{
    "uniprot_canonical_ac": "Q923A2-1",
    "uniprot_ac": "Q923A2",
    "uniprot_id": "SPDLY_MOUSE",
    "mass": {
        "chemical_mass": 70237.0,
        "monoisotopic_mass": 70237.0
    },
    "refseq": {
        "ac": "NP_081687",
        "name": "protein Spindly",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_081687"
    },
    "gene_names": [
        {
            "name": "Spdl1",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/Q923A2",
            "id": "Q923A2"
        },
        {
            "name": "1700018I02Rik; 2600001J17Rik; 2810049B11Rik; Ccdc99",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_081687",
            "id": "NP_081687"
        },
        {
            "name": "Ccdc99",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/Q923A2",
            "id": "Q923A2"
        },
        {
            "name": "Spdl1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_081687",
            "id": "NP_081687"
        }
    ],
    "protein_names": [
        {
            "name": "Protein Spindly",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "Q923A2"
        },
        {
            "name": "Coiled-coil domain-containing protein 99",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q923A2"
        },
        {
            "name": "Spindle apparatus coiled-coil domain-containing protein 1",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q923A2"
        },
        {
            "name": "coiled-coil domain-containing protein 99; coiled-coil domain containing 99; spindle apparatus coiled-coil domain-containing protein 1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_081687",
            "id": "NP_081687"
        },
        {
            "name": "protein Spindly",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_081687",
            "id": "NP_081687"
        }
    ],
    "function": [
        {
            "annotation": "Overexpression of mSpindly failed to enhance inactivation of SAC and acceleration of the meiotic process.",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_081687",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_081687"
                },
                {
                    "database": "PubMed",
                    "id": "20505367",
                    "url": "https://glygen.org/publication/PubMed/20505367"
                }
            ]
        },
        {
            "annotation": "Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track) (By similarity). Plays a role in cell migration (By similarity).",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q923A2",
                    "url": "https://www.uniprot.org/uniprot/Q923A2#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "MF_03041",
                    "url": "https://www.uniprot.org/uniprot/MF_03041#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "Q96EA4",
                    "url": "https://www.uniprot.org/uniprot/Q96EA4#function"
                }
            ]
        },
        {
            "annotation": "Spdl1 expression is significantly down-regulated in Mrtfb knockout mouse intestine.",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_081687",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_081687"
                },
                {
                    "database": "PubMed",
                    "id": "31690663",
                    "url": "https://glygen.org/publication/PubMed/31690663"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q923A2",
                    "url": "https://www.uniprot.org/uniprot/Q923A2"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "gene": [
        {
            "name": "Spdl1",
            "url": "https://www.uniprot.org/uniprot/Q923A2",
            "locus": {
                "chromosome": "11",
                "start_pos": 34700017,
                "end_pos": 34724468,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSMUSG00000069910",
                        "url": "https://www.ensembl.org/id/ENSMUSG00000069910"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSMUSG00000069910",
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000069910",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "70385",
            "url": "https://www.ncbi.nlm.nih.gov/gene/70385",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR028593",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR028593",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "mmu:70385",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:70385",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "1917635",
            "url": "http://www.informatics.jax.org/marker/MGI:1917635",
            "database": "MGI",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "KQHAFTK",
            "url": "https://omabrowser.org/oma/group/KQHAFTK/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "3109335at2759",
            "url": "http://www.orthodb.org/?query=3109335at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR32123",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32123",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR32123:SF9",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32123:SF9",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_Q923A2",
            "url": "http://purl.obolibrary.org/obo/PR_Q923A2",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "R-MMU-141430",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-141430",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-MMU-141444",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-141444",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-MMU-2467813",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-2467813",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-MMU-2500257",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-2500257",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-MMU-5663220",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-5663220",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-MMU-68877",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-68877",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-MMU-9648025",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9648025",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "NP_081687",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_081687",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q923A2",
            "url": "https://www.uniprot.org/uniprot/Q923A2",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q923A2-1",
            "url": "https://www.uniprot.org/uniprot/Q923A2-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MEADITNLRNKLKECEDERLKAAHYGLQLLERQTELQSQLDKCHEEMMITAEKYNQEKHALQREVELKSRMLDSLSCECEALKQQQKAQLEQLEVQLHRSHRQEVSDLKNKLENLKVELDEARLGEKQLKQKLDLQGELLAHKSEELRLLSEQRVLSSMSSELLALETELTAAEGVKNALKEEVNELQYKQEQLECLNTSLLHQVDRLKEEKEEREREAVSYYNALEKARVENQDLQVQLGHALQQAADPNSKGNSLFAEVEDRRVAMERQLNLMKDKYQSLKKQNAFTRDQMNKMKLQISTLLRMRGSQTEFEQQERLFAMIEQKNGEIKHLLGEINKLEKFKNLYESMESRPSTSDTACVLEDSTYYSDLLQLKLDKLNKENESTKDELSIQRMKALFESQRALDIERKLFTNERHLQLSESENMKLRAKLDELKLKYEPEERIEVPVLKRRREVLPLNITTPEETEETAAASATEDGVSRLPPHREEESCLNSLKDNTVQWKQPASSCVQPASLSPHKNLHLDTQPKKEKKCVKLVDSPANIEVLHEQSGNTPNSPRLTAESKLPTEVKERIETTSKLGKGACKKSHNIIYVSSKSAPETQCSQQ",
        "length": 608,
        "header": "sp|Q923A2-1|SPDLY_MOUSE Isoform 1 of Protein Spindly  OS=Mus musculus OX=10090 GN=Spdl1 PE=1 SV=2 CANONICAL=Q923A2-1"
    },
    "isoforms": [
        {
            "isoform_ac": "Q923A2-1",
            "url": "",
            "sequence": {
                "sequence": "MEADITNLRNKLKECEDERLKAAHYGLQLLERQTELQSQLDKCHEEMMITAEKYNQEKHALQREVELKSRMLDSLSCECEALKQQQKAQLEQLEVQLHRSHRQEVSDLKNKLENLKVELDEARLGEKQLKQKLDLQGELLAHKSEELRLLSEQRVLSSMSSELLALETELTAAEGVKNALKEEVNELQYKQEQLECLNTSLLHQVDRLKEEKEEREREAVSYYNALEKARVENQDLQVQLGHALQQAADPNSKGNSLFAEVEDRRVAMERQLNLMKDKYQSLKKQNAFTRDQMNKMKLQISTLLRMRGSQTEFEQQERLFAMIEQKNGEIKHLLGEINKLEKFKNLYESMESRPSTSDTACVLEDSTYYSDLLQLKLDKLNKENESTKDELSIQRMKALFESQRALDIERKLFTNERHLQLSESENMKLRAKLDELKLKYEPEERIEVPVLKRRREVLPLNITTPEETEETAAASATEDGVSRLPPHREEESCLNSLKDNTVQWKQPASSCVQPASLSPHKNLHLDTQPKKEKKCVKLVDSPANIEVLHEQSGNTPNSPRLTAESKLPTEVKERIETTSKLGKGACKKSHNIIYVSSKSAPETQCSQQ",
                "length": 608,
                "header": "sp|Q923A2-1|SPDLY_MOUSE Isoform 1 of Protein Spindly  OS=Mus musculus OX=10090 GN=Spdl1 PE=1 SV=2 CANONICAL=Q923A2-1"
            },
            "locus": {
                "chromosome": "11",
                "start_pos": 34721707,
                "end_pos": 34700525,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000093191",
                        "url": "https://www.ensembl.org/id/ENSMUST00000093191"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000090882",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000090882"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [
        {
            "start_pos": 279,
            "end_pos": 279,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Tyr",
            "comment": "",
            "evidence": [
                {
                    "database": "phospho.ELM",
                    "id": "Q923A2",
                    "url": "http://phospho.elm.eu.org/byAccession/Q923A2.html"
                },
                {
                    "database": "iPTMnet",
                    "id": "Q923A2",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q923A2"
                },
                {
                    "database": "PubMed",
                    "id": "17203969",
                    "url": "https://glygen.org/publication/PubMed/17203969"
                }
            ],
            "site_lbl": "Tyr279"
        },
        {
            "start_pos": 281,
            "end_pos": 281,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Ser",
            "comment": "",
            "evidence": [
                {
                    "database": "phospho.ELM",
                    "id": "Q923A2",
                    "url": "http://phospho.elm.eu.org/byAccession/Q923A2.html"
                },
                {
                    "database": "iPTMnet",
                    "id": "Q923A2",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q923A2"
                },
                {
                    "database": "PubMed",
                    "id": "19144319",
                    "url": "https://glygen.org/publication/PubMed/19144319"
                }
            ],
            "site_lbl": "Ser281"
        },
        {
            "start_pos": 516,
            "end_pos": 516,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Ser",
            "comment": "Phosphoserine",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q923A2",
                    "url": "https://www.uniprot.org/uniprot/Q923A2"
                }
            ],
            "site_lbl": "Ser516"
        },
        {
            "start_pos": 518,
            "end_pos": 518,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Ser",
            "comment": "Phosphoserine",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q923A2",
                    "url": "https://www.uniprot.org/uniprot/Q923A2"
                }
            ],
            "site_lbl": "Ser518"
        },
        {
            "start_pos": 558,
            "end_pos": 558,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Ser",
            "comment": "Phosphoserine",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q923A2",
                    "url": "https://www.uniprot.org/uniprot/Q923A2"
                },
                {
                    "database": "PubMed",
                    "id": "21183079",
                    "url": "https://glygen.org/publication/PubMed/21183079"
                },
                {
                    "database": "iPTMnet",
                    "id": "Q923A2",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q923A2"
                }
            ],
            "site_lbl": "Ser558"
        }
    ],
    "glycation": [],
    "keywords": [],
    "publication": [
        {
            "title": "Protein phosphorylation and expression profiling by Yin-yang multidimensional liquid chromatography (Yin-yang MDLC) mass spectrometry.",
            "journal": "Journal of proteome research",
            "date": "2007",
            "authors": "Dai J, Jin WH, Sheng QH, Shieh CH, Wu JR, Zeng R",
            "evidence": [
                {
                    "database": "iPTMnet",
                    "id": "Q923A2",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q923A2"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "17203969",
                    "url": "https://glygen.org/publication/PubMed/17203969"
                }
            ]
        },
        {
            "title": "The phagosomal proteome in interferon-gamma-activated macrophages.",
            "journal": "Immunity",
            "date": "2009",
            "authors": "Trost M, English L, Lemieux S, Courcelles M, Desjardins M, Thibault P",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q923A2",
                    "url": "https://www.uniprot.org/uniprot/Q923A2"
                },
                {
                    "database": "iPTMnet",
                    "id": "Q923A2",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q923A2"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "19144319",
                    "url": "https://glygen.org/publication/PubMed/19144319"
                }
            ]
        },
        {
            "title": "Localization and function of mSpindly during mouse oocyte meiotic maturation.",
            "journal": "Cell cycle (Georgetown, Tex.)",
            "date": "2010",
            "authors": "Zhang QH, Wei L, Tong JS, Qi ST, Li S, Ou XH, Ouyang YC, Hou Y, An LG, Schatten H, Schatten H, Sun QY",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_081687",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_081687"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "20505367",
                    "url": "https://glygen.org/publication/PubMed/20505367"
                }
            ]
        },
        {
            "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.",
            "journal": "Cell",
            "date": "2010",
            "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q923A2",
                    "url": "https://www.uniprot.org/uniprot/Q923A2"
                },
                {
                    "database": "iPTMnet",
                    "id": "Q923A2",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q923A2"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "21183079",
                    "url": "https://glygen.org/publication/PubMed/21183079"
                }
            ]
        },
        {
            "title": "MRTFB suppresses colorectal cancer development through regulating SPDL1 and MCAM.",
            "journal": "Proceedings of the National Academy of Sciences of the United States of America",
            "date": "2019",
            "authors": "Kodama T, Marian TA, Lee H, Kodama M, Li J, Parmacek MS, Jenkins NA, Copeland NG, Wei Z",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_081687",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_081687"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "31690663",
                    "url": "https://glygen.org/publication/PubMed/31690663"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "mmu:70385",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:70385",
            "resource": "KEGG Pathway"
        },
        {
            "id": "R-MMU-141430",
            "name": "Inactivation of APC/C via direct inhibition of the APC/C complex",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-141430",
            "resource": "Reactome",
            "description": "Inactivation of APC/C via direct inhibition of the APC/C complex"
        },
        {
            "id": "R-MMU-141444",
            "name": "Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-141444",
            "resource": "Reactome",
            "description": "Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"
        },
        {
            "id": "R-MMU-2467813",
            "name": "Separation of Sister Chromatids",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-2467813",
            "resource": "Reactome",
            "description": "Separation of Sister Chromatids"
        },
        {
            "id": "R-MMU-2500257",
            "name": "Resolution of Sister Chromatid Cohesion",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-2500257",
            "resource": "Reactome",
            "description": "Resolution of Sister Chromatid Cohesion"
        },
        {
            "id": "R-MMU-5663220",
            "name": "RHO GTPases Activate Formins",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-5663220",
            "resource": "Reactome",
            "description": "RHO GTPases Activate Formins"
        },
        {
            "id": "R-MMU-68877",
            "name": "Mitotic Prometaphase",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-68877",
            "resource": "Reactome",
            "description": "Mitotic Prometaphase"
        },
        {
            "id": "R-MMU-9648025",
            "name": "EML4 and NUDC in mitotic spindle formation",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-9648025",
            "resource": "Reactome",
            "description": "EML4 and NUDC in mitotic spindle formation"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q3KR99-1",
            "protein_name": "Protein Spindly",
            "gene_name": "Spdl1",
            "tax_id": 10116,
            "organism": "Rattus norvegicus",
            "sequence": {
                "sequence": "MEADITNLRNKLKECEDERLKAAQYGLQLLERQTELQSQLDKCHEEMMTTAENYNQEKYALQREVELKSRMLESLSCECEALRQQQKAQLEQLEMQLHRSHRQEVHGLRNKLENLKVELDEARLSEKQLKQKLDHQGELLSHKSEELRLLSEQRALSSVSSELLSLQTELTEAEGVKNALREEVNELQCKQEQLECLNASLLHQVDRLKEEKEEREKEAVSYYNALEKARVENQDLQVQLGHALQQAADPNSKGNSLFAEVEDRRVAMERRLNLMKDKYQSLKKQNAFTRDQMNKMKLQISTLLRMRGSQTEFEQQERLFAMLEQKNGEIKHLLGEINKLEKFKNLYENMESKSSTSDSACALEDSTYYTDLLQLKLDKLNKENESTKGELSIQRMKALFESQRTLDIERKLFANERHLQLSESENLKLRAKLDELKLKYEPEERIEVPVLKRRREVLPLNINTPEETAAASATGEDVSRLPLERKEESCLDNLKDNTVQWKQPASLSPHKSLPLDTQPKKEKCVTLVASPASTEVLHEQSGNTPSSPRLTEESRLPTKVKERKEATSKLEKGASKKSHTIMYVSSKSTPEMQCPQQ",
                "length": 597
            },
            "evidence": [
                {
                    "id": "45240000",
                    "url": "http://www.informatics.jax.org/homology/45240000",
                    "database": "MGI"
                },
                {
                    "id": "Q923A2",
                    "url": "https://omabrowser.org/oma/group/Q923A2/",
                    "database": "OMA"
                }
            ],
            "common_name": "Rat"
        },
        {
            "uniprot_canonical_ac": "Q96EA4-1",
            "protein_name": "Protein Spindly",
            "gene_name": "SPDL1",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MEADIITNLRCRLKEAEEERLKAAQYGLQLVESQNELQNQLDKCRNEMMTMTESYEQEKYTLQREVELKSRMLESLSCECEAIKQQQKMHLEKLEEQLSRSHGQEVNELKTKIEKLKVELDEARLSEKQLKHQVDHQKELLSCKSEELRVMSERVQESMSSEMLALQIELTEMESMKTTLKEEVNELQYRQEQLELLITNLMRQVDRLKEEKEEREKEAVSYYNALEKARVANQDLQVQLDQALQQALDPNSKGNSLFAEVEDRRAAMERQLISMKVKYQSLKKQNVFNREQMQRMKLQIATLLQMKGSQTEFEQQERLLAMLEQKNGEIKHLLGEIRNLEKFKNLYDSMESKPSVDSGTLEDNTYYTDLLQMKLDNLNKEIESTKGELSIQRMKALFESQRALDIERKLFANERCLQLSESENMKLRAKLDELKLKYEPEETVEVPVLKKRREVLPVDITTAKDACVNNSALGGEVYRLPPQKEETQSCPNSLEDNNLQLEKSVSIYTPVVSLSPHKNLPVDMQLKKEKKCVKLIGVPADAEALSERSGNTPNSPRLAAESKLQTEVKEGKETSSKLEKETCKKLHPILYVSSKSTPETQCPQQ",
                "length": 605
            },
            "evidence": [
                {
                    "id": "45240000",
                    "url": "http://www.informatics.jax.org/homology/45240000",
                    "database": "MGI"
                },
                {
                    "id": "Q923A2",
                    "url": "https://omabrowser.org/oma/group/Q923A2/",
                    "database": "OMA"
                }
            ],
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Cellular Component",
                "total": 5,
                "go_terms": [
                    {
                        "name": "spindle pole",
                        "id": "GO:0000922",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q923A2",
                                "url": "https://www.uniprot.org/uniprot/Q923A2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "nucleus",
                        "id": "GO:0005634",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q923A2",
                                "url": "https://www.uniprot.org/uniprot/Q923A2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cytoplasm",
                        "id": "GO:0005737",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q923A2",
                                "url": "https://www.uniprot.org/uniprot/Q923A2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "microtubule organizing center",
                        "id": "GO:0005815",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005815",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q923A2",
                                "url": "https://www.uniprot.org/uniprot/Q923A2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "outer kinetochore",
                        "id": "GO:0000940",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000940",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q923A2",
                                "url": "https://www.uniprot.org/uniprot/Q923A2"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 6,
                "go_terms": [
                    {
                        "name": "cell migration",
                        "id": "GO:0016477",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q923A2",
                                "url": "https://www.uniprot.org/uniprot/Q923A2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cell division",
                        "id": "GO:0051301",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q923A2",
                                "url": "https://www.uniprot.org/uniprot/Q923A2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "mitotic spindle assembly checkpoint signaling",
                        "id": "GO:0007094",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007094",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q923A2",
                                "url": "https://www.uniprot.org/uniprot/Q923A2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "mitotic metaphase plate congression",
                        "id": "GO:0007080",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007080",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q923A2",
                                "url": "https://www.uniprot.org/uniprot/Q923A2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "establishment of mitotic spindle orientation",
                        "id": "GO:0000132",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000132",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q923A2",
                                "url": "https://www.uniprot.org/uniprot/Q923A2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "protein localization to kinetochore",
                        "id": "GO:0034501",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034501",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q923A2",
                                "url": "https://www.uniprot.org/uniprot/Q923A2"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 2,
                "go_terms": [
                    {
                        "name": "enzyme binding",
                        "id": "GO:0019899",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q923A2",
                                "url": "https://www.uniprot.org/uniprot/Q923A2"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "kinetochore binding",
                        "id": "GO:0043515",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043515",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q923A2",
                                "url": "https://www.uniprot.org/uniprot/Q923A2"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 198,
            "end_pos": 200,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 384,
            "end_pos": 386,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 461,
            "end_pos": 463,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [
        {
            "annotation": "Monoubiquitinated with'Lys-48' linkage (By similarity). Deubiquitinated by USP45 (By similarity).",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q923A2",
                    "url": "https://www.uniprot.org/uniprot/Q923A2"
                },
                {
                    "database": "PubMed",
                    "id": "Q96EA4",
                    "url": "https://glygen.org/publication/PubMed/Q96EA4"
                }
            ]
        }
    ],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        },
        {
            "name": "homologset.oma",
            "label": "OMA Homologs"
        }
    ],
    "section_stats": [
        {
            "table_id": "glycosylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported",
            "table_stats": [
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                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
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                },
                {
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                },
                {
                    "field": "n_linked_glycan_sites",
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                },
                {
                    "field": "o_linked_glycans",
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                },
                {
                    "field": "o_linked_glycan_sites",
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                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported_with_glycan",
            "table_stats": [
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                    "field": "total",
                    "count": 0
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                {
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                {
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                {
                    "field": "o_linked_glycans",
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                {
                    "field": "o_linked_glycan_sites",
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                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_predicted",
            "table_stats": [
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                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
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                },
                {
                    "field": "n_linked_glycans",
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                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
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                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_automatic_literature_mining",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
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                {
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                {
                    "field": "n_linked_glycan_sites",
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                {
                    "field": "o_linked_glycans",
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                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "phosphorylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 5
                },
                {
                    "field": "total_sites",
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                }
            ],
            "sort_fields": [
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                "kinase_uniprot_canonical_ac",
                "kinase_gene_name",
                "residue",
                "comment",
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            ]
        },
        {
            "table_id": "snv",
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                    "field": "total",
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                },
                {
                    "field": "total_sites",
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                }
            ],
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        },
        {
            "table_id": "snv_disease",
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                    "field": "total",
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                },
                {
                    "field": "total_sites",
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            ],
            "sort_fields": []
        },
        {
            "table_id": "snv_non_disease",
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                    "field": "total",
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                {
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            ],
            "sort_fields": []
        },
        {
            "table_id": "publication",
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                    "field": "total",
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                }
            ],
            "sort_fields": [
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        }
    ]
}