{ "uniprot_canonical_ac": "Q8R080-1", "uniprot_ac": "Q8R080", "uniprot_id": "GTSE1_MOUSE", "mass": { "chemical_mass": 78751.0, "monoisotopic_mass": 78751.0 }, "refseq": { "ac": "NP_001162143", "name": "G2 and S phase-expressed protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001162143" }, "gene_names": [ { "name": "Gtse1", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/Q8R080", "id": "Q8R080" }, { "name": "B99; Gtse-1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001162143", "id": "NP_001162143" }, { "name": "B99", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/Q8R080", "id": "Q8R080" }, { "name": "Gtse1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001162143", "id": "NP_001162143" } ], "protein_names": [ { "name": "G2 and S phase-expressed protein 1", "resource": "UniProtKB", "type": "recommended", "url": "", "id": "Q8R080" }, { "name": "G2 and S phase-expressed protein 1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001162143", "id": "NP_001162143" }, { "name": "GTSE-1", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q8R080" }, { "name": "Protein B99", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "Q8R080" } ], "function": [ { "annotation": "Clathrin's adaptor interaction sites are repurposed to stabilize microtubules during mitosis.", "evidence": [ { "database": "RefSeq", "id": "NP_001162143", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001162143" }, { "database": "PubMed", "id": "31932847", "url": "https://glygen.org/publication/PubMed/31932847" } ] }, { "annotation": "May be involved in p53-induced cell cycle arrest in G2/M phase by interfering with microtubule rearrangements that are required to enter mitosis. Overexpression delays G2/M phase progression.", "evidence": [ { "database": "UniProtKB", "id": "Q8R080", "url": "https://www.uniprot.org/uniprot/Q8R080#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8R080", "url": "https://www.uniprot.org/uniprot/Q8R080" } ], "common_name": "Mouse" } ], "gene": [ { "name": "Gtse1", "url": "https://www.uniprot.org/uniprot/Q8R080", "locus": { "chromosome": "15", "start_pos": 85760774, "end_pos": 85743946, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSMUSG00000022385", "url": "https://www.ensembl.org/id/ENSMUSG00000022385" } ] } } ], "crossref": [ { "id": "ENSMUSG00000022385", "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000022385", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "29870", "url": "https://www.ncbi.nlm.nih.gov/gene/29870", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "Q8R080", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q8R080*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR026657", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026657", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032768", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032768", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "mmu:29870", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:29870", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "1352755", "url": "http://www.informatics.jax.org/marker/MGI:1352755", "database": "MGI", "categories": [ "Organism-specific" ] }, { "id": "MTPKMMP", "url": "https://omabrowser.org/oma/group/MTPKMMP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "4271844at2759", "url": "http://www.orthodb.org/?query=4271844at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21584", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21584", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21584:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21584:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15259", "url": "http://pfam.xfam.org/family/PF15259", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PR_Q8R080", "url": "http://purl.obolibrary.org/obo/PR_Q8R080", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-MMU-69481", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-69481", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "R-MMU-8852276", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-8852276", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "NP_001162143", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001162143", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q8R080", "url": "https://www.uniprot.org/uniprot/Q8R080", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q8R080-1", "url": "https://www.uniprot.org/uniprot/Q8R080-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDAGSKKEDFLLLEDEKFDFDLSLSSSSTNEDDEVFFGPVGHKERCIAASLDLNRRVPGQPLAPGSGSPCTLSPLTGEKFVEVYKEAHLLALQIESHSRREVAQAATPQNPVNQGKETFVQDSQLKVSLFEKEQKRDRSPMSLKRETFCLPSSRVQPPMGEPQLLASPGLLSSPVSAGPAQTQSNQGLPCSSQPLPRESSTSQPPSQAGPQKRITSKLQPPRALPVRGRNLHLATEKLKKEVPASIQRTKLVNEKGSQSDVLQDKPSTAPDAASREGHPGKRSLPIPGKLGLKKTLLKPPGYTGNLTRKSSTSGSASSLESGVYRSSVAGKAKSSEQRSSIPASGSQRRTSTSKSGRIGPAASRQALPAAPARVFGRQANKADAAQTVAEQPKVPTLSPLTQQPQTPEQRGPRLDPDTETPQLNKTVSIKRRDSYLSCKTEAVSTTTNPFKVPQFSVGESPGGVTPKFSRTHRLQSWTPASRVVSSTPVRRSSGTTPQGLPGSMRTPLSTRRMSVLPTPASRRLSSLPLMAPQSMPRALVSPLCVPARRLSSEPRRRSTVRAELTQESSGSGSGGQAQGLSSDESSSPPSSVPQALNFSPEKSASPPPQGSSTGAAQGEAEPPEDTLPSEVHGGGCSHTPSEGLLLDLKLDQLTITPEAGGRDLADCPLIDFSNTPESNTALGPSSWPLIDLIMNTPDMGRNDVGKPAKAELGQLIDLGSPLIQLSPEADKENVDSPLLKF", "length": 741, "header": "sp|Q8R080-1|GTSE1_MOUSE Isoform 1 of G2 and S phase-expressed protein 1 OS=Mus musculus OX=10090 GN=Gtse1 PE=1 SV=2 CANONICAL=Q8R080-1" }, "isoforms": [ { "isoform_ac": "Q8R080-1", "url": "", "sequence": { "sequence": "MDAGSKKEDFLLLEDEKFDFDLSLSSSSTNEDDEVFFGPVGHKERCIAASLDLNRRVPGQPLAPGSGSPCTLSPLTGEKFVEVYKEAHLLALQIESHSRREVAQAATPQNPVNQGKETFVQDSQLKVSLFEKEQKRDRSPMSLKRETFCLPSSRVQPPMGEPQLLASPGLLSSPVSAGPAQTQSNQGLPCSSQPLPRESSTSQPPSQAGPQKRITSKLQPPRALPVRGRNLHLATEKLKKEVPASIQRTKLVNEKGSQSDVLQDKPSTAPDAASREGHPGKRSLPIPGKLGLKKTLLKPPGYTGNLTRKSSTSGSASSLESGVYRSSVAGKAKSSEQRSSIPASGSQRRTSTSKSGRIGPAASRQALPAAPARVFGRQANKADAAQTVAEQPKVPTLSPLTQQPQTPEQRGPRLDPDTETPQLNKTVSIKRRDSYLSCKTEAVSTTTNPFKVPQFSVGESPGGVTPKFSRTHRLQSWTPASRVVSSTPVRRSSGTTPQGLPGSMRTPLSTRRMSVLPTPASRRLSSLPLMAPQSMPRALVSPLCVPARRLSSEPRRRSTVRAELTQESSGSGSGGQAQGLSSDESSSPPSSVPQALNFSPEKSASPPPQGSSTGAAQGEAEPPEDTLPSEVHGGGCSHTPSEGLLLDLKLDQLTITPEAGGRDLADCPLIDFSNTPESNTALGPSSWPLIDLIMNTPDMGRNDVGKPAKAELGQLIDLGSPLIQLSPEADKENVDSPLLKF", "length": 741, "header": "sp|Q8R080-1|GTSE1_MOUSE Isoform 1 of G2 and S phase-expressed protein 1 OS=Mus musculus OX=10090 GN=Gtse1 PE=1 SV=2 CANONICAL=Q8R080-1" }, "locus": { "chromosome": "15", "start_pos": 85760430, "end_pos": 85744272, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000170629", "url": "https://www.ensembl.org/id/ENSMUST00000170629" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000128759", "url": "https://www.ensembl.org/id/ENSMUSP00000128759" } ] } } ], "glycosylation": [], "phosphorylation": [ { "start_pos": 139, "end_pos": 139, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8R080", "url": "https://www.uniprot.org/uniprot/Q8R080" } ], "site_lbl": "Ser139" }, { "start_pos": 153, "end_pos": 153, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8R080", "url": "https://www.uniprot.org/uniprot/Q8R080" } ], "site_lbl": "Ser153" }, { "start_pos": 191, "end_pos": 191, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8R080", "url": "https://www.uniprot.org/uniprot/Q8R080" } ], "site_lbl": "Ser191" }, { "start_pos": 245, "end_pos": 245, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8R080", "url": "https://www.uniprot.org/uniprot/Q8R080" } ], "site_lbl": "Ser245" }, { "start_pos": 311, "end_pos": 311, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8R080", "url": "https://www.uniprot.org/uniprot/Q8R080" } ], "site_lbl": "Ser311" }, { "start_pos": 460, "end_pos": 460, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8R080", "url": "https://www.uniprot.org/uniprot/Q8R080" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q8R080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8R080" } ], "site_lbl": "Ser460" }, { "start_pos": 465, "end_pos": 465, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q8R080", "url": "https://www.uniprot.org/uniprot/Q8R080" }, { "database": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" }, { "database": "iPTMnet", "id": "Q8R080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8R080" } ], "site_lbl": "Thr465" }, { "start_pos": 476, "end_pos": 476, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8R080", "url": "https://www.uniprot.org/uniprot/Q8R080" }, { "database": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" }, { "database": "phospho.ELM", "id": "Q8R080", "url": "http://phospho.elm.eu.org/byAccession/Q8R080.html" }, { "database": "iPTMnet", "id": "Q8R080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8R080" } ], "site_lbl": "Ser476" }, { "start_pos": 493, "end_pos": 493, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8R080", "url": "https://www.uniprot.org/uniprot/Q8R080" } ], "site_lbl": "Ser493" }, { "start_pos": 509, "end_pos": 509, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8R080", "url": "https://www.uniprot.org/uniprot/Q8R080" } ], "site_lbl": "Ser509" }, { "start_pos": 514, "end_pos": 514, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8R080", "url": "https://www.uniprot.org/uniprot/Q8R080" } ], "site_lbl": "Ser514" }, { "start_pos": 518, "end_pos": 518, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q8R080", "url": "https://www.uniprot.org/uniprot/Q8R080" } ], "site_lbl": "Thr518" }, { "start_pos": 521, "end_pos": 521, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8R080", "url": "https://www.uniprot.org/uniprot/Q8R080" } ], "site_lbl": "Ser521" }, { "start_pos": 541, "end_pos": 541, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8R080", "url": "https://www.uniprot.org/uniprot/Q8R080" } ], "site_lbl": "Ser541" }, { "start_pos": 582, "end_pos": 582, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8R080", "url": "https://www.uniprot.org/uniprot/Q8R080" } ], "site_lbl": "Ser582" }, { "start_pos": 599, "end_pos": 599, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8R080", "url": "https://www.uniprot.org/uniprot/Q8R080" } ], "site_lbl": "Ser599" }, { "start_pos": 696, "end_pos": 696, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q8R080", "url": "https://www.uniprot.org/uniprot/Q8R080" } ], "site_lbl": "Thr696" }, { "start_pos": 720, "end_pos": 720, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8R080", "url": "https://www.uniprot.org/uniprot/Q8R080" } ], "site_lbl": "Ser720" }, { "start_pos": 726, "end_pos": 726, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8R080", "url": "https://www.uniprot.org/uniprot/Q8R080" }, { "database": "phospho.ELM", "id": "Q8R080", "url": "http://phospho.elm.eu.org/byAccession/Q8R080.html" }, { "database": "iPTMnet", "id": "Q8R080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8R080" }, { "database": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" } ], "site_lbl": "Ser726" }, { "start_pos": 736, "end_pos": 736, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8R080", "url": "https://www.uniprot.org/uniprot/Q8R080" } ], "site_lbl": "Ser736" }, { "start_pos": 73, "end_pos": 73, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q8R080", "url": "https://www.uniprot.org/uniprot/Q8R080" } ], "site_lbl": "Ser73" } ], "glycation": [], "keywords": [], "publication": [ { "title": "Cell-cycle regulation of the p53-inducible gene B99.", "journal": "FEBS Lett.", "date": "2000", "authors": "Collavin L, Monte M, Verardo R, Pfleger C, Schneider C", "evidence": [ { "database": "UniProtKB", "id": "Q8R080", "url": "https://www.uniprot.org/uniprot/Q8R080" } ], "reference": [ { "type": "PubMed", "id": "10984615", "url": "https://glygen.org/publication/PubMed/10984615" } ] }, { "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "2007", "authors": "Villen J, Beausoleil SA, Gerber SA, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8R080", "url": "https://www.uniprot.org/uniprot/Q8R080" } ], "reference": [ { "type": "PubMed", "id": "17242355", "url": "https://glygen.org/publication/PubMed/17242355" } ] }, { "title": "The phagosomal proteome in interferon-gamma-activated macrophages.", "journal": "Immunity", "date": "2009", "authors": "Trost M, English L, Lemieux S, Courcelles M, Desjardins M, Thibault P", "evidence": [ { "database": "UniProtKB", "id": "Q8R080", "url": "https://www.uniprot.org/uniprot/Q8R080" }, { "database": "iPTMnet", "id": "Q8R080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8R080" } ], "reference": [ { "type": "PubMed", "id": "19144319", "url": "https://glygen.org/publication/PubMed/19144319" } ] }, { "title": "A tissue-specific atlas of mouse protein phosphorylation and expression.", "journal": "Cell", "date": "2010", "authors": "Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villen J, Haas W, Sowa ME, Gygi SP", "evidence": [ { "database": "UniProtKB", "id": "Q8R080", "url": "https://www.uniprot.org/uniprot/Q8R080" }, { "database": "iPTMnet", "id": "Q8R080", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8R080" } ], "reference": [ { "type": "PubMed", "id": "21183079", "url": "https://glygen.org/publication/PubMed/21183079" } ] }, { "title": "Clathrin's adaptor interaction sites are repurposed to stabilize microtubules during mitosis.", "journal": "The Journal of cell biology", "date": "2020", "authors": "Rondelet A, Lin YC, Singh D, Porfetye AT, Thakur HC, Hecker A, Brinkert P, Schmidt N, Bendre S, Muller F, Mazul L, Widlund PO, Bange T, Hiller M, Vetter IR, Bird AW", "evidence": [ { "database": "RefSeq", "id": "NP_001162143", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001162143" } ], "reference": [ { "type": "PubMed", "id": "31932847", "url": "https://glygen.org/publication/PubMed/31932847" } ] }, { "title": "A novel p53-inducible gene coding for a microtubule-localized protein with G2-phase-specific expression.", "journal": "EMBO J.", "date": "1998", "authors": "Schneider C., Delia D., Collavin L., Lazarevic D., Utrera R.", "evidence": [ { "database": "UniProtKB", "id": "Q8R080", "url": "https://www.uniprot.org/uniprot/Q8R080" } ], "reference": [ { "type": "PubMed", "id": "9724637", "url": "https://glygen.org/publication/PubMed/9724637" } ] } ], "pathway": [ { "id": "mmu:29870", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:29870", "resource": "KEGG Pathway" }, { "id": "R-MMU-69481", "name": "G2/M Checkpoints", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-69481", "resource": "Reactome", "description": "G2/M Checkpoints" }, { "id": "R-MMU-8852276", "name": "The role of GTSE1 in G2/M progression after G2 checkpoint", "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-8852276", "resource": "Reactome", "description": "The role of GTSE1 in G2/M progression after G2 checkpoint" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZPA8-1", "protein_name": "G-2 and S-phase expressed 1", "gene_name": "Gtse1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MERRDGSDVPSTSQRGEVKMDPGSKKEDFLLLEDEKFDFDLSLSSSSANEDDEVFFGPVGHKERCIAASLDLNRQVPEQPLAPGSGSPCTWSPLTGEKFVEVYKEAHLLALQIECHSRREVAQAAKPRSAVSQAKETFVQDSQLKISLFEKEQKRDKSPLSLKRETFCLPSSRAQPLLGEPQLLASPGLPNSPLPAGPVQTQSTQGPPCSSQPPSQAGPQRRIMSKLQPPRALPVRGRNLFLATEKLKKEVPASLQQTKPLNEKGSQSDVLLDKPSTAPDAASREGRPGKRSLPVPGKLGLKKTLLKPPGYTSNLTKKSSTSGSASSLVSGVGRSPTAGKAKSSELSSIPASSSRRQSVTSKLGRVGLATSHQALPAAPARAFCRQAKKADAAQTVAEQPKALTPSPLAQQPQTPKHKGPRVDLDTETCQLNKTVSIKRQDSSLGCKTEAVSTTTNPFKVPQFSVGESPDRVTPKISRTHRLQSWTPAGRVVSSTPVRRLSGLTPQGLPSSMRTPLSTRRMSVLPTPASRRLSGLPLTAPQSMPRALVSPLCVPARRLSSEPRRRSTVRSELMQESSSNGSAGQSQGLSSDESSSPPSSVPQALNFSPEKSDFPPSQGSSTGTGQGEAEPHEDMHPSEVPGGECSSTPSEGLLLDIKLDQLTIAPEAGDRDLADCPLIDFSNTPESNMALGPSSWPLIDLIMNTPNMGRSDVGKPPKAELGQLIDLGSPLIQLSPEADKENVDSPLLKF", "length": 749 }, "evidence": [ { "id": "45238324", "url": "http://www.informatics.jax.org/homology/45238324", "database": "MGI" } ], "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9NYZ3-1", "protein_name": "G2 and S phase-expressed protein 1", "gene_name": "GTSE1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDDPKKEDILLLADEKFDFDLSLSSSSANEDDEVFFGPFGHKERCIAASLELNNPVPEQPPLPTSESPFAWSPLAGEKFVEVYKEAHLLALHIESSSRNQAAQAAKPEDPRSQGVERFIQESKLKINLFEKEKEMKKSPTSLKRETYYLSDSPLLGPPVGEPRLLASSPALPSSGAQARLTRAPGPPHSAHALPRESCTAHAASQAATQRKPGTKLLLPRAASVRGRSIPGAAEKPKKEIPASPSRTKIPAEKESHRDVLPDKPAPGAVNVPAAGSHLGQGKRAIPVPNKLGLKKTLLKAPGSTSNLARKSSSGPVWSGASSACTSPAVGKAKSSEFASIPANSSRPLSNISKSGRMGPAMLRPALPAGPVGASSWQAKRVDVSELAAEQLTAPPSASPTQPQTPEGGGQWLNSSCAWSESSQLNKTRSIRRRDSCLNSKTKVMPTPTNQFKIPKFSIGDSPDSSTPKLSRAQRPQSCTSVGRVTVHSTPVRRSSGPAPQSLLSAWRVSALPTPASRRCSGLPPMTPKTMPRAVGSPLCVPARRRSSEPRKNSAMRTEPTRESNRKTDSRLVDVSPDRGSPPSRVPQALNFSPEESDSTFSKSTATEVAREEAKPGGDAAPSEALLVDIKLEPLAVTPDAASQPLIDLPLIDFCDTPEAHVAVGSESRPLIDLMTNTPDMNKNVAKPSPVVGQLIDLSSPLIQLSPEADKENVDSPLLKF", "length": 720 }, "evidence": [ { "id": "45238324", "url": "http://www.informatics.jax.org/homology/45238324", "database": "MGI" } ], "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "Q8R080", "url": "https://www.uniprot.org/uniprot/Q8R080" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "Q8R080", "url": "https://www.uniprot.org/uniprot/Q8R080" } ], "pmid": "" }, { "name": "cytoplasmic microtubule", "id": "GO:0005881", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005881", "evidence": [ { "database": "UniProtKB", "id": "Q8R080", "url": "https://www.uniprot.org/uniprot/Q8R080" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 305, "end_pos": 307, "annotation": "n_glycosylation_sequon" }, { "start_pos": 424, "end_pos": 426, "annotation": "n_glycosylation_sequon" }, { "start_pos": 597, "end_pos": 599, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [ { "annotation": "Phosphorylated in mitosis.", "evidence": [ { "database": "UniProtKB", "id": "Q8R080", "url": "https://www.uniprot.org/uniprot/Q8R080" }, { "database": "PubMed", "id": "10984615", "url": "https://glygen.org/publication/PubMed/10984615" } ] } ], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "synthesized_glycans": [], "cluster_types": [ { "name": "homologset.mgi", "label": "MGI Homologs" } ], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 21 }, { "field": "total_sites", "count": 21 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }