{
    "uniprot_canonical_ac": "Q8VBV9-1",
    "uniprot_ac": "Q8VBV9",
    "uniprot_id": "O51E2_MOUSE",
    "mass": {
        "chemical_mass": 35578.0,
        "monoisotopic_mass": 35578.0
    },
    "refseq": {
        "ac": "NP_001161975",
        "name": "olfactory receptor 51E2",
        "summary": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008].",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001161975"
    },
    "gene_names": [
        {
            "name": "Or51e2",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/Q8VBV9",
            "id": "Q8VBV9"
        },
        {
            "name": "4633402A21Rik; MOL2.3; MOR18-2; Olfr78; PSGR; RA1c",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001161975",
            "id": "NP_001161975"
        },
        {
            "name": "Mol2.3",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/Q8VBV9",
            "id": "Q8VBV9"
        },
        {
            "name": "Olfr78",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/Q8VBV9",
            "id": "Q8VBV9"
        },
        {
            "name": "Or51e2",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001161975",
            "id": "NP_001161975"
        },
        {
            "name": "Psgr",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/Q8VBV9",
            "id": "Q8VBV9"
        }
    ],
    "protein_names": [
        {
            "name": "Olfactory receptor 51E2",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "Q8VBV9"
        },
        {
            "name": "GA_x6K02T2PBJ9-5459657-5458695; olfactory receptor MOR18-2; olfactory receptor 78",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001161975",
            "id": "NP_001161975"
        },
        {
            "name": "Olfactory receptor 78",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q8VBV9"
        },
        {
            "name": "olfactory receptor 51E2",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001161975",
            "id": "NP_001161975"
        }
    ],
    "function": [
        {
            "annotation": "Olfactory receptor 78 is expressed in hypothalamic vasopressin/oxytocin neurons, parenchymal microglia and choroidal macrophages in mice. Publication Status: Online-Only",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001161975",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001161975"
                },
                {
                    "database": "PubMed",
                    "id": "35379313",
                    "url": "https://glygen.org/publication/PubMed/35379313"
                }
            ]
        },
        {
            "annotation": "Olfactory receptor 78 modulates renin but not baseline blood pressure.",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001161975",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001161975"
                },
                {
                    "database": "PubMed",
                    "id": "34549531",
                    "url": "https://glygen.org/publication/PubMed/34549531"
                }
            ]
        },
        {
            "annotation": "Olfactory receptor Olfr78 (prostate-specific G protein-coupled receptor PSGR) expression in arterioles supplying skeletal and cardiac muscles and in arterioles feeding some murine organs.",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001161975",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001161975"
                },
                {
                    "database": "PubMed",
                    "id": "34545457",
                    "url": "https://glygen.org/publication/PubMed/34545457"
                }
            ]
        },
        {
            "annotation": "Olfactory receptor. The activity of this receptor is probably mediated by G-proteins wich induce elevation of intracellular Ca(2+), cAMP and activation of phosphorylation of the protein kinases PKA and MAPK3/MAPK1. Activation of OR51E2 may affect melanocyte proliferation, differentiation, and melanogenesis and may increase proliferation and migration of primary retinal pigment epithelial (RPE) cells (By similarity). Activated by the short chain fatty acids (SCFA), acetate and propionate (PubMed:23401498). In response to SCFA, may positively regulate renin secretion and increase blood pressure (PubMed:23401498). May also be activated by steroid hormones and regulate cell proliferation (By similarity). Activated by L-lactate in glomus cells (PubMed:26560302, PubMed:30258151).",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8VBV9",
                    "url": "https://www.uniprot.org/uniprot/Q8VBV9#function"
                },
                {
                    "database": "PubMed",
                    "id": "23401498",
                    "url": "https://glygen.org/publication/PubMed/23401498"
                },
                {
                    "database": "UniProtKB",
                    "id": "Q9H255",
                    "url": "https://www.uniprot.org/uniprot/Q9H255#function"
                },
                {
                    "database": "PubMed",
                    "id": "26560302",
                    "url": "https://glygen.org/publication/PubMed/26560302"
                },
                {
                    "database": "PubMed",
                    "id": "30258151",
                    "url": "https://glygen.org/publication/PubMed/30258151"
                }
            ]
        },
        {
            "annotation": "Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008].",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001161975",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001161975"
                }
            ]
        },
        {
            "annotation": "The macrophage odorant receptor Olfr78 mediates the lactate-induced M2 phenotype of tumor-associated macrophages.",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001161975",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001161975"
                },
                {
                    "database": "PubMed",
                    "id": "34504016",
                    "url": "https://glygen.org/publication/PubMed/34504016"
                }
            ]
        },
        {
            "annotation": "Vagal neuron expression of the microbiota-derived metabolite receptor, free fatty acid receptor (FFAR3), is necessary for normal feeding behavior.",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001161975",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001161975"
                },
                {
                    "database": "PubMed",
                    "id": "34626852",
                    "url": "https://glygen.org/publication/PubMed/34626852"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8VBV9",
                    "url": "https://www.uniprot.org/uniprot/Q8VBV9"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "gene": [
        {
            "name": "Or51e2",
            "url": "https://www.uniprot.org/uniprot/Q8VBV9",
            "locus": {
                "chromosome": "7",
                "start_pos": 102387718,
                "end_pos": 102408678,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSMUSG00000043366",
                        "url": "https://www.ensembl.org/id/ENSMUSG00000043366"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSMUSG00000043366",
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000043366",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "cd15222",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15222",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "170639",
            "url": "https://www.ncbi.nlm.nih.gov/gene/170639",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR000276",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR000725",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR017452",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "mmu:170639",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:170639",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "2157548",
            "url": "http://www.informatics.jax.org/marker/MGI:2157548",
            "database": "MGI",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "DMMKLAY",
            "url": "https://omabrowser.org/oma/group/DMMKLAY/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "4578140at2759",
            "url": "http://www.orthodb.org/?query=4578140at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR26450",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR26450:SF92",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450:SF92",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF13853",
            "url": "http://pfam.xfam.org/family/PF13853",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_Q8VBV9",
            "url": "http://purl.obolibrary.org/obo/PR_Q8VBV9",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "R-MMU-381753",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-381753",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "NP_001161975",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001161975",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q8VBV9",
            "url": "https://www.uniprot.org/uniprot/Q8VBV9",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "Q8VBV9-1",
            "url": "https://www.uniprot.org/uniprot/Q8VBV9-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MSSCNFTHATFLLIGIPGLEEAHFWFGFPLLSMYAVALFGNCIVVFIVRTERSLHAPMYLFLCMLAAIDLALSTSTMPKILALFWFDSREITFDACLAQMFFIHTLSAIESTILLAMAFDRYVAICHPLRHAAVLNNTVTVQIGMVALVRGSLFFFPLPLLIKRLAFCHSNVLSHSYCVHQDVMKLAYTDTLPNVVYGLTAILLVMGVDVMFISLSYFLIIRTVLQLPSKSERAKAFGTCVSHISVVLAFYVPLIGLSVVHRFGNSLDPIVHVLMGDVYLLLPPVINPIIYGAKTKQIRTRVLAMFKISCDKDIEAGGNT",
        "length": 320,
        "header": "sp|Q8VBV9-1|O51E2_MOUSE Isoform 1 of Olfactory receptor 51E2  OS=Mus musculus OX=10090 GN=Or51e2 PE=2 SV=1 CANONICAL=Q8VBV9-1"
    },
    "isoforms": [
        {
            "isoform_ac": "Q8VBV9-1",
            "url": "",
            "sequence": {
                "sequence": "MSSCNFTHATFLLIGIPGLEEAHFWFGFPLLSMYAVALFGNCIVVFIVRTERSLHAPMYLFLCMLAAIDLALSTSTMPKILALFWFDSREITFDACLAQMFFIHTLSAIESTILLAMAFDRYVAICHPLRHAAVLNNTVTVQIGMVALVRGSLFFFPLPLLIKRLAFCHSNVLSHSYCVHQDVMKLAYTDTLPNVVYGLTAILLVMGVDVMFISLSYFLIIRTVLQLPSKSERAKAFGTCVSHISVVLAFYVPLIGLSVVHRFGNSLDPIVHVLMGDVYLLLPPVINPIIYGAKTKQIRTRVLAMFKISCDKDIEAGGNT",
                "length": 320,
                "header": "sp|Q8VBV9-1|O51E2_MOUSE Isoform 1 of Olfactory receptor 51E2  OS=Mus musculus OX=10090 GN=Or51e2 PE=2 SV=1 CANONICAL=Q8VBV9-1"
            },
            "locus": {
                "chromosome": "7",
                "start_pos": 102392208,
                "end_pos": 102391249,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000168007",
                        "url": "https://www.ensembl.org/id/ENSMUST00000168007"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000133255",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000133255"
                    }
                ]
            }
        }
    ],
    "glycosylation": [
        {
            "glytoucan_ac": "",
            "type": "N-linked",
            "subtype": "",
            "site_category": "predicted",
            "site_seq": "N",
            "relation": "attached",
            "comment": "N-linked (GlcNAc...) asparagine",
            "start_pos": 5,
            "start_aa": "Asn",
            "end_pos": 5,
            "end_aa": "Asn",
            "residue": "Asn",
            "site_lbl": "Asn5",
            "evidence": [
                {
                    "id": "Q8VBV9",
                    "database": "UniProtKB",
                    "url": "https://www.uniprot.org/uniprot/Q8VBV9#ptm_processing"
                }
            ]
        }
    ],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [
        "glycoprotein",
        "glycoprotein_predicted"
    ],
    "publication": [
        {
            "title": "A novel brain receptor is expressed in a distinct population of olfactory sensory neurons.",
            "journal": "Eur. J. Neurosci.",
            "date": "2000",
            "authors": "Conzelmann S, Levai O, Bode B, Eisel U, Raming K, Breer H, Strotmann J",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8VBV9",
                    "url": "https://www.uniprot.org/uniprot/Q8VBV9"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "11069588",
                    "url": "https://glygen.org/publication/PubMed/11069588"
                }
            ]
        },
        {
            "title": "Cloning and genetic characterization of an evolutionarily conserved human olfactory receptor that is differentially expressed across species.",
            "journal": "Gene",
            "date": "2001",
            "authors": "Lin R.J., McClary J.A., Miyamoto N.G., Kretschmer P.J., Toy P., Yuan T.T.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8VBV9",
                    "url": "https://www.uniprot.org/uniprot/Q8VBV9"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "11707321",
                    "url": "https://glygen.org/publication/PubMed/11707321"
                }
            ]
        },
        {
            "title": "Olfactory receptor responding to gut microbiota-derived signals plays a role in renin secretion and blood pressure regulation.",
            "journal": "Proc. Natl. Acad. Sci. U.S.A.",
            "date": "2013",
            "authors": "Pluznick JL, Protzko RJ, Gevorgyan H, Peterlin Z, Sipos A, Han J, Brunet I, Wan LX, Rey F, Wang T, Firestein SJ, Yanagisawa M, Gordon JI, Eichmann A, Peti-Peterdi J, Caplan MJ",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8VBV9",
                    "url": "https://www.uniprot.org/uniprot/Q8VBV9"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "23401498",
                    "url": "https://glygen.org/publication/PubMed/23401498"
                }
            ]
        },
        {
            "title": "Oxygen regulation of breathing through an olfactory receptor activated by lactate.",
            "journal": "Nature",
            "date": "2015",
            "authors": "Chang AJ, Ortega FE, Riegler J, Madison DV, Krasnow MA",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8VBV9",
                    "url": "https://www.uniprot.org/uniprot/Q8VBV9"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "26560302",
                    "url": "https://glygen.org/publication/PubMed/26560302"
                }
            ]
        },
        {
            "title": "The role of Olfr78 in the breathing circuit of mice.",
            "journal": "Nature",
            "date": "2018",
            "authors": "Zhou T., Johnson R.S., Matsunami H., Mombaerts P., Lopez-Barneo J., Ortega-Saenz P., Macias D., Omura M., Torres-Torrelo H.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8VBV9",
                    "url": "https://www.uniprot.org/uniprot/Q8VBV9"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "30258151",
                    "url": "https://glygen.org/publication/PubMed/30258151"
                }
            ]
        },
        {
            "title": "Chang et al. reply.",
            "journal": "Nature",
            "date": "2018",
            "authors": "Kim N.S., Krasnow M.A., Chang A.J., Hireed H., Madison D.V., Ortega F.E., Riegler J., de Arce A.D.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8VBV9",
                    "url": "https://www.uniprot.org/uniprot/Q8VBV9"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "30258152",
                    "url": "https://glygen.org/publication/PubMed/30258152"
                }
            ]
        },
        {
            "title": "The macrophage odorant receptor Olfr78 mediates the lactate-induced M2 phenotype of tumor-associated macrophages.",
            "journal": "Proceedings of the National Academy of Sciences of the United States of America",
            "date": "2021",
            "authors": "Vadevoo SMP, Gunassekaran GR, Lee C, Lee N, Lee J, Chae S, Park JY, Koo J, Lee B",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001161975",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001161975"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "34504016",
                    "url": "https://glygen.org/publication/PubMed/34504016"
                }
            ]
        },
        {
            "title": "Olfactory receptor Olfr78 (prostate-specific G protein-coupled receptor PSGR) expression in arterioles supplying skeletal and cardiac muscles and in arterioles feeding some murine organs.",
            "journal": "Histochemistry and cell biology",
            "date": "2021",
            "authors": "Mermer P, Strotmann J, Kummer W, Paddenberg R",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001161975",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001161975"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "34545457",
                    "url": "https://glygen.org/publication/PubMed/34545457"
                }
            ]
        },
        {
            "title": "Olfactory receptor 78 modulates renin but not baseline blood pressure.",
            "journal": "Physiological reports",
            "date": "2021",
            "authors": "Poll BG, Xu J, Gupta K, Shubitowski TB, Pluznick JL",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001161975",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001161975"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "34549531",
                    "url": "https://glygen.org/publication/PubMed/34549531"
                }
            ]
        },
        {
            "title": "Vagal neuron expression of the microbiota-derived metabolite receptor, free fatty acid receptor (FFAR3), is necessary for normal feeding behavior.",
            "journal": "Molecular metabolism",
            "date": "2021",
            "authors": "Cook TM, Gavini CK, Jesse J, Aubert G, Gornick E, Bonomo R, Gautron L, Layden BT, Mansuy-Aubert V",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001161975",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001161975"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "34626852",
                    "url": "https://glygen.org/publication/PubMed/34626852"
                }
            ]
        },
        {
            "title": "Olfactory receptor 78 is expressed in hypothalamic vasopressin/oxytocin neurons, parenchymal microglia and choroidal macrophages in mice.",
            "journal": "Molecular brain",
            "date": "2022",
            "authors": "Nakashima A, Nakashima N, Nakashima K, Takano M",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001161975",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001161975"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "35379313",
                    "url": "https://glygen.org/publication/PubMed/35379313"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "mmu:170639",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:170639",
            "resource": "KEGG Pathway"
        },
        {
            "id": "R-MMU-381753",
            "name": "Olfactory Signaling Pathway",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-381753",
            "resource": "Reactome",
            "description": "Olfactory Signaling Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "O88628-1",
            "protein_name": "Olfactory receptor 51E2",
            "gene_name": "Or51e2",
            "tax_id": 10116,
            "organism": "Rattus norvegicus",
            "sequence": {
                "sequence": "MSSCNFTHATFMLIGIPGLEEAHFWFGFPLLSMYAVALFGNCIVVFIVRTERSLHAPMYLFLCMLAAIDLALSTSTMPKILALFWFDSREITFDACLAQMFFIHALSAIESTILLAMAFDRYVAICHPLRHAAVLNNTVTVQIGMVALVRGSLFFFPLPLLIKRLAFCHSNVLSHSYCVHQDVMKLAYTDTLPNVVYGLTAILLVMGVDVMFISLSYFLIIRAVLQLPSKSERAKAFGTCVSHIGVVLAFYVPLIGLSVVHRFGNSLDPIVHVLMGDVYLLLPPVINPIIYGAKTKQIRTRVLAMFKISCDKDIEAGGNT",
                "length": 320
            },
            "evidence": [
                {
                    "id": "45224798",
                    "url": "http://www.informatics.jax.org/homology/45224798",
                    "database": "MGI"
                }
            ],
            "common_name": "Rat"
        },
        {
            "uniprot_canonical_ac": "Q9H255-1",
            "protein_name": "Olfactory receptor 51E2",
            "gene_name": "OR51E2",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MSSCNFTHATFVLIGIPGLEKAHFWVGFPLLSMYVVAMFGNCIVVFIVRTERSLHAPMYLFLCMLAAIDLALSTSTMPKILALFWFDSREISFEACLTQMFFIHALSAIESTILLAMAFDRYVAICHPLRHAAVLNNTVTAQIGIVAVVRGSLFFFPLPLLIKRLAFCHSNVLSHSYCVHQDVMKLAYADTLPNVVYGLTAILLVMGVDVMFISLSYFLIIRTVLQLPSKSERAKAFGTCVSHIGVVLAFYVPLIGLSVVHRFGNSLHPIVRVVMGDIYLLLPPVINPIIYGAKTKQIRTRVLAMFKISCDKDLQAVGGK",
                "length": 320
            },
            "evidence": [
                {
                    "id": "45224798",
                    "url": "http://www.informatics.jax.org/homology/45224798",
                    "database": "MGI"
                },
                {
                    "id": "Q8VBV9",
                    "url": "https://omabrowser.org/oma/group/Q8VBV9/",
                    "database": "OMA"
                }
            ],
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Biological Process",
                "total": 10,
                "go_terms": [
                    {
                        "name": "positive regulation of renin secretion into blood stream",
                        "id": "GO:1900135",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900135",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8VBV9",
                                "url": "https://www.uniprot.org/uniprot/Q8VBV9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "melanocyte proliferation",
                        "id": "GO:0097325",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097325",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8VBV9",
                                "url": "https://www.uniprot.org/uniprot/Q8VBV9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "G protein-coupled receptor signaling pathway",
                        "id": "GO:0007186",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8VBV9",
                                "url": "https://www.uniprot.org/uniprot/Q8VBV9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cell migration",
                        "id": "GO:0016477",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8VBV9",
                                "url": "https://www.uniprot.org/uniprot/Q8VBV9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of blood pressure",
                        "id": "GO:0045777",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045777",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8VBV9",
                                "url": "https://www.uniprot.org/uniprot/Q8VBV9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "steroid hormone mediated signaling pathway",
                        "id": "GO:0043401",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043401",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8VBV9",
                                "url": "https://www.uniprot.org/uniprot/Q8VBV9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "sensory perception of smell",
                        "id": "GO:0007608",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007608",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8VBV9",
                                "url": "https://www.uniprot.org/uniprot/Q8VBV9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of cAMP-mediated signaling",
                        "id": "GO:0043950",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043950",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8VBV9",
                                "url": "https://www.uniprot.org/uniprot/Q8VBV9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "melanocyte differentiation",
                        "id": "GO:0030318",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030318",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8VBV9",
                                "url": "https://www.uniprot.org/uniprot/Q8VBV9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cellular response to fatty acid",
                        "id": "GO:0071398",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071398",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8VBV9",
                                "url": "https://www.uniprot.org/uniprot/Q8VBV9"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 4,
                "go_terms": [
                    {
                        "name": "G protein-coupled receptor activity",
                        "id": "GO:0004930",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8VBV9",
                                "url": "https://www.uniprot.org/uniprot/Q8VBV9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "nuclear steroid receptor activity",
                        "id": "GO:0003707",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003707",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8VBV9",
                                "url": "https://www.uniprot.org/uniprot/Q8VBV9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "olfactory receptor activity",
                        "id": "GO:0004984",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8VBV9",
                                "url": "https://www.uniprot.org/uniprot/Q8VBV9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "signaling receptor activity",
                        "id": "GO:0038023",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8VBV9",
                                "url": "https://www.uniprot.org/uniprot/Q8VBV9"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 4,
                "go_terms": [
                    {
                        "name": "plasma membrane",
                        "id": "GO:0005886",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8VBV9",
                                "url": "https://www.uniprot.org/uniprot/Q8VBV9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "membrane",
                        "id": "GO:0016020",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8VBV9",
                                "url": "https://www.uniprot.org/uniprot/Q8VBV9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "early endosome membrane",
                        "id": "GO:0031901",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8VBV9",
                                "url": "https://www.uniprot.org/uniprot/Q8VBV9"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "intracellular organelle",
                        "id": "GO:0043229",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043229",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8VBV9",
                                "url": "https://www.uniprot.org/uniprot/Q8VBV9"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 136,
            "end_pos": 138,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 5,
            "end_pos": 7,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        },
        {
            "name": "homologset.oma",
            "label": "OMA Homologs"
        }
    ],
    "section_stats": [
        {
            "table_id": "glycosylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 1
                },
                {
                    "field": "total_sites",
                    "count": 1
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 1
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
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                }
            ],
            "sort_fields": [
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                "type",
                "subtype",
                "site_category",
                "site_seq",
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                "comment",
                "start_pos",
                "start_aa",
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        },
        {
            "table_id": "glycosylation_reported",
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                    "field": "n_linked_glycan_sites",
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                {
                    "field": "o_linked_glycans",
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                },
                {
                    "field": "o_linked_glycan_sites",
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                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported_with_glycan",
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                    "field": "o_linked_glycan_sites",
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            "sort_fields": []
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        {
            "table_id": "glycosylation_predicted",
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        {
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        {
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        {
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    ]
}