{ "uniprot_canonical_ac": "Q925N3-1", "uniprot_ac": "Q925N3", "uniprot_id": "PEX5R_RAT", "mass": { "chemical_mass": 66872.0, "monoisotopic_mass": 66872.0 }, "refseq": { "ac": "NP_775175", "name": "PEX5-related protein isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_775175" }, "gene_names": [ { "name": "Pex5l", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/Q925N3", "id": "Q925N3" }, { "name": "Pex2; TRIP8b; Trjip8b", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_775175", "id": "NP_775175" }, { "name": "Pex2", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q925N3", "id": "Q925N3" }, { "name": "Pex5l", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_775175", "id": "NP_775175" }, { "name": "Pex5r", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q925N3", "id": "Q925N3" }, { "name": "Trip8b", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q925N3", "id": "Q925N3" } ], "protein_names": [ { "name": "PEX5-related protein", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "Q925N3" }, { "name": "PEX5-like protein", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q925N3" }, { "name": "PEX5-related protein isoform 1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_775175", "id": "NP_775175" }, { "name": "PEX5-related protein; pex5Rp; PEX5-like protein; peroxin-5-related protein; peroxin 2; TPR-containing Rab8b-interacting protein; tetratricopeptide repeat-containing Rab8b-interacting protein", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_775175", "id": "NP_775175" }, { "name": "Peroxin-5-related protein", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q925N3" }, { "name": "Pex5Rp", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q925N3" }, { "name": "TPR-containing Rab8b-interacting protein", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q925N3" }, { "name": "TRIP8b", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q925N3" }, { "name": "Tetratricopeptide repeat-containing Rab8b-interacting protein", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q925N3" } ], "function": [ { "annotation": "A role of TRIP8b in receptor-mediated endocytosis.", "evidence": [ { "database": "RefSeq", "id": "NP_775175", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_775175" }, { "database": "PubMed", "id": "18620529", "url": "https://glygen.org/publication/PubMed/18620529" } ] }, { "annotation": "Accessory subunit of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels, regulating their cell-surface expression and cyclic nucleotide dependence.", "evidence": [ { "database": "UniProtKB", "id": "Q925N3", "url": "https://www.uniprot.org/uniprot/Q925N3#function" }, { "database": "PubMed", "id": "19555650", "url": "https://glygen.org/publication/PubMed/19555650" } ] }, { "annotation": "Hyperpolarization current expression was high in corticospinal neurons and low in corticostriatal and corticocortical neurons, a pattern mirrored by mRNA levels for HCN1 and Trip8b subunits.", "evidence": [ { "database": "RefSeq", "id": "NP_775175", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_775175" }, { "database": "PubMed", "id": "21795621", "url": "https://glygen.org/publication/PubMed/21795621" } ] }, { "annotation": "Loss of TRIP8b phosphorylation may affect HCN channel properties during epileptogenesis.", "evidence": [ { "database": "RefSeq", "id": "NP_775175", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_775175" }, { "database": "PubMed", "id": "31492750", "url": "https://glygen.org/publication/PubMed/31492750" } ] }, { "annotation": "Nedd4-2 plays an important role in the regulation of HCN1 trafficking and may compete with TRIP8b(1a-4) in this process", "evidence": [ { "database": "RefSeq", "id": "NP_775175", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_775175" }, { "database": "PubMed", "id": "24451387", "url": "https://glygen.org/publication/PubMed/24451387" } ] }, { "annotation": "TRIP8b isoforms are important regulators of HCN1 trafficking in entorhinal neurons.", "evidence": [ { "database": "RefSeq", "id": "NP_775175", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_775175" }, { "database": "PubMed", "id": "22363812", "url": "https://glygen.org/publication/PubMed/22363812" } ] } ], "disease": [ { "disease_id": "DOID:0080377", "recommended_name": { "id": "DOID:0080377", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0080377", "name": "peroxisomal biogenesis disorder", "description": "A peroxisomal biogenesis disorder that has_material_basis_in defects in PEX genes." }, "synonyms": [ { "id": "MONDO:0008953", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008953", "name": "peroxisome biogenesis disorder 1A (Zellweger)", "description": "" }, { "id": "MONDO:0008953", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008953", "name": "peroxisome biogenesis disorder 1A (Zellweger)", "description": "" }, { "id": "MONDO:0008953", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008953", "name": "Cerebrohepatorenal syndrome", "description": "" }, { "id": "MONDO:0008953", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008953", "name": "PBD1A", "description": "" }, { "id": "MONDO:0008953", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008953", "name": "Zs", "description": "" }, { "id": "MONDO:0008953", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008953", "name": "peroxisome biogenesis disorder, complementation group 1", "description": "" }, { "id": "MONDO:0008953", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008953", "name": "peroxisome biogenesis disorder, complementation group E", "description": "" }, { "id": "MIM:214100", "resource": "MIM", "url": "https://www.omim.org/entry/214100", "name": "Peroxisome biogenesis disorder 1A", "description": "Peroxisome biogenesis disorder 1A" } ], "evidence": [ { "id": "0080377", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:0080377" } ] }, { "disease_id": "DOID:0080477", "recommended_name": { "id": "DOID:0080477", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0080477", "name": "peroxisome biogenesis disorder 2A", "description": "A peroxisomal biogenesis disorder that has_material_basis_in homozygous mutation in the PEX5 gene on chromosome 12p13." }, "synonyms": [ { "id": "DOID:0080477", "resource": "Disease Ontology", "url": "http://disease-ontology.org/term/DOID:0080477", "name": "peroxisome biogenesis disorder 2A (Zellweger)", "description": "" }, { "id": "MONDO:0008954", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008954", "name": "peroxisome biogenesis disorder 2A (Zellweger)", "description": "" }, { "id": "MONDO:0008954", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008954", "name": "peroxisome biogenesis disorder 2A (Zellweger)", "description": "" }, { "id": "MONDO:0008954", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008954", "name": "PBD2A", "description": "" }, { "id": "MONDO:0008954", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008954", "name": "peroxisome biogenesis disorder, complementation group 2", "description": "" }, { "id": "MIM:214110", "resource": "MIM", "url": "https://www.omim.org/entry/214110", "name": "Peroxisome biogenesis disorder 2A", "description": "Peroxisome biogenesis disorder 2A" } ], "evidence": [ { "id": "0080477", "database": "Alliance of Genome Resources", "url": "https://www.alliancegenome.org/disease/DOID:0080477" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "Q925N3", "url": "https://www.uniprot.org/uniprot/Q925N3" } ], "common_name": "Rat" } ], "gene": [ { "name": "Pex5l", "url": "https://www.uniprot.org/uniprot/Q925N3", "locus": { "chromosome": "2", "start_pos": 115700972, "end_pos": 115913628, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSRNOG00000011211", "url": "https://www.ensembl.org/id/ENSRNOG00000011211" } ] } } ], "crossref": [ { "id": "ENSRNOG00000011211", "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000011211", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "286937", "url": "https://www.ncbi.nlm.nih.gov/gene/286937", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024111", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024111", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "rno:286937", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:286937", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ILQDPYD", "url": "https://omabrowser.org/oma/group/ILQDPYD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "2020042at2759", "url": "http://www.orthodb.org/?query=2020042at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10130", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10130", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10130:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10130:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13181", "url": "http://pfam.xfam.org/family/PF13181", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF13432", "url": "http://pfam.xfam.org/family/PF13432", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PR_Q925N3", "url": "http://purl.obolibrary.org/obo/PR_Q925N3", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_775175", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_775175", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "708407", "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=708407", "database": "RGD", "categories": [ "Organism-specific" ] }, { "id": "A0A8I6A617", "url": "https://www.uniprot.org/uniprot/A0A8I6A617", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I6A617-1", "url": "https://www.uniprot.org/uniprot/A0A8I6A617-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I6AGZ2", "url": "https://www.uniprot.org/uniprot/A0A8I6AGZ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I6AGZ2-1", "url": "https://www.uniprot.org/uniprot/A0A8I6AGZ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I6AHG5", "url": "https://www.uniprot.org/uniprot/A0A8I6AHG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I6AHG5-1", "url": "https://www.uniprot.org/uniprot/A0A8I6AHG5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I6AHT0", "url": "https://www.uniprot.org/uniprot/A0A8I6AHT0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I6AHT0-1", "url": "https://www.uniprot.org/uniprot/A0A8I6AHT0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I6AMT2", "url": "https://www.uniprot.org/uniprot/A0A8I6AMT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I6AMT2-1", "url": "https://www.uniprot.org/uniprot/A0A8I6AMT2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I6B1I9", "url": "https://www.uniprot.org/uniprot/A0A8I6B1I9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I6B1I9-1", "url": "https://www.uniprot.org/uniprot/A0A8I6B1I9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I6G884", "url": "https://www.uniprot.org/uniprot/A0A8I6G884", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I6G884-1", "url": "https://www.uniprot.org/uniprot/A0A8I6G884-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1LMT5", "url": "https://www.uniprot.org/uniprot/F1LMT5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1LMT5-1", "url": "https://www.uniprot.org/uniprot/F1LMT5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q925N3", "url": "https://www.uniprot.org/uniprot/Q925N3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q925N3-1", "url": "https://www.uniprot.org/uniprot/Q925N3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYQGHMQGKGSRAADKAVAMVMKEIPREESAEEKPLLTMTSQLVNEQQESRPLLSPSIDDFLCETKSEAIAKPVTSNTAVLTTGLDLLDLSEPVSQTQTKAKKSESSSKSSSLKKKADGSDLISADAEQRAQALRGPETSSLDLDIQTQLEKWDDVKFHGDRTSKGHLMAERKSCSSRAGSKELLWSSEHRSQPELSTGKSALNSESASELELVAPAQARLTKEHRWGSALLSRNHSLEEEFERAKAAVESDTEFWDKMQAEWEEMARRNWISENQEAQNQVTVSASEKGYYFHTENPFKDWPGAFEEGLKRLKEGDLPVTILFMEAAILQDPGNAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTSHQQDACEALKNWIKQNPKYKYLVKNKKGSPGLTRRMSKSPVDSSVLEGVKDLYLEAAHQNGDMIDPDLQTGLGVLFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEAVEAYTRALEIQPGFIRSRYNLGISCINLGAYREAVSNFLTALSLQRKSRNQQQVPHPAISGNIWAALRIALSLMDQPELFQAANLGDLDVLLRAFNLDP", "length": 602, "header": "sp|Q925N3-1|PEX5R_RAT Isoform 1 of PEX5-related protein OS=Rattus norvegicus OX=10116 GN=Pex5l PE=1 SV=1 CANONICAL=Q925N3-1" }, "isoforms": [ { "isoform_ac": "A0A8I6A617-1", "url": "", "sequence": { "sequence": "MSDSEMDGRTHIPSLLNALLSRNPVMQMNYLKSKEQGYGKLSSDEDLEIIVDQKQLVNEQQESRPLLSPSIDDFLCETKSEAIAKPVTSNTAVLTTGLDLLDLSEPVSQTQTKAKKSESSSKSSSLKKKADGSDLISADAEQRAQALRGPETSSLDLDIQTQLEKWDDVKFHGDRTSKGHLMAERKSCSSRAGSKELLWSSEHRSQPELSTGKSALNSESASELELVAPAQARLTKEHRWGSALLSRNHSLEEEFERAKAAVESDTEFWDKMQAEWEEMARRNWISENQEAQNQVTVSASEKGYYFHTENPFKDWPGAFEEGLKRLKEGDLPVTILFMEAAILQDPGDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTSHQQDACEALKNWIKQNPKYKYLVKNKKGSPGLTRRMSKSPVDSSVLEGVKDLYLEAAHQNGDMIDPDLQTGLGVLFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEAVEAYTRALEIQPGFIRSRYNLGISCINLGAYREAVSNFLTALSLQRKSRNQQQVPHPAISGNIWAALRIALSLMDQPELFQAANLGDLDVLLRAFNLDP", "length": 615, "header": "tr|A0A8I6A617-1|A0A8I6A617_RAT Computationally mapped isoform of Peroxisomal biogenesis factor 5-like OS=Rattus norvegicus OX=10116 GN=Pex5l PE=3 SV=1 CANONICAL=Q925N3-1" }, "locus": { "chromosome": "2", "start_pos": 115850319, "end_pos": 115701011, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000107964.1", "url": "https://www.ensembl.org/id/ENSRNOT00000107964.1" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000086465.1", "url": "https://www.ensembl.org/id/ENSRNOP00000086465.1" } ] } }, { "isoform_ac": "A0A8I6AGZ2-1", "url": "", "sequence": { "sequence": "MYQGHMQLVNEQQESRPLLSPSIDDFLCETKSEAIAKPVTSNTAVLTTGLDLLDLSEPVSQTQTKAKKSESSSKSSSLKKKADGSDLISADAEQRAQALRGPETSSLDLDIQTQLEKWDDVKFHGDRTSKGHLMAERKSCSSRAGSKELLWSSEHRSQPELSTGKSALNSESASELELVAPAQARLTKEHRWGSALLSRNHSLEEEFERAKAAVESDTEFWDKMQAEWEEMARRNWISENQEAQNQVTVSASEKGYYFHTENPFKDWPGAFEEGLKRLKEGDLPVTILFMEAAILQDPGDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTSHQQDACEALKNWIKQNPKYKYLVKNKKGSPGLTRRMSKSPVDSSVLEGVKDLYLEAAHQNGDMIDPDLQTGLGVLFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEAVEAYTRALEIQPGFIRSRYNLGISCINLGAYREAVSNFLTALSLQRKSRNQQQVPHPAISGNIWAALRIALSLMDQPELFQAANLGDLDVLLRAFNLDP", "length": 567, "header": "tr|A0A8I6AGZ2-1|A0A8I6AGZ2_RAT Computationally mapped isoform of Peroxisomal biogenesis factor 5-like OS=Rattus norvegicus OX=10116 GN=Pex5l PE=3 SV=1 CANONICAL=Q925N3-1" }, "locus": { "chromosome": "2", "start_pos": 115907982, "end_pos": 115701011, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000120122.1", "url": "https://www.ensembl.org/id/ENSRNOT00000120122.1" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000087652.1", "url": "https://www.ensembl.org/id/ENSRNOP00000087652.1" } ] } }, { "isoform_ac": "A0A8I6AHG5-1", "url": "", "sequence": { "sequence": "MYQGHMQKSKEQGYGKLSSDEDLEIIVDQKQVVGVTLKKKWHCLQKSDLTLALGKGSRAADKAVAMVMKEIPREESAEEKPLLTMTSQLVNEQQESRPLLSPSIDDFLCETKSEAIAKPVTSNTAVLTTGLDLLDLSEPVSQTQTKAKKSESSSKSSSLKKKADGSDLISADAEQRAQALRGPETSSLDLDIQTQLEKWDDVKFHGDRTSKGHLMAERKSCSSRAGSKELLWSSEHRSQPELSTGKSALNSESASELELVAPAQARLTKEHRWGSALLSRNHSLEEEFERAKAAVESDTEFWDKMQAEWEEMARRNWISENQEAQNQVTVSASEKGYYFHTENPFKDWPGAFEEGLKRLKEGDLPVTILFMEAAILQDPGDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTSHQQDACEALKNWIKQNPKYKYLVKNKKGSPGLTRRMSKSPVDSSVLEGVKDLYLEAAHQNGDMIDPDLQTGLGVLFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEAVEAYTRALEIQPGFIRSRYNLGISCINLGAYREAVSNFLTALSLQRKSRNQQQVPHPAISGNIWAALRIALSLMDQPELFQAANLGDLDVLLRAFNLDP", "length": 648, "header": "tr|A0A8I6AHG5-1|PEX5R_RAT Computationally mapped isoform of PEX5-related protein OS=Rattus norvegicus OX=10116 GN=Pex5l PE=1 SV=1 CANONICAL=Q925N3-1" }, "locus": { "chromosome": "2", "start_pos": 115907982, "end_pos": 115701011, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000105858.1", "url": "https://www.ensembl.org/id/ENSRNOT00000105858.1" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000092235.1", "url": "https://www.ensembl.org/id/ENSRNOP00000092235.1" } ] } }, { "isoform_ac": "A0A8I6AHT0-1", "url": "", "sequence": { "sequence": "MYQGHMQGKGSRAADKAVAMVMKEIPREESAEEKPLLTMTSQLVNEQQESRPLLSPSIDDFLCETKSEAIAKPVTSNTAVLTTGLDLLDLSEPVSQTQTKAKKSESSSKSSSLKKKADGSDLISADAEQRAQALRGPETSSLDLDIQTQLEKWDDVKFHGDRTSKGHLMAERKSCSSRAGSKELLWSSEHRSQPELSTGKSALNSESASELELVAPAQARLTKEHRWGSALLSRNHSLEEEFERAKAAVESDTEFWDKMQAEWEEMARRNWISENQEAQNQVTVSASEKGYYFHTENPFKDWPGAFEEGLKRLKEGDLPVTILFMEAAILQDPGDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTSHQQDACEALKNWIKQNPKYKYLVKNKKGSPGLTRRMSKSPVDSSVLEGVKDLYLEAAHQNGDMIDPDLQTGLGVLFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEAVEAYTRALEIQPGFIRSRYNLGISCINLGAYREAVSNFLTALSLQRKSRNQQQVPHPAISGNIWAALRIALSLMDQPELFQAANLGDLDVLLRAFNLDP", "length": 602, "header": "tr|A0A8I6AHT0-1|A0A8I6AHT0_RAT Computationally mapped isoform of Peroxisomal biogenesis factor 5-like OS=Rattus norvegicus OX=10116 GN=Pex5l PE=3 SV=1 CANONICAL=Q925N3-1" }, "locus": { "chromosome": "2", "start_pos": 115907982, "end_pos": 115701011, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000120297.1", "url": "https://www.ensembl.org/id/ENSRNOT00000120297.1" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000094453.1", "url": "https://www.ensembl.org/id/ENSRNOP00000094453.1" } ] } }, { "isoform_ac": "A0A8I6AMT2-1", "url": "", "sequence": { "sequence": "MQMNYLKSKEQGYGKLSSDEDLEIIVDQKQLVNEQQESRPLLSPSIDDFLCETKSEAIAKPVTSNTAVLTTGLDLLDLSEPVSQTQTKAKKSESSSKSSSLKKKADGSDLISADAEQRAQALRGPETSSLDLVDIQTQLEKWDDVKFHGDRTSKGHLMAERKSCSSRAGSKELLWSSEHRSQPELSTGKSALNSESASELELVAPAQARLTKEHRWGSALLSRNHSLEEEFERAKAAVESDTEFWDKMQAEWEEMARRNWISENQEAQNQVTVSASEKGYYFHTENPFKDWPGAFEEGLKRLKEGDLPVTILFMEAAILQDPGDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTSHQQDACEALKNWIKQNPKYKYLVKNKKGSPGLTRRMSKSPVDSSVLEGVKDLYLEAAHQNGDMIDPDLQTGLGVLFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEAVEAYTRALEIQPGFIRSRYNLGISCINLGAYREAVSNFLTALSLQRKSRNQQQVPHPAISGNIWAALRIALSLMDQPELFQAANLGDLDVLLRAFNLDP", "length": 591, "header": "tr|A0A8I6AMT2-1|A0A8I6AMT2_RAT Computationally mapped isoform of Peroxisomal biogenesis factor 5-like OS=Rattus norvegicus OX=10116 GN=Pex5l PE=3 SV=1 CANONICAL=Q925N3-1" }, "locus": { "chromosome": "2", "start_pos": 115850244, "end_pos": 115701011, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000098944.1", "url": "https://www.ensembl.org/id/ENSRNOT00000098944.1" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000095922.1", "url": "https://www.ensembl.org/id/ENSRNOP00000095922.1" } ] } }, { "isoform_ac": "A0A8I6B1I9-1", "url": "", "sequence": { "sequence": "MYQGHMQVVGVTLKKKWHCLQKSDLTLALGKGSRAADKAVAMVMKEIPREESAEEKPLLTMTSQLVNEQQESRPLLSPSIDDFLCETKSEAIAKPVTSNTAVLTTGLDLLDLSEPVSQTQTKAKKSESSSKSSSLKKKADGSDLISADAEQRAQALRGPETSSLDLDIQTQLEKWDDVKFHGDRTSKGHLMAERKSCSSRAGSKELLWSSEHRSQPELSTGKSALNSESASELELVAPAQARLTKEHRWGSALLSRNHSLEEEFERAKAAVESDTEFWDKMQAEWEEMARRNWISENQEAQNQVTVSASEKGYYFHTENPFKDWPGAFEEGLKRLKEGDLPVTILFMEAAILQDPGDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTSHQQDACEALKNWIKQNPKYKYLVKNKKGSPGLTRRMSKSPVDSSVLEGVKDLYLEAAHQNGDMIDPDLQTGLGVLFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEAVEAYTRALEIQPGFIRSRYNLGISCINLGAYREAVSNFLTALSLQRKSRNQQQVPHPAISGNIWAALRIALSLMDQPELFQAANLGDLDVLLRAFNLDP", "length": 624, "header": "tr|A0A8I6B1I9-1|PEX5R_RAT Computationally mapped isoform of PEX5-related protein OS=Rattus norvegicus OX=10116 GN=Pex5l PE=1 SV=1 CANONICAL=Q925N3-1" }, "locus": { "chromosome": "2", "start_pos": 115907982, "end_pos": 115701011, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000113164.1", "url": "https://www.ensembl.org/id/ENSRNOT00000113164.1" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000094803.1", "url": "https://www.ensembl.org/id/ENSRNOP00000094803.1" } ] } }, { "isoform_ac": "A0A8I6G884-1", "url": "", "sequence": { "sequence": "MSDSEMDGRTHIPSLLNALLSRNPVMQMNYLKSKEQGYGKLSSDEDLEIIVDQKQGKGSRAADKAVAMVMKEIPREESAEEKPLLTMTSQLVNEQQESRPLLSPSIDDFLCETKSEAIAKPVTSNTAVLTTGLDLLDLSEPVSQTQTKAKKSESSSKSSSLKKKADGSDLISADAEQRAQALRGPETSSLDLDIQTQLEKWDDVKFHGDRTSKGHLMAERKSCSSRAGSKELLWSSEHRSQPELSTGKSALNSESASELELVAPAQARLTKEHRWGSALLSRNHSLEEEFERAKAAVESDTEFWDKMQAEWEEMARRNWISENQEAQNQVTVSASEKGYYFHTENPFKDWPGAFEEGLKRLKEGDLPVTILFMEAAILQDPGDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTSHQQDACEALKNWIKQNPKYKYLVKNKKGSPGLTRRMSKSPVDSSVLEGVKDLYLEAAHQNGDMIDPDLQTGLGVLFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEAVEAYTRALEIQPGFIRSRYNLGISCINLGAYREAVSNFLTALSLQRKSRNQQQVPHPAISGNIWAALRIALSLMDQPELFQAANLGDLDVLLRAFNLDP", "length": 650, "header": "tr|A0A8I6G884-1|A0A8I6G884_RAT Computationally mapped isoform of Peroxisomal biogenesis factor 5-like OS=Rattus norvegicus OX=10116 GN=Pex5l PE=3 SV=1 CANONICAL=Q925N3-1" }, "locus": { "chromosome": "2", "start_pos": 115850319, "end_pos": 115701011, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000097356.1", "url": "https://www.ensembl.org/id/ENSRNOT00000097356.1" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000082985.1", "url": "https://www.ensembl.org/id/ENSRNOP00000082985.1" } ] } }, { "isoform_ac": "F1LMT5-1", "url": "", "sequence": { "sequence": "IYKGIFIDTLRNSLKHETSKTTKAADKAVAMVMKEIPREESAEEKPLLTMTSQLVNEQQESRPLLSPSIDDFLCETKSEAIAKPVTSNTAVLTTGLDLLDLSEPVSQTQTKAKKSESSSKSSSLKKKADGSDLISADAEQRAQALRGPETSSLDLDIQTQLEKWDDVKFHGDRTSKGHLMAERKSCSSRAGSKELLWSSEHRSQPELSTGKSALNSESASELELVAPAQARLTKEHRWGSALLSRNHSLEEEFERAKAAVESDTEFWDKMQAEWEEMARRNWISENQEAQNQVTVSASEKGYYFHTENPFKDWPGAFEEGLKRLKEGDLPVTILFMEAAILQDPGDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTSHQQDACEALKNWIKQNPKYKYLVKNKKGSPGLTRRMSKSPVDSSVLEGVKDLYLEAAHQNGDMIDPDLQTGLGVLFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEAVEAYTRALEIQPGFIRSRYNLGISCINLGAYREAVSNFLTALSLQRKSRNQQQVPHPAISGNIWAALRIALSLMDQPELFQAANLGDLDVLLRAFNLDP", "length": 613, "header": "tr|F1LMT5-1|F1LMT5_RAT Computationally mapped isoform of Peroxisomal biogenesis factor 5-like OS=Rattus norvegicus OX=10116 GN=Pex5l PE=1 SV=3 CANONICAL=Q925N3-1" }, "locus": { "chromosome": "2", "start_pos": 115774858, "end_pos": 115701011, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000015200.5", "url": "https://www.ensembl.org/id/ENSRNOT00000015200.5" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000015200.4", "url": "https://www.ensembl.org/id/ENSRNOP00000015200.4" } ] } }, { "isoform_ac": "Q925N3-1", "url": "", "sequence": { "sequence": "MYQGHMQGKGSRAADKAVAMVMKEIPREESAEEKPLLTMTSQLVNEQQESRPLLSPSIDDFLCETKSEAIAKPVTSNTAVLTTGLDLLDLSEPVSQTQTKAKKSESSSKSSSLKKKADGSDLISADAEQRAQALRGPETSSLDLDIQTQLEKWDDVKFHGDRTSKGHLMAERKSCSSRAGSKELLWSSEHRSQPELSTGKSALNSESASELELVAPAQARLTKEHRWGSALLSRNHSLEEEFERAKAAVESDTEFWDKMQAEWEEMARRNWISENQEAQNQVTVSASEKGYYFHTENPFKDWPGAFEEGLKRLKEGDLPVTILFMEAAILQDPGNAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTSHQQDACEALKNWIKQNPKYKYLVKNKKGSPGLTRRMSKSPVDSSVLEGVKDLYLEAAHQNGDMIDPDLQTGLGVLFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEAVEAYTRALEIQPGFIRSRYNLGISCINLGAYREAVSNFLTALSLQRKSRNQQQVPHPAISGNIWAALRIALSLMDQPELFQAANLGDLDVLLRAFNLDP", "length": 602, "header": "sp|Q925N3-1|PEX5R_RAT Isoform 1 of PEX5-related protein OS=Rattus norvegicus OX=10116 GN=Pex5l PE=1 SV=1 CANONICAL=Q925N3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [ { "start_pos": 181, "end_pos": 181, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q925N3", "url": "https://www.uniprot.org/uniprot/Q925N3" } ], "site_lbl": "Ser181" }, { "start_pos": 229, "end_pos": 229, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q925N3", "url": "https://www.uniprot.org/uniprot/Q925N3" }, { "database": "PubMed", "id": "22673903", "url": "https://glygen.org/publication/PubMed/22673903" }, { "database": "iPTMnet", "id": "Q925N3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q925N3" } ], "site_lbl": "Ser229" }, { "start_pos": 233, "end_pos": 233, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q925N3", "url": "https://www.uniprot.org/uniprot/Q925N3" }, { "database": "PubMed", "id": "22673903", "url": "https://glygen.org/publication/PubMed/22673903" }, { "database": "iPTMnet", "id": "Q925N3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q925N3" } ], "site_lbl": "Ser233" }, { "start_pos": 237, "end_pos": 237, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q925N3", "url": "https://www.uniprot.org/uniprot/Q925N3" }, { "database": "PubMed", "id": "22673903", "url": "https://glygen.org/publication/PubMed/22673903" }, { "database": "iPTMnet", "id": "Q925N3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q925N3" } ], "site_lbl": "Ser237" }, { "start_pos": 421, "end_pos": 421, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q925N3", "url": "https://www.uniprot.org/uniprot/Q925N3" } ], "site_lbl": "Ser421" }, { "start_pos": 423, "end_pos": 423, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q925N3", "url": "https://www.uniprot.org/uniprot/Q925N3" }, { "database": "PubMed", "id": "22673903", "url": "https://glygen.org/publication/PubMed/22673903" }, { "database": "iPTMnet", "id": "Q925N3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q925N3" } ], "site_lbl": "Ser423" } ], "glycation": [], "keywords": [], "publication": [ { "title": "Rab8b and its interacting partner TRIP8b are involved in regulated secretion in AtT20 cells.", "journal": "J. Biol. Chem.", "date": "2001", "authors": "Chen S., Liang M.C., Ngsee J.K., Chia J.N., Ting A.E.", "evidence": [ { "database": "UniProtKB", "id": "Q925N3", "url": "https://www.uniprot.org/uniprot/Q925N3" } ], "reference": [ { "type": "PubMed", "id": "11278749", "url": "https://glygen.org/publication/PubMed/11278749" } ] }, { "title": "Analysis of proteins interacting with TRIP8b adapter.", "journal": "Biochemistry. Biokhimiia", "date": "2008", "authors": "Popova NV, Plotnikov AN, Ziganshin RKh, Deyev IE, Petrenko AG", "evidence": [ { "database": "RefSeq", "id": "NP_775175", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_775175" } ], "reference": [ { "type": "PubMed", "id": "18620529", "url": "https://glygen.org/publication/PubMed/18620529" } ] }, { "title": "Association with the auxiliary subunit PEX5R/Trip8b controls responsiveness of HCN channels to cAMP and adrenergic stimulation.", "journal": "Neuron", "date": "2009", "authors": "Hofmann A., Roeper J., Wenzel D., Pfeifer A., Vlachos A., Fakler B., Schulte U., Bildl W., Zolles G., Deller T., Klocker N., Muller C.S., Fleischmann B.K., Thumfart J.O.", "evidence": [ { "database": "UniProtKB", "id": "Q925N3", "url": "https://www.uniprot.org/uniprot/Q925N3" } ], "reference": [ { "type": "PubMed", "id": "19555650", "url": "https://glygen.org/publication/PubMed/19555650" } ] }, { "title": "Corticospinal-specific HCN expression in mouse motor cortex: I(h)-dependent synaptic integration as a candidate microcircuit mechanism involved in motor control.", "journal": "Journal of neurophysiology", "date": "2011", "authors": "Sheets PL, Suter BA, Kiritani T, Chan CS, Surmeier DJ, Shepherd GM", "evidence": [ { "database": "RefSeq", "id": "NP_775175", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_775175" } ], "reference": [ { "type": "PubMed", "id": "21795621", "url": "https://glygen.org/publication/PubMed/21795621" } ] }, { "title": "Regulation of axonal HCN1 trafficking in perforant path involves expression of specific TRIP8b isoforms.", "journal": "PloS one", "date": "2012", "authors": "Wilkars W, Liu Z, Lewis AS, Stoub TR, Ramos EM, Brandt N, Nicholson DA, Chetkovich DM, Bender RA", "evidence": [ { "database": "RefSeq", "id": "NP_775175", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_775175" } ], "reference": [ { "type": "PubMed", "id": "22363812", "url": "https://glygen.org/publication/PubMed/22363812" } ] }, { "title": "Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.", "journal": "Nature communications", "date": "2012", "authors": "Lundby A, Secher A, Lage K, Nordsborg NB, Dmytriyev A, Lundby C, Olsen JV", "evidence": [ { "database": "UniProtKB", "id": "Q925N3", "url": "https://www.uniprot.org/uniprot/Q925N3" }, { "database": "UniProtKB", "id": "F1LMT5", "url": "https://www.uniprot.org/uniprot/F1LMT5" }, { "database": "iPTMnet", "id": "Q925N3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q925N3" } ], "reference": [ { "type": "PubMed", "id": "22673903", "url": "https://glygen.org/publication/PubMed/22673903" } ] }, { "title": "Nedd4-2 regulates surface expression and may affect N-glycosylation of hyperpolarization-activated cyclic nucleotide-gated (HCN)-1 channels.", "journal": "FASEB journal : official publication of the Federation of American Societies for Experimental Biology", "date": "2014", "authors": "Wilkars W, Wollberg J, Mohr E, Han M, Chetkovich DM, Bahring R, Bender RA", "evidence": [ { "database": "RefSeq", "id": "NP_775175", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_775175" } ], "reference": [ { "type": "PubMed", "id": "24451387", "url": "https://glygen.org/publication/PubMed/24451387" } ] }, { "title": "Phosphorylation of the HCN channel auxiliary subunit TRIP8b is altered in an animal model of temporal lobe epilepsy and modulates channel function.", "journal": "The Journal of biological chemistry", "date": "2019", "authors": "Foote KM, Lyman KA, Han Y, Michailidis IE, Heuermann RJ, Mandikian D, Trimmer JS, Swanson GT, Chetkovich DM", "evidence": [ { "database": "RefSeq", "id": "NP_775175", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_775175" } ], "reference": [ { "type": "PubMed", "id": "31492750", "url": "https://glygen.org/publication/PubMed/31492750" } ] } ], "pathway": [ { "id": "rno:286937", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:286937", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q8C437-1", "protein_name": "PEX5-related protein", "gene_name": "Pex5l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MYQGHMQLVNEQQESRPLLSPSIDDFLCETKSEAIAKPVTSNTAVLTTGLDLLDLSEPVSQPQTKAKKSEPSSKSSSLKKKADGSDLISADAEQRAQALRGPETSSLDLDIQTQLEKWDDVKFHGDRTSKGHLMAERKSCSSRTGSKELLWSAEHRSQPELSTGKSALNSESASELELVAPAQARLTKEHRWGSALLSRNHSLEEEFERAKAAVESDTEFWDKMQAEWEEMARRNWISENQEAQNQVTVSASEKGYYFHTENPFKDWPGAFEEGLKRLKEGDLPVTILFMEAAILQDPGDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTSHQQDACEALKNWIKQNPKYKYLVKNKKGSPGLTRRMSKSPVDSSVLEGVKELYLEAAHQNGDMIDPDLQTGLGVLFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEAVEAYTRALEIQPGFIRSRYNLGISCINLGAYREAVSNFLTALSLQRKSRNQQQVPHPAISGNIWAALRIALSLMDQPELFQAANLGDLDVLLRAFNLDP", "length": 567 }, "evidence": [ { "id": "45231405", "url": "http://www.informatics.jax.org/homology/45231405", "database": "MGI" } ], "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IYB4-1", "protein_name": "PEX5-related protein", "gene_name": "PEX5L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MYQGHMQKSKEQGYGKLSSDEDLEIIVDQKQGKGSRAADKAVAMVMKEIPREESAEEKPLLTMTSQLVNEQQESRPLLSPSIDDFLCETKSEAIARPVTSNTAVLTTGLDLLDLSEPVSQTQTKAKKSEPSSKTSSLKKKADGSDLISTDAEQRGQPLRVPETSSLDLDIQTQLEKWDDVKFHGDRNTKGHPMAERKSSSSRTGSKELLWSSEHRSQPELSGGKSALNSESASELELVAPTQARLTKEHRWGSALLSRNHSLEEEFERAKAAVESDTEFWDKMQAEWEEMARRNWISENQEAQNQVTISASEKGYYFHTENPFKDWPGAFEEGLKRLKEGDLPVTILFMEAAILQDPGDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTGHQQDACDALKNWIKQNPKYKYLVKSKKGSPGLTRRMSKSPVDSSVLEGVKELYLEAAHQNGDMIDPDLQTGLGVLFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEAVEAYTRALEIQPGFIRSRYNLGISCINLGAYREAVSNFLTALSLQRKSRNQQQVPHPAISGNIWAALRIALSLMDQPELFQAANLGDLDVLLRAFNLDP", "length": 626 }, "evidence": [ { "id": "45231405", "url": "http://www.informatics.jax.org/homology/45231405", "database": "MGI" } ], "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 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"https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "Q925N3", "url": "https://www.uniprot.org/uniprot/Q925N3" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "Q925N3", "url": "https://www.uniprot.org/uniprot/Q925N3" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "Q925N3", "url": "https://www.uniprot.org/uniprot/Q925N3" } ], "pmid": "" }, { "name": "intracellular cyclic nucleotide activated cation channel complex", "id": "GO:0017071", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017071", "evidence": [ { "database": "UniProtKB", "id": "Q925N3", "url": "https://www.uniprot.org/uniprot/Q925N3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": 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