{
    "uniprot_canonical_ac": "Q920A1-1",
    "uniprot_ac": "Q920A1",
    "uniprot_id": "CLTR2_MOUSE",
    "mass": {
        "chemical_mass": 35213.0,
        "monoisotopic_mass": 35213.0
    },
    "refseq": {
        "ac": "NP_001155884",
        "name": "cysteinyl leukotriene receptor 2",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001155884"
    },
    "gene_names": [
        {
            "name": "Cysltr2",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/Q920A1",
            "id": "Q920A1"
        },
        {
            "name": "2300001H05Rik; Cltr2; Cyslt2; CYSLT2R",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001155884",
            "id": "NP_001155884"
        },
        {
            "name": "Cyslt2",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/Q920A1",
            "id": "Q920A1"
        },
        {
            "name": "Cysltr2",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001155884",
            "id": "NP_001155884"
        }
    ],
    "protein_names": [
        {
            "name": "Cysteinyl leukotriene receptor 2",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "Q920A1"
        },
        {
            "name": "CysLTR2",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q920A1"
        },
        {
            "name": "cysteinyl leukotriene receptor 2",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001155884",
            "id": "NP_001155884"
        }
    ],
    "function": [
        {
            "annotation": "Findings show that CysLT1 receptor attenuates while CysLT2 receptor facilitates oxygen glucose deprivation -induced PC12 cell death",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001155884",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001155884"
                },
                {
                    "database": "PubMed",
                    "id": "16756959",
                    "url": "https://glygen.org/publication/PubMed/16756959"
                }
            ]
        },
        {
            "annotation": "Receptor for cysteinyl leukotrienes. The response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTC4 = LTD4 >> LTE4.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q920A1",
                    "url": "https://www.uniprot.org/uniprot/Q920A1#function"
                }
            ]
        },
        {
            "annotation": "The CysLT2R receptor mediates leukotriene C4-driven acute and chronic itch.",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001155884",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001155884"
                },
                {
                    "database": "PubMed",
                    "id": "33753496",
                    "url": "https://glygen.org/publication/PubMed/33753496"
                }
            ]
        }
    ],
    "disease": [
        {
            "disease_id": "DOID:0050848",
            "recommended_name": {
                "id": "DOID:0050848",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0050848",
                "name": "obstructive sleep apnea",
                "description": "A sleep apnea that is characterized by repeated collapse and obstruction of the upper airway during sleep, which results in reduced airflow (hypopnea) or complete airflow cessation (apnea), oxygen desaturation, and arousals from sleep."
            },
            "synonyms": [
                {
                    "id": "DOID:0050848",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0050848",
                    "name": "obstructive sleep apnea syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0007147",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007147",
                    "name": "obstructive sleep apnea syndrome",
                    "description": "Cessation of air flow during sleep due to upper airway obstruction."
                },
                {
                    "id": "MONDO:0007147",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007147",
                    "name": "obstructive sleep apnea",
                    "description": ""
                },
                {
                    "id": "MONDO:0007147",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007147",
                    "name": "obstructive sleep apnea syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0007147",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007147",
                    "name": "Apneas, obstructive sleep",
                    "description": ""
                },
                {
                    "id": "MONDO:0007147",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007147",
                    "name": "OSAHS",
                    "description": ""
                },
                {
                    "id": "MONDO:0007147",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007147",
                    "name": "Osa",
                    "description": ""
                },
                {
                    "id": "MONDO:0007147",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007147",
                    "name": "apnea, obstructive sleep",
                    "description": ""
                },
                {
                    "id": "MONDO:0007147",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007147",
                    "name": "obstructive sleep Apneas",
                    "description": ""
                },
                {
                    "id": "MONDO:0007147",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007147",
                    "name": "sleep Apneas, obstructive",
                    "description": ""
                },
                {
                    "id": "MONDO:0007147",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007147",
                    "name": "sleep apnea hypopnea syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0007147",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007147",
                    "name": "sleep apnea syndrome, obstructive",
                    "description": ""
                },
                {
                    "id": "MONDO:0007147",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007147",
                    "name": "sleep apnea/hypopnea syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0007147",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007147",
                    "name": "syndrome, obstructive sleep apnea",
                    "description": ""
                },
                {
                    "id": "MONDO:0007147",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007147",
                    "name": "syndrome, sleep apnea, obstructive",
                    "description": ""
                },
                {
                    "id": "MONDO:0007147",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007147",
                    "name": "syndrome, upper airway resistance, sleep apnea",
                    "description": ""
                },
                {
                    "id": "MONDO:0007147",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007147",
                    "name": "upper airway resistance sleep apnea syndrome",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "0050848",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050848"
                }
            ]
        },
        {
            "disease_id": "DOID:0080822",
            "recommended_name": {
                "id": "DOID:0080822",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0080822",
                "name": "aspirin-induced respiratory disease",
                "description": "An intrinsic asthma that is characertized by severe and prolonged airway obstruction after the ingestion of aspirin or other non-steroidal anti-inflammatory drugs."
            },
            "synonyms": [
                {
                    "id": "DOID:0080822",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0080822",
                    "name": "aspirin-sensitive asthma",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "0080822",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080822"
                }
            ]
        },
        {
            "disease_id": "DOID:2841",
            "recommended_name": {
                "id": "DOID:2841",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:2841",
                "name": "asthma",
                "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing."
            },
            "synonyms": [
                {
                    "id": "DOID:2841",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:2841",
                    "name": "Exercise induced asthma",
                    "description": ""
                },
                {
                    "id": "DOID:2841",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:2841",
                    "name": "bronchial hyperreactivity",
                    "description": ""
                },
                {
                    "id": "DOID:2841",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:2841",
                    "name": "chronic obstructive asthma",
                    "description": ""
                },
                {
                    "id": "DOID:2841",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:2841",
                    "name": "chronic obstructive asthma with acute exacerbation",
                    "description": ""
                },
                {
                    "id": "DOID:2841",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:2841",
                    "name": "chronic obstructive asthma with status asthmaticus",
                    "description": ""
                },
                {
                    "id": "DOID:2841",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:2841",
                    "name": "exercise-induced asthma",
                    "description": ""
                },
                {
                    "id": "MONDO:0010940",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010940",
                    "name": "inherited susceptibility to asthma",
                    "description": ""
                },
                {
                    "id": "MONDO:0010940",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010940",
                    "name": "asthma, nocturnal, susceptibility to",
                    "description": ""
                },
                {
                    "id": "MONDO:0010940",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010940",
                    "name": "asthma, bronchial",
                    "description": ""
                },
                {
                    "id": "MONDO:0010940",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010940",
                    "name": "asthma, diminished response to Antileukotriene treatment 1N",
                    "description": ""
                },
                {
                    "id": "MONDO:0010940",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010940",
                    "name": "asthma, protection against",
                    "description": ""
                },
                {
                    "id": "MONDO:0010940",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010940",
                    "name": "asthma, susceptibility to",
                    "description": ""
                },
                {
                    "id": "MONDO:0010940",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010940",
                    "name": "asthma-related traits, susceptibility to",
                    "description": ""
                },
                {
                    "id": "MIM:600807",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/600807",
                    "name": "Asthma",
                    "description": "Asthma"
                }
            ],
            "evidence": [
                {
                    "id": "2841",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:2841"
                }
            ]
        },
        {
            "disease_id": "DOID:4483",
            "recommended_name": {
                "id": "DOID:4483",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:4483",
                "name": "rhinitis",
                "description": "A upper respiratory infectious disease which involves irritation and inflammation of the mucous membrane of the nose due to viruses, bacteria or irritants. The inflammation results in generation of excessive amounts of mucus leading to runny nose, as well as nasal congestion and post-nasal drip."
            },
            "synonyms": [],
            "evidence": [
                {
                    "id": "4483",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:4483"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q920A1",
                    "url": "https://www.uniprot.org/uniprot/Q920A1"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "gene": [
        {
            "name": "Cysltr2",
            "url": "https://www.uniprot.org/uniprot/Q920A1",
            "locus": {
                "chromosome": "14",
                "start_pos": 73263043,
                "end_pos": 73286554,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSMUSG00000033470",
                        "url": "https://www.ensembl.org/id/ENSMUSG00000033470"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSMUSG00000033470",
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000033470",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "70086",
            "url": "https://www.ncbi.nlm.nih.gov/gene/70086",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR000276",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR004071",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR004071",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR013311",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013311",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR017452",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "mmu:70086",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:70086",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "1917336",
            "url": "http://www.informatics.jax.org/marker/MGI:1917336",
            "database": "MGI",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "FCTIIVC",
            "url": "https://omabrowser.org/oma/group/FCTIIVC/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "2875155at2759",
            "url": "http://www.orthodb.org/?query=2875155at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR24231",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24231",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR24231:SF48",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24231:SF48",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00001",
            "url": "http://pfam.xfam.org/family/PF00001",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_Q920A1",
            "url": "http://purl.obolibrary.org/obo/PR_Q920A1",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "R-MMU-391906",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-391906",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-MMU-416476",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-416476",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "NP_001155884",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001155884",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q920A1",
            "url": "https://www.uniprot.org/uniprot/Q920A1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q920A1-1",
            "url": "https://www.uniprot.org/uniprot/Q920A1-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MEVTGTPSSYSNRNCTIENFKKEFYPIIYLIIFFWGALGNGFSIYVFLQTCKKSTSVNVFMLNLATSDFLFISTLPFRADYYFRGSNWIFGDLACRVMSYSLYVNMYTSIYFLTVLSVVRFLATVHPFRMFHVTSVRSAWILCGIIWVFIMASSALLLVNGQEEKDNIISCLELSPQKFKSLLIMNHIAVAVGFLLPFLTLTVCYLLIIRILLKAEIPESGPRAAHRKALTTIVIAMITFLLCFLPYHALRTLHLVTWDKDSCGDVLHKATVITLTMAAANSCFNPFLYYFAGENFKARLRAIFSKVHL",
        "length": 309,
        "header": "sp|Q920A1-1|CLTR2_MOUSE Isoform 1 of Cysteinyl leukotriene receptor 2  OS=Mus musculus OX=10090 GN=Cysltr2 PE=2 SV=2 CANONICAL=Q920A1-1"
    },
    "isoforms": [
        {
            "isoform_ac": "Q920A1-1",
            "url": "",
            "sequence": {
                "sequence": "MEVTGTPSSYSNRNCTIENFKKEFYPIIYLIIFFWGALGNGFSIYVFLQTCKKSTSVNVFMLNLATSDFLFISTLPFRADYYFRGSNWIFGDLACRVMSYSLYVNMYTSIYFLTVLSVVRFLATVHPFRMFHVTSVRSAWILCGIIWVFIMASSALLLVNGQEEKDNIISCLELSPQKFKSLLIMNHIAVAVGFLLPFLTLTVCYLLIIRILLKAEIPESGPRAAHRKALTTIVIAMITFLLCFLPYHALRTLHLVTWDKDSCGDVLHKATVITLTMAAANSCFNPFLYYFAGENFKARLRAIFSKVHL",
                "length": 309,
                "header": "sp|Q920A1-1|CLTR2_MOUSE Isoform 1 of Cysteinyl leukotriene receptor 2  OS=Mus musculus OX=10090 GN=Cysltr2 PE=2 SV=2 CANONICAL=Q920A1-1"
            },
            "locus": {
                "chromosome": "14",
                "start_pos": 73267708,
                "end_pos": 73266782,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000044664",
                        "url": "https://www.ensembl.org/id/ENSMUST00000044664"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000040715",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000040715"
                    }
                ]
            }
        }
    ],
    "glycosylation": [
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 14,
            "start_aa": "Asn",
            "end_pos": 14,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn14",
            "evidence": [
                {
                    "id": "Q920A1",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/Q920A1#ptm_processing"
                }
            ]
        }
    ],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [
        "glycoprotein",
        "glycoprotein_predicted"
    ],
    "publication": [
        {
            "title": "The murine cysteinyl leukotriene 2 (CysLT2) receptor. cDNA and genomic cloning, alternative splicing, and in vitro characterization.",
            "journal": "J. Biol. Chem.",
            "date": "2001",
            "authors": "Copeland N.G., Gilbert D.J., Jenkins N.A., Yang G., Austin C.P., Figueroa D.J., Funk C.D., Hui Y., Galczenski H.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q920A1",
                    "url": "https://www.uniprot.org/uniprot/Q920A1"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "11591709",
                    "url": "https://glygen.org/publication/PubMed/11591709"
                }
            ]
        },
        {
            "title": "Distinct roles of CysLT1 and CysLT2 receptors in oxygen glucose deprivation-induced PC12 cell death.",
            "journal": "Biochemical and biophysical research communications",
            "date": "2006",
            "authors": "Sheng WW, Li CT, Zhang WP, Yuan YM, Hu H, Fang SH, Zhang L, Wei EQ",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001155884",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001155884"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "16756959",
                    "url": "https://glygen.org/publication/PubMed/16756959"
                }
            ]
        },
        {
            "title": "The CysLT2R receptor mediates leukotriene C4-driven acute and chronic itch.",
            "journal": "Proceedings of the National Academy of Sciences of the United States of America",
            "date": "2021",
            "authors": "Voisin T, Perner C, Messou MA, Shiers S, Ualiyeva S, Kanaoka Y, Price TJ, Sokol CL, Bankova LG, Austen KF, Chiu IM",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001155884",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001155884"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "33753496",
                    "url": "https://glygen.org/publication/PubMed/33753496"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "mmu:70086",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:70086",
            "resource": "KEGG Pathway"
        },
        {
            "id": "R-MMU-391906",
            "name": "Leukotriene receptors",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-391906",
            "resource": "Reactome",
            "description": "Leukotriene receptors"
        },
        {
            "id": "R-MMU-416476",
            "name": "G alpha (q) signalling events",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-416476",
            "resource": "Reactome",
            "description": "G alpha (q) signalling events"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q924T9-1",
            "protein_name": "Cysteinyl leukotriene receptor 2",
            "gene_name": "Cysltr2",
            "tax_id": 10116,
            "organism": "Rattus norvegicus",
            "sequence": {
                "sequence": "MGVTGTPSYYSDKNCTIENFKRDFYPIIYLIIFVWGALGNGFSIYVFLQTYKKSTSVNVFMLNLAISDFLFISTLPFRADYNFRGSDWIFGDWACRIMSYSLYVNMYTSIYFLTVLSIVRFLATAHPFQMLHITSVRSAWILCGIIWVFIMASSGLLLKHGQEKKNNTTLCFELNLQKFKNLVILNYIALGVGFLLPFFILTICYLLIIRVLLKVEIPESGPRDAQRKALTTIVIAMIIFLLCFLPYHALRTIHLVTWDADSCMDELHKATVITLTLAAANSCFNPFLYYFAGENFKARLRAIFSKDHL",
                "length": 309
            },
            "evidence": [
                {
                    "id": "45229392",
                    "url": "http://www.informatics.jax.org/homology/45229392",
                    "database": "MGI"
                },
                {
                    "id": "Q920A1",
                    "url": "https://omabrowser.org/oma/group/Q920A1/",
                    "database": "OMA"
                }
            ],
            "common_name": "Rat"
        },
        {
            "uniprot_canonical_ac": "Q9NS75-1",
            "protein_name": "Cysteinyl leukotriene receptor 2",
            "gene_name": "CYSLTR2",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MERKFMSLQPSISVSEMEPNGTFSNNNSRNCTIENFKREFFPIVYLIIFFWGVLGNGLSIYVFLQPYKKSTSVNVFMLNLAISDLLFISTLPFRADYYLRGSNWIFGDLACRIMSYSLYVNMYSSIYFLTVLSVVRFLAMVHPFRLLHVTSIRSAWILCGIIWILIMASSIMLLDSGSEQNGSVTSCLELNLYKIAKLQTMNYIALVVGCLLPFFTLSICYLLIIRVLLKVEVPESGLRVSHRKALTTIIITLIIFFLCFLPYHTLRTVHLTTWKVGLCKDRLHKALVITLALAAANACFNPLLYYFAGENFKDRLKSALRKGHPQKAKTKCVFPVSVWLRKETRV",
                "length": 346
            },
            "evidence": [
                {
                    "id": "45229392",
                    "url": "http://www.informatics.jax.org/homology/45229392",
                    "database": "MGI"
                },
                {
                    "id": "Q920A1",
                    "url": "https://omabrowser.org/oma/group/Q920A1/",
                    "database": "OMA"
                }
            ],
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Cellular Component",
                "total": 2,
                "go_terms": [
                    {
                        "name": "plasma membrane",
                        "id": "GO:0005886",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q920A1",
                                "url": "https://www.uniprot.org/uniprot/Q920A1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "membrane",
                        "id": "GO:0016020",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q920A1",
                                "url": "https://www.uniprot.org/uniprot/Q920A1"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 5,
                "go_terms": [
                    {
                        "name": "neuropeptide signaling pathway",
                        "id": "GO:0007218",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007218",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q920A1",
                                "url": "https://www.uniprot.org/uniprot/Q920A1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of ERK1 and ERK2 cascade",
                        "id": "GO:0070374",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070374",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q920A1",
                                "url": "https://www.uniprot.org/uniprot/Q920A1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of angiogenesis",
                        "id": "GO:0045766",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045766",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q920A1",
                                "url": "https://www.uniprot.org/uniprot/Q920A1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "negative regulation of glial cell proliferation",
                        "id": "GO:0060253",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060253",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q920A1",
                                "url": "https://www.uniprot.org/uniprot/Q920A1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cellular response to oxygen-glucose deprivation",
                        "id": "GO:0090650",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090650",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q920A1",
                                "url": "https://www.uniprot.org/uniprot/Q920A1"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 2,
                "go_terms": [
                    {
                        "name": "G protein-coupled peptide receptor activity",
                        "id": "GO:0008528",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008528",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q920A1",
                                "url": "https://www.uniprot.org/uniprot/Q920A1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cysteinyl leukotriene receptor activity",
                        "id": "GO:0001631",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001631",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q920A1",
                                "url": "https://www.uniprot.org/uniprot/Q920A1"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 14,
            "end_pos": 16,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        },
        {
            "name": "homologset.oma",
            "label": "OMA Homologs"
        }
    ],
    "section_stats": [
        {
            "table_id": "glycosylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 1
                },
                {
                    "field": "total_sites",
                    "count": 1
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 1
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": [
                "glytoucan_ac",
                "type",
                "subtype",
                "site_category",
                "site_seq",
                "relation",
                "comment",
                "start_pos",
                "start_aa",
                "end_pos",
                "end_aa",
                "residue",
                "site_lbl"
            ]
        },
        {
            "table_id": "glycosylation_reported",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported_with_glycan",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_predicted",
            "table_stats": [
                {
                    "field": "total",
                    "count": 1
                },
                {
                    "field": "total_sites",
                    "count": 1
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 1
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": [
                "glytoucan_ac",
                "type",
                "subtype",
                "site_category",
                "site_seq",
                "relation",
                "comment",
                "start_pos",
                "start_aa",
                "end_pos",
                "end_aa",
                "residue",
                "site_lbl"
            ]
        },
        {
            "table_id": "glycosylation_automatic_literature_mining",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "phosphorylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "snv",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "snv_disease",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "snv_non_disease",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "publication",
            "table_stats": [
                {
                    "field": "total",
                    "count": 3
                }
            ],
            "sort_fields": [
                "title",
                "journal",
                "date",
                "authors"
            ]
        }
    ]
}