
        },
        {
            "name": "Naked-1",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q99MH6"
        },
        {
            "name": "mNkd1",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q99MH6"
        },
        {
            "name": "mNkd",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q99MH6"
        },
        {
            "name": "protein naked cuticle homolog 1 isoform 1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_081556",
            "id": "NP_081556"
        },
        {
            "name": "protein naked cuticle homolog 1 isoform 2",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157132",
            "id": "NP_001157132"
        },
        {
            "name": "protein naked cuticle homolog 1; mNkd; mNkd1; naked-1; naked cuticle 1 homolog",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_081556",
            "id": "NP_081556"
        }
    ],
    "function": [
        {
            "annotation": "Cell autonomous antagonist of the canonical Wnt signaling pathway.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "E9Q5K6",
                    "url": "https://www.uniprot.org/uniprot/E9Q5K6#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "RU367060",
                    "url": "https://www.uniprot.org/uniprot/RU367060#function"
                }
            ]
        },
        {
            "annotation": "Cell autonomous antagonist of the canonical Wnt signaling pathway. May activate a second Wnt signaling pathway that controls planar cell polarity. Required for spermatogenesis.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q99MH6",
                    "url": "https://www.uniprot.org/uniprot/Q99MH6#function"
                },
                {
                    "database": "PubMed",
                    "id": "11274398",
                    "url": "https://glygen.org/publication/PubMed/11274398"
                },
                {
                    "database": "PubMed",
                    "id": "11356022",
                    "url": "https://glygen.org/publication/PubMed/11356022"
                },
                {
                    "database": "PubMed",
                    "id": "15546883",
                    "url": "https://glygen.org/publication/PubMed/15546883"
                }
            ]
        },
        {
            "annotation": "Deletion of the EF-hand from Nkd1 reduces the number of the elongating spermatids at haploid stage",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_081556",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_081556"
                },
                {
                    "database": "PubMed",
                    "id": "15546883",
                    "url": "https://glygen.org/publication/PubMed/15546883"
                },
                {
                    "database": "RefSeq",
                    "id": "NP_001157132",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157132"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [
        {
            "start_pos": 138,
            "end_pos": 163,
            "sequence_org": "WTFTLYDFDNNGKVTREDITSLLHTI",
            "sequence_mut": "",
            "comment": "Impairs inhibition of the Wnt signaling pathway.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q99MH6",
                    "url": "https://www.uniprot.org/uniprot/Q99MH6"
                },
                {
                    "database": "PubMed",
                    "id": "11274398",
                    "url": "https://glygen.org/publication/PubMed/11274398"
                }
            ]
        },
        {
            "start_pos": 144,
            "end_pos": 144,
            "sequence_org": "D",
            "sequence_mut": "V",
            "comment": "Impairs inhibition of the Wnt signaling pathway; when associated with V-146.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q99MH6",
                    "url": "https://www.uniprot.org/uniprot/Q99MH6"
                },
                {
                    "database": "PubMed",
                    "id": "11274398",
                    "url": "https://glygen.org/publication/PubMed/11274398"
                }
            ]
        },
        {
            "start_pos": 146,
            "end_pos": 146,
            "sequence_org": "D",
            "sequence_mut": "V",
            "comment": "Impairs inhibition of the Wnt signaling pathway; when associated with V-144.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q99MH6",
                    "url": "https://www.uniprot.org/uniprot/Q99MH6"
                },
                {
                    "database": "PubMed",
                    "id": "11274398",
                    "url": "https://glygen.org/publication/PubMed/11274398"
                }
            ]
        },
        {
            "start_pos": 149,
            "end_pos": 149,
            "sequence_org": "G",
            "sequence_mut": "W",
            "comment": "Impairs inhibition of the Wnt signaling pathway.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q99MH6",
                    "url": "https://www.uniprot.org/uniprot/Q99MH6"
                },
                {
                    "database": "PubMed",
                    "id": "11274398",
                    "url": "https://glygen.org/publication/PubMed/11274398"
                }
            ]
        }
    ],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q99MH6",
                    "url": "https://www.uniprot.org/uniprot/Q99MH6"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "gene": [
        {
            "name": "Nkd1",
            "url": "https://www.uniprot.org/uniprot/Q99MH6",
            "locus": {
                "chromosome": "8",
                "start_pos": 89321512,
                "end_pos": 89247982,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSMUSG00000031661",
                        "url": "https://www.ensembl.org/id/ENSMUSG00000031661"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSMUSG00000031661",
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000031661",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "93960",
            "url": "https://www.ncbi.nlm.nih.gov/gene/93960",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "Q99MH6",
            "url": "https://www.ebi.ac.uk/intact/interactors/id:Q99MH6*",
            "database": "IntAct",
            "categories": [
                "Other"
            ]
        },
        {
            "id": "IPR002048",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR011992",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR018247",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "mmu:93960",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:93960",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "2135954",
            "url": "http://www.informatics.jax.org/marker/MGI:2135954",
            "database": "MGI",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "SWERKQR",
            "url": "https://omabrowser.org/oma/group/SWERKQR/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "5398069at2759",
            "url": "http://www.orthodb.org/?query=5398069at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR22611",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22611",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR22611:SF2",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22611:SF2",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_Q99MH6",
            "url": "http://purl.obolibrary.org/obo/PR_Q99MH6",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "NP_081556",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_081556",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "E9Q5K6",
            "url": "https://www.uniprot.org/uniprot/E9Q5K6",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "E9Q5K6-1",
            "url": "https://www.uniprot.org/uniprot/E9Q5K6-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q99MH6",
            "url": "https://www.uniprot.org/uniprot/Q99MH6",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q99MH6-1",
            "url": "https://www.uniprot.org/uniprot/Q99MH6-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MGKLHSKPAAVCKRRESPEGDSFAVSAAWARKGIEEWIGRQRCPGSVSGPRQLRLAGTVGRGTRELVGDTSREALGEEDEDDFPLEVALPPEKIDSLGSGDEKRMERLSEPGQASKKQLKFEELQCDVSVEEDSRQEWTFTLYDFDNNGKVTREDITSLLHTIYEVVDSSVNHSPTSSKTLRVKLTVAPDGSQSKRSVLFNHTDLQSTRPRADTKPAEELRGWEKKQRAPLRFQGDSHLEQPDCYHHCVDENIERRNHYLDLAGIENYTSQFGPGSPSVAQKSELPPRISNPTRSRSHEPEAAHIPHRRPQGVDPGSFHLLDTPFAKASELQQRLRGTQDGSKHFVRSPKAQGKNMGMGHGARGARSKPPLVPTTHTVSPSAHLATSPALLPTLAPLGHKKHKHRAKESQASCRGLQGPLAAGGSTVMGREQVRELPAVVVYESQAGQAVQRHEHHHHHEHHHHYHHFYQP",
        "length": 471,
        "header": "sp|Q99MH6-1|NKD1_MOUSE Isoform 1 of Protein naked cuticle homolog 1  OS=Mus musculus OX=10090 GN=Nkd1 PE=1 SV=1 CANONICAL=Q99MH6-1"
    },
    "isoforms": [
        {
            "isoform_ac": "E9Q5K6-1",
            "url": "",
            "sequence": {
                "sequence": "MERLSEPGQASKKQLKFEELQCDVSVEEDSRQEWTFTLYDFDNNGKVTREDITSLLHTIYEVVDSSVNHSPTSSKTLRVKLTVAPDGSQSKRSVLFNHTDLQSTRPRADTKPAEELRGWEKKQRAPLRFQGDSHLEQPDCYHHCVDENIERRNHYLDLAGIENYTSQFGPGSPSVAQKSELPPRISNPTRSRSHEPEAAHIPHRRPQGVDPGSFHLLDTPFAKASELQQRLRGTQDGSKHFVRSPKAQGKNMGMGHGARGARSKPPLVPTTHTVSPSAHLATSPALLPTLAPLGHKKHKHRAKESQASCRGLQGPLAAGGSTVMGREQVRELPAVVVYESQAGQAVQRHEHHHHHEHHHHYHHFYQP",
                "length": 367,
                "header": "tr|E9Q5K6-1|NKD1_MOUSE Computationally mapped isoform of Protein naked cuticle homolog 1  OS=Mus musculus OX=10090 GN=Nkd1 PE=1 SV=1 CANONICAL=Q99MH6-1"
            },
            "locus": {
                "chromosome": "8",
                "start_pos": 89318777,
                "end_pos": 89309884,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000169179.3",
                        "url": "https://www.ensembl.org/id/ENSMUST00000169179.3"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000125935.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000125935.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q99MH6-1",
            "url": "",
            "sequence": {
                "sequence": "MGKLHSKPAAVCKRRESPEGDSFAVSAAWARKGIEEWIGRQRCPGSVSGPRQLRLAGTVGRGTRELVGDTSREALGEEDEDDFPLEVALPPEKIDSLGSGDEKRMERLSEPGQASKKQLKFEELQCDVSVEEDSRQEWTFTLYDFDNNGKVTREDITSLLHTIYEVVDSSVNHSPTSSKTLRVKLTVAPDGSQSKRSVLFNHTDLQSTRPRADTKPAEELRGWEKKQRAPLRFQGDSHLEQPDCYHHCVDENIERRNHYLDLAGIENYTSQFGPGSPSVAQKSELPPRISNPTRSRSHEPEAAHIPHRRPQGVDPGSFHLLDTPFAKASELQQRLRGTQDGSKHFVRSPKAQGKNMGMGHGARGARSKPPLVPTTHTVSPSAHLATSPALLPTLAPLGHKKHKHRAKESQASCRGLQGPLAAGGSTVMGREQVRELPAVVVYESQAGQAVQRHEHHHHHEHHHHYHHFYQP",
                "length": 471,
                "header": "sp|Q99MH6-1|NKD1_MOUSE Isoform 1 of Protein naked cuticle homolog 1  OS=Mus musculus OX=10090 GN=Nkd1 PE=1 SV=1 CANONICAL=Q99MH6-1"
            },
            "locus": {
                "chromosome": "8",
                "start_pos": 89318777,
                "end_pos": 89248135,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000034086",
                        "url": "https://www.ensembl.org/id/ENSMUST00000034086"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000034086",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000034086"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [
        {
            "title": "Cell autonomous regulation of multiple Dishevelled-dependent pathways by mammalian Nkd.",
            "journal": "Proc. Natl. Acad. Sci. U.S.A.",
            "date": "2001",
            "authors": "Yan D, Wallingford JB, Sun TQ, Nelson AM, Sakanaka C, Reinhard C, Harland RM, Fantl WJ, Williams LT",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q99MH6",
                    "url": "https://www.uniprot.org/uniprot/Q99MH6"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "11274398",
                    "url": "https://glygen.org/publication/PubMed/11274398"
                }
            ]
        },
        {
            "title": "Vertebrate proteins related to Drosophila Naked Cuticle bind Dishevelled and antagonize Wnt signaling.",
            "journal": "Dev. Biol.",
            "date": "2001",
            "authors": "Wharton KA Jr, Zimmermann G, Rousset R, Scott MP",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q99MH6",
                    "url": "https://www.uniprot.org/uniprot/Q99MH6"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "11356022",
                    "url": "https://glygen.org/publication/PubMed/11356022"
                }
            ]
        },
        {
            "title": "Mouse Nkd1, a Wnt antagonist, exhibits oscillatory gene expression in the PSM under the control of Notch signaling.",
            "journal": "Mech. Dev.",
            "date": "2004",
            "authors": "Ishikawa A, Kitajima S, Takahashi Y, Kokubo H, Kanno J, Inoue T, Saga Y",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q99MH6",
                    "url": "https://www.uniprot.org/uniprot/Q99MH6"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "15511637",
                    "url": "https://glygen.org/publication/PubMed/15511637"
                }
            ]
        },
        {
            "title": "A targeted mutation of Nkd1 impairs mouse spermatogenesis.",
            "journal": "J. Biol. Chem.",
            "date": "2005",
            "authors": "Li Q, Ishikawa TO, Miyoshi H, Oshima M, Taketo MM",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q99MH6",
                    "url": "https://www.uniprot.org/uniprot/Q99MH6"
                },
                {
                    "database": "RefSeq",
                    "id": "NP_001157132",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157132"
                },
                {
                    "database": "RefSeq",
                    "id": "NP_081556",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_081556"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "15546883",
                    "url": "https://glygen.org/publication/PubMed/15546883"
                }
            ]
        },
        {
            "title": "PR72, a novel regulator of Wnt signaling required for Naked cuticle function.",
            "journal": "Genes Dev.",
            "date": "2005",
            "authors": "Destree O., Bernards R., Hijmans E.M., Creyghton M.P., Eichhorn P.J.A., Maurer I., Roeel G.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q99MH6",
                    "url": "https://www.uniprot.org/uniprot/Q99MH6"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "15687260",
                    "url": "https://glygen.org/publication/PubMed/15687260"
                }
            ]
        },
        {
            "title": "Dominant-stable beta-catenin expression causes cell fate alterations and Wnt signaling antagonist expression in a murine granulosa cell tumor model.",
            "journal": "Cancer Res.",
            "date": "2006",
            "authors": "White L.D., Dalle S., Richards J.S., Boerboom D., Courty J.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q99MH6",
                    "url": "https://www.uniprot.org/uniprot/Q99MH6"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "16488995",
                    "url": "https://glygen.org/publication/PubMed/16488995"
                }
            ]
        },
        {
            "title": "Viable mice with compound mutations in the Wnt/Dvl pathway antagonists nkd1 and nkd2.",
            "journal": "Mol. Cell. Biol.",
            "date": "2007",
            "authors": "Zhang M., Zhang S., Ashfaq R., Castrillon D.H., Wharton K.A. Jr., Amanai M., Cagatay T., Kline J., Oez O.K.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q99MH6",
                    "url": "https://www.uniprot.org/uniprot/Q99MH6"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "17438140",
                    "url": "https://glygen.org/publication/PubMed/17438140"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "mmu:93960",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:93960",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "D4AAV5-1",
            "protein_name": "Protein naked cuticle homolog",
            "gene_name": "Nkd1",
            "tax_id": 10116,
            "organism": "Rattus norvegicus",
            "sequence": {
                "sequence": "MGKLHSKPAAVCKRRESPEGDSFAVSAAWARKGIEEWIGRQRCPGSVSGPRQLRLAGTVGRGARELVGDTSREALGEGDEDDFPLEVALPPEKTDSLVSGDEKRMEKLSEPGQASKKQLKFEELQCDVSVEEDSRQEWTFTLYDFDNNGKVTREDITSLLHTIYEVVDSSVNHSPTSSKTLRVKLTVAPDGSQSKRSVLFNHTDLQSARPRADTKPAEELRGWEKQQRAPLRFQGDSHLEQPDCYHHCVDENIERRNHYLDLAGIENYTSQFGPGSPSVAQKSELPPRISNPTRSRSHEPEAAHIPHRRPQGVDPGSFHLLDTPFVKASEPQQRLRGTQDGNKQFVRSPKAQGKNMGMGHVARGTRSKPPLVPTTHTVSPSAHLATGPALLPTLPPLGHKKHKHRAKESQASCRGLQAPLAAGGSTIMGREQVRELPAVVVYESQAGQSIQRHEHHHHHEHHHHYHHFYQP",
                "length": 471
            },
            "evidence": [
                {
                    "id": "45228244",
                    "url": "http://www.informatics.jax.org/homology/45228244",
                    "database": "MGI"
                }
            ],
            "common_name": "Rat"
        },
        {
            "uniprot_canonical_ac": "Q969G9-1",
            "protein_name": "Protein naked cuticle homolog 1",
            "gene_name": "NKD1",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MGKLHSKPAAVCKRRESPEGDSFAVSAAWARKGIEEWIGRQRCPGGVSGPRQLRLAGTIGRSTRELVGDVLRDTLSEEEEDDFRLEVALPPEKTDGLGSGDEKKMERVSEPCPGSKKQLKFEELQCDVSMEEDSRQEWTFTLYDFDNNGKVTREDITSLLHTIYEVVDSSVNHSPTSSKMLRVKLTVAPDGSQSKRSVLVNQADLQSARPRAETKPTEDLRSWEKKQRAPLRFQGDSRLEQSGCYHHCVDENIERRNHYLDLAGIENYTSQFGPGSPSVAQKSELPPRTSNPTRSRSHEPEAIHIPHRKPQGVDPASFHFLDTPIAKVSELQQRLRGTQDGSKHFVRSPKAQGKSVGVGHVARGARNKPPLGPAIPAVSPSAHLAASPALLPSLAPLGHKKHKHRAKESQQGCRGLQAPLASGGPVLGREHLRELPALVVYESQAGQPVQRHEHHHHHEHHHHYHHFYQT",
                "length": 470
            },
            "evidence": [
                {
                    "id": "45228244",
                    "url": "http://www.informatics.jax.org/homology/45228244",
                    "database": "MGI"
                },
                {
                    "id": "Q99MH6",
                    "url": "https://omabrowser.org/oma/group/Q99MH6/",
                    "database": "OMA"
                }
            ],
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Cellular Component",
                "total": 3,
                "go_terms": [
                    {
                        "name": "cytoplasm",
                        "id": "GO:0005737",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q99MH6",
                                "url": "https://www.uniprot.org/uniprot/Q99MH6"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "plasma membrane",
                        "id": "GO:0005886",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886",
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                            {
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                                "url": "https://www.uniprot.org/uniprot/Q99MH6"
                            }
                        ],
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                    },
                    {
                        "name": "protein phosphatase type 2A complex",
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                                "url": "https://www.uniprot.org/uniprot/Q99MH6"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 2,
                "go_terms": [
                    {
                        "name": "calcium ion binding",
                        "id": "GO:0005509",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509",
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                                "id": "Q99MH6",
                                "url": "https://www.uniprot.org/uniprot/Q99MH6"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "PDZ domain binding",
                        "id": "GO:0030165",
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                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q99MH6",
                                "url": "https://www.uniprot.org/uniprot/Q99MH6"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 9,
                "go_terms": [
                    {
                        "name": "Wnt signaling pathway",
                        "id": "GO:0016055",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q99MH6",
                                "url": "https://www.uniprot.org/uniprot/Q99MH6"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "negative regulation of Wnt signaling pathway",
                        "id": "GO:0030178",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030178",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q99MH6",
                                "url": "https://www.uniprot.org/uniprot/Q99MH6"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of non-canonical Wnt signaling pathway via JNK cascade",
                        "id": "GO:1901231",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901231",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q99MH6",
                                "url": "https://www.uniprot.org/uniprot/Q99MH6"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "negative regulation of convergent extension involved in axis elongation",
                        "id": "GO:1901233",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901233",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q99MH6",
                                "url": "https://www.uniprot.org/uniprot/Q99MH6"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "spermatogenesis",
                        "id": "GO:0007283",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q99MH6",
                                "url": "https://www.uniprot.org/uniprot/Q99MH6"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cell differentiation",
                        "id": "GO:0030154",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q99MH6",
                                "url": "https://www.uniprot.org/uniprot/Q99MH6"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "negative regulation of canonical Wnt signaling pathway",
                        "id": "GO:0090090",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q99MH6",
                                "url": "https://www.uniprot.org/uniprot/Q99MH6"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of Wnt signaling pathway, planar cell polarity pathway",
                        "id": "GO:2000096",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000096",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q99MH6",
                                "url": "https://www.uniprot.org/uniprot/Q99MH6"
                            }
                        ],
                        "pmid": ""
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                    {
                        "name": "positive regulation of protein catabolic process",
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                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q99MH6",
                                "url": "https://www.uniprot.org/uniprot/Q99MH6"
                            }
                        ],
                        "pmid": ""
                    }
                ]
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            "start_pos": 172,
            "end_pos": 174,
            "annotation": "n_glycosylation_sequon"
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    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        },
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        },
        {
            "name": "homologset.oma",
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