{
    "uniprot_canonical_ac": "Q8R173-1",
    "uniprot_ac": "Q8R173",
    "uniprot_id": "ZDHC3_MOUSE",
    "mass": {
        "chemical_mass": 34041.0,
        "monoisotopic_mass": 34041.0
    },
    "refseq": {
        "ac": "NP_081193",
        "name": "palmitoyltransferase ZDHHC3 isoform 2",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_081193"
    },
    "gene_names": [
        {
            "name": "Zdhhc3",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/Q8R173",
            "id": "Q8R173"
        },
        {
            "name": "1110020O22Rik; 1810006O10Rik; 2210017C02Rik; DHHC-3; GODZ; Gramp1; Zfp373",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_081193",
            "id": "NP_081193"
        },
        {
            "name": "Godz",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/Q8R173",
            "id": "Q8R173"
        },
        {
            "name": "Gramp1",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/Q8R173",
            "id": "Q8R173"
        },
        {
            "name": "Zdhhc3",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_081193",
            "id": "NP_081193"
        }
    ],
    "protein_names": [
        {
            "name": "Palmitoyltransferase ZDHHC3",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "Q8R173"
        },
        {
            "name": "2.3.1.-",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q8R173"
        },
        {
            "name": "2.3.1.225",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q8R173"
        },
        {
            "name": "Acyltransferase ZDHHC3",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q8R173"
        },
        {
            "name": "DHHC-3",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q8R173"
        },
        {
            "name": "GABA-A receptor-associated membrane protein 1",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q8R173"
        },
        {
            "name": "Golgi-specific DHHC zinc finger protein",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q8R173"
        },
        {
            "name": "Zinc finger DHHC domain-containing protein 3",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "Q8R173"
        },
        {
            "name": "palmitoyltransferase ZDHHC3 isoform 2",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_081193",
            "id": "NP_081193"
        },
        {
            "name": "palmitoyltransferase ZDHHC3; GABA-A receptor-associated membrane protein 1; golgi-specific DHHC zinc finger protein; zinc finger DHHC domain-containing protein 3; acyltransferase ZDHHC3",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_081193",
            "id": "NP_081193"
        }
    ],
    "function": [
        {
            "annotation": "Absence of zinc finger protein GODZ affects primary and latent infection, as well as reactivation, in ocularly infected mice. The reduced virus infectivity is due to the absence of the GODZ interaction with HSV-1 UL20. These results strongly suggest that binding of UL20 to GODZ promotes virus infectivity in vitro and viral pathogenesis in vivo. Publication Status: Online-Only",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_081193",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_081193"
                },
                {
                    "database": "PubMed",
                    "id": "29187538",
                    "url": "https://glygen.org/publication/PubMed/29187538"
                }
            ]
        },
        {
            "annotation": "GODZ-mediated palmitoylation is a novel posttranslational modification that is selective for gamma-subunit-containing GABA(A) receptor subtypes, a mechanism that may be important for regulated trafficking of these receptors in the secretory pathway.",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_081193",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_081193"
                },
                {
                    "database": "PubMed",
                    "id": "15229235",
                    "url": "https://glygen.org/publication/PubMed/15229235"
                }
            ]
        },
        {
            "annotation": "GODZ-mediated palmitoylation of GABA(A) receptor gamma 2 subunit, and possibly other substrates, contributes selectively to the formation and normal function of GABAergic inhibitory synapses.",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_081193",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_081193"
                },
                {
                    "database": "PubMed",
                    "id": "17151279",
                    "url": "https://glygen.org/publication/PubMed/17151279"
                }
            ]
        },
        {
            "annotation": "Golgi-localized palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates (PubMed:15229235, PubMed:15603741, PubMed:16129400, PubMed:19001095, PubMed:23793055, PubMed:25253725, PubMed:26487721). Has no stringent fatty acid selectivity and in addition to palmitate can also transfer onto target proteins myristate from tetradecanoyl-CoA and stearate from octadecanoyl-CoA (Probable). Plays an important role in G protein-coupled receptor signaling pathways involving GNAQ and potentially other heterotrimeric G proteins by regulating their dynamic association with the plasma membrane (PubMed:19001095). Palmitoylates ITGA6 and ITGB4, thereby regulating the alpha-6/beta-4 integrin localization, expression and function in cell adhesion to laminin (By similarity). Plays a role in the TRAIL-activated apoptotic signaling pathway most probably through the palmitoylation and localization to the plasma membrane of TNFRSF10A (By similarity). In the brain, by palmitoylating the gamma subunit GABRG2 of GABA(A) receptors and regulating their postsynaptic accumulation, plays a role in synaptic GABAergic inhibitory function and GABAergic innervation (PubMed:15229235, PubMed:17151279, PubMed:27875292). Palmitoylates the neuronal protein GAP43 which is also involved in the formation of GABAergic synapses (PubMed:27875292). Palmitoylates NCDN thereby regulating its association with endosome membranes (PubMed:23687301). Probably palmitoylates PRCD and is involved in its proper localization within the photoreceptor (PubMed:27613864). Could mediate the palmitoylation of NCAM1 and regulate neurite outgrowth (PubMed:27247265). Could palmitoylate DNAJC5 and regulate its localization to Golgi membranes (PubMed:18596047). Also constitutively palmitoylates DLG4 (PubMed:15603741). May also palmitoylate SNAP25 (PubMed:25253725). Could palmitoylate the glutamate receptors GRIA1 and GRIA2 but this has not been confirmed in vivo (PubMed:16129400, PubMed:27875292). Could also palmitoylate the D(2) dopamine receptor DRD2 (By similarity). May also palmitoylate LAMTOR1, promoting its localization to lysosomal membranes (By similarity).",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8R173",
                    "url": "https://www.uniprot.org/uniprot/Q8R173#function"
                },
                {
                    "database": "PubMed",
                    "id": "15603741",
                    "url": "https://glygen.org/publication/PubMed/15603741"
                },
                {
                    "database": "PubMed",
                    "id": "16129400",
                    "url": "https://glygen.org/publication/PubMed/16129400"
                },
                {
                    "database": "PubMed",
                    "id": "27875292",
                    "url": "https://glygen.org/publication/PubMed/27875292"
                },
                {
                    "database": "PubMed",
                    "id": "23793055",
                    "url": "https://glygen.org/publication/PubMed/23793055"
                },
                {
                    "database": "PubMed",
                    "id": "17151279",
                    "url": "https://glygen.org/publication/PubMed/17151279"
                },
                {
                    "database": "PubMed",
                    "id": "15229235",
                    "url": "https://glygen.org/publication/PubMed/15229235"
                },
                {
                    "database": "PubMed",
                    "id": "27247265",
                    "url": "https://glygen.org/publication/PubMed/27247265"
                },
                {
                    "database": "PubMed",
                    "id": "25253725",
                    "url": "https://glygen.org/publication/PubMed/25253725"
                },
                {
                    "database": "UniProtKB",
                    "id": "Q9NYG2",
                    "url": "https://www.uniprot.org/uniprot/Q9NYG2#function"
                },
                {
                    "database": "PubMed",
                    "id": "26487721",
                    "url": "https://glygen.org/publication/PubMed/26487721"
                },
                {
                    "database": "PubMed",
                    "id": "19001095",
                    "url": "https://glygen.org/publication/PubMed/19001095"
                },
                {
                    "database": "PubMed",
                    "id": "28167757",
                    "url": "https://glygen.org/publication/PubMed/28167757"
                },
                {
                    "database": "PubMed",
                    "id": "23687301",
                    "url": "https://glygen.org/publication/PubMed/23687301"
                },
                {
                    "database": "PubMed",
                    "id": "27613864",
                    "url": "https://glygen.org/publication/PubMed/27613864"
                },
                {
                    "database": "PubMed",
                    "id": "18596047",
                    "url": "https://glygen.org/publication/PubMed/18596047"
                }
            ]
        },
        {
            "annotation": "Loss of GODZ expression is associated with reduced Palmitoylation of GABA type A receptors .",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_081193",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_081193"
                },
                {
                    "database": "PubMed",
                    "id": "27875292",
                    "url": "https://glygen.org/publication/PubMed/27875292"
                }
            ]
        },
        {
            "annotation": "May also function as a calcium transporter.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8R173",
                    "url": "https://www.uniprot.org/uniprot/Q8R173#function"
                },
                {
                    "database": "PubMed",
                    "id": "19955568",
                    "url": "https://glygen.org/publication/PubMed/19955568"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [
        {
            "start_pos": 129,
            "end_pos": 129,
            "sequence_org": "C",
            "sequence_mut": "S",
            "comment": "No effect on ZDHHC3 palmitoylation. Changed protein structure. Decreased protein-cysteine S-palmitoyltransferase activity.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8R173",
                    "url": "https://www.uniprot.org/uniprot/Q8R173"
                },
                {
                    "database": "PubMed",
                    "id": "26487721",
                    "url": "https://glygen.org/publication/PubMed/26487721"
                }
            ]
        },
        {
            "start_pos": 132,
            "end_pos": 132,
            "sequence_org": "C",
            "sequence_mut": "S",
            "comment": "No effect on ZDHHC3 palmitoylation. Changed protein structure. Decreased protein-cysteine S-palmitoyltransferase activity.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8R173",
                    "url": "https://www.uniprot.org/uniprot/Q8R173"
                },
                {
                    "database": "PubMed",
                    "id": "26487721",
                    "url": "https://glygen.org/publication/PubMed/26487721"
                }
            ]
        },
        {
            "start_pos": 133,
            "end_pos": 133,
            "sequence_org": "C",
            "sequence_mut": "S",
            "comment": "No effect on ZDHHC3 palmitoylation. No effect on protein-cysteine S-palmitoyltransferase activity.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8R173",
                    "url": "https://www.uniprot.org/uniprot/Q8R173"
                },
                {
                    "database": "PubMed",
                    "id": "26487721",
                    "url": "https://glygen.org/publication/PubMed/26487721"
                }
            ]
        },
        {
            "start_pos": 146,
            "end_pos": 146,
            "sequence_org": "C",
            "sequence_mut": "S",
            "comment": "Decreased ZDHHC3 palmitoylation. Changed protein structure. Decreased protein-cysteine S-palmitoyltransferase activity.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8R173",
                    "url": "https://www.uniprot.org/uniprot/Q8R173"
                },
                {
                    "database": "PubMed",
                    "id": "26487721",
                    "url": "https://glygen.org/publication/PubMed/26487721"
                }
            ]
        },
        {
            "start_pos": 157,
            "end_pos": 157,
            "sequence_org": "C",
            "sequence_mut": "S",
            "comment": "Loss of protein-cysteine S-acyltransferase activity. Loss of ZDHHC3 palmitoylation.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8R173",
                    "url": "https://www.uniprot.org/uniprot/Q8R173"
                },
                {
                    "database": "PubMed",
                    "id": "16129400",
                    "url": "https://glygen.org/publication/PubMed/16129400"
                },
                {
                    "database": "PubMed",
                    "id": "23793055",
                    "url": "https://glygen.org/publication/PubMed/23793055"
                },
                {
                    "database": "PubMed",
                    "id": "28167757",
                    "url": "https://glygen.org/publication/PubMed/28167757"
                },
                {
                    "database": "PubMed",
                    "id": "19001095",
                    "url": "https://glygen.org/publication/PubMed/19001095"
                }
            ]
        },
        {
            "start_pos": 182,
            "end_pos": 184,
            "sequence_org": "ISL",
            "sequence_mut": "SSV",
            "comment": "Increased protein-cysteine S-stearoyltransferase activity.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8R173",
                    "url": "https://www.uniprot.org/uniprot/Q8R173"
                },
                {
                    "database": "PubMed",
                    "id": "28167757",
                    "url": "https://glygen.org/publication/PubMed/28167757"
                }
            ]
        },
        {
            "start_pos": 18,
            "end_pos": 18,
            "sequence_org": "Y",
            "sequence_mut": "F",
            "comment": "Decreased phosphorylation by FGFR1.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8R173",
                    "url": "https://www.uniprot.org/uniprot/Q8R173"
                },
                {
                    "database": "PubMed",
                    "id": "27247265",
                    "url": "https://glygen.org/publication/PubMed/27247265"
                }
            ]
        },
        {
            "start_pos": 295,
            "end_pos": 295,
            "sequence_org": "Y",
            "sequence_mut": "F",
            "comment": "Decreased phosphorylation by SRC and increased autopalmitoylation; when associated with F-297.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8R173",
                    "url": "https://www.uniprot.org/uniprot/Q8R173"
                },
                {
                    "database": "PubMed",
                    "id": "27247265",
                    "url": "https://glygen.org/publication/PubMed/27247265"
                }
            ]
        },
        {
            "start_pos": 297,
            "end_pos": 297,
            "sequence_org": "Y",
            "sequence_mut": "F",
            "comment": "Decreased phosphorylation by SRC and increased autopalmitoylation; when associated with F-295.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8R173",
                    "url": "https://www.uniprot.org/uniprot/Q8R173"
                },
                {
                    "database": "PubMed",
                    "id": "27247265",
                    "url": "https://glygen.org/publication/PubMed/27247265"
                }
            ]
        },
        {
            "start_pos": 61,
            "end_pos": 61,
            "sequence_org": "V",
            "sequence_mut": "R",
            "comment": "Loss of function in calcium transport.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8R173",
                    "url": "https://www.uniprot.org/uniprot/Q8R173"
                },
                {
                    "database": "PubMed",
                    "id": "19955568",
                    "url": "https://glygen.org/publication/PubMed/19955568"
                }
            ]
        }
    ],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8R173",
                    "url": "https://www.uniprot.org/uniprot/Q8R173"
                }
            ],
            "common_name": "Mouse"
        }
    ],
    "gene": [
        {
            "name": "Zdhhc3",
            "url": "https://www.uniprot.org/uniprot/Q8R173",
            "locus": {
                "chromosome": "9",
                "start_pos": 122895225,
                "end_pos": 122942270,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSMUSG00000025786",
                        "url": "https://www.ensembl.org/id/ENSMUSG00000025786"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSMUSG00000025786",
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000025786",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "2.3.1.225",
            "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.1.225&UniProtAcc=Q8R173",
            "database": "BRENDA",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "69035",
            "url": "https://www.ncbi.nlm.nih.gov/gene/69035",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "Q8R173",
            "url": "https://www.ebi.ac.uk/intact/interactors/id:Q8R173*",
            "database": "IntAct",
            "categories": [
                "Other"
            ]
        },
        {
            "id": "IPR001594",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001594",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "mmu:69035",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:69035",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "1926134",
            "url": "http://www.informatics.jax.org/marker/MGI:1926134",
            "database": "MGI",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "VCVVMTW",
            "url": "https://omabrowser.org/oma/group/VCVVMTW/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "6683at2759",
            "url": "http://www.orthodb.org/?query=6683at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR22883",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22883",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR22883:SF246",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22883:SF246",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF01529",
            "url": "http://pfam.xfam.org/family/PF01529",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_Q8R173",
            "url": "http://purl.obolibrary.org/obo/PR_Q8R173",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "NP_081193",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_081193",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "36683",
            "url": "https://www.rhea-db.org/rhea/36683",
            "database": "Rhea",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "59736",
            "url": "https://www.rhea-db.org/rhea/59736",
            "database": "Rhea",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "59740",
            "url": "https://www.rhea-db.org/rhea/59740",
            "database": "Rhea",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "A0A571BEV7",
            "url": "https://www.uniprot.org/uniprot/A0A571BEV7",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A571BEV7-1",
            "url": "https://www.uniprot.org/uniprot/A0A571BEV7-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "D3Z2A6",
            "url": "https://www.uniprot.org/uniprot/D3Z2A6",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "D3Z2A6-1",
            "url": "https://www.uniprot.org/uniprot/D3Z2A6-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "D6RDS4",
            "url": "https://www.uniprot.org/uniprot/D6RDS4",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "D6RDS4-1",
            "url": "https://www.uniprot.org/uniprot/D6RDS4-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "D6RFV6",
            "url": "https://www.uniprot.org/uniprot/D6RFV6",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "D6RFV6-1",
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            "id": "D6RHA3",
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        },
        {
            "id": "D6RHA3-1",
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            "categories": [
                "Protein"
            ]
        },
        {
            "id": "D6RHS2",
            "url": "https://www.uniprot.org/uniprot/D6RHS2",
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            "categories": [
                "Protein"
            ]
        },
        {
            "id": "D6RHS2-1",
            "url": "https://www.uniprot.org/uniprot/D6RHS2-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "F6Q2M4",
            "url": "https://www.uniprot.org/uniprot/F6Q2M4",
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        },
        {
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        },
        {
            "id": "Q05D46",
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            ]
        },
        {
            "id": "Q05D46-1",
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            ]
        },
        {
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            ]
        },
        {
            "id": "Q8R173-1",
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            ]
        }
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        "length": 299,
        "header": "sp|Q8R173-1|ZDHC3_MOUSE Isoform 1 of Palmitoyltransferase ZDHHC3  OS=Mus musculus OX=10090 GN=Zdhhc3 PE=1 SV=1 CANONICAL=Q8R173-1"
    },
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        {
            "isoform_ac": "A0A571BEV7-1",
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                "length": 332,
                "header": "tr|A0A571BEV7-1|A0A571BEV7_MOUSE Computationally mapped isoform of Palmitoyltransferase  OS=Mus musculus OX=10090 GN=Zdhhc3 PE=1 SV=1 CANONICAL=Q8R173-1"
            },
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                        "id": "ENSMUST00000238520.2",
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                    {
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                        "id": "ENSMUSP00000158842.2",
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                "header": "tr|D3Z2A6-1|ZDHC3_MOUSE Computationally mapped isoform of Palmitoyltransferase ZDHHC3  OS=Mus musculus OX=10090 GN=Zdhhc3 PE=1 SV=1 CANONICAL=Q8R173-1"
            },
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                "chromosome": "9",
                "start_pos": 122929633,
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                        "id": "ENSMUST00000130717.2",
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                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000121712.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000121712.2"
                    }
                ]
            }
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        {
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                "length": 122,
                "header": "tr|D6RDS4-1|ZDHC3_MOUSE Computationally mapped isoform of Palmitoyltransferase ZDHHC3  OS=Mus musculus OX=10090 GN=Zdhhc3 PE=1 SV=1 CANONICAL=Q8R173-1"
            },
            "locus": {
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                    {
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                        "id": "ENSMUST00000138622.8",
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                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000119750.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000119750.2"
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                ]
            }
        },
        {
            "isoform_ac": "D6RFV6-1",
            "url": "",
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                "sequence": "MMLIPTHHFRDIERKPEYLQPEKCAPPPFPGPAGAMWFIRDGCGIACAIVTWFLVLYAEFVVLFVMLVPSRDYAYSIINGIVFNLLAFLALASHCRAMLTDPVRGSAQRKCH",
                "length": 112,
                "header": "tr|D6RFV6-1|D6RFV6_MOUSE Computationally mapped isoform of Zinc finger, DHHC domain containing 3  OS=Mus musculus OX=10090 GN=Zdhhc3 PE=4 SV=1 CANONICAL=Q8R173-1"
            },
            "locus": {
                "chromosome": "9",
                "start_pos": 122929633,
                "end_pos": 122918196,
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                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000140497.8",
                        "url": "https://www.ensembl.org/id/ENSMUST00000140497.8"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000122604.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000122604.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "D6RHA3-1",
            "url": "",
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                "length": 128,
                "header": "tr|D6RHA3-1|D6RHA3_MOUSE Computationally mapped isoform of Zinc finger, DHHC domain containing 3  OS=Mus musculus OX=10090 GN=Zdhhc3 PE=4 SV=1 CANONICAL=Q8R173-1"
            },
            "locus": {
                "chromosome": "9",
                "start_pos": 122929633,
                "end_pos": 122918196,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000026892.15",
                        "url": "https://www.ensembl.org/id/ENSMUST00000026892.15"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000026892.9",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000026892.9"
                    }
                ]
            }
        },
        {
            "isoform_ac": "D6RHS2-1",
            "url": "",
            "sequence": {
                "sequence": "MMLIPTHHFRDIERKPEYLQPEKCAPPPFPGPAGAMWFIRDGCGIACAIVTWFLVLYAEFVVLFVMLVPSRDYAYSIINGIVFNLLAFLALASHCRAMLTDPLTVQYRLSHQDASVGKTVFVSGAFARWITTVLGSTTVSARTTRSTLSYSQCT",
                "length": 154,
                "header": "tr|D6RHS2-1|D6RHS2_MOUSE Computationally mapped isoform of Zinc finger, DHHC domain containing 3  OS=Mus musculus OX=10090 GN=Zdhhc3 PE=4 SV=1 CANONICAL=Q8R173-1"
            },
            "locus": {
                "chromosome": "9",
                "start_pos": 122929633,
                "end_pos": 122912685,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000152396.8",
                        "url": "https://www.ensembl.org/id/ENSMUST00000152396.8"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000116222.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000116222.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "F6Q2M4-1",
            "url": "",
            "sequence": {
                "sequence": "AYSIINGIVFNLLAFLALASHCRAMLTDPVTHSSVPALPSRCLCWKDRGQCPKEMPLKSSSRAFS",
                "length": 65,
                "header": "tr|F6Q2M4-1|ZDHC3_MOUSE Computationally mapped isoform of Palmitoyltransferase ZDHHC3  OS=Mus musculus OX=10090 GN=Zdhhc3 PE=1 SV=1 CANONICAL=Q8R173-1"
            },
            "locus": {
                "chromosome": "9",
                "start_pos": 122929414,
                "end_pos": 122918170,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000129862.2",
                        "url": "https://www.ensembl.org/id/ENSMUST00000129862.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000119360.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000119360.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q05D46-1",
            "url": "",
            "sequence": {
                "sequence": "MMLIPTHHFRDIERKPEYLQPEKCAPPPFPGPAGAMWFIRDGCGIACAIVTWFLVLYAEFVVLFVMLVPSRDYAYSIINGIVFNLLAFLALASHCRAMLTDPCL",
                "length": 104,
                "header": "tr|Q05D46-1|ZDHC3_MOUSE Computationally mapped isoform of Palmitoyltransferase ZDHHC3  OS=Mus musculus OX=10090 GN=Zdhhc3 PE=1 SV=1 CANONICAL=Q8R173-1"
            },
            "locus": {
                "chromosome": "9",
                "start_pos": 122929633,
                "end_pos": 122913370,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000155778.8",
                        "url": "https://www.ensembl.org/id/ENSMUST00000155778.8"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000119416.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000119416.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q8R173-1",
            "url": "",
            "sequence": {
                "sequence": "MMLIPTHHFRDIERKPEYLQPEKCAPPPFPGPAGAMWFIRDGCGIACAIVTWFLVLYAEFVVLFVMLVPSRDYAYSIINGIVFNLLAFLALASHCRAMLTDPGAVPKGNATKEFIESLQLKPGQVVYKCPKCCSIKPDRAHHCSVCKRCIRKMDHHCPWVNNCVGENNQKYFVLFTMYIALISLHALIMVGFHFLHCFEEDWTKCSSFSPPTTVILLILLCFEALLFLIFTSVMFGTQVHSICTDETGIEQLKKEERRWAKKTKWMNMKAVFGHPFSLGWASPFATPDQGKADPYQYVV",
                "length": 299,
                "header": "sp|Q8R173-1|ZDHC3_MOUSE Isoform 1 of Palmitoyltransferase ZDHHC3  OS=Mus musculus OX=10090 GN=Zdhhc3 PE=1 SV=1 CANONICAL=Q8R173-1"
            },
            "locus": {
                "chromosome": "9",
                "start_pos": 122929633,
                "end_pos": 122907231,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000147563",
                        "url": "https://www.ensembl.org/id/ENSMUST00000147563"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000117392",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000117392"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [
        {
            "start_pos": 18,
            "end_pos": 18,
            "kinase_uniprot_canonical_ac": "",
            "kinase_gene_name": "",
            "residue": "Tyr",
            "comment": "Phosphotyrosine; by FGFR1",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8R173",
                    "url": "https://www.uniprot.org/uniprot/Q8R173"
                },
                {
                    "database": "iPTMnet",
                    "id": "Q8R173",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8R173"
                },
                {
                    "database": "PubMed",
                    "id": "27247265",
                    "url": "https://glygen.org/publication/PubMed/27247265"
                }
            ],
            "site_lbl": "Tyr18"
        }
    ],
    "glycation": [],
    "keywords": [
        "enzyme"
    ],
    "publication": [
        {
            "title": "Isolation and characterization of Golgi apparatus-specific GODZ with the DHHC zinc finger domain.",
            "journal": "Biochem. Biophys. Res. Commun.",
            "date": "2002",
            "authors": "Uemura T, Mori H, Mishina M",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8R173",
                    "url": "https://www.uniprot.org/uniprot/Q8R173"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "12163046",
                    "url": "https://glygen.org/publication/PubMed/12163046"
                }
            ]
        },
        {
            "title": "The gamma2 subunit of GABA(A) receptors is a substrate for palmitoylation by GODZ.",
            "journal": "J. Neurosci.",
            "date": "2004",
            "authors": "Keller CA, Yuan X, Panzanelli P, Martin ML, Alldred M, Sassoe-Pognetto M, Luscher B",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8R173",
                    "url": "https://www.uniprot.org/uniprot/Q8R173"
                },
                {
                    "database": "RefSeq",
                    "id": "NP_081193",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_081193"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "15229235",
                    "url": "https://glygen.org/publication/PubMed/15229235"
                }
            ]
        },
        {
            "title": "Identification of PSD-95 palmitoylating enzymes.",
            "journal": "Neuron",
            "date": "2004",
            "authors": "Fukata M, Fukata Y, Adesnik H, Nicoll RA, Bredt DS",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8R173",
                    "url": "https://www.uniprot.org/uniprot/Q8R173"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "15603741",
                    "url": "https://glygen.org/publication/PubMed/15603741"
                }
            ]
        },
        {
            "title": "Differential regulation of AMPA receptor subunit trafficking by palmitoylation of two distinct sites.",
            "journal": "Neuron",
            "date": "2005",
            "authors": "Hayashi T, Rumbaugh G, Huganir RL",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8R173",
                    "url": "https://www.uniprot.org/uniprot/Q8R173"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "16129400",
                    "url": "https://glygen.org/publication/PubMed/16129400"
                }
            ]
        },
        {
            "title": "GODZ-mediated palmitoylation of GABA(A) receptors is required for normal assembly and function of GABAergic inhibitory synapses.",
            "journal": "J. Neurosci.",
            "date": "2006",
            "authors": "Fang C, Deng L, Keller CA, Fukata M, Fukata Y, Chen G, Luscher B",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8R173",
                    "url": "https://www.uniprot.org/uniprot/Q8R173"
                },
                {
                    "database": "RefSeq",
                    "id": "NP_081193",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_081193"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "17151279",
                    "url": "https://glygen.org/publication/PubMed/17151279"
                }
            ]
        },
        {
            "title": "Palmitoylation and membrane interactions of the neuroprotective chaperone cysteine-string protein.",
            "journal": "J. Biol. Chem.",
            "date": "2008",
            "authors": "Greaves J, Salaun C, Fukata Y, Fukata M, Chamberlain LH",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8R173",
                    "url": "https://www.uniprot.org/uniprot/Q8R173"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "18596047",
                    "url": "https://glygen.org/publication/PubMed/18596047"
                }
            ]
        },
        {
            "title": "Identification of G protein alpha subunit-palmitoylating enzyme.",
            "journal": "Mol. Cell. Biol.",
            "date": "2009",
            "authors": "Tsutsumi R, Fukata Y, Noritake J, Iwanaga T, Perez F, Fukata M",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8R173",
                    "url": "https://www.uniprot.org/uniprot/Q8R173"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "19001095",
                    "url": "https://glygen.org/publication/PubMed/19001095"
                }
            ]
        },
        {
            "title": "Golgi-specific DHHC zinc finger protein GODZ mediates membrane Ca2+ transport.",
            "journal": "J. Biol. Chem.",
            "date": "2010",
            "authors": "Hines RM, Kang R, Goytain A, Quamme GA",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8R173",
                    "url": "https://www.uniprot.org/uniprot/Q8R173"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "19955568",
                    "url": "https://glygen.org/publication/PubMed/19955568"
                }
            ]
        },
        {
            "title": "In silico screening for palmitoyl substrates reveals a role for DHHC1/3/10 (zDHHC1/3/11)-mediated neurochondrin palmitoylation in its targeting to Rab5-positive endosomes.",
            "journal": "J. Biol. Chem.",
            "date": "2013",
            "authors": "Oku S, Takahashi N, Fukata Y, Fukata M",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8R173",
                    "url": "https://www.uniprot.org/uniprot/Q8R173"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "23687301",
                    "url": "https://glygen.org/publication/PubMed/23687301"
                }
            ]
        },
        {
            "title": "Oligomerization of DHHC protein S-acyltransferases.",
            "journal": "J. Biol. Chem.",
            "date": "2013",
            "authors": "Lai J, Linder ME",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8R173",
                    "url": "https://www.uniprot.org/uniprot/Q8R173"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "23793055",
                    "url": "https://glygen.org/publication/PubMed/23793055"
                }
            ]
        },
        {
            "title": "The Golgi S-acylation machinery comprises zDHHC enzymes with major differences in substrate affinity and S-acylation activity.",
            "journal": "Mol. Biol. Cell",
            "date": "2014",
            "authors": "Lemonidis K, Gorleku OA, Sanchez-Perez MC, Grefen C, Chamberlain LH",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8R173",
                    "url": "https://www.uniprot.org/uniprot/Q8R173"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "25253725",
                    "url": "https://glygen.org/publication/PubMed/25253725"
                }
            ]
        },
        {
            "title": "The Cysteine-rich Domain of the DHHC3 Palmitoyltransferase Is Palmitoylated and Contains Tightly Bound Zinc.",
            "journal": "J. Biol. Chem.",
            "date": "2015",
            "authors": "Gottlieb CD, Zhang S, Linder ME",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8R173",
                    "url": "https://www.uniprot.org/uniprot/Q8R173"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "26487721",
                    "url": "https://glygen.org/publication/PubMed/26487721"
                }
            ]
        },
        {
            "title": "ZDHHC3 Tyrosine Phosphorylation Regulates Neural Cell Adhesion Molecule Palmitoylation.",
            "journal": "Mol. Cell. Biol.",
            "date": "2016",
            "authors": "Lievens PM, Kuznetsova T, Kochlamazashvili G, Cesca F, Gorinski N, Galil DA, Cherkas V, Ronkina N, Lafera J, Gaestel M, Ponimaskin E, Dityatev A",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8R173",
                    "url": "https://www.uniprot.org/uniprot/Q8R173"
                },
                {
                    "database": "iPTMnet",
                    "id": "Q8R173",
                    "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8R173"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "27247265",
                    "url": "https://glygen.org/publication/PubMed/27247265"
                }
            ]
        },
        {
            "title": "Palmitoylation of Progressive Rod-Cone Degeneration (PRCD) Regulates Protein Stability and Localization.",
            "journal": "J. Biol. Chem.",
            "date": "2016",
            "authors": "Murphy J, Kolandaivelu S",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8R173",
                    "url": "https://www.uniprot.org/uniprot/Q8R173"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "27613864",
                    "url": "https://glygen.org/publication/PubMed/27613864"
                }
            ]
        },
        {
            "title": "Dissociation of Golgi-associated DHHC-type Zinc Finger Protein (GODZ)- and Sertoli Cell Gene with a Zinc Finger Domain-beta (SERZ-beta)-mediated Palmitoylation by Loss of Function Analyses in Knock-out Mice.",
            "journal": "J. Biol. Chem.",
            "date": "2016",
            "authors": "Kilpatrick CL, Murakami S, Feng M, Wu X, Lal R, Chen G, Du K, Luscher B",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8R173",
                    "url": "https://www.uniprot.org/uniprot/Q8R173"
                },
                {
                    "database": "RefSeq",
                    "id": "NP_081193",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_081193"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "27875292",
                    "url": "https://glygen.org/publication/PubMed/27875292"
                }
            ]
        },
        {
            "title": "Molecular basis of fatty acid selectivity in the zDHHC family of S-acyltransferases revealed by click chemistry.",
            "journal": "Proc. Natl. Acad. Sci. U.S.A.",
            "date": "2017",
            "authors": "Greaves J, Munro KR, Davidson SC, Riviere M, Wojno J, Smith TK, Tomkinson NC, Chamberlain LH",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8R173",
                    "url": "https://www.uniprot.org/uniprot/Q8R173"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "28167757",
                    "url": "https://glygen.org/publication/PubMed/28167757"
                }
            ]
        },
        {
            "title": "The Absence of DHHC3 Affects Primary and Latent Herpes Simplex Virus 1 Infection.",
            "journal": "Journal of virology",
            "date": "2018",
            "authors": "Wang S, Mott KR, Cilluffo M, Kilpatrick CL, Murakami S, Ljubimov AV, Kousoulas KG, Awasthi S, Luscher B, Ghiasi H",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_081193",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_081193"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "29187538",
                    "url": "https://glygen.org/publication/PubMed/29187538"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "mmu:69035",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:69035",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q2TGK3-1",
            "protein_name": "Palmitoyltransferase ZDHHC3",
            "gene_name": "Zdhhc3",
            "tax_id": 10116,
            "organism": "Rattus norvegicus",
            "sequence": {
                "sequence": "MMLIPTHHFRDIERKPEYLQPEKCAPPPFPGPVGTMWFIRDGCGIACAIVTWFLVLYAEFVVLFVMLIPSRDYAYSIINGIVFNLLAFLALASHCRAMLTDPGAVPKGNATKEFIESLQLKPGQVVYKCPKCCSIKPDRAHHCSVCKRCIRKMDHHCPWVNNCVGENNQKYFVLFTMYIALISLHALIMVGFHFLHCFEEDWTKCSSFSPPTTVILLILLCFEALLFLIFTSVMFGTQVHSICTDETGIEQLKKEERRWAKKTKWMNMKAVFGHPFSLGWASPFATPDQGKADPYQYVV",
                "length": 299
            },
            "evidence": [
                {
                    "id": "45232941",
                    "url": "http://www.informatics.jax.org/homology/45232941",
                    "database": "MGI"
                }
            ],
            "common_name": "Rat"
        },
        {
            "uniprot_canonical_ac": "Q9NYG2-1",
            "protein_name": "Palmitoyltransferase ZDHHC3",
            "gene_name": "ZDHHC3",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MMLIPTHHFRNIERKPEYLQPEKCVPPPYPGPVGTMWFIRDGCGIACAIVTWFLVLYAEFVVLFVMLIPSRDYVYSIINGIVFNLLAFLALASHCRAMLTDPGAVPKGNATKEFIESLQLKPGQVVYKCPKCCSIKPDRAHHCSVCKRCIRKMDHHCPWVNNCVGENNQKYFVLFTMYIALISLHALIMVGFHFLHCFEEDWTKCSSFSPPTTVILLILLCFEGLLFLIFTSVMFGTQVHSICTDETGIEQLKKEERRWAKKTKWMNMKAVFGHPFSLGWASPFATPDQGKADPYQYVV",
                "length": 299
            },
            "evidence": [
                {
                    "id": "45232941",
                    "url": "http://www.informatics.jax.org/homology/45232941",
                    "database": "MGI"
                }
            ],
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Cellular Component",
                "total": 4,
                "go_terms": [
                    {
                        "name": "membrane",
                        "id": "GO:0016020",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8R173",
                                "url": "https://www.uniprot.org/uniprot/Q8R173"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "Golgi membrane",
                        "id": "GO:0000139",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8R173",
                                "url": "https://www.uniprot.org/uniprot/Q8R173"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "endoplasmic reticulum",
                        "id": "GO:0005783",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8R173",
                                "url": "https://www.uniprot.org/uniprot/Q8R173"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "Golgi apparatus",
                        "id": "GO:0005794",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8R173",
                                "url": "https://www.uniprot.org/uniprot/Q8R173"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 5,
                "go_terms": [
                    {
                        "name": "protein homodimerization activity",
                        "id": "GO:0042803",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8R173",
                                "url": "https://www.uniprot.org/uniprot/Q8R173"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "protein-cysteine S-palmitoyltransferase activity",
                        "id": "GO:0019706",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019706",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8R173",
                                "url": "https://www.uniprot.org/uniprot/Q8R173"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "palmitoyltransferase activity",
                        "id": "GO:0016409",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016409",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8R173",
                                "url": "https://www.uniprot.org/uniprot/Q8R173"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "protein-cysteine S-myristoyltransferase activity",
                        "id": "GO:0019705",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019705",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8R173",
                                "url": "https://www.uniprot.org/uniprot/Q8R173"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "protein-cysteine S-stearoyltransferase activity",
                        "id": "GO:0140439",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140439",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8R173",
                                "url": "https://www.uniprot.org/uniprot/Q8R173"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 11,
                "go_terms": [
                    {
                        "name": "protein localization to plasma membrane",
                        "id": "GO:0072659",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8R173",
                                "url": "https://www.uniprot.org/uniprot/Q8R173"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "protein targeting",
                        "id": "GO:0006605",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006605",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8R173",
                                "url": "https://www.uniprot.org/uniprot/Q8R173"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "protein targeting to membrane",
                        "id": "GO:0006612",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006612",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8R173",
                                "url": "https://www.uniprot.org/uniprot/Q8R173"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of synaptic transmission, GABAergic",
                        "id": "GO:0032230",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032230",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8R173",
                                "url": "https://www.uniprot.org/uniprot/Q8R173"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "TRAIL-activated apoptotic signaling pathway",
                        "id": "GO:0036462",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036462",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8R173",
                                "url": "https://www.uniprot.org/uniprot/Q8R173"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of receptor localization to synapse",
                        "id": "GO:1902685",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902685",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8R173",
                                "url": "https://www.uniprot.org/uniprot/Q8R173"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "protein localization to photoreceptor outer segment",
                        "id": "GO:1903546",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903546",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8R173",
                                "url": "https://www.uniprot.org/uniprot/Q8R173"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "protein palmitoylation",
                        "id": "GO:0018345",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018345",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8R173",
                                "url": "https://www.uniprot.org/uniprot/Q8R173"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "peptidyl-L-cysteine S-palmitoylation",
                        "id": "GO:0018230",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018230",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8R173",
                                "url": "https://www.uniprot.org/uniprot/Q8R173"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "regulation of G protein-coupled receptor signaling pathway",
                        "id": "GO:0008277",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008277",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8R173",
                                "url": "https://www.uniprot.org/uniprot/Q8R173"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "lipoprotein localization to membrane",
                        "id": "GO:0044873",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044873",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "Q8R173",
                                "url": "https://www.uniprot.org/uniprot/Q8R173"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 109,
            "end_pos": 111,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [
        {
            "annotation": "Autopalmitoylated.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8R173",
                    "url": "https://www.uniprot.org/uniprot/Q8R173"
                },
                {
                    "database": "PubMed",
                    "id": "16129400",
                    "url": "https://glygen.org/publication/PubMed/16129400"
                },
                {
                    "database": "PubMed",
                    "id": "15229235",
                    "url": "https://glygen.org/publication/PubMed/15229235"
                },
                {
                    "database": "PubMed",
                    "id": "27247265",
                    "url": "https://glygen.org/publication/PubMed/27247265"
                },
                {
                    "database": "PubMed",
                    "id": "25253725",
                    "url": "https://glygen.org/publication/PubMed/25253725"
                }
            ]
        },
        {
            "annotation": "Phosphorylation by FGFR1 and SRC probably regulates the palmitoyltransferase activity.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "Q8R173",
                    "url": "https://www.uniprot.org/uniprot/Q8R173"
                },
                {
                    "database": "PubMed",
                    "id": "27247265",
                    "url": "https://glygen.org/publication/PubMed/27247265"
                }
            ]
        }
    ],
    "interactions": [],
    "reactions": [
        {
            "id": "36683",
            "name": "",
            "equation": "hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-hexadecanoyl-L-cysteinyl-[protein]",
            "summary": "",
            "cellular_location": "",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "P09606-1",
                "Q2TGI8-1",
                "Q2TGJ1-1",
                "Q2TGJ4-1",
                "Q2THW7-1",
                "Q2TGI5-1",
                "Q5FVR1-1",
                "E9PTT0-1",
                "Q2THW6-1",
                "Q32PY5-1",
                "Q6DGF5-1",
                "Q2TGK3-1",
                "Q76IC6-1",
                "Q923G5-1",
                "Q9JKR5-1",
                "A0A8I6AR22-1",
                "A0A8I6ALH7-1",
                "Q2TGJ5-1",
                "A0A8I6G4A8-1",
                "E9PU37-1",
                "Q2TGJ0-1",
                "Q2TGI4-1",
                "F7F533-1",
                "F7F2Z1-1",
                "A0A8I6G292-1",
                "A6J842-1",
                "Q8WTX9-1",
                "Q9NXF8-1",
                "Q9ULC8-1",
                "Q9Y397-1",
                "Q9H8X9-1",
                "Q8IZN3-1",
                "Q9NUE0-1",
                "Q6UX98-1",
                "Q9C0B5-1",
                "Q9H6R6-1",
                "Q96GR4-1",
                "Q9UIJ5-1",
                "Q8IYP9-1",
                "Q969W1-1",
                "P15104-1",
                "Q96MV8-1",
                "Q8IUH5-1",
                "Q5W0Z9-1",
                "Q9NPG8-1",
                "Q9NYG2-1",
                "Q8IUH4-1",
                "P0C7U3-1",
                "Q8WVZ1-1",
                "Q8IVQ6-1",
                "Q8N966-1",
                "Q9ESG8-1",
                "P15105-1",
                "P59267-1",
                "Q91WU6-1",
                "Q8VC90-1",
                "Q8VDZ4-1",
                "Q810M4-1",
                "Q8R0N9-1",
                "Q8R173-1",
                "Q8BQQ1-1",
                "Q810M5-1",
                "Q5Y5T3-1",
                "Q80TN5-1",
                "Q8BGJ0-1",
                "A0PK84-1",
                "Q6IR37-1",
                "Q9D270-1",
                "P59268-1",
                "Q9D6H5-1",
                "Q14AK4-1",
                "Q5Y5T5-1",
                "Q5Y5T1-1",
                "Q5Y5T2-1",
                "Q9CPV7-1",
                "Q9CWU2-1",
                "P39010-1",
                "P42836-1",
                "Q04629-1",
                "Q06551-1",
                "Q12006-1",
                "Q03289-1",
                "Q12013-1",
                "Q54JY9-1",
                "Q54PF0-1",
                "Q54RL6-1",
                "Q54X19-1",
                "Q54YH2-1",
                "Q555N7-1",
                "Q54B34-1",
                "Q54VH7-1",
                "Q550R7-1",
                "Q552M6-1",
                "Q554E7-1",
                "Q557H5-1",
                "Q86A83-1",
                "Q8T2Q0-1",
                "Q9VUW9-1",
                "Q9W345-1",
                "A2VEY9-1",
                "Q9VBM6-1",
                "A0A4D6K4L3-1",
                "A0A0B4LF16-1",
                "A1ZAR2-1",
                "Q9W251-1",
                "Q8IQN9-1",
                "Q7K3T4-1",
                "Q9VQK9-1",
                "Q9VBM5-1",
                "Q9VSV3-1",
                "Q9VBM4-1",
                "Q9VG80-1",
                "Q9I7L7-1",
                "Q9VBM8-1",
                "Q9VKN8-1",
                "Q9VB73-1",
                "Q0IGS7-1",
                "Q9VBM7-1"
            ],
            "evidence": [
                {
                    "id": "36683",
                    "database": "Rhea",
                    "url": "https://www.rhea-db.org/rhea/36683"
                }
            ]
        },
        {
            "id": "59736",
            "name": "",
            "equation": "L-cysteinyl-[protein] + tetradecanoyl-CoA = CoA + S-tetradecanoyl-L-cysteinyl-[protein]",
            "summary": "",
            "cellular_location": "",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "E9PTT0-1",
                "Q2TGJ4-1",
                "Q923G5-1",
                "Q9JKR5-1",
                "Q2TGK3-1",
                "Q96MV8-1",
                "Q8IUH5-1",
                "Q5W0Z9-1",
                "Q9NYG2-1",
                "Q9NXF8-1",
                "Q9UIJ5-1",
                "P59267-1",
                "Q91WU6-1",
                "Q8R173-1",
                "Q80TN5-1",
                "Q8BGJ0-1",
                "Q5Y5T1-1"
            ],
            "evidence": [
                {
                    "id": "59736",
                    "database": "Rhea",
                    "url": "https://www.rhea-db.org/rhea/59736"
                }
            ]
        },
        {
            "id": "59740",
            "name": "",
            "equation": "L-cysteinyl-[protein] + octadecanoyl-CoA = CoA + S-octadecanoyl-L-cysteinyl-[protein]",
            "summary": "",
            "cellular_location": "",
            "input_participant_list": [],
            "output_participant_list": [],
            "enzyme_list": [
                "E9PTT0-1",
                "Q2TGJ4-1",
                "Q923G5-1",
                "Q9JKR5-1",
                "Q32PY5-1",
                "Q2TGK3-1",
                "Q9H6R6-1",
                "Q96MV8-1",
                "Q8IUH5-1",
                "Q5W0Z9-1",
                "Q9NYG2-1",
                "Q9NXF8-1",
                "Q9UIJ5-1",
                "P59267-1",
                "Q91WU6-1",
                "Q8R173-1",
                "Q80TN5-1",
                "Q8BGJ0-1",
                "Q5Y5T1-1",
                "Q9CPV7-1"
            ],
            "evidence": [
                {
                    "id": "59740",
                    "database": "Rhea",
                    "url": "https://www.rhea-db.org/rhea/59740"
                }
            ]
        }
    ],
    "reaction_participants": [],
    "reaction_enzymes": [
        {
            "uniprot_ac": "A0A0B4LF16",
            "gene_name": "Dmel\\CG1407",
            "activity": [
                {
                    "ec_number": "2.3.1.225",
                    "activity": "hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-hexadecanoyl-L-cysteinyl-[protein].",
                    "evidence": [
                        {
                            "id": "A0A0B4LF16",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A0B4LF16"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.225",
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                            "id": "A0A0B4LF16",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A0B4LF16"
                        }
                    ]
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            ]
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        {
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                    "ec_number": "2.3.1.225",
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                            "id": "A0A4D6K4L3",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A4D6K4L3"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.225",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A4D6K4L3"
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                    ]
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                    "ec_number": "2.3.1.225",
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                            "id": "A0A8I6ALH7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I6ALH7"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.225",
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                            "id": "A0A8I6ALH7",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I6ALH7"
                        }
                    ]
                }
            ]
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                {
                    "ec_number": "2.3.1.225",
                    "activity": "hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-hexadecanoyl-L-cysteinyl-[protein].",
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                            "id": "A0A8I6AR22",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I6AR22"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.225",
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                            "id": "A0A8I6AR22",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I6AR22"
                        }
                    ]
                }
            ]
        },
        {
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                {
                    "ec_number": "2.3.1.225",
                    "activity": "hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-hexadecanoyl-L-cysteinyl-[protein].",
                    "evidence": [
                        {
                            "id": "A0A8I6G292",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I6G292"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.225",
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                            "id": "A0A8I6G292",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I6G292"
                        }
                    ]
                }
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        },
        {
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                {
                    "ec_number": "2.3.1.225",
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                            "id": "A0A8I6G4A8",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I6G4A8"
                        }
                    ]
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                {
                    "ec_number": "2.3.1.225",
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                        {
                            "id": "A0A8I6G4A8",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0A8I6G4A8"
                        }
                    ]
                }
            ]
        },
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                {
                    "ec_number": "2.3.1.225",
                    "activity": "hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-hexadecanoyl-L-cysteinyl-[protein].",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0PK84"
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                    ]
                },
                {
                    "ec_number": "2.3.1.225",
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                            "id": "A0PK84",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A0PK84"
                        }
                    ]
                }
            ]
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            "uniprot_ac": "A1ZAR2",
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                    "ec_number": "2.3.1.225",
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                            "id": "A1ZAR2",
                            "database": "UniProtKB",
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                    ]
                },
                {
                    "ec_number": "2.3.1.225",
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                            "id": "A1ZAR2",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/A1ZAR2"
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                    ]
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        },
        {
            "uniprot_ac": "A2VEY9",
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                {
                    "ec_number": "2.3.1.225",
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                    "evidence": [
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                            "id": "A2VEY9",
                            "database": "UniProtKB",
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                        }
                    ]
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                {
                    "ec_number": "2.3.1.225",
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                            "id": "A2VEY9",
                            "database": "UniProtKB",
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                    "ec_number": "2.3.1.225",
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                            "id": "A6J842",
                            "database": "UniProtKB",
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                    ]
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                {
                    "ec_number": "2.3.1.225",
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                            "id": "A6J842",
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                    "ec_number": "2.3.1.225",
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                            "id": "E9PTT0",
                            "database": "UniProtKB",
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                {
                    "ec_number": "2.3.1.-",
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                    "ec_number": "2.3.1.225",
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                            "database": "UniProtKB",
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                    ]
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                    "ec_number": "2.3.1.225",
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                            "database": "UniProtKB",
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                    ]
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                {
                    "ec_number": "2.3.1.225",
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                    "ec_number": "2.3.1.225",
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                    ]
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                {
                    "ec_number": "2.3.1.225",
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                            "id": "F7F2Z1",
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                    "ec_number": "2.3.1.225",
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                            "id": "F7F533",
                            "database": "UniProtKB",
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                    ]
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                {
                    "ec_number": "2.3.1.225",
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                            "id": "F7F533",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/F7F533"
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                {
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                            "id": "P09606",
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                            "url": "https://www.uniprot.org/uniprot/P09606"
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                {
                    "ec_number": "6.3.1.2",
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                            "id": "P09606",
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                            "database": "UniProtKB",
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                    ]
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                    "ec_number": "2.3.1.225",
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                            "id": "P0C7U3",
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                {
                    "ec_number": "2.3.1.225",
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                    ]
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                {
                    "ec_number": "6.3.1.2",
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                            "id": "P15104",
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                    ]
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                {
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                            "id": "P15104",
                            "database": "UniProtKB",
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                    ]
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                {
                    "ec_number": "6.3.1.2",
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                            "id": "P15104",
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                    "ec_number": "6.3.1.2",
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                            "id": "P15105",
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                    "ec_number": "2.3.1.225",
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                            "id": "P15105",
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                {
                    "ec_number": "6.3.1.2",
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                            "id": "P15105",
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                    "ec_number": "2.3.1.225",
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                            "id": "P15105",
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                    "ec_number": "2.3.1.225",
                    "activity": "hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-hexadecanoyl-L-cysteinyl-[protein].",
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                            "id": "P39010",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P39010"
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                {
                    "ec_number": "2.3.1.225",
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                            "id": "P39010",
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                    "ec_number": "2.3.1.225",
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                            "id": "P42836",
                            "database": "UniProtKB",
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                },
                {
                    "ec_number": "2.3.1.225",
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                            "id": "P42836",
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            "uniprot_ac": "P59267",
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                    "ec_number": "2.3.1.225",
                    "activity": "hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-hexadecanoyl-L-cysteinyl-[protein].",
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                            "id": "P59267",
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                            "url": "https://www.uniprot.org/uniprot/P59267"
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                },
                {
                    "ec_number": "2.3.1.-",
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                            "id": "P59267",
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                    ]
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                {
                    "ec_number": "2.3.1.225",
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                            "id": "P59267",
                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/P59267"
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                    ]
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        {
            "uniprot_ac": "P59268",
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                    "ec_number": "2.3.1.225",
                    "activity": "hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-hexadecanoyl-L-cysteinyl-[protein].",
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                    ]
                },
                {
                    "ec_number": "2.3.1.225",
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                            "id": "P59268",
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                    "ec_number": "2.3.1.225",
                    "activity": "hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-hexadecanoyl-L-cysteinyl-[protein].",
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                            "id": "Q03289",
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                {
                    "ec_number": "2.3.1.225",
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                            "id": "Q03289",
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                    "ec_number": "2.3.1.225",
                    "activity": "hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-hexadecanoyl-L-cysteinyl-[protein].",
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                            "id": "Q04629",
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                            "url": "https://www.uniprot.org/uniprot/Q04629"
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                    ]
                },
                {
                    "ec_number": "2.3.1.225",
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                            "id": "Q04629",
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                    "ec_number": "2.3.1.225",
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                            "id": "Q06551",
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                    ]
                },
                {
                    "ec_number": "2.3.1.225",
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                            "id": "Q06551",
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                    ]
                }
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        },
        {
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                    "ec_number": "2.3.1.225",
                    "activity": "hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-hexadecanoyl-L-cysteinyl-[protein].",
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                            "id": "Q0IGS7",
                            "database": "UniProtKB",
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                    ]
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                {
                    "ec_number": "2.3.1.225",
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        },
        {
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                {
                    "ec_number": "2.3.1.225",
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                            "database": "UniProtKB",
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                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.-",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5W0Z9"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.225",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5W0Z9"
                        }
                    ]
                }
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        },
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                    "ec_number": "2.3.1.225",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5Y5T1"
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                    ]
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                {
                    "ec_number": "2.3.1.-",
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                    ]
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                {
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5Y5T1"
                        }
                    ]
                }
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        },
        {
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                {
                    "ec_number": "2.3.1.225",
                    "activity": "hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-hexadecanoyl-L-cysteinyl-[protein].",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5Y5T2"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.225",
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                        }
                    ]
                }
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        },
        {
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                {
                    "ec_number": "2.3.1.225",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q5Y5T3"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.225",
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                        }
                    ]
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                            "database": "UniProtKB",
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                {
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                    "ec_number": "2.3.1.225",
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                            "database": "UniProtKB",
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                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.225",
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                        }
                    ]
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                    "ec_number": "2.3.1.225",
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                {
                    "ec_number": "2.3.1.225",
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                {
                    "ec_number": "2.3.1.225",
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                            "database": "UniProtKB",
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                {
                    "ec_number": "2.3.1.225",
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                {
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                {
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                {
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                    "ec_number": "2.3.1.225",
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                            "database": "UniProtKB",
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                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.-",
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                    ]
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                {
                    "ec_number": "2.3.1.225",
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                        }
                    ]
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                    "ec_number": "2.3.1.225",
                    "activity": "hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-hexadecanoyl-L-cysteinyl-[protein].",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8T2Q0"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.225",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8T2Q0"
                        }
                    ]
                }
            ]
        },
        {
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                {
                    "ec_number": "2.3.1.225",
                    "activity": "hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-hexadecanoyl-L-cysteinyl-[protein].",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8VC90"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.225",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8VC90"
                        }
                    ]
                }
            ]
        },
        {
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                    "ec_number": "2.3.1.225",
                    "activity": "hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-hexadecanoyl-L-cysteinyl-[protein].",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8VDZ4"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.225",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8VDZ4"
                        }
                    ]
                }
            ]
        },
        {
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                    "ec_number": "2.3.1.225",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8WTX9"
                        }
                    ]
                },
                {
                    "ec_number": "2.3.1.225",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8WTX9"
                        }
                    ]
                }
            ]
        },
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                    "ec_number": "2.3.1.225",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8WVZ1"
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                    ]
                },
                {
                    "ec_number": "2.3.1.225",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q8WVZ1"
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                    ]
                }
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        },
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                    "ec_number": "2.3.1.225",
                    "activity": "hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-hexadecanoyl-L-cysteinyl-[protein].",
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                            "database": "UniProtKB",
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                    ]
                },
                {
                    "ec_number": "2.3.1.-",
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                            "database": "UniProtKB",
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                {
                    "ec_number": "2.3.1.225",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q91WU6"
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q923G5"
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                    ]
                },
                {
                    "ec_number": "2.3.1.225",
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                            "database": "UniProtKB",
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                    ]
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                {
                    "ec_number": "2.3.1.-",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q923G5"
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                    ]
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                    "ec_number": "2.3.1.225",
                    "activity": "hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-hexadecanoyl-L-cysteinyl-[protein].",
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                            "database": "UniProtKB",
                            "url": "https://www.uniprot.org/uniprot/Q969W1"
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                {
                    "ec_number": "2.3.1.225",
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                            "url": "https://www.uniprot.org/uniprot/Q969W1"
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                    "ec_number": "2.3.1.225",
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                            "database": "UniProtKB",
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                {
                    "ec_number": "2.3.1.225",
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                            "database": "UniProtKB",
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                    "ec_number": "2.3.1.225",
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                {
                    "ec_number": "2.3.1.-",
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                            "database": "UniProtKB",
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                {
                    "ec_number": "2.3.1.225",
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                            "database": "UniProtKB",
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                {
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                {
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                            "database": "UniProtKB",
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                {
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                            "database": "UniProtKB",
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                    "ec_number": "2.3.1.225",
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                            "database": "UniProtKB",
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                    "ec_number": "2.3.1.-",
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                            "database": "UniProtKB",
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                            "database": "UniProtKB",
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                    "ec_number": "2.3.1.225",
                    "activity": "hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-hexadecanoyl-L-cysteinyl-[protein].",
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                    "ec_number": "2.3.1.-",
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                    ]
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                    "ec_number": "2.3.1.225",
                    "activity": "hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-hexadecanoyl-L-cysteinyl-[protein].",
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                {
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