{ "uniprot_canonical_ac": "Q91VF6-1", "uniprot_ac": "Q91VF6", "uniprot_id": "COQA1_MOUSE", "mass": { "chemical_mass": 45810.0, "monoisotopic_mass": 45810.0 }, "refseq": { "ac": "NP_001333628", "name": "collagen alpha-1(XXVI) chain isoform 2 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001333628" }, "gene_names": [ { "name": "Col26a1", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/Q91VF6", "id": "Q91VF6" }, { "name": "9430032K24Rik; Col26a; Emid2; Emu2", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001333628", "id": "NP_001333628" }, { "name": "Col26a1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001333628", "id": "NP_001333628" }, { "name": "Col26a", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q91VF6", "id": "Q91VF6" }, { "name": "Emid2", "resource": "UniProtKB", "type": "synonym", 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musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q91VF6", "url": "https://www.uniprot.org/uniprot/Q91VF6" } ], "common_name": "Mouse" } ], "gene": [ { "name": "Col26a1", "url": "https://www.uniprot.org/uniprot/Q91VF6", "locus": { "chromosome": "5", "start_pos": 136770613, "end_pos": 136912063, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSMUSG00000004415", "url": "https://www.ensembl.org/id/ENSMUSG00000004415" } ] } } ], "crossref": [ { "id": "ENSMUSG00000004415", "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000004415", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "140709", "url": "https://www.ncbi.nlm.nih.gov/gene/140709", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011489", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011489", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "mmu:140709", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:140709", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "2155345", "url": "http://www.informatics.jax.org/marker/MGI:2155345", "database": "MGI", "categories": [ "Organism-specific" ] }, { "id": "PPPWNEG", "url": "https://omabrowser.org/oma/group/PPPWNEG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "3062338at2759", "url": "http://www.orthodb.org/?query=3062338at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15427", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15427", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15427:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15427:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01391", "url": "http://pfam.xfam.org/family/PF01391", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF07546", "url": "http://pfam.xfam.org/family/PF07546", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PR_Q91VF6", "url": "http://purl.obolibrary.org/obo/PR_Q91VF6", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-MMU-1442490", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-1442490", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "R-MMU-1650814", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-1650814", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "R-MMU-8948216", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-8948216", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "NP_001333628", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001333628", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q91VF6", "url": "https://www.uniprot.org/uniprot/Q91VF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q91VF6-1", "url": "https://www.uniprot.org/uniprot/Q91VF6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q91VF6-2", "url": "https://www.uniprot.org/uniprot/Q91VF6-2", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKLVLLLPWACCCLCGSALATGFLYPFPAAALQQHGYPEQGAGSPGNGYSSRRHWCHHTVTRTVSCQVQNGSETVVQRVYQSCRWPGPCANLVSYRTLIRPTYRVSYRTVTALEWRCCPGFTGSNCEEECMNCTRLSDMSERLTTLEAKVLLLEAAEQPSGPDNDLPPPQSTPPTWNEDFLPDAIPIAHPGPRRRRPTGPAGPPGQMGPPGPAGPPGSKGEQGQTGEKGPVGPPGLLGPPGPRGLPGEMGRPGPPGPPGPAGSPGLLPNTPQGVLYSLQTPTDKENGDSQLNPAVVDTVLTGIPGPRGPPGPPGPPGPHGPPGPPGAPGSQGLVDERVVARPSGEPSVKEEEDKASAAEGEGVQQLREALKILAERVLILEHMIGVHDPLASPEGGSGQDAALRANLKMKRGGPRPDGILAALLGPDPAQKSADQAGDRK", "length": 440, "header": "sp|Q91VF6-1|COQA1_MOUSE Isoform 1 of Collagen alpha-1(XXVI) chain OS=Mus musculus OX=10090 GN=Col26a1 PE=1 SV=1 CANONICAL=Q91VF6-1" }, "isoforms": [ { "isoform_ac": "Q91VF6-1", "url": "", "sequence": { "sequence": "MKLVLLLPWACCCLCGSALATGFLYPFPAAALQQHGYPEQGAGSPGNGYSSRRHWCHHTVTRTVSCQVQNGSETVVQRVYQSCRWPGPCANLVSYRTLIRPTYRVSYRTVTALEWRCCPGFTGSNCEEECMNCTRLSDMSERLTTLEAKVLLLEAAEQPSGPDNDLPPPQSTPPTWNEDFLPDAIPIAHPGPRRRRPTGPAGPPGQMGPPGPAGPPGSKGEQGQTGEKGPVGPPGLLGPPGPRGLPGEMGRPGPPGPPGPAGSPGLLPNTPQGVLYSLQTPTDKENGDSQLNPAVVDTVLTGIPGPRGPPGPPGPPGPHGPPGPPGAPGSQGLVDERVVARPSGEPSVKEEEDKASAAEGEGVQQLREALKILAERVLILEHMIGVHDPLASPEGGSGQDAALRANLKMKRGGPRPDGILAALLGPDPAQKSADQAGDRK", "length": 440, "header": "sp|Q91VF6-1|COQA1_MOUSE Isoform 1 of Collagen alpha-1(XXVI) chain OS=Mus musculus OX=10090 GN=Col26a1 PE=1 SV=1 CANONICAL=Q91VF6-1" }, "locus": { "chromosome": "5", "start_pos": 136911861, "end_pos": 136771903, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000057497", "url": "https://www.ensembl.org/id/ENSMUST00000057497" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000052095", "url": "https://www.ensembl.org/id/ENSMUSP00000052095" } ] } }, { "isoform_ac": "Q91VF6-2", "url": "", "sequence": { "sequence": "MKLVLLLPWACCCLCGSALATGFLYPFPAAALQQHGYPEQGAGSPGNGYSSRRHWCHHTVTRTVSCQVQNGSETVVQRVYQSCRWPGPCANLVRTLIRPTYRVSYRTVTALEWRCCPGFTGSNCEEECMNCTRLSDMSERLTTLEAKVLLLEAAEQPSGPDNDLPPPQSTPPTWNEDFLPDAIPIAHPGPRRRRPTGPAGPPGQMGPPGPAGPPGSKGEQGQTGEKGPVGPPGLLGPPGPRGLPGEMGRPGPPGPPGPAGSPGLLPNTPQGVLYSLQTPTDKENGDSQLNPAVVDTVLTGIPGPRGPPGPPGPPGPHGPPGPPGAPGSQGLVDERVVARPSGEPSVKEEEDKASAAEGEGVQQLREALKILAERVLILEHMIGVHDPLASPEGGSGQDAALRANLKMKRGGPRPDGILAALLGPDPAQKSADQAGDRK", "length": 438, "header": "sp|Q91VF6-2|COQA1_MOUSE Isoform 2 of Collagen alpha-1(XXVI) chain OS=Mus musculus OX=10090 GN=Col26a1 PE=1 SV=1 CANONICAL=Q91VF6-1" }, "locus": { "chromosome": "5", "start_pos": 136911861, "end_pos": 136771903, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000111103", "url": "https://www.ensembl.org/id/ENSMUST00000111103" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000106732", "url": "https://www.ensembl.org/id/ENSMUSP00000106732" } ] } } ], "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "predicted", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 132, "start_aa": "Asn", "end_pos": 132, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn132", "evidence": [ { "id": "Q91VF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91VF6#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "site_category": "predicted", "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "start_pos": 70, "start_aa": "Asn", "end_pos": 70, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn70", "evidence": [ { "id": "Q91VF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprot/Q91VF6#ptm_processing" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Type XXVI collagen, a new member of the collagen family, is specifically expressed in the testis and ovary.", "journal": "J. Biol. Chem.", "date": "2002", "authors": "Sato K, Yomogida K, Wada T, Yorihuzi T, Nishimune Y, Hosokawa N, Nagata K", "evidence": [ { "database": "UniProtKB", "id": "Q91VF6", "url": "https://www.uniprot.org/uniprot/Q91VF6" } ], "reference": [ { "type": "PubMed", "id": "12145293", "url": "https://glygen.org/publication/PubMed/12145293" } ] }, { "title": "Developmental expression and biochemical characterization of Emu family members.", "journal": "Dev. Biol.", "date": "2002", "authors": "Gessler M., Erhard S., Leimeister C., Schumacher N., Steidl C.", "evidence": [ { "database": "UniProtKB", "id": "Q91VF6", "url": "https://www.uniprot.org/uniprot/Q91VF6" } ], "reference": [ { "type": "PubMed", "id": "12221002", "url": "https://glygen.org/publication/PubMed/12221002" } ] } ], "pathway": [ { "id": "mmu:140709", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:140709", "resource": "KEGG Pathway" }, { "id": "R-MMU-1442490", "name": "Collagen degradation", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-1442490", "resource": "Reactome", "description": "Collagen degradation" }, { "id": "R-MMU-1650814", "name": "Collagen biosynthesis and modifying enzymes", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-1650814", "resource": "Reactome", "description": "Collagen biosynthesis and modifying enzymes" }, { "id": "R-MMU-8948216", "name": "Collagen chain trimerization", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-8948216", "resource": "Reactome", "description": "Collagen chain trimerization" } ], "orthologs": [ { "uniprot_canonical_ac": "Q96A83-1", "protein_name": "Collagen alpha-1(XXVI) chain", "gene_name": "COL26A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKLALLLPWACCCLCGSALATGFLYPFSAAALQQHGYPEPGAGSPGSGYASRRHWCHHTVTRTVSCQVQNGSETVVQRVYQSCRWPGPCANLVSYRTLIRPTYRVSYRTVTVLEWRCCPGFTGSNCDEECMNCTRLSDMSERLTTLEAKVLLLEAAERPSSPDNDLPAPESTPPTWNEDFLPDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAEGEGVQQLREALKILAERVLILEHMIGIHDPLASPEGGSGQDAALRANLKMKRGGAQPDGVLAALLGPDPGQKSVDQASSRK", "length": 441 }, "evidence": [ { "id": "45240873", "url": "http://www.informatics.jax.org/homology/45240873", "database": "MGI" }, { "id": "Q91VF6", "url": "https://omabrowser.org/oma/group/Q91VF6/", "database": "OMA" } ], "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q91VF6", "url": "https://www.uniprot.org/uniprot/Q91VF6" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "Q91VF6", "url": "https://www.uniprot.org/uniprot/Q91VF6" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q91VF6", "url": "https://www.uniprot.org/uniprot/Q91VF6" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "Q91VF6", "url": "https://www.uniprot.org/uniprot/Q91VF6" } ], "pmid": "" }, { "name": "collagen trimer", "id": "GO:0005581", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005581", "evidence": [ { "database": "UniProtKB", "id": "Q91VF6", "url": "https://www.uniprot.org/uniprot/Q91VF6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of cell-substrate adhesion", "id": "GO:0010811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010811", "evidence": [ { "database": "UniProtKB", "id": "Q91VF6", "url": "https://www.uniprot.org/uniprot/Q91VF6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 132, "end_pos": 134, "annotation": "n_glycosylation_sequon" }, { "start_pos": 70, "end_pos": 72, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "synthesized_glycans": [], "cluster_types": [ { 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